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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for MAP4

check button Gene summary
Gene informationGene symbol

MAP4

Gene ID

4134

Gene namemicrotubule associated protein 4
Synonyms-
Cytomap

3p21.31

Type of geneprotein-coding
Descriptionmicrotubule-associated protein 4MAP-4
Modification date20180523
UniProtAcc

P27816

ContextPubMed: MAP4 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Exon skipping events across known transcript of Ensembl for MAP4 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for MAP4

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for MAP4

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_383293347894277:47894428:47894652:47894842:47896737:4789685047894652:47894842ENSG00000047849.17ENST00000429422.1
exon_skip_383297347893357:47894529:47894652:47894842:47896737:4789685047894652:47894842ENSG00000047849.17ENST00000383737.4,ENST00000426837.2,ENST00000264724.11,ENST00000360240.6
exon_skip_383301347898920:47899002:47908735:47908828:47910703:4791081747908735:47908828ENSG00000047849.17ENST00000426837.2,ENST00000264724.11,ENST00000360240.6,ENST00000395734.3
exon_skip_383303347898920:47899002:47908735:47908828:47912302:4791259547908735:47908828ENSG00000047849.17ENST00000420772.2,ENST00000335271.5,ENST00000441748.2
exon_skip_383314347908735:47908828:47910703:47910817:47912302:4791259547910703:47910817ENSG00000047849.17ENST00000426837.2,ENST00000264724.11,ENST00000360240.6,ENST00000395734.3
exon_skip_383318347912347:47912595:47912716:47912776:47913406:4791359047912716:47912776ENSG00000047849.17ENST00000383737.4,ENST00000335271.5,ENST00000383736.3,ENST00000429422.1,ENST00000441748.2,ENST00000426837.2,ENST00000264724.11,ENST00000360240.6,ENST00000395734.3
exon_skip_383324347913406:47913590:47917174:47917390:47918906:4791901347917174:47917390ENSG00000047849.17ENST00000383737.4,ENST00000383736.3,ENST00000429422.1,ENST00000426837.2,ENST00000264724.11,ENST00000360240.6,ENST00000395734.3
exon_skip_383334347918906:47919013:47950527:47953911:47956306:4795642947950527:47953911ENSG00000047849.17ENST00000426837.2
exon_skip_383336347918906:47919013:47956306:47956429:47957440:4795803147956306:47956429ENSG00000047849.17ENST00000360240.6,ENST00000395734.3
exon_skip_383347347918906:47919013:47963254:47963368:47969717:4796979247963254:47963368ENSG00000047849.17ENST00000482752.1
exon_skip_383359347956306:47956429:47957440:47958664:47960208:4796024147957440:47958664ENSG00000047849.17ENST00000426837.2,ENST00000360240.6,ENST00000395734.3
exon_skip_383367347958377:47958664:47960208:47960331:47963254:4796336847960208:47960331ENSG00000047849.17ENST00000383737.4,ENST00000426837.2,ENST00000360240.6,ENST00000395734.3
exon_skip_383368347958359:47958664:47960208:47960331:47969717:4796979247960208:47960331ENSG00000047849.17ENST00000423088.1
exon_skip_383372347960208:47960331:47963254:47963368:47969717:4796979247963254:47963368ENSG00000047849.17ENST00000383737.4,ENST00000426837.2,ENST00000360240.6,ENST00000395734.3
exon_skip_383373347963254:47963368:47969717:47969840:48019354:4801942347969717:47969840ENSG00000047849.17ENST00000383737.4,ENST00000426837.2,ENST00000360240.6,ENST00000395734.3
exon_skip_383376347969717:47969840:48019354:48019423:48028872:4802892348019354:48019423ENSG00000047849.17ENST00000426837.2
exon_skip_383377347969717:47969840:48019354:48019423:48040127:4804036948019354:48019423ENSG00000047849.17ENST00000423088.1,ENST00000383737.4,ENST00000360240.6,ENST00000395734.3
exon_skip_383384348019354:48019423:48028872:48028923:48040127:4804036948028872:48028923ENSG00000047849.17ENST00000426837.2
exon_skip_383386348019354:48019423:48040127:48040369:48130262:4813031448040127:48040369ENSG00000047849.17ENST00000439356.1,ENST00000360240.6,ENST00000395734.3

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for MAP4

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_383293347894277:47894428:47894652:47894842:47896737:4789685047894652:47894842ENSG00000047849.17ENST00000429422.1
exon_skip_383297347893357:47894529:47894652:47894842:47896737:4789685047894652:47894842ENSG00000047849.17ENST00000383737.4,ENST00000264724.11,ENST00000426837.2,ENST00000360240.6
exon_skip_383301347898920:47899002:47908735:47908828:47910703:4791081747908735:47908828ENSG00000047849.17ENST00000264724.11,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6
exon_skip_383303347898920:47899002:47908735:47908828:47912302:4791259547908735:47908828ENSG00000047849.17ENST00000420772.2,ENST00000335271.5,ENST00000441748.2
exon_skip_383314347908735:47908828:47910703:47910817:47912302:4791259547910703:47910817ENSG00000047849.17ENST00000264724.11,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6
exon_skip_383318347912347:47912595:47912716:47912776:47913406:4791359047912716:47912776ENSG00000047849.17ENST00000383737.4,ENST00000264724.11,ENST00000429422.1,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6,ENST00000335271.5,ENST00000441748.2,ENST00000383736.3
exon_skip_383324347913406:47913590:47917174:47917390:47918906:4791901347917174:47917390ENSG00000047849.17ENST00000383737.4,ENST00000264724.11,ENST00000429422.1,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6,ENST00000383736.3
exon_skip_383334347918906:47919013:47950527:47953911:47956306:4795642947950527:47953911ENSG00000047849.17ENST00000426837.2
exon_skip_383336347918906:47919013:47956306:47956429:47957440:4795803147956306:47956429ENSG00000047849.17ENST00000395734.3,ENST00000360240.6
exon_skip_383347347918906:47919013:47963254:47963368:47969717:4796979247963254:47963368ENSG00000047849.17ENST00000482752.1
exon_skip_383359347956306:47956429:47957440:47958664:47960208:4796024147957440:47958664ENSG00000047849.17ENST00000395734.3,ENST00000426837.2,ENST00000360240.6
exon_skip_383367347958377:47958664:47960208:47960331:47963254:4796336847960208:47960331ENSG00000047849.17ENST00000383737.4,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6
exon_skip_383368347958359:47958664:47960208:47960331:47969717:4796979247960208:47960331ENSG00000047849.17ENST00000423088.1
exon_skip_383372347960208:47960331:47963254:47963368:47969717:4796979247963254:47963368ENSG00000047849.17ENST00000383737.4,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6
exon_skip_383373347963254:47963368:47969717:47969840:48019354:4801942347969717:47969840ENSG00000047849.17ENST00000383737.4,ENST00000395734.3,ENST00000426837.2,ENST00000360240.6
exon_skip_383376347969717:47969840:48019354:48019423:48028872:4802892348019354:48019423ENSG00000047849.17ENST00000426837.2
exon_skip_383377347969717:47969840:48019354:48019423:48040127:4804036948019354:48019423ENSG00000047849.17ENST00000383737.4,ENST00000395734.3,ENST00000360240.6,ENST00000423088.1
exon_skip_383384348019354:48019423:48028872:48028923:48040127:4804036948028872:48028923ENSG00000047849.17ENST00000426837.2
exon_skip_383386348019354:48019423:48040127:48040369:48130262:4813031448040127:48040369ENSG00000047849.17ENST00000395734.3,ENST00000360240.6,ENST00000439356.1

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for MAP4

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000036024048040127480403693UTR-3CDS
ENST000003602404789465247894842Frame-shift
ENST000003602404790873547908828In-frame
ENST000003602404791070347910817In-frame
ENST000003602404791271647912776In-frame
ENST000003602404791717447917390In-frame
ENST000003602404795630647956429In-frame
ENST000003602404795744047958664In-frame
ENST000003602404796020847960331In-frame
ENST000003602404796325447963368In-frame
ENST000003602404796971747969840In-frame
ENST000003602404801935448019423In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000036024048040127480403693UTR-3CDS
ENST000003602404789465247894842Frame-shift
ENST000003602404790873547908828In-frame
ENST000003602404791070347910817In-frame
ENST000003602404791271647912776In-frame
ENST000003602404791717447917390In-frame
ENST000003602404795630647956429In-frame
ENST000003602404795744047958664In-frame
ENST000003602404796020847960331In-frame
ENST000003602404796325447963368In-frame
ENST000003602404796971747969840In-frame
ENST000003602404801935448019423In-frame

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Infer the effects of exon skipping event on protein functional features for MAP4

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003602405159115248019354480194237438117497
ENST0000036024051591152479697174796984081293497138
ENST000003602405159115247963254479633689351048138176
ENST0000036024051591152479602084796033110491171176217
ENST0000036024051591152479574404795866411722395217625
ENST0000036024051591152479574404795866411722395217625
ENST0000036024051591152479574404795866411722395217625
ENST0000036024051591152479563064795642923962518625666
ENST0000036024051591152479171744791739026262841702774
ENST0000036024051591152479127164791277630263085835855
ENST0000036024051591152479107034791081733793492953991
ENST00000360240515911524790873547908828349335859911022

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003602405159115248019354480194237438117497
ENST0000036024051591152479697174796984081293497138
ENST000003602405159115247963254479633689351048138176
ENST0000036024051591152479602084796033110491171176217
ENST0000036024051591152479574404795866411722395217625
ENST0000036024051591152479574404795866411722395217625
ENST0000036024051591152479574404795866411722395217625
ENST0000036024051591152479563064795642923962518625666
ENST0000036024051591152479171744791739026262841702774
ENST0000036024051591152479127164791277630263085835855
ENST0000036024051591152479107034791081733793492953991
ENST00000360240515911524790873547908828349335859911022

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
P2781674971151Alternative sequenceID=VSP_032065;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278167497182Alternative sequenceID=VSP_032066;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816749783221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P27816749721152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816971381151Alternative sequenceID=VSP_032065;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278169713883221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P27816971389899Alternative sequenceID=VSP_043240;Note=In isoform 7. GS->EA;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816971381001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278169713821152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816971389999Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
P278161381761151Alternative sequenceID=VSP_032065;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781613817683221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P278161381761001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816138176152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P2781613817621152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816138176160160Sequence conflictNote=A->R;Ontology_term=ECO:0000305;evidence=ECO:0000305
P2781617621783221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P278161762171001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816176217152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P2781617621721152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P2781621762583221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P2781621762583221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P2781621762583221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P278162176251001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278162176251001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278162176251001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816217625152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P27816217625152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P27816217625152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P27816217625225271Alternative sequenceID=VSP_032069;Note=In isoform 4. EIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTE->NGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816217625225271Alternative sequenceID=VSP_032069;Note=In isoform 4. EIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTE->NGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816217625225271Alternative sequenceID=VSP_032069;Note=In isoform 4. EIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTE->NGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816217625275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816217625275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816217625275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816217625322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816217625322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816217625322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816217625441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816217625441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816217625441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816217625558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816217625558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816217625558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P2781621762521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P2781621762521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P2781621762521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816217625269269Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:25114211;Dbxref=PMID:25114211
P27816217625269269Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:25114211;Dbxref=PMID:25114211
P27816217625269269Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:25114211;Dbxref=PMID:25114211
P27816217625253253Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816217625253253Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816217625253253Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816217625280280Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17693683,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625280280Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17693683,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625280280Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17693683,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625282282Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625282282Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625282282Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625354354Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625354354Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625354354Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625358358Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625358358Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625358358Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625380380Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625380380Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625380380Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625384384Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625384384Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625384384Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625440440Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625440440Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625440440Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625442442Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625442442Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625442442Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625507507Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,E
P27816217625507507Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,E
P27816217625507507Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,E
P27816217625510510Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
P27816217625510510Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
P27816217625510510Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
P27816217625521521Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18088087,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625521521Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18088087,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625521521Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18088087,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625526526Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625526526Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625526526Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625571571Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625571571Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625571571Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625580580Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
P27816217625580580Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
P27816217625580580Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
P27816217625585585Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:19690332,PMID:20068231,P
P27816217625585585Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:19690332,PMID:20068231,P
P27816217625585585Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:19690332,PMID:20068231,P
P27816217625624624Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625624624Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625624624Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625366366Natural variantID=VAR_039567;Note=P->L;Dbxref=dbSNP:rs13097415
P27816217625366366Natural variantID=VAR_039567;Note=P->L;Dbxref=dbSNP:rs13097415
P27816217625366366Natural variantID=VAR_039567;Note=P->L;Dbxref=dbSNP:rs13097415
P27816217625367367Natural variantID=VAR_039568;Note=S->P;Dbxref=dbSNP:rs13096947
P27816217625367367Natural variantID=VAR_039568;Note=S->P;Dbxref=dbSNP:rs13096947
P27816217625367367Natural variantID=VAR_039568;Note=S->P;Dbxref=dbSNP:rs13096947
P27816217625409409Natural variantID=VAR_039569;Note=D->G;Dbxref=dbSNP:rs13076542
P27816217625409409Natural variantID=VAR_039569;Note=D->G;Dbxref=dbSNP:rs13076542
P27816217625409409Natural variantID=VAR_039569;Note=D->G;Dbxref=dbSNP:rs13076542
P27816217625427427Natural variantID=VAR_020361;Note=S->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1060407,PMID:1718985
P27816217625427427Natural variantID=VAR_020361;Note=S->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1060407,PMID:1718985
P27816217625427427Natural variantID=VAR_020361;Note=S->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1060407,PMID:1718985
P27816217625441441Natural variantID=VAR_020362;Note=E->Q;Dbxref=dbSNP:rs2230169
P27816217625441441Natural variantID=VAR_020362;Note=E->Q;Dbxref=dbSNP:rs2230169
P27816217625441441Natural variantID=VAR_020362;Note=E->Q;Dbxref=dbSNP:rs2230169
P27816217625248545RegionNote=17 X 14 AA tandem repeats
P27816217625248545RegionNote=17 X 14 AA tandem repeats
P27816217625248545RegionNote=17 X 14 AA tandem repeats
P27816217625248261RepeatNote=1
P27816217625248261RepeatNote=1
P27816217625248261RepeatNote=1
P27816217625262275RepeatNote=2
P27816217625262275RepeatNote=2
P27816217625262275RepeatNote=2
P27816217625276289RepeatNote=3
P27816217625276289RepeatNote=3
P27816217625276289RepeatNote=3
P27816217625290303RepeatNote=4
P27816217625290303RepeatNote=4
P27816217625290303RepeatNote=4
P27816217625304317RepeatNote=5
P27816217625304317RepeatNote=5
P27816217625304317RepeatNote=5
P27816217625318331RepeatNote=6
P27816217625318331RepeatNote=6
P27816217625318331RepeatNote=6
P27816217625332345RepeatNote=7
P27816217625332345RepeatNote=7
P27816217625332345RepeatNote=7
P27816217625346351RepeatNote=8%3B truncated
P27816217625346351RepeatNote=8%3B truncated
P27816217625346351RepeatNote=8%3B truncated
P27816217625352377RepeatNote=26 residues 1
P27816217625352377RepeatNote=26 residues 1
P27816217625352377RepeatNote=26 residues 1
P27816217625378403RepeatNote=26 residues 2
P27816217625378403RepeatNote=26 residues 2
P27816217625378403RepeatNote=26 residues 2
P27816217625408421RepeatNote=9
P27816217625408421RepeatNote=9
P27816217625408421RepeatNote=9
P27816217625422433RepeatNote=10
P27816217625422433RepeatNote=10
P27816217625422433RepeatNote=10
P27816217625434447RepeatNote=11
P27816217625434447RepeatNote=11
P27816217625434447RepeatNote=11
P27816217625448461RepeatNote=12
P27816217625448461RepeatNote=12
P27816217625448461RepeatNote=12
P27816217625462475RepeatNote=13
P27816217625462475RepeatNote=13
P27816217625462475RepeatNote=13
P27816217625476489RepeatNote=14
P27816217625476489RepeatNote=14
P27816217625476489RepeatNote=14
P27816217625490503RepeatNote=15
P27816217625490503RepeatNote=15
P27816217625490503RepeatNote=15
P27816217625504517RepeatNote=16
P27816217625504517RepeatNote=16
P27816217625504517RepeatNote=16
P27816217625532545RepeatNote=17
P27816217625532545RepeatNote=17
P27816217625532545RepeatNote=17
P27816217625319319Sequence conflictNote=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305
P27816217625319319Sequence conflictNote=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305
P27816217625319319Sequence conflictNote=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305
P278166256661001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816625666275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816625666322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816625666441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816625666558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816625666635666Alternative sequenceID=VSP_032073;Note=In isoform 3. CSLPAEEDSVLEKLGERKPCNSQPSELSSETS->EIEVTATQSTPSFLFEKPPRD;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781662566621152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816625666636636Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:1
P27816625666643643Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816625666628628Natural variantID=VAR_039570;Note=V->I;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000269;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1137524,PMID:18669648,PMID:20068231,PMID:1718985
P278167027741001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816702774558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816702774703716Alternative sequenceID=VSP_032074;Note=In isoform 3. PLATTQPAKTSTSK->VGARMVVIFYCHNF;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278167027747171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781670277421152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816702774713713Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816702774723723Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P278168358551001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278168358557171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781683585521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816835855838838Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:28112733;Dbxref=PMID:28112733
P27816835855853853Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P278169539911001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278169539917171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816953991939953Alternative sequenceID=VSP_032076;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278169539919541022Alternative sequenceID=VSP_032077;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:17974005;Dbxref=PMID:17974005
P2781695399121152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816953991923953RepeatNote=Tau/MAP 1
P2781699110221001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P2781699110227171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781699110229541022Alternative sequenceID=VSP_032077;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:17974005;Dbxref=PMID:17974005
P27816991102221152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816991102210001000Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:24275569;Dbxref=PMID:21406692,PMID:24275569
P278169911022994994Natural variantID=VAR_039571;Note=I->V;Dbxref=dbSNP:rs35736893
P2781699110229921022RepeatNote=Tau/MAP 2


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
P2781674971151Alternative sequenceID=VSP_032065;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278167497182Alternative sequenceID=VSP_032066;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816749783221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P27816749721152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816971381151Alternative sequenceID=VSP_032065;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278169713883221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P27816971389899Alternative sequenceID=VSP_043240;Note=In isoform 7. GS->EA;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816971381001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278169713821152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816971389999Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
P278161381761151Alternative sequenceID=VSP_032065;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781613817683221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P278161381761001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816138176152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P2781613817621152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816138176160160Sequence conflictNote=A->R;Ontology_term=ECO:0000305;evidence=ECO:0000305
P2781617621783221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P278161762171001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816176217152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P2781617621721152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P2781621762583221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P2781621762583221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P2781621762583221Alternative sequenceID=VSP_032067;Note=In isoform 4. LLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLE->METTGDQGIEGMAYMDENRNITFTCPRTPSELINKSSPLEVLGSAACEKLPTPTPQVVKEGDSFPDT;Ontology_term
P278162176251001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278162176251001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278162176251001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816217625152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P27816217625152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P27816217625152437Alternative sequenceID=VSP_032068;Note=In isoform 3. LVFPSSATADTSIFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPP
P27816217625225271Alternative sequenceID=VSP_032069;Note=In isoform 4. EIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTE->NGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816217625225271Alternative sequenceID=VSP_032069;Note=In isoform 4. EIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTE->NGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816217625225271Alternative sequenceID=VSP_032069;Note=In isoform 4. EIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTE->NGQEIAPAQISKSLMVDNYTKDGVPGQERPKGPSAVVPSTSTGG;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816217625275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816217625275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816217625275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816217625322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816217625322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816217625322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816217625441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816217625441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816217625441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816217625558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816217625558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816217625558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P2781621762521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P2781621762521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P2781621762521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816217625269269Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:25114211;Dbxref=PMID:25114211
P27816217625269269Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:25114211;Dbxref=PMID:25114211
P27816217625269269Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:25114211;Dbxref=PMID:25114211
P27816217625253253Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816217625253253Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816217625253253Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816217625280280Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17693683,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625280280Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17693683,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625280280Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17693683,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625282282Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625282282Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625282282Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625354354Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625354354Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625354354Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625358358Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625358358Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625358358Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625380380Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625380380Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625380380Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625384384Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625384384Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625384384Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17924679,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,E
P27816217625440440Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625440440Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625440440Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625442442Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625442442Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625442442Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816217625507507Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,E
P27816217625507507Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,E
P27816217625507507Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,E
P27816217625510510Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
P27816217625510510Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
P27816217625510510Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
P27816217625521521Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18088087,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625521521Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18088087,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625521521Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18088087,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625526526Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625526526Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625526526Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692;Dbxref=PMID:20068231,PMID:21406692
P27816217625571571Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625571571Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625571571Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:16964243,ECO:0000244|PubMed:17081983,ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|Pu
P27816217625580580Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
P27816217625580580Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
P27816217625580580Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:23186163
P27816217625585585Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:19690332,PMID:20068231,P
P27816217625585585Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:19690332,PMID:20068231,P
P27816217625585585Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:19690332,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:19690332,PMID:20068231,P
P27816217625624624Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625624624Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625624624Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:20068231;Dbxref=PMID:20068231
P27816217625366366Natural variantID=VAR_039567;Note=P->L;Dbxref=dbSNP:rs13097415
P27816217625366366Natural variantID=VAR_039567;Note=P->L;Dbxref=dbSNP:rs13097415
P27816217625366366Natural variantID=VAR_039567;Note=P->L;Dbxref=dbSNP:rs13097415
P27816217625367367Natural variantID=VAR_039568;Note=S->P;Dbxref=dbSNP:rs13096947
P27816217625367367Natural variantID=VAR_039568;Note=S->P;Dbxref=dbSNP:rs13096947
P27816217625367367Natural variantID=VAR_039568;Note=S->P;Dbxref=dbSNP:rs13096947
P27816217625409409Natural variantID=VAR_039569;Note=D->G;Dbxref=dbSNP:rs13076542
P27816217625409409Natural variantID=VAR_039569;Note=D->G;Dbxref=dbSNP:rs13076542
P27816217625409409Natural variantID=VAR_039569;Note=D->G;Dbxref=dbSNP:rs13076542
P27816217625427427Natural variantID=VAR_020361;Note=S->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1060407,PMID:1718985
P27816217625427427Natural variantID=VAR_020361;Note=S->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1060407,PMID:1718985
P27816217625427427Natural variantID=VAR_020361;Note=S->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1060407,PMID:1718985
P27816217625441441Natural variantID=VAR_020362;Note=E->Q;Dbxref=dbSNP:rs2230169
P27816217625441441Natural variantID=VAR_020362;Note=E->Q;Dbxref=dbSNP:rs2230169
P27816217625441441Natural variantID=VAR_020362;Note=E->Q;Dbxref=dbSNP:rs2230169
P27816217625248545RegionNote=17 X 14 AA tandem repeats
P27816217625248545RegionNote=17 X 14 AA tandem repeats
P27816217625248545RegionNote=17 X 14 AA tandem repeats
P27816217625248261RepeatNote=1
P27816217625248261RepeatNote=1
P27816217625248261RepeatNote=1
P27816217625262275RepeatNote=2
P27816217625262275RepeatNote=2
P27816217625262275RepeatNote=2
P27816217625276289RepeatNote=3
P27816217625276289RepeatNote=3
P27816217625276289RepeatNote=3
P27816217625290303RepeatNote=4
P27816217625290303RepeatNote=4
P27816217625290303RepeatNote=4
P27816217625304317RepeatNote=5
P27816217625304317RepeatNote=5
P27816217625304317RepeatNote=5
P27816217625318331RepeatNote=6
P27816217625318331RepeatNote=6
P27816217625318331RepeatNote=6
P27816217625332345RepeatNote=7
P27816217625332345RepeatNote=7
P27816217625332345RepeatNote=7
P27816217625346351RepeatNote=8%3B truncated
P27816217625346351RepeatNote=8%3B truncated
P27816217625346351RepeatNote=8%3B truncated
P27816217625352377RepeatNote=26 residues 1
P27816217625352377RepeatNote=26 residues 1
P27816217625352377RepeatNote=26 residues 1
P27816217625378403RepeatNote=26 residues 2
P27816217625378403RepeatNote=26 residues 2
P27816217625378403RepeatNote=26 residues 2
P27816217625408421RepeatNote=9
P27816217625408421RepeatNote=9
P27816217625408421RepeatNote=9
P27816217625422433RepeatNote=10
P27816217625422433RepeatNote=10
P27816217625422433RepeatNote=10
P27816217625434447RepeatNote=11
P27816217625434447RepeatNote=11
P27816217625434447RepeatNote=11
P27816217625448461RepeatNote=12
P27816217625448461RepeatNote=12
P27816217625448461RepeatNote=12
P27816217625462475RepeatNote=13
P27816217625462475RepeatNote=13
P27816217625462475RepeatNote=13
P27816217625476489RepeatNote=14
P27816217625476489RepeatNote=14
P27816217625476489RepeatNote=14
P27816217625490503RepeatNote=15
P27816217625490503RepeatNote=15
P27816217625490503RepeatNote=15
P27816217625504517RepeatNote=16
P27816217625504517RepeatNote=16
P27816217625504517RepeatNote=16
P27816217625532545RepeatNote=17
P27816217625532545RepeatNote=17
P27816217625532545RepeatNote=17
P27816217625319319Sequence conflictNote=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305
P27816217625319319Sequence conflictNote=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305
P27816217625319319Sequence conflictNote=D->G;Ontology_term=ECO:0000305;evidence=ECO:0000305
P278166256661001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816625666275666Alternative sequenceID=VSP_032070;Note=In isoform 4. AKDMESPTKLDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPST
P27816625666322666Alternative sequenceID=VSP_032071;Note=In isoform 5. WPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVA
P27816625666441631Alternative sequenceID=VSP_032072;Note=In isoform 3. ETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGT->TEEAVLNQAPQQKKAVRRALSECSHLSVP
P27816625666558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816625666635666Alternative sequenceID=VSP_032073;Note=In isoform 3. CSLPAEEDSVLEKLGERKPCNSQPSELSSETS->EIEVTATQSTPSFLFEKPPRD;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781662566621152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816625666636636Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163,ECO:0000244|PubMed:24275569;Dbxref=PMID:1
P27816625666643643Modified residueNote=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P27546
P27816625666628628Natural variantID=VAR_039570;Note=V->I;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000269;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000269|PubMed:1718985;Dbxref=dbSNP:rs1137524,PMID:18669648,PMID:20068231,PMID:1718985
P278167027741001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816702774558730Alternative sequenceID=VSP_003200;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P27816702774703716Alternative sequenceID=VSP_032074;Note=In isoform 3. PLATTQPAKTSTSK->VGARMVVIFYCHNF;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278167027747171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781670277421152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816702774713713Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P27816702774723723Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P278168358551001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278168358557171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781683585521152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816835855838838Cross-linkNote=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2);Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:28112733;Dbxref=PMID:28112733
P27816835855853853Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P278169539911001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P278169539917171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P27816953991939953Alternative sequenceID=VSP_032076;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P278169539919541022Alternative sequenceID=VSP_032077;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:17974005;Dbxref=PMID:17974005
P2781695399121152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816953991923953RepeatNote=Tau/MAP 1
P2781699110221001152Alternative sequenceID=VSP_043241;Note=In isoform 7. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334
P2781699110227171152Alternative sequenceID=VSP_032075;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039
P2781699110229541022Alternative sequenceID=VSP_032077;Note=In isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:17974005;Dbxref=PMID:17974005
P27816991102221152ChainID=PRO_0000072751;Note=Microtubule-associated protein 4
P27816991102210001000Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:24275569;Dbxref=PMID:21406692,PMID:24275569
P278169911022994994Natural variantID=VAR_039571;Note=I->V;Dbxref=dbSNP:rs35736893
P2781699110229921022RepeatNote=Tau/MAP 2


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SNVs in the skipped exons for MAP4

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.
MAP4_BRCA_exon_skip_383334_psi_boxplot.png
boxplot
MAP4_LUAD_exon_skip_383334_psi_boxplot.png
boxplot
MAP4_LUAD_exon_skip_383359_psi_boxplot.png
boxplot

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A39Y-01exon_skip_383303
exon_skip_383301
47908736479088284790880847908808Frame_Shift_DelT-p.K2143fs
LUSCTCGA-22-4613-01exon_skip_383314
47910704479108174791073347910733Frame_Shift_DelC-p.A982fs
LIHCTCGA-DD-A1EG-01exon_skip_383318
47912717479127764791272847912728Frame_Shift_DelT-p.K1997fs
LIHCTCGA-DD-A3A0-01exon_skip_383334
47950528479539114795069147950691Frame_Shift_DelT-p.K1757fs
LIHCTCGA-DD-A3A0-01exon_skip_383334
47950528479539114795152047951520Frame_Shift_DelT-p.N1481fs
LIHCTCGA-DD-A1EG-01exon_skip_383336
47956307479564294795635847956358Frame_Shift_DelC-p.E667fs
LIHCTCGA-DD-A3A0-01exon_skip_383336
47956307479564294795636547956365Frame_Shift_DelT-p.K664fs
LIHCTCGA-DD-A39Y-01exon_skip_383336
47956307479564294795640547956405Frame_Shift_DelT-p.K651fs
LIHCTCGA-DD-A39Y-01exon_skip_383359
47957441479586644795789647957896Frame_Shift_DelG-p.P491fs
LIHCTCGA-DD-A39Y-01exon_skip_383368
exon_skip_383367
47960209479603314796027447960274Frame_Shift_DelT-p.N213fs
LIHCTCGA-DD-A3A0-01exon_skip_383386
48040128480403694804015648040156Frame_Shift_DelT-p.K65fs
LIHCTCGA-DD-A39Y-01exon_skip_383386
48040128480403694804032248040322Frame_Shift_DelA-p.L10fs
UCECTCGA-BG-A0M0-01exon_skip_383314
47910704479108174791079847910799Frame_Shift_Ins-Tp.T960fs
LIHCTCGA-BC-A112-01exon_skip_383318
47912717479127764791275647912757Frame_Shift_Ins-Tp.NC1987fs
COADTCGA-AA-3713-01exon_skip_383303
exon_skip_383301
47908736479088284790880847908808Nonsense_MutationT-p.V999X
LIHCTCGA-2Y-A9H9-01exon_skip_383314
47910704479108174791077847910778Nonsense_MutationGAp.R967X
BLCATCGA-DK-A6AW-01exon_skip_383334
47950528479539114795074747950747Nonsense_MutationGAp.R1739*
BRCATCGA-E2-A152-01exon_skip_383334
47950528479539114795125447951254Nonsense_MutationCAp.E160*
LUADTCGA-55-7994-01exon_skip_383334
47950528479539114795134447951344Nonsense_MutationCAp.G1540*
LUADTCGA-05-4395-01exon_skip_383359
47957441479586644795747047957470Nonsense_MutationGCp.S616*
LUADTCGA-05-4395-01exon_skip_383359
47957441479586644795747047957470Nonsense_MutationGCp.S633*
UCECTCGA-D1-A103-01exon_skip_383359
47957441479586644795782247957822Nonsense_MutationCAp.E499*
BLCATCGA-XF-A9SY-01exon_skip_383368
exon_skip_383367
47960209479603314796022147960221Nonsense_MutationGAp.Q231*
LUADTCGA-44-7669-01exon_skip_383368
exon_skip_383367
47960209479603314796023047960230Nonsense_MutationCAp.E228*
BLCATCGA-HQ-A5NE-01exon_skip_383386
48040128480403694804014848040148Nonsense_MutationGCp.S68*
UCECTCGA-B5-A0JY-01exon_skip_383386
48040128480403694804023348040233Nonsense_MutationCAp.E40*
UCECTCGA-B5-A0JN-01exon_skip_383303
exon_skip_383301
47908736479088284790873547908735Splice_SiteCTe14+1
UCECTCGA-B5-A0JN-01exon_skip_383303
exon_skip_383301
47908736479088284790873547908735Splice_SiteCTp.N1022_splice
UCECTCGA-BK-A0C9-01exon_skip_383324
47917175479173904791717447917174Splice_SiteCTp.K774_splice
LUADTCGA-75-6214-01exon_skip_383336
47956307479564294795643047956430Splice_SiteCGp.E626_splice

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description
MAP4_47958359_47958664_47960208_47960331_47969717_47969792_TCGA-44-7669-01Sample: TCGA-44-7669-01
Cancer type: LUAD
ESID: exon_skip_383367
Skipped exon start: 47960209
Skipped exon end: 47960331
Mutation start: 47960230
Mutation end: 47960230
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: A
AAchange: p.E228*
exon_skip_383368_LUAD_TCGA-44-7669-01.png
boxplot
exon_skip_423828_LUAD_TCGA-44-7669-01.png
boxplot
MAP4_47956306_47956429_47957440_47958664_47960208_47960241_TCGA-05-4395-01Sample: TCGA-05-4395-01
Cancer type: LUAD
ESID: exon_skip_383359
Skipped exon start: 47957441
Skipped exon end: 47958664
Mutation start: 47957470
Mutation end: 47957470
Mutation type: Nonsense_Mutation
Reference seq: G
Mutation seq: C
AAchange: p.S633*
MAP4_47956306_47956429_47957440_47958664_47960208_47960241_TCGA-05-4395-01Sample: TCGA-05-4395-01
Cancer type: LUAD
ESID: exon_skip_383359
Skipped exon start: 47957441
Skipped exon end: 47958664
Mutation start: 47957470
Mutation end: 47957470
Mutation type: Nonsense_Mutation
Reference seq: G
Mutation seq: C
AAchange: p.S616*
exon_skip_383359_LUAD_TCGA-05-4395-01.png
boxplot
MAP4_47918906_47919013_47950527_47953911_47956306_47956429_TCGA-E2-A152-01Sample: TCGA-E2-A152-01
Cancer type: BRCA
ESID: exon_skip_383334
Skipped exon start: 47950528
Skipped exon end: 47953911
Mutation start: 47951254
Mutation end: 47951254
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: A
AAchange: p.E160*
exon_skip_383334_BRCA_TCGA-E2-A152-01.png
boxplot
MAP4_47918906_47919013_47950527_47953911_47956306_47956429_TCGA-55-7994-01Sample: TCGA-55-7994-01
Cancer type: LUAD
ESID: exon_skip_383334
Skipped exon start: 47950528
Skipped exon end: 47953911
Mutation start: 47951344
Mutation end: 47951344
Mutation type: Nonsense_Mutation
Reference seq: C
Mutation seq: A
AAchange: p.G1540*
exon_skip_383334_LUAD_TCGA-55-7994-01.png
boxplot
MAP4_47898920_47899002_47908735_47908828_47910703_47910817_TCGA-B5-A0JN-01Sample: TCGA-B5-A0JN-01
Cancer type: UCEC
ESID: exon_skip_383301
Skipped exon start: 47908736
Skipped exon end: 47908828
Mutation start: 47908735
Mutation end: 47908735
Mutation type: Splice_Site
Reference seq: C
Mutation seq: T
AAchange: p.N1022_splice
MAP4_47898920_47899002_47908735_47908828_47910703_47910817_TCGA-B5-A0JN-01Sample: TCGA-B5-A0JN-01
Cancer type: UCEC
ESID: exon_skip_383301
Skipped exon start: 47908736
Skipped exon end: 47908828
Mutation start: 47908735
Mutation end: 47908735
Mutation type: Splice_Site
Reference seq: C
Mutation seq: T
AAchange: e14+1
exon_skip_383301_UCEC_TCGA-B5-A0JN-01.png
boxplot
exon_skip_77675_UCEC_TCGA-B5-A0JN-01.png
boxplot

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
EN_ENDOMETRIUM47910704479108174791079947910799Frame_Shift_DelT-p.T960fs
MFE319_ENDOMETRIUM47956307479564294795635847956358Frame_Shift_DelC-p.E650fs
JHH1_LIVER47917175479173904791726147917262Frame_Shift_Ins-TGAAp.G746fs
SNU1040_LARGE_INTESTINE47894653478948424789467047894670Missense_MutationCTp.S1145N
BICR18_UPPER_AERODIGESTIVE_TRACT47894653478948424789468647894686Missense_MutationCGp.A1140P
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789468647894686Missense_MutationCGp.A1140P
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789468647894686Missense_MutationCGp.A1140P
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789469847894698Missense_MutationCTp.D1136N
BICR18_UPPER_AERODIGESTIVE_TRACT47894653478948424789471947894719Missense_MutationGTp.P1129T
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789471947894719Missense_MutationGTp.P1129T
OVK18_OVARY47894653478948424789472247894722Missense_MutationGTp.H1128N
BICR18_UPPER_AERODIGESTIVE_TRACT47894653478948424789472747894727Missense_MutationTCp.N1126S
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789472747894727Missense_MutationTCp.N1126S
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789472747894727Missense_MutationTCp.N1126S
HEC50B_ENDOMETRIUM47894653478948424789474847894748Missense_MutationGAp.P1119L
KARPAS231_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47894653478948424789480847894808Missense_MutationGCp.P1099R
EOL1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47908736479088284790874147908741Missense_MutationCGp.G1021R
MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47917175479173904791722247917222Missense_MutationCTp.A759T
SNU175_LARGE_INTESTINE47917175479173904791727047917270Missense_MutationGAp.L743F
BICR18_UPPER_AERODIGESTIVE_TRACT47917175479173904791729947917300Missense_MutationATGAp.I733S
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47917175479173904791729947917300Missense_MutationATGAp.I733S
BICR18_UPPER_AERODIGESTIVE_TRACT47917175479173904791729947917299Missense_MutationAGp.I733T
BICR18_UPPER_AERODIGESTIVE_TRACT47917175479173904791730047917300Missense_MutationTAp.I733F
PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47917175479173904791738147917381Missense_MutationTCp.T706A
HT1197_URINARY_TRACT47956307479564294795630947956309Missense_MutationGAp.S666L
GA10_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47956307479564294795632747956327Missense_MutationTAp.E660V
IALM_LUNG47957441479586644795751247957512Missense_MutationCTp.S602N
EN_ENDOMETRIUM47957441479586644795753947957539Missense_MutationTCp.E593G
KATOIII_STOMACH47957441479586644795763547957635Missense_MutationTCp.D561G
TCCSUP_URINARY_TRACT47957441479586644795771447957714Missense_MutationACp.C535G
ESS1_ENDOMETRIUM47957441479586644795772947957729Missense_MutationGTp.L530I
HT1197_URINARY_TRACT47957441479586644795783747957837Missense_MutationGAp.P494S
MDAMB435S_SKIN47957441479586644795787347957873Missense_MutationGAp.P482S
NCIH2135_LUNG47957441479586644795793747957937Missense_MutationCAp.L460F
JHH1_LIVER47957441479586644795797847957978Missense_MutationCAp.A447S
MCC13_SKIN47957441479586644795813947958139Missense_MutationGAp.S393F
IGR1_SKIN47957441479586644795816347958163Missense_MutationGAp.P385L
HCT15_LARGE_INTESTINE47957441479586644795838847958388Missense_MutationGAp.T310I
EFO27_OVARY47957441479586644795839147958391Missense_MutationGTp.P309H
DND41_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE47957441479586644795857447958574Missense_MutationGAp.T248I
NCIH1876_LUNG47960209479603314796032547960325Missense_MutationGAp.S179F
SW684_SOFT_TISSUE47960209479603314796032547960325Missense_MutationGAp.S179F
YAMATO_SOFT_TISSUE47963255479633684796331147963311Missense_MutationGAp.A158V
SNU1040_LARGE_INTESTINE47963255479633684796331247963312Missense_MutationCTp.A158T
GT3TKB_STOMACH47963255479633684796331547963315Missense_MutationTAp.S157C
RERFLCAI_LUNG47963255479633684796331547963315Missense_MutationTAp.S157C
SNU1040_LARGE_INTESTINE47963255479633684796335347963353Missense_MutationTCp.Y144C
NCIH1573_LUNG48040128480403694804017948040179Missense_MutationCAp.G58W
KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48040128480403694804021548040215Missense_MutationCTp.D46N
JHUEM7_ENDOMETRIUM48040128480403694804023848040238Missense_MutationAGp.V38A
KMS26_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48040128480403694804031348040313Missense_MutationGAp.P13L
RPMI8402_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE48040128480403694804033248040332Missense_MutationCAp.A7S
UMUC14_URINARY_TRACT47957441479586644795832847958328Nonsense_MutationGTp.S330*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MAP4

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_383359347956306:47956429:47957440:47958664:47960208:4796024147957440:47958664ENST00000426837.2,ENST00000360240.6,ENST00000395734.3OVrs1060407chr3:47958037G/T5.37e-04
exon_skip_383336347918906:47919013:47956306:47956429:47957440:4795803147956306:47956429ENST00000360240.6,ENST00000395734.3BRCArs1137524chr3:47956424C/T2.91e-03
exon_skip_383336347918906:47919013:47956306:47956429:47957440:4795803147956306:47956429ENST00000360240.6,ENST00000395734.3STADrs1137524chr3:47956424C/T1.10e-03
exon_skip_383336347918906:47919013:47956306:47956429:47957440:4795803147956306:47956429ENST00000360240.6,ENST00000395734.3STADrs1137524chr3:47956424C/T1.11e-03
exon_skip_383334347918906:47919013:47950527:47953911:47956306:4795642947950527:47953911ENST00000426837.2OVrs34025851chr3:47953733C/A1.21e-03
exon_skip_383334347918906:47919013:47950527:47953911:47956306:4795642947950527:47953911ENST00000426837.2OVrs4858871chr3:47953405A/C1.53e-03
exon_skip_383334347918906:47919013:47950527:47953911:47956306:4795642947950527:47953911ENST00000426837.2STADrs4858871chr3:47953405A/C1.69e-03
exon_skip_383334347918906:47919013:47950527:47953911:47956306:4795642947950527:47953911ENST00000426837.2STADrs4858871chr3:47953405A/C1.70e-03

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MAP4


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MAP4


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RelatedDrugs for MAP4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
P27816DB01248DocetaxelMicrotubule-associated protein 4small moleculeapproved|investigational
P27816DB01229PaclitaxelMicrotubule-associated protein 4small moleculeapproved|vet_approved

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RelatedDiseases for MAP4

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
MAP4C0043094Weight Gain1CTD_human