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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for UBE4B |
 Gene summary |
| Gene information | Gene symbol | UBE4B | Gene ID | 10277 |
| Gene name | ubiquitination factor E4B | |
| Synonyms | E4|HDNB1|UBOX3|UFD2|UFD2A | |
| Cytomap | 1p36.22 | |
| Type of gene | protein-coding | |
| Description | ubiquitin conjugation factor E4 BRING-type E3 ubiquitin transferase E4 BUFD2A-III/UBE4B-III splice isoformhomologous to yeast UFD2homozygously deleted in neuroblastoma-1ubiquitin-fusion degradation protein 2ubiquitination factor E4B (UFD2 homolog, y | |
| Modification date | 20180523 | |
| UniProtAcc | O95155 | |
| Context | PubMed: UBE4B [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| UBE4B | GO:0008626 | granzyme-mediated apoptotic signaling pathway | 11802788 |
| UBE4B | GO:0009411 | response to UV | 11802788 |
| UBE4B | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 23509263 |
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Exon skipping events across known transcript of Ensembl for UBE4B from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for UBE4B |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for UBE4B |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_1059 | 1 | 10093653:10093752:10132085:10132272:10155518:10155654 | 10132085:10132272 | ENSG00000130939.14 | ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1060 | 1 | 10132085:10132272:10155518:10155654:10161165:10161253 | 10155518:10155654 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1063 | 1 | 10165573:10165802:10166254:10166641:10177516:10177658 | 10166254:10166641 | ENSG00000130939.14 | ENST00000343090.6 |
| exon_skip_1065 | 1 | 10177516:10177658:10179570:10179671:10182019:10182134 | 10179570:10179671 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000475795.1,ENST00000343090.6 |
| exon_skip_1068 | 1 | 10179570:10179671:10182019:10182134:10186851:10186935 | 10182019:10182134 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000475795.1,ENST00000343090.6 |
| exon_skip_1071 | 1 | 10189449:10189506:10190557:10190674:10190772:10190871 | 10190557:10190674 | ENSG00000130939.14 | ENST00000253251.8,ENST00000466379.1,ENST00000377157.3,ENST00000475795.1,ENST00000343090.6 |
| exon_skip_1072 | 1 | 10190772:10190871:10192426:10192540:10195045:10195244 | 10192426:10192540 | ENSG00000130939.14 | ENST00000470736.1,ENST00000253251.8,ENST00000466379.1,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1073 | 1 | 10195045:10195244:10197124:10197263:10204997:10205097 | 10197124:10197263 | ENSG00000130939.14 | ENST00000470736.1,ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1075 | 1 | 10197124:10197263:10204997:10205097:10207020:10207148 | 10204997:10205097 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1077 | 1 | 10209241:10209340:10211383:10211619:10218413:10218540 | 10211383:10211619 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1079 | 1 | 10221199:10221344:10226301:10226400:10228193:10228328 | 10226301:10226400 | ENSG00000130939.14 | ENST00000488228.1 |
| exon_skip_1082 | 1 | 10221199:10221344:10228193:10228328:10231195:10231247 | 10228193:10228328 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1087 | 1 | 10228193:10228328:10231195:10231387:10238701:10238876 | 10231195:10231387 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for UBE4B |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_1059 | 1 | 10093653:10093752:10132085:10132272:10155518:10155654 | 10132085:10132272 | ENSG00000130939.14 | ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1060 | 1 | 10132085:10132272:10155518:10155654:10161165:10161253 | 10155518:10155654 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1063 | 1 | 10165573:10165802:10166254:10166641:10177516:10177658 | 10166254:10166641 | ENSG00000130939.14 | ENST00000343090.6 |
| exon_skip_1065 | 1 | 10177516:10177658:10179570:10179671:10182019:10182134 | 10179570:10179671 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6,ENST00000475795.1 |
| exon_skip_1068 | 1 | 10179570:10179671:10182019:10182134:10186851:10186935 | 10182019:10182134 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6,ENST00000475795.1 |
| exon_skip_1071 | 1 | 10189449:10189506:10190557:10190674:10190772:10190871 | 10190557:10190674 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6,ENST00000475795.1,ENST00000466379.1 |
| exon_skip_1072 | 1 | 10190772:10190871:10192426:10192540:10195045:10195244 | 10192426:10192540 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6,ENST00000470736.1,ENST00000466379.1 |
| exon_skip_1073 | 1 | 10195045:10195244:10197124:10197263:10204997:10205097 | 10197124:10197263 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6,ENST00000470736.1 |
| exon_skip_1075 | 1 | 10197124:10197263:10204997:10205097:10207020:10207148 | 10204997:10205097 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1077 | 1 | 10209241:10209340:10211383:10211619:10218413:10218540 | 10211383:10211619 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1079 | 1 | 10221199:10221344:10226301:10226400:10228193:10228328 | 10226301:10226400 | ENSG00000130939.14 | ENST00000488228.1 |
| exon_skip_1082 | 1 | 10221199:10221344:10228193:10228328:10231195:10231247 | 10228193:10228328 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| exon_skip_1087 | 1 | 10228193:10228328:10231195:10231387:10238701:10238876 | 10231195:10231387 | ENSG00000130939.14 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for UBE4B |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000343090 | 10132085 | 10132272 | Frame-shift |
| ENST00000343090 | 10155518 | 10155654 | Frame-shift |
| ENST00000343090 | 10179570 | 10179671 | Frame-shift |
| ENST00000343090 | 10182019 | 10182134 | Frame-shift |
| ENST00000343090 | 10197124 | 10197263 | Frame-shift |
| ENST00000343090 | 10204997 | 10205097 | Frame-shift |
| ENST00000343090 | 10211383 | 10211619 | Frame-shift |
| ENST00000343090 | 10218413 | 10218540 | Frame-shift |
| ENST00000343090 | 10166254 | 10166641 | In-frame |
| ENST00000343090 | 10190557 | 10190674 | In-frame |
| ENST00000343090 | 10192426 | 10192540 | In-frame |
| ENST00000343090 | 10228193 | 10228328 | In-frame |
| ENST00000343090 | 10231195 | 10231387 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000343090 | 10132085 | 10132272 | Frame-shift |
| ENST00000343090 | 10155518 | 10155654 | Frame-shift |
| ENST00000343090 | 10179570 | 10179671 | Frame-shift |
| ENST00000343090 | 10182019 | 10182134 | Frame-shift |
| ENST00000343090 | 10197124 | 10197263 | Frame-shift |
| ENST00000343090 | 10204997 | 10205097 | Frame-shift |
| ENST00000343090 | 10211383 | 10211619 | Frame-shift |
| ENST00000343090 | 10218413 | 10218540 | Frame-shift |
| ENST00000343090 | 10166254 | 10166641 | In-frame |
| ENST00000343090 | 10190557 | 10190674 | In-frame |
| ENST00000343090 | 10192426 | 10192540 | In-frame |
| ENST00000343090 | 10228193 | 10228328 | In-frame |
| ENST00000343090 | 10231195 | 10231387 | In-frame |
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Infer the effects of exon skipping event on protein functional features for UBE4B |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000343090 | 5284 | 1302 | 10166254 | 10166641 | 885 | 1271 | 270 | 398 |
| ENST00000343090 | 5284 | 1302 | 10190557 | 10190674 | 1771 | 1887 | 565 | 604 |
| ENST00000343090 | 5284 | 1302 | 10192426 | 10192540 | 1987 | 2100 | 637 | 675 |
| ENST00000343090 | 5284 | 1302 | 10228193 | 10228328 | 3274 | 3408 | 1066 | 1111 |
| ENST00000343090 | 5284 | 1302 | 10231195 | 10231387 | 3409 | 3600 | 1111 | 1175 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000343090 | 5284 | 1302 | 10166254 | 10166641 | 885 | 1271 | 270 | 398 |
| ENST00000343090 | 5284 | 1302 | 10190557 | 10190674 | 1771 | 1887 | 565 | 604 |
| ENST00000343090 | 5284 | 1302 | 10192426 | 10192540 | 1987 | 2100 | 637 | 675 |
| ENST00000343090 | 5284 | 1302 | 10228193 | 10228328 | 3274 | 3408 | 1066 | 1111 |
| ENST00000343090 | 5284 | 1302 | 10231195 | 10231387 | 3409 | 3600 | 1111 | 1175 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
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SNVs in the skipped exons for UBE4B |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_1060 | 10155519 | 10155654 | 10155615 | 10155615 | Frame_Shift_Del | C | - | p.S103fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_1071 | 10190558 | 10190674 | 10190610 | 10190610 | Frame_Shift_Del | G | - | p.R338fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_1073 | 10197125 | 10197263 | 10197175 | 10197175 | Frame_Shift_Del | T | - | p.F514fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_1077 | 10211384 | 10211619 | 10211401 | 10211401 | Frame_Shift_Del | T | - | p.L658fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_1077 | 10211384 | 10211619 | 10211539 | 10211539 | Frame_Shift_Del | C | - | p.T704fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_1077 | 10211384 | 10211619 | 10211547 | 10211547 | Frame_Shift_Del | T | - | p.F708fs |
| LIHC | TCGA-DD-A3A0-01 | exon_skip_1077 | 10211384 | 10211619 | 10211547 | 10211547 | Frame_Shift_Del | T | - | p.F708fs |
| COAD | TCGA-A6-2676-01 | exon_skip_1077 | 10211384 | 10211619 | 10211546 | 10211547 | Frame_Shift_Ins | - | T | p.K822fs |
| COAD | TCGA-AA-3663-01 | exon_skip_1087 | 10231196 | 10231387 | 10231210 | 10231211 | Frame_Shift_Ins | - | T | p.R1116fs |
| BLCA | TCGA-UY-A9PF-01 | exon_skip_1059 | 10132086 | 10132272 | 10132131 | 10132131 | Nonsense_Mutation | C | T | p.Q24* |
| LUAD | TCGA-55-7994-01 | exon_skip_1060 | 10155519 | 10155654 | 10155609 | 10155609 | Nonsense_Mutation | C | G | p.S101* |
| CHOL | TCGA-W5-AA2U-01 | exon_skip_1075 | 10204998 | 10205097 | 10205034 | 10205034 | Nonsense_Mutation | G | A | p.W555* |
| CHOL | TCGA-W5-AA2U-01 | exon_skip_1075 | 10204998 | 10205097 | 10205034 | 10205034 | Nonsense_Mutation | G | A | p.W800X |
| SKCM | TCGA-FW-A3R5-06 | exon_skip_1082 | 10228194 | 10228328 | 10228227 | 10228227 | Nonsense_Mutation | C | T | p.Q833* |
| READ | TCGA-DC-6681-01 | exon_skip_1087 | 10231196 | 10231387 | 10231208 | 10231208 | Nonsense_Mutation | C | T | p.R1116X |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| SNU245_BILIARY_TRACT | 10190558 | 10190674 | 10190624 | 10190625 | Frame_Shift_Del | CT | - | p.L459fs |
| NCIH441_LUNG | 10190558 | 10190674 | 10190628 | 10190629 | Frame_Shift_Ins | - | TT | p.Y461fs |
| YT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10132086 | 10132272 | 10132125 | 10132125 | Missense_Mutation | A | T | p.T22S |
| NCIH1155_LUNG | 10132086 | 10132272 | 10132189 | 10132189 | Missense_Mutation | C | T | p.A43V |
| SNU1040_LARGE_INTESTINE | 10132086 | 10132272 | 10132189 | 10132189 | Missense_Mutation | C | T | p.A43V |
| HCC2998_LARGE_INTESTINE | 10132086 | 10132272 | 10132191 | 10132191 | Missense_Mutation | G | A | p.A44T |
| HCC1195_LUNG | 10132086 | 10132272 | 10132222 | 10132222 | Missense_Mutation | G | C | p.G54A |
| SNU719_STOMACH | 10155519 | 10155654 | 10155588 | 10155588 | Missense_Mutation | A | C | p.E94A |
| KYSE410_OESOPHAGUS | 10155519 | 10155654 | 10155605 | 10155605 | Missense_Mutation | C | T | p.L100F |
| KMBC2_URINARY_TRACT | 10155519 | 10155654 | 10155619 | 10155619 | Missense_Mutation | G | C | p.Q104H |
| HEC108_ENDOMETRIUM | 10155519 | 10155654 | 10155629 | 10155629 | Missense_Mutation | A | G | p.I108V |
| CORL32_LUNG | 10166255 | 10166641 | 10166292 | 10166292 | Missense_Mutation | T | A | p.W283R |
| CCRFCEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10166255 | 10166641 | 10166317 | 10166317 | Missense_Mutation | C | T | p.P291L |
| CAOV3_OVARY | 10166255 | 10166641 | 10166502 | 10166502 | Missense_Mutation | C | A | p.P353T |
| WIL2NS_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10166255 | 10166641 | 10166502 | 10166502 | Missense_Mutation | C | A | p.P353T |
| HEC59_ENDOMETRIUM | 10179571 | 10179671 | 10179582 | 10179582 | Missense_Mutation | G | C | p.Q321H |
| CAMA1_BREAST | 10182020 | 10182134 | 10182069 | 10182069 | Missense_Mutation | C | T | p.L368F |
| DOV13_OVARY | 10190558 | 10190674 | 10190589 | 10190589 | Missense_Mutation | C | A | p.S447Y |
| HS294T_SKIN | 10190558 | 10190674 | 10190589 | 10190589 | Missense_Mutation | C | A | p.S447Y |
| SNU407_LARGE_INTESTINE | 10190558 | 10190674 | 10190609 | 10190609 | Missense_Mutation | C | T | p.R454W |
| YH13_CENTRAL_NERVOUS_SYSTEM | 10192427 | 10192540 | 10192467 | 10192467 | Missense_Mutation | G | A | p.G522D |
| KMS34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10192427 | 10192540 | 10192472 | 10192472 | Missense_Mutation | A | C | p.T524P |
| CHLA32_BONE | 10192427 | 10192540 | 10192484 | 10192484 | Missense_Mutation | G | T | p.A528S |
| NCIH2342_LUNG | 10197125 | 10197263 | 10197130 | 10197130 | Missense_Mutation | G | T | p.D615Y |
| OVISE_OVARY | 10197125 | 10197263 | 10197199 | 10197199 | Missense_Mutation | C | T | p.L638F |
| ESS1_ENDOMETRIUM | 10197125 | 10197263 | 10197221 | 10197221 | Missense_Mutation | G | A | p.R645H |
| DV90_LUNG | 10197125 | 10197263 | 10197223 | 10197223 | Missense_Mutation | C | T | p.R646C |
| SNU1040_LARGE_INTESTINE | 10197125 | 10197263 | 10197224 | 10197224 | Missense_Mutation | G | A | p.R646H |
| HEC265_ENDOMETRIUM | 10197125 | 10197263 | 10197241 | 10197241 | Missense_Mutation | C | T | p.R652W |
| 2313287_STOMACH | 10197125 | 10197263 | 10197251 | 10197251 | Missense_Mutation | G | T | p.R655L |
| L540_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10204998 | 10205097 | 10205036 | 10205036 | Missense_Mutation | A | G | p.K672R |
| MM127_SKIN | 10211384 | 10211619 | 10211439 | 10211439 | Missense_Mutation | G | T | p.V787F |
| U178_CENTRAL_NERVOUS_SYSTEM | 10211384 | 10211619 | 10211505 | 10211505 | Missense_Mutation | A | T | p.M809L |
| SNU81_LARGE_INTESTINE | 10211384 | 10211619 | 10211543 | 10211543 | Missense_Mutation | G | T | p.Q821H |
| A673_BONE | 10218414 | 10218540 | 10218422 | 10218422 | Missense_Mutation | C | T | p.H850Y |
| CCK81_LARGE_INTESTINE | 10218414 | 10218540 | 10218482 | 10218482 | Missense_Mutation | A | G | p.I870V |
| SCLC22H_LUNG | 10228194 | 10228328 | 10228237 | 10228237 | Missense_Mutation | G | T | p.R952L |
| SCLC21H_LUNG | 10228194 | 10228328 | 10228237 | 10228237 | Missense_Mutation | G | T | p.R952L |
| FADU_UPPER_AERODIGESTIVE_TRACT | 10228194 | 10228328 | 10228246 | 10228246 | Missense_Mutation | G | A | p.R955H |
| P30OHK_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10228194 | 10228328 | 10228275 | 10228275 | Missense_Mutation | G | A | p.V965M |
| HUPT3_PANCREAS | 10231196 | 10231387 | 10231198 | 10231198 | Missense_Mutation | G | T | p.E983D |
| SNU626_CENTRAL_NERVOUS_SYSTEM | 10231196 | 10231387 | 10231365 | 10231365 | Missense_Mutation | C | T | p.A1039V |
| JURKAT_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 10132086 | 10132272 | 10132089 | 10132089 | Nonsense_Mutation | C | T | p.R10* |
| CAMA1_BREAST | 10182020 | 10182134 | 10182087 | 10182087 | Nonsense_Mutation | C | T | p.Q374* |
| IGROV1_OVARY | 10211384 | 10211619 | 10211541 | 10211541 | Nonsense_Mutation | C | T | p.Q821* |
| MKN1_STOMACH | 10228194 | 10228328 | 10228328 | 10228328 | Splice_Site | G | A | p.P982P |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for UBE4B |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | ACC | rs2273299 | chr1:10218439 | A/G | 3.69e-05 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | ACC | rs2273299 | chr1:10218439 | A/G | 3.69e-05 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | GBM | rs2273299 | chr1:10218439 | A/G | 7.46e-05 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | GBM | rs2273299 | chr1:10218439 | A/G | 7.58e-05 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | COAD | rs2273299 | chr1:10218439 | A/G | 2.20e-08 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | COAD | rs2273299 | chr1:10218439 | A/G | 2.20e-08 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | BLCA | rs2273299 | chr1:10218439 | A/G | 1.11e-06 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | BLCA | rs2273299 | chr1:10218439 | A/G | 1.11e-06 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | KIRP | rs2273299 | chr1:10218439 | A/G | 1.97e-07 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | KIRP | rs2273299 | chr1:10218439 | A/G | 1.97e-07 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | KIRC | rs2273299 | chr1:10218439 | A/G | 1.99e-19 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | KIRC | rs2273299 | chr1:10218439 | A/G | 1.99e-19 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | LIHC | rs2273299 | chr1:10218439 | A/G | 1.97e-05 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | LIHC | rs2273299 | chr1:10218439 | A/G | 1.98e-05 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | PCPG | rs2273299 | chr1:10218439 | A/G | 8.40e-08 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | PCPG | rs2273299 | chr1:10218439 | A/G | 8.66e-08 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | PAAD | rs2273299 | chr1:10218439 | A/G | 1.60e-07 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | PAAD | rs2273299 | chr1:10218439 | A/G | 1.60e-07 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | PRAD | rs2273299 | chr1:10218439 | A/G | 1.58e-12 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | PRAD | rs2273299 | chr1:10218439 | A/G | 1.58e-12 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | TGCT | rs2273299 | chr1:10218439 | A/G | 2.58e-04 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | TGCT | rs2273299 | chr1:10218439 | A/G | 2.58e-04 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | STAD | rs2273299 | chr1:10218439 | A/G | 3.61e-07 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | STAD | rs2273299 | chr1:10218439 | A/G | 3.62e-07 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | THCA | rs2273299 | chr1:10218439 | A/G | 4.19e-15 |
| exon_skip_1078 | 1 | 10211383:10211619:10218413:10218540:10221199:10221344 | 10218413:10218540 | ENST00000253251.8,ENST00000377157.3,ENST00000343090.6 | THCA | rs2273299 | chr1:10218439 | A/G | 4.20e-15 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for UBE4B |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for UBE4B |
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RelatedDrugs for UBE4B |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for UBE4B |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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