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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for UBR4 |
 Gene summary |
| Gene information | Gene symbol | UBR4 | Gene ID | 23352 |
| Gene name | ubiquitin protein ligase E3 component n-recognin 4 | |
| Synonyms | RBAF600|ZUBR1|p600 | |
| Cytomap | 1p36.13 | |
| Type of gene | protein-coding | |
| Description | E3 ubiquitin-protein ligase UBR4N-recognin-4RING-type E3 ubiquitin transferase UBR4retinoblastoma-associated factor 600-like proteinretinoblastoma-associated factor of 600 kDazinc finger UBR1-type protein 1 | |
| Modification date | 20180523 | |
| UniProtAcc | Q5T4S7 | |
| Context | PubMed: UBR4 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| UBR4 | GO:0006511 | ubiquitin-dependent protein catabolic process | 23932781 |
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Exon skipping events across known transcript of Ensembl for UBR4 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for UBR4 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for UBR4 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_22234 | 1 | 19403233:19403396:19404278:19404341:19404469:19404552 | 19404278:19404341 | ENSG00000127481.10 | ENST00000375267.2 |
| exon_skip_22241 | 1 | 19403233:19403396:19404469:19404560:19407842:19408067 | 19404469:19404560 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375225.3,ENST00000375254.3,ENST00000429347.2,ENST00000543981.1,ENST00000375217.2 |
| exon_skip_22260 | 1 | 19404469:19404560:19407842:19408067:19410997:19411192 | 19407842:19408067 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375254.3,ENST00000429347.2,ENST00000375267.2,ENST00000543981.1,ENST00000375217.2 |
| exon_skip_22264 | 1 | 19413172:19413315:19414309:19414423:19415252:19415471 | 19414309:19414423 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375254.3,ENST00000429347.2,ENST00000375267.2,ENST00000543981.1,ENST00000375217.2 |
| exon_skip_22265 | 1 | 19415252:19415471:19419312:19419412:19419806:19419934 | 19419312:19419412 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375254.3,ENST00000429347.2,ENST00000375267.2,ENST00000543981.1,ENST00000375217.2 |
| exon_skip_22266 | 1 | 19420588:19420633:19421399:19421519:19422038:19422146 | 19421399:19421519 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375254.3,ENST00000375267.2,ENST00000543981.1,ENST00000375217.2,ENST00000483922.1,ENST00000467272.2 |
| exon_skip_22269 | 1 | 19423016:19423144:19423686:19423774:19426090:19426149 | 19423686:19423774 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375254.3,ENST00000429347.2,ENST00000375267.2,ENST00000375217.2,ENST00000467272.2 |
| exon_skip_22271 | 1 | 19423686:19423774:19426090:19426171:19426869:19427067 | 19426090:19426171 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375224.1,ENST00000375254.3,ENST00000375267.2,ENST00000375217.2 |
| exon_skip_22275 | 1 | 19433330:19433460:19436589:19436717:19436873:19436958 | 19436589:19436717 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000494503.1 |
| exon_skip_22276 | 1 | 19436873:19436958:19437235:19437326:19439017:19439181 | 19437235:19437326 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375254.3,ENST00000375267.2,ENST00000375217.2 |
| exon_skip_22278 | 1 | 19444316:19444404:19445365:19445451:19446050:19446195 | 19445365:19445451 | ENSG00000127481.10 | ENST00000375226.2,ENST00000375254.3,ENST00000375267.2,ENST00000375217.2 |
| exon_skip_22279 | 1 | 19451034:19451184:19452096:19452193:19452939:19453149 | 19452096:19452193 | ENSG00000127481.10 | ENST00000475973.1 |
| exon_skip_22280 | 1 | 19451034:19451184:19452939:19453149:19454116:19454195 | 19452939:19453149 | ENSG00000127481.10 | ENST00000425413.1,ENST00000375226.2,ENST00000417040.1,ENST00000375254.3,ENST00000375267.2,ENST00000375217.2 |
| exon_skip_22284 | 1 | 19465576:19465714:19467281:19467386:19467840:19468018 | 19467281:19467386 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2 |
| exon_skip_22287 | 1 | 19465576:19465714:19467840:19468018:19468140:19468268 | 19467840:19468018 | ENSG00000127481.10 | ENST00000425413.1,ENST00000375226.2,ENST00000417040.1,ENST00000375217.2 |
| exon_skip_22293 | 1 | 19467281:19467386:19467840:19468018:19468140:19468271 | 19467840:19468018 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2 |
| exon_skip_22296 | 1 | 19472286:19472427:19472516:19472600:19473319:19473494 | 19472516:19472600 | ENSG00000127481.10 | ENST00000425413.1,ENST00000375217.2 |
| exon_skip_22298 | 1 | 19475056:19475120:19476256:19476289:19477070:19477287 | 19476256:19476289 | ENSG00000127481.10 | ENST00000375226.2,ENST00000417040.1 |
| exon_skip_22300 | 1 | 19475056:19475120:19477070:19477287:19478136:19478194 | 19477070:19477287 | ENSG00000127481.10 | ENST00000425413.1,ENST00000375254.3,ENST00000375267.2,ENST00000375217.2 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for UBR4 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_22234 | 1 | 19403233:19403396:19404278:19404341:19404469:19404552 | 19404278:19404341 | ENSG00000127481.10 | ENST00000375267.2 |
| exon_skip_22241 | 1 | 19403233:19403396:19404469:19404560:19407842:19408067 | 19404469:19404560 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375217.2,ENST00000375226.2,ENST00000375225.3,ENST00000375224.1,ENST00000429347.2,ENST00000543981.1 |
| exon_skip_22260 | 1 | 19404469:19404560:19407842:19408067:19410997:19411192 | 19407842:19408067 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000375224.1,ENST00000429347.2,ENST00000543981.1 |
| exon_skip_22264 | 1 | 19413172:19413315:19414309:19414423:19415252:19415471 | 19414309:19414423 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000375224.1,ENST00000429347.2,ENST00000543981.1 |
| exon_skip_22265 | 1 | 19415252:19415471:19419312:19419412:19419806:19419934 | 19419312:19419412 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000375224.1,ENST00000429347.2,ENST00000543981.1 |
| exon_skip_22266 | 1 | 19420588:19420633:19421399:19421519:19422038:19422146 | 19421399:19421519 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000375224.1,ENST00000543981.1,ENST00000467272.2,ENST00000483922.1 |
| exon_skip_22269 | 1 | 19423016:19423144:19423686:19423774:19426090:19426149 | 19423686:19423774 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000375224.1,ENST00000429347.2,ENST00000467272.2 |
| exon_skip_22271 | 1 | 19423686:19423774:19426090:19426171:19426869:19427067 | 19426090:19426171 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000375224.1 |
| exon_skip_22275 | 1 | 19433330:19433460:19436589:19436717:19436873:19436958 | 19436589:19436717 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000494503.1 |
| exon_skip_22276 | 1 | 19436873:19436958:19437235:19437326:19439017:19439181 | 19437235:19437326 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2 |
| exon_skip_22278 | 1 | 19444316:19444404:19445365:19445451:19446050:19446195 | 19445365:19445451 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2 |
| exon_skip_22279 | 1 | 19451034:19451184:19452096:19452193:19452939:19453149 | 19452096:19452193 | ENSG00000127481.10 | ENST00000475973.1 |
| exon_skip_22280 | 1 | 19451034:19451184:19452939:19453149:19454116:19454195 | 19452939:19453149 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000375226.2,ENST00000425413.1,ENST00000417040.1 |
| exon_skip_22284 | 1 | 19465576:19465714:19467281:19467386:19467840:19468018 | 19467281:19467386 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2 |
| exon_skip_22287 | 1 | 19465576:19465714:19467840:19468018:19468140:19468268 | 19467840:19468018 | ENSG00000127481.10 | ENST00000375217.2,ENST00000375226.2,ENST00000425413.1,ENST00000417040.1 |
| exon_skip_22293 | 1 | 19467281:19467386:19467840:19468018:19468140:19468271 | 19467840:19468018 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2 |
| exon_skip_22296 | 1 | 19472286:19472427:19472516:19472600:19473319:19473494 | 19472516:19472600 | ENSG00000127481.10 | ENST00000375217.2,ENST00000425413.1 |
| exon_skip_22298 | 1 | 19475056:19475120:19476256:19476289:19477070:19477287 | 19476256:19476289 | ENSG00000127481.10 | ENST00000375226.2,ENST00000417040.1 |
| exon_skip_22300 | 1 | 19475056:19475120:19477070:19477287:19478136:19478194 | 19477070:19477287 | ENSG00000127481.10 | ENST00000375254.3,ENST00000375267.2,ENST00000375217.2,ENST00000425413.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for UBR4 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000375254 | 19404469 | 19404560 | Frame-shift |
| ENST00000375254 | 19419312 | 19419412 | Frame-shift |
| ENST00000375254 | 19423686 | 19423774 | Frame-shift |
| ENST00000375254 | 19436589 | 19436717 | Frame-shift |
| ENST00000375254 | 19437235 | 19437326 | Frame-shift |
| ENST00000375254 | 19445365 | 19445451 | Frame-shift |
| ENST00000375254 | 19467840 | 19468018 | Frame-shift |
| ENST00000375254 | 19477070 | 19477287 | Frame-shift |
| ENST00000375254 | 19407842 | 19408067 | In-frame |
| ENST00000375254 | 19414309 | 19414423 | In-frame |
| ENST00000375254 | 19421399 | 19421519 | In-frame |
| ENST00000375254 | 19426090 | 19426171 | In-frame |
| ENST00000375254 | 19452939 | 19453149 | In-frame |
| ENST00000375254 | 19467281 | 19467386 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000375254 | 19404469 | 19404560 | Frame-shift |
| ENST00000375254 | 19419312 | 19419412 | Frame-shift |
| ENST00000375254 | 19423686 | 19423774 | Frame-shift |
| ENST00000375254 | 19436589 | 19436717 | Frame-shift |
| ENST00000375254 | 19437235 | 19437326 | Frame-shift |
| ENST00000375254 | 19445365 | 19445451 | Frame-shift |
| ENST00000375254 | 19467840 | 19468018 | Frame-shift |
| ENST00000375254 | 19477070 | 19477287 | Frame-shift |
| ENST00000375254 | 19407842 | 19408067 | In-frame |
| ENST00000375254 | 19414309 | 19414423 | In-frame |
| ENST00000375254 | 19421399 | 19421519 | In-frame |
| ENST00000375254 | 19426090 | 19426171 | In-frame |
| ENST00000375254 | 19452939 | 19453149 | In-frame |
| ENST00000375254 | 19467281 | 19467386 | In-frame |
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Infer the effects of exon skipping event on protein functional features for UBR4 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000375254 | 15923 | 5183 | 19467281 | 19467386 | 8517 | 8621 | 2829 | 2864 |
| ENST00000375254 | 15923 | 5183 | 19452939 | 19453149 | 9257 | 9466 | 3076 | 3146 |
| ENST00000375254 | 15923 | 5183 | 19426090 | 19426171 | 13250 | 13330 | 4407 | 4434 |
| ENST00000375254 | 15923 | 5183 | 19421399 | 19421519 | 13655 | 13774 | 4542 | 4582 |
| ENST00000375254 | 15923 | 5183 | 19414309 | 19414423 | 14459 | 14572 | 4810 | 4848 |
| ENST00000375254 | 15923 | 5183 | 19407842 | 19408067 | 15037 | 15261 | 5003 | 5077 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000375254 | 15923 | 5183 | 19467281 | 19467386 | 8517 | 8621 | 2829 | 2864 |
| ENST00000375254 | 15923 | 5183 | 19452939 | 19453149 | 9257 | 9466 | 3076 | 3146 |
| ENST00000375254 | 15923 | 5183 | 19426090 | 19426171 | 13250 | 13330 | 4407 | 4434 |
| ENST00000375254 | 15923 | 5183 | 19421399 | 19421519 | 13655 | 13774 | 4542 | 4582 |
| ENST00000375254 | 15923 | 5183 | 19414309 | 19414423 | 14459 | 14572 | 4810 | 4848 |
| ENST00000375254 | 15923 | 5183 | 19407842 | 19408067 | 15037 | 15261 | 5003 | 5077 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for UBR4 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_22260 | 19407843 | 19408067 | 19407933 | 19407933 | Frame_Shift_Del | G | - | p.P5048fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_22271 | 19426091 | 19426171 | 19426120 | 19426120 | Frame_Shift_Del | A | - | p.Y4425fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_22275 | 19436590 | 19436717 | 19436608 | 19436608 | Frame_Shift_Del | G | - | p.P4029fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_22276 | 19437236 | 19437326 | 19437277 | 19437277 | Frame_Shift_Del | C | - | p.V3951fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_22276 | 19437236 | 19437326 | 19437307 | 19437307 | Frame_Shift_Del | G | - | p.Q3942fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| PRAD | TCGA-CH-5769-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| STAD | TCGA-BR-4257-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.M2803fs |
| STAD | TCGA-CG-4442-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.M2803fs |
| STAD | TCGA-CG-4442-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| STAD | TCGA-CG-5728-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.M2803fs |
| STAD | TCGA-CG-5733-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.M2803fs |
| UCEC | TCGA-AP-A0LE-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| UCEC | TCGA-D1-A0ZS-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| UCEC | TCGA-D1-A17B-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| UCEC | TCGA-D1-A17D-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| UCEC | TCGA-D1-A17M-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_22300 | 19477071 | 19477287 | 19477100 | 19477100 | Frame_Shift_Del | G | - | p.P2467fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_22300 | 19477071 | 19477287 | 19477100 | 19477100 | Frame_Shift_Del | G | - | p.P2467fs |
| HNSC | TCGA-CR-5248-01 | exon_skip_22280 | 19452940 | 19453149 | 19453067 | 19453067 | Nonsense_Mutation | G | C | p.S3104* |
| LUAD | TCGA-MN-A4N5-01 | exon_skip_22287 exon_skip_22293 | 19467841 | 19468018 | 19468000 | 19468000 | Nonsense_Mutation | C | A | p.E2777* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SNGM_ENDOMETRIUM | 19421400 | 19421519 | 19421482 | 19421482 | Frame_Shift_Del | C | - | p.G4555fs |
| HEC265_ENDOMETRIUM | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| EFO27_OVARY | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| HCT116_LARGE_INTESTINE | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| SNUC5_LARGE_INTESTINE | 19467841 | 19468018 | 19467923 | 19467923 | Frame_Shift_Del | G | - | p.P2802fs |
| OC316_OVARY | 19477071 | 19477287 | 19477191 | 19477191 | Frame_Shift_Del | G | - | p.P2437fs |
| OC314_OVARY | 19477071 | 19477287 | 19477191 | 19477191 | Frame_Shift_Del | G | - | p.P2437fs |
| TE14_OESOPHAGUS | 19407843 | 19408067 | 19407951 | 19407951 | Missense_Mutation | G | A | p.A5042V |
| C33A_CERVIX | 19407843 | 19408067 | 19407976 | 19407976 | Missense_Mutation | C | T | p.G5034R |
| UMUC14_URINARY_TRACT | 19407843 | 19408067 | 19407979 | 19407979 | Missense_Mutation | C | T | p.D5033N |
| SISO_CERVIX | 19407843 | 19408067 | 19408062 | 19408062 | Missense_Mutation | C | T | p.R5005Q |
| GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19407843 | 19408067 | 19408062 | 19408062 | Missense_Mutation | C | T | p.R5005Q |
| MPP89_PLEURA | 19407843 | 19408067 | 19408062 | 19408062 | Missense_Mutation | C | T | p.R5005Q |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 19419313 | 19419412 | 19419320 | 19419320 | Missense_Mutation | C | G | p.G4735A |
| SKNDZ_AUTONOMIC_GANGLIA | 19419313 | 19419412 | 19419341 | 19419341 | Missense_Mutation | C | T | p.G4728D |
| NOS1_BONE | 19419313 | 19419412 | 19419345 | 19419345 | Missense_Mutation | G | A | p.R4727W |
| SNGM_ENDOMETRIUM | 19421400 | 19421519 | 19421411 | 19421411 | Missense_Mutation | T | C | p.S4579G |
| SNU175_LARGE_INTESTINE | 19423687 | 19423774 | 19423744 | 19423744 | Missense_Mutation | G | A | p.R4445W |
| M14_SKIN | 19426091 | 19426171 | 19426135 | 19426135 | Missense_Mutation | G | A | p.P4420S |
| MDAMB435S_SKIN | 19426091 | 19426171 | 19426135 | 19426135 | Missense_Mutation | G | A | p.P4420S |
| SKM1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19436590 | 19436717 | 19436627 | 19436627 | Missense_Mutation | A | C | p.L4023R |
| DND41_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19437236 | 19437326 | 19437310 | 19437310 | Missense_Mutation | T | C | p.T3940A |
| TE11_OESOPHAGUS | 19445366 | 19445451 | 19445385 | 19445385 | Missense_Mutation | G | A | p.P3508S |
| NCIH513_PLEURA | 19445366 | 19445451 | 19445422 | 19445422 | Missense_Mutation | C | G | p.E3495D |
| SNU308_BILIARY_TRACT | 19467282 | 19467386 | 19467294 | 19467294 | Missense_Mutation | T | C | p.T2861A |
| HT115_LARGE_INTESTINE | 19467282 | 19467386 | 19467314 | 19467314 | Missense_Mutation | T | C | p.D2854G |
| CTV1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19467841 | 19468018 | 19467943 | 19467943 | Missense_Mutation | C | T | p.G2796S |
| DU145_PROSTATE | 19477071 | 19477287 | 19477147 | 19477147 | Missense_Mutation | T | C | p.N2452D |
| UOK101_KIDNEY | 19477071 | 19477287 | 19477147 | 19477147 | Missense_Mutation | T | C | p.N2452D |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 19477071 | 19477287 | 19477184 | 19477184 | Missense_Mutation | T | G | p.E2439D |
| DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 19477071 | 19477287 | 19477184 | 19477184 | Missense_Mutation | T | G | p.E2439D |
| MALME3M_SKIN | 19414310 | 19414423 | 19414408 | 19414408 | Nonsense_Mutation | G | A | p.Q4816* |
| PWR1E_PROSTATE | 19445366 | 19445451 | 19445445 | 19445445 | Nonsense_Mutation | C | A | p.E3488* |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for UBR4 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for UBR4 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for UBR4 |
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RelatedDrugs for UBR4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBR4 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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