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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for APBA3

check button Gene summary
Gene informationGene symbol

APBA3

Gene ID

9546

Gene nameamyloid beta precursor protein binding family A member 3
SynonymsMGC:15815|X11L2|mint3
Cytomap

19p13.3

Type of geneprotein-coding
Descriptionamyloid-beta A4 precursor protein-binding family A member 3X11-like 2 proteinadapter protein X11gammaamyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2)mint-3neuron-specific X11L2 proteinneuronal munc18-1-interacting protein
Modification date20200313
UniProtAcc

O96018,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
APBA3

GO:0043086

negative regulation of catalytic activity

19726677


Top

RNA A-to-I events for APBA3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_745059(3752102, -), ADediting_745060(3752196, -), ADediting_745062(3753399, -), ADediting_745063(3753551, -), ADediting_745244(3756593, -), ADediting_745245(3756601, -), ADediting_745246(3756610, -), ADediting_745247(3756611, -), ADediting_745248(3756623, -), ADediting_745249(3756640, -), ADediting_745250(3756641, -), ADediting_745251(3756647, -), ADediting_745252(3756671, -), ADediting_745253(3756676, -), ADediting_745254(3756679, -), ADediting_745255(3756685, -), ADediting_745256(3756721, -), ADediting_745257(3757180, -), ADediting_745258(3757181, -), ADediting_745259(3757189, -), ADediting_745260(3757214, -), ADediting_745261(3757220, -), ADediting_745262(3757227, -), ADediting_745263(3757231, -), ADediting_745264(3757236, -), ADediting_745265(3757237, -), ADediting_745266(3757239, -), ADediting_745267(3757247, -), ADediting_745268(3757258, -), ADediting_745269(3757262, -), ADediting_745270(3757286, -), ADediting_745271(3757289, -), ADediting_745272(3757302, -), ADediting_745273(3757303, -), ADediting_745274(3757306, -), ADediting_745275(3757363, -), ADediting_745276(3757364, -), ADediting_745277(3757373, -), ADediting_745278(3757374, -), ADediting_745279(3757380, -), ADediting_745280(3757386, -), ADediting_745281(3757477, -), ADediting_745282(3757488, -), ADediting_745283(3757489, -), ADediting_745284(3757490, -), ADediting_745285(3757527, -), ADediting_745286(3757529, -), ADediting_745287(3757552, -), ADediting_745288(3757566, -), ADediting_745289(3757569, -), ADediting_745290(3757577, -), ADediting_745291(3757583, -), ADediting_745292(3757584, -), ADediting_745293(3757588, -), ADediting_745294(3757597, -), ADediting_745295(3757607, -), ADediting_745296(3757608, -), ADediting_745297(3757610, -), ADediting_745298(3757615, -), ADediting_745299(3757620, -), ADediting_745300(3757632, -), ADediting_745301(3757649, -), ADediting_745302(3757680, -), ADediting_745303(3757685, -), ADediting_745304(3757970, -), ADediting_745305(3758063, -), ADediting_745306(3758072, -), ADediting_745307(3758073, -), ADediting_745308(3758086, -), ADediting_745309(3758091, -), ADediting_745310(3758099, -), ADediting_745311(3758103, -), ADediting_745312(3758104, -), ADediting_745313(3758106, -), ADediting_745314(3758108, -), ADediting_745315(3758113, -), ADediting_745316(3758114, -), ADediting_745317(3758117, -), ADediting_745318(3758128, -), ADediting_745319(3758129, -), ADediting_745320(3758139, -), ADediting_745321(3758163, -), ADediting_745322(3758168, -), ADediting_745323(3758171, -), ADediting_745324(3758176, -), ADediting_745325(3758184, -), ADediting_745326(3758185, -), ADediting_745327(3758198, -), ADediting_745328(3758201, -), ADediting_745329(3758206, -), ADediting_745330(3758207, -), ADediting_745331(3758209, -), ADediting_745332(3758296, -), ADediting_745333(3758303, -), ADediting_745334(3758351, -), ADediting_745335(3758356, -), ADediting_745336(3758364, -), ADediting_745337(3758383, -), ADediting_745338(3758387, -), ADediting_745339(3758397, -), ADediting_745340(3758419, -), ADediting_745341(3758423, -), ADediting_745342(3758439, -), ADediting_745343(3758440, -), ADediting_745344(3758442, -), ADediting_745345(3758455, -), ADediting_745346(3758456, -), ADediting_745347(3758459, -), ADediting_745348(3758463, -), ADediting_745349(3758473, -), ADediting_745350(3758476, -), ADediting_745351(3758505, -), ADediting_745352(3758526, -), ADediting_745353(3758531, -), ADediting_745354(3758532, -), ADediting_745355(3758538, -), ADediting_745356(3758620, -), ADediting_745357(3758623, -), ADediting_745358(3758629, -), ADediting_745359(3758635, -), ADediting_745360(3758636, -), ADediting_745361(3758686, -), ADediting_745362(3758698, -), ADediting_745363(3758712, -), ADediting_745364(3758715, -), ADediting_745365(3758730, -), ADediting_745366(3758734, -), ADediting_745367(3758743, -), ADediting_745368(3758778, -), ADediting_745369(3758795, -), ADediting_745370(3758815, -), ADediting_745371(3758831, -), ADediting_745372(3758853, -), ADediting_745373(3758965, -), ADediting_745374(3758970, -), ADediting_745375(3758974, -), ADediting_745376(3758987, -), ADediting_745377(3759004, -), ADediting_745378(3759018, -), ADediting_745379(3759019, -), ADediting_745380(3759029, -), ADediting_745381(3759039, -), ADediting_745382(3759042, -), ADediting_745383(3759085, -), ADediting_745384(3759094, -), ADediting_745385(3759105, -), ADediting_745386(3759107, -), ADediting_745387(3759112, -), ADediting_745388(3759117, -), ADediting_745389(3759119, -), ADediting_745390(3759120, -), ADediting_745391(3759121, -), ADediting_745392(3759129, -), ADediting_745393(3759134, -), ADediting_745394(3759146, -), ADediting_745395(3759147, -), ADediting_745396(3759153, -), ADediting_745397(3759177, -), ADediting_745398(3759191, -), ADediting_745399(3759207, -), ADediting_745400(3759509, -), ADediting_745401(3759517, -), ADediting_1555655(3756636, -), ADediting_1555656(3756660, -), ADediting_1555657(3756697, -), ADediting_1555658(3757125, -), ADediting_1555659(3757398, -), ADediting_1555660(3757491, -), ADediting_1555661(3757540, -), ADediting_1555662(3757686, -), ADediting_1555663(3758374, -), ADediting_1555664(3758391, -), ADediting_1555665(3758427, -), ADediting_1555666(3758564, -), ADediting_1555667(3758840, -), ADediting_1555668(3758845, -), ADediting_1555669(3758857, -), ADediting_1555670(3758979, -), ADediting_1555671(3759030, -), ADediting_1555672(3759056, -), ADediting_1555673(3759166, -), ADediting_1631394(3756583, -),

Top

RNA editing positional annotations for APBA3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_745059chr19_3752102_-intronic
ADediting_745060chr19_3752196_-intronic
ADediting_745062chr19_3753399_-intronic
ADediting_745063chr19_3753551_-intronic
ADediting_745244chr19_3756593_-ncRNA_exonic
ADediting_745245chr19_3756601_-ncRNA_exonic
ADediting_745246chr19_3756610_-ncRNA_exonic
ADediting_745247chr19_3756611_-ncRNA_exonic
ADediting_745248chr19_3756623_-ncRNA_exonic
ADediting_745249chr19_3756640_-ncRNA_exonic
ADediting_745250chr19_3756641_-ncRNA_exonic
ADediting_745251chr19_3756647_-ncRNA_exonic
ADediting_745252chr19_3756671_-intronic
ADediting_745253chr19_3756676_-intronic
ADediting_745254chr19_3756679_-intronic
ADediting_745255chr19_3756685_-intronic
ADediting_745256chr19_3756721_-intronic
ADediting_745257chr19_3757180_-intronic
ADediting_745258chr19_3757181_-intronic
ADediting_745259chr19_3757189_-intronic
ADediting_745260chr19_3757214_-intronic
ADediting_745261chr19_3757220_-intronic
ADediting_745262chr19_3757227_-intronic
ADediting_745263chr19_3757231_-intronic
ADediting_745264chr19_3757236_-intronic
ADediting_745265chr19_3757237_-intronic
ADediting_745266chr19_3757239_-intronic
ADediting_745267chr19_3757247_-intronic
ADediting_745268chr19_3757258_-intronic
ADediting_745269chr19_3757262_-intronic
ADediting_745270chr19_3757286_-intronic
ADediting_745271chr19_3757289_-intronic
ADediting_745272chr19_3757302_-intronic
ADediting_745273chr19_3757303_-intronic
ADediting_745274chr19_3757306_-intronic
ADediting_745275chr19_3757363_-intronic
ADediting_745276chr19_3757364_-intronic
ADediting_745277chr19_3757373_-intronic
ADediting_745278chr19_3757374_-intronic
ADediting_745279chr19_3757380_-intronic
ADediting_745280chr19_3757386_-intronic
ADediting_745281chr19_3757477_-intronic
ADediting_745282chr19_3757488_-intronic
ADediting_745283chr19_3757489_-intronic
ADediting_745284chr19_3757490_-intronic
ADediting_745285chr19_3757527_-intronic
ADediting_745286chr19_3757529_-intronic
ADediting_745287chr19_3757552_-intronic
ADediting_745288chr19_3757566_-intronic
ADediting_745289chr19_3757569_-intronic
ADediting_745290chr19_3757577_-intronic
ADediting_745291chr19_3757583_-intronic
ADediting_745292chr19_3757584_-intronic
ADediting_745293chr19_3757588_-intronic
ADediting_745294chr19_3757597_-intronic
ADediting_745295chr19_3757607_-intronic
ADediting_745296chr19_3757608_-intronic
ADediting_745297chr19_3757610_-intronic
ADediting_745298chr19_3757615_-intronic
ADediting_745299chr19_3757620_-intronic
ADediting_745300chr19_3757632_-intronic
ADediting_745301chr19_3757649_-intronic
ADediting_745302chr19_3757680_-intronic
ADediting_745303chr19_3757685_-intronic
ADediting_745304chr19_3757970_-intronic
ADediting_745305chr19_3758063_-intronic
ADediting_745306chr19_3758072_-intronic
ADediting_745307chr19_3758073_-intronic
ADediting_745308chr19_3758086_-intronic
ADediting_745309chr19_3758091_-intronic
ADediting_745310chr19_3758099_-intronic
ADediting_745311chr19_3758103_-intronic
ADediting_745312chr19_3758104_-intronic
ADediting_745313chr19_3758106_-intronic
ADediting_745314chr19_3758108_-intronic
ADediting_745315chr19_3758113_-intronic
ADediting_745316chr19_3758114_-intronic
ADediting_745317chr19_3758117_-intronic
ADediting_745318chr19_3758128_-intronic
ADediting_745319chr19_3758129_-intronic
ADediting_745320chr19_3758139_-intronic
ADediting_745321chr19_3758163_-intronic
ADediting_745322chr19_3758168_-intronic
ADediting_745323chr19_3758171_-intronic
ADediting_745324chr19_3758176_-intronic
ADediting_745325chr19_3758184_-intronic
ADediting_745326chr19_3758185_-intronic
ADediting_745327chr19_3758198_-intronic
ADediting_745328chr19_3758201_-intronic
ADediting_745329chr19_3758206_-intronic
ADediting_745330chr19_3758207_-intronic
ADediting_745331chr19_3758209_-intronic
ADediting_745332chr19_3758296_-intronic
ADediting_745333chr19_3758303_-intronic
ADediting_745334chr19_3758351_-intronic
ADediting_745335chr19_3758356_-intronic
ADediting_745336chr19_3758364_-intronic
ADediting_745337chr19_3758383_-intronic
ADediting_745338chr19_3758387_-intronic
ADediting_745339chr19_3758397_-intronic
ADediting_745340chr19_3758419_-intronic
ADediting_745341chr19_3758423_-intronic
ADediting_745342chr19_3758439_-intronic
ADediting_745343chr19_3758440_-intronic
ADediting_745344chr19_3758442_-intronic
ADediting_745345chr19_3758455_-intronic
ADediting_745346chr19_3758456_-intronic
ADediting_745347chr19_3758459_-intronic
ADediting_745348chr19_3758463_-intronic
ADediting_745349chr19_3758473_-intronic
ADediting_745350chr19_3758476_-intronic
ADediting_745351chr19_3758505_-intronic
ADediting_745352chr19_3758526_-intronic
ADediting_745353chr19_3758531_-intronic
ADediting_745354chr19_3758532_-intronic
ADediting_745355chr19_3758538_-intronic
ADediting_745356chr19_3758620_-intronic
ADediting_745357chr19_3758623_-intronic
ADediting_745358chr19_3758629_-intronic
ADediting_745359chr19_3758635_-intronic
ADediting_745360chr19_3758636_-intronic
ADediting_745361chr19_3758686_-intronic
ADediting_745362chr19_3758698_-intronic
ADediting_745363chr19_3758712_-intronic
ADediting_745364chr19_3758715_-intronic
ADediting_745365chr19_3758730_-intronic
ADediting_745366chr19_3758734_-intronic
ADediting_745367chr19_3758743_-intronic
ADediting_745368chr19_3758778_-intronic
ADediting_745369chr19_3758795_-intronic
ADediting_745370chr19_3758815_-intronic
ADediting_745371chr19_3758831_-intronic
ADediting_745372chr19_3758853_-intronic
ADediting_745373chr19_3758965_-intronic
ADediting_745374chr19_3758970_-intronic
ADediting_745375chr19_3758974_-intronic
ADediting_745376chr19_3758987_-intronic
ADediting_745377chr19_3759004_-intronic
ADediting_745378chr19_3759018_-intronic
ADediting_745379chr19_3759019_-intronic
ADediting_745380chr19_3759029_-intronic
ADediting_745381chr19_3759039_-intronic
ADediting_745382chr19_3759042_-intronic
ADediting_745383chr19_3759085_-intronic
ADediting_745384chr19_3759094_-intronic
ADediting_745385chr19_3759105_-intronic
ADediting_745386chr19_3759107_-intronic
ADediting_745387chr19_3759112_-intronic
ADediting_745388chr19_3759117_-intronic
ADediting_745389chr19_3759119_-intronic
ADediting_745390chr19_3759120_-intronic
ADediting_745391chr19_3759121_-intronic
ADediting_745392chr19_3759129_-intronic
ADediting_745393chr19_3759134_-intronic
ADediting_745394chr19_3759146_-intronic
ADediting_745395chr19_3759147_-intronic
ADediting_745396chr19_3759153_-intronic
ADediting_745397chr19_3759177_-intronic
ADediting_745398chr19_3759191_-intronic
ADediting_745399chr19_3759207_-intronic
ADediting_745400chr19_3759509_-intronic
ADediting_745401chr19_3759517_-intronic
ADediting_1555655chr19_3756636_-ncRNA_exonic
ADediting_1555656chr19_3756660_-intronic
ADediting_1555657chr19_3756697_-intronic
ADediting_1555658chr19_3757125_-intronic
ADediting_1555659chr19_3757398_-intronic
ADediting_1555660chr19_3757491_-intronic
ADediting_1555661chr19_3757540_-intronic
ADediting_1555662chr19_3757686_-intronic
ADediting_1555663chr19_3758374_-intronic
ADediting_1555664chr19_3758391_-intronic
ADediting_1555665chr19_3758427_-intronic
ADediting_1555666chr19_3758564_-intronic
ADediting_1555667chr19_3758840_-intronic
ADediting_1555668chr19_3758845_-intronic
ADediting_1555669chr19_3758857_-intronic
ADediting_1555670chr19_3758979_-intronic
ADediting_1555671chr19_3759030_-intronic
ADediting_1555672chr19_3759056_-intronic
ADediting_1555673chr19_3759166_-intronic
ADediting_1631394chr19_3756583_-ncRNA_exonic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_745059chr19_3752102_-SINEAluName=AluJb
ADediting_745060chr19_3752196_-SINEAluName=AluJb
ADediting_745062chr19_3753399_-SINEAluName=AluJo
ADediting_745063chr19_3753551_-SINEAluName=AluJo
ADediting_745244chr19_3756593_-SINEAluName=AluSx3
ADediting_745245chr19_3756601_-SINEAluName=AluSx3
ADediting_745246chr19_3756610_-SINEAluName=AluSx3
ADediting_745247chr19_3756611_-SINEAluName=AluSx3
ADediting_745248chr19_3756623_-SINEAluName=AluSx3
ADediting_745249chr19_3756640_-SINEAluName=AluSx3
ADediting_745250chr19_3756641_-SINEAluName=AluSx3
ADediting_745251chr19_3756647_-SINEAluName=AluSx3
ADediting_745252chr19_3756671_-SINEAluName=AluSx3
ADediting_745253chr19_3756676_-SINEAluName=AluSx3
ADediting_745254chr19_3756679_-SINEAluName=AluSx3
ADediting_745255chr19_3756685_-SINEAluName=AluSx3
ADediting_745256chr19_3756721_-SINEAluName=AluSx3
ADediting_745257chr19_3757180_-SINEAluName=AluJo
ADediting_745258chr19_3757181_-SINEAluName=AluJo
ADediting_745259chr19_3757189_-SINEAluName=AluJo
ADediting_745260chr19_3757214_-SINEAluName=AluJo
ADediting_745261chr19_3757220_-SINEAluName=AluJo
ADediting_745262chr19_3757227_-SINEAluName=AluJo
ADediting_745263chr19_3757231_-SINEAluName=AluJo
ADediting_745264chr19_3757236_-SINEAluName=AluJo
ADediting_745265chr19_3757237_-SINEAluName=AluJo
ADediting_745266chr19_3757239_-SINEAluName=AluJo
ADediting_745267chr19_3757247_-SINEAluName=AluJo
ADediting_745268chr19_3757258_-SINEAluName=AluJo
ADediting_745269chr19_3757262_-SINEAluName=AluJo
ADediting_745270chr19_3757286_-SINEAluName=AluJo
ADediting_745271chr19_3757289_-SINEAluName=AluJo
ADediting_745272chr19_3757302_-SINEAluName=AluJo
ADediting_745273chr19_3757303_-SINEAluName=AluJo
ADediting_745274chr19_3757306_-SINEAluName=AluJo
ADediting_745275chr19_3757363_-SINEAluName=AluJo
ADediting_745276chr19_3757364_-SINEAluName=AluJo
ADediting_745277chr19_3757373_-SINEAluName=AluJo
ADediting_745278chr19_3757374_-SINEAluName=AluJo
ADediting_745279chr19_3757380_-SINEAluName=AluJo
ADediting_745280chr19_3757386_-SINEAluName=AluJo
ADediting_745281chr19_3757477_-SINEAluName=AluSg4
ADediting_745282chr19_3757488_-SINEAluName=AluSg4
ADediting_745283chr19_3757489_-SINEAluName=AluSg4
ADediting_745284chr19_3757490_-SINEAluName=AluSg4
ADediting_745285chr19_3757527_-SINEAluName=AluSg4
ADediting_745286chr19_3757529_-SINEAluName=AluSg4
ADediting_745287chr19_3757552_-SINEAluName=AluSg4
ADediting_745288chr19_3757566_-SINEAluName=AluSg4
ADediting_745289chr19_3757569_-SINEAluName=AluSg4
ADediting_745290chr19_3757577_-SINEAluName=AluSg4
ADediting_745291chr19_3757583_-SINEAluName=AluSg4
ADediting_745292chr19_3757584_-SINEAluName=AluSg4
ADediting_745293chr19_3757588_-SINEAluName=AluSg4
ADediting_745294chr19_3757597_-SINEAluName=AluSg4
ADediting_745295chr19_3757607_-SINEAluName=AluSg4
ADediting_745296chr19_3757608_-SINEAluName=AluSg4
ADediting_745297chr19_3757610_-SINEAluName=AluSg4
ADediting_745298chr19_3757615_-SINEAluName=AluSg4
ADediting_745299chr19_3757620_-SINEAluName=AluSg4
ADediting_745300chr19_3757632_-SINEAluName=AluSg4
ADediting_745301chr19_3757649_-SINEAluName=AluSg4
ADediting_745302chr19_3757680_-SINEAluName=AluSg4
ADediting_745303chr19_3757685_-SINEAluName=AluSg4
ADediting_745304chr19_3757970_-SINEAluName=AluSg
ADediting_745305chr19_3758063_-SINEAluName=AluSg
ADediting_745306chr19_3758072_-SINEAluName=AluSg
ADediting_745307chr19_3758073_-SINEAluName=AluSg
ADediting_745308chr19_3758086_-SINEAluName=AluSg
ADediting_745309chr19_3758091_-SINEAluName=AluSg
ADediting_745310chr19_3758099_-SINEAluName=AluSg
ADediting_745311chr19_3758103_-SINEAluName=AluSg
ADediting_745312chr19_3758104_-SINEAluName=AluSg
ADediting_745313chr19_3758106_-SINEAluName=AluSg
ADediting_745314chr19_3758108_-SINEAluName=AluSg
ADediting_745315chr19_3758113_-SINEAluName=AluSg
ADediting_745316chr19_3758114_-SINEAluName=AluSg
ADediting_745317chr19_3758117_-SINEAluName=AluSg
ADediting_745318chr19_3758128_-SINEAluName=AluSg
ADediting_745319chr19_3758129_-SINEAluName=AluSg
ADediting_745320chr19_3758139_-SINEAluName=AluSg
ADediting_745321chr19_3758163_-SINEAluName=AluSg
ADediting_745322chr19_3758168_-SINEAluName=AluSg
ADediting_745323chr19_3758171_-SINEAluName=AluSg
ADediting_745324chr19_3758176_-SINEAluName=AluSg
ADediting_745325chr19_3758184_-SINEAluName=AluSg
ADediting_745326chr19_3758185_-SINEAluName=AluSg
ADediting_745327chr19_3758198_-SINEAluName=AluSg
ADediting_745328chr19_3758201_-SINEAluName=AluSg
ADediting_745329chr19_3758206_-SINEAluName=AluSg
ADediting_745330chr19_3758207_-SINEAluName=AluSg
ADediting_745331chr19_3758209_-SINEAluName=AluSg
ADediting_745332chr19_3758296_-SINEAluName=AluJr
ADediting_745333chr19_3758303_-SINEAluName=AluJr
ADediting_745334chr19_3758351_-SINEAluName=AluJr
ADediting_745335chr19_3758356_-SINEAluName=AluJr
ADediting_745336chr19_3758364_-SINEAluName=AluJr
ADediting_745337chr19_3758383_-SINEAluName=AluJr
ADediting_745338chr19_3758387_-SINEAluName=AluJr
ADediting_745339chr19_3758397_-SINEAluName=AluJr
ADediting_745340chr19_3758419_-SINEAluName=AluJr
ADediting_745341chr19_3758423_-SINEAluName=AluJr
ADediting_745342chr19_3758439_-SINEAluName=AluJr
ADediting_745343chr19_3758440_-SINEAluName=AluJr
ADediting_745344chr19_3758442_-SINEAluName=AluJr
ADediting_745345chr19_3758455_-SINEAluName=AluJr
ADediting_745346chr19_3758456_-SINEAluName=AluJr
ADediting_745347chr19_3758459_-SINEAluName=AluJr
ADediting_745348chr19_3758463_-SINEAluName=AluJr
ADediting_745349chr19_3758473_-SINEAluName=AluJr
ADediting_745350chr19_3758476_-SINEAluName=AluJr
ADediting_745351chr19_3758505_-SINEAluName=AluJr
ADediting_745352chr19_3758526_-SINEAluName=AluJr
ADediting_745353chr19_3758531_-SINEAluName=AluJr
ADediting_745354chr19_3758532_-SINEAluName=AluJr
ADediting_745355chr19_3758538_-SINEAluName=AluJr
ADediting_745356chr19_3758620_-SINEAluName=AluSg
ADediting_745357chr19_3758623_-SINEAluName=AluSg
ADediting_745358chr19_3758629_-SINEAluName=AluSg
ADediting_745359chr19_3758635_-SINEAluName=AluSg
ADediting_745360chr19_3758636_-SINEAluName=AluSg
ADediting_745361chr19_3758686_-SINEAluName=AluSg
ADediting_745362chr19_3758698_-SINEAluName=AluSg
ADediting_745363chr19_3758712_-SINEAluName=AluSg
ADediting_745364chr19_3758715_-SINEAluName=AluSg
ADediting_745365chr19_3758730_-SINEAluName=AluSg
ADediting_745366chr19_3758734_-SINEAluName=AluSg
ADediting_745367chr19_3758743_-SINEAluName=AluSg
ADediting_745368chr19_3758778_-SINEAluName=AluSg
ADediting_745369chr19_3758795_-SINEAluName=AluSg
ADediting_745370chr19_3758815_-SINEAluName=AluSg
ADediting_745371chr19_3758831_-SINEAluName=AluSg
ADediting_745372chr19_3758853_-SINEAluName=AluSg
ADediting_745373chr19_3758965_-SINEAluName=AluJb
ADediting_745374chr19_3758970_-SINEAluName=AluJb
ADediting_745375chr19_3758974_-SINEAluName=AluJb
ADediting_745376chr19_3758987_-SINEAluName=AluJb
ADediting_745377chr19_3759004_-SINEAluName=AluJb
ADediting_745378chr19_3759018_-SINEAluName=AluJb
ADediting_745379chr19_3759019_-SINEAluName=AluJb
ADediting_745380chr19_3759029_-SINEAluName=AluJb
ADediting_745381chr19_3759039_-SINEAluName=AluJb
ADediting_745382chr19_3759042_-SINEAluName=AluJb
ADediting_745383chr19_3759085_-SINEAluName=AluJb
ADediting_745384chr19_3759094_-SINEAluName=AluJb
ADediting_745385chr19_3759105_-SINEAluName=AluJb
ADediting_745386chr19_3759107_-SINEAluName=AluJb
ADediting_745387chr19_3759112_-SINEAluName=AluJb
ADediting_745388chr19_3759117_-SINEAluName=AluJb
ADediting_745389chr19_3759119_-SINEAluName=AluJb
ADediting_745390chr19_3759120_-SINEAluName=AluJb
ADediting_745391chr19_3759121_-SINEAluName=AluJb
ADediting_745392chr19_3759129_-SINEAluName=AluJb
ADediting_745393chr19_3759134_-SINEAluName=AluJb
ADediting_745394chr19_3759146_-SINEAluName=AluJb
ADediting_745395chr19_3759147_-SINEAluName=AluJb
ADediting_745396chr19_3759153_-SINEAluName=AluJb
ADediting_745397chr19_3759177_-SINEAluName=AluJb
ADediting_745398chr19_3759191_-SINEAluName=AluJb
ADediting_745399chr19_3759207_-SINEAluName=AluJb
ADediting_1555655chr19_3756636_-SINEAluName=AluSx3
ADediting_1555656chr19_3756660_-SINEAluName=AluSx3
ADediting_1555657chr19_3756697_-SINEAluName=AluSx3
ADediting_1555658chr19_3757125_-SINEAluName=AluJo
ADediting_1555659chr19_3757398_-SINEAluName=AluJo
ADediting_1555660chr19_3757491_-SINEAluName=AluSg4
ADediting_1555661chr19_3757540_-SINEAluName=AluSg4
ADediting_1555662chr19_3757686_-SINEAluName=AluSg4
ADediting_1555663chr19_3758374_-SINEAluName=AluJr
ADediting_1555664chr19_3758391_-SINEAluName=AluJr
ADediting_1555665chr19_3758427_-SINEAluName=AluJr
ADediting_1555666chr19_3758564_-DNAhAT-CharlieName=MER58B
ADediting_1555667chr19_3758840_-SINEAluName=AluSg
ADediting_1555668chr19_3758845_-SINEAluName=AluSg
ADediting_1555669chr19_3758857_-SINEAluName=AluSg
ADediting_1555670chr19_3758979_-SINEAluName=AluJb
ADediting_1555671chr19_3759030_-SINEAluName=AluJb
ADediting_1555672chr19_3759056_-SINEAluName=AluJb
ADediting_1555673chr19_3759166_-SINEAluName=AluJb
ADediting_1631394chr19_3756583_-SINEAluName=AluSx3

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RNA A-to-I editing events in the alternative splicing sites for APBA3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for APBA3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for APBA3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for APBA3


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1535954chr14_101045974_+ENSG00000011132.12ENST00000316757.4APBA3-201hsa-miR-381-3pchr19375092037509267mer-m837509193750941159-25.21

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for APBA3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for APBA3

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_745246chr19_3756610_-0.000263154504255310.293802803285983.82626877537185e-050.329528026061250.2747594784666040.0897457862380688
CERADediting_745248chr19_3756623_-0.02518674598811120.1827615463860940.0001784802759789590.3013719856302690.7333000582597620.0280504034416535
DLPFCADediting_745251chr19_3756647_-0.003547502390844560.1651363494396960.473589492157990.04085107371100211.47868370495673e-110.371096377031039
DLPFCADediting_745255chr19_3756685_-0.1076642879016220.09155046788073730.782359204519707-0.01575237506968045.19111640268849e-080.303152108362039
CERADediting_745258chr19_3757181_-1.67948860307494e-060.3794391251746581.46823160994608e-060.3814087070842250.05010287004544140.160263781795716
TCXADediting_745258chr19_3757181_-0.9431525782030740.005871345495686410.140300782741017-0.1209757901946760.0001877396820453620.30039763420069
CERADediting_745259chr19_3757189_-0.00269618078550710.2433248988529684.69247422371399e-050.3259535528931790.07057836392011460.148061125476588
TCXADediting_745262chr19_3757227_-0.281661841021860.0884711087716910.252454422375565-0.09401990573248223.49260253291003e-080.431634356259983
TCXADediting_745264chr19_3757236_-0.3395433020722150.07851734124956070.202351391776255-0.1046830606955696.5855639569726e-050.319916630136699
TCXADediting_745265chr19_3757237_-0.5498124195686810.0492119429742540.257555807961477-0.09302025399592440.0001836742765720030.300819794797949
TCXADediting_745266chr19_3757239_-0.6523708264848150.03707833190241620.0519058282975901-0.1590386335066415.72614828771437e-070.394856527456181
TCXADediting_745267chr19_3757247_-0.3841180349811390.07156998458326660.10765677892043-0.131888031895915.80783487596983e-050.322170054021481
TCXADediting_745268chr19_3757258_-0.4874235196599850.05713013596159460.270895434811483-0.09046883272001829.40549187970569e-050.313426743758006
DLPFCADediting_745269chr19_3757262_-0.03328987285966220.1209391232411540.549899208004399-0.03408690490439749.37246306962314e-170.448602004765009
TCXADediting_745273chr19_3757303_-0.9208674804812310.008179452838284530.197223416777334-0.1058769551598417.12653719568854e-060.3574038755682
TCXADediting_745274chr19_3757306_-0.8694523906416140.01353204412253670.21908889397505-0.1009315885216453.3214979503633e-050.33198026333002
TCXADediting_745277chr19_3757373_-0.2176394804280440.1012481841572840.559437119111474-0.0480313772236252.84550326831559e-050.334637702159904
DLPFCADediting_745282chr19_3757488_-0.1453832204675640.08288965768710710.8222941285133-0.01280737081876611.2386052124609e-090.336302970102017
DLPFCADediting_745283chr19_3757489_-0.1305077700497310.08606991547485620.853710502156493-0.01051461894167845.34489766144158e-090.323801640230178
DLPFCADediting_745284chr19_3757490_-0.0576186746808720.1079533269546150.8723478368028910.009162661477101528.01135039603067e-110.358314049162202
DLPFCADediting_745286chr19_3757529_-0.3064015995970730.05827727575902210.646504370886485-0.02614926111644751.52712079594356e-120.38743212937743
DLPFCADediting_745293chr19_3757588_-0.04752899937403510.1126414186983970.23923025307510.06703976444529223.39982728575979e-130.397763324651757
DLPFCADediting_745295chr19_3757607_-0.3999636781014040.04797082120372710.464601288224882-0.04168489072276982.06020786832215e-090.332016258407487
DLPFCADediting_745297chr19_3757610_-0.1103135953005290.0908706770775370.714897668409395-0.02082876256104641.01996184371372e-100.356439978982692
DLPFCADediting_745299chr19_3757620_-0.03149622454740090.1221897263929380.3930428778444930.04867819128052972.67767398295188e-080.309330120524853
CERADediting_745337chr19_3758383_-0.002053219256821090.2497670009162285.58927865462703e-060.3612238361000740.003166394914301350.239444458511324
CERADediting_745352chr19_3758526_-5.04706946261959e-050.3246666900079041.35746080846267e-060.3825520876729210.08731676129614940.140081124361302
TCXADediting_745358chr19_3758629_-0.7070622871960060.03093574939863320.241761839525483-0.0961613943516014.84973887815204e-050.32537194164641

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.66595827614378e-100.346301224008813.40445986394864e-050.2330872839310172.64913004481629e-550.741428002428411
AC2.46330622175136e-070.3193890116076352.93009436381825e-050.2610050717357819.80202975678582e-190.520192104775994
PCC0.001807804026610840.2243513056905150.0007088121458715740.2429270400319589.71257567485367e-100.424120479617919
CER5.50315185833377e-070.3954109568590588.45299741351399e-140.5607787500394880.000706736747326770.273538186556054
TCX0.003667710822225550.235842963892440.704251145736708-0.03124706968831177.45206017586781e-210.669558979591855
FP2.07071673837831e-100.4534407659593421.80624612037898e-060.3489694798764561.44699749908585e-130.517223443996303
IFG0.0007881202121774970.6273968852593576.41983543437867e-060.7711647760392170.00979366600505810.506394875384446
PG0.546455756341031-0.04449800265655640.6663497952389020.03182091713978051.36014873025696e-100.448531746171864
STG0.01073611292913520.2770357134293610.4339549929816120.08650739706255294.50734733617416e-060.476927694241867

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Relation with AD stages for APBA3

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_745375chr19_3758974_-0.0008720729770364530.315756358271691
CERADediting_745389chr19_3759119_-0.0009924900016072050.312497409266853

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER8.77385904424585e-050.368342383935767
TCX4.64200458414829e-060.428325316068421

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RelatedDrugs for APBA3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for APBA3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource