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| Open reading frame (ORF) annotation in the exon skipping event |
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| Splicing Quantitative Trait Loci (sQTLs) in the skipped exons |
| Splicing Quantitative Trait Methylation (sQTM) in the skipped exon |
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Gene summary for MPHOSPH9 |
 Gene summary |
| Gene information | Gene symbol | MPHOSPH9 | Gene ID | 10198 |
| Gene name | M-phase phosphoprotein 9 | |
| Synonyms | MPP-9|MPP9 | |
| Cytomap | 12q24.31 | |
| Type of gene | protein-coding | |
| Description | M-phase phosphoprotein 9 | |
| Modification date | 20180519 | |
| UniProtAcc | Q99550 | |
| Context | PubMed: MPHOSPH9 [Title/Abstract] AND exon [Title/Abstract] AND skip [Title/Abstract] - Title (PMID) |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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Exon skipping events across known transcript of Ensembl for MPHOSPH9 from UCSC genome browser |
| Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure. * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Gene isoform structures and expression levels for MPHOSPH9 |
| Expression levels of gene isoforms across TCGA. |
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| Expression levels of gene isoforms across GTEx. |
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Exon skipping events with PSIs in TCGA for MPHOSPH9 |
| Information of exkip skipping event in TCGA. |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_98178 | 12 | 123645814:123645930:123646661:123646739:123647560:123647583 | 123646661:123646739 | ENSG00000051825.10 | ENST00000606704.1 |
| exon_skip_98180 | 12 | 123645814:123645930:123646661:123646765:123647560:123647583 | 123646661:123646765 | ENSG00000051825.10 | ENST00000392425.3,ENST00000536198.1,ENST00000541076.2,ENST00000545556.2,ENST00000606320.1,ENST00000541603.2,ENST00000302349.5 |
| exon_skip_98182 | 12 | 123645814:123645930:123647560:123647681:123648496:123648508 | 123647560:123647681 | ENSG00000051825.10 | ENST00000539024.1,ENST00000302373.4 |
| exon_skip_98184 | 12 | 123646661:123646765:123647560:123647681:123648496:123648508 | 123647560:123647681 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000545556.2,ENST00000606320.1,ENST00000541603.2,ENST00000302349.5 |
| exon_skip_98185 | 12 | 123647630:123647681:123648496:123648637:123649848:123650009 | 123648496:123648637 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539024.1,ENST00000302373.4,ENST00000545556.2,ENST00000606320.1,ENST00000607619.1,ENST00000302349.5,ENST00000538250.1 |
| exon_skip_98186 | 12 | 123648496:123648637:123649848:123650024:123651201:123651336 | 123649848:123650024 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539024.1,ENST00000302373.4,ENST00000545556.2,ENST00000606320.1,ENST00000606321.1,ENST00000302349.5 |
| exon_skip_98188 | 12 | 123651201:123651336:123661234:123661336:123664472:123664527 | 123661234:123661336 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539024.1,ENST00000302373.4,ENST00000545556.2,ENST00000606320.1,ENST00000541823.1,ENST00000302349.5 |
| exon_skip_98189 | 12 | 123679055:123679148:123682793:123682881:123686710:123686866 | 123682793:123682881 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000606326.1,ENST00000539024.1,ENST00000302373.4,ENST00000545556.2,ENST00000606320.1,ENST00000302349.5 |
| exon_skip_98190 | 12 | 123682793:123682881:123686710:123686866:123687170:123687631 | 123686710:123686866 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539024.1,ENST00000302373.4,ENST00000606320.1,ENST00000302349.5 |
| exon_skip_98191 | 12 | 123687431:123687631:123687796:123687922:123694602:123694709 | 123687796:123687922 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539336.2,ENST00000606320.1,ENST00000302349.5 |
| exon_skip_98192 | 12 | 123687796:123687922:123694602:123694709:123699290:123699381 | 123694602:123694709 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539336.2,ENST00000545556.2,ENST00000606320.1,ENST00000302349.5 |
| exon_skip_98193 | 12 | 123694602:123694709:123699290:123699381:123702922:123703025 | 123699290:123699381 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000539024.1,ENST00000302373.4,ENST00000539336.2,ENST00000606320.1,ENST00000302349.5 |
| exon_skip_98194 | 12 | 123694602:123694709:123699290:123699381:123702945:123703046 | 123699290:123699381 | ENSG00000051825.10 | ENST00000545556.2 |
| exon_skip_98198 | 12 | 123699290:123699381:123702922:123703046:123705918:123706270 | 123702922:123703046 | ENSG00000051825.10 | ENST00000392425.3,ENST00000541076.2,ENST00000302373.4,ENST00000539336.2,ENST00000606320.1,ENST00000302349.5 |
| exon_skip_98200 | 12 | 123699290:123699381:123702945:123703046:123705918:123706270 | 123702945:123703046 | ENSG00000051825.10 | ENST00000545556.2 |
| exon_skip_98203 | 12 | 123706239:123706270:123707584:123707674:123712009:123712119 | 123707584:123707674 | ENSG00000051825.10 | ENST00000541437.1 |
| exon_skip_98206 | 12 | 123706389:123706442:123707584:123707674:123712009:123712119 | 123707584:123707674 | ENSG00000051825.10 | ENST00000535049.1,ENST00000606320.1 |
| exon_skip_98207 | 12 | 123706389:123706442:123707584:123707674:123714807:123714993 | 123707584:123707674 | ENSG00000051825.10 | ENST00000539639.1 |
| exon_skip_98210 | 12 | 123706389:123706442:123712009:123712163:123714807:123714993 | 123712009:123712163 | ENSG00000051825.10 | ENST00000541076.2 |
| exon_skip_98217 | 12 | 123707584:123707674:123710834:123710898:123712009:123712119 | 123710834:123710898 | ENSG00000051825.10 | ENST00000545556.2 |
| exon_skip_98220 | 12 | 123707584:123707674:123712009:123712119:123714807:123714961 | 123712009:123712119 | ENSG00000051825.10 | ENST00000535049.1 |
| exon_skip_98222 | 12 | 123707584:123707674:123712009:123712163:123714807:123714961 | 123712009:123712163 | ENSG00000051825.10 | ENST00000606320.1,ENST00000541437.1 |
| exon_skip_98223 | 12 | 123707584:123707674:123712092:123712163:123714807:123714961 | 123712092:123712163 | ENSG00000051825.10 | ENST00000538169.1 |
| exon_skip_98226 | 12 | 123710834:123710898:123712009:123712163:123714807:123714993 | 123712009:123712163 | ENSG00000051825.10 | ENST00000545556.2 |
| PSI values of skipped exons in TCGA. |
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Exon skipping events with PSIs in GTEx for MPHOSPH9 |
| Information of exkip skipping event in GTEx |
| Exon skip ID | chr | Exons involved in exon skipping | Skipped exon | ENSG | ENSTs |
| exon_skip_98178 | 12 | 123645814:123645930:123646661:123646739:123647560:123647583 | 123646661:123646739 | ENSG00000051825.10 | ENST00000606704.1 |
| exon_skip_98180 | 12 | 123645814:123645930:123646661:123646765:123647560:123647583 | 123646661:123646765 | ENSG00000051825.10 | ENST00000541603.2,ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000545556.2,ENST00000536198.1 |
| exon_skip_98182 | 12 | 123645814:123645930:123647560:123647681:123648496:123648508 | 123647560:123647681 | ENSG00000051825.10 | ENST00000302373.4,ENST00000539024.1 |
| exon_skip_98184 | 12 | 123646661:123646765:123647560:123647681:123648496:123648508 | 123647560:123647681 | ENSG00000051825.10 | ENST00000541603.2,ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000545556.2 |
| exon_skip_98185 | 12 | 123647630:123647681:123648496:123648637:123649848:123650009 | 123648496:123648637 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000545556.2,ENST00000539024.1,ENST00000538250.1,ENST00000607619.1 |
| exon_skip_98186 | 12 | 123648496:123648637:123649848:123650024:123651201:123651336 | 123649848:123650024 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000545556.2,ENST00000539024.1,ENST00000606321.1 |
| exon_skip_98188 | 12 | 123651201:123651336:123661234:123661336:123664472:123664527 | 123661234:123661336 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000545556.2,ENST00000539024.1,ENST00000541823.1 |
| exon_skip_98189 | 12 | 123679055:123679148:123682793:123682881:123686710:123686866 | 123682793:123682881 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000545556.2,ENST00000539024.1,ENST00000606326.1 |
| exon_skip_98190 | 12 | 123682793:123682881:123686710:123686866:123687170:123687631 | 123686710:123686866 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000539024.1 |
| exon_skip_98191 | 12 | 123687431:123687631:123687796:123687922:123694602:123694709 | 123687796:123687922 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000539336.2 |
| exon_skip_98192 | 12 | 123687796:123687922:123694602:123694709:123699290:123699381 | 123694602:123694709 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000545556.2,ENST00000539336.2 |
| exon_skip_98193 | 12 | 123694602:123694709:123699290:123699381:123702922:123703025 | 123699290:123699381 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000539024.1,ENST00000539336.2 |
| exon_skip_98194 | 12 | 123694602:123694709:123699290:123699381:123702945:123703046 | 123699290:123699381 | ENSG00000051825.10 | ENST00000545556.2 |
| exon_skip_98198 | 12 | 123699290:123699381:123702922:123703046:123705918:123706270 | 123702922:123703046 | ENSG00000051825.10 | ENST00000302349.5,ENST00000541076.2,ENST00000606320.1,ENST00000392425.3,ENST00000302373.4,ENST00000539336.2 |
| exon_skip_98200 | 12 | 123699290:123699381:123702945:123703046:123705918:123706270 | 123702945:123703046 | ENSG00000051825.10 | ENST00000545556.2 |
| exon_skip_98203 | 12 | 123706239:123706270:123707584:123707674:123712009:123712119 | 123707584:123707674 | ENSG00000051825.10 | ENST00000541437.1 |
| exon_skip_98206 | 12 | 123706389:123706442:123707584:123707674:123712009:123712119 | 123707584:123707674 | ENSG00000051825.10 | ENST00000606320.1,ENST00000535049.1 |
| exon_skip_98207 | 12 | 123706389:123706442:123707584:123707674:123714807:123714993 | 123707584:123707674 | ENSG00000051825.10 | ENST00000539639.1 |
| exon_skip_98210 | 12 | 123706389:123706442:123712009:123712163:123714807:123714993 | 123712009:123712163 | ENSG00000051825.10 | ENST00000541076.2 |
| exon_skip_98217 | 12 | 123707584:123707674:123710834:123710898:123712009:123712119 | 123710834:123710898 | ENSG00000051825.10 | ENST00000545556.2 |
| exon_skip_98220 | 12 | 123707584:123707674:123712009:123712119:123714807:123714961 | 123712009:123712119 | ENSG00000051825.10 | ENST00000535049.1 |
| exon_skip_98222 | 12 | 123707584:123707674:123712009:123712163:123714807:123714961 | 123712009:123712163 | ENSG00000051825.10 | ENST00000606320.1,ENST00000541437.1 |
| exon_skip_98223 | 12 | 123707584:123707674:123712092:123712163:123714807:123714961 | 123712092:123712163 | ENSG00000051825.10 | ENST00000538169.1 |
| PSI values of skipped exons in GTEx. |
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| * Skipped exon sequences. |
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Open reading frame (ORF) annotation in the exon skipping event for MPHOSPH9 |
| Open reading frame (ORF) of individual exon skipping events in TCGA based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000606320 | 123646661 | 123646765 | Frame-shift |
| ENST00000606320 | 123647560 | 123647681 | Frame-shift |
| ENST00000606320 | 123649848 | 123650024 | Frame-shift |
| ENST00000606320 | 123682793 | 123682881 | Frame-shift |
| ENST00000606320 | 123694602 | 123694709 | Frame-shift |
| ENST00000606320 | 123699290 | 123699381 | Frame-shift |
| ENST00000606320 | 123702922 | 123703046 | Frame-shift |
| ENST00000606320 | 123712009 | 123712163 | Frame-shift |
| ENST00000606320 | 123648496 | 123648637 | In-frame |
| ENST00000606320 | 123661234 | 123661336 | In-frame |
| ENST00000606320 | 123686710 | 123686866 | In-frame |
| ENST00000606320 | 123687796 | 123687922 | In-frame |
| ENST00000606320 | 123707584 | 123707674 | In-frame |
| Open reading frame (ORF) of individual exon skipping events in GTEx based on the Ensembl gene structure combined from isoforms. |
| ENST | Start of skipped exon | End of skipped exon | ORF |
| ENST00000606320 | 123646661 | 123646765 | Frame-shift |
| ENST00000606320 | 123647560 | 123647681 | Frame-shift |
| ENST00000606320 | 123649848 | 123650024 | Frame-shift |
| ENST00000606320 | 123682793 | 123682881 | Frame-shift |
| ENST00000606320 | 123694602 | 123694709 | Frame-shift |
| ENST00000606320 | 123699290 | 123699381 | Frame-shift |
| ENST00000606320 | 123702922 | 123703046 | Frame-shift |
| ENST00000606320 | 123712009 | 123712163 | Frame-shift |
| ENST00000606320 | 123648496 | 123648637 | In-frame |
| ENST00000606320 | 123661234 | 123661336 | In-frame |
| ENST00000606320 | 123686710 | 123686866 | In-frame |
| ENST00000606320 | 123687796 | 123687922 | In-frame |
| ENST00000606320 | 123707584 | 123707674 | In-frame |
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Infer the effects of exon skipping event on protein functional features for MPHOSPH9 |
| Exon skipping at the protein sequence level and followed lost functional features. * Click on the image to enlarge it in a new window. |
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| Loci of skipped exons in TCGA across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000606320 | 6368 | 1183 | 123707584 | 123707674 | 466 | 555 | 86 | 116 |
| ENST00000606320 | 6368 | 1183 | 123687796 | 123687922 | 1402 | 1527 | 398 | 440 |
| ENST00000606320 | 6368 | 1183 | 123686710 | 123686866 | 1989 | 2144 | 594 | 645 |
| ENST00000606320 | 6368 | 1183 | 123661234 | 123661336 | 2562 | 2663 | 785 | 818 |
| ENST00000606320 | 6368 | 1183 | 123648496 | 123648637 | 2975 | 3115 | 922 | 969 |
| Loci of skipped exons in GTEx across genomic, transcript, and protein sequence levels of In-frame cases. |
| ENST | Length of mRNA | Length of AA seq. | Genomic start | Genomic end | mRNA start | mRNA end | AA start | AA end |
| ENST00000606320 | 6368 | 1183 | 123707584 | 123707674 | 466 | 555 | 86 | 116 |
| ENST00000606320 | 6368 | 1183 | 123687796 | 123687922 | 1402 | 1527 | 398 | 440 |
| ENST00000606320 | 6368 | 1183 | 123686710 | 123686866 | 1989 | 2144 | 594 | 645 |
| ENST00000606320 | 6368 | 1183 | 123661234 | 123661336 | 2562 | 2663 | 785 | 818 |
| ENST00000606320 | 6368 | 1183 | 123648496 | 123648637 | 2975 | 3115 | 922 | 969 |
| Lost protein functional features of individual exon skipping events in TCGA. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q99550 | 86 | 116 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 398 | 440 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 594 | 645 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 594 | 645 | 609 | 804 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q99550 | 785 | 818 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 785 | 818 | 609 | 804 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q99550 | 922 | 969 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 922 | 969 | 947 | 947 | Sequence conflict | Note=K->E;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
| Lost protein functional features of individual exon skipping events in GTEx. |
| UniProt acc. | Start of exon skipping (AA) | End of exon skipping (AA) | Protein feature start (AA) | Protein feature end (AA) | Category of protein feature | Description of feature |
| Q99550 | 86 | 116 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 398 | 440 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 594 | 645 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 594 | 645 | 609 | 804 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q99550 | 785 | 818 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 785 | 818 | 609 | 804 | Coiled coil | Ontology_term=ECO:0000255;evidence=ECO:0000255 |
| Q99550 | 922 | 969 | 1 | 1183 | Chain | ID=PRO_0000096557;Note=M-phase phosphoprotein 9 |
| Q99550 | 922 | 969 | 947 | 947 | Sequence conflict | Note=K->E;Ontology_term=ECO:0000305;evidence=ECO:0000305 |
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SNVs in the skipped exons for MPHOSPH9 |
| - Lollipop plot for presenting exon skipping associated SNVs. * Click on the image to enlarge it in a new window. |
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| - Differential PSIs between mutated versus non-mutated samples. |
| - Non-synonymous mutations located in the skipped exons in TCGA. |
| Cancer type | Sample | ESID | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| LIHC | TCGA-DD-A1EG-01 | exon_skip_98185 | 123648497 | 123648637 | 123648586 | 123648586 | Frame_Shift_Del | T | - | p.K940fs |
| BLCA | TCGA-GU-AATP-01 | exon_skip_98186 | 123649849 | 123650024 | 123649869 | 123649872 | Frame_Shift_Del | TCTG | - | p.TE915fs |
| STAD | TCGA-B7-A5TI-01 | exon_skip_98186 | 123649849 | 123650024 | 123649959 | 123649959 | Frame_Shift_Del | T | - | p.K886fs |
| LIHC | TCGA-G3-A3CJ-01 | exon_skip_98191 | 123687797 | 123687922 | 123687813 | 123687813 | Frame_Shift_Del | G | - | p.P435fs |
| READ | TCGA-AG-A011-01 | exon_skip_98186 | 123649849 | 123650024 | 123649915 | 123649915 | Nonsense_Mutation | C | A | p.E749X |
| STAD | TCGA-BR-8680-01 | exon_skip_98186 | 123649849 | 123650024 | 123649915 | 123649915 | Nonsense_Mutation | C | A | p.E749* |
| STAD | TCGA-BR-8680-01 | exon_skip_98186 | 123649849 | 123650024 | 123649915 | 123649915 | Nonsense_Mutation | C | A | p.E749X |
| UCEC | TCGA-D1-A17Q-01 | exon_skip_98186 | 123649849 | 123650024 | 123649915 | 123649915 | Nonsense_Mutation | C | A | p.E749* |
| BRCA | TCGA-BH-A0HP-01 | exon_skip_98191 | 123687797 | 123687922 | 123687907 | 123687907 | Nonsense_Mutation | C | A | p.E252* |
| LUAD | TCGA-17-Z031-01 | exon_skip_98192 | 123694603 | 123694709 | 123694650 | 123694650 | Nonsense_Mutation | C | A | p.E383* |
| SKCM | TCGA-D3-A3MV-06 | exon_skip_98180 | 123646662 | 123646765 | 123646767 | 123646767 | Splice_Site | T | A | . |
| COAD | TCGA-AD-6889-01 | exon_skip_98192 | 123694603 | 123694709 | 123694601 | 123694601 | Splice_Site | A | G | . |
| UCS | TCGA-N8-A4PQ-01 | exon_skip_98200 exon_skip_98198 | 123702923 | 123703046 | 123703047 | 123703047 | Splice_Site | C | A | . |
| UCS | TCGA-N8-A4PQ-01 | exon_skip_98200 exon_skip_98198 | 123702946 | 123703046 | 123703047 | 123703047 | Splice_Site | C | A | . |
| - Depth of coverage in the three exons composing exon skipping event |
| Depth of coverage in three exons | Mutation description |
| - Non-synonymous mutations located in the skipped exons in CCLE. |
| Sample | Skipped exon start | Skipped exon end | Mutation start | Mutation end | Mutation type | Reference seq | Mutation seq | AAchange |
| 2313287_STOMACH | 123687797 | 123687922 | 123687866 | 123687866 | Frame_Shift_Del | T | - | p.K417fs |
| OVK18_OVARY | 123646662 | 123646765 | 123646704 | 123646704 | Missense_Mutation | G | T | p.P1031T |
| OVK18_OVARY | 123646662 | 123646739 | 123646704 | 123646704 | Missense_Mutation | G | T | p.P1031T |
| JHUEM7_ENDOMETRIUM | 123646662 | 123646765 | 123646743 | 123646743 | Missense_Mutation | A | C | p.L1018V |
| JHUEM7_ENDOMETRIUM | 123646662 | 123646739 | 123646743 | 123646743 | Missense_Mutation | A | C | p.L1018V |
| NCIBL128_MATCHED_NORMAL_TISSUE | 123647561 | 123647681 | 123647622 | 123647622 | Missense_Mutation | T | C | p.K990E |
| HEC1_ENDOMETRIUM | 123647561 | 123647681 | 123647633 | 123647633 | Missense_Mutation | T | C | p.K986R |
| LNCAPCLONEFGC_PROSTATE | 123649849 | 123650024 | 123649935 | 123649935 | Missense_Mutation | G | A | p.P894L |
| HCC2998_LARGE_INTESTINE | 123661235 | 123661336 | 123661250 | 123661250 | Missense_Mutation | C | T | p.R814K |
| SNUC5_LARGE_INTESTINE | 123661235 | 123661336 | 123661271 | 123661271 | Missense_Mutation | T | C | p.H807R |
| SW837_LARGE_INTESTINE | 123682794 | 123682881 | 123682856 | 123682856 | Missense_Mutation | G | A | p.H655Y |
| TCYIK_CERVIX | 123686711 | 123686866 | 123686807 | 123686807 | Missense_Mutation | T | C | p.Y614C |
| UBLC1_URINARY_TRACT | 123687797 | 123687922 | 123687841 | 123687841 | Missense_Mutation | C | G | p.E426Q |
| DOV13_OVARY | 123694603 | 123694709 | 123694620 | 123694620 | Missense_Mutation | C | G | p.D393H |
| HS294T_SKIN | 123694603 | 123694709 | 123694620 | 123694620 | Missense_Mutation | C | G | p.D393H |
| JHUEM7_ENDOMETRIUM | 123694603 | 123694709 | 123694657 | 123694657 | Missense_Mutation | T | G | p.E380D |
| SF172_CENTRAL_NERVOUS_SYSTEM | 123694603 | 123694709 | 123694662 | 123694662 | Missense_Mutation | G | A | p.P379S |
| SNU1033_LARGE_INTESTINE | 123694603 | 123694709 | 123694700 | 123694700 | Missense_Mutation | T | G | p.Y366S |
| KPNRTBM1_AUTONOMIC_GANGLIA | 123707585 | 123707674 | 123707614 | 123707614 | Missense_Mutation | G | T | p.Q107K |
| SNU1040_LARGE_INTESTINE | 123707585 | 123707674 | 123707663 | 123707663 | Missense_Mutation | T | A | p.L90F |
| OE33_OESOPHAGUS | 123712010 | 123712163 | 123712096 | 123712096 | Missense_Mutation | G | C | p.Q58E |
| OE33_OESOPHAGUS | 123712010 | 123712119 | 123712096 | 123712096 | Missense_Mutation | G | C | p.Q58E |
| OE33_OESOPHAGUS | 123712093 | 123712163 | 123712096 | 123712096 | Missense_Mutation | G | C | p.Q58E |
| MUTZ5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 123712010 | 123712163 | 123712131 | 123712131 | Missense_Mutation | G | T | p.S46Y |
| MUTZ5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | 123712093 | 123712163 | 123712131 | 123712131 | Missense_Mutation | G | T | p.S46Y |
| CW2_LARGE_INTESTINE | 123649849 | 123650024 | 123649884 | 123649884 | Nonsense_Mutation | C | T | p.W911* |
| KYSE140_OESOPHAGUS | 123686711 | 123686866 | 123686817 | 123686817 | Nonsense_Mutation | G | A | p.R611* |
| CAL12T_LUNG | 123646662 | 123646765 | 123646663 | 123646663 | Splice_Site | T | A | p.E1044D |
| CAL12T_LUNG | 123646662 | 123646739 | 123646663 | 123646663 | Splice_Site | T | A | p.E1044D |
| HT115_LARGE_INTESTINE | 123647561 | 123647681 | 123647562 | 123647562 | Splice_Site | G | A | p.R1010* |
| HCC2998_LARGE_INTESTINE | 123647561 | 123647681 | 123647562 | 123647562 | Splice_Site | G | A | p.R1010* |
| SNU324_PANCREAS | 123686711 | 123686866 | 123686711 | 123686711 | Splice_Site | C | A | p.R646I |
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Splicing Quantitative Trait Loci (sQTL) in the exon skipping event for MPHOSPH9 |
| sQTL information located at the skipped exons. |
| Exon skip ID | Chromosome | Three exons | Skippped exon | ENST | Cancer type | SNP id | Location | DNA change (ref/var) | P-value |
| exon_skip_98217 | 12 | 123707584:123707674:123710834:123710898:123712009:123712119 | 123710834:123710898 | ENST00000545556.2 | HNSC | rs1626703 | chr12:123710835 | A/C | 2.64e-03 |
| exon_skip_98217 | 12 | 123707584:123707674:123710834:123710898:123712009:123712119 | 123710834:123710898 | ENST00000545556.2 | HNSC | rs1626703 | chr12:123710835 | A/C | 2.64e-03 |
| exon_skip_98217 | 12 | 123707584:123707674:123710834:123710898:123712009:123712119 | 123710834:123710898 | ENST00000545556.2 | LAML | rs1626703 | chr12:123710835 | A/C | 1.56e-11 |
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Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MPHOSPH9 |
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Survival analysis of Splicing Quantitative Trait Methylation (sQTM) in the skipped exon for MPHOSPH9 |
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RelatedDrugs for MPHOSPH9 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MPHOSPH9 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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