ADeditome Logo

Home

Download

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for SAFB2

check button Gene summary
Gene informationGene symbol

SAFB2

Gene ID

9667

Gene namescaffold attachment factor B2
Synonyms-
Cytomap

19p13.3

Type of geneprotein-coding
Descriptionscaffold attachment factor B2
Modification date20200313
UniProtAcc

Q14151,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

Top

RNA A-to-I events for SAFB2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_783285(5591533, -), ADediting_783286(5591550, -), ADediting_783287(5594726, -), ADediting_783288(5594764, -), ADediting_783289(5594790, -), ADediting_783290(5594973, -), ADediting_783291(5594987, -), ADediting_783292(5595068, -), ADediting_783293(5595815, -), ADediting_783294(5595864, -), ADediting_783295(5596006, -), ADediting_783296(5596008, -), ADediting_783297(5596019, -), ADediting_783298(5596083, -), ADediting_783299(5596093, -), ADediting_783300(5596100, -), ADediting_783301(5596114, -), ADediting_783302(5596115, -), ADediting_783303(5596119, -), ADediting_783304(5596135, -), ADediting_783305(5596139, -), ADediting_783306(5596141, -), ADediting_783307(5596151, -), ADediting_783308(5596154, -), ADediting_783309(5596163, -), ADediting_783310(5596180, -), ADediting_783311(5596216, -), ADediting_783312(5596225, -), ADediting_783313(5596227, -), ADediting_783314(5596241, -), ADediting_783315(5596389, -), ADediting_783316(5596391, -), ADediting_783317(5596397, -), ADediting_783318(5596411, -), ADediting_783319(5596447, -), ADediting_783320(5596460, -), ADediting_783321(5596469, -), ADediting_783322(5596473, -), ADediting_783323(5596489, -), ADediting_783324(5596501, -), ADediting_783325(5596509, -), ADediting_783326(5596512, -), ADediting_783327(5596518, -), ADediting_783328(5596520, -), ADediting_783329(5596521, -), ADediting_783330(5596523, -), ADediting_783331(5596526, -), ADediting_783332(5596537, -), ADediting_783333(5596538, -), ADediting_783334(5596560, -), ADediting_783335(5596562, -), ADediting_783336(5596586, -), ADediting_783337(5596615, -), ADediting_783338(5596616, -), ADediting_783339(5596622, -), ADediting_783340(5604160, -), ADediting_783341(5604292, -), ADediting_783342(5604310, -), ADediting_783343(5605233, -), ADediting_783344(5605242, -), ADediting_783345(5605308, -), ADediting_783346(5605332, -), ADediting_783347(5605378, -), ADediting_783348(5607098, -), ADediting_783349(5607103, -), ADediting_783350(5608701, -), ADediting_783351(5608793, -), ADediting_783352(5608804, -), ADediting_783353(5608805, -), ADediting_783354(5608856, -), ADediting_783355(5608865, -), ADediting_783356(5608885, -), ADediting_783357(5608891, -), ADediting_783358(5608900, -), ADediting_783359(5608913, -), ADediting_783360(5608926, -), ADediting_783361(5608936, -), ADediting_783362(5608965, -), ADediting_783363(5608966, -), ADediting_783364(5609019, -), ADediting_783365(5609361, -), ADediting_783366(5609369, -), ADediting_783367(5609371, -), ADediting_783368(5609389, -), ADediting_783370(5609424, -), ADediting_783371(5609432, -), ADediting_783372(5609442, -), ADediting_783374(5609468, -), ADediting_783375(5609472, -), ADediting_783376(5609477, -), ADediting_783377(5609483, -), ADediting_783380(5609497, -), ADediting_783381(5609498, -), ADediting_783383(5609507, -), ADediting_783385(5609913, -), ADediting_783399(5614029, -), ADediting_783400(5614046, -), ADediting_783401(5614059, -), ADediting_783402(5614091, -), ADediting_783403(5614123, -), ADediting_783404(5614124, -), ADediting_783405(5614125, -), ADediting_783406(5614126, -), ADediting_783407(5614172, -), ADediting_783408(5614190, -), ADediting_783409(5614219, -), ADediting_783410(5614225, -), ADediting_783415(5614993, -), ADediting_783416(5615056, -), ADediting_783417(5615110, -), ADediting_783418(5615190, -), ADediting_783419(5615198, -), ADediting_783421(5615233, -), ADediting_783422(5615268, -), ADediting_783423(5615269, -), ADediting_783424(5615272, -), ADediting_783425(5615349, -), ADediting_783426(5616834, -), ADediting_783427(5616922, -), ADediting_783428(5619595, -), ADediting_783429(5619681, -), ADediting_783430(5619689, -), ADediting_783431(5619723, -), ADediting_783432(5619783, -), ADediting_783433(5619788, -), ADediting_1559160(5596071, -), ADediting_1559161(5596396, -), ADediting_1559162(5596406, -), ADediting_1559163(5596466, -), ADediting_1559164(5596477, -), ADediting_1559165(5596505, -), ADediting_1559166(5596522, -), ADediting_1559167(5596589, -), ADediting_1559168(5596624, -), ADediting_1559169(5597873, -), ADediting_1559170(5604223, -), ADediting_1559171(5604322, -), ADediting_1559172(5604323, -), ADediting_1559173(5604336, -), ADediting_1559174(5604378, -), ADediting_1559175(5605318, -), ADediting_1559176(5605372, -), ADediting_1559177(5606510, -), ADediting_1559178(5608880, -), ADediting_1559179(5609471, -), ADediting_1559180(5609929, -), ADediting_1631699(5608924, -),

Top

RNA editing positional annotations for SAFB2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_783285chr19_5591533_-intronic
ADediting_783286chr19_5591550_-intronic
ADediting_783287chr19_5594726_-intronic
ADediting_783288chr19_5594764_-intronic
ADediting_783289chr19_5594790_-intronic
ADediting_783290chr19_5594973_-intronic
ADediting_783291chr19_5594987_-intronic
ADediting_783292chr19_5595068_-intronic
ADediting_783293chr19_5595815_-intronic
ADediting_783294chr19_5595864_-intronic
ADediting_783295chr19_5596006_-intronic
ADediting_783296chr19_5596008_-intronic
ADediting_783297chr19_5596019_-intronic
ADediting_783298chr19_5596083_-intronic
ADediting_783299chr19_5596093_-intronic
ADediting_783300chr19_5596100_-intronic
ADediting_783301chr19_5596114_-intronic
ADediting_783302chr19_5596115_-intronic
ADediting_783303chr19_5596119_-intronic
ADediting_783304chr19_5596135_-intronic
ADediting_783305chr19_5596139_-intronic
ADediting_783306chr19_5596141_-intronic
ADediting_783307chr19_5596151_-intronic
ADediting_783308chr19_5596154_-intronic
ADediting_783309chr19_5596163_-intronic
ADediting_783310chr19_5596180_-intronic
ADediting_783311chr19_5596216_-intronic
ADediting_783312chr19_5596225_-intronic
ADediting_783313chr19_5596227_-intronic
ADediting_783314chr19_5596241_-intronic
ADediting_783315chr19_5596389_-intronic
ADediting_783316chr19_5596391_-intronic
ADediting_783317chr19_5596397_-intronic
ADediting_783318chr19_5596411_-intronic
ADediting_783319chr19_5596447_-intronic
ADediting_783320chr19_5596460_-intronic
ADediting_783321chr19_5596469_-intronic
ADediting_783322chr19_5596473_-intronic
ADediting_783323chr19_5596489_-intronic
ADediting_783324chr19_5596501_-intronic
ADediting_783325chr19_5596509_-intronic
ADediting_783326chr19_5596512_-intronic
ADediting_783327chr19_5596518_-intronic
ADediting_783328chr19_5596520_-intronic
ADediting_783329chr19_5596521_-intronic
ADediting_783330chr19_5596523_-intronic
ADediting_783331chr19_5596526_-intronic
ADediting_783332chr19_5596537_-intronic
ADediting_783333chr19_5596538_-intronic
ADediting_783334chr19_5596560_-intronic
ADediting_783335chr19_5596562_-intronic
ADediting_783336chr19_5596586_-intronic
ADediting_783337chr19_5596615_-intronic
ADediting_783338chr19_5596616_-intronic
ADediting_783339chr19_5596622_-intronic
ADediting_783340chr19_5604160_-intronic
ADediting_783341chr19_5604292_-intronic
ADediting_783342chr19_5604310_-intronic
ADediting_783343chr19_5605233_-intronic
ADediting_783344chr19_5605242_-intronic
ADediting_783345chr19_5605308_-intronic
ADediting_783346chr19_5605332_-intronic
ADediting_783347chr19_5605378_-intronic
ADediting_783348chr19_5607098_-intronic
ADediting_783349chr19_5607103_-intronic
ADediting_783350chr19_5608701_-intronic
ADediting_783351chr19_5608793_-intronic
ADediting_783352chr19_5608804_-intronic
ADediting_783353chr19_5608805_-intronic
ADediting_783354chr19_5608856_-intronic
ADediting_783355chr19_5608865_-intronic
ADediting_783356chr19_5608885_-intronic
ADediting_783357chr19_5608891_-intronic
ADediting_783358chr19_5608900_-intronic
ADediting_783359chr19_5608913_-intronic
ADediting_783360chr19_5608926_-intronic
ADediting_783361chr19_5608936_-intronic
ADediting_783362chr19_5608965_-intronic
ADediting_783363chr19_5608966_-intronic
ADediting_783364chr19_5609019_-intronic
ADediting_783365chr19_5609361_-intronic
ADediting_783366chr19_5609369_-intronic
ADediting_783367chr19_5609371_-intronic
ADediting_783368chr19_5609389_-intronic
ADediting_783370chr19_5609424_-intronic
ADediting_783371chr19_5609432_-intronic
ADediting_783372chr19_5609442_-intronic
ADediting_783374chr19_5609468_-intronic
ADediting_783375chr19_5609472_-intronic
ADediting_783376chr19_5609477_-intronic
ADediting_783377chr19_5609483_-intronic
ADediting_783380chr19_5609497_-intronic
ADediting_783381chr19_5609498_-intronic
ADediting_783383chr19_5609507_-intronic
ADediting_783385chr19_5609913_-intronic
ADediting_783399chr19_5614029_-intronic
ADediting_783400chr19_5614046_-intronic
ADediting_783401chr19_5614059_-intronic
ADediting_783402chr19_5614091_-intronic
ADediting_783403chr19_5614123_-intronic
ADediting_783404chr19_5614124_-intronic
ADediting_783405chr19_5614125_-intronic
ADediting_783406chr19_5614126_-intronic
ADediting_783407chr19_5614172_-intronic
ADediting_783408chr19_5614190_-intronic
ADediting_783409chr19_5614219_-intronic
ADediting_783410chr19_5614225_-intronic
ADediting_783415chr19_5614993_-intronic
ADediting_783416chr19_5615056_-intronic
ADediting_783417chr19_5615110_-intronic
ADediting_783418chr19_5615190_-intronic
ADediting_783419chr19_5615198_-intronic
ADediting_783421chr19_5615233_-intronic
ADediting_783422chr19_5615268_-intronic
ADediting_783423chr19_5615269_-intronic
ADediting_783424chr19_5615272_-intronic
ADediting_783425chr19_5615349_-intronic
ADediting_783426chr19_5616834_-intronic
ADediting_783427chr19_5616922_-intronic
ADediting_783428chr19_5619595_-intronic
ADediting_783429chr19_5619681_-intronic
ADediting_783430chr19_5619689_-intronic
ADediting_783431chr19_5619723_-intronic
ADediting_783432chr19_5619783_-intronic
ADediting_783433chr19_5619788_-intronic
ADediting_1559160chr19_5596071_-intronic
ADediting_1559161chr19_5596396_-intronic
ADediting_1559162chr19_5596406_-intronic
ADediting_1559163chr19_5596466_-intronic
ADediting_1559164chr19_5596477_-intronic
ADediting_1559165chr19_5596505_-intronic
ADediting_1559166chr19_5596522_-intronic
ADediting_1559167chr19_5596589_-intronic
ADediting_1559168chr19_5596624_-intronic
ADediting_1559169chr19_5597873_-intronic
ADediting_1559170chr19_5604223_-intronic
ADediting_1559171chr19_5604322_-intronic
ADediting_1559172chr19_5604323_-intronic
ADediting_1559173chr19_5604336_-intronic
ADediting_1559174chr19_5604378_-intronic
ADediting_1559175chr19_5605318_-intronic
ADediting_1559176chr19_5605372_-intronic
ADediting_1559177chr19_5606510_-intronic
ADediting_1559178chr19_5608880_-intronic
ADediting_1559179chr19_5609471_-intronic
ADediting_1559180chr19_5609929_-intronic
ADediting_1631699chr19_5608924_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_783285chr19_5591533_-SINEAluName=AluSx3
ADediting_783286chr19_5591550_-SINEAluName=AluSx3
ADediting_783288chr19_5594764_-SINEAluName=AluJo
ADediting_783289chr19_5594790_-SINEAluName=AluJo
ADediting_783290chr19_5594973_-SINEAluName=AluJr
ADediting_783291chr19_5594987_-SINEAluName=AluJr
ADediting_783292chr19_5595068_-SINEAluName=AluJr
ADediting_783295chr19_5596006_-SINEAluName=AluSg
ADediting_783296chr19_5596008_-SINEAluName=AluSg
ADediting_783297chr19_5596019_-SINEAluName=AluSg
ADediting_783298chr19_5596083_-SINEAluName=AluSg
ADediting_783299chr19_5596093_-SINEAluName=AluSg
ADediting_783300chr19_5596100_-SINEAluName=AluSg
ADediting_783301chr19_5596114_-SINEAluName=AluSg
ADediting_783302chr19_5596115_-SINEAluName=AluSg
ADediting_783303chr19_5596119_-SINEAluName=AluSg
ADediting_783304chr19_5596135_-SINEAluName=AluSg
ADediting_783305chr19_5596139_-SINEAluName=AluSg
ADediting_783306chr19_5596141_-SINEAluName=AluSg
ADediting_783307chr19_5596151_-SINEAluName=AluSg
ADediting_783308chr19_5596154_-SINEAluName=AluSg
ADediting_783309chr19_5596163_-SINEAluName=AluSg
ADediting_783310chr19_5596180_-SINEAluName=AluSg
ADediting_783311chr19_5596216_-SINEAluName=AluSg
ADediting_783312chr19_5596225_-SINEAluName=AluSg
ADediting_783313chr19_5596227_-SINEAluName=AluSg
ADediting_783314chr19_5596241_-SINEAluName=AluSg
ADediting_783315chr19_5596389_-SINEAluName=AluJb
ADediting_783316chr19_5596391_-SINEAluName=AluJb
ADediting_783317chr19_5596397_-SINEAluName=AluJb
ADediting_783318chr19_5596411_-SINEAluName=AluJb
ADediting_783319chr19_5596447_-SINEAluName=AluJb
ADediting_783320chr19_5596460_-SINEAluName=AluJb
ADediting_783321chr19_5596469_-SINEAluName=AluJb
ADediting_783322chr19_5596473_-SINEAluName=AluJb
ADediting_783323chr19_5596489_-SINEAluName=AluJb
ADediting_783324chr19_5596501_-SINEAluName=AluJb
ADediting_783325chr19_5596509_-SINEAluName=AluJb
ADediting_783326chr19_5596512_-SINEAluName=AluJb
ADediting_783327chr19_5596518_-SINEAluName=AluJb
ADediting_783328chr19_5596520_-SINEAluName=AluJb
ADediting_783329chr19_5596521_-SINEAluName=AluJb
ADediting_783330chr19_5596523_-SINEAluName=AluJb
ADediting_783331chr19_5596526_-SINEAluName=AluJb
ADediting_783332chr19_5596537_-SINEAluName=AluJb
ADediting_783333chr19_5596538_-SINEAluName=AluJb
ADediting_783334chr19_5596560_-SINEAluName=AluJb
ADediting_783335chr19_5596562_-SINEAluName=AluJb
ADediting_783336chr19_5596586_-SINEAluName=AluJb
ADediting_783337chr19_5596615_-SINEAluName=AluJb
ADediting_783338chr19_5596616_-SINEAluName=AluJb
ADediting_783339chr19_5596622_-SINEAluName=AluJb
ADediting_783340chr19_5604160_-SINEAluName=AluJb
ADediting_783341chr19_5604292_-SINEAluName=AluJb
ADediting_783342chr19_5604310_-SINEAluName=AluJb
ADediting_783343chr19_5605233_-SINEAluName=AluSx1
ADediting_783344chr19_5605242_-SINEAluName=AluSx1
ADediting_783345chr19_5605308_-SINEAluName=AluSx1
ADediting_783346chr19_5605332_-SINEAluName=AluSx1
ADediting_783347chr19_5605378_-SINEAluName=AluSx1
ADediting_783348chr19_5607098_-SINEAluName=AluY
ADediting_783349chr19_5607103_-SINEAluName=AluY
ADediting_783351chr19_5608793_-SINEAluName=AluSx1
ADediting_783352chr19_5608804_-SINEAluName=AluSx1
ADediting_783353chr19_5608805_-SINEAluName=AluSx1
ADediting_783354chr19_5608856_-SINEAluName=AluSx1
ADediting_783355chr19_5608865_-SINEAluName=AluSx1
ADediting_783356chr19_5608885_-SINEAluName=AluSx1
ADediting_783357chr19_5608891_-SINEAluName=AluSx1
ADediting_783358chr19_5608900_-SINEAluName=AluSx1
ADediting_783359chr19_5608913_-SINEAluName=AluSx1
ADediting_783360chr19_5608926_-SINEAluName=AluSx1
ADediting_783361chr19_5608936_-SINEAluName=AluSx1
ADediting_783362chr19_5608965_-SINEAluName=AluSx1
ADediting_783363chr19_5608966_-SINEAluName=AluSx1
ADediting_783364chr19_5609019_-SINEAluName=AluSx1
ADediting_783365chr19_5609361_-SINEAluName=AluSx
ADediting_783366chr19_5609369_-SINEAluName=AluSx
ADediting_783367chr19_5609371_-SINEAluName=AluSx
ADediting_783368chr19_5609389_-SINEAluName=AluSx
ADediting_783370chr19_5609424_-SINEAluName=AluSx
ADediting_783371chr19_5609432_-SINEAluName=AluSx
ADediting_783372chr19_5609442_-SINEAluName=AluSx
ADediting_783374chr19_5609468_-SINEAluName=AluSx
ADediting_783375chr19_5609472_-SINEAluName=AluSx
ADediting_783376chr19_5609477_-SINEAluName=AluSx
ADediting_783377chr19_5609483_-SINEAluName=AluSx
ADediting_783380chr19_5609497_-SINEAluName=AluSx
ADediting_783381chr19_5609498_-SINEAluName=AluSx
ADediting_783383chr19_5609507_-SINEAluName=AluSx
ADediting_783385chr19_5609913_-SINEAluName=AluJo
ADediting_783399chr19_5614029_-SINEAluName=AluSq2
ADediting_783400chr19_5614046_-SINEAluName=AluSq2
ADediting_783401chr19_5614059_-SINEAluName=AluSq2
ADediting_783402chr19_5614091_-SINEAluName=AluSq2
ADediting_783403chr19_5614123_-SINEAluName=AluSq2
ADediting_783404chr19_5614124_-SINEAluName=AluSq2
ADediting_783405chr19_5614125_-SINEAluName=AluSq2
ADediting_783406chr19_5614126_-SINEAluName=AluSq2
ADediting_783407chr19_5614172_-SINEAluName=AluSq2
ADediting_783408chr19_5614190_-SINEAluName=AluSq2
ADediting_783409chr19_5614219_-SINEAluName=AluSq2
ADediting_783410chr19_5614225_-SINEAluName=AluSq2
ADediting_783415chr19_5614993_-SINEAluName=AluSz
ADediting_783416chr19_5615056_-SINEAluName=AluSz
ADediting_783417chr19_5615110_-SINEAluName=AluSx3
ADediting_783418chr19_5615190_-SINEAluName=AluSx3
ADediting_783419chr19_5615198_-SINEAluName=AluSx3
ADediting_783421chr19_5615233_-SINEAluName=AluSx3
ADediting_783422chr19_5615268_-SINEAluName=AluSx3
ADediting_783423chr19_5615269_-SINEAluName=AluSx3
ADediting_783424chr19_5615272_-SINEAluName=AluSx3
ADediting_783425chr19_5615349_-SINEAluName=AluSx3
ADediting_783426chr19_5616834_-SINEAluName=AluSx4
ADediting_783427chr19_5616922_-SINEAluName=AluSx4
ADediting_783428chr19_5619595_-SINEAluName=AluSq
ADediting_783429chr19_5619681_-SINEAluName=AluSq
ADediting_783430chr19_5619689_-SINEAluName=AluSq
ADediting_783431chr19_5619723_-SINEAluName=AluSq
ADediting_783432chr19_5619783_-SINEAluName=AluSq
ADediting_783433chr19_5619788_-SINEAluName=AluSq
ADediting_1559160chr19_5596071_-SINEAluName=AluSg
ADediting_1559161chr19_5596396_-SINEAluName=AluJb
ADediting_1559162chr19_5596406_-SINEAluName=AluJb
ADediting_1559163chr19_5596466_-SINEAluName=AluJb
ADediting_1559164chr19_5596477_-SINEAluName=AluJb
ADediting_1559165chr19_5596505_-SINEAluName=AluJb
ADediting_1559166chr19_5596522_-SINEAluName=AluJb
ADediting_1559167chr19_5596589_-SINEAluName=AluJb
ADediting_1559168chr19_5596624_-SINEAluName=AluJb
ADediting_1559169chr19_5597873_-SINEAluName=AluSz
ADediting_1559170chr19_5604223_-SINEAluName=AluJb
ADediting_1559171chr19_5604322_-SINEAluName=AluJb
ADediting_1559172chr19_5604323_-SINEAluName=AluJb
ADediting_1559173chr19_5604336_-SINEAluName=AluJb
ADediting_1559174chr19_5604378_-SINEAluName=AluJb
ADediting_1559175chr19_5605318_-SINEAluName=AluSx1
ADediting_1559176chr19_5605372_-SINEAluName=AluSx1
ADediting_1559177chr19_5606510_-SINEAluName=AluJr
ADediting_1559178chr19_5608880_-SINEAluName=AluSx1
ADediting_1559179chr19_5609471_-SINEAluName=AluSx
ADediting_1559180chr19_5609929_-SINEAluName=AluJo
ADediting_1631699chr19_5608924_-SINEAluName=AluSx1

Top

RNA A-to-I editing events in the alternative splicing sites for SAFB2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_783356chr19_5608885_-5608878:56089003ss5iAATTTTTGTATTTTCAGTAGAGA2.95AATTTTTGTATTTTCGGTAGAGA4.28
ESADediting_783356chr19_5608885_-5608881:56089033ss2iGCTAATTTTTGTATTTTCAGTAG4.27GCTAATTTTTGTATTTTCGGTAG-3.68
ESADediting_783357chr19_5608891_-5608878:56089003ss11iAATTTTTGTATTTTCAGTAGAGA2.95AATTTTTGTGTTTTCAGTAGAGA4.51
ESADediting_783357chr19_5608891_-5608881:56089033ss8iGCTAATTTTTGTATTTTCAGTAG4.27GCTAATTTTTGTGTTTTCAGTAG4.98
ESADediting_783358chr19_5608900_-5608878:56089003ss20iAATTTTTGTATTTTCAGTAGAGA2.95GATTTTTGTATTTTCAGTAGAGA3.16
ESADediting_783358chr19_5608900_-5608881:56089033ss17iGCTAATTTTTGTATTTTCAGTAG4.27GCTGATTTTTGTATTTTCAGTAG4.70

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for SAFB2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot
boxplot
boxplot
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

Top

Protein coding region RNA A-to-I editings for SAFB2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


Top

The effects of the RNA editing to the miRNA binding sites for SAFB2


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337758chr7_5495892_-ENSG00000130254.12ENST00000252542.9SAFB2-201hsa-miR-589-5pchr19558717955871857mer-m855871785587199153-21.32

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000130254.12ENST00000252542.9SAFB2-201hsa-miR-589-3pchr19558706755870737mer-m855870665587089150-13.06

check button Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for SAFB2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

Top

Relation with ADAR for SAFB2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1559173chr19_5604336_-0.04320955955881160.1653147530283499.92142188343241e-060.3521215229709180.007899145840158380.216128472495593
DLPFCADediting_783289chr19_5594790_-6.57876909418438e-070.278005649172322.1399963105292e-090.3316934733287940.8338964608195610.0119584333126669
CERADediting_783297chr19_5596019_-8.07556573402837e-060.3554190505627174.46426938833701e-050.326830916577450.04430701012167620.164467591048163
CERADediting_783313chr19_5596227_-0.0004538256602004890.2828127411458726.89676590741046e-060.3579219965051790.0176026790097190.193607773205461
CERADediting_783316chr19_5596391_-0.000417821546995730.2845085592639250.0001172995394953250.3093291188732690.4049682987471050.0684893311290105
CERADediting_783322chr19_5596473_-0.0004681283374056430.2821733831450836.65304431296435e-050.319733047027520.8701612729762910.0134579112141583
CERADediting_783327chr19_5596518_-0.0001263023827275080.3079436379423763.39015944792519e-050.3316268897333730.3538783354789980.0762242657495748
TCXADediting_783327chr19_5596518_-0.4763222382260660.05859352514936040.365102313539188-0.0744691388633214.51850271472949e-050.32661865883552
CERADediting_783331chr19_5596526_-9.84393801913765e-050.31258626841110.001419754087527710.2582387421117780.1638980069850860.114246107708529
TCXADediting_783331chr19_5596526_-0.08419359511031360.1414706034217820.581349957981622-0.04537917224065224.63008656549698e-050.3261893627531
CERADediting_783332chr19_5596537_-0.0001746067971359510.3017936101068874.49167583477793e-060.3646194994334740.04080251236904270.167237815519414
CERADediting_783340chr19_5604160_-0.07337005216624880.1466308851347112.1633843158269e-060.375694343308090.001523570378207810.256639650365742
DLPFCADediting_783354chr19_5608856_-0.1565733717564720.08065731313236530.268529766189479-0.06303453474327651.60823782400454e-120.387069688687326
DLPFCADediting_783361chr19_5608936_-0.400905202703459-0.04787515744318820.0114525475721588-0.1434496122892884.17581903708693e-130.396370565510741
DLPFCADediting_783362chr19_5608965_-0.288479300668042-0.06047618960599740.00596207929686312-0.1558556357865817.62463505547997e-120.375957123875773
DLPFCADediting_783363chr19_5608966_-0.671246804660897-0.02420066169955270.044266548840502-0.1143357878681341.99868856628625e-120.385542682412062
DLPFCADediting_783367chr19_5609371_-0.8247912306321620.01262442666518310.130722878490096-0.08602198711750251.24620112194024e-160.446970915803738
DLPFCADediting_783368chr19_5609389_-0.492333865918549-0.03913951523836740.0269887220675536-0.1256244920325066.74618240592535e-130.393095384728902
DLPFCADediting_783370chr19_5609424_-0.755139970451686-0.01778341715577270.0429453012794009-0.1150519353950282.11834726294224e-160.443910122171354
DLPFCADediting_783371chr19_5609432_-0.8810727092626290.008531559650733680.0815659825637072-0.09907700715621173.16872171819766e-240.533741537541907
DLPFCADediting_783377chr19_5609483_-0.203172442730864-0.07247453427624450.00361705365649958-0.1647976641986511.67020959209252e-120.386804622224659
CERADediting_783385chr19_5609913_-0.002135940711715090.2488431007230658.80211499302525e-050.3146453438301420.05134154922017610.159418229425597

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.29137425116636e-120.3886033262924361.22770574618385e-140.4194066257886457.71859721210427e-300.58486528496196
AC2.73121035462421e-230.5737946243330368.03008993033789e-170.4944873263476319.75902324853014e-240.578567876980439
PCC4.65212458887798e-100.4313962018606691.66643918633951e-110.4623081770639499.23932743472697e-110.446792810638974
CER0.001405011147293720.2584744248110751.4658326686634e-110.5155647912470340.0003033249881690640.290980368246172
TCX0.005879673207932350.2239075772927260.005659009846022880.2248971515810581.34557286429334e-050.347171685576026
FP8.87872774505714e-070.3585940715340770.5634914931194580.04358417143963467.09170984659083e-090.416902624712863
IFG0.0001408509106690290.6887279647046218.36294273975305e-060.7651892431662880.004714830216262260.546393835117279
PG2.17567464538763e-210.6230726390010011.74700464083129e-140.5235862961101920.0003166686867864130.261219073252705
STG0.01443746439942280.2660583175980070.6973034082817380.04306493971801289.88608410058139e-060.461614367001864

Top

Relation with AD stages for SAFB2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_783313chr19_5596227_-6.96399239076428e-050.373158264671819
IFGADediting_783327chr19_5596518_-0.01130599370490140.497952103823781
IFGADediting_783331chr19_5596526_-0.03547133699799280.422303326441651

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER6.80211534181372e-060.417872603457102
TCX0.0003158258061816260.343232338975088

Top

RelatedDrugs for SAFB2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for SAFB2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource