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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for GOLGA4

check button Gene summary
Gene informationGene symbol

GOLGA4

Gene ID

2803

Gene namegolgin A4
SynonymsCRPF46|GCP2|GOLG|MU-RMS-40.18|p230
Cytomap

3p22.2

Type of geneprotein-coding
Descriptiongolgin subfamily A member 4256 kDa golgin72.1 proteincentrosome-related protein F46golgi autoantigen, golgin subfamily a, 4golgin-240golgin-245protein 72.1trans-Golgi p230
Modification date20180519
UniProtAcc

Q13439

ContextPubMed: GOLGA4 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
GOLGA4

GO:0043001

Golgi to plasma membrane protein transport

15265687

GOLGA4

GO:0045773

positive regulation of axon extension

22705394


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Exon skipping events across known transcript of Ensembl for GOLGA4 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for GOLGA4

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for GOLGA4

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_372677337284914:37285113:37292885:37292975:37315026:3731509237292885:37292975ENSG00000144674.12ENST00000450863.2,ENST00000356847.4,ENST00000429018.1
exon_skip_372678337284914:37285113:37292885:37292975:37323448:3732347637292885:37292975ENSG00000144674.12ENST00000444882.1,ENST00000419177.3
exon_skip_372681337292885:37292975:37308332:37308431:37315026:3731509237308332:37308431ENSG00000144674.12ENST00000431105.1
exon_skip_372683337292885:37292975:37315026:37315092:37323448:3732347637315026:37315092ENSG00000144674.12ENST00000450863.2,ENST00000356847.4
exon_skip_372688337292885:37292975:37323448:37323763:37327504:3732755237323448:37323763ENSG00000144674.12ENST00000361924.2
exon_skip_372689337292885:37292975:37323448:37323763:37330725:3733078237323448:37323763ENSG00000144674.12ENST00000419177.3
exon_skip_372695337315026:37315092:37323448:37323763:37327504:3732755237323448:37323763ENSG00000144674.12ENST00000356847.4
exon_skip_372696337315026:37315092:37323448:37323763:37330725:3733078237323448:37323763ENSG00000144674.12ENST00000450863.2
exon_skip_372698337323673:37323763:37327504:37327552:37330725:3733078237327504:37327552ENSG00000144674.12ENST00000361924.2,ENST00000437131.1,ENST00000356847.4
exon_skip_372701337323673:37323763:37330725:37330782:37336469:3733656837330725:37330782ENSG00000144674.12ENST00000419177.3
exon_skip_372703337327504:37327552:37329017:37329103:37330725:3733078237329017:37329103ENSG00000144674.12ENST00000435830.2
exon_skip_372705337327504:37327552:37330725:37330782:37336469:3733656837330725:37330782ENSG00000144674.12ENST00000361924.2,ENST00000437131.1,ENST00000356847.4
exon_skip_372706337340323:37340511:37340778:37340862:37343675:3734382337340778:37340862ENSG00000144674.12ENST00000435830.2,ENST00000361924.2,ENST00000437131.1,ENST00000450863.2,ENST00000356847.4
exon_skip_372707337343691:37343823:37354912:37355010:37356910:3735699737354912:37355010ENSG00000144674.12ENST00000435830.2
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENSG00000144674.12ENST00000361924.2,ENST00000437131.1,ENST00000356847.4
exon_skip_372724337369906:37370028:37370453:37370584:37376543:3737665737370453:37370584ENSG00000144674.12ENST00000361924.2,ENST00000437131.1,ENST00000356847.4
exon_skip_372728337376543:37376657:37378633:37378654:37379156:3737922537378633:37378654ENSG00000144674.12ENST00000361924.2,ENST00000437131.1
exon_skip_372733337376543:37376657:37379156:37379225:37381614:3738169037379156:37379225ENSG00000144674.12ENST00000356847.4
exon_skip_372737337378633:37378654:37379156:37379225:37381614:3738169037379156:37379225ENSG00000144674.12ENST00000361924.2,ENST00000437131.1
exon_skip_372741337381614:37381690:37388683:37388787:37396591:3739667837388683:37388787ENSG00000144674.12ENST00000361924.2,ENST00000437131.1,ENST00000356847.4
exon_skip_372742337396591:37396678:37402733:37402796:37407570:3740823637402733:37402796ENSG00000144674.12ENST00000361924.2

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for GOLGA4

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_372677337284914:37285113:37292885:37292975:37315026:3731509237292885:37292975ENSG00000144674.12ENST00000356847.4,ENST00000450863.2,ENST00000429018.1
exon_skip_372678337284914:37285113:37292885:37292975:37323448:3732347637292885:37292975ENSG00000144674.12ENST00000444882.1,ENST00000419177.3
exon_skip_372681337292885:37292975:37308332:37308431:37315026:3731509237308332:37308431ENSG00000144674.12ENST00000431105.1
exon_skip_372683337292885:37292975:37315026:37315092:37323448:3732347637315026:37315092ENSG00000144674.12ENST00000356847.4,ENST00000450863.2
exon_skip_372688337292885:37292975:37323448:37323763:37327504:3732755237323448:37323763ENSG00000144674.12ENST00000361924.2
exon_skip_372689337292885:37292975:37323448:37323763:37330725:3733078237323448:37323763ENSG00000144674.12ENST00000419177.3
exon_skip_372695337315026:37315092:37323448:37323763:37327504:3732755237323448:37323763ENSG00000144674.12ENST00000356847.4
exon_skip_372696337315026:37315092:37323448:37323763:37330725:3733078237323448:37323763ENSG00000144674.12ENST00000450863.2
exon_skip_372698337323673:37323763:37327504:37327552:37330725:3733078237327504:37327552ENSG00000144674.12ENST00000361924.2,ENST00000356847.4,ENST00000437131.1
exon_skip_372701337323673:37323763:37330725:37330782:37336469:3733656837330725:37330782ENSG00000144674.12ENST00000419177.3
exon_skip_372703337327504:37327552:37329017:37329103:37330725:3733078237329017:37329103ENSG00000144674.12ENST00000435830.2
exon_skip_372705337327504:37327552:37330725:37330782:37336469:3733656837330725:37330782ENSG00000144674.12ENST00000361924.2,ENST00000356847.4,ENST00000437131.1
exon_skip_372706337340323:37340511:37340778:37340862:37343675:3734382337340778:37340862ENSG00000144674.12ENST00000361924.2,ENST00000435830.2,ENST00000356847.4,ENST00000450863.2,ENST00000437131.1
exon_skip_372707337343691:37343823:37354912:37355010:37356910:3735699737354912:37355010ENSG00000144674.12ENST00000435830.2
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENSG00000144674.12ENST00000361924.2,ENST00000356847.4,ENST00000437131.1
exon_skip_372724337369906:37370028:37370453:37370584:37376543:3737665737370453:37370584ENSG00000144674.12ENST00000361924.2,ENST00000356847.4,ENST00000437131.1
exon_skip_372728337376543:37376657:37378633:37378654:37379156:3737922537378633:37378654ENSG00000144674.12ENST00000361924.2,ENST00000437131.1
exon_skip_372733337376543:37376657:37379156:37379225:37381614:3738169037379156:37379225ENSG00000144674.12ENST00000356847.4
exon_skip_372737337378633:37378654:37379156:37379225:37381614:3738169037379156:37379225ENSG00000144674.12ENST00000361924.2,ENST00000437131.1
exon_skip_372741337381614:37381690:37388683:37388787:37396591:3739667837388683:37388787ENSG00000144674.12ENST00000361924.2,ENST00000356847.4,ENST00000437131.1
exon_skip_372742337396591:37396678:37402733:37402796:37407570:3740823637402733:37402796ENSG00000144674.12ENST00000361924.2

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for GOLGA4

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000036192437402733374027963UTR-3CDS
ENST000003619243736507837369316Frame-shift
ENST000003619243737045337370584Frame-shift
ENST000003619243738868337388787Frame-shift
ENST000003619243732344837323763In-frame
ENST000003619243732750437327552In-frame
ENST000003619243733072537330782In-frame
ENST000003619243734077837340862In-frame
ENST000003619243737863337378654In-frame
ENST000003619243737915637379225In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000036192437402733374027963UTR-3CDS
ENST000003619243736507837369316Frame-shift
ENST000003619243737045337370584Frame-shift
ENST000003619243738868337388787Frame-shift
ENST000003619243732344837323763In-frame
ENST000003619243732750437327552In-frame
ENST000003619243733072537330782In-frame
ENST000003619243734077837340862In-frame
ENST000003619243737863337378654In-frame
ENST000003619243737915637379225In-frame

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Infer the effects of exon skipping event on protein functional features for GOLGA4

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000036192477892230373234483732376353785154159
ENST00000361924778922303732750437327552852899159175
ENST00000361924778922303733072537330782900956175194
ENST0000036192477892230373407783734086213771460334362
ENST000003619247789223037379156373792256702677021092132

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST0000036192477892230373234483732376353785154159
ENST00000361924778922303732750437327552852899159175
ENST00000361924778922303733072537330782900956175194
ENST0000036192477892230373407783734086213771460334362
ENST000003619247789223037379156373792256702677021092132

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q13439541595454Alternative sequenceID=VSP_044819;Note=In isoform 5. E->ENASTHASKSPDSVNGSEPSIPQ;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4
Q134395415912230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q13439541591332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q13439541597171Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:20068231,PMID:21406692,PMID
Q13439541597878Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
Q13439541598989Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q1343954159133203RegionNote=Interaction with MACF1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15265687;Dbxref=PMID:15265687
Q1343915917512230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q134391591751332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q13439159175133203RegionNote=Interaction with MACF1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15265687;Dbxref=PMID:15265687
Q1343917519412230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q134391751941332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q13439175194133203RegionNote=Interaction with MACF1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15265687;Dbxref=PMID:15265687
Q13439175194188188Sequence conflictNote=R->K;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q1343933436212230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q134393343621332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q134393343622522096Compositional biasNote=Glu-rich
Q134392109213221032109Alternative sequenceID=VSP_004274;Note=In isoform 3 and isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4
Q134392109213212230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q13439210921321332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q13439541595454Alternative sequenceID=VSP_044819;Note=In isoform 5. E->ENASTHASKSPDSVNGSEPSIPQ;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4
Q134395415912230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q13439541591332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q13439541597171Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:18669648,ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:21406692,ECO:0000244|PubMed:23186163;Dbxref=PMID:18669648,PMID:20068231,PMID:21406692,PMID
Q13439541597878Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244,ECO:0000244;evidence=ECO:0000244|PubMed:20068231,ECO:0000244|PubMed:23186163;Dbxref=PMID:20068231,PMID:23186163
Q13439541598989Modified residueNote=Phosphoserine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:18669648;Dbxref=PMID:18669648
Q1343954159133203RegionNote=Interaction with MACF1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15265687;Dbxref=PMID:15265687
Q1343915917512230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q134391591751332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q13439159175133203RegionNote=Interaction with MACF1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15265687;Dbxref=PMID:15265687
Q1343917519412230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q134391751941332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q13439175194133203RegionNote=Interaction with MACF1;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15265687;Dbxref=PMID:15265687
Q13439175194188188Sequence conflictNote=R->K;Ontology_term=ECO:0000305;evidence=ECO:0000305
Q1343933436212230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q134393343621332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255
Q134393343622522096Compositional biasNote=Glu-rich
Q134392109213221032109Alternative sequenceID=VSP_004274;Note=In isoform 3 and isoform 5. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.4
Q134392109213212230ChainID=PRO_0000190059;Note=Golgin subfamily A member 4
Q13439210921321332185Coiled coilOntology_term=ECO:0000255;evidence=ECO:0000255


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SNVs in the skipped exons for GOLGA4

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A39Y-01exon_skip_372677
exon_skip_372678
37292886372929753729293737292937Frame_Shift_DelT-p.F42fs
STADTCGA-BR-8591-01exon_skip_372689
exon_skip_372688
exon_skip_372695
exon_skip_372696
37323449373237633732375137323751Frame_Shift_DelA-p.G155fs
STADTCGA-BR-8591-01exon_skip_372689
exon_skip_372688
exon_skip_372695
exon_skip_372696
37323449373237633732375137323751Frame_Shift_DelA-p.G177fs
LIHCTCGA-DD-A3A0-01exon_skip_372706
37340779373408623734082937340829Frame_Shift_DelA-p.A351fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736510737365107Frame_Shift_DelA-p.E577fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736510737365107Frame_Shift_DelA-p.E577fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736516737365167Frame_Shift_DelA-p.E597fs
UCECTCGA-AP-A05N-01exon_skip_372718
37365079373693163736516737365167Frame_Shift_DelA-p.E597fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736520637365206Frame_Shift_DelA-p.E610fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736526337365263Frame_Shift_DelA-p.E629fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736530537365305Frame_Shift_DelA-p.E643fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736571637365716Frame_Shift_DelA-p.E780fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736581937365819Frame_Shift_DelA-p.T814fs
SKCMTCGA-EE-A3JI-06exon_skip_372718
37365079373693163736587637365877Frame_Shift_DelAG-p.833_833del
SKCMTCGA-EE-A3JI-06exon_skip_372718
37365079373693163736587637365877Frame_Shift_DelAG-p.TE833fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736623537366235Frame_Shift_DelA-p.E953fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736624737366247Frame_Shift_DelA-p.E957fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736629137366291Frame_Shift_DelA-p.K973fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736636437366364Frame_Shift_DelA-p.E996fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736678737366787Frame_Shift_DelA-p.E1137fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736695537366955Frame_Shift_DelA-p.E1193fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736695537366955Frame_Shift_DelA-p.E1215fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736699637366996Frame_Shift_DelA-p.K1208fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736706837367068Frame_Shift_DelA-p.K1231fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736711737367117Frame_Shift_DelT-p.L1247fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736717637367176Frame_Shift_DelA-p.K1267fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736727937367279Frame_Shift_DelA-p.E1301fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736754937367549Frame_Shift_DelA-p.E1391fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736759437367594Frame_Shift_DelA-p.E1406fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736763137367631Frame_Shift_DelT-p.S1418fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736831437368314Frame_Shift_DelA-p.Q1646fs
UCECTCGA-D1-A17F-01exon_skip_372718
37365079373693163736831437368314Frame_Shift_DelA-p.Q1646fs
KIRPTCGA-UZ-A9PO-01exon_skip_372718
37365079373693163736846037368460Frame_Shift_DelC-p.K1716fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736861737368617Frame_Shift_DelA-p.E1747fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736865037368650Frame_Shift_DelA-p.E1758fs
LIHCTCGA-DD-A3A0-01exon_skip_372718
37365079373693163736865037368650Frame_Shift_DelA-p.E1758fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736866537368665Frame_Shift_DelT-p.V1763fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736867537368675Frame_Shift_DelT-p.H1766fs
LIHCTCGA-G3-A3CJ-01exon_skip_372718
37365079373693163736878537368785Frame_Shift_DelA-p.E1803fs
LIHCTCGA-DD-A39Y-01exon_skip_372718
37365079373693163736905637369056Frame_Shift_DelA-p.R1893fs
LIHCTCGA-DD-A1EG-01exon_skip_372718
37365079373693163736906037369060Frame_Shift_DelA-p.K1895fs
BLCATCGA-UY-A9PD-01exon_skip_372718
37365079373693163736917737369177Frame_Shift_DelG-p.G1934fs
LIHCTCGA-DD-A39Y-01exon_skip_372741
37388684373887873738874837388748Frame_Shift_DelA-p.R2179fs
STADTCGA-D7-6818-01exon_skip_372718
37365079373693163736510637365107Frame_Shift_Ins-Ap.E599fs
STADTCGA-D7-6818-01exon_skip_372718
37365079373693163736510737365108Frame_Shift_Ins-Ap.E577fs
LIHCTCGA-BC-A112-01exon_skip_372718
37365079373693163736516637365167Frame_Shift_Ins-Ap.K597fs
TGCTTCGA-2G-AAGI-01exon_skip_372718
37365079373693163736746737367468Frame_Shift_Ins-Ap.K1364fs
LIHCTCGA-BC-A112-01exon_skip_372718
37365079373693163736878437368785Frame_Shift_Ins-Ap.K1803fs
KIRPTCGA-UZ-A9PX-01exon_skip_372718
37365079373693163736905537369056Frame_Shift_Ins-AAATp.R1915fs
BLCATCGA-DK-AA74-01exon_skip_372718
37365079373693163736513737365137Nonsense_MutationCGp.S587*
READTCGA-F5-6814-01exon_skip_372718
37365079373693163736533737365337Nonsense_MutationGTp.E676X
LUADTCGA-55-8507-01exon_skip_372718
37365079373693163736545137365451Nonsense_MutationGTp.E692*
LUSCTCGA-39-5036-01exon_skip_372718
37365079373693163736607237366072Nonsense_MutationCTp.Q899*
SKCMTCGA-EE-A2GJ-06exon_skip_372718
37365079373693163736630637366306Nonsense_MutationCTp.Q977*
LUADTCGA-78-7539-01exon_skip_372718
37365079373693163736752737367527Nonsense_MutationCTp.Q1384*
BRCATCGA-BH-A0DZ-01exon_skip_372718
37365079373693163736784837367848Nonsense_MutationCTp.Q1491*
COADTCGA-AZ-4315-01exon_skip_372718
37365079373693163736805837368058Nonsense_MutationGTp.E1583X
READTCGA-AG-A002-01exon_skip_372718
37365079373693163736805837368058Nonsense_MutationGTp.E1583X
READTCGA-F5-6814-01exon_skip_372718
37365079373693163736805837368058Nonsense_MutationGTp.E1583X
UCSTCGA-ND-A4WC-01exon_skip_372718
37365079373693163736805837368058Nonsense_MutationGTp.E1561*
UCSTCGA-ND-A4WC-01exon_skip_372718
37365079373693163736805837368058Nonsense_MutationGTp.E1583X
COADTCGA-AA-3489-01exon_skip_372718
37365079373693163736808537368085Nonsense_MutationCTp.Q1592X
COADTCGA-CA-6717-01exon_skip_372718
37365079373693163736819637368196Nonsense_MutationGTp.E1629X
BLCATCGA-GC-A6I3-01exon_skip_372718
37365079373693163736826937368269Nonsense_MutationCGp.S1631*
BRCATCGA-BH-A0DZ-01exon_skip_372718
37365079373693163736848537368485Nonsense_MutationCGp.S1703*
THYMTCGA-X7-A8DC-01exon_skip_372718
37365079373693163736882637368826Nonsense_MutationGTp.E1839X
GBMTCGA-06-0192-01exon_skip_372718
37365079373693163736903737369037Nonsense_MutationTGp.L1887*
SKCMTCGA-EE-A3AE-06exon_skip_372733
exon_skip_372737
37379157373792253737916937379169Nonsense_MutationCTp.Q2114*
KIRPTCGA-P4-A5EA-01exon_skip_372718
37365079373693163736507737365078Splice_SiteAG-.
KIRPTCGA-P4-A5EA-01exon_skip_372718
37365079373693163736507737365078Splice_SiteAG-p.R568_splice
ACCTCGA-OR-A5K2-01exon_skip_372741
37388684373887873738868237388682Splice_SiteAT.

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
22RV1_PROSTATE37365079373693163736510737365107Frame_Shift_DelA-p.E577fs
EN_ENDOMETRIUM37365079373693163736578237365782Frame_Shift_DelT-p.V802fs
SNUC2A_LARGE_INTESTINE37365079373693163736746837367468Frame_Shift_DelA-p.E1364fs
SNUC2B_LARGE_INTESTINE37365079373693163736746837367468Frame_Shift_DelA-p.E1364fs
ANGMCSS_CENTRAL_NERVOUS_SYSTEM37365079373693163736750837367509Frame_Shift_DelTG-p.D1378fs
SISO_CERVIX37365079373693163736809637368096Frame_Shift_DelA-p.G1573fs
GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736809637368096Frame_Shift_DelA-p.G1573fs
DND41_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736831437368314Frame_Shift_DelA-p.Q1646fs
LNCAPCLONEFGC_PROSTATE37365079373693163736831437368314Frame_Shift_DelA-p.Q1646fs
FARAGE_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736851337368513Frame_Shift_DelA-p.A1712fs
U698M_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736909437369094Frame_Shift_DelA-p.E1906fs
SKUT1_SOFT_TISSUE37370454373705843737051937370519Frame_Shift_DelA-p.K2044fs
CW2_LARGE_INTESTINE37365079373693163736510637365107Frame_Shift_Ins-Ap.E577fs
KU812_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736746737367468Frame_Shift_Ins-Ap.E1364fs
MC116_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736746737367468Frame_Shift_Ins-Ap.E1364fs
SUDHL10_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736831337368314Frame_Shift_Ins-Ap.Q1646fs
BT549_BREAST37365079373693163736878437368785Frame_Shift_Ins-Ap.E1803fs
JMSU1_URINARY_TRACT37365079373693163736878437368785Frame_Shift_Ins-Ap.E1803fs
T173_FIBROBLAST37365079373693163736878437368785Frame_Shift_Ins-Ap.E1803fs
A673_BONE37365079373693163736512437365126In_Frame_DelAAC-p.N583del
NCIH460_LUNG37365079373693163736692437366926In_Frame_DelGAA-p.E1184del
HCT15_LARGE_INTESTINE37292886372929753729293237292932Missense_MutationCAp.S40Y
HT115_LARGE_INTESTINE37323449373237633732351637323516Missense_MutationGAp.R77Q
K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37323449373237633732357937323579Missense_MutationCAp.S98Y
TGBC11TKB_STOMACH37327505373275523732751137327511Missense_MutationACp.T162P
PC14_LUNG37330726373307823733075437330754Missense_MutationCTp.S185L
HCC2998_LARGE_INTESTINE37365079373693163736508137365081Missense_MutationACp.R568S
MEWO_SKIN37365079373693163736510137365101Missense_MutationCTp.S575F
SW1463_LARGE_INTESTINE37365079373693163736519337365193Missense_MutationACp.T606P
LB2241RCC_KIDNEY37365079373693163736527537365275Missense_MutationTCp.V633A
BONNA12_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736540537365405Missense_MutationACp.L676F
HEC108_ENDOMETRIUM37365079373693163736541937365419Missense_MutationTCp.V681A
LB2518MEL_SKIN37365079373693163736549237365493Missense_MutationGGAAp.E706K
KYSE510_OESOPHAGUS37365079373693163736556137365561Missense_MutationGCp.Q728H
LI7_LIVER37365079373693163736556937365569Missense_MutationATp.H731L
MERO95_LUNG37365079373693163736576737365767Missense_MutationCTp.S797F
BCP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736576937365769Missense_MutationGAp.A798T
HT144_SKIN37365079373693163736578137365781Missense_MutationGAp.V802I
L428_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736611337366113Missense_MutationGAp.M912I
A427_LUNG37365079373693163736620237366202Missense_MutationATp.N942I
SNU175_LARGE_INTESTINE37365079373693163736635837366358Missense_MutationAGp.Q994R
UPCISCC152_UPPER_AERODIGESTIVE_TRACT37365079373693163736638237366382Missense_MutationAGp.K1002R
SCC90_UPPER_AERODIGESTIVE_TRACT37365079373693163736638237366382Missense_MutationAGp.K1002R
NCIH1568_LUNG37365079373693163736639537366395Missense_MutationGAp.M1006I
MDAMB330_BREAST37365079373693163736643037366430Missense_MutationTCp.V1018A
NCIH2052_PLEURA37365079373693163736649037366490Missense_MutationGAp.R1038Q
NCIBL2052_MATCHED_NORMAL_TISSUE37365079373693163736649037366490Missense_MutationGAp.R1038Q
HCC2998_LARGE_INTESTINE37365079373693163736656637366566Missense_MutationACp.E1063D
J82_URINARY_TRACT37365079373693163736659737366597Missense_MutationGAp.A1074T
EWS834_BONE37365079373693163736663137366631Missense_MutationGCp.C1085S
ES5_BONE37365079373693163736667837366678Missense_MutationGCp.G1101R
SNU81_LARGE_INTESTINE37365079373693163736681937366819Missense_MutationACp.K1148Q
TTC709_SOFT_TISSUE37365079373693163736687337366873Missense_MutationGAp.E1166K
STM9101_SOFT_TISSUE37365079373693163736687337366873Missense_MutationGAp.E1166K
HCC1438_LUNG37365079373693163736700337367003Missense_MutationTCp.L1209P
HEC151_ENDOMETRIUM37365079373693163736703537367035Missense_MutationTCp.C1220R
WM115_SKIN37365079373693163736707937367079Missense_MutationGTp.E1234D
CTV1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736710437367104Missense_MutationAGp.T1243A
AM38_CENTRAL_NERVOUS_SYSTEM37365079373693163736714937367149Missense_MutationATp.T1258S
MM383_SKIN37365079373693163736722437367224Missense_MutationGAp.E1283K
C4I_CERVIX37365079373693163736722437367224Missense_MutationGCp.E1283Q
HS863T_FIBROBLAST37365079373693163736722537367225Missense_MutationACp.E1283A
TGBC11TKB_STOMACH37365079373693163736724337367243Missense_MutationAGp.N1289S
A172_CENTRAL_NERVOUS_SYSTEM37365079373693163736729837367298Missense_MutationGCp.K1307N
EHEB_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736763537367635Missense_MutationAGp.K1420E
NH12_AUTONOMIC_GANGLIA37365079373693163736765037367650Missense_MutationACp.S1425R
K2_SKIN37365079373693163736794837367948Missense_MutationCTp.T1524I
EN_ENDOMETRIUM37365079373693163736796637367966Missense_MutationTCp.L1530S
SNU81_LARGE_INTESTINE37365079373693163736798537367985Missense_MutationGTp.Q1536H
HLFA_FIBROBLAST37365079373693163736798737367987Missense_MutationAGp.K1537R
HCC2998_LARGE_INTESTINE37365079373693163736798737367987Missense_MutationAGp.K1537R
KE97_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736800037368000Missense_MutationAGp.I1541M
C4I_CERVIX37365079373693163736800137368001Missense_MutationGCp.E1542Q
DV90_LUNG37365079373693163736810637368106Missense_MutationGAp.D1577N
COLO824_BREAST37365079373693163736820937368209Missense_MutationTGp.V1611G
HCC2998_LARGE_INTESTINE37365079373693163736822337368223Missense_MutationAGp.K1616E
MFE319_ENDOMETRIUM37365079373693163736824837368248Missense_MutationCTp.A1624V
NCIH2228_LUNG37365079373693163736825637368256Missense_MutationGAp.D1627N
JHH5_LIVER37365079373693163736847537368475Missense_MutationAGp.S1700G
GA10_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736854137368541Missense_MutationGCp.E1722Q
MHHPREB1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736854737368547Missense_MutationGAp.A1724T
HCC2998_LARGE_INTESTINE37365079373693163736860537368605Missense_MutationGTp.R1743I
HCC2998_LARGE_INTESTINE37365079373693163736879537368795Missense_MutationGTp.K1806N
MCC13_SKIN37365079373693163736880337368803Missense_MutationCTp.S1809F
SNU81_LARGE_INTESTINE37365079373693163736888637368886Missense_MutationGAp.D1837N
OCILY12_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736894437368944Missense_MutationTCp.I1856T
HUTU80_SMALL_INTESTINE37365079373693163736913237369132Missense_MutationAGp.S1919G
HCC1171_LUNG37365079373693163736913937369139Missense_MutationTCp.M1921T
RAJI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736917737369177Missense_MutationGAp.G1934R
MCC142_SKIN37365079373693163736925237369252Missense_MutationGCp.E1959Q
COLO679_SKIN37370454373705843737049637370496Missense_MutationACp.Q2035P
HEC251_ENDOMETRIUM37370454373705843737054137370541Missense_MutationACp.D2050A
EW24_BONE37370454373705843737055237370552Missense_MutationCGp.R2054G
JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37370454373705843737057937370579Missense_MutationCTp.L2063F
NCIH2029_LUNG37388684373887873738871637388716Missense_MutationTAp.F2169I
SNU1040_LARGE_INTESTINE37388684373887873738875537388755Missense_MutationCTp.L2182F
DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37388684373887873738876737388767Missense_MutationAGp.M2186V
COV318_OVARY37323449373237633732356937323569Nonsense_MutationCTp.R95*
HCT15_LARGE_INTESTINE37340779373408623734084537340845Nonsense_MutationCTp.Q357*
NCIH1703_LUNG37365079373693163736579637365796Nonsense_MutationCTp.Q807*
PEER_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37365079373693163736738937367389Nonsense_MutationGTp.E1338*
HEC251_ENDOMETRIUM37365079373693163736745537367455Nonsense_MutationGTp.E1360*
SNU81_LARGE_INTESTINE37365079373693163736776137367761Nonsense_MutationGTp.E1462*
JHUEM7_ENDOMETRIUM37365079373693163736805837368058Nonsense_MutationGTp.E1561*
HT115_LARGE_INTESTINE37365079373693163736819637368196Nonsense_MutationGTp.E1607*
SKUT1_SOFT_TISSUE37370454373705843737055237370552Nonsense_MutationCTp.R2054*
NK92MI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE37292886372929753729288737292887Splice_SiteCTp.A25V

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for GOLGA4

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENST00000361924.2,ENST00000437131.1,ENST00000356847.4LGGrs62241896chr3:37368755T/A4.60e-04
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENST00000361924.2,ENST00000437131.1,ENST00000356847.4LGGrs11718848chr3:37366459C/A5.71e-04
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENST00000361924.2,ENST00000437131.1,ENST00000356847.4PAADrs11718848chr3:37366459C/A2.23e-07
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENST00000361924.2,ENST00000437131.1,ENST00000356847.4PAADrs62241896chr3:37368755T/A2.23e-07
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENST00000361924.2,ENST00000437131.1,ENST00000356847.4SKCMrs11718848chr3:37366459C/A4.69e-05
exon_skip_372718337363221:37363377:37365078:37369316:37369906:3737002837365078:37369316ENST00000361924.2,ENST00000437131.1,ENST00000356847.4SKCMrs62241896chr3:37368755T/A4.69e-05

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for GOLGA4


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for GOLGA4


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RelatedDrugs for GOLGA4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for GOLGA4

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
GOLGA4C0033578Prostatic Neoplasms1CTD_human
GOLGA4C0037274Dermatologic disorders1CTD_human
GOLGA4C0311375Arsenic Poisoning1CTD_human