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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for SNPH |
 Gene summary |
| Gene information | Gene symbol | SNPH | Gene ID | 9751 |
| Gene name | syntaphilin | |
| Synonyms | - | |
| Cytomap | 20p13 | |
| Type of gene | protein-coding | |
| Description | syntaphilin | |
| Modification date | 20200315 | |
| UniProtAcc | O15079, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for SNPH |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_912631(1271381, +), ADediting_912632(1271403, +), ADediting_912633(1271416, +), ADediting_912634(1271441, +), ADediting_912635(1271442, +), ADediting_912636(1271443, +), ADediting_912637(1271471, +), ADediting_912638(1271525, +), ADediting_912639(1271539, +), ADediting_912640(1271542, +), ADediting_912641(1271547, +), ADediting_912642(1271551, +), ADediting_912643(1276051, +), ADediting_912644(1278818, +), ADediting_912645(1278823, +), ADediting_912646(1279689, +), ADediting_912647(1279697, +), ADediting_912648(1279702, +), ADediting_912649(1285919, +), ADediting_912650(1285943, +), ADediting_912651(1285944, +), ADediting_912652(1285945, +), ADediting_912653(1285948, +), ADediting_912654(1285952, +), ADediting_912655(1285964, +), ADediting_912656(1285974, +), ADediting_912657(1286002, +), ADediting_912658(1286010, +), ADediting_912659(1286011, +), ADediting_912660(1287629, +), ADediting_912661(1288585, +), ADediting_912662(1288653, +), ADediting_912663(1288678, +), ADediting_912664(1288686, +), ADediting_912665(1288699, +), ADediting_912666(1288702, +), ADediting_912667(1288715, +), ADediting_912668(1288721, +), ADediting_912669(1288722, +), ADediting_912670(1288739, +), ADediting_912671(1288752, +), ADediting_912672(1288756, +), ADediting_912673(1288761, +), ADediting_912674(1288774, +), ADediting_912675(1288783, +), ADediting_912676(1288787, +), ADediting_912677(1288788, +), ADediting_912678(1288802, +), ADediting_912679(1288803, +), ADediting_912680(1288805, +), ADediting_912681(1288811, +), ADediting_912682(1288851, +), ADediting_912683(1288856, +), ADediting_912684(1288869, +), ADediting_912685(1288883, +), ADediting_912686(1288884, +), ADediting_912687(1288896, +), ADediting_912688(1289584, +), ADediting_912689(1289590, +), ADediting_912690(1289591, +), ADediting_912691(1289604, +), ADediting_912692(1289630, +), ADediting_912693(1289635, +), ADediting_912694(1289663, +), ADediting_912695(1289705, +), ADediting_912696(1289738, +), ADediting_912697(1289749, +), ADediting_912698(1289754, +), ADediting_912699(1289770, +), ADediting_912700(1289805, +), ADediting_912701(1289818, +), ADediting_912702(1290001, +), ADediting_912703(1290009, +), ADediting_912704(1290010, +), ADediting_912705(1290016, +), ADediting_912706(1290040, +), ADediting_912707(1290049, +), ADediting_912708(1290061, +), ADediting_912709(1290062, +), ADediting_912710(1290065, +), ADediting_912711(1290069, +), ADediting_912712(1290091, +), ADediting_912713(1290092, +), ADediting_912714(1290124, +), ADediting_912715(1290133, +), ADediting_912716(1290153, +), ADediting_912717(1290157, +), ADediting_912718(1290164, +), ADediting_912719(1290177, +), ADediting_912720(1290200, +), ADediting_912721(1293593, +), |
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RNA editing positional annotations for SNPH using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_912631 | chr20_1271381_+ | intronic |
| ADediting_912632 | chr20_1271403_+ | intronic |
| ADediting_912633 | chr20_1271416_+ | intronic |
| ADediting_912634 | chr20_1271441_+ | intronic |
| ADediting_912635 | chr20_1271442_+ | intronic |
| ADediting_912636 | chr20_1271443_+ | intronic |
| ADediting_912637 | chr20_1271471_+ | intronic |
| ADediting_912638 | chr20_1271525_+ | intronic |
| ADediting_912639 | chr20_1271539_+ | intronic |
| ADediting_912640 | chr20_1271542_+ | intronic |
| ADediting_912641 | chr20_1271547_+ | intronic |
| ADediting_912642 | chr20_1271551_+ | intronic |
| ADediting_912643 | chr20_1276051_+ | intronic |
| ADediting_912644 | chr20_1278818_+ | intronic |
| ADediting_912645 | chr20_1278823_+ | intronic |
| ADediting_912646 | chr20_1279689_+ | intronic |
| ADediting_912647 | chr20_1279697_+ | intronic |
| ADediting_912648 | chr20_1279702_+ | intronic |
| ADediting_912649 | chr20_1285919_+ | intronic |
| ADediting_912650 | chr20_1285943_+ | intronic |
| ADediting_912651 | chr20_1285944_+ | intronic |
| ADediting_912652 | chr20_1285945_+ | intronic |
| ADediting_912653 | chr20_1285948_+ | intronic |
| ADediting_912654 | chr20_1285952_+ | intronic |
| ADediting_912655 | chr20_1285964_+ | intronic |
| ADediting_912656 | chr20_1285974_+ | intronic |
| ADediting_912657 | chr20_1286002_+ | intronic |
| ADediting_912658 | chr20_1286010_+ | intronic |
| ADediting_912659 | chr20_1286011_+ | intronic |
| ADediting_912660 | chr20_1287629_+ | intronic |
| ADediting_912661 | chr20_1288585_+ | intronic |
| ADediting_912662 | chr20_1288653_+ | intronic |
| ADediting_912663 | chr20_1288678_+ | intronic |
| ADediting_912664 | chr20_1288686_+ | intronic |
| ADediting_912665 | chr20_1288699_+ | intronic |
| ADediting_912666 | chr20_1288702_+ | intronic |
| ADediting_912667 | chr20_1288715_+ | intronic |
| ADediting_912668 | chr20_1288721_+ | intronic |
| ADediting_912669 | chr20_1288722_+ | intronic |
| ADediting_912670 | chr20_1288739_+ | intronic |
| ADediting_912671 | chr20_1288752_+ | intronic |
| ADediting_912672 | chr20_1288756_+ | intronic |
| ADediting_912673 | chr20_1288761_+ | intronic |
| ADediting_912674 | chr20_1288774_+ | intronic |
| ADediting_912675 | chr20_1288783_+ | intronic |
| ADediting_912676 | chr20_1288787_+ | intronic |
| ADediting_912677 | chr20_1288788_+ | intronic |
| ADediting_912678 | chr20_1288802_+ | intronic |
| ADediting_912679 | chr20_1288803_+ | intronic |
| ADediting_912680 | chr20_1288805_+ | intronic |
| ADediting_912681 | chr20_1288811_+ | intronic |
| ADediting_912682 | chr20_1288851_+ | intronic |
| ADediting_912683 | chr20_1288856_+ | intronic |
| ADediting_912684 | chr20_1288869_+ | intronic |
| ADediting_912685 | chr20_1288883_+ | intronic |
| ADediting_912686 | chr20_1288884_+ | intronic |
| ADediting_912687 | chr20_1288896_+ | intronic |
| ADediting_912688 | chr20_1289584_+ | intronic |
| ADediting_912689 | chr20_1289590_+ | intronic |
| ADediting_912690 | chr20_1289591_+ | intronic |
| ADediting_912691 | chr20_1289604_+ | intronic |
| ADediting_912692 | chr20_1289630_+ | intronic |
| ADediting_912693 | chr20_1289635_+ | intronic |
| ADediting_912694 | chr20_1289663_+ | intronic |
| ADediting_912695 | chr20_1289705_+ | intronic |
| ADediting_912696 | chr20_1289738_+ | intronic |
| ADediting_912697 | chr20_1289749_+ | intronic |
| ADediting_912698 | chr20_1289754_+ | intronic |
| ADediting_912699 | chr20_1289770_+ | intronic |
| ADediting_912700 | chr20_1289805_+ | intronic |
| ADediting_912701 | chr20_1289818_+ | intronic |
| ADediting_912702 | chr20_1290001_+ | intronic |
| ADediting_912703 | chr20_1290009_+ | intronic |
| ADediting_912704 | chr20_1290010_+ | intronic |
| ADediting_912705 | chr20_1290016_+ | intronic |
| ADediting_912706 | chr20_1290040_+ | intronic |
| ADediting_912707 | chr20_1290049_+ | intronic |
| ADediting_912708 | chr20_1290061_+ | intronic |
| ADediting_912709 | chr20_1290062_+ | intronic |
| ADediting_912710 | chr20_1290065_+ | intronic |
| ADediting_912711 | chr20_1290069_+ | intronic |
| ADediting_912712 | chr20_1290091_+ | intronic |
| ADediting_912713 | chr20_1290092_+ | intronic |
| ADediting_912714 | chr20_1290124_+ | intronic |
| ADediting_912715 | chr20_1290133_+ | intronic |
| ADediting_912716 | chr20_1290153_+ | intronic |
| ADediting_912717 | chr20_1290157_+ | intronic |
| ADediting_912718 | chr20_1290164_+ | intronic |
| ADediting_912719 | chr20_1290177_+ | intronic |
| ADediting_912720 | chr20_1290200_+ | intronic |
| ADediting_912721 | chr20_1293593_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_912631 | chr20_1271381_+ | SINE | Alu | Name=AluSx |
| ADediting_912632 | chr20_1271403_+ | SINE | Alu | Name=AluSx |
| ADediting_912633 | chr20_1271416_+ | SINE | Alu | Name=AluSx |
| ADediting_912634 | chr20_1271441_+ | SINE | Alu | Name=AluSx |
| ADediting_912635 | chr20_1271442_+ | SINE | Alu | Name=AluSx |
| ADediting_912636 | chr20_1271443_+ | SINE | Alu | Name=AluSx |
| ADediting_912637 | chr20_1271471_+ | SINE | Alu | Name=AluSx |
| ADediting_912638 | chr20_1271525_+ | SINE | Alu | Name=AluSx |
| ADediting_912639 | chr20_1271539_+ | SINE | Alu | Name=AluSx |
| ADediting_912640 | chr20_1271542_+ | SINE | Alu | Name=AluSx |
| ADediting_912641 | chr20_1271547_+ | SINE | Alu | Name=AluSx |
| ADediting_912642 | chr20_1271551_+ | SINE | Alu | Name=AluSx |
| ADediting_912644 | chr20_1278818_+ | SINE | Alu | Name=AluSx3 |
| ADediting_912645 | chr20_1278823_+ | SINE | Alu | Name=AluSx3 |
| ADediting_912646 | chr20_1279689_+ | SINE | Alu | Name=AluJb |
| ADediting_912647 | chr20_1279697_+ | SINE | Alu | Name=AluJb |
| ADediting_912648 | chr20_1279702_+ | SINE | Alu | Name=AluJb |
| ADediting_912649 | chr20_1285919_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912650 | chr20_1285943_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912651 | chr20_1285944_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912652 | chr20_1285945_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912653 | chr20_1285948_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912654 | chr20_1285952_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912655 | chr20_1285964_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912656 | chr20_1285974_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912657 | chr20_1286002_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912658 | chr20_1286010_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912659 | chr20_1286011_+ | SINE | Alu | Name=AluSg4 |
| ADediting_912660 | chr20_1287629_+ | SINE | MIR | Name=MIR3 |
| ADediting_912662 | chr20_1288653_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912663 | chr20_1288678_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912664 | chr20_1288686_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912665 | chr20_1288699_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912666 | chr20_1288702_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912667 | chr20_1288715_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912668 | chr20_1288721_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912669 | chr20_1288722_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912670 | chr20_1288739_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912671 | chr20_1288752_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912672 | chr20_1288756_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912673 | chr20_1288761_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912674 | chr20_1288774_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912675 | chr20_1288783_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912676 | chr20_1288787_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912677 | chr20_1288788_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912678 | chr20_1288802_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912679 | chr20_1288803_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912680 | chr20_1288805_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912681 | chr20_1288811_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912682 | chr20_1288851_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912683 | chr20_1288856_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912684 | chr20_1288869_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912685 | chr20_1288883_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912686 | chr20_1288884_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912687 | chr20_1288896_+ | SINE | Alu | Name=AluSx1 |
| ADediting_912688 | chr20_1289584_+ | SINE | Alu | Name=AluJr |
| ADediting_912689 | chr20_1289590_+ | SINE | Alu | Name=AluJr |
| ADediting_912690 | chr20_1289591_+ | SINE | Alu | Name=AluJr |
| ADediting_912691 | chr20_1289604_+ | SINE | Alu | Name=AluJr |
| ADediting_912692 | chr20_1289630_+ | SINE | Alu | Name=AluJr |
| ADediting_912693 | chr20_1289635_+ | SINE | Alu | Name=AluJr |
| ADediting_912694 | chr20_1289663_+ | SINE | Alu | Name=AluJr |
| ADediting_912695 | chr20_1289705_+ | SINE | Alu | Name=AluJr |
| ADediting_912696 | chr20_1289738_+ | SINE | Alu | Name=AluJr |
| ADediting_912697 | chr20_1289749_+ | SINE | Alu | Name=AluJr |
| ADediting_912698 | chr20_1289754_+ | SINE | Alu | Name=AluJr |
| ADediting_912699 | chr20_1289770_+ | SINE | Alu | Name=AluJr |
| ADediting_912700 | chr20_1289805_+ | SINE | Alu | Name=AluJr |
| ADediting_912701 | chr20_1289818_+ | SINE | Alu | Name=AluJr |
| ADediting_912702 | chr20_1290001_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912703 | chr20_1290009_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912704 | chr20_1290010_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912705 | chr20_1290016_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912706 | chr20_1290040_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912707 | chr20_1290049_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912708 | chr20_1290061_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912709 | chr20_1290062_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912710 | chr20_1290065_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912711 | chr20_1290069_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912712 | chr20_1290091_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912713 | chr20_1290092_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912714 | chr20_1290124_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912715 | chr20_1290133_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912716 | chr20_1290153_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912717 | chr20_1290157_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912718 | chr20_1290164_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912719 | chr20_1290177_+ | SINE | Alu | Name=AluSz6 |
| ADediting_912720 | chr20_1290200_+ | SINE | Alu | Name=AluSz6 |
Top |
RNA A-to-I editing events in the alternative splicing sites for SNPH |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for SNPH |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for SNPH |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for SNPH |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-151a-3p | chr20 | 1308890 | 1308896 | 7mer-m8 | 1308877 | 1308897 | 140 | -17.87 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-151a-3p | chr20 | 1308890 | 1308896 | 7mer-m8 | 1308877 | 1308897 | 140 | -17.87 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-151a-3p | chr20 | 1308890 | 1308896 | 7mer-m8 | 1308877 | 1308897 | 140 | -17.87 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-4477b | chr20 | 1306524 | 1306531 | 8mer-1a | 1306510 | 1306531 | 142 | -11.4 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-4477b | chr20 | 1306524 | 1306531 | 8mer-1a | 1306510 | 1306531 | 142 | -11.4 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-4477b | chr20 | 1306524 | 1306531 | 8mer-1a | 1306510 | 1306531 | 142 | -11.4 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000101298.15 | ENST00000649598.1 | SNPH-204 | hsa-miR-4477b | chr20 | 1306524 | 1306531 | 8mer-1a | 1306510 | 1306531 | 142 | -11.4 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-4512 | chr20 | 1306423 | 1306429 | 7mer-m8 | 1306409 | 1306430 | 143 | -15.13 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-4512 | chr20 | 1307512 | 1307519 | 8mer-1a | 1307495 | 1307519 | 142 | -18.03 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-4512 | chr20 | 1308089 | 1308095 | 7mer-m8 | 1308075 | 1308096 | 142 | -13.6 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-4512 | chr20 | 1306423 | 1306429 | 7mer-m8 | 1306409 | 1306430 | 143 | -15.13 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-4512 | chr20 | 1307512 | 1307519 | 8mer-1a | 1307495 | 1307519 | 142 | -18.03 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-4512 | chr20 | 1308089 | 1308095 | 7mer-m8 | 1308075 | 1308096 | 142 | -13.6 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-4512 | chr20 | 1306423 | 1306429 | 7mer-m8 | 1306409 | 1306430 | 143 | -15.13 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-4512 | chr20 | 1307512 | 1307519 | 8mer-1a | 1307495 | 1307519 | 142 | -18.03 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-4512 | chr20 | 1308089 | 1308095 | 7mer-m8 | 1308075 | 1308096 | 142 | -13.6 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000649598.1 | SNPH-204 | hsa-miR-4512 | chr20 | 1306423 | 1306429 | 7mer-m8 | 1306409 | 1306430 | 143 | -15.13 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-589-3p | chr20 | 1308285 | 1308291 | 7mer-m8 | 1308266 | 1308292 | 146 | -15.96 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-589-3p | chr20 | 1308285 | 1308291 | 7mer-m8 | 1308266 | 1308292 | 146 | -15.96 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-589-3p | chr20 | 1308285 | 1308291 | 7mer-m8 | 1308266 | 1308292 | 146 | -15.96 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-589-5p | chr20 | 1307099 | 1307106 | 8mer-1a | 1307085 | 1307106 | 148 | -18.95 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-589-5p | chr20 | 1307099 | 1307106 | 8mer-1a | 1307085 | 1307106 | 148 | -18.95 |
| ADediting_1337758 | chr7_5495892_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-589-5p | chr20 | 1307099 | 1307106 | 8mer-1a | 1307085 | 1307106 | 148 | -18.95 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-151a-3p | chr20 | 1308175 | 1308181 | 7mer-m8 | 1308162 | 1308182 | 155 | -18.04 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-151a-3p | chr20 | 1308175 | 1308181 | 7mer-m8 | 1308162 | 1308182 | 155 | -18.04 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-151a-3p | chr20 | 1308175 | 1308181 | 7mer-m8 | 1308162 | 1308182 | 155 | -18.04 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-641 | chr20 | 1307544 | 1307550 | 7mer-1a | 1307527 | 1307550 | 142 | -23.88 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-641 | chr20 | 1307544 | 1307550 | 7mer-1a | 1307527 | 1307550 | 142 | -23.88 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-641 | chr20 | 1307544 | 1307550 | 7mer-1a | 1307527 | 1307550 | 142 | -23.88 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-641 | chr20 | 1307544 | 1307550 | 7mer-1a | 1307527 | 1307550 | 142 | -23.88 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-641 | chr20 | 1307544 | 1307550 | 7mer-1a | 1307527 | 1307550 | 142 | -23.88 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-641 | chr20 | 1307544 | 1307550 | 7mer-1a | 1307527 | 1307550 | 142 | -23.88 |
| ADediting_291761 | chr11_93733708_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-1304-3p | chr20 | 1307123 | 1307129 | 7mer-m8 | 1307109 | 1307130 | 155 | -19.18 |
| ADediting_291761 | chr11_93733708_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-1304-3p | chr20 | 1307123 | 1307129 | 7mer-m8 | 1307109 | 1307130 | 155 | -19.18 |
| ADediting_291761 | chr11_93733708_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-1304-3p | chr20 | 1307123 | 1307129 | 7mer-m8 | 1307109 | 1307130 | 155 | -19.18 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381867.6 | SNPH-201 | hsa-miR-4512 | chr20 | 1308431 | 1308437 | 7mer-m8 | 1308418 | 1308438 | 141 | -20.86 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000381873.7 | SNPH-202 | hsa-miR-4512 | chr20 | 1308431 | 1308437 | 7mer-m8 | 1308418 | 1308438 | 141 | -20.86 |
| ADediting_496066 | chr15_66496985_- | ENSG00000101298.15 | ENST00000614659.1 | SNPH-203 | hsa-miR-4512 | chr20 | 1308431 | 1308437 | 7mer-m8 | 1308418 | 1308438 | 141 | -20.86 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for SNPH |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for SNPH |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_912631 | chr20_1271381_+ | 0.104990572794772 | 0.132888342220319 | 0.000153003778098033 | 0.304318091639871 | 0.344610807130153 | 0.077699872593156 |
| CER | ADediting_912641 | chr20_1271547_+ | 5.64341648340851e-05 | 0.322682508334573 | 1.96431188732759e-08 | 0.438686655779163 | 0.0713891878523213 | 0.147641064792487 |
| TCX | ADediting_912641 | chr20_1271547_+ | 0.0147105583218312 | 0.198848639201538 | 5.97143132390469e-05 | 0.321673485064843 | 0.225395083191091 | -0.099571177008176 |
| CER | ADediting_912642 | chr20_1271551_+ | 0.00162139596337653 | 0.255221285951154 | 2.69073218488299e-07 | 0.405229143905141 | 0.0240148735715717 | 0.18423526653833 |
| CER | ADediting_912649 | chr20_1285919_+ | 0.0207985111061509 | 0.188623559640862 | 4.54872555312688e-05 | 0.326501408471799 | 0.395139287867255 | 0.0699294451454907 |
| CER | ADediting_912663 | chr20_1288678_+ | 0.00127895790318019 | 0.260587159728906 | 8.66342097931717e-06 | 0.354297594416937 | 0.25231433138643 | 0.0940475530379357 |
| CER | ADediting_912665 | chr20_1288699_+ | 0.000322127426060699 | 0.289776656918817 | 1.37817260168558e-06 | 0.382331707317184 | 0.202610577732064 | 0.104623300028792 |
| CER | ADediting_912666 | chr20_1288702_+ | 0.000765329485161686 | 0.27183570622222 | 6.04426551465079e-06 | 0.359998826141186 | 0.099242657465562 | 0.135114754369307 |
| CER | ADediting_912667 | chr20_1288715_+ | 0.00135395902902845 | 0.259308373428009 | 2.62347455388696e-06 | 0.372810710834008 | 0.21495622340692 | 0.10183827259205 |
| CER | ADediting_912668 | chr20_1288721_+ | 0.00481663755177991 | 0.229022675494498 | 4.77086924661998e-06 | 0.36368674221756 | 0.458801467767524 | 0.0609414021692845 |
| CER | ADediting_912669 | chr20_1288722_+ | 0.000253362925890496 | 0.294551253970632 | 8.50051493717683e-06 | 0.354600981506954 | 0.080886248118742 | 0.142987795261713 |
| CER | ADediting_912671 | chr20_1288752_+ | 0.00124682533048005 | 0.261156111092539 | 5.22959197403751e-07 | 0.396121153384139 | 2.2298736933279e-05 | 0.338777385541948 |
| CER | ADediting_912673 | chr20_1288761_+ | 0.0151626130196604 | 0.197973366697517 | 8.22576322459137e-05 | 0.315884625894473 | 0.504332643185044 | 0.0549348809735645 |
| CER | ADediting_912675 | chr20_1288783_+ | 0.00072991992564252 | 0.272849591586735 | 6.93012629111731e-07 | 0.392178745124949 | 0.332552543794719 | 0.079657881686039 |
| CER | ADediting_912676 | chr20_1288787_+ | 0.0042751450197112 | 0.232030841071253 | 0.000143610622112145 | 0.305521029566989 | 0.141268416938405 | 0.120683609852395 |
| CER | ADediting_912679 | chr20_1288803_+ | 0.00193246630725541 | 0.251178266864915 | 4.2420278012371e-06 | 0.36550133702611 | 0.0040019341417467 | 0.233680857211059 |
| CER | ADediting_912681 | chr20_1288811_+ | 0.00665548232003142 | 0.220672971829121 | 0.000165181001420173 | 0.302857138104704 | 0.00969672527185023 | 0.210571813060893 |
| CER | ADediting_912683 | chr20_1288856_+ | 0.000442943880555674 | 0.283311768787283 | 9.51359374848548e-06 | 0.352796902400601 | 0.047860933930911 | 0.161839331331027 |
| CER | ADediting_912687 | chr20_1288896_+ | 0.00264653387855213 | 0.243769665074885 | 4.03694808422154e-06 | 0.366263379423279 | 0.141359659064708 | 0.120656137639538 |
| CER | ADediting_912695 | chr20_1289705_+ | 0.0132729265335022 | 0.201797552157234 | 2.66174233839492e-05 | 0.335777169596793 | 0.00511014416800666 | 0.227516731868452 |
| CER | ADediting_912696 | chr20_1289738_+ | 0.000683718629583751 | 0.274242747942495 | 6.22712084221e-07 | 0.393682555972628 | 0.0318291816127015 | 0.175371450558007 |
| CER | ADediting_912697 | chr20_1289749_+ | 0.000630969155527014 | 0.275943457853153 | 1.58965247426434e-05 | 0.344428063278011 | 0.358578699103869 | 0.0754851013934783 |
| CER | ADediting_912698 | chr20_1289754_+ | 0.000312712695891314 | 0.290370993081709 | 5.05604781338658e-08 | 0.427014749532507 | 0.481677294910831 | 0.0578853459884643 |
| CER | ADediting_912700 | chr20_1289805_+ | 0.00197383699408653 | 0.250685955061756 | 3.10168726409523e-06 | 0.370283940920563 | 0.746542774666986 | 0.0266071862610028 |
| CER | ADediting_912702 | chr20_1290001_+ | 0.0364647483054856 | 0.170957896924691 | 7.49857787770697e-05 | 0.317569687245862 | 0.148092300188497 | 0.11866514441217 |
| CER | ADediting_912703 | chr20_1290009_+ | 0.0232894129791039 | 0.185178819554298 | 6.51664522569127e-05 | 0.320105954274236 | 0.070596095008677 | 0.148051897804871 |
| CER | ADediting_912704 | chr20_1290010_+ | 0.0326666076727736 | 0.174535525099781 | 5.51484689498072e-06 | 0.361433181727498 | 0.314436289279277 | 0.0826870030193578 |
| CER | ADediting_912705 | chr20_1290016_+ | 0.0141221966303466 | 0.200023675615098 | 2.68230012066857e-06 | 0.37247730933675 | 0.528955380511753 | 0.0518055838450298 |
| CER | ADediting_912708 | chr20_1290061_+ | 0.00122669428589415 | 0.261519425789611 | 1.11875781539463e-07 | 0.416857152876425 | 0.112493786336336 | 0.130121773142692 |
| CER | ADediting_912709 | chr20_1290062_+ | 0.00426667849169366 | 0.232080532689503 | 6.04306051243382e-07 | 0.394103045443254 | 0.172758871713301 | 0.111906680647043 |
| CER | ADediting_912710 | chr20_1290065_+ | 0.0144285957757105 | 0.199406534475923 | 1.71016458384438e-05 | 0.343217188207961 | 0.0689551932564045 | 0.148913950402589 |
| CER | ADediting_912711 | chr20_1290069_+ | 0.0299132456353322 | 0.177356541134224 | 0.000147555471799849 | 0.305007153356347 | 0.0567128925708082 | 0.155936162222404 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.74108506683875e-41 | 0.667173629047374 | 1.48004500645791e-69 | 0.797476065691547 | 2.16616029038127e-08 | 0.311278747435852 |
| AC | 4.28370920685255e-47 | 0.753625672815648 | 2.53931538375885e-60 | 0.813533403600528 | 3.3267300922983e-08 | 0.34053499303477 |
| PCC | 1.89796419162227e-46 | 0.813915709760999 | 1.7249801428202e-57 | 0.861352046758173 | 0.000276912459021933 | 0.260251357284412 |
| CER | 1.5591682353029e-14 | 0.574237096759216 | 5.06623765108532e-22 | 0.683991093597283 | 0.0171983603721532 | 0.194293220236111 |
| TCX | 1.16657004767356e-14 | 0.576486419590666 | 1.80553048852138e-29 | 0.759828973257009 | 0.00457775136911012 | -0.23031031398762 |
| FP | 2.788357016803e-28 | 0.707021086615097 | 2.26118118267315e-21 | 0.633646031789026 | 5.53619991521416e-08 | 0.393459071530103 |
| IFG | 1.43711560390804e-06 | 0.801927210219979 | 4.48928687825673e-08 | 0.85708606528226 | 0.412478205984594 | 0.171467391486593 |
| PG | 0.0683412562952337 | 0.133950565841052 | 3.42175599232804e-06 | 0.332972549834848 | 0.606231433741653 | -0.0380381236255941 |
| STG | 6.80611590809344e-27 | 0.869896998246799 | 1.00668380559404e-20 | 0.810276803471007 | 0.34902719667215 | 0.103453739730199 |
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Relation with AD stages for SNPH |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_912631 | chr20_1271381_+ | 0.00117730315313851 | 0.30813790384925 |
| CER | ADediting_912641 | chr20_1271547_+ | 0.000288517130186122 | 0.342240250468834 |
| IFG | ADediting_912675 | chr20_1288783_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_912676 | chr20_1288787_+ | 0.0354713369979928 | 0.422303326441651 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.00106088889721259 | 0.310803806178033 |
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RelatedDrugs for SNPH |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SNPH |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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