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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for HERPUD1 |
 Gene summary |
| Gene information | Gene symbol | HERPUD1 | Gene ID | 9709 |
| Gene name | homocysteine inducible ER protein with ubiquitin like domain 1 | |
| Synonyms | HERP|Mif1|SUP | |
| Cytomap | 16q13 | |
| Type of gene | protein-coding | |
| Description | homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 proteinMMS-induciblehomocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 proteinhomocysteine-inducible, endoplasmic reticulum | |
| Modification date | 20200313 | |
| UniProtAcc | Q15011, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| HERPUD1 | GO:0032469 | endoplasmic reticulum calcium ion homeostasis | 15102845|22045699 |
| HERPUD1 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | 15102845 |
| HERPUD1 | GO:1903071 | positive regulation of ER-associated ubiquitin-dependent protein catabolic process | 22045699 |
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RNA A-to-I events for HERPUD1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_546958(56940367, +), ADediting_546959(56940370, +), ADediting_546960(56940387, +), ADediting_546961(56940406, +), ADediting_546962(56940407, +), ADediting_546963(56940424, +), ADediting_546964(56940446, +), ADediting_546965(56940448, +), ADediting_546966(56940472, +), ADediting_546967(56940473, +), ADediting_546968(56940479, +), ADediting_546969(56940487, +), ADediting_546970(56940490, +), ADediting_546971(56940516, +), ADediting_546972(56940541, +), ADediting_546973(56940553, +), ADediting_546974(56940568, +), ADediting_546975(56940580, +), ADediting_546976(56940700, +), ADediting_546977(56940706, +), ADediting_546978(56940707, +), ADediting_546979(56940733, +), ADediting_546980(56940742, +), ADediting_546981(56940747, +), ADediting_546982(56940752, +), ADediting_546983(56940755, +), ADediting_546984(56940784, +), ADediting_546985(56940786, +), ADediting_546986(56940800, +), ADediting_546987(56940801, +), ADediting_546988(56940804, +), ADediting_546989(56940808, +), ADediting_546990(56940809, +), ADediting_546991(56940810, +), ADediting_546992(56940811, +), ADediting_546993(56940812, +), ADediting_546994(56940813, +), ADediting_546995(56940816, +), ADediting_546996(56940859, +), ADediting_546997(56940860, +), ADediting_546998(56940864, +), ADediting_546999(56940870, +), ADediting_547000(56940878, +), ADediting_547001(56940879, +), ADediting_547002(56940890, +), ADediting_547003(56940945, +), ADediting_547004(56941954, +), ADediting_547005(56942724, +), ADediting_547006(56942754, +), ADediting_1543107(56940339, +), ADediting_1543108(56940400, +), ADediting_1543109(56940459, +), ADediting_1543110(56940481, +), ADediting_1543111(56940698, +), ADediting_1543112(56940797, +), ADediting_1543113(56940923, +), ADediting_1543114(56944546, +), ADediting_1543115(56944702, +), ADediting_1624770(56940567, +), ADediting_1624771(56940946, +), |
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RNA editing positional annotations for HERPUD1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_546958 | chr16_56940367_+ | ncRNA_exonic |
| ADediting_546959 | chr16_56940370_+ | ncRNA_exonic |
| ADediting_546960 | chr16_56940387_+ | ncRNA_exonic |
| ADediting_546961 | chr16_56940406_+ | ncRNA_intronic |
| ADediting_546962 | chr16_56940407_+ | ncRNA_intronic |
| ADediting_546963 | chr16_56940424_+ | ncRNA_intronic |
| ADediting_546964 | chr16_56940446_+ | ncRNA_intronic |
| ADediting_546965 | chr16_56940448_+ | ncRNA_intronic |
| ADediting_546966 | chr16_56940472_+ | ncRNA_intronic |
| ADediting_546967 | chr16_56940473_+ | ncRNA_intronic |
| ADediting_546968 | chr16_56940479_+ | ncRNA_intronic |
| ADediting_546969 | chr16_56940487_+ | ncRNA_intronic |
| ADediting_546970 | chr16_56940490_+ | ncRNA_intronic |
| ADediting_546971 | chr16_56940516_+ | ncRNA_intronic |
| ADediting_546972 | chr16_56940541_+ | ncRNA_intronic |
| ADediting_546973 | chr16_56940553_+ | ncRNA_intronic |
| ADediting_546974 | chr16_56940568_+ | ncRNA_intronic |
| ADediting_546975 | chr16_56940580_+ | ncRNA_intronic |
| ADediting_546976 | chr16_56940700_+ | ncRNA_intronic |
| ADediting_546977 | chr16_56940706_+ | ncRNA_intronic |
| ADediting_546978 | chr16_56940707_+ | ncRNA_intronic |
| ADediting_546979 | chr16_56940733_+ | ncRNA_intronic |
| ADediting_546980 | chr16_56940742_+ | ncRNA_intronic |
| ADediting_546981 | chr16_56940747_+ | ncRNA_intronic |
| ADediting_546982 | chr16_56940752_+ | ncRNA_intronic |
| ADediting_546983 | chr16_56940755_+ | ncRNA_intronic |
| ADediting_546984 | chr16_56940784_+ | ncRNA_intronic |
| ADediting_546985 | chr16_56940786_+ | ncRNA_intronic |
| ADediting_546986 | chr16_56940800_+ | ncRNA_intronic |
| ADediting_546987 | chr16_56940801_+ | ncRNA_intronic |
| ADediting_546988 | chr16_56940804_+ | ncRNA_intronic |
| ADediting_546989 | chr16_56940808_+ | ncRNA_intronic |
| ADediting_546990 | chr16_56940809_+ | ncRNA_intronic |
| ADediting_546991 | chr16_56940810_+ | ncRNA_intronic |
| ADediting_546992 | chr16_56940811_+ | ncRNA_intronic |
| ADediting_546993 | chr16_56940812_+ | ncRNA_intronic |
| ADediting_546994 | chr16_56940813_+ | ncRNA_intronic |
| ADediting_546995 | chr16_56940816_+ | ncRNA_intronic |
| ADediting_546996 | chr16_56940859_+ | ncRNA_intronic |
| ADediting_546997 | chr16_56940860_+ | ncRNA_intronic |
| ADediting_546998 | chr16_56940864_+ | ncRNA_splicing |
| ADediting_546999 | chr16_56940870_+ | ncRNA_exonic |
| ADediting_547000 | chr16_56940878_+ | ncRNA_exonic |
| ADediting_547001 | chr16_56940879_+ | ncRNA_exonic |
| ADediting_547002 | chr16_56940890_+ | ncRNA_exonic |
| ADediting_547003 | chr16_56940945_+ | ncRNA_exonic |
| ADediting_547004 | chr16_56941954_+ | intronic |
| ADediting_547005 | chr16_56942724_+ | intronic |
| ADediting_547006 | chr16_56942754_+ | intronic |
| ADediting_1543107 | chr16_56940339_+ | ncRNA_exonic |
| ADediting_1543108 | chr16_56940400_+ | ncRNA_exonic |
| ADediting_1543109 | chr16_56940459_+ | ncRNA_intronic |
| ADediting_1543110 | chr16_56940481_+ | ncRNA_intronic |
| ADediting_1543111 | chr16_56940698_+ | ncRNA_intronic |
| ADediting_1543112 | chr16_56940797_+ | ncRNA_intronic |
| ADediting_1543113 | chr16_56940923_+ | ncRNA_exonic |
| ADediting_1543114 | chr16_56944546_+ | UTR3 |
| ADediting_1543115 | chr16_56944702_+ | UTR3 |
| ADediting_1624770 | chr16_56940567_+ | ncRNA_intronic |
| ADediting_1624771 | chr16_56940946_+ | ncRNA_exonic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_546958 | chr16_56940367_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546959 | chr16_56940370_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546960 | chr16_56940387_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546961 | chr16_56940406_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546962 | chr16_56940407_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546963 | chr16_56940424_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546964 | chr16_56940446_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546965 | chr16_56940448_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546966 | chr16_56940472_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546967 | chr16_56940473_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546968 | chr16_56940479_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546969 | chr16_56940487_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546970 | chr16_56940490_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546971 | chr16_56940516_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546972 | chr16_56940541_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546973 | chr16_56940553_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546974 | chr16_56940568_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546975 | chr16_56940580_+ | SINE | Alu | Name=AluSx1 |
| ADediting_546976 | chr16_56940700_+ | SINE | Alu | Name=AluSx |
| ADediting_546977 | chr16_56940706_+ | SINE | Alu | Name=AluSx |
| ADediting_546978 | chr16_56940707_+ | SINE | Alu | Name=AluSx |
| ADediting_546979 | chr16_56940733_+ | SINE | Alu | Name=AluSx |
| ADediting_546980 | chr16_56940742_+ | SINE | Alu | Name=AluSx |
| ADediting_546981 | chr16_56940747_+ | SINE | Alu | Name=AluSx |
| ADediting_546982 | chr16_56940752_+ | SINE | Alu | Name=AluSx |
| ADediting_546983 | chr16_56940755_+ | SINE | Alu | Name=AluSx |
| ADediting_546984 | chr16_56940784_+ | SINE | Alu | Name=AluSx |
| ADediting_546985 | chr16_56940786_+ | SINE | Alu | Name=AluSx |
| ADediting_546986 | chr16_56940800_+ | SINE | Alu | Name=AluSx |
| ADediting_546987 | chr16_56940801_+ | SINE | Alu | Name=AluSx |
| ADediting_546988 | chr16_56940804_+ | SINE | Alu | Name=AluSx |
| ADediting_546989 | chr16_56940808_+ | SINE | Alu | Name=AluSx |
| ADediting_546990 | chr16_56940809_+ | SINE | Alu | Name=AluSx |
| ADediting_546991 | chr16_56940810_+ | SINE | Alu | Name=AluSx |
| ADediting_546992 | chr16_56940811_+ | SINE | Alu | Name=AluSx |
| ADediting_546993 | chr16_56940812_+ | SINE | Alu | Name=AluSx |
| ADediting_546994 | chr16_56940813_+ | SINE | Alu | Name=AluSx |
| ADediting_546995 | chr16_56940816_+ | SINE | Alu | Name=AluSx |
| ADediting_546996 | chr16_56940859_+ | SINE | Alu | Name=AluSx |
| ADediting_546997 | chr16_56940860_+ | SINE | Alu | Name=AluSx |
| ADediting_546998 | chr16_56940864_+ | SINE | Alu | Name=AluSx |
| ADediting_546999 | chr16_56940870_+ | SINE | Alu | Name=AluSx |
| ADediting_547000 | chr16_56940878_+ | SINE | Alu | Name=AluSx |
| ADediting_547001 | chr16_56940879_+ | SINE | Alu | Name=AluSx |
| ADediting_547002 | chr16_56940890_+ | SINE | Alu | Name=AluSx |
| ADediting_547003 | chr16_56940945_+ | SINE | Alu | Name=AluSx |
| ADediting_547004 | chr16_56941954_+ | LINE | L2 | Name=L2c |
| ADediting_547005 | chr16_56942724_+ | SINE | Alu | Name=AluSx |
| ADediting_547006 | chr16_56942754_+ | SINE | Alu | Name=AluSx |
| ADediting_1543107 | chr16_56940339_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1543108 | chr16_56940400_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1543109 | chr16_56940459_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1543110 | chr16_56940481_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1543111 | chr16_56940698_+ | SINE | Alu | Name=AluSx |
| ADediting_1543112 | chr16_56940797_+ | SINE | Alu | Name=AluSx |
| ADediting_1543113 | chr16_56940923_+ | SINE | Alu | Name=AluSx |
| ADediting_1543114 | chr16_56944546_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1543115 | chr16_56944702_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1624770 | chr16_56940567_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1624771 | chr16_56940946_+ | SINE | Alu | Name=AluSx |
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RNA A-to-I editing events in the alternative splicing sites for HERPUD1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HERPUD1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for HERPUD1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for HERPUD1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1543114 | chr16_56944546_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-17-3p | chr16 | 56944539 | 56944545 | 7mer-m8 | 56944525 | 56944546 | 150 | -17.74 |
| ADediting_1543114 | chr16_56944546_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-485-5p | chr16 | 56944543 | 56944549 | 7mer-m8 | 56944530 | 56944550 | 153 | -20.87 |
| ADediting_1543114 | chr16_56944546_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-6884-5p | chr16 | 56944543 | 56944549 | 7mer-m8 | 56944527 | 56944550 | 150 | -25.7 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1543114 | chr16_56944546_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-377-5p | chr16 | 56944543 | 56944549 | 7mer-m8 | 56944527 | 56944550 | 150 | -19.39 |
| ADediting_1543114 | chr16_56944546_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-6086 | chr16 | 56944543 | 56944549 | 7mer-m8 | 56944531 | 56944550 | 150 | -21.06 |
| ADediting_1543114 | chr16_56944546_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-6516-5p | chr16 | 56944539 | 56944545 | 7mer-m8 | 56944524 | 56944546 | 144 | -14.69 |
| ADediting_1543115 | chr16_56944702_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-3622a-3p | chr16 | 56944699 | 56944706 | 8mer-1a | 56944685 | 56944706 | 144 | -13.55 |
| ADediting_1543115 | chr16_56944702_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-3622b-3p | chr16 | 56944699 | 56944706 | 8mer-1a | 56944686 | 56944706 | 153 | -18.56 |
| ADediting_1543115 | chr16_56944702_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-7162-3p | chr16 | 56944696 | 56944702 | 7mer-m8 | 56944685 | 56944703 | 140 | -14.93 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_286380 | chr11_79422188_- | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-5579-3p | chr16 | 56944142 | 56944148 | 7mer-m8 | 56944128 | 56944149 | 150 | -16.81 |
| ADediting_496066 | chr15_66496985_- | ENSG00000051108.15 | ENST00000568358.1 | HERPUD1-213 | hsa-miR-4512 | chr16 | 56943265 | 56943271 | 7mer-m8 | 56943252 | 56943272 | 145 | -17.11 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-5585-3p | chr16 | 56944094 | 56944100 | 7mer-m8 | 56944078 | 56944101 | 151 | -19.48 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-5688 | chr16 | 56943916 | 56943922 | 7mer-m8 | 56943901 | 56943923 | 152 | -15.28 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000051108.15 | ENST00000300302.9 | HERPUD1-201 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000051108.15 | ENST00000344114.8 | HERPUD1-202 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000051108.15 | ENST00000379792.6 | HERPUD1-203 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000051108.15 | ENST00000563911.5 | HERPUD1-208 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000051108.15 | ENST00000568358.1 | HERPUD1-213 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000051108.15 | ENST00000300302.9 | HERPUD1-201 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000051108.15 | ENST00000344114.8 | HERPUD1-202 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000051108.15 | ENST00000379792.6 | HERPUD1-203 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000051108.15 | ENST00000563911.5 | HERPUD1-208 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000051108.15 | ENST00000568358.1 | HERPUD1-213 | hsa-miR-641 | chr16 | 56943491 | 56943497 | 7mer-m8 | 56943476 | 56943498 | 149 | -15.14 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000051108.15 | ENST00000300302.9 | HERPUD1-201 | hsa-miR-1273h-3p | chr16 | 56943605 | 56943611 | 7mer-m8 | 56943590 | 56943612 | 146 | -14.13 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000051108.15 | ENST00000344114.8 | HERPUD1-202 | hsa-miR-1273h-3p | chr16 | 56943605 | 56943611 | 7mer-m8 | 56943590 | 56943612 | 146 | -14.13 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000051108.15 | ENST00000379792.6 | HERPUD1-203 | hsa-miR-1273h-3p | chr16 | 56943605 | 56943611 | 7mer-m8 | 56943590 | 56943612 | 146 | -14.13 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000051108.15 | ENST00000439977.7 | HERPUD1-204 | hsa-miR-1273h-3p | chr16 | 56943605 | 56943611 | 7mer-m8 | 56943590 | 56943612 | 146 | -14.13 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for HERPUD1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000439977.7 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1543114 | ENST00000439977.7 | chr16_56944546_+ | 2535 | -902.40 | -901.00 | -903.80 |
| ADediting_1543115 | ENST00000439977.7 | chr16_56944702_+ | 2691 | -902.40 | -901.00 | -903.80 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for HERPUD1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_546958 | chr16_56940367_+ | 4.54309438414904e-05 | 0.22944266911428 | 0.00335959168789954 | 0.166082402635658 | 1.95469148120633e-10 | 0.35133011393001 |
| CER | ADediting_546958 | chr16_56940367_+ | 7.54725441254763e-05 | 0.3174522144001 | 0.00123620732892384 | 0.26134706545151 | 0.350436265818999 | 0.0767694571109109 |
| TCX | ADediting_546958 | chr16_56940367_+ | 0.470386226762374 | 0.059383599025165 | 0.306986705317031 | -0.0839654657957835 | 0.000144642386955244 | 0.305385368057976 |
| DLPFC | ADediting_546959 | chr16_56940370_+ | 0.00118549287261792 | 0.183330369227579 | 0.100315078736302 | 0.0935079091635349 | 1.57161204576701e-08 | 0.314201473372651 |
| CER | ADediting_546961 | chr16_56940406_+ | 7.63865400989324e-05 | 0.317233539607235 | 0.0161371931107851 | 0.196161178314159 | 0.989716204613011 | -0.00106127518681623 |
| DLPFC | ADediting_546962 | chr16_56940407_+ | 2.45519650271814e-07 | 0.288057214685322 | 0.000513091028890203 | 0.196172148588252 | 7.41776209390586e-09 | 0.320920030473672 |
| CER | ADediting_546962 | chr16_56940407_+ | 6.51457330576454e-09 | 0.451778358384511 | 1.84795206111019e-05 | 0.341927661165671 | 0.453677504767583 | 0.0616373619418567 |
| DLPFC | ADediting_546964 | chr16_56940446_+ | 0.000244174262102789 | 0.206921740114563 | 0.251165344843304 | 0.0653692977065631 | 3.28923415760814e-15 | 0.427575730791093 |
| DLPFC | ADediting_546968 | chr16_56940479_+ | 2.71458293484071e-05 | 0.235907577234938 | 0.100398342224671 | 0.0934851058083547 | 1.87846318729854e-19 | 0.482157344476461 |
| CER | ADediting_546968 | chr16_56940479_+ | 1.79300152202116e-05 | 0.342430696739589 | 8.97088312237515e-06 | 0.353739414231416 | 0.638384090696712 | 0.0386812368286968 |
| DLPFC | ADediting_546970 | chr16_56940490_+ | 4.84487793556063e-06 | 0.256322735077724 | 0.0341271502414093 | 0.1203748954719 | 1.56866815996047e-16 | 0.445647037040469 |
| DLPFC | ADediting_546971 | chr16_56940516_+ | 0.000113772485683545 | 0.217436480063689 | 0.0763569620698266 | 0.100806391135643 | 3.62382573817646e-11 | 0.364385957125681 |
| DLPFC | ADediting_546972 | chr16_56940541_+ | 1.63749257111569e-05 | 0.242081369274181 | 0.0131063536815599 | 0.140770100132365 | 1.64692402058223e-10 | 0.352684876697551 |
| DLPFC | ADediting_546973 | chr16_56940553_+ | 0.000461814158928824 | 0.197730600014889 | 0.0690584792944991 | 0.103398339288431 | 2.94986107356762e-13 | 0.398721293636109 |
| CER | ADediting_546973 | chr16_56940553_+ | 3.44764329984942e-07 | 0.401863355768378 | 3.97952920226653e-06 | 0.366483321622091 | 0.118516218843428 | 0.128003627275785 |
| DLPFC | ADediting_546974 | chr16_56940568_+ | 0.0465823475185388 | 0.113122764321878 | 0.851562842909703 | -0.010670774958793 | 6.72847190581856e-16 | 0.437133869187969 |
| DLPFC | ADediting_546976 | chr16_56940700_+ | 0.0144367070126983 | 0.138822809923319 | 0.703384855132199 | 0.0217106023225256 | 2.48736644404773e-16 | 0.442977542321225 |
| DLPFC | ADediting_546979 | chr16_56940733_+ | 0.0437353943239586 | 0.11462149800559 | 0.647145627101604 | -0.026098382975396 | 1.55108163618929e-20 | 0.494655091493838 |
| CER | ADediting_546987 | chr16_56940801_+ | 0.00193384805035844 | 0.251161670164856 | 0.000171847684058842 | 0.30209927989081 | 0.33715063992585 | 0.0789060058422547 |
| CER | ADediting_546995 | chr16_56940816_+ | 9.14689124906706e-05 | 0.313939802849439 | 6.71153671157019e-05 | 0.319575321711043 | 0.516412844549886 | 0.0533900474249209 |
| DLPFC | ADediting_546996 | chr16_56940859_+ | 0.00136810302921037 | 0.181047998051166 | 0.567123352026751 | 0.0326272206229169 | 1.76609094217358e-15 | 0.431357491440073 |
| CER | ADediting_546996 | chr16_56940859_+ | 2.74564641974103e-06 | 0.372125964658303 | 3.40488094671272e-06 | 0.368867296497411 | 0.150585009350966 | 0.117945374384575 |
| CER | ADediting_547001 | chr16_56940879_+ | 4.65861273231905e-05 | 0.32608117322836 | 0.000316894441153301 | 0.290104988096893 | 0.671143178561957 | 0.0349485446283684 |
| CER | ADediting_547002 | chr16_56940890_+ | 3.64233152360628e-05 | 0.330384348277222 | 3.30797039918807e-06 | 0.369306617103182 | 0.223027585447619 | 0.100078707970765 |
| DLPFC | ADediting_547003 | chr16_56940945_+ | 0.462272679661365 | 0.041902360411922 | 0.344585333906656 | -0.0538591808316844 | 8.40360985178875e-09 | 0.3198148383789 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 7.94834405663495e-39 | 0.651459036838821 | 1.95297021078017e-27 | 0.564051730705183 | 0.000707773781888823 | 0.191336015654085 |
| AC | 5.03476942737242e-45 | 0.74234335133567 | 4.71735509010892e-25 | 0.592180903368883 | 2.48963304411886e-20 | 0.540074367358434 |
| PCC | 4.78502312241604e-13 | 0.492179301174328 | 3.95690144356382e-14 | 0.5115434746398 | 0.00120820794913856 | 0.232524065981135 |
| CER | 6.75131060157915e-18 | 0.628993332021748 | 3.84900719567633e-22 | 0.685420783570839 | 3.56608085249298e-05 | 0.330751306812938 |
| TCX | 7.15692768229468e-15 | 0.580236386846069 | 0.000229163514988583 | 0.296522955493881 | 1.40926310142904e-08 | 0.442684087778184 |
| FP | 1.36476965776733e-14 | 0.5353900121709 | 1.77599398114273e-15 | 0.550248888753399 | 3.22865339656387e-05 | 0.306199034097156 |
| IFG | 1.92316123766535e-05 | 0.745175097233956 | 2.05126466660247e-05 | 0.743545254721595 | 0.0199636378816436 | 0.462350727485227 |
| PG | 8.23823169594973e-22 | 0.628164997743496 | 9.01978027633826e-19 | 0.589222285613217 | 0.160304709817386 | 0.103370606818774 |
| STG | 1.52908452582912e-14 | 0.717898452316602 | 3.63302533388189e-09 | 0.589538024542214 | 0.008002013290907 | 0.287526044003496 |
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Relation with AD stages for HERPUD1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| IFG | ADediting_546996 | chr16_56940859_+ | 0.0387176849807944 | 0.415790006692857 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 3.59026162288317e-05 | 0.386564459615572 |
| TCX | 6.89395063439467e-07 | 0.460288046547462 |
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RelatedDrugs for HERPUD1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for HERPUD1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| HERPUD1 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| HERPUD1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| HERPUD1 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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