|
||||||
|
 | |
| |
| |
| |
| Open reading frame (ORF) annotation in the exon skipping event |
| |
| |
| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
| |
|
Gene summary for ZNF609 |
 Gene summary |
| Gene information | Gene symbol | ZNF609 | Gene ID | 23060 |
| Gene name | zinc finger protein 609 | |
| Synonyms | - | |
| Cytomap | 15q22.31 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 609 | |
| Modification date | 20180519 | |
| UniProtAcc | O15014 | |
| Context | PubMed: ZNF609 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| ZNF609 | GO:2000291 | regulation of myoblast proliferation | 28344082 |
Top |
Exon skipping events across known transcript of Ensembl for ZNF609 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
Top |
Gene isoform structures and expression levels for ZNF609 |
| Expression levels of gene isoforms across TCGA. |
 |
| Expression levels of gene isoforms across GTEx. |
 |
Top |
Exon skipping events with PSIs in TCGA for ZNF609 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_122793 | 15 | 64915025:64915251:64962544:64962632:64966114:64966970 | 64962544:64962632 | ENSG00000180357.5 | ENST00000326648.3 |
| exon_skip_122794 | 15 | 64962544:64962632:64966114:64968455:64970314:64970681 | 64966114:64968455 | ENSG00000180357.5 | ENST00000326648.3 |
| exon_skip_122796 | 15 | 64972844:64973061:64973507:64973586:64973890:64978264 | 64973507:64973586 | ENSG00000180357.5 | ENST00000326648.3 |
| PSI values of skipped exons in TCGA. |
 |
Top |
Exon skipping events with PSIs in GTEx for ZNF609 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_122793 | 15 | 64915025:64915251:64962544:64962632:64966114:64966970 | 64962544:64962632 | ENSG00000180357.5 | ENST00000326648.3 |
| exon_skip_122794 | 15 | 64962544:64962632:64966114:64968455:64970314:64970681 | 64966114:64968455 | ENSG00000180357.5 | ENST00000326648.3 |
| exon_skip_122796 | 15 | 64972844:64973061:64973507:64973586:64973890:64978264 | 64973507:64973586 | ENSG00000180357.5 | ENST00000326648.3 |
| PSI values of skipped exons in GTEx. |
 |
| * Skipped exon sequences. |
Top |
Open reading frame (ORF) annotation in the exon skipping event for ZNF609 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000326648 | 64973507 | 64973586 | 3UTR-3CDS |
| ENST00000326648 | 64962544 | 64962632 | Frame-shift |
| ENST00000326648 | 64966114 | 64968455 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000326648 | 64973507 | 64973586 | 3UTR-3CDS |
| ENST00000326648 | 64962544 | 64962632 | Frame-shift |
| ENST00000326648 | 64966114 | 64968455 | Frame-shift |
Top |
Infer the effects of exon skipping event on protein functional features for ZNF609 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
 |
| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
Top |
SNVs in the skipped exons for ZNF609 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
 |
| - Differential PSIs between mutated versus non-mutated samples. |
ZNF609_COAD_exon_skip_122794_psi_boxplot.png |
ZNF609_ESCA_exon_skip_122794_psi_boxplot.png |
ZNF609_LIHC_exon_skip_122794_psi_boxplot.png |
ZNF609_LUAD_exon_skip_122794_psi_boxplot.png |
ZNF609_STAD_exon_skip_122794_psi_boxplot.png |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| PRAD | TCGA-KK-A59V-01 | exon_skip_122794 | 64966115 | 64968455 | 64966285 | 64966285 | Frame_Shift_Del | G | - | p.R411fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_122794 | 64966115 | 64968455 | 64966317 | 64966317 | Frame_Shift_Del | C | - | p.P422fs |
| UCEC | TCGA-A5-A0G9-01 | exon_skip_122794 | 64966115 | 64968455 | 64966525 | 64966525 | Frame_Shift_Del | C | - | p.S491fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_122794 | 64966115 | 64968455 | 64966717 | 64966717 | Frame_Shift_Del | A | - | p.Q555fs |
| COAD | TCGA-F4-6570-01 | exon_skip_122794 | 64966115 | 64968455 | 64966750 | 64966750 | Frame_Shift_Del | C | - | p.T566fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_122794 | 64966115 | 64968455 | 64966836 | 64966836 | Frame_Shift_Del | G | - | p.G595fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_122794 | 64966115 | 64968455 | 64966890 | 64966890 | Frame_Shift_Del | C | - | p.P613fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_122794 | 64966115 | 64968455 | 64966921 | 64966921 | Frame_Shift_Del | C | - | p.A623fs |
| LIHC | TCGA-BC-A3KG-01 | exon_skip_122794 | 64966115 | 64968455 | 64967032 | 64967032 | Frame_Shift_Del | C | - | p.A660fs |
| COAD | TCGA-AU-6004-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967247 | Frame_Shift_Del | A | - | p.D731fs |
| COAD | TCGA-G4-6628-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967247 | Frame_Shift_Del | A | - | p.D731fs |
| ESCA | TCGA-L5-A4OI-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967247 | Frame_Shift_Del | A | - | p.K734fs |
| ESCA | TCGA-L5-A4OI-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967247 | Frame_Shift_Del | A | - | p.K735fs |
| UCEC | TCGA-B5-A0K9-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967247 | Frame_Shift_Del | A | - | p.K732fs |
| UCEC | TCGA-D1-A0ZO-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967247 | Frame_Shift_Del | A | - | p.K732fs |
| KIRC | TCGA-BP-5199-01 | exon_skip_122794 | 64966115 | 64968455 | 64967277 | 64967280 | Frame_Shift_Del | GAAA | - | p.741_742del |
| KIRC | TCGA-BP-5199-01 | exon_skip_122794 | 64966115 | 64968455 | 64967277 | 64967280 | Frame_Shift_Del | GAAA | - | p.ES742fs |
| UCEC | TCGA-A5-A0G9-01 | exon_skip_122794 | 64966115 | 64968455 | 64967390 | 64967390 | Frame_Shift_Del | C | - | p.D779fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_122794 | 64966115 | 64968455 | 64967994 | 64967994 | Frame_Shift_Del | C | - | p.P982fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_122794 | 64966115 | 64968455 | 64967994 | 64967994 | Frame_Shift_Del | C | - | p.P982fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_122796 | 64973508 | 64973586 | 64973567 | 64973567 | Frame_Shift_Del | C | - | p.P1409fs |
| LIHC | TCGA-BC-A112-01 | exon_skip_122794 | 64966115 | 64968455 | 64966950 | 64966951 | Frame_Shift_Ins | - | A | p.K633fs |
| ESCA | TCGA-VR-A8ET-01 | exon_skip_122794 | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K734fs |
| TGCT | TCGA-2G-AAGM-01 | exon_skip_122794 | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.D731fs |
| TGCT | TCGA-2G-AAGM-01 | exon_skip_122794 | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.EK731fs |
| UCEC | TCGA-AP-A05H-01 | exon_skip_122794 | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.D731fs |
| UCEC | TCGA-AX-A06H-01 | exon_skip_122794 | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.D731fs |
| STAD | TCGA-BR-8368-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967248 | Frame_Shift_Ins | - | A | p.D731fs |
| STAD | TCGA-HU-A4GF-01 | exon_skip_122794 | 64966115 | 64968455 | 64967247 | 64967248 | Frame_Shift_Ins | - | A | p.D731fs |
| LUAD | TCGA-44-2656-01 | exon_skip_122794 | 64966115 | 64968455 | 64967993 | 64967994 | Frame_Shift_Ins | - | C | p.V980fs |
| PAAD | TCGA-IB-7651-01 | exon_skip_122793 | 64962545 | 64962632 | 64962610 | 64962610 | Nonsense_Mutation | C | T | p.R347* |
| PAAD | TCGA-IB-7651-01 | exon_skip_122793 | 64962545 | 64962632 | 64962610 | 64962610 | Nonsense_Mutation | C | T | p.R347X |
| CESC | TCGA-Q1-A6DT-01 | exon_skip_122794 | 64966115 | 64968455 | 64966714 | 64966714 | Nonsense_Mutation | C | G | p.S554* |
| ESCA | TCGA-VR-A8ET-01 | exon_skip_122794 | 64966115 | 64968455 | 64966761 | 64966761 | Nonsense_Mutation | C | T | p.R570* |
| ESCA | TCGA-VR-A8ET-01 | exon_skip_122794 | 64966115 | 64968455 | 64966761 | 64966761 | Nonsense_Mutation | C | T | p.R570X |
| UCEC | TCGA-AP-A056-01 | exon_skip_122794 | 64966115 | 64968455 | 64966761 | 64966761 | Nonsense_Mutation | C | T | p.R570* |
| UCEC | TCGA-D1-A167-01 | exon_skip_122794 | 64966115 | 64968455 | 64968078 | 64968078 | Nonsense_Mutation | C | T | p.Q1009* |
| CESC | TCGA-JW-A5VL-01 | exon_skip_122796 | 64973508 | 64973586 | 64973556 | 64973556 | Nonsense_Mutation | C | G | p.S1404* |
| CHOL | TCGA-W5-AA38-01 | exon_skip_122794 | 64966115 | 64968455 | 64968457 | 64968457 | Splice_Site | T | G | . |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-VR-A8ET-01 |
| Cancer type: ESCA | |
| ESID: exon_skip_122794 | |
| Skipped exon start: 64966115 | |
| Skipped exon end: 64968455 | |
| Mutation start: 64967246 | |
| Mutation end: 64967247 | |
| Mutation type: Frame_Shift_Ins | |
| Reference seq: - | |
| Mutation seq: A | |
| AAchange: p.K734fs | |
| Sample: TCGA-VR-A8ET-01 |
| Cancer type: ESCA | |
| ESID: exon_skip_122794 | |
| Skipped exon start: 64966115 | |
| Skipped exon end: 64968455 | |
| Mutation start: 64966761 | |
| Mutation end: 64966761 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.R570X | |
| Sample: TCGA-VR-A8ET-01 |
| Cancer type: ESCA | |
| ESID: exon_skip_122794 | |
| Skipped exon start: 64966115 | |
| Skipped exon end: 64968455 | |
| Mutation start: 64966761 | |
| Mutation end: 64966761 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.R570* | |
exon_skip_122794_ESCA_TCGA-VR-A8ET-01.png | |
 | Sample: TCGA-BR-8368-01 |
| Cancer type: STAD | |
| ESID: exon_skip_122794 | |
| Skipped exon start: 64966115 | |
| Skipped exon end: 64968455 | |
| Mutation start: 64967247 | |
| Mutation end: 64967248 | |
| Mutation type: Frame_Shift_Ins | |
| Reference seq: - | |
| Mutation seq: A | |
| AAchange: p.D731fs | |
exon_skip_122794_STAD_TCGA-BR-8368-01.png | |
exon_skip_300158_STAD_TCGA-BR-8368-01.png | |
exon_skip_336630_STAD_TCGA-BR-8368-01.png | |
exon_skip_451867_STAD_TCGA-BR-8368-01.png | |
exon_skip_469307_STAD_TCGA-BR-8368-01.png | |
exon_skip_469308_STAD_TCGA-BR-8368-01.png | |
exon_skip_469318_STAD_TCGA-BR-8368-01.png | |
exon_skip_469321_STAD_TCGA-BR-8368-01.png | |
exon_skip_481431_STAD_TCGA-BR-8368-01.png | |
exon_skip_510143_STAD_TCGA-BR-8368-01.png | |
exon_skip_61768_STAD_TCGA-BR-8368-01.png | |
 | Sample: TCGA-HU-A4GF-01 |
| Cancer type: STAD | |
| ESID: exon_skip_122794 | |
| Skipped exon start: 64966115 | |
| Skipped exon end: 64968455 | |
| Mutation start: 64967247 | |
| Mutation end: 64967248 | |
| Mutation type: Frame_Shift_Ins | |
| Reference seq: - | |
| Mutation seq: A | |
| AAchange: p.D731fs | |
exon_skip_122794_STAD_TCGA-HU-A4GF-01.png | |
exon_skip_350768_STAD_TCGA-HU-A4GF-01.png | |
exon_skip_494752_STAD_TCGA-HU-A4GF-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| JHUEM2_ENDOMETRIUM | 64966115 | 64968455 | 64966957 | 64966957 | Frame_Shift_Del | A | - | p.E635fs |
| SNUC4_LARGE_INTESTINE | 64966115 | 64968455 | 64966990 | 64966990 | Frame_Shift_Del | A | - | p.E646fs |
| AN3CA_ENDOMETRIUM | 64966115 | 64968455 | 64967689 | 64967689 | Frame_Shift_Del | T | - | p.L879fs |
| MHHPREB1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967689 | 64967689 | Frame_Shift_Del | T | - | p.L879fs |
| SNU1040_LARGE_INTESTINE | 64966115 | 64968455 | 64967689 | 64967689 | Frame_Shift_Del | T | - | p.L879fs |
| HEC6_ENDOMETRIUM | 64966115 | 64968455 | 64967694 | 64967694 | Frame_Shift_Del | C | - | p.P882fs |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 64966115 | 64968455 | 64967694 | 64967694 | Frame_Shift_Del | C | - | p.P882fs |
| KM12_LARGE_INTESTINE | 64966115 | 64968455 | 64967694 | 64967694 | Frame_Shift_Del | C | - | p.P882fs |
| LS411N_LARGE_INTESTINE | 64966115 | 64968455 | 64967831 | 64967831 | Frame_Shift_Del | A | - | p.T926fs |
| CMLT1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967994 | 64967994 | Frame_Shift_Del | C | - | p.P982fs |
| SNGM_ENDOMETRIUM | 64966115 | 64968455 | 64967994 | 64967994 | Frame_Shift_Del | C | - | p.P982fs |
| CTV1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967994 | 64967994 | Frame_Shift_Del | C | - | p.P982fs |
| GP2D_LARGE_INTESTINE | 64973508 | 64973586 | 64973567 | 64973567 | Frame_Shift_Del | C | - | p.P1409fs |
| GP5D_LARGE_INTESTINE | 64973508 | 64973586 | 64973567 | 64973567 | Frame_Shift_Del | C | - | p.P1409fs |
| HEC265_ENDOMETRIUM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| EN_ENDOMETRIUM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| CAPAN2_PANCREAS | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| CAS1_CENTRAL_NERVOUS_SYSTEM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| CL40_LARGE_INTESTINE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| GOS3_CENTRAL_NERVOUS_SYSTEM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| HMEL_BREAST | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| HS675T_FIBROBLAST | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| HS751T_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| JEKO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| KCL22_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| KP3_PANCREAS | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| KYSE180_OESOPHAGUS | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| LNZ308_CENTRAL_NERVOUS_SYSTEM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| MDAMB361_BREAST | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| MFE280_ENDOMETRIUM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| NCIH2110_LUNG | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| RPMI8402_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| SCABER_URINARY_TRACT | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| SNU1_STOMACH | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| SNU201_CENTRAL_NERVOUS_SYSTEM | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| SW948_LARGE_INTESTINE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| TC71_BONE | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| TE4_OESOPHAGUS | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| TIG3TD_FIBROBLAST | 64966115 | 64968455 | 64967246 | 64967247 | Frame_Shift_Ins | - | A | p.K732fs |
| DV90_LUNG | 64966115 | 64968455 | 64967688 | 64967689 | Frame_Shift_Ins | - | T | p.L879fs |
| JAR_PLACENTA | 64962545 | 64962632 | 64962562 | 64962562 | Missense_Mutation | G | T | p.V331L |
| HT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64966150 | 64966150 | Missense_Mutation | G | T | p.R366L |
| 22RV1_PROSTATE | 64966115 | 64968455 | 64966179 | 64966179 | Missense_Mutation | C | T | p.R376C |
| PATU8988S_PANCREAS | 64966115 | 64968455 | 64966226 | 64966226 | Missense_Mutation | C | A | p.D391E |
| HEC1_ENDOMETRIUM | 64966115 | 64968455 | 64966282 | 64966282 | Missense_Mutation | G | A | p.R410H |
| HT115_LARGE_INTESTINE | 64966115 | 64968455 | 64966284 | 64966284 | Missense_Mutation | C | T | p.R411W |
| DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64966378 | 64966378 | Missense_Mutation | A | G | p.N442S |
| BICR18_UPPER_AERODIGESTIVE_TRACT | 64966115 | 64968455 | 64966378 | 64966378 | Missense_Mutation | A | G | p.N442S |
| SNU1_STOMACH | 64966115 | 64968455 | 64966447 | 64966447 | Missense_Mutation | C | G | p.T465S |
| SNU5_STOMACH | 64966115 | 64968455 | 64966447 | 64966447 | Missense_Mutation | C | G | p.T465S |
| MHHNB11_AUTONOMIC_GANGLIA | 64966115 | 64968455 | 64966483 | 64966483 | Missense_Mutation | G | T | p.G477V |
| UO31_KIDNEY | 64966115 | 64968455 | 64966501 | 64966501 | Missense_Mutation | C | T | p.T483I |
| SNGM_ENDOMETRIUM | 64966115 | 64968455 | 64966530 | 64966530 | Missense_Mutation | G | A | p.V493I |
| ME180_CERVIX | 64966115 | 64968455 | 64966530 | 64966530 | Missense_Mutation | G | A | p.V493I |
| SF767_CENTRAL_NERVOUS_SYSTEM | 64966115 | 64968455 | 64966530 | 64966530 | Missense_Mutation | G | A | p.V493I |
| EN_ENDOMETRIUM | 64966115 | 64968455 | 64966570 | 64966570 | Missense_Mutation | A | G | p.Y506C |
| NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64966633 | 64966633 | Missense_Mutation | C | T | p.P527L |
| HEC50B_ENDOMETRIUM | 64966115 | 64968455 | 64966642 | 64966642 | Missense_Mutation | A | G | p.D530G |
| PF382_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64966666 | 64966666 | Missense_Mutation | A | G | p.E538G |
| MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64966767 | 64966767 | Missense_Mutation | G | A | p.V572I |
| NCIH2291_LUNG | 64966115 | 64968455 | 64966816 | 64966816 | Missense_Mutation | T | A | p.L588H |
| IGROV1_OVARY | 64966115 | 64968455 | 64966861 | 64966861 | Missense_Mutation | C | T | p.A603V |
| SCC25_UPPER_AERODIGESTIVE_TRACT | 64966115 | 64968455 | 64966935 | 64966935 | Missense_Mutation | G | C | p.E628Q |
| COLO792_SKIN | 64966115 | 64968455 | 64966998 | 64966998 | Missense_Mutation | C | T | p.P649S |
| MEWO_SKIN | 64966115 | 64968455 | 64966999 | 64966999 | Missense_Mutation | C | T | p.P649L |
| UACC893_BREAST | 64966115 | 64968455 | 64967037 | 64967037 | Missense_Mutation | G | A | p.A662T |
| SNU1040_LARGE_INTESTINE | 64966115 | 64968455 | 64967070 | 64967070 | Missense_Mutation | A | G | p.T673A |
| DOTC24510_CERVIX | 64966115 | 64968455 | 64967255 | 64967255 | Missense_Mutation | G | C | p.K734N |
| DAUDI_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967261 | 64967261 | Missense_Mutation | A | C | p.E736D |
| UMUC14_URINARY_TRACT | 64966115 | 64968455 | 64967313 | 64967313 | Missense_Mutation | G | C | p.E754Q |
| LS411N_LARGE_INTESTINE | 64966115 | 64968455 | 64967353 | 64967353 | Missense_Mutation | G | A | p.G767E |
| KARPAS45_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967457 | 64967457 | Missense_Mutation | G | A | p.A802T |
| DMS114_LUNG | 64966115 | 64968455 | 64967631 | 64967631 | Missense_Mutation | G | C | p.D860H |
| C33A_CERVIX | 64966115 | 64968455 | 64967694 | 64967694 | Missense_Mutation | C | T | p.P881S |
| RL952_ENDOMETRIUM | 64966115 | 64968455 | 64967694 | 64967694 | Missense_Mutation | C | T | p.P881S |
| MEWO_SKIN | 64966115 | 64968455 | 64967697 | 64967697 | Missense_Mutation | C | T | p.P882S |
| LOXIMVI_SKIN | 64966115 | 64968455 | 64967782 | 64967782 | Missense_Mutation | C | T | p.A910V |
| GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64967824 | 64967824 | Missense_Mutation | T | C | p.L924P |
| NCIH1573_LUNG | 64966115 | 64968455 | 64967838 | 64967838 | Missense_Mutation | G | A | p.D929N |
| CW2_LARGE_INTESTINE | 64966115 | 64968455 | 64967842 | 64967842 | Missense_Mutation | A | C | p.E930A |
| 647V_URINARY_TRACT | 64966115 | 64968455 | 64967901 | 64967901 | Missense_Mutation | G | A | p.E950K |
| NCIH1755_LUNG | 64966115 | 64968455 | 64967998 | 64967998 | Missense_Mutation | C | G | p.P982R |
| OCUBM_BREAST | 64966115 | 64968455 | 64967998 | 64967998 | Missense_Mutation | C | G | p.P982R |
| PANC0327_PANCREAS | 64966115 | 64968455 | 64968001 | 64968001 | Missense_Mutation | A | G | p.Y983C |
| MDAMB415_BREAST | 64966115 | 64968455 | 64968122 | 64968122 | Missense_Mutation | G | C | p.K1023N |
| CP66MEL_SKIN | 64966115 | 64968455 | 64968183 | 64968183 | Missense_Mutation | C | T | p.P1044S |
| NBTU110_AUTONOMIC_GANGLIA | 64966115 | 64968455 | 64968184 | 64968184 | Missense_Mutation | C | T | p.P1044L |
| RCK8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64968184 | 64968184 | Missense_Mutation | C | T | p.P1044L |
| SCC3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64968184 | 64968184 | Missense_Mutation | C | T | p.P1044L |
| DG75_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64968198 | 64968198 | Missense_Mutation | A | G | p.T1049A |
| NCIH2135_LUNG | 64966115 | 64968455 | 64968207 | 64968207 | Missense_Mutation | A | G | p.K1052E |
| TE125T_FIBROBLAST | 64966115 | 64968455 | 64968210 | 64968210 | Missense_Mutation | G | A | p.A1053T |
| RKN_SOFT_TISSUE | 64966115 | 64968455 | 64968270 | 64968270 | Missense_Mutation | G | A | p.D1073N |
| KMS11_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64968280 | 64968280 | Missense_Mutation | A | T | p.K1076I |
| HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64968402 | 64968402 | Missense_Mutation | G | A | p.G1117S |
| PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 64966115 | 64968455 | 64968402 | 64968402 | Missense_Mutation | G | A | p.G1117S |
| HEC1_ENDOMETRIUM | 64966115 | 64968455 | 64966761 | 64966761 | Nonsense_Mutation | C | T | p.R570* |
| GSS_STOMACH | 64966115 | 64968455 | 64968168 | 64968168 | Nonsense_Mutation | G | T | p.E1039* |
Top |
Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for ZNF609 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
Top |
Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF609 |
Top |
Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for ZNF609 |
Top |
RelatedDrugs for ZNF609 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for ZNF609 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|