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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ENTPD4 |
 Gene summary |
| Gene information | Gene symbol | ENTPD4 | Gene ID | 9583 |
| Gene name | ectonucleoside triphosphate diphosphohydrolase 4 | |
| Synonyms | LALP70|LAP70|LYSAL1|NTPDase-4|UDPase | |
| Cytomap | 8p21.3 | |
| Type of gene | protein-coding | |
| Description | ectonucleoside triphosphate diphosphohydrolase 4golgi luminal UDPaseguanosine-diphosphatase like proteinlysosomal apyrase-like 1lysosomal apyrase-like protein of 70 kDauridine-diphosphatase | |
| Modification date | 20200313 | |
| UniProtAcc | Q9Y227, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| ENTPD4 | GO:0006256 | UDP catabolic process | 9556635 |
Top |
RNA A-to-I events for ENTPD4 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1397404(23386200, -), ADediting_1397405(23386204, -), ADediting_1397406(23386269, -), ADediting_1397407(23386271, -), ADediting_1397408(23386349, -), ADediting_1397409(23386355, -), ADediting_1397410(23406430, -), ADediting_1397411(23406467, -), ADediting_1397412(23406472, -), ADediting_1397413(23406473, -), ADediting_1397414(23406483, -), ADediting_1397415(23406499, -), ADediting_1397416(23406517, -), ADediting_1397417(23406553, -), ADediting_1397418(23406554, -), ADediting_1397419(23406572, -), ADediting_1397420(23408858, -), ADediting_1397421(23409926, -), ADediting_1397422(23409928, -), ADediting_1397423(23409929, -), ADediting_1397424(23410014, -), ADediting_1397425(23410018, -), ADediting_1397426(23412942, -), ADediting_1397427(23412955, -), ADediting_1397428(23413931, -), ADediting_1397429(23414040, -), ADediting_1397430(23414048, -), ADediting_1397431(23414049, -), ADediting_1397432(23414102, -), ADediting_1397433(23414109, -), ADediting_1397434(23414119, -), ADediting_1397435(23414128, -), ADediting_1397436(23414145, -), ADediting_1397437(23414149, -), ADediting_1397438(23414154, -), ADediting_1397439(23414164, -), ADediting_1397440(23414173, -), ADediting_1397441(23414187, -), ADediting_1397442(23414192, -), ADediting_1397443(23414194, -), ADediting_1397444(23414210, -), ADediting_1397445(23414211, -), ADediting_1397446(23414212, -), ADediting_1397447(23414218, -), ADediting_1397448(23414220, -), ADediting_1397449(23414221, -), ADediting_1397450(23414235, -), ADediting_1397451(23414236, -), ADediting_1397452(23414244, -), ADediting_1397453(23414291, -), ADediting_1397454(23414653, -), ADediting_1397455(23414675, -), ADediting_1397456(23414730, -), ADediting_1397457(23414766, -), ADediting_1397458(23415178, -), ADediting_1397459(23415183, -), ADediting_1397460(23415285, -), ADediting_1397461(23418627, -), ADediting_1397462(23418636, -), ADediting_1397463(23418639, -), ADediting_1397464(23418717, -), ADediting_1397465(23418762, -), ADediting_1397466(23418776, -), ADediting_1397467(23418821, -), ADediting_1397468(23419905, -), ADediting_1397469(23420065, -), ADediting_1397470(23423183, -), ADediting_1397471(23423380, -), ADediting_1397472(23426167, -), ADediting_1397473(23426299, -), ADediting_1397474(23426308, -), ADediting_1397475(23426369, -), ADediting_1397476(23426869, -), ADediting_1397477(23426875, -), ADediting_1397478(23426881, -), ADediting_1397479(23426900, -), ADediting_1397480(23432559, -), ADediting_1397481(23432561, -), ADediting_1397482(23432566, -), ADediting_1397483(23432584, -), ADediting_1397484(23432599, -), ADediting_1397485(23432610, -), ADediting_1397486(23432637, -), ADediting_1397487(23432663, -), ADediting_1397488(23432669, -), ADediting_1397489(23432673, -), ADediting_1397490(23432727, -), ADediting_1397491(23432762, -), ADediting_1397492(23432765, -), ADediting_1397493(23432770, -), ADediting_1397494(23432779, -), ADediting_1590244(23412742, -), ADediting_1590245(23426073, -), ADediting_1590246(23426085, -), ADediting_1590247(23426110, -), ADediting_1590248(23426313, -), ADediting_1590249(23426314, -), ADediting_1590250(23426330, -), ADediting_1590251(23426882, -), ADediting_1590252(23432713, -), |
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RNA editing positional annotations for ENTPD4 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1397404 | chr8_23386200_- | intronic |
| ADediting_1397405 | chr8_23386204_- | intronic |
| ADediting_1397406 | chr8_23386269_- | intronic |
| ADediting_1397407 | chr8_23386271_- | intronic |
| ADediting_1397408 | chr8_23386349_- | intronic |
| ADediting_1397409 | chr8_23386355_- | intronic |
| ADediting_1397410 | chr8_23406430_- | intronic |
| ADediting_1397411 | chr8_23406467_- | intronic |
| ADediting_1397412 | chr8_23406472_- | intronic |
| ADediting_1397413 | chr8_23406473_- | intronic |
| ADediting_1397414 | chr8_23406483_- | intronic |
| ADediting_1397415 | chr8_23406499_- | intronic |
| ADediting_1397416 | chr8_23406517_- | intronic |
| ADediting_1397417 | chr8_23406553_- | intronic |
| ADediting_1397418 | chr8_23406554_- | intronic |
| ADediting_1397419 | chr8_23406572_- | intronic |
| ADediting_1397420 | chr8_23408858_- | intronic |
| ADediting_1397421 | chr8_23409926_- | intronic |
| ADediting_1397422 | chr8_23409928_- | intronic |
| ADediting_1397423 | chr8_23409929_- | intronic |
| ADediting_1397424 | chr8_23410014_- | intronic |
| ADediting_1397425 | chr8_23410018_- | intronic |
| ADediting_1397426 | chr8_23412942_- | intronic |
| ADediting_1397427 | chr8_23412955_- | intronic |
| ADediting_1397428 | chr8_23413931_- | intronic |
| ADediting_1397429 | chr8_23414040_- | intronic |
| ADediting_1397430 | chr8_23414048_- | intronic |
| ADediting_1397431 | chr8_23414049_- | intronic |
| ADediting_1397432 | chr8_23414102_- | intronic |
| ADediting_1397433 | chr8_23414109_- | intronic |
| ADediting_1397434 | chr8_23414119_- | intronic |
| ADediting_1397435 | chr8_23414128_- | intronic |
| ADediting_1397436 | chr8_23414145_- | intronic |
| ADediting_1397437 | chr8_23414149_- | intronic |
| ADediting_1397438 | chr8_23414154_- | intronic |
| ADediting_1397439 | chr8_23414164_- | intronic |
| ADediting_1397440 | chr8_23414173_- | intronic |
| ADediting_1397441 | chr8_23414187_- | intronic |
| ADediting_1397442 | chr8_23414192_- | intronic |
| ADediting_1397443 | chr8_23414194_- | intronic |
| ADediting_1397444 | chr8_23414210_- | intronic |
| ADediting_1397445 | chr8_23414211_- | intronic |
| ADediting_1397446 | chr8_23414212_- | intronic |
| ADediting_1397447 | chr8_23414218_- | intronic |
| ADediting_1397448 | chr8_23414220_- | intronic |
| ADediting_1397449 | chr8_23414221_- | intronic |
| ADediting_1397450 | chr8_23414235_- | intronic |
| ADediting_1397451 | chr8_23414236_- | intronic |
| ADediting_1397452 | chr8_23414244_- | intronic |
| ADediting_1397453 | chr8_23414291_- | intronic |
| ADediting_1397454 | chr8_23414653_- | intronic |
| ADediting_1397455 | chr8_23414675_- | intronic |
| ADediting_1397456 | chr8_23414730_- | intronic |
| ADediting_1397457 | chr8_23414766_- | intronic |
| ADediting_1397458 | chr8_23415178_- | intronic |
| ADediting_1397459 | chr8_23415183_- | intronic |
| ADediting_1397460 | chr8_23415285_- | intronic |
| ADediting_1397461 | chr8_23418627_- | intronic |
| ADediting_1397462 | chr8_23418636_- | intronic |
| ADediting_1397463 | chr8_23418639_- | intronic |
| ADediting_1397464 | chr8_23418717_- | intronic |
| ADediting_1397465 | chr8_23418762_- | intronic |
| ADediting_1397466 | chr8_23418776_- | intronic |
| ADediting_1397467 | chr8_23418821_- | intronic |
| ADediting_1397468 | chr8_23419905_- | intronic |
| ADediting_1397469 | chr8_23420065_- | intronic |
| ADediting_1397470 | chr8_23423183_- | intronic |
| ADediting_1397471 | chr8_23423380_- | intronic |
| ADediting_1397472 | chr8_23426167_- | intronic |
| ADediting_1397473 | chr8_23426299_- | intronic |
| ADediting_1397474 | chr8_23426308_- | intronic |
| ADediting_1397475 | chr8_23426369_- | intronic |
| ADediting_1397476 | chr8_23426869_- | intronic |
| ADediting_1397477 | chr8_23426875_- | intronic |
| ADediting_1397478 | chr8_23426881_- | intronic |
| ADediting_1397479 | chr8_23426900_- | intronic |
| ADediting_1397480 | chr8_23432559_- | UTR3 |
| ADediting_1397481 | chr8_23432561_- | UTR3 |
| ADediting_1397482 | chr8_23432566_- | UTR3 |
| ADediting_1397483 | chr8_23432584_- | UTR3 |
| ADediting_1397484 | chr8_23432599_- | UTR3 |
| ADediting_1397485 | chr8_23432610_- | UTR3 |
| ADediting_1397486 | chr8_23432637_- | UTR3 |
| ADediting_1397487 | chr8_23432663_- | UTR3 |
| ADediting_1397488 | chr8_23432669_- | UTR3 |
| ADediting_1397489 | chr8_23432673_- | UTR3 |
| ADediting_1397490 | chr8_23432727_- | UTR3 |
| ADediting_1397491 | chr8_23432762_- | UTR3 |
| ADediting_1397492 | chr8_23432765_- | UTR3 |
| ADediting_1397493 | chr8_23432770_- | UTR3 |
| ADediting_1397494 | chr8_23432779_- | UTR3 |
| ADediting_1590244 | chr8_23412742_- | intronic |
| ADediting_1590245 | chr8_23426073_- | intronic |
| ADediting_1590246 | chr8_23426085_- | intronic |
| ADediting_1590247 | chr8_23426110_- | intronic |
| ADediting_1590248 | chr8_23426313_- | intronic |
| ADediting_1590249 | chr8_23426314_- | intronic |
| ADediting_1590250 | chr8_23426330_- | intronic |
| ADediting_1590251 | chr8_23426882_- | intronic |
| ADediting_1590252 | chr8_23432713_- | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1397404 | chr8_23386200_- | SINE | Alu | Name=AluSx |
| ADediting_1397405 | chr8_23386204_- | SINE | Alu | Name=AluSx |
| ADediting_1397406 | chr8_23386269_- | SINE | Alu | Name=AluSx |
| ADediting_1397407 | chr8_23386271_- | SINE | Alu | Name=AluSx |
| ADediting_1397408 | chr8_23386349_- | SINE | Alu | Name=AluSx |
| ADediting_1397409 | chr8_23386355_- | SINE | Alu | Name=AluSx |
| ADediting_1397410 | chr8_23406430_- | SINE | Alu | Name=AluSz |
| ADediting_1397411 | chr8_23406467_- | SINE | Alu | Name=AluSz |
| ADediting_1397412 | chr8_23406472_- | SINE | Alu | Name=AluSz |
| ADediting_1397413 | chr8_23406473_- | SINE | Alu | Name=AluSz |
| ADediting_1397414 | chr8_23406483_- | SINE | Alu | Name=AluSz |
| ADediting_1397415 | chr8_23406499_- | SINE | Alu | Name=AluSz |
| ADediting_1397416 | chr8_23406517_- | SINE | Alu | Name=AluSz |
| ADediting_1397417 | chr8_23406553_- | SINE | Alu | Name=AluSz |
| ADediting_1397418 | chr8_23406554_- | SINE | Alu | Name=AluSz |
| ADediting_1397419 | chr8_23406572_- | SINE | Alu | Name=AluSz |
| ADediting_1397420 | chr8_23408858_- | SINE | Alu | Name=AluSx1 |
| ADediting_1397421 | chr8_23409926_- | SINE | Alu | Name=AluY |
| ADediting_1397422 | chr8_23409928_- | SINE | Alu | Name=AluY |
| ADediting_1397423 | chr8_23409929_- | SINE | Alu | Name=AluY |
| ADediting_1397424 | chr8_23410014_- | SINE | Alu | Name=AluY |
| ADediting_1397425 | chr8_23410018_- | SINE | Alu | Name=AluY |
| ADediting_1397426 | chr8_23412942_- | SINE | Alu | Name=AluY |
| ADediting_1397427 | chr8_23412955_- | SINE | Alu | Name=AluY |
| ADediting_1397428 | chr8_23413931_- | SINE | Alu | Name=FLAM_C |
| ADediting_1397429 | chr8_23414040_- | SINE | Alu | Name=AluSz |
| ADediting_1397430 | chr8_23414048_- | SINE | Alu | Name=AluSz |
| ADediting_1397431 | chr8_23414049_- | SINE | Alu | Name=AluSz |
| ADediting_1397432 | chr8_23414102_- | SINE | Alu | Name=AluSz |
| ADediting_1397433 | chr8_23414109_- | SINE | Alu | Name=AluSz |
| ADediting_1397434 | chr8_23414119_- | SINE | Alu | Name=AluSz |
| ADediting_1397435 | chr8_23414128_- | SINE | Alu | Name=AluSz |
| ADediting_1397436 | chr8_23414145_- | SINE | Alu | Name=AluSz |
| ADediting_1397437 | chr8_23414149_- | SINE | Alu | Name=AluSz |
| ADediting_1397438 | chr8_23414154_- | SINE | Alu | Name=AluSz |
| ADediting_1397439 | chr8_23414164_- | SINE | Alu | Name=AluSz |
| ADediting_1397440 | chr8_23414173_- | SINE | Alu | Name=AluSz |
| ADediting_1397441 | chr8_23414187_- | SINE | Alu | Name=AluSz |
| ADediting_1397442 | chr8_23414192_- | SINE | Alu | Name=AluSz |
| ADediting_1397443 | chr8_23414194_- | SINE | Alu | Name=AluSz |
| ADediting_1397444 | chr8_23414210_- | SINE | Alu | Name=AluSz |
| ADediting_1397445 | chr8_23414211_- | SINE | Alu | Name=AluSz |
| ADediting_1397446 | chr8_23414212_- | SINE | Alu | Name=AluSz |
| ADediting_1397447 | chr8_23414218_- | SINE | Alu | Name=AluSz |
| ADediting_1397448 | chr8_23414220_- | SINE | Alu | Name=AluSz |
| ADediting_1397449 | chr8_23414221_- | SINE | Alu | Name=AluSz |
| ADediting_1397450 | chr8_23414235_- | SINE | Alu | Name=AluSz |
| ADediting_1397451 | chr8_23414236_- | SINE | Alu | Name=AluSz |
| ADediting_1397452 | chr8_23414244_- | SINE | Alu | Name=AluSz |
| ADediting_1397453 | chr8_23414291_- | SINE | Alu | Name=AluSz |
| ADediting_1397454 | chr8_23414653_- | SINE | Alu | Name=AluY |
| ADediting_1397455 | chr8_23414675_- | SINE | Alu | Name=AluY |
| ADediting_1397456 | chr8_23414730_- | SINE | Alu | Name=AluY |
| ADediting_1397457 | chr8_23414766_- | SINE | Alu | Name=AluY |
| ADediting_1397458 | chr8_23415178_- | SINE | Alu | Name=AluSx1 |
| ADediting_1397459 | chr8_23415183_- | SINE | Alu | Name=AluSx1 |
| ADediting_1397460 | chr8_23415285_- | SINE | Alu | Name=AluSx1 |
| ADediting_1397461 | chr8_23418627_- | SINE | Alu | Name=AluJo |
| ADediting_1397462 | chr8_23418636_- | SINE | Alu | Name=AluJo |
| ADediting_1397463 | chr8_23418639_- | SINE | Alu | Name=AluJo |
| ADediting_1397464 | chr8_23418717_- | SINE | Alu | Name=AluJo |
| ADediting_1397465 | chr8_23418762_- | SINE | Alu | Name=AluJo |
| ADediting_1397466 | chr8_23418776_- | SINE | Alu | Name=AluJo |
| ADediting_1397467 | chr8_23418821_- | SINE | Alu | Name=AluJo |
| ADediting_1397468 | chr8_23419905_- | SINE | Alu | Name=AluY |
| ADediting_1397469 | chr8_23420065_- | SINE | Alu | Name=AluY |
| ADediting_1397470 | chr8_23423183_- | SINE | Alu | Name=AluSc |
| ADediting_1397471 | chr8_23423380_- | SINE | Alu | Name=AluSc |
| ADediting_1397472 | chr8_23426167_- | SINE | Alu | Name=AluSg |
| ADediting_1397473 | chr8_23426299_- | SINE | Alu | Name=AluSg |
| ADediting_1397474 | chr8_23426308_- | SINE | Alu | Name=AluSg |
| ADediting_1397476 | chr8_23426869_- | SINE | Alu | Name=AluY |
| ADediting_1397477 | chr8_23426875_- | SINE | Alu | Name=AluY |
| ADediting_1397478 | chr8_23426881_- | SINE | Alu | Name=AluY |
| ADediting_1397479 | chr8_23426900_- | SINE | Alu | Name=AluY |
| ADediting_1397480 | chr8_23432559_- | SINE | Alu | Name=AluY |
| ADediting_1397481 | chr8_23432561_- | SINE | Alu | Name=AluY |
| ADediting_1397482 | chr8_23432566_- | SINE | Alu | Name=AluY |
| ADediting_1397483 | chr8_23432584_- | SINE | Alu | Name=AluY |
| ADediting_1397484 | chr8_23432599_- | SINE | Alu | Name=AluY |
| ADediting_1397485 | chr8_23432610_- | SINE | Alu | Name=AluY |
| ADediting_1397486 | chr8_23432637_- | SINE | Alu | Name=AluY |
| ADediting_1397487 | chr8_23432663_- | SINE | Alu | Name=AluY |
| ADediting_1397488 | chr8_23432669_- | SINE | Alu | Name=AluY |
| ADediting_1397489 | chr8_23432673_- | SINE | Alu | Name=AluY |
| ADediting_1397490 | chr8_23432727_- | SINE | Alu | Name=AluY |
| ADediting_1397491 | chr8_23432762_- | SINE | Alu | Name=AluY |
| ADediting_1397492 | chr8_23432765_- | SINE | Alu | Name=AluY |
| ADediting_1397493 | chr8_23432770_- | SINE | Alu | Name=AluY |
| ADediting_1397494 | chr8_23432779_- | SINE | Alu | Name=AluY |
| ADediting_1590244 | chr8_23412742_- | SINE | Alu | Name=AluJr |
| ADediting_1590245 | chr8_23426073_- | SINE | Alu | Name=AluSg |
| ADediting_1590246 | chr8_23426085_- | SINE | Alu | Name=AluSg |
| ADediting_1590247 | chr8_23426110_- | SINE | Alu | Name=AluSg |
| ADediting_1590248 | chr8_23426313_- | SINE | Alu | Name=AluSg |
| ADediting_1590249 | chr8_23426314_- | SINE | Alu | Name=AluSg |
| ADediting_1590250 | chr8_23426330_- | SINE | Alu | Name=AluSg |
| ADediting_1590251 | chr8_23426882_- | SINE | Alu | Name=AluY |
| ADediting_1590252 | chr8_23432713_- | SINE | Alu | Name=AluY |
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RNA A-to-I editing events in the alternative splicing sites for ENTPD4 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ENTPD4 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ENTPD4 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for ENTPD4 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1397481 | chr8_23432561_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-675-5p | chr8 | 23432556 | 23432562 | 7mer-1a | 23432556 | 23432578 | 141 | -23.91 |
| ADediting_1397483 | chr8_23432584_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-1281 | chr8 | 23432584 | 23432590 | 7mer-m8 | 23432583 | 23432599 | 141 | -17.01 |
| ADediting_1397484 | chr8_23432599_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-122-3p | chr8 | 23432598 | 23432604 | 7mer-m8 | 23432597 | 23432618 | 152 | -14.91 |
| ADediting_1397488 | chr8_23432669_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-578 | chr8 | 23432666 | 23432673 | 8mer-1a | 23432666 | 23432686 | 148 | -9.39 |
| ADediting_1397488 | chr8_23432669_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-643 | chr8 | 23432668 | 23432675 | 8mer-1a | 23432668 | 23432690 | 143 | -11.13 |
| ADediting_1397489 | chr8_23432673_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-153-5p | chr8 | 23432673 | 23432679 | 7mer-m8 | 23432672 | 23432694 | 144 | -8.17 |
| ADediting_1397489 | chr8_23432673_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-3680-3p | chr8 | 23432668 | 23432675 | 8mer-1a | 23432668 | 23432690 | 140 | -14.25 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-518a-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432778 | 145 | -17.15 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-518b | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432777 | 146 | -21.79 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-518c-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432778 | 146 | -18.98 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-518d-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432777 | 145 | -17.84 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-518e-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432779 | 144 | -18.65 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-518f-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432777 | 145 | -17.48 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-526a-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432777 | 146 | -17.71 |
| ADediting_1397492 | chr8_23432765_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-371a-3p | chr8 | 23432760 | 23432766 | 7mer-m8 | 23432759 | 23432781 | 145 | -17.36 |
| ADediting_1397493 | chr8_23432770_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-8052 | chr8 | 23432765 | 23432771 | 7mer-1a | 23432765 | 23432783 | 140 | -24.15 |
| ADediting_1397494 | chr8_23432779_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4634 | chr8 | 23432775 | 23432781 | 7mer-m8 | 23432774 | 23432793 | 151 | -24.94 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1397482 | chr8_23432566_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4638-5p | chr8 | 23432564 | 23432571 | 8mer-1a | 23432564 | 23432583 | 146 | -21.99 |
| ADediting_1397483 | chr8_23432584_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-3194-3p | chr8 | 23432580 | 23432586 | 7mer-m8 | 23432579 | 23432600 | 154 | -22.72 |
| ADediting_1397483 | chr8_23432584_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6836-3p | chr8 | 23432584 | 23432590 | 7mer-m8 | 23432583 | 23432603 | 147 | -20.1 |
| ADediting_1397484 | chr8_23432599_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-1206 | chr8 | 23432594 | 23432600 | 7mer-m8 | 23432593 | 23432613 | 145 | -11.84 |
| ADediting_1397485 | chr8_23432610_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-1976 | chr8 | 23432605 | 23432612 | 8mer-1a | 23432605 | 23432625 | 153 | -25.04 |
| ADediting_1397485 | chr8_23432610_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6747-3p | chr8 | 23432607 | 23432614 | 8mer-1a | 23432607 | 23432629 | 149 | -23.42 |
| ADediting_1397487 | chr8_23432663_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4735-5p | chr8 | 23432662 | 23432668 | 7mer-m8 | 23432661 | 23432682 | 140 | -4.28 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-302a-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432779 | 143 | -14.98 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-302b-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432780 | 141 | -9.83 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-302c-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432778 | 145 | -11.96 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-302d-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432785 | 148 | -13.74 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-302e | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432774 | 141 | -8.62 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-372-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432785 | 155 | -20.46 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-512-3p | chr8 | 23432760 | 23432766 | 7mer-m8 | 23432759 | 23432780 | 149 | -15.51 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-519d-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432777 | 146 | -14.53 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520a-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432779 | 140 | -11.03 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520b-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432777 | 141 | -16.52 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520c-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432778 | 146 | -16.52 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520d-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432779 | 140 | -15.12 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520e-3p | chr8 | 23432759 | 23432765 | 7mer-m8 | 23432758 | 23432778 | 140 | -13.32 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520g-3p | chr8 | 23432757 | 23432763 | 7mer-m8 | 23432756 | 23432778 | 151 | -16.77 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-520h | chr8 | 23432757 | 23432763 | 7mer-m8 | 23432756 | 23432777 | 150 | -15.08 |
| ADediting_1397491 | chr8_23432762_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-526b-3p | chr8 | 23432758 | 23432764 | 7mer-m8 | 23432757 | 23432777 | 146 | -16.66 |
| ADediting_1397492 | chr8_23432765_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-5089-5p | chr8 | 23432765 | 23432771 | 7mer-m8 | 23432764 | 23432786 | 148 | -14.13 |
| ADediting_1397492 | chr8_23432765_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-512-3p | chr8 | 23432760 | 23432766 | 7mer-m8 | 23432759 | 23432780 | 149 | -15.51 |
| ADediting_1397492 | chr8_23432765_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6506-5p | chr8 | 23432764 | 23432770 | 7mer-m8 | 23432763 | 23432785 | 144 | -13.78 |
| ADediting_1397493 | chr8_23432770_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-10399-5p | chr8 | 23432769 | 23432775 | 7mer-m8 | 23432768 | 23432789 | 144 | -11.2 |
| ADediting_1397493 | chr8_23432770_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-5089-5p | chr8 | 23432765 | 23432771 | 7mer-m8 | 23432764 | 23432786 | 148 | -14.13 |
| ADediting_1397493 | chr8_23432770_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6504-3p | chr8 | 23432769 | 23432775 | 7mer-m8 | 23432768 | 23432789 | 148 | -14.35 |
| ADediting_1397494 | chr8_23432779_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6807-5p | chr8 | 23432779 | 23432785 | 7mer-m8 | 23432778 | 23432800 | 144 | -24.46 |
| ADediting_1590252 | chr8_23432713_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-1193 | chr8 | 23432710 | 23432716 | 7mer-m8 | 23432709 | 23432734 | 143 | -20.63 |
| ADediting_1590252 | chr8_23432713_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-2392 | chr8 | 23432709 | 23432715 | 7mer-m8 | 23432708 | 23432727 | 142 | -17.64 |
| ADediting_1590252 | chr8_23432713_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6843-3p | chr8 | 23432713 | 23432719 | 7mer-m8 | 23432712 | 23432730 | 150 | -20.32 |
| ADediting_1590252 | chr8_23432713_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-6848-3p | chr8 | 23432713 | 23432719 | 7mer-m8 | 23432712 | 23432728 | 142 | -15.23 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4477b | chr8 | 23431356 | 23431362 | 7mer-m8 | 23431355 | 23431377 | 141 | -10.83 |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-337-3p | chr8 | 23431544 | 23431551 | 8mer-1a | 23431544 | 23431568 | 158 | -23.05 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-381-3p | chr8 | 23431195 | 23431201 | 7mer-m8 | 23431194 | 23431215 | 148 | -19.32 |
| ADediting_286380 | chr11_79422188_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-5579-3p | chr8 | 23431500 | 23431507 | 8mer-1a | 23431500 | 23431521 | 150 | -14.4 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4775 | chr8 | 23429185 | 23429192 | 8mer-1a | 23429185 | 23429206 | 151 | -11.66 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4775 | chr8 | 23429525 | 23429531 | 7mer-m8 | 23429524 | 23429545 | 158 | -10.2 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-5688 | chr8 | 23429371 | 23429377 | 7mer-m8 | 23429370 | 23429391 | 145 | -8.88 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-641 | chr8 | 23429288 | 23429294 | 7mer-m8 | 23429287 | 23429310 | 152 | -10.2 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-641 | chr8 | 23429288 | 23429294 | 7mer-m8 | 23429287 | 23429310 | 152 | -10.2 |
| ADediting_527135 | chr16_24203190_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-1273h-3p | chr8 | 23430222 | 23430228 | 7mer-m8 | 23430221 | 23430239 | 145 | -19.81 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000197217.13 | ENST00000358689.9 | ENTPD4-202 | hsa-miR-4775 | chr8 | 23429357 | 23429363 | 7mer-m8 | 23429356 | 23429376 | 146 | -6.12 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ENTPD4 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000358689.9 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1397480 | ENST00000358689.9 | chr8_23432559_- | 2406 | -1787.44 | -1786.34 | -1796.44 |
| ADediting_1397481 | ENST00000358689.9 | chr8_23432561_- | 2404 | -1786.14 | -1786.34 | -1796.44 |
| ADediting_1397482 | ENST00000358689.9 | chr8_23432566_- | 2399 | -1786.30 | -1786.34 | -1796.44 |
| ADediting_1397483 | ENST00000358689.9 | chr8_23432584_- | 2381 | -1787.70 | -1786.34 | -1796.44 |
| ADediting_1397484 | ENST00000358689.9 | chr8_23432599_- | 2366 | -1785.64 | -1786.34 | -1796.44 |
| ADediting_1397485 | ENST00000358689.9 | chr8_23432610_- | 2355 | -1785.64 | -1786.34 | -1796.44 |
| ADediting_1397486 | ENST00000358689.9 | chr8_23432637_- | 2328 | -1785.84 | -1786.34 | -1796.44 |
| ADediting_1397487 | ENST00000358689.9 | chr8_23432663_- | 2302 | -1786.04 | -1786.34 | -1796.44 |
| ADediting_1397488 | ENST00000358689.9 | chr8_23432669_- | 2296 | -1786.34 | -1786.34 | -1796.44 |
| ADediting_1397489 | ENST00000358689.9 | chr8_23432673_- | 2292 | -1786.34 | -1786.34 | -1796.44 |
| ADediting_1590252 | ENST00000358689.9 | chr8_23432713_- | 2252 | -1786.34 | -1786.34 | -1796.44 |
| ADediting_1397490 | ENST00000358689.9 | chr8_23432727_- | 2238 | -1785.64 | -1786.34 | -1796.44 |
| ADediting_1397491 | ENST00000358689.9 | chr8_23432762_- | 2203 | -1786.34 | -1786.34 | -1796.44 |
| ADediting_1397492 | ENST00000358689.9 | chr8_23432765_- | 2200 | -1785.64 | -1786.34 | -1796.44 |
| ADediting_1397493 | ENST00000358689.9 | chr8_23432770_- | 2195 | -1786.34 | -1786.34 | -1796.44 |
| ADediting_1397494 | ENST00000358689.9 | chr8_23432779_- | 2186 | -1790.54 | -1786.34 | -1796.44 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ENTPD4 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 6.60077366517532e-128 | 0.920717533866814 | 4.91022030852141e-99 | 0.874980219781572 | 0.0845223486572667 | 0.0981348567526883 |
| AC | 1.50701650858073e-93 | 0.904093613521 | 5.5788200179414e-86 | 0.888739761724321 | 2.05060573315754e-08 | 0.345415519976321 |
| PCC | 3.99406007351431e-68 | 0.894853263308114 | 3.97730427458634e-98 | 0.950801256689786 | 0.484042694198292 | 0.0509383425040807 |
| CER | 8.65853211900554e-56 | 0.901791336666636 | 5.85185505229558e-24 | 0.706233334154563 | 0.308194782661728 | 0.0837567737454205 |
| TCX | 2.22704821677597e-59 | 0.912655533403151 | 6.08716013965758e-29 | 0.755232214536032 | 0.60529970412805 | 0.0425327879343998 |
| FP | 1.97020445336074e-22 | 0.646334607126679 | 5.90373342486998e-36 | 0.768429545481453 | 0.574753243922775 | 0.0423329862915475 |
| IFG | 3.21457227978734e-07 | 0.828181037589249 | 0.000100028192200769 | 0.699408491621501 | 0.935274728645217 | 0.0171172595106611 |
| PG | 1.65739746419574e-63 | 0.886564108496216 | 7.35998667849295e-46 | 0.816973787404715 | 0.403935767963246 | -0.0615536738281772 |
| STG | 4.57585482120531e-26 | 0.863245762764512 | 3.29199168463201e-21 | 0.815923195991571 | 0.77163365899559 | -0.0321410493139004 |
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Relation with AD stages for ENTPD4 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for ENTPD4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ENTPD4 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| ENTPD4 | C0036341 | Schizophrenia | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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