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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for FUS |
 Gene summary |
| Gene information | Gene symbol | FUS | Gene ID | 2521 |
| Gene name | FUS RNA binding protein | |
| Synonyms | ALS6|ETM4|FUS1|HNRNPP2|POMP75|TLS | |
| Cytomap | 16p11.2 | |
| Type of gene | protein-coding | |
| Description | RNA-binding protein FUS75 kDa DNA-pairing proteinFUS/ERG chimeric proteinFUS/ERG fusion proteinfus-like proteinfused in sarcomafusion gene in myxoid liposarcomaheterogeneous nuclear ribonucleoprotein P2oncogene FUSoncogene TLStranslocated in lip | |
| Modification date | 20180527 | |
| UniProtAcc | P35637 | |
| Context | PubMed: FUS [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for FUS from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for FUS |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for FUS |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_135992 | 16 | 31193718:31193743:31193833:31193985:31195178:31195323 | 31193833:31193985 | ENSG00000089280.14 | ENST00000487509.2,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 |
| exon_skip_135993 | 16 | 31193718:31193743:31193833:31193985:31195181:31195323 | 31193833:31193985 | ENSG00000089280.14 | ENST00000380244.3 |
| exon_skip_136002 | 16 | 31195181:31195323:31195529:31195717:31196259:31196500 | 31195529:31195717 | ENSG00000089280.14 | ENST00000487509.2,ENST00000380244.3,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 |
| exon_skip_136011 | 16 | 31195529:31195717:31196259:31196500:31198122:31198157 | 31196259:31196500 | ENSG00000089280.14 | ENST00000380244.3,ENST00000568685.1,ENST00000254108.7 |
| exon_skip_136012 | 16 | 31195529:31195717:31196259:31196500:31199645:31199678 | 31196259:31196500 | ENSG00000089280.14 | ENST00000566605.1 |
| exon_skip_136020 | 16 | 31196484:31196500:31198122:31198157:31199645:31199678 | 31198122:31198157 | ENSG00000089280.14 | ENST00000380244.3,ENST00000568685.1,ENST00000254108.7 |
| exon_skip_136023 | 16 | 31196400:31196500:31199645:31199678:31200443:31200547 | 31199645:31199678 | ENSG00000089280.14 | ENST00000566605.1 |
| exon_skip_136025 | 16 | 31199645:31199678:31200440:31200547:31200985:31201016 | 31200440:31200547 | ENSG00000089280.14 | ENST00000568685.1 |
| exon_skip_136029 | 16 | 31199645:31199678:31200443:31200547:31200985:31201016 | 31200443:31200547 | ENSG00000089280.14 | ENST00000487509.2,ENST00000474990.1,ENST00000380244.3,ENST00000254108.7,ENST00000568901.2,ENST00000566605.1 |
| exon_skip_136034 | 16 | 31200443:31200547:31200985:31201115:31201360:31201441 | 31200985:31201115 | ENSG00000089280.14 | ENST00000487509.2,ENST00000474990.1,ENST00000380244.3,ENST00000568685.1,ENST00000254108.7,ENST00000568901.2,ENST00000566605.1 |
| exon_skip_136037 | 16 | 31200985:31201115:31201360:31201462:31201595:31201719 | 31201360:31201462 | ENSG00000089280.14 | ENST00000487509.2,ENST00000474990.1,ENST00000380244.3,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 |
| exon_skip_136038 | 16 | 31201360:31201462:31201595:31201719:31202062:31202163 | 31201595:31201719 | ENSG00000089280.14 | ENST00000487509.2,ENST00000474990.1,ENST00000380244.3,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 |
| exon_skip_136040 | 16 | 31201595:31201719:31202062:31202163:31202283:31202423 | 31202062:31202163 | ENSG00000089280.14 | ENST00000487509.2,ENST00000474990.1,ENST00000569760.1,ENST00000380244.3,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for FUS |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_135992 | 16 | 31193718:31193743:31193833:31193985:31195178:31195323 | 31193833:31193985 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000487509.2,ENST00000568685.1 |
| exon_skip_135993 | 16 | 31193718:31193743:31193833:31193985:31195181:31195323 | 31193833:31193985 | ENSG00000089280.14 | ENST00000380244.3 |
| exon_skip_136002 | 16 | 31195181:31195323:31195529:31195717:31196259:31196500 | 31195529:31195717 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000380244.3,ENST00000487509.2,ENST00000568685.1 |
| exon_skip_136011 | 16 | 31195529:31195717:31196259:31196500:31198122:31198157 | 31196259:31196500 | ENSG00000089280.14 | ENST00000254108.7,ENST00000380244.3,ENST00000568685.1 |
| exon_skip_136012 | 16 | 31195529:31195717:31196259:31196500:31199645:31199678 | 31196259:31196500 | ENSG00000089280.14 | ENST00000566605.1 |
| exon_skip_136020 | 16 | 31196484:31196500:31198122:31198157:31199645:31199678 | 31198122:31198157 | ENSG00000089280.14 | ENST00000254108.7,ENST00000380244.3,ENST00000568685.1 |
| exon_skip_136023 | 16 | 31196400:31196500:31199645:31199678:31200443:31200547 | 31199645:31199678 | ENSG00000089280.14 | ENST00000566605.1 |
| exon_skip_136025 | 16 | 31199645:31199678:31200440:31200547:31200985:31201016 | 31200440:31200547 | ENSG00000089280.14 | ENST00000568685.1 |
| exon_skip_136029 | 16 | 31199645:31199678:31200443:31200547:31200985:31201016 | 31200443:31200547 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000380244.3,ENST00000487509.2,ENST00000474990.1,ENST00000568901.2 |
| exon_skip_136034 | 16 | 31200443:31200547:31200985:31201115:31201360:31201441 | 31200985:31201115 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000380244.3,ENST00000487509.2,ENST00000568685.1,ENST00000474990.1,ENST00000568901.2 |
| exon_skip_136037 | 16 | 31200985:31201115:31201360:31201462:31201595:31201719 | 31201360:31201462 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000380244.3,ENST00000487509.2,ENST00000568685.1,ENST00000474990.1 |
| exon_skip_136038 | 16 | 31201360:31201462:31201595:31201719:31202062:31202163 | 31201595:31201719 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000380244.3,ENST00000487509.2,ENST00000568685.1,ENST00000474990.1 |
| exon_skip_136040 | 16 | 31201595:31201719:31202062:31202163:31202283:31202423 | 31202062:31202163 | ENSG00000089280.14 | ENST00000254108.7,ENST00000566605.1,ENST00000380244.3,ENST00000487509.2,ENST00000568685.1,ENST00000474990.1,ENST00000569760.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for FUS |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000254108 | 31193833 | 31193985 | Frame-shift |
| ENST00000254108 | 31195529 | 31195717 | Frame-shift |
| ENST00000254108 | 31196259 | 31196500 | Frame-shift |
| ENST00000254108 | 31198122 | 31198157 | Frame-shift |
| ENST00000254108 | 31200443 | 31200547 | Frame-shift |
| ENST00000254108 | 31200985 | 31201115 | Frame-shift |
| ENST00000254108 | 31201595 | 31201719 | Frame-shift |
| ENST00000254108 | 31202062 | 31202163 | Frame-shift |
| ENST00000254108 | 31201360 | 31201462 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000254108 | 31193833 | 31193985 | Frame-shift |
| ENST00000254108 | 31195529 | 31195717 | Frame-shift |
| ENST00000254108 | 31196259 | 31196500 | Frame-shift |
| ENST00000254108 | 31198122 | 31198157 | Frame-shift |
| ENST00000254108 | 31200443 | 31200547 | Frame-shift |
| ENST00000254108 | 31200985 | 31201115 | Frame-shift |
| ENST00000254108 | 31201595 | 31201719 | Frame-shift |
| ENST00000254108 | 31202062 | 31202163 | Frame-shift |
| ENST00000254108 | 31201360 | 31201462 | In-frame |
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Infer the effects of exon skipping event on protein functional features for FUS |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000254108 | 2071 | 526 | 31201360 | 31201462 | 1172 | 1273 | 355 | 389 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000254108 | 2071 | 526 | 31201360 | 31201462 | 1172 | 1273 | 355 | 389 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| P35637 | 355 | 389 | 358 | 363 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2LA6 |
| P35637 | 355 | 389 | 365 | 368 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2LA6 |
| P35637 | 355 | 389 | 379 | 381 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2LCW |
| P35637 | 355 | 389 | 1 | 526 | Chain | ID=PRO_0000081591;Note=RNA-binding protein FUS |
| P35637 | 355 | 389 | 371 | 526 | Compositional bias | Note=Arg/Gly-rich |
| P35637 | 355 | 389 | 285 | 371 | Domain | Note=RRM;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00176 |
| P35637 | 355 | 389 | 377 | 377 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| P35637 | 355 | 389 | 383 | 383 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| P35637 | 355 | 389 | 386 | 386 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| P35637 | 355 | 389 | 388 | 388 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| P35637 | 355 | 389 | 358 | 363 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2LA6 |
| P35637 | 355 | 389 | 365 | 368 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2LA6 |
| P35637 | 355 | 389 | 379 | 381 | Beta strand | Ontology_term=ECO:0000244;evidence=ECO:0000244|PDB:2LCW |
| P35637 | 355 | 389 | 1 | 526 | Chain | ID=PRO_0000081591;Note=RNA-binding protein FUS |
| P35637 | 355 | 389 | 371 | 526 | Compositional bias | Note=Arg/Gly-rich |
| P35637 | 355 | 389 | 285 | 371 | Domain | Note=RRM;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00176 |
| P35637 | 355 | 389 | 377 | 377 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| P35637 | 355 | 389 | 383 | 383 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| P35637 | 355 | 389 | 386 | 386 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
| P35637 | 355 | 389 | 388 | 388 | Modified residue | Note=Asymmetric dimethylarginine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12964758;Dbxref=PMID:12964758 |
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SNVs in the skipped exons for FUS |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_135992 exon_skip_135993 | 31193834 | 31193985 | 31193846 | 31193846 | Frame_Shift_Del | C | - | p.Y17fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_135992 exon_skip_135993 | 31193834 | 31193985 | 31193856 | 31193856 | Frame_Shift_Del | C | - | p.P21fs |
| HNSC | TCGA-CN-4723-01 | exon_skip_135992 exon_skip_135993 | 31193834 | 31193985 | 31193962 | 31193962 | Frame_Shift_Del | C | - | p.S56fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_136002 | 31195530 | 31195717 | 31195576 | 31195576 | Frame_Shift_Del | G | - | p.G128fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_136002 | 31195530 | 31195717 | 31195576 | 31195576 | Frame_Shift_Del | G | - | p.G128fs |
| COAD | TCGA-G4-6628-01 | exon_skip_136002 | 31195530 | 31195717 | 31195645 | 31195645 | Frame_Shift_Del | C | - | p.N149fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_136002 | 31195530 | 31195717 | 31195645 | 31195645 | Frame_Shift_Del | C | - | p.P152fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_136025 exon_skip_136029 | 31200441 | 31200547 | 31200487 | 31200487 | Frame_Shift_Del | G | - | p.L292fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_136025 exon_skip_136029 | 31200444 | 31200547 | 31200487 | 31200487 | Frame_Shift_Del | G | - | p.L292fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_136037 | 31201361 | 31201462 | 31201396 | 31201396 | Frame_Shift_Del | T | - | p.F368fs |
| KIRC | TCGA-B8-5553-01 | exon_skip_136040 | 31202063 | 31202163 | 31202116 | 31202116 | Frame_Shift_Del | C | - | p.A449fs |
| COAD | TCGA-CK-4948-01 | exon_skip_135992 exon_skip_135993 | 31193834 | 31193985 | 31193862 | 31193862 | Nonsense_Mutation | C | T | p.Q23X |
| BLCA | TCGA-DK-A6B6-01 | exon_skip_136002 | 31195530 | 31195717 | 31195546 | 31195546 | Nonsense_Mutation | C | T | p.Q118* |
| BLCA | TCGA-BT-A0YX-01 | exon_skip_136002 | 31195530 | 31195717 | 31195651 | 31195651 | Nonsense_Mutation | C | T | p.Q153* |
| BLCA | TCGA-E7-A7XN-01 | exon_skip_136002 | 31195530 | 31195717 | 31195651 | 31195651 | Nonsense_Mutation | C | T | p.Q153* |
| HNSC | TCGA-CQ-A4CA-01 | exon_skip_136002 | 31195530 | 31195717 | 31195651 | 31195651 | Nonsense_Mutation | C | T | p.Q153* |
| ESCA | TCGA-R6-A6DN-01 | exon_skip_136023 | 31199646 | 31199678 | 31199660 | 31199660 | Nonsense_Mutation | G | T | p.G272* |
| BLCA | TCGA-DK-A3IU-01 | exon_skip_136037 | 31201361 | 31201462 | 31201394 | 31201394 | Nonsense_Mutation | C | A | p.S367* |
| KIRC | TCGA-B8-5553-01 | exon_skip_136040 | 31202063 | 31202163 | 31202112 | 31202112 | Nonsense_Mutation | A | T | p.K448X |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| HEC108_ENDOMETRIUM | 31202063 | 31202163 | 31202115 | 31202116 | Frame_Shift_Ins | - | C | p.A449fs |
| HEC108_ENDOMETRIUM | 31193834 | 31193985 | 31193836 | 31193836 | Missense_Mutation | A | G | p.Y14C |
| REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 31195530 | 31195717 | 31195568 | 31195568 | Missense_Mutation | C | A | p.P125H |
| UACC893_BREAST | 31195530 | 31195717 | 31195688 | 31195688 | Missense_Mutation | G | C | p.S165T |
| CCK81_LARGE_INTESTINE | 31196260 | 31196500 | 31196313 | 31196313 | Missense_Mutation | G | A | p.G193S |
| HPAC_PANCREAS | 31196260 | 31196500 | 31196412 | 31196412 | Missense_Mutation | G | A | p.G226S |
| HCC1599_BREAST | 31200441 | 31200547 | 31200545 | 31200545 | Missense_Mutation | A | C | p.K312Q |
| HCC1599_BREAST | 31200444 | 31200547 | 31200545 | 31200545 | Missense_Mutation | A | C | p.K312Q |
| SKPNDW_BONE | 31200986 | 31201115 | 31201028 | 31201028 | Missense_Mutation | G | C | p.D327H |
| PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 31200986 | 31201115 | 31201088 | 31201088 | Missense_Mutation | G | A | p.A347T |
| CL11_LARGE_INTESTINE | 31201361 | 31201462 | 31201373 | 31201373 | Missense_Mutation | C | T | p.S360F |
| SARC9371_BONE | 31201361 | 31201462 | 31201408 | 31201408 | Missense_Mutation | C | T | p.R372W |
| A549_LUNG | 31201361 | 31201462 | 31201442 | 31201442 | Missense_Mutation | G | A | p.R383H |
| JHUEM1_ENDOMETRIUM | 31201361 | 31201462 | 31201442 | 31201442 | Missense_Mutation | G | A | p.R383H |
| LU99_LUNG | 31201361 | 31201462 | 31201442 | 31201442 | Missense_Mutation | G | A | p.R383H |
| SKMEL1_SKIN | 31201361 | 31201462 | 31201442 | 31201442 | Missense_Mutation | G | A | p.R383H |
| JHU028_LUNG | 31201361 | 31201462 | 31201442 | 31201442 | Missense_Mutation | G | A | p.R383H |
| HEC59_ENDOMETRIUM | 31201596 | 31201719 | 31201659 | 31201659 | Missense_Mutation | C | T | p.P411L |
| KYSE220_OESOPHAGUS | 31201596 | 31201719 | 31201712 | 31201712 | Missense_Mutation | C | T | p.P429S |
| L1236_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 31202063 | 31202163 | 31202158 | 31202158 | Missense_Mutation | A | T | p.H463L |
| CCK81_LARGE_INTESTINE | 31198123 | 31198157 | 31198124 | 31198124 | Splice_Site | G | A | p.G256R |
| RH28_SOFT_TISSUE | 31201596 | 31201719 | 31201597 | 31201597 | Splice_Site | A | G | p.G390G |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for FUS |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_135992 | 16 | 31193718:31193743:31193833:31193985:31195178:31195323 | 31193833:31193985 | ENST00000487509.2,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 | LGG | rs741810 | chr16:31193942 | C/A | 5.89e-04 |
| exon_skip_135992 | 16 | 31193718:31193743:31193833:31193985:31195178:31195323 | 31193833:31193985 | ENST00000487509.2,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 | OV | rs741810 | chr16:31193942 | C/A | 1.28e-03 |
| exon_skip_135992 | 16 | 31193718:31193743:31193833:31193985:31195178:31195323 | 31193833:31193985 | ENST00000487509.2,ENST00000568685.1,ENST00000254108.7,ENST00000566605.1 | PRAD | rs741810 | chr16:31193942 | C/A | 1.62e-03 |
| exon_skip_135993 | 16 | 31193718:31193743:31193833:31193985:31195181:31195323 | 31193833:31193985 | ENST00000380244.3 | LGG | rs741810 | chr16:31193942 | C/A | 5.89e-04 |
| exon_skip_135993 | 16 | 31193718:31193743:31193833:31193985:31195181:31195323 | 31193833:31193985 | ENST00000380244.3 | OV | rs741810 | chr16:31193942 | C/A | 1.28e-03 |
| exon_skip_135993 | 16 | 31193718:31193743:31193833:31193985:31195181:31195323 | 31193833:31193985 | ENST00000380244.3 | PRAD | rs741810 | chr16:31193942 | C/A | 1.62e-03 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for FUS |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for FUS |
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RelatedDrugs for FUS |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FUS |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| FUS | C1842675 | AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder) | 6 | UNIPROT |
| FUS | C0206634 | Liposarcoma, Myxoid | 2 | CTD_human;ORPHANET |
| FUS | C3539195 | TREMOR, HEREDITARY ESSENTIAL, 4 | 1 | UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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