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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for MFSD10 |
 Gene summary |
| Gene information | Gene symbol | MFSD10 | Gene ID | 10227 |
| Gene name | major facilitator superfamily domain containing 10 | |
| Synonyms | TETRAN|TETTRAN | |
| Cytomap | 4p16.3 | |
| Type of gene | protein-coding | |
| Description | major facilitator superfamily domain-containing protein 10tetracycline transporter-like protein | |
| Modification date | 20180525 | |
| UniProtAcc | Q14728 | |
| Context | PubMed: MFSD10 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| MFSD10 | GO:0043252 | sodium-independent organic anion transport | 18638446 |
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Exon skipping events across known transcript of Ensembl for MFSD10 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for MFSD10 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for MFSD10 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_428125 | 4 | 2932337:2932680:2932787:2932877:2932953:2933001 | 2932787:2932877 | ENSG00000109736.10 | ENST00000507555.1,ENST00000507272.1,ENST00000329687.4,ENST00000514031.1,ENST00000355443.4,ENST00000503596.1 |
| exon_skip_428126 | 4 | 2932787:2932877:2932953:2933001:2933101:2933192 | 2932953:2933001 | ENSG00000109736.10 | ENST00000507555.1,ENST00000507272.1,ENST00000514800.1,ENST00000329687.4,ENST00000514031.1,ENST00000355443.4,ENST00000503596.1 |
| exon_skip_428129 | 4 | 2932953:2933001:2933101:2933192:2933551:2933663 | 2933101:2933192 | ENSG00000109736.10 | ENST00000507555.1,ENST00000512781.1 |
| exon_skip_428143 | 4 | 2933101:2933192:2933281:2933390:2933551:2933663 | 2933281:2933390 | ENSG00000109736.10 | ENST00000507272.1,ENST00000514800.1,ENST00000329687.4,ENST00000355443.4,ENST00000503596.1 |
| exon_skip_428151 | 4 | 2933101:2933192:2933551:2933663:2933771:2933880 | 2933551:2933663 | ENSG00000109736.10 | ENST00000507555.1 |
| exon_skip_428157 | 4 | 2933281:2933390:2933551:2933663:2933771:2933880 | 2933551:2933663 | ENSG00000109736.10 | ENST00000508221.1,ENST00000507272.1,ENST00000514800.1,ENST00000329687.4,ENST00000355443.4,ENST00000503596.1 |
| exon_skip_428168 | 4 | 2933791:2933880:2934077:2934136:2934326:2934417 | 2934077:2934136 | ENSG00000109736.10 | ENST00000503596.1 |
| exon_skip_428170 | 4 | 2933791:2933880:2934077:2934239:2934326:2934417 | 2934077:2934239 | ENSG00000109736.10 | ENST00000507555.1,ENST00000508221.1,ENST00000507272.1,ENST00000514800.1,ENST00000329687.4,ENST00000512781.1,ENST00000355443.4,ENST00000509676.1 |
| exon_skip_428196 | 4 | 2934077:2934136:2934326:2934485:2934832:2934904 | 2934326:2934485 | ENSG00000109736.10 | ENST00000503596.1 |
| exon_skip_428200 | 4 | 2934077:2934239:2934326:2934417:2934832:2934904 | 2934326:2934417 | ENSG00000109736.10 | ENST00000507272.1 |
| exon_skip_428203 | 4 | 2934077:2934239:2934326:2934485:2934832:2934904 | 2934326:2934485 | ENSG00000109736.10 | ENST00000507555.1,ENST00000508221.1,ENST00000514800.1,ENST00000329687.4,ENST00000355443.4 |
| exon_skip_428213 | 4 | 2934832:2934936:2935293:2935390:2935479:2935671 | 2935293:2935390 | ENSG00000109736.10 | ENST00000507555.1,ENST00000508221.1,ENST00000329687.4,ENST00000355443.4,ENST00000503596.1,ENST00000509676.1 |
| exon_skip_428220 | 4 | 2935293:2935390:2935479:2935671:2936495:2936523 | 2935479:2935671 | ENSG00000109736.10 | ENST00000507555.1,ENST00000508221.1,ENST00000355443.4,ENST00000503596.1,ENST00000509676.1 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for MFSD10 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_428125 | 4 | 2932337:2932680:2932787:2932877:2932953:2933001 | 2932787:2932877 | ENSG00000109736.10 | ENST00000514031.1,ENST00000355443.4,ENST00000329687.4,ENST00000503596.1,ENST00000507272.1,ENST00000507555.1 |
| exon_skip_428126 | 4 | 2932787:2932877:2932953:2933001:2933101:2933192 | 2932953:2933001 | ENSG00000109736.10 | ENST00000514800.1,ENST00000514031.1,ENST00000355443.4,ENST00000329687.4,ENST00000503596.1,ENST00000507272.1,ENST00000507555.1 |
| exon_skip_428129 | 4 | 2932953:2933001:2933101:2933192:2933551:2933663 | 2933101:2933192 | ENSG00000109736.10 | ENST00000507555.1,ENST00000512781.1 |
| exon_skip_428143 | 4 | 2933101:2933192:2933281:2933390:2933551:2933663 | 2933281:2933390 | ENSG00000109736.10 | ENST00000514800.1,ENST00000355443.4,ENST00000329687.4,ENST00000503596.1,ENST00000507272.1 |
| exon_skip_428151 | 4 | 2933101:2933192:2933551:2933663:2933771:2933880 | 2933551:2933663 | ENSG00000109736.10 | ENST00000507555.1 |
| exon_skip_428157 | 4 | 2933281:2933390:2933551:2933663:2933771:2933880 | 2933551:2933663 | ENSG00000109736.10 | ENST00000514800.1,ENST00000355443.4,ENST00000329687.4,ENST00000503596.1,ENST00000508221.1,ENST00000507272.1 |
| exon_skip_428168 | 4 | 2933791:2933880:2934077:2934136:2934326:2934417 | 2934077:2934136 | ENSG00000109736.10 | ENST00000503596.1 |
| exon_skip_428170 | 4 | 2933791:2933880:2934077:2934239:2934326:2934417 | 2934077:2934239 | ENSG00000109736.10 | ENST00000514800.1,ENST00000355443.4,ENST00000329687.4,ENST00000508221.1,ENST00000507272.1,ENST00000507555.1,ENST00000512781.1,ENST00000509676.1 |
| exon_skip_428196 | 4 | 2934077:2934136:2934326:2934485:2934832:2934904 | 2934326:2934485 | ENSG00000109736.10 | ENST00000503596.1 |
| exon_skip_428200 | 4 | 2934077:2934239:2934326:2934417:2934832:2934904 | 2934326:2934417 | ENSG00000109736.10 | ENST00000507272.1 |
| exon_skip_428203 | 4 | 2934077:2934239:2934326:2934485:2934832:2934904 | 2934326:2934485 | ENSG00000109736.10 | ENST00000514800.1,ENST00000355443.4,ENST00000329687.4,ENST00000508221.1,ENST00000507555.1 |
| exon_skip_428213 | 4 | 2934832:2934936:2935293:2935390:2935479:2935671 | 2935293:2935390 | ENSG00000109736.10 | ENST00000355443.4,ENST00000329687.4,ENST00000503596.1,ENST00000508221.1,ENST00000507555.1,ENST00000509676.1 |
| exon_skip_428220 | 4 | 2935293:2935390:2935479:2935671:2936495:2936523 | 2935479:2935671 | ENSG00000109736.10 | ENST00000355443.4,ENST00000503596.1,ENST00000508221.1,ENST00000507555.1,ENST00000509676.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for MFSD10 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000355443 | 2935479 | 2935671 | 3UTR-3CDS |
| ENST00000329687 | 2933281 | 2933390 | Frame-shift |
| ENST00000355443 | 2933281 | 2933390 | Frame-shift |
| ENST00000329687 | 2933551 | 2933663 | Frame-shift |
| ENST00000355443 | 2933551 | 2933663 | Frame-shift |
| ENST00000329687 | 2935293 | 2935390 | Frame-shift |
| ENST00000355443 | 2935293 | 2935390 | Frame-shift |
| ENST00000329687 | 2932787 | 2932877 | In-frame |
| ENST00000355443 | 2932787 | 2932877 | In-frame |
| ENST00000329687 | 2932953 | 2933001 | In-frame |
| ENST00000355443 | 2932953 | 2933001 | In-frame |
| ENST00000329687 | 2934077 | 2934239 | In-frame |
| ENST00000355443 | 2934077 | 2934239 | In-frame |
| ENST00000329687 | 2934326 | 2934485 | In-frame |
| ENST00000355443 | 2934326 | 2934485 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000355443 | 2935479 | 2935671 | 3UTR-3CDS |
| ENST00000329687 | 2933281 | 2933390 | Frame-shift |
| ENST00000355443 | 2933281 | 2933390 | Frame-shift |
| ENST00000329687 | 2933551 | 2933663 | Frame-shift |
| ENST00000355443 | 2933551 | 2933663 | Frame-shift |
| ENST00000329687 | 2935293 | 2935390 | Frame-shift |
| ENST00000355443 | 2935293 | 2935390 | Frame-shift |
| ENST00000329687 | 2932787 | 2932877 | In-frame |
| ENST00000355443 | 2932787 | 2932877 | In-frame |
| ENST00000329687 | 2932953 | 2933001 | In-frame |
| ENST00000355443 | 2932953 | 2933001 | In-frame |
| ENST00000329687 | 2934077 | 2934239 | In-frame |
| ENST00000355443 | 2934077 | 2934239 | In-frame |
| ENST00000329687 | 2934326 | 2934485 | In-frame |
| ENST00000355443 | 2934326 | 2934485 | In-frame |
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Infer the effects of exon skipping event on protein functional features for MFSD10 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000329687 | 2190 | 455 | 2934326 | 2934485 | 908 | 1066 | 124 | 177 |
| ENST00000355443 | 1770 | 455 | 2934326 | 2934485 | 485 | 643 | 124 | 177 |
| ENST00000329687 | 2190 | 455 | 2934077 | 2934239 | 1067 | 1228 | 177 | 231 |
| ENST00000355443 | 1770 | 455 | 2934077 | 2934239 | 644 | 805 | 177 | 231 |
| ENST00000329687 | 2190 | 455 | 2932953 | 2933001 | 1650 | 1697 | 371 | 387 |
| ENST00000355443 | 1770 | 455 | 2932953 | 2933001 | 1227 | 1274 | 371 | 387 |
| ENST00000329687 | 2190 | 455 | 2932787 | 2932877 | 1698 | 1787 | 387 | 417 |
| ENST00000355443 | 1770 | 455 | 2932787 | 2932877 | 1275 | 1364 | 387 | 417 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000329687 | 2190 | 455 | 2934326 | 2934485 | 908 | 1066 | 124 | 177 |
| ENST00000355443 | 1770 | 455 | 2934326 | 2934485 | 485 | 643 | 124 | 177 |
| ENST00000329687 | 2190 | 455 | 2934077 | 2934239 | 1067 | 1228 | 177 | 231 |
| ENST00000355443 | 1770 | 455 | 2934077 | 2934239 | 644 | 805 | 177 | 231 |
| ENST00000329687 | 2190 | 455 | 2932953 | 2933001 | 1650 | 1697 | 371 | 387 |
| ENST00000355443 | 1770 | 455 | 2932953 | 2933001 | 1227 | 1274 | 371 | 387 |
| ENST00000329687 | 2190 | 455 | 2932787 | 2932877 | 1698 | 1787 | 387 | 417 |
| ENST00000355443 | 1770 | 455 | 2932787 | 2932877 | 1275 | 1364 | 387 | 417 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q14728 | 124 | 177 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 124 | 177 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 124 | 177 | 113 | 135 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 113 | 135 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 148 | 168 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 148 | 168 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 177 | 231 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 177 | 231 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 202 | 222 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 202 | 222 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 371 | 387 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 371 | 387 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 371 | 387 | 359 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 371 | 387 | 359 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 387 | 417 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 387 | 417 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q14728 | 124 | 177 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 124 | 177 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 124 | 177 | 113 | 135 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 113 | 135 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 148 | 168 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 148 | 168 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 124 | 177 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 177 | 231 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 177 | 231 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 176 | 196 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 202 | 222 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 177 | 231 | 202 | 222 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 371 | 387 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 371 | 387 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 371 | 387 | 359 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 371 | 387 | 359 | 379 | Transmembrane | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q14728 | 387 | 417 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
| Q14728 | 387 | 417 | 1 | 455 | Chain | ID=PRO_0000324658;Note=Major facilitator superfamily domain-containing protein 10 |
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SNVs in the skipped exons for MFSD10 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| BLCA | TCGA-GV-A3QH-01 | exon_skip_428126 | 2932954 | 2933001 | 2932969 | 2932969 | Frame_Shift_Del | C | - | p.V383fs |
| BLCA | TCGA-GV-A3QH-01 | exon_skip_428126 | 2932954 | 2933001 | 2932969 | 2932969 | Frame_Shift_Del | C | - | p.V384fs |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_428129 | 2933102 | 2933192 | 2933121 | 2933121 | Frame_Shift_Del | C | - | p.G365fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_428168 | 2934078 | 2934136 | 2934081 | 2934081 | Frame_Shift_Del | T | - | p.K230fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_428170 | 2934078 | 2934239 | 2934081 | 2934081 | Frame_Shift_Del | T | - | p.K230fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_428170 | 2934078 | 2934239 | 2934227 | 2934227 | Frame_Shift_Del | C | - | p.V182fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_428200 | 2934327 | 2934417 | 2934406 | 2934406 | Frame_Shift_Del | C | - | p.G151fs |
| LIHC | TCGA-DD-A39Y-01 | exon_skip_428203 exon_skip_428196 | 2934327 | 2934485 | 2934406 | 2934406 | Frame_Shift_Del | C | - | p.G151fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_428200 | 2934327 | 2934417 | 2934406 | 2934406 | Frame_Shift_Del | C | - | p.G151fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_428203 exon_skip_428196 | 2934327 | 2934485 | 2934406 | 2934406 | Frame_Shift_Del | C | - | p.G151fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_428213 | 2935294 | 2935390 | 2935384 | 2935384 | Frame_Shift_Del | G | - | p.L60fs |
| STAD | TCGA-BR-8059-01 | exon_skip_428200 | 2934327 | 2934417 | 2934405 | 2934406 | Frame_Shift_Ins | - | C | p.G151fs |
| STAD | TCGA-BR-8059-01 | exon_skip_428203 exon_skip_428196 | 2934327 | 2934485 | 2934405 | 2934406 | Frame_Shift_Ins | - | C | p.G151fs |
| STAD | TCGA-BR-8059-01 | exon_skip_428200 | 2934327 | 2934417 | 2934406 | 2934407 | Frame_Shift_Ins | - | C | p.G151fs |
| STAD | TCGA-BR-8059-01 | exon_skip_428203 exon_skip_428196 | 2934327 | 2934485 | 2934406 | 2934407 | Frame_Shift_Ins | - | C | p.G151fs |
| KICH | TCGA-KL-8345-01 | exon_skip_428213 | 2935294 | 2935390 | 2935348 | 2935349 | Frame_Shift_Ins | - | A | p.F71fs |
| BLCA | TCGA-DK-A2I2-01 | exon_skip_428168 | 2934078 | 2934136 | 2934086 | 2934086 | Nonsense_Mutation | C | A | p.E229* |
| BLCA | TCGA-DK-A2I2-01 | exon_skip_428170 | 2934078 | 2934239 | 2934086 | 2934086 | Nonsense_Mutation | C | A | p.E229* |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| EN_ENDOMETRIUM | 2934078 | 2934239 | 2934167 | 2934167 | Frame_Shift_Del | T | - | p.M202fs |
| MHHPREB1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2935480 | 2935671 | 2935634 | 2935634 | Frame_Shift_Del | C | - | p.G8fs |
| HCC33_LUNG | 2932788 | 2932877 | 2932812 | 2932812 | Missense_Mutation | C | T | p.A410T |
| COLO668_LUNG | 2932788 | 2932877 | 2932857 | 2932857 | Missense_Mutation | T | C | p.T395A |
| MCC26_SKIN | 2933102 | 2933192 | 2933173 | 2933173 | Missense_Mutation | G | C | p.P348R |
| HEC265_ENDOMETRIUM | 2933282 | 2933390 | 2933298 | 2933298 | Missense_Mutation | A | G | p.V336A |
| GRST_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2933282 | 2933390 | 2933307 | 2933307 | Missense_Mutation | C | A | p.G333V |
| HEC1A_ENDOMETRIUM | 2933282 | 2933390 | 2933323 | 2933323 | Missense_Mutation | G | A | p.R328W |
| HEC1_ENDOMETRIUM | 2933282 | 2933390 | 2933323 | 2933323 | Missense_Mutation | G | A | p.R328W |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 2933552 | 2933663 | 2933568 | 2933568 | Missense_Mutation | G | A | p.R300C |
| GOS3_CENTRAL_NERVOUS_SYSTEM | 2933552 | 2933663 | 2933591 | 2933591 | Missense_Mutation | G | T | p.T292K |
| RERFLCMS_LUNG | 2933552 | 2933663 | 2933591 | 2933591 | Missense_Mutation | G | A | p.T292M |
| LS411N_LARGE_INTESTINE | 2933552 | 2933663 | 2933615 | 2933615 | Missense_Mutation | A | G | p.F284S |
| NCIH1693_LUNG | 2934078 | 2934239 | 2934091 | 2934091 | Missense_Mutation | G | A | p.P227L |
| NCIH1693_LUNG | 2934078 | 2934136 | 2934091 | 2934091 | Missense_Mutation | G | A | p.P227L |
| NCIH2110_LUNG | 2934078 | 2934239 | 2934098 | 2934098 | Missense_Mutation | T | C | p.T225A |
| NCIH2110_LUNG | 2934078 | 2934136 | 2934098 | 2934098 | Missense_Mutation | T | C | p.T225A |
| HEC59_ENDOMETRIUM | 2934078 | 2934239 | 2934192 | 2934192 | Missense_Mutation | C | T | p.M193I |
| CAL51_BREAST | 2934078 | 2934239 | 2934223 | 2934223 | Missense_Mutation | G | A | p.A183V |
| COLO668_LUNG | 2934327 | 2934417 | 2934352 | 2934352 | Missense_Mutation | G | A | p.S169L |
| COLO668_LUNG | 2934327 | 2934485 | 2934352 | 2934352 | Missense_Mutation | G | A | p.S169L |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 2934327 | 2934417 | 2934376 | 2934376 | Missense_Mutation | G | A | p.T161M |
| ISHIKAWAHERAKLIO02ER_ENDOMETRIUM | 2934327 | 2934485 | 2934376 | 2934376 | Missense_Mutation | G | A | p.T161M |
| SNU1040_LARGE_INTESTINE | 2934327 | 2934417 | 2934376 | 2934376 | Missense_Mutation | G | A | p.T161M |
| SNU1040_LARGE_INTESTINE | 2934327 | 2934485 | 2934376 | 2934376 | Missense_Mutation | G | A | p.T161M |
| RERFLCAD1_LUNG | 2934327 | 2934417 | 2934376 | 2934376 | Missense_Mutation | G | A | p.T161M |
| RERFLCAD1_LUNG | 2934327 | 2934485 | 2934376 | 2934376 | Missense_Mutation | G | A | p.T161M |
| LS411N_LARGE_INTESTINE | 2934327 | 2934417 | 2934389 | 2934389 | Missense_Mutation | C | T | p.V157I |
| LS411N_LARGE_INTESTINE | 2934327 | 2934485 | 2934389 | 2934389 | Missense_Mutation | C | T | p.V157I |
| MDAMB134VI_BREAST | 2934327 | 2934485 | 2934454 | 2934454 | Missense_Mutation | G | T | p.A135D |
| HEC6_ENDOMETRIUM | 2934327 | 2934485 | 2934467 | 2934467 | Missense_Mutation | A | G | p.Y131H |
| NCIH292_LUNG | 2935294 | 2935390 | 2935305 | 2935305 | Missense_Mutation | A | G | p.V86A |
| MCC26_SKIN | 2935294 | 2935390 | 2935346 | 2935347 | Missense_Mutation | GG | AA | p.A72V |
| IM9_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 2935294 | 2935390 | 2935357 | 2935357 | Missense_Mutation | C | G | p.D69H |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MFSD10 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MFSD10 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MFSD10 |
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RelatedDrugs for MFSD10 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MFSD10 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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