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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for CIRBP |
 Gene summary |
| Gene information | Gene symbol | CIRBP | Gene ID | 1153 |
| Gene name | cold inducible RNA binding protein | |
| Synonyms | CIRP | |
| Cytomap | 19p13.3 | |
| Type of gene | protein-coding | |
| Description | cold-inducible RNA-binding proteinA18 hnRNPglycine-rich RNA binding proteintesticular tissue protein Li 39 | |
| Modification date | 20180523 | |
| UniProtAcc | Q14011 | |
| Context | PubMed: CIRBP [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| CIRBP | GO:0009411 | response to UV | 11574538 |
| CIRBP | GO:0045727 | positive regulation of translation | 11574538 |
| CIRBP | GO:0048255 | mRNA stabilization | 11574538 |
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Exon skipping events across known transcript of Ensembl for CIRBP from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for CIRBP |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for CIRBP |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_300475 | 19 | 1261380:1261640:1264251:1264462:1270926:1271028 | 1264251:1264462 | ENSG00000099622.9 | ENST00000592051.1 |
| exon_skip_300483 | 19 | 1269330:1269406:1270878:1270881:1270926:1271035 | 1270878:1270881 | ENSG00000099622.9 | ENST00000588230.1,ENST00000586472.1 |
| exon_skip_300484 | 19 | 1269348:1269409:1269910:1269914:1270926:1271035 | 1269910:1269914 | ENSG00000099622.9 | ENST00000587896.1 |
| exon_skip_300485 | 19 | 1269354:1269409:1270865:1271035:1271138:1271245 | 1270865:1271035 | ENSG00000099622.9 | ENST00000590704.1,ENST00000589710.1,ENST00000589686.1 |
| exon_skip_300492 | 19 | 1269354:1269409:1270926:1271035:1271138:1271245 | 1270926:1271035 | ENSG00000099622.9 | ENST00000413636.2,ENST00000591659.1,ENST00000589235.1,ENST00000587323.1,ENST00000591055.1,ENST00000593128.1,ENST00000590347.1,ENST00000593283.1,ENST00000320936.5,ENST00000586636.1,ENST00000585914.1 |
| exon_skip_300493 | 19 | 1269354:1269409:1270926:1271035:1271327:1271360 | 1270926:1271035 | ENSG00000099622.9 | ENST00000587169.1,ENST00000593048.1,ENST00000444172.2,ENST00000591376.1,ENST00000592412.1 |
| exon_skip_300499 | 19 | 1270926:1271035:1271119:1271245:1271327:1271360 | 1271119:1271245 | ENSG00000099622.9 | ENST00000590171.1,ENST00000591097.1 |
| exon_skip_300500 | 19 | 1270926:1271035:1271138:1271245:1271327:1271360 | 1271138:1271245 | ENSG00000099622.9 | ENST00000413636.2,ENST00000588230.1,ENST00000591659.1,ENST00000589235.1,ENST00000587323.1,ENST00000586472.1,ENST00000585913.1,ENST00000589710.1,ENST00000589266.1,ENST00000588090.1,ENST00000586773.1,ENST00000591935.1,ENST00000585630.1,ENST00000588030.1,ENS |
| exon_skip_300501 | 19 | 1271138:1271245:1271327:1271364:1271549:1271631 | 1271327:1271364 | ENSG00000099622.9 | ENST00000413636.2 |
| exon_skip_300502 | 19 | 1271138:1271245:1271327:1271466:1271549:1271631 | 1271327:1271466 | ENSG00000099622.9 | ENST00000588230.1,ENST00000589235.1,ENST00000587323.1,ENST00000586472.1,ENST00000585913.1,ENST00000589710.1,ENST00000588090.1,ENST00000586773.1,ENST00000591935.1,ENST00000590171.1,ENST00000585630.1,ENST00000588030.1,ENST00000591097.1,ENST00000589660.1,ENS |
| exon_skip_300504 | 19 | 1271327:1271364:1271549:1271631:1271979:1272027 | 1271549:1271631 | ENSG00000099622.9 | ENST00000413636.2,ENST00000591055.1,ENST00000590347.1 |
| exon_skip_300514 | 19 | 1271449:1271466:1271549:1271631:1271979:1272027 | 1271549:1271631 | ENSG00000099622.9 | ENST00000588230.1,ENST00000587169.1,ENST00000589235.1,ENST00000587323.1,ENST00000586472.1,ENST00000585913.1,ENST00000590704.1,ENST00000593048.1,ENST00000589710.1,ENST00000444172.2,ENST00000591376.1,ENST00000588090.1,ENST00000586773.1,ENST00000593093.1,ENS |
| exon_skip_300534 | 19 | 1271979:1272050:1273492:1273714:1274305:1274362 | 1273492:1273714 | ENSG00000099622.9 | ENST00000585914.1 |
| exon_skip_300537 | 19 | 1271979:1272050:1273599:1273714:1274305:1274362 | 1273599:1273714 | ENSG00000099622.9 | ENST00000592234.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for CIRBP |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_300475 | 19 | 1261380:1261640:1264251:1264462:1270926:1271028 | 1264251:1264462 | ENSG00000099622.9 | ENST00000592051.1 |
| exon_skip_300483 | 19 | 1269330:1269406:1270878:1270881:1270926:1271035 | 1270878:1270881 | ENSG00000099622.9 | ENST00000588230.1,ENST00000586472.1 |
| exon_skip_300484 | 19 | 1269348:1269409:1269910:1269914:1270926:1271035 | 1269910:1269914 | ENSG00000099622.9 | ENST00000587896.1 |
| exon_skip_300485 | 19 | 1269354:1269409:1270865:1271035:1271138:1271245 | 1270865:1271035 | ENSG00000099622.9 | ENST00000589710.1,ENST00000590704.1,ENST00000589686.1 |
| exon_skip_300492 | 19 | 1269354:1269409:1270926:1271035:1271138:1271245 | 1270926:1271035 | ENSG00000099622.9 | ENST00000593128.1,ENST00000413636.2,ENST00000590347.1,ENST00000593283.1,ENST00000587323.1,ENST00000320936.5,ENST00000586636.1,ENST00000591055.1,ENST00000589235.1,ENST00000591659.1,ENST00000585914.1 |
| exon_skip_300493 | 19 | 1269354:1269409:1270926:1271035:1271327:1271360 | 1270926:1271035 | ENSG00000099622.9 | ENST00000587169.1,ENST00000444172.2,ENST00000593048.1,ENST00000592412.1,ENST00000591376.1 |
| exon_skip_300499 | 19 | 1270926:1271035:1271119:1271245:1271327:1271360 | 1271119:1271245 | ENSG00000099622.9 | ENST00000591097.1,ENST00000590171.1 |
| exon_skip_300500 | 19 | 1270926:1271035:1271138:1271245:1271327:1271360 | 1271138:1271245 | ENSG00000099622.9 | ENST00000588030.1,ENST00000588411.1,ENST00000589660.1,ENST00000589266.1,ENST00000588090.1,ENST00000591935.1,ENST00000586548.1,ENST00000585913.1,ENST00000589710.1,ENST00000588230.1,ENST00000413636.2,ENST00000586472.1,ENST00000589686.1,ENST00000587323.1,ENS |
| exon_skip_300501 | 19 | 1271138:1271245:1271327:1271364:1271549:1271631 | 1271327:1271364 | ENSG00000099622.9 | ENST00000413636.2 |
| exon_skip_300502 | 19 | 1271138:1271245:1271327:1271466:1271549:1271631 | 1271327:1271466 | ENSG00000099622.9 | ENST00000588030.1,ENST00000589660.1,ENST00000588090.1,ENST00000591935.1,ENST00000586548.1,ENST00000585913.1,ENST00000589710.1,ENST00000588230.1,ENST00000591097.1,ENST00000586472.1,ENST00000589686.1,ENST00000587323.1,ENST00000320936.5,ENST00000586636.1,ENS |
| exon_skip_300504 | 19 | 1271327:1271364:1271549:1271631:1271979:1272027 | 1271549:1271631 | ENSG00000099622.9 | ENST00000413636.2,ENST00000590347.1,ENST00000591055.1 |
| exon_skip_300514 | 19 | 1271449:1271466:1271549:1271631:1271979:1272027 | 1271549:1271631 | ENSG00000099622.9 | ENST00000588030.1,ENST00000589660.1,ENST00000588090.1,ENST00000591935.1,ENST00000586548.1,ENST00000585913.1,ENST00000593128.1,ENST00000589710.1,ENST00000588230.1,ENST00000590704.1,ENST00000586472.1,ENST00000589686.1,ENST00000593093.1,ENST00000587169.1,ENS |
| exon_skip_300534 | 19 | 1271979:1272050:1273492:1273714:1274305:1274362 | 1273492:1273714 | ENSG00000099622.9 | ENST00000585914.1 |
| exon_skip_300537 | 19 | 1271979:1272050:1273599:1273714:1274305:1274362 | 1273599:1273714 | ENSG00000099622.9 | ENST00000592234.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for CIRBP |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000320936 | 1270926 | 1271035 | 5CDS-5UTR |
| ENST00000586472 | 1270878 | 1270881 | 5UTR-5UTR |
| ENST00000320936 | 1271138 | 1271245 | Frame-shift |
| ENST00000585630 | 1271138 | 1271245 | Frame-shift |
| ENST00000586472 | 1271138 | 1271245 | Frame-shift |
| ENST00000588030 | 1271138 | 1271245 | Frame-shift |
| ENST00000588090 | 1271138 | 1271245 | Frame-shift |
| ENST00000320936 | 1271327 | 1271466 | Frame-shift |
| ENST00000585630 | 1271327 | 1271466 | Frame-shift |
| ENST00000586472 | 1271327 | 1271466 | Frame-shift |
| ENST00000588030 | 1271327 | 1271466 | Frame-shift |
| ENST00000588090 | 1271327 | 1271466 | Frame-shift |
| ENST00000320936 | 1271549 | 1271631 | Frame-shift |
| ENST00000585630 | 1271549 | 1271631 | Frame-shift |
| ENST00000586472 | 1271549 | 1271631 | Frame-shift |
| ENST00000588030 | 1271549 | 1271631 | Frame-shift |
| ENST00000588090 | 1271549 | 1271631 | Frame-shift |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000320936 | 1270926 | 1271035 | 5CDS-5UTR |
| ENST00000586472 | 1270878 | 1270881 | 5UTR-5UTR |
| ENST00000320936 | 1271138 | 1271245 | Frame-shift |
| ENST00000585630 | 1271138 | 1271245 | Frame-shift |
| ENST00000586472 | 1271138 | 1271245 | Frame-shift |
| ENST00000588030 | 1271138 | 1271245 | Frame-shift |
| ENST00000588090 | 1271138 | 1271245 | Frame-shift |
| ENST00000320936 | 1271327 | 1271466 | Frame-shift |
| ENST00000585630 | 1271327 | 1271466 | Frame-shift |
| ENST00000586472 | 1271327 | 1271466 | Frame-shift |
| ENST00000588030 | 1271327 | 1271466 | Frame-shift |
| ENST00000588090 | 1271327 | 1271466 | Frame-shift |
| ENST00000320936 | 1271549 | 1271631 | Frame-shift |
| ENST00000585630 | 1271549 | 1271631 | Frame-shift |
| ENST00000586472 | 1271549 | 1271631 | Frame-shift |
| ENST00000588030 | 1271549 | 1271631 | Frame-shift |
| ENST00000588090 | 1271549 | 1271631 | Frame-shift |
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Infer the effects of exon skipping event on protein functional features for CIRBP |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for CIRBP |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
CIRBP_CESC_exon_skip_300485_psi_boxplot.png |
CIRBP_PRAD_exon_skip_300499_psi_boxplot.png |
CIRBP_STAD_exon_skip_300502_psi_boxplot.png |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_300485 | 1270866 | 1271035 | 1270955 | 1270955 | Frame_Shift_Del | T | - | p.L8fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_300492 exon_skip_300493 | 1270927 | 1271035 | 1270955 | 1270955 | Frame_Shift_Del | T | - | p.L8fs |
| STAD | TCGA-HU-A4H8-01 | exon_skip_300502 | 1271328 | 1271466 | 1271433 | 1271433 | Frame_Shift_Del | G | - | p.G106fs |
| STAD | TCGA-HU-A4H8-01 | exon_skip_300502 | 1271328 | 1271466 | 1271433 | 1271433 | Frame_Shift_Del | G | - | p.R105fs |
| UCEC | TCGA-D1-A101-01 | exon_skip_300504 exon_skip_300514 | 1271550 | 1271631 | 1271570 | 1271570 | Frame_Shift_Del | G | - | p.G124fs |
| BLCA | TCGA-G2-A2ES-01 | exon_skip_300485 | 1270866 | 1271035 | 1270999 | 1270999 | Nonsense_Mutation | G | A | p.W5* |
| BLCA | TCGA-G2-A2ES-01 | exon_skip_300492 exon_skip_300493 | 1270927 | 1271035 | 1270999 | 1270999 | Nonsense_Mutation | G | A | p.W5* |
| CESC | TCGA-C5-A7UH-01 | exon_skip_300485 | 1270866 | 1271035 | 1271012 | 1271012 | Nonsense_Mutation | C | T | p.Q10* |
| CESC | TCGA-C5-A7UH-01 | exon_skip_300492 exon_skip_300493 | 1270927 | 1271035 | 1271012 | 1271012 | Nonsense_Mutation | C | T | p.Q10* |
| PRAD | TCGA-EJ-7782-01 | exon_skip_300500 exon_skip_300499 | 1271120 | 1271245 | 1271165 | 1271165 | Nonsense_Mutation | C | T | p.Q44* |
| PRAD | TCGA-EJ-7782-01 | exon_skip_300500 exon_skip_300499 | 1271120 | 1271245 | 1271165 | 1271165 | Nonsense_Mutation | C | T | p.Q44X |
| PRAD | TCGA-EJ-7782-01 | exon_skip_300500 exon_skip_300499 | 1271139 | 1271245 | 1271165 | 1271165 | Nonsense_Mutation | C | T | p.Q44* |
| PRAD | TCGA-EJ-7782-01 | exon_skip_300500 exon_skip_300499 | 1271139 | 1271245 | 1271165 | 1271165 | Nonsense_Mutation | C | T | p.Q44X |
| BLCA | TCGA-XF-AAN7-01 | exon_skip_300502 | 1271328 | 1271466 | 1271439 | 1271439 | Nonsense_Mutation | C | T | p.R55* |
| LUSC | TCGA-37-3789-01 | exon_skip_300504 exon_skip_300514 | 1271550 | 1271631 | 1271623 | 1271623 | Nonsense_Mutation | C | A | p.Y141* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
 | Sample: TCGA-37-3789-01 |
| Cancer type: LUSC | |
| ESID: exon_skip_300514 | |
| Skipped exon start: 1271550 | |
| Skipped exon end: 1271631 | |
| Mutation start: 1271623 | |
| Mutation end: 1271623 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: A | |
| AAchange: p.Y141* | |
exon_skip_300504_LUSC_TCGA-37-3789-01.png | |
 | Sample: TCGA-D1-A101-01 |
| Cancer type: UCEC | |
| ESID: exon_skip_300514 | |
| Skipped exon start: 1271550 | |
| Skipped exon end: 1271631 | |
| Mutation start: 1271570 | |
| Mutation end: 1271570 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: G | |
| Mutation seq: - | |
| AAchange: p.G124fs | |
exon_skip_27592_UCEC_TCGA-D1-A101-01.png | |
exon_skip_300504_UCEC_TCGA-D1-A101-01.png | |
exon_skip_347981_UCEC_TCGA-D1-A101-01.png | |
exon_skip_510597_UCEC_TCGA-D1-A101-01.png | |
 | Sample: TCGA-HU-A4H8-01 |
| Cancer type: STAD | |
| ESID: exon_skip_300502 | |
| Skipped exon start: 1271328 | |
| Skipped exon end: 1271466 | |
| Mutation start: 1271433 | |
| Mutation end: 1271433 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: G | |
| Mutation seq: - | |
| AAchange: p.R105fs | |
| Sample: TCGA-HU-A4H8-01 |
| Cancer type: STAD | |
| ESID: exon_skip_300502 | |
| Skipped exon start: 1271328 | |
| Skipped exon end: 1271466 | |
| Mutation start: 1271433 | |
| Mutation end: 1271433 | |
| Mutation type: Frame_Shift_Del | |
| Reference seq: G | |
| Mutation seq: - | |
| AAchange: p.G106fs | |
exon_skip_300502_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_343108_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_450280_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_452918_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_472769_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_472770_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_496317_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_66251_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_66260_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_66262_STAD_TCGA-HU-A4H8-01.png | |
exon_skip_98460_STAD_TCGA-HU-A4H8-01.png | |
 | Sample: TCGA-EJ-7782-01 |
| Cancer type: PRAD | |
| ESID: exon_skip_300499 | |
| Skipped exon start: 1271139 | |
| Skipped exon end: 1271245 | |
| Mutation start: 1271165 | |
| Mutation end: 1271165 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.Q44X | |
| Sample: TCGA-EJ-7782-01 |
| Cancer type: PRAD | |
| ESID: exon_skip_300499 | |
| Skipped exon start: 1271120 | |
| Skipped exon end: 1271245 | |
| Mutation start: 1271165 | |
| Mutation end: 1271165 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.Q44X | |
| Sample: TCGA-EJ-7782-01 |
| Cancer type: PRAD | |
| ESID: exon_skip_300499 | |
| Skipped exon start: 1271139 | |
| Skipped exon end: 1271245 | |
| Mutation start: 1271165 | |
| Mutation end: 1271165 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.Q44* | |
| Sample: TCGA-EJ-7782-01 |
| Cancer type: PRAD | |
| ESID: exon_skip_300499 | |
| Skipped exon start: 1271120 | |
| Skipped exon end: 1271245 | |
| Mutation start: 1271165 | |
| Mutation end: 1271165 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.Q44* | |
exon_skip_112584_PRAD_TCGA-EJ-7782-01.png | |
exon_skip_300499_PRAD_TCGA-EJ-7782-01.png | |
exon_skip_310302_PRAD_TCGA-EJ-7782-01.png | |
 | Sample: TCGA-C5-A7UH-01 |
| Cancer type: CESC | |
| ESID: exon_skip_300485 | |
| Skipped exon start: 1270866 | |
| Skipped exon end: 1271035 | |
| Mutation start: 1271012 | |
| Mutation end: 1271012 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.Q10* | |
| Sample: TCGA-C5-A7UH-01 |
| Cancer type: CESC | |
| ESID: exon_skip_300493 | |
| Skipped exon start: 1270927 | |
| Skipped exon end: 1271035 | |
| Mutation start: 1271012 | |
| Mutation end: 1271012 | |
| Mutation type: Nonsense_Mutation | |
| Reference seq: C | |
| Mutation seq: T | |
| AAchange: p.Q10* | |
exon_skip_300485_CESC_TCGA-C5-A7UH-01.png | |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| TGBC11TKB_STOMACH | 1271550 | 1271631 | 1271570 | 1271570 | Frame_Shift_Del | G | - | p.G125fs |
| SNGM_ENDOMETRIUM | 1270866 | 1271035 | 1271017 | 1271017 | Missense_Mutation | T | G | p.Y29D |
| SNGM_ENDOMETRIUM | 1270927 | 1271035 | 1271017 | 1271017 | Missense_Mutation | T | G | p.Y29D |
| JHUEM1_ENDOMETRIUM | 1271139 | 1271245 | 1271175 | 1271175 | Missense_Mutation | G | A | p.R47Q |
| JHUEM1_ENDOMETRIUM | 1271120 | 1271245 | 1271175 | 1271175 | Missense_Mutation | G | A | p.R47Q |
| MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1271139 | 1271245 | 1271232 | 1271232 | Missense_Mutation | C | A | p.A66D |
| MOLT4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1271120 | 1271245 | 1271232 | 1271232 | Missense_Mutation | C | A | p.A66D |
| JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1271328 | 1271466 | 1271371 | 1271371 | Missense_Mutation | C | T | p.S85L |
| HDQP1_BREAST | 1271328 | 1271466 | 1271380 | 1271380 | Missense_Mutation | A | G | p.N88S |
| LS180_LARGE_INTESTINE | 1271328 | 1271466 | 1271407 | 1271407 | Missense_Mutation | C | T | p.S97F |
| REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 1271328 | 1271466 | 1271430 | 1271430 | Missense_Mutation | C | G | p.R105G |
| CAL78_BONE | 1271550 | 1271631 | 1271585 | 1271585 | Missense_Mutation | G | A | p.E129K |
| UMUC16_URINARY_TRACT | 1270866 | 1271035 | 1270945 | 1270945 | Nonsense_Mutation | G | T | p.E5* |
| UMUC16_URINARY_TRACT | 1270927 | 1271035 | 1270945 | 1270945 | Nonsense_Mutation | G | T | p.E5* |
| SNU1040_LARGE_INTESTINE | 1271328 | 1271466 | 1271382 | 1271382 | Nonsense_Mutation | C | T | p.R89* |
| SNU1040_LARGE_INTESTINE | 1270866 | 1271035 | 1271034 | 1271035 | Splice_Site | - | GT | p.V35fs |
| SNU1040_LARGE_INTESTINE | 1270927 | 1271035 | 1271034 | 1271035 | Splice_Site | - | GT | p.V35fs |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for CIRBP |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CIRBP |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for CIRBP |
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RelatedDrugs for CIRBP |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CIRBP |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| CIRBP | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| CIRBP | C0600467 | Neurogenic Inflammation | 1 | CTD_human |
| CIRBP | C0751865 | Alcohol-Induced Disorders, Nervous System | 1 | CTD_human |
| CIRBP | C1510586 | Autism Spectrum Disorders | 1 | CTD_human |
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