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Center for Computational Systems Medicine
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Gene summary

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Gene structures and expression levels

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Exon skipping events with PSIs in TCGA

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Exon skipping events with PSIs in GTEx

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Open reading frame (ORF) annotation in the exon skipping event

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Exon skipping events in the canonical protein sequence

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SNVs in the skipped exons with depth of coverage

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Splicing Quantitative Trait Loci (sQTLs) in the skipped exons

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon

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Related drugs with this gene

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Related diseases with this gene

Gene summary for ZNF521

check button Gene summary
Gene informationGene symbol

ZNF521

Gene ID

25925

Gene namezinc finger protein 521
SynonymsEHZF|Evi3
Cytomap

18q11.2

Type of geneprotein-coding
Descriptionzinc finger protein 521LYST-interacting protein 3early hematopoietic zinc finger protein
Modification date20180519
UniProtAcc

Q96K83

ContextPubMed: ZNF521 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract]
- Title (PMID)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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Exon skipping events across known transcript of Ensembl for ZNF521 from UCSC genome browser

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

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Gene isoform structures and expression levels for ZNF521

check button Expression levels of gene isoforms across TCGA.
gencode gene structure

check button Expression levels of gene isoforms across GTEx.
gencode gene structure


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Exon skipping events with PSIs in TCGA for ZNF521

check button Information of exkip skipping event in TCGA.
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_2985601822671913:22672045:22775123:22775208:22804308:2280475322775123:22775208ENSG00000198795.6ENST00000538137.2,ENST00000584787.1,ENST00000361524.3
exon_skip_2985621822775123:22775208:22803999:22804079:22804308:2280475322803999:22804079ENSG00000198795.6ENST00000399425.2
exon_skip_2985631822775123:22775208:22804308:22807661:22901971:2290215122804308:22807661ENSG00000198795.6ENST00000538137.2,ENST00000584787.1,ENST00000361524.3
exon_skip_2985641822807583:22807661:22901971:22902151:22930870:2293091122901971:22902151ENSG00000198795.6ENST00000577801.1,ENST00000399425.2,ENST00000580488.1,ENST00000538137.2,ENST00000361524.3
exon_skip_2985651822902100:22902151:22907369:22907412:22930870:2293091122907369:22907412ENSG00000198795.6ENST00000583005.1
exon_skip_2985661822902100:22902151:22925215:22925311:22930870:2293091122925215:22925311ENSG00000198795.6ENST00000579111.1
exon_skip_2985671822902100:22902151:22930870:22930911:22931968:2293203522930870:22930911ENSG00000198795.6ENST00000399425.2
exon_skip_2985691822902100:22902151:22930870:22930957:22931968:2293203522930870:22930957ENSG00000198795.6ENST00000538137.2

check button PSI values of skipped exons in TCGA.
psi tcga

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Exon skipping events with PSIs in GTEx for ZNF521

check button Information of exkip skipping event in GTEx
Exon skip IDchrExons involved in exon skippingSkipped exonENSGENSTs
exon_skip_2985601822671913:22672045:22775123:22775208:22804308:2280475322775123:22775208ENSG00000198795.6ENST00000361524.3,ENST00000584787.1,ENST00000538137.2
exon_skip_2985621822775123:22775208:22803999:22804079:22804308:2280475322803999:22804079ENSG00000198795.6ENST00000399425.2
exon_skip_2985631822775123:22775208:22804308:22807661:22901971:2290215122804308:22807661ENSG00000198795.6ENST00000361524.3,ENST00000584787.1,ENST00000538137.2
exon_skip_2985641822807583:22807661:22901971:22902151:22930870:2293091122901971:22902151ENSG00000198795.6ENST00000361524.3,ENST00000399425.2,ENST00000538137.2,ENST00000577801.1,ENST00000580488.1
exon_skip_2985651822902100:22902151:22907369:22907412:22930870:2293091122907369:22907412ENSG00000198795.6ENST00000583005.1
exon_skip_2985661822902100:22902151:22925215:22925311:22930870:2293091122925215:22925311ENSG00000198795.6ENST00000579111.1
exon_skip_2985671822902100:22902151:22930870:22930911:22931968:2293203522930870:22930911ENSG00000198795.6ENST00000399425.2
exon_skip_2985691822902100:22902151:22930870:22930957:22931968:2293203522930870:22930957ENSG00000198795.6ENST00000538137.2

check button PSI values of skipped exons in GTEx.
psi gtex

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for ZNF521

check button Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000053813722930870229309573UTR-3CDS
ENST000003615242277512322775208Frame-shift
ENST000005381372277512322775208Frame-shift
ENST000003615242280430822807661Frame-shift
ENST000005381372280430822807661Frame-shift
ENST000003615242290197122902151In-frame
ENST000005381372290197122902151In-frame

check button Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.
ENSTStart of skipped exonEnd of skipped exonORF
ENST0000053813722930870229309573UTR-3CDS
ENST000003615242277512322775208Frame-shift
ENST000005381372277512322775208Frame-shift
ENST000003615242280430822807661Frame-shift
ENST000005381372280430822807661Frame-shift
ENST000003615242290197122902151In-frame
ENST000005381372290197122902151In-frame

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Infer the effects of exon skipping event on protein functional features for ZNF521

check button Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.
prot feature distribution

check button Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003615244888131122901971229021511903691373
ENST000005381374270131122901971229021512394181373

check button Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.
ENSTLength of mRNALength of AA seq.Genomic startGenomic endmRNA startmRNA endAA startAA end
ENST000003615244888131122901971229021511903691373
ENST000005381374270131122901971229021512394181373

check button Lost protein functional features of individual exon skipping events in TCGA.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q96K83137311311ChainID=PRO_0000306871;Note=Zinc finger protein 521
Q96K83137311311ChainID=PRO_0000306871;Note=Zinc finger protein 521
Q96K8313737273SiteNote=Breakpoint for translocation to form PAX5-ZNF521
Q96K8313737273SiteNote=Breakpoint for translocation to form PAX5-ZNF521
Q96K8313734767Zinc fingerNote=C2H2-type 1%3B degenerate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042
Q96K8313734767Zinc fingerNote=C2H2-type 1%3B degenerate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042


check button Lost protein functional features of individual exon skipping events in GTEx.
UniProt acc.Start of exon skipping (AA)End of exon skipping (AA)Protein feature start (AA)Protein feature end (AA)Category of protein featureDescription of feature
Q96K83137311311ChainID=PRO_0000306871;Note=Zinc finger protein 521
Q96K83137311311ChainID=PRO_0000306871;Note=Zinc finger protein 521
Q96K8313737273SiteNote=Breakpoint for translocation to form PAX5-ZNF521
Q96K8313737273SiteNote=Breakpoint for translocation to form PAX5-ZNF521
Q96K8313734767Zinc fingerNote=C2H2-type 1%3B degenerate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042
Q96K8313734767Zinc fingerNote=C2H2-type 1%3B degenerate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042


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SNVs in the skipped exons for ZNF521

check button - Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.
lollipop

check button - Differential PSIs between mutated versus non-mutated samples.

check button - Non-synonymous mutations located in the skipped exons in TCGA.
Cancer typeSampleESIDSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
LIHCTCGA-DD-A39Y-01exon_skip_298563
22804309228076612280435922804359Frame_Shift_DelT-p.T1175fs
SARCTCGA-WK-A8Y0-01exon_skip_298563
22804309228076612280435922804359Frame_Shift_DelT-p.T1175fs
STADTCGA-HF-A5NB-01exon_skip_298563
22804309228076612280447822804478Frame_Shift_DelC-p.G1135fs
LIHCTCGA-DD-A3A0-01exon_skip_298563
22804309228076612280452422804524Frame_Shift_DelG-p.Q1120fs
LUADTCGA-05-4397-01exon_skip_298563
22804309228076612280491122804911Frame_Shift_DelG-p.R991fs
LIHCTCGA-DD-A39Y-01exon_skip_298563
22804309228076612280540422805404Frame_Shift_DelT-p.K826fs
LIHCTCGA-DD-A1EG-01exon_skip_298563
22804309228076612280568922805689Frame_Shift_DelA-p.F731fs
STADTCGA-BR-8382-01exon_skip_298563
22804309228076612280568922805689Frame_Shift_DelA-p.D732fs
LIHCTCGA-G3-A3CJ-01exon_skip_298563
22804309228076612280601122806011Frame_Shift_DelC-p.G625fs
LIHCTCGA-DD-A1EG-01exon_skip_298563
22804309228076612280606322806063Frame_Shift_DelG-p.L607fs
LIHCTCGA-DD-A39Y-01exon_skip_298563
22804309228076612280613622806136Frame_Shift_DelT-p.K582fs
LIHCTCGA-G3-A3CJ-01exon_skip_298563
22804309228076612280636822806368Frame_Shift_DelG-p.P505fs
STADTCGA-D7-A6EY-01exon_skip_298563
22804309228076612280691022806910Frame_Shift_DelT-p.E324fs
STADTCGA-D7-A6EY-01exon_skip_298563
22804309228076612280691022806910Frame_Shift_DelT-p.L325fs
LUADTCGA-MN-A4N4-01exon_skip_298563
22804309228076612280704222807054Frame_Shift_DelGGCCGCTCGGTCC-p.EDRAA276fs
LIHCTCGA-DD-A1EG-01exon_skip_298563
22804309228076612280751722807517Frame_Shift_DelA-p.F122fs
LIHCTCGA-DD-A3A0-01exon_skip_298563
22804309228076612280754122807541Frame_Shift_DelG-p.P114fs
LUADTCGA-MN-A4N4-01exon_skip_298563
22804309228076612280758522807585Frame_Shift_DelA-p.P99fs
LIHCTCGA-DD-A3A0-01exon_skip_298563
22804309228076612280758622807586Frame_Shift_DelG-p.P99fs
LIHCTCGA-G3-A3CJ-01exon_skip_298563
22804309228076612280758622807586Frame_Shift_DelG-p.P99fs
STADTCGA-HU-A4H4-01exon_skip_298564
22901972229021512290207722902077Frame_Shift_DelC-p.E39fs
LUADTCGA-49-4494-01exon_skip_298564
22901972229021512290213122902131Frame_Shift_DelC-p.D21fs
BLCATCGA-HQ-A5ND-01exon_skip_298563
22804309228076612280585922805860Frame_Shift_Ins-Ap.N675fs
LIHCTCGA-BC-A112-01exon_skip_298563
22804309228076612280660222806603Frame_Shift_Ins-Tp.Y427fs
COADTCGA-F4-6459-01exon_skip_298560
22775124227752082277520822775208Nonsense_MutationTAp.K1192X
HNSCTCGA-CV-7424-01exon_skip_298563
22804309228076612280452422804524Nonsense_MutationGAp.Q1120*
UCECTCGA-BS-A0UF-01exon_skip_298563
22804309228076612280466522804665Nonsense_MutationCAp.E1073*
LUADTCGA-75-6211-01exon_skip_298563
22804309228076612280489022804890Nonsense_MutationGAp.Q998*
BLCATCGA-BT-A2LB-01exon_skip_298563
22804309228076612280519022805190Nonsense_MutationCAp.E898*
LIHCTCGA-CC-A8HT-01exon_skip_298563
22804309228076612280535522805355Nonsense_MutationCAp.G843X
LGGTCGA-DU-6392-01exon_skip_298563
22804309228076612280539722805397Nonsense_MutationGAp.R829*
HNSCTCGA-BA-5152-01exon_skip_298563
22804309228076612280575422805754Nonsense_MutationGAp.Q710*
HNSCTCGA-CR-7394-01exon_skip_298563
22804309228076612280579322805793Nonsense_MutationCAp.E697*
LUADTCGA-50-8459-01exon_skip_298563
22804309228076612280602122806021Nonsense_MutationGAp.Q621*
COADTCGA-AA-3561-01exon_skip_298563
22804309228076612280639322806393Nonsense_MutationGAp.R497X
LUADTCGA-55-8506-01exon_skip_298563
22804309228076612280639322806393Nonsense_MutationGAp.R497*
LUADTCGA-78-7152-01exon_skip_298563
22804309228076612280658222806582Nonsense_MutationCAp.E434*
READTCGA-EI-6917-01exon_skip_298563
22804309228076612280658222806582Nonsense_MutationCAp.E434X
COADTCGA-CA-6717-01exon_skip_298563
22804309228076612280660622806606Nonsense_MutationTAp.K426X
LUADTCGA-50-7109-01exon_skip_298563
22804309228076612280690422806904Nonsense_MutationGTp.Y326*
LUADTCGA-05-4382-01exon_skip_298563
22804309228076612280700822807008Nonsense_MutationCAp.E292*
LUADTCGA-78-7150-01exon_skip_298563
22804309228076612280705022807050Nonsense_MutationGAp.R278*
LUADTCGA-97-8176-01exon_skip_298563
22804309228076612280707122807071Nonsense_MutationCAp.E271*
SKCMTCGA-EE-A2A1-06exon_skip_298563
22804309228076612280720922807209Nonsense_MutationCAp.E225*
LIHCTCGA-2Y-A9GZ-01exon_skip_298560
22775124227752082277512322775123Splice_SiteCA.

check button - Depth of coverage in the three exons composing exon skipping event
Depth of coverage in three exonsMutation description

check button - Non-synonymous mutations located in the skipped exons in CCLE.
SampleSkipped exon startSkipped exon endMutation startMutation endMutation typeReference seqMutation seqAAchange
GDM1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22775124227752082277515322775154Frame_Shift_DelAT-p.I1210fs
NCIH1838_LUNG22804309228076612280520522805205Frame_Shift_DelC-p.A894fs
NCIH1435_LUNG22804309228076612280611222806113Frame_Shift_Ins-Ap.L590fs
JHUEM2_ENDOMETRIUM22775124227752082277514422775144Missense_MutationTCp.H1213R
SKGT2_STOMACH22775124227752082277514922775149Missense_MutationCAp.Q1211H
SNGM_ENDOMETRIUM22804309228076612280445822804458Missense_MutationTCp.S1142G
IGROV1_OVARY22804309228076612280446322804463Missense_MutationCAp.C1140F
SNU46_UPPER_AERODIGESTIVE_TRACT22804309228076612280447922804479Missense_MutationCTp.G1135R
DOK_UPPER_AERODIGESTIVE_TRACT22804309228076612280451222804512Missense_MutationGTp.L1124M
MEWO_SKIN22804309228076612280455022804550Missense_MutationGAp.P1111L
NCIH64_LUNG22804309228076612280461722804617Missense_MutationGTp.P1089T
MEWO_SKIN22804309228076612280465822804658Missense_MutationCAp.R1075L
NAMALWA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280467622804676Missense_MutationGTp.S1069Y
DMS79_LUNG22804309228076612280468022804680Missense_MutationCTp.A1068T
LNCAPCLONEFGC_PROSTATE22804309228076612280471622804716Missense_MutationCAp.G1056W
OVCAR4_OVARY22804309228076612280474722804747Missense_MutationCGp.K1045N
FU97_STOMACH22804309228076612280475222804752Missense_MutationGTp.Q1044K
MCC13_SKIN22804309228076612280477022804770Missense_MutationGAp.H1038Y
HT115_LARGE_INTESTINE22804309228076612280482022804820Missense_MutationCTp.R1021H
HEC251_ENDOMETRIUM22804309228076612280487222804872Missense_MutationACp.L1004V
JHUEM7_ENDOMETRIUM22804309228076612280487422804874Missense_MutationACp.F1003C
JHU011_UPPER_AERODIGESTIVE_TRACT22804309228076612280488222804882Missense_MutationTAp.E1000D
TUHR10TKB_KIDNEY22804309228076612280488622804886Missense_MutationCTp.S999N
HS606T_FIBROBLAST22804309228076612280491122804911Missense_MutationGAp.R991W
JHUEM7_ENDOMETRIUM22804309228076612280494322804943Missense_MutationGAp.T980M
NCIH2052_PLEURA22804309228076612280507222805072Missense_MutationCTp.R937Q
KYSE30_OESOPHAGUS22804309228076612280508222805082Missense_MutationCAp.V934L
A431_SKIN22804309228076612280508722805087Missense_MutationCTp.C932Y
SNU81_LARGE_INTESTINE22804309228076612280510322805103Missense_MutationTGp.K927Q
JOPACA1_PANCREAS22804309228076612280512722805127Missense_MutationCTp.V919M
TE4_OESOPHAGUS22804309228076612280513522805135Missense_MutationCAp.S916I
HEC108_ENDOMETRIUM22804309228076612280519322805193Missense_MutationTCp.M897V
HS746T_STOMACH22804309228076612280522322805223Missense_MutationCAp.G887C
NCIH630_LARGE_INTESTINE22804309228076612280523322805233Missense_MutationCAp.E883D
CAL148_BREAST22804309228076612280523722805237Missense_MutationGAp.S882F
ZR751_BREAST22804309228076612280524222805242Missense_MutationGTp.D880E
YMB1E_BREAST22804309228076612280524222805242Missense_MutationGTp.D880E
NCIH1339_LUNG22804309228076612280526222805262Missense_MutationCTp.G874R
RH28_SOFT_TISSUE22804309228076612280528222805282Missense_MutationTGp.E867A
SNU1272_KIDNEY22804309228076612280537622805376Missense_MutationCTp.E836K
SKLU1_LUNG22804309228076612280537622805376Missense_MutationCTp.E836K
SLVL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280544622805446Missense_MutationCGp.K812N
HCT15_LARGE_INTESTINE22804309228076612280553122805531Missense_MutationTGp.K784T
HRT18_LARGE_INTESTINE22804309228076612280553122805531Missense_MutationTGp.K784T
NCIH889_LUNG22804309228076612280553422805534Missense_MutationTCp.H783R
A431_SKIN22804309228076612280561522805615Missense_MutationGAp.S756F
MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280564022805640Missense_MutationCGp.E748Q
SNU520_STOMACH22804309228076612280571422805714Missense_MutationCTp.R723H
HEC251_ENDOMETRIUM22804309228076612280572922805729Missense_MutationGAp.T718I
HCC2450_LUNG22804309228076612280574022805741Missense_MutationCAAGp.L714P
SW1271_LUNG22804309228076612280581422805814Missense_MutationTCp.T690A
CCK81_LARGE_INTESTINE22804309228076612280581422805814Missense_MutationTCp.T690A
HEC6_ENDOMETRIUM22804309228076612280588822805888Missense_MutationGAp.T665I
MOLP2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280590322805903Missense_MutationAGp.V660A
LNZTA3WT4_CENTRAL_NERVOUS_SYSTEM22804309228076612280593022805930Missense_MutationGTp.T651N
NCIH748_LUNG22804309228076612280596622805966Missense_MutationCAp.C639F
NCIH1435_LUNG22804309228076612280601422806014Missense_MutationAGp.V623A
NCIH650_LUNG22804309228076612280601722806017Missense_MutationGAp.A622V
ES7_BONE22804309228076612280601722806017Missense_MutationGAp.A622V
BEN_LUNG22804309228076612280607822806078Missense_MutationTAp.R602W
HS343T_FIBROBLAST22804309228076612280609622806096Missense_MutationGCp.H596D
GP5D_LARGE_INTESTINE22804309228076612280610222806102Missense_MutationAGp.Y594H
SW684_SOFT_TISSUE22804309228076612280617722806177Missense_MutationGAp.P569S
WM793_SKIN22804309228076612280618322806183Missense_MutationTCp.N567D
HCC1833_LUNG22804309228076612280624822806248Missense_MutationCGp.G545A
DANG_PANCREAS22804309228076612280626322806263Missense_MutationCGp.S540T
SNU81_LARGE_INTESTINE22804309228076612280634322806343Missense_MutationGTp.F513L
KYSE410_OESOPHAGUS22804309228076612280634722806347Missense_MutationGTp.A512E
COLO699_LUNG22804309228076612280643422806434Missense_MutationGAp.S483F
SNU1040_LARGE_INTESTINE22804309228076612280656122806561Missense_MutationAGp.Y441H
NCIH1417_LUNG22804309228076612280659822806598Missense_MutationCAp.M428I
BV173_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280660622806606Missense_MutationTGp.K426Q
CP67MEL_SKIN22804309228076612280669522806695Missense_MutationGAp.P396L
CI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280673222806732Missense_MutationTCp.K384E
SNU182_LIVER22804309228076612280681222806812Missense_MutationGAp.T357M
CORL303_LUNG22804309228076612280682222806822Missense_MutationCTp.V354M
NCIH1573_LUNG22804309228076612280691222806912Missense_MutationCGp.E324Q
HEC251_ENDOMETRIUM22804309228076612280695522806955Missense_MutationCAp.K309N
HCC2998_LARGE_INTESTINE22804309228076612280695522806955Missense_MutationCAp.K309N
RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280699122806991Missense_MutationCTp.M297I
COLO775_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280699122806991Missense_MutationCTp.M297I
HEC6_ENDOMETRIUM22804309228076612280701122807011Missense_MutationCTp.V291I
HT1080_SOFT_TISSUE22804309228076612280703222807032Missense_MutationCTp.V284I
HCC2450_LUNG22804309228076612280709122807091Missense_MutationTAp.H264L
MEWO_SKIN22804309228076612280710622807106Missense_MutationTCp.E259G
NCIH513_PLEURA22804309228076612280714122807141Missense_MutationCAp.K247N
SNUC5_LARGE_INTESTINE22804309228076612280717522807175Missense_MutationCGp.R236T
SNUC4_LARGE_INTESTINE22804309228076612280719722807197Missense_MutationCAp.D229Y
KYSE450_OESOPHAGUS22804309228076612280720422807204Missense_MutationCAp.R226S
SNU81_LARGE_INTESTINE22804309228076612280724922807249Missense_MutationACp.F211L
HEC251_ENDOMETRIUM22804309228076612280727422807274Missense_MutationTGp.K203T
EN_ENDOMETRIUM22804309228076612280729922807299Missense_MutationTCp.T195A
NCIH2171_LUNG22804309228076612280732322807323Missense_MutationCGp.D187H
BICR22_UPPER_AERODIGESTIVE_TRACT22804309228076612280733722807337Missense_MutationGAp.A182V
MUTZ5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22804309228076612280734122807341Missense_MutationCTp.A181T
SNU423_LIVER22804309228076612280741622807416Missense_MutationTGp.K156Q
RKN_SOFT_TISSUE22804309228076612280749622807496Missense_MutationCTp.R129H
JHUEM7_ENDOMETRIUM22804309228076612280751622807516Missense_MutationGTp.F122L
A2058_SKIN22804309228076612280764922807649Missense_MutationACp.V78G
DEL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE22901972229021512290203022902030Missense_MutationCAp.Q54H
HCC1195_LUNG22901972229021512290206522902065Missense_MutationCTp.D43N
HCC1359_LUNG22901972229021512290210022902100Missense_MutationCTp.C31Y
SNU81_LARGE_INTESTINE22930871229309572293090322930903Missense_MutationCTp.R3H
SNU81_LARGE_INTESTINE22930871229309112293090322930903Missense_MutationCTp.R3H
NCIH810_LUNG22804309228076612280431622804316Nonsense_MutationGTp.S1189*
NCIH1930_LUNG22804309228076612280468122804681Nonsense_MutationGTp.C1067*
BEN_LUNG22804309228076612280489022804890Nonsense_MutationGAp.Q998*
EVSAT_BREAST22804309228076612280539722805397Nonsense_MutationGAp.R829*
NCIH650_LUNG22804309228076612280602122806021Nonsense_MutationGAp.Q621*
NCIH2126_LUNG22804309228076612280640222806402Nonsense_MutationCAp.E494*
LNZTA3WT4_CENTRAL_NERVOUS_SYSTEM22804309228076612280645122806451Nonsense_MutationGTp.Y477*
NCIH1339_LUNG22804309228076612280652222806522Nonsense_MutationCAp.E454*
SW403_LARGE_INTESTINE22804309228076612280677922806779Nonsense_MutationGTp.S368*
NCIBL128_MATCHED_NORMAL_TISSUE22804309228076612280731422807314Nonsense_MutationTAp.K190*

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNF521

check button sQTL information located at the skipped exons.
Exon skip IDChromosomeThree exonsSkippped exonENSTCancer typeSNP idLocationDNA change (ref/var)P-value

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF521


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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF521


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RelatedDrugs for ZNF521

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF521

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource