ExonSkipDB: functional annotation of exon skipping event in human

Gene summary for MPP7

Gene summary

Gene information	Gene symbol	MPP7
	Gene ID	143098
	Gene name	membrane palmitoylated protein 7
	Synonyms	-
	Cytomap	10p12.1
	Type of gene	protein-coding
	Description	MAGUK p55 subfamily member 7membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
	Modification date	20180522
	UniProtAcc	Q5T2T1
	Context	PubMed: MPP7 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID)

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
MPP7	GO:0031334	positive regulation of protein complex assembly	17237226
MPP7	GO:0070830	bicellular tight junction assembly	17332497

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Exon skipping events across known transcript of Ensembl for MPP7 from UCSC genome browser

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Gene isoform structures and expression levels for MPP7

Expression levels of gene isoforms across TCGA.

Expression levels of gene isoforms across GTEx.

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Exon skipping events with PSIs in TCGA for MPP7

Information of exkip skipping event in TCGA.

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENSG00000150054.14	ENST00000445954.2
exon_skip_48441	10	28348578:28348672:28358700:28358781:28378599:28378770	28358700:28358781	ENSG00000150054.14	ENST00000375719.3,ENST00000540098.1,ENST00000337532.5,ENST00000375732.1,ENST00000441595.2,ENST00000496637.2,ENST00000445954.2
exon_skip_48444	10	28358700:28358781:28378599:28378770:28408579:28408644	28378599:28378770	ENSG00000150054.14	ENST00000375719.3,ENST00000540098.1,ENST00000337532.5,ENST00000375732.1,ENST00000441595.2,ENST00000496637.2,ENST00000445954.2
exon_skip_48445	10	28420488:28420620:28436411:28436492:28438910:28438988	28436411:28436492	ENSG00000150054.14	ENST00000375719.3,ENST00000540098.1,ENST00000337532.5,ENST00000375732.1,ENST00000496637.2,ENST00000445954.2,ENST00000474731.1,ENST00000481244.1
exon_skip_48448	10	28438910:28438988:28491081:28491200:28527496:28527629	28491081:28491200	ENSG00000150054.14	ENST00000375719.3,ENST00000540098.1,ENST00000337532.5,ENST00000375732.1,ENST00000496637.2,ENST00000481244.1

PSI values of skipped exons in TCGA.

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Exon skipping events with PSIs in GTEx for MPP7

Information of exkip skipping event in GTEx

Exon skip ID	chr	Exons involved in exon skipping	Skipped exon	ENSG	ENSTs
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENSG00000150054.14	ENST00000445954.2
exon_skip_48444	10	28358700:28358781:28378599:28378770:28408579:28408644	28378599:28378770	ENSG00000150054.14	ENST00000375732.1,ENST00000337532.5,ENST00000496637.2,ENST00000540098.1,ENST00000375719.3,ENST00000441595.2,ENST00000445954.2
exon_skip_48445	10	28420488:28420620:28436411:28436492:28438910:28438988	28436411:28436492	ENSG00000150054.14	ENST00000375732.1,ENST00000337532.5,ENST00000496637.2,ENST00000540098.1,ENST00000375719.3,ENST00000445954.2,ENST00000481244.1,ENST00000474731.1
exon_skip_48448	10	28438910:28438988:28491081:28491200:28527496:28527629	28491081:28491200	ENSG00000150054.14	ENST00000375732.1,ENST00000337532.5,ENST00000496637.2,ENST00000540098.1,ENST00000375719.3,ENST00000481244.1
exon_skip_48451	10	28527496:28527664:28543702:28543805:28569028:28569069	28543702:28543805	ENSG00000150054.14	ENST00000337532.5,ENST00000375719.3

PSI values of skipped exons in GTEx.

* Skipped exon sequences.

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Open reading frame (ORF) annotation in the exon skipping event for MPP7

Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000337532	28491081	28491200	Frame-shift
ENST00000375719	28491081	28491200	Frame-shift
ENST00000375732	28491081	28491200	Frame-shift
ENST00000337532	28358700	28358781	In-frame
ENST00000375719	28358700	28358781	In-frame
ENST00000375732	28358700	28358781	In-frame
ENST00000337532	28378599	28378770	In-frame
ENST00000375719	28378599	28378770	In-frame
ENST00000375732	28378599	28378770	In-frame
ENST00000337532	28436411	28436492	In-frame
ENST00000375719	28436411	28436492	In-frame
ENST00000375732	28436411	28436492	In-frame

Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms.

ENST	Start of skipped exon	End of skipped exon	ORF
ENST00000337532	28543702	28543805	3UTR-3UTR
ENST00000375719	28543702	28543805	3UTR-3UTR
ENST00000337532	28491081	28491200	Frame-shift
ENST00000375719	28491081	28491200	Frame-shift
ENST00000375732	28491081	28491200	Frame-shift
ENST00000337532	28378599	28378770	In-frame
ENST00000375719	28378599	28378770	In-frame
ENST00000375732	28378599	28378770	In-frame
ENST00000337532	28436411	28436492	In-frame
ENST00000375719	28436411	28436492	In-frame
ENST00000375732	28436411	28436492	In-frame

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Infer the effects of exon skipping event on protein functional features for MPP7

Exon skipping at the protein sequence level and followed lost functional features.
* Click on the image to enlarge it in a new window.

Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000337532	5097	576	28436411	28436492	512	592	78	105
ENST00000375719	2107	576	28436411	28436492	590	670	78	105
ENST00000375732	5080	576	28436411	28436492	495	575	78	105
ENST00000337532	5097	576	28378599	28378770	1230	1400	317	374
ENST00000375719	2107	576	28378599	28378770	1308	1478	317	374
ENST00000375732	5080	576	28378599	28378770	1213	1383	317	374
ENST00000337532	5097	576	28358700	28358781	1401	1481	374	401
ENST00000375719	2107	576	28358700	28358781	1479	1559	374	401
ENST00000375732	5080	576	28358700	28358781	1384	1464	374	401

Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases.

ENST	Length of mRNA	Length of AA seq.	Genomic start	Genomic end	mRNA start	mRNA end	AA start	AA end
ENST00000337532	5097	576	28436411	28436492	512	592	78	105
ENST00000375719	2107	576	28436411	28436492	590	670	78	105
ENST00000375732	5080	576	28436411	28436492	495	575	78	105
ENST00000337532	5097	576	28378599	28378770	1230	1400	317	374
ENST00000375719	2107	576	28378599	28378770	1308	1478	317	374
ENST00000375732	5080	576	28378599	28378770	1213	1383	317	374

Lost protein functional features of individual exon skipping events in TCGA.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
Q5T2T1	78	105	1	125	Alternative sequence	ID=VSP_056065;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:14702039;Dbxref=PMID:14702039
Q5T2T1	78	105	1	125	Alternative sequence	ID=VSP_056065;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:14702039;Dbxref=PMID:14702039
Q5T2T1	78	105	1	125	Alternative sequence	ID=VSP_056065;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:14702039;Dbxref=PMID:14702039
Q5T2T1	78	105	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	78	105	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	78	105	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	78	105	67	122	Domain	Note=L27 2;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00365
Q5T2T1	78	105	67	122	Domain	Note=L27 2;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00365
Q5T2T1	78	105	67	122	Domain	Note=L27 2;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00365
Q5T2T1	78	105	72	84	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	72	84	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	72	84	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	90	98	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	90	98	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	90	98	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	102	115	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	102	115	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	102	115	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	95	95	Mutagenesis	Note=Does not affect the interaction with DLG1. L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17332497;Dbxref=PMID:17332497
Q5T2T1	78	105	95	95	Mutagenesis	Note=Does not affect the interaction with DLG1. L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17332497;Dbxref=PMID:17332497
Q5T2T1	78	105	95	95	Mutagenesis	Note=Does not affect the interaction with DLG1. L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17332497;Dbxref=PMID:17332497
Q5T2T1	317	374	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	317	374	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	317	374	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	317	374	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	317	374	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	317	374	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	317	374	322	322	Natural variant	ID=VAR_039110;Note=K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:14702039,ECO:0000269\|PubMed:15489334,ECO:0000269\|Ref.3;Dbxref=dbSNP:rs2997211,PMID:14702039,PMID:15489334
Q5T2T1	317	374	322	322	Natural variant	ID=VAR_039110;Note=K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:14702039,ECO:0000269\|PubMed:15489334,ECO:0000269\|Ref.3;Dbxref=dbSNP:rs2997211,PMID:14702039,PMID:15489334
Q5T2T1	317	374	322	322	Natural variant	ID=VAR_039110;Note=K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:14702039,ECO:0000269\|PubMed:15489334,ECO:0000269\|Ref.3;Dbxref=dbSNP:rs2997211,PMID:14702039,PMID:15489334
Q5T2T1	374	401	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	374	401	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	374	401	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	374	401	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	374	401	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	374	401	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100

Lost protein functional features of individual exon skipping events in GTEx.

UniProt acc.	Start of exon skipping (AA)	End of exon skipping (AA)	Protein feature start (AA)	Protein feature end (AA)	Category of protein feature	Description of feature
Q5T2T1	78	105	1	125	Alternative sequence	ID=VSP_056065;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:14702039;Dbxref=PMID:14702039
Q5T2T1	78	105	1	125	Alternative sequence	ID=VSP_056065;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:14702039;Dbxref=PMID:14702039
Q5T2T1	78	105	1	125	Alternative sequence	ID=VSP_056065;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303\|PubMed:14702039;Dbxref=PMID:14702039
Q5T2T1	78	105	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	78	105	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	78	105	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	78	105	67	122	Domain	Note=L27 2;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00365
Q5T2T1	78	105	67	122	Domain	Note=L27 2;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00365
Q5T2T1	78	105	67	122	Domain	Note=L27 2;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00365
Q5T2T1	78	105	72	84	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	72	84	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	72	84	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	90	98	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	90	98	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	90	98	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	102	115	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	102	115	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	102	115	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3LRA
Q5T2T1	78	105	95	95	Mutagenesis	Note=Does not affect the interaction with DLG1. L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17332497;Dbxref=PMID:17332497
Q5T2T1	78	105	95	95	Mutagenesis	Note=Does not affect the interaction with DLG1. L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17332497;Dbxref=PMID:17332497
Q5T2T1	78	105	95	95	Mutagenesis	Note=Does not affect the interaction with DLG1. L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17332497;Dbxref=PMID:17332497
Q5T2T1	317	374	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	317	374	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	317	374	1	576	Chain	ID=PRO_0000320027;Note=MAGUK p55 subfamily member 7
Q5T2T1	317	374	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	317	374	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	317	374	368	560	Domain	Note=Guanylate kinase-like;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00100
Q5T2T1	317	374	322	322	Natural variant	ID=VAR_039110;Note=K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:14702039,ECO:0000269\|PubMed:15489334,ECO:0000269\|Ref.3;Dbxref=dbSNP:rs2997211,PMID:14702039,PMID:15489334
Q5T2T1	317	374	322	322	Natural variant	ID=VAR_039110;Note=K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:14702039,ECO:0000269\|PubMed:15489334,ECO:0000269\|Ref.3;Dbxref=dbSNP:rs2997211,PMID:14702039,PMID:15489334
Q5T2T1	317	374	322	322	Natural variant	ID=VAR_039110;Note=K->R;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269\|PubMed:14702039,ECO:0000269\|PubMed:15489334,ECO:0000269\|Ref.3;Dbxref=dbSNP:rs2997211,PMID:14702039,PMID:15489334

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SNVs in the skipped exons for MPP7

- Lollipop plot for presenting exon skipping associated SNVs.
* Click on the image to enlarge it in a new window.

- Differential PSIs between mutated versus non-mutated samples.

- Non-synonymous mutations located in the skipped exons in TCGA.

Cancer type	Sample	ESID	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
LIHC	TCGA-DD-A1EG-01	exon_skip_48448	28491082	28491200	28491102	28491102	Frame_Shift_Del	T	-	p.S46fs
LIHC	TCGA-DD-A3A0-01	exon_skip_48448	28491082	28491200	28491102	28491102	Frame_Shift_Del	T	-	p.S46fs
LIHC	TCGA-G3-A3CJ-01	exon_skip_48448	28491082	28491200	28491102	28491102	Frame_Shift_Del	T	-	p.S46fs
GBM	TCGA-27-2521-01		28378600	28378770	28378639	28378639	Nonsense_Mutation	G	A	p.R362*
STAD	TCGA-CG-5721-01	exon_skip_48441	28358701	28358781	28358700	28358700	Splice_Site	C	T	.
STAD	TCGA-CG-5721-01	exon_skip_48441	28358701	28358781	28358700	28358700	Splice_Site	C	T	p.H402_splice
UCEC	TCGA-AP-A051-01	exon_skip_48441	28358701	28358781	28358700	28358700	Splice_Site	C	T	e12+1
BLCA	TCGA-E7-A3Y1-01	exon_skip_48441	28358701	28358781	28358781	28358782	Splice_Site	CC	AA	p.G375_splice

- Depth of coverage in the three exons composing exon skipping event

Depth of coverage in three exons

Mutation description

- Non-synonymous mutations located in the skipped exons in CCLE.

Sample	Skipped exon start	Skipped exon end	Mutation start	Mutation end	Mutation type	Reference seq	Mutation seq	AAchange
SW982_SOFT_TISSUE	28358701	28358781	28358748	28358748	Missense_Mutation	C	T	p.R386Q
COLO741_SKIN	28378600	28378770	28378638	28378638	Missense_Mutation	C	T	p.R362Q
HEC108_ENDOMETRIUM	28378600	28378770	28378674	28378674	Missense_Mutation	T	C	p.D350G
EN_ENDOMETRIUM	28378600	28378770	28378710	28378710	Missense_Mutation	T	C	p.Y338C
COLO320_LARGE_INTESTINE	28491082	28491200	28491179	28491179	Missense_Mutation	G	C	p.A20G
DMS53_LUNG	28491082	28491200	28491179	28491179	Missense_Mutation	G	C	p.A20G
GAK_SKIN	28491082	28491200	28491179	28491179	Missense_Mutation	G	C	p.A20G
NCIH1694_LUNG	28491082	28491200	28491179	28491179	Missense_Mutation	G	C	p.A20G
YD8_UPPER_AERODIGESTIVE_TRACT	28358701	28358781	28358701	28358701	Splice_Site	G	A	p.H402Y
NCIH2452_PLEURA	28358701	28358781	28358701	28358701	Splice_Site	G	A	p.H402Y
PC9_LUNG	28436412	28436492	28436412	28436412	Splice_Site	C	A	p.K105N

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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MPP7

sQTL information located at the skipped exons.

Exon skip ID	Chromosome	Three exons	Skippped exon	ENST	Cancer type	SNP id	Location	DNA change (ref/var)	P-value
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENST00000445954.2	LUAD	rs76671899	chr10:28346629	A/AGT	2.91e-03
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENST00000445954.2	OV	rs12217744	chr10:28346584	G/A	6.79e-06
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENST00000445954.2	OV	rs76671899	chr10:28346629	A/AGT	3.42e-05
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENST00000445954.2	THCA	rs76671899	chr10:28346629	A/AGT	3.88e-08
exon_skip_48440	10	28345525:28345552:28346574:28346778:28347423:28347532	28346574:28346778	ENST00000445954.2	THCA	rs12217744	chr10:28346584	G/A	1.18e-07

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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MPP7

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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MPP7

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RelatedDrugs for MPP7

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for MPP7

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
MPP7	C0236969	Substance-Related Disorders	1	CTD_human

	Gene summary
	Gene structures and expression levels
	Exon skipping events with PSIs in TCGA
	Exon skipping events with PSIs in GTEx
	Open reading frame (ORF) annotation in the exon skipping event
	Exon skipping events in the canonical protein sequence
	SNVs in the skipped exons with depth of coverage
	Splicing Quantitative Trait Loci (sQTLs) in the skipped exons
	Splicing Quantitative Trait Methylation (sQTM) in the skipped exon
	Related drugs with this gene
	Related diseases with this gene

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