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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for CIAO1

check button Gene summary
Gene informationGene symbol

CIAO1

Gene ID

9391

Gene namecytosolic iron-sulfur assembly component 1
SynonymsCIA1|WDR39
Cytomap

2q11.2

Type of geneprotein-coding
Descriptionprobable cytosolic iron-sulfur protein assembly protein CIAO1WD repeat domain 39WD repeat-containing protein 39WD40 protein Ciao1cytosolic iron-sulfur protein assembly 1 homolog
Modification date20200313
UniProtAcc

O76071,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for CIAO1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_908277(96268099, +), ADediting_908278(96268144, +), ADediting_908279(96268167, +), ADediting_908280(96268170, +), ADediting_908281(96268193, +), ADediting_908282(96268202, +), ADediting_908283(96268206, +), ADediting_908284(96269671, +), ADediting_908285(96269679, +), ADediting_908286(96269717, +), ADediting_908287(96269727, +), ADediting_908288(96269728, +), ADediting_908289(96269777, +), ADediting_908290(96269789, +), ADediting_908291(96269813, +), ADediting_908292(96269814, +), ADediting_908293(96269821, +), ADediting_908294(96269827, +), ADediting_908295(96269830, +), ADediting_908296(96269852, +), ADediting_908297(96269856, +), ADediting_908298(96269868, +), ADediting_908299(96269876, +), ADediting_908300(96269881, +), ADediting_908301(96269892, +), ADediting_908302(96269905, +), ADediting_908303(96269906, +), ADediting_908304(96269907, +), ADediting_908305(96269919, +), ADediting_908306(96269921, +), ADediting_908307(96269925, +), ADediting_908308(96270229, +), ADediting_908309(96270251, +), ADediting_908310(96270252, +), ADediting_908311(96270257, +), ADediting_908312(96270258, +), ADediting_908313(96270268, +), ADediting_908314(96270273, +), ADediting_908315(96270274, +), ADediting_908316(96270279, +), ADediting_908317(96270283, +), ADediting_908318(96270290, +), ADediting_908319(96270295, +), ADediting_908320(96270303, +), ADediting_908321(96270304, +), ADediting_908322(96270309, +), ADediting_908323(96270318, +), ADediting_908324(96270319, +), ADediting_908325(96270321, +), ADediting_908326(96270329, +), ADediting_908327(96270340, +), ADediting_908328(96270345, +), ADediting_908329(96270346, +), ADediting_908330(96270353, +), ADediting_908331(96270354, +), ADediting_908332(96270358, +), ADediting_908333(96270374, +), ADediting_908334(96270378, +), ADediting_908335(96270382, +), ADediting_908336(96270383, +), ADediting_908337(96270388, +), ADediting_908338(96270392, +), ADediting_908339(96270396, +), ADediting_908340(96270423, +), ADediting_908341(96270447, +), ADediting_908342(96270452, +), ADediting_908343(96270488, +), ADediting_908344(96270554, +), ADediting_908345(96270555, +), ADediting_908346(96270581, +), ADediting_908347(96270609, +), ADediting_908348(96270623, +), ADediting_908349(96270624, +), ADediting_908350(96270631, +), ADediting_908351(96270634, +), ADediting_908352(96270645, +), ADediting_908353(96270651, +), ADediting_908354(96270660, +), ADediting_908355(96270663, +), ADediting_908356(96270689, +), ADediting_908357(96270703, +), ADediting_908358(96270716, +), ADediting_908359(96270722, +), ADediting_908360(96270731, +), ADediting_908361(96270759, +), ADediting_908362(96270760, +), ADediting_908363(96270790, +), ADediting_908364(96270797, +), ADediting_908365(96270798, +), ADediting_1564954(96268168, +), ADediting_1564955(96272717, +), ADediting_1639728(96273577, +), ADediting_1639729(96273584, +),

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RNA editing positional annotations for CIAO1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_908277chr2_96268099_+intronic
ADediting_908278chr2_96268144_+intronic
ADediting_908279chr2_96268167_+intronic
ADediting_908280chr2_96268170_+intronic
ADediting_908281chr2_96268193_+intronic
ADediting_908282chr2_96268202_+intronic
ADediting_908283chr2_96268206_+intronic
ADediting_908284chr2_96269671_+intronic
ADediting_908285chr2_96269679_+intronic
ADediting_908286chr2_96269717_+intronic
ADediting_908287chr2_96269727_+intronic
ADediting_908288chr2_96269728_+intronic
ADediting_908289chr2_96269777_+intronic
ADediting_908290chr2_96269789_+intronic
ADediting_908291chr2_96269813_+intronic
ADediting_908292chr2_96269814_+intronic
ADediting_908293chr2_96269821_+intronic
ADediting_908294chr2_96269827_+intronic
ADediting_908295chr2_96269830_+intronic
ADediting_908296chr2_96269852_+intronic
ADediting_908297chr2_96269856_+intronic
ADediting_908298chr2_96269868_+intronic
ADediting_908299chr2_96269876_+intronic
ADediting_908300chr2_96269881_+intronic
ADediting_908301chr2_96269892_+intronic
ADediting_908302chr2_96269905_+intronic
ADediting_908303chr2_96269906_+intronic
ADediting_908304chr2_96269907_+intronic
ADediting_908305chr2_96269919_+intronic
ADediting_908306chr2_96269921_+intronic
ADediting_908307chr2_96269925_+intronic
ADediting_908308chr2_96270229_+intronic
ADediting_908309chr2_96270251_+intronic
ADediting_908310chr2_96270252_+intronic
ADediting_908311chr2_96270257_+intronic
ADediting_908312chr2_96270258_+intronic
ADediting_908313chr2_96270268_+intronic
ADediting_908314chr2_96270273_+intronic
ADediting_908315chr2_96270274_+intronic
ADediting_908316chr2_96270279_+intronic
ADediting_908317chr2_96270283_+intronic
ADediting_908318chr2_96270290_+intronic
ADediting_908319chr2_96270295_+intronic
ADediting_908320chr2_96270303_+intronic
ADediting_908321chr2_96270304_+intronic
ADediting_908322chr2_96270309_+intronic
ADediting_908323chr2_96270318_+intronic
ADediting_908324chr2_96270319_+intronic
ADediting_908325chr2_96270321_+intronic
ADediting_908326chr2_96270329_+intronic
ADediting_908327chr2_96270340_+intronic
ADediting_908328chr2_96270345_+intronic
ADediting_908329chr2_96270346_+intronic
ADediting_908330chr2_96270353_+intronic
ADediting_908331chr2_96270354_+intronic
ADediting_908332chr2_96270358_+intronic
ADediting_908333chr2_96270374_+intronic
ADediting_908334chr2_96270378_+intronic
ADediting_908335chr2_96270382_+intronic
ADediting_908336chr2_96270383_+intronic
ADediting_908337chr2_96270388_+intronic
ADediting_908338chr2_96270392_+intronic
ADediting_908339chr2_96270396_+intronic
ADediting_908340chr2_96270423_+intronic
ADediting_908341chr2_96270447_+intronic
ADediting_908342chr2_96270452_+intronic
ADediting_908343chr2_96270488_+intronic
ADediting_908344chr2_96270554_+intronic
ADediting_908345chr2_96270555_+intronic
ADediting_908346chr2_96270581_+intronic
ADediting_908347chr2_96270609_+intronic
ADediting_908348chr2_96270623_+intronic
ADediting_908349chr2_96270624_+intronic
ADediting_908350chr2_96270631_+intronic
ADediting_908351chr2_96270634_+intronic
ADediting_908352chr2_96270645_+intronic
ADediting_908353chr2_96270651_+intronic
ADediting_908354chr2_96270660_+intronic
ADediting_908355chr2_96270663_+intronic
ADediting_908356chr2_96270689_+intronic
ADediting_908357chr2_96270703_+intronic
ADediting_908358chr2_96270716_+intronic
ADediting_908359chr2_96270722_+intronic
ADediting_908360chr2_96270731_+intronic
ADediting_908361chr2_96270759_+intronic
ADediting_908362chr2_96270760_+intronic
ADediting_908363chr2_96270790_+intronic
ADediting_908364chr2_96270797_+intronic
ADediting_908365chr2_96270798_+intronic
ADediting_1564954chr2_96268168_+intronic
ADediting_1564955chr2_96272717_+UTR3
ADediting_1639728chr2_96273577_+UTR3
ADediting_1639729chr2_96273584_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_908277chr2_96268099_+SINEAluName=AluSx
ADediting_908278chr2_96268144_+SINEAluName=AluSx
ADediting_908279chr2_96268167_+SINEAluName=AluSx
ADediting_908280chr2_96268170_+SINEAluName=AluSx
ADediting_908281chr2_96268193_+SINEAluName=AluSx
ADediting_908282chr2_96268202_+SINEAluName=AluSx
ADediting_908283chr2_96268206_+SINEAluName=AluSx
ADediting_908284chr2_96269671_+SINEAluName=AluY
ADediting_908285chr2_96269679_+SINEAluName=AluY
ADediting_908286chr2_96269717_+SINEAluName=AluY
ADediting_908287chr2_96269727_+SINEAluName=AluY
ADediting_908288chr2_96269728_+SINEAluName=AluY
ADediting_908289chr2_96269777_+SINEAluName=AluY
ADediting_908290chr2_96269789_+SINEAluName=AluY
ADediting_908291chr2_96269813_+SINEAluName=AluY
ADediting_908292chr2_96269814_+SINEAluName=AluY
ADediting_908293chr2_96269821_+SINEAluName=AluY
ADediting_908294chr2_96269827_+SINEAluName=AluY
ADediting_908295chr2_96269830_+SINEAluName=AluY
ADediting_908296chr2_96269852_+SINEAluName=AluY
ADediting_908297chr2_96269856_+SINEAluName=AluY
ADediting_908298chr2_96269868_+SINEAluName=AluY
ADediting_908299chr2_96269876_+SINEAluName=AluY
ADediting_908300chr2_96269881_+SINEAluName=AluY
ADediting_908301chr2_96269892_+SINEAluName=AluY
ADediting_908302chr2_96269905_+SINEAluName=AluY
ADediting_908303chr2_96269906_+SINEAluName=AluY
ADediting_908304chr2_96269907_+SINEAluName=AluY
ADediting_908305chr2_96269919_+SINEAluName=AluY
ADediting_908306chr2_96269921_+SINEAluName=AluY
ADediting_908307chr2_96269925_+SINEAluName=AluY
ADediting_908308chr2_96270229_+SINEAluName=AluSg
ADediting_908309chr2_96270251_+SINEAluName=AluSg
ADediting_908310chr2_96270252_+SINEAluName=AluSg
ADediting_908311chr2_96270257_+SINEAluName=AluSg
ADediting_908312chr2_96270258_+SINEAluName=AluSg
ADediting_908313chr2_96270268_+SINEAluName=AluSg
ADediting_908314chr2_96270273_+SINEAluName=AluSg
ADediting_908315chr2_96270274_+SINEAluName=AluSg
ADediting_908316chr2_96270279_+SINEAluName=AluSg
ADediting_908317chr2_96270283_+SINEAluName=AluSg
ADediting_908318chr2_96270290_+SINEAluName=AluSg
ADediting_908319chr2_96270295_+SINEAluName=AluSg
ADediting_908320chr2_96270303_+SINEAluName=AluSg
ADediting_908321chr2_96270304_+SINEAluName=AluSg
ADediting_908322chr2_96270309_+SINEAluName=AluSg
ADediting_908323chr2_96270318_+SINEAluName=AluSg
ADediting_908324chr2_96270319_+SINEAluName=AluSg
ADediting_908325chr2_96270321_+SINEAluName=AluSg
ADediting_908326chr2_96270329_+SINEAluName=AluSg
ADediting_908327chr2_96270340_+SINEAluName=AluSg
ADediting_908328chr2_96270345_+SINEAluName=AluSg
ADediting_908329chr2_96270346_+SINEAluName=AluSg
ADediting_908330chr2_96270353_+SINEAluName=AluSg
ADediting_908331chr2_96270354_+SINEAluName=AluSg
ADediting_908332chr2_96270358_+SINEAluName=AluSg
ADediting_908333chr2_96270374_+SINEAluName=AluSg
ADediting_908334chr2_96270378_+SINEAluName=AluSg
ADediting_908335chr2_96270382_+SINEAluName=AluSg
ADediting_908336chr2_96270383_+SINEAluName=AluSg
ADediting_908337chr2_96270388_+SINEAluName=AluSg
ADediting_908338chr2_96270392_+SINEAluName=AluSg
ADediting_908339chr2_96270396_+SINEAluName=AluSg
ADediting_908340chr2_96270423_+SINEAluName=AluSg
ADediting_908341chr2_96270447_+SINEAluName=AluSg
ADediting_908342chr2_96270452_+SINEAluName=AluSg
ADediting_908343chr2_96270488_+SINEAluName=AluSg
ADediting_908344chr2_96270554_+SINEAluName=AluSz
ADediting_908345chr2_96270555_+SINEAluName=AluSz
ADediting_908346chr2_96270581_+SINEAluName=AluSz
ADediting_908347chr2_96270609_+SINEAluName=AluSz
ADediting_908348chr2_96270623_+SINEAluName=AluSz
ADediting_908349chr2_96270624_+SINEAluName=AluSz
ADediting_908350chr2_96270631_+SINEAluName=AluSz
ADediting_908351chr2_96270634_+SINEAluName=AluSz
ADediting_908352chr2_96270645_+SINEAluName=AluSz
ADediting_908353chr2_96270651_+SINEAluName=AluSz
ADediting_908354chr2_96270660_+SINEAluName=AluSz
ADediting_908355chr2_96270663_+SINEAluName=AluSz
ADediting_908356chr2_96270689_+SINEAluName=AluSz
ADediting_908357chr2_96270703_+SINEAluName=AluSz
ADediting_908358chr2_96270716_+SINEAluName=AluSz
ADediting_908359chr2_96270722_+SINEAluName=AluSz
ADediting_908360chr2_96270731_+SINEAluName=AluSz
ADediting_908361chr2_96270759_+SINEAluName=AluSz
ADediting_908362chr2_96270760_+SINEAluName=AluSz
ADediting_908363chr2_96270790_+SINEAluName=AluSz
ADediting_908364chr2_96270797_+SINEAluName=AluSz
ADediting_908365chr2_96270798_+SINEAluName=AluSz
ADediting_1564954chr2_96268168_+SINEAluName=AluSx
ADediting_1564955chr2_96272717_+SINEAluName=AluSp
ADediting_1639728chr2_96273577_+SINEAluName=AluSx4
ADediting_1639729chr2_96273584_+SINEAluName=AluSx4

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RNA A-to-I editing events in the alternative splicing sites for CIAO1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CIAO1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
Soverview
Soverview
Soverview
ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for CIAO1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CIAO1

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1564955chr2_96272717_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-1976chr296272713962727208mer-1a9627270096272720149-24.39
ADediting_1564955chr2_96272717_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-6747-3pchr296272711962727188mer-1a9627269696272718149-23.68
ADediting_1639729chr2_96273584_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-4437chr296273580962735867mer-m89627356796273587153-20.38

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1564955chr2_96272717_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-3152-5pchr296272710962727167mer-m89627269596272717145-14.62
ADediting_1564955chr2_96272717_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-4753-3pchr296272715962727217mer-1a9627270096272721146-27.76
ADediting_1639728chr2_96273577_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-26a-1-3pchr296273571962735777mer-m89627356096273578143-11.37
ADediting_1639728chr2_96273577_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-26a-2-3pchr296273571962735777mer-m89627355996273578142-13.57
ADediting_1639729chr2_96273584_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-498-5pchr296273577962735837mer-m89627356296273584142-10.03

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1535953chr14_101045971_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-381-3pchr296271584962715907mer-m89627157096271591158-15.45
ADediting_1535954chr14_101045974_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-381-3pchr296272003962720097mer-m89627198996272010145-13.91
ADediting_1631458chr19_40282624_-ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-641chr296272480962724867mer-m89627246696272487150-17.2
ADediting_843620chr2_207754818_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-4775chr296272052962720587mer-m89627203796272059158-8.57
ADediting_843620chr2_207754818_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-4775chr296273250962732567mer-m89627323496273257144-11.53
ADediting_843620chr2_207754818_+ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-4775chr296273682962736887mer-m89627366896273689162-5.96

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337758chr7_5495892_-ENSG00000144021.3ENST00000488633.2CIAO1-203hsa-miR-589-5pchr296272352962723587mer-m89627233996272359155-21.55

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CIAO1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000488633.2protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1564955ENST00000488633.2chr2_96272717_+2512-1369.70-1365.90-1372.50
ADediting_1639728ENST00000488633.2chr2_96273577_+3372-1366.10-1365.90-1372.50
ADediting_1639729ENST00000488633.2chr2_96273584_+3379-1368.20-1365.90-1372.50

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CIAO1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_908284chr2_96269671_+4.89387510180349e-080.3037082279518165.68497212609226e-130.3942681627377670.0008359410792724450.188787693555516
DLPFCADediting_908286chr2_96269717_+0.001611694969385610.1784043493511844.39740082785088e-090.3255030416975430.0100316434666590.146040346164156
DLPFCADediting_908288chr2_96269728_+8.16799581062945e-050.2218457694383328.80908095499798e-110.357578862379670.04273443019354180.11516794188676
DLPFCADediting_908301chr2_96269892_+4.37199536442183e-090.3255534023373441.05307148031913e-080.3178049825160840.0002811394784008060.204923033226211
DLPFCADediting_908303chr2_96269906_+1.01967897089717e-080.3180929227611421.13071229486526e-090.337063879619710.02091001166301860.13113955363419
DLPFCADediting_908304chr2_96269907_+1.75176767831615e-110.3698395258983131.48242865412995e-130.4033211436227260.005606277726451660.156980899998592
DLPFCADediting_908305chr2_96269919_+4.53626749648965e-100.3445773272508651.14362927885055e-150.433972346655470.01587958777813740.136881378100564
CERADediting_908305chr2_96269919_+1.53302133609578e-060.3807774377425631.19563898051898e-070.4159917737004970.2724691894168880.0901735114068775
TCXADediting_908305chr2_96269919_+0.6133203303988450.04159087201976722.73676449304113e-050.3353032910533880.942392642897386-0.00594996800980957
DLPFCADediting_908307chr2_96269925_+9.9587723438977e-100.3381205836966621.60206581766374e-170.458524595631290.02425833446767810.127953019187677
CERADediting_908307chr2_96269925_+0.0002862567924612970.292134516998230.0001107857706762780.3103948783487730.2970783449697390.0856978345706191
DLPFCADediting_908309chr2_96270251_+1.62108616389377e-050.2422027110178444.92323779315097e-100.3439120222214270.01672380662508310.135816000086588
DLPFCADediting_908310chr2_96270252_+3.84580967209752e-060.2589304576899498.81937938661402e-100.3391279903302930.01231640348941230.142010337885653
DLPFCADediting_908312chr2_96270258_+4.58023739158717e-050.2293389595246055.66518473012329e-090.323292150133710.003434621318555480.165699047333229
DLPFCADediting_908323chr2_96270318_+0.3034548588238490.05863283909003270.616993093023627-0.02851411856453311.15236000812041e-100.355488159116142
DLPFCADediting_908325chr2_96270321_+0.4284727295822920.0451310626036410.422273458406403-0.04573890280832931.37882991431071e-160.446389811839534

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.06815999672006e-500.7180815908813848.83079834447988e-350.6234399054770463.65836406164236e-310.595727002753331
AC6.48237764759576e-1150.9365668598131046.45711078915843e-730.8557152941666594.1417858084474e-140.453895273074762
PCC3.48271291034195e-750.9122577685921871.53155031906356e-700.9011881214892130.0003193385160057260.257699900942821
CER1.0990273658822e-420.8481947720149254.84299685431334e-270.7377946028900350.002437518494265780.245729063747033
TCX1.9755070257601e-570.9069266287868638.46405677125423e-210.6688547694349540.00195791868978370.250874263280049
FP4.38019413026358e-310.7314920676859011.78979066469189e-430.8144920327963870.003786207183150320.215977086934973
IFG3.00433864412009e-080.8623131595560584.7284456918132e-080.856395210503160.4011230852468570.175603049376015
PG3.04732533128981e-640.8887596824287863.7872272538051e-400.7851789556335390.7546561925543510.0230664822527617
STG1.36893240980669e-260.8674992783915392.71223128998323e-230.8381315225380160.6603636659589860.0486441623828318

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Relation with AD stages for CIAO1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX0.0004670210084941750.333998185374801

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RelatedDrugs for CIAO1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CIAO1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource