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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for PGAP3

check button Gene summary
Gene informationGene symbol

PGAP3

Gene ID

93210

Gene namepost-GPI attachment to proteins phospholipase 3
SynonymsAGLA546|CAB2|PERLD1|PP1498|hCOS16
Cytomap

17q12

Type of geneprotein-coding
Descriptionpost-GPI attachment to proteins factor 3COS16 homologgene coamplified with ERBB2 proteinper1-like domain containing 1post-GPI attachment to proteins 3
Modification date20200327
UniProtAcc

Q96FM1,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for PGAP3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_617865(39674483, -), ADediting_617866(39675216, -), ADediting_617867(39675844, -), ADediting_617868(39678977, -), ADediting_617869(39679012, -), ADediting_617870(39679022, -), ADediting_617871(39679023, -), ADediting_617872(39679027, -), ADediting_617873(39679031, -), ADediting_617874(39679040, -), ADediting_617875(39679044, -), ADediting_617876(39679051, -), ADediting_617877(39679052, -), ADediting_617878(39679074, -), ADediting_617879(39679083, -), ADediting_617880(39679084, -), ADediting_617881(39679110, -), ADediting_617882(39679114, -), ADediting_617883(39679119, -), ADediting_617884(39679124, -), ADediting_617885(39679125, -), ADediting_617886(39679128, -), ADediting_617887(39679139, -), ADediting_617888(39679149, -), ADediting_617889(39679150, -), ADediting_617890(39679159, -), ADediting_617891(39679164, -), ADediting_617892(39679165, -), ADediting_617893(39679172, -), ADediting_617894(39679191, -), ADediting_617895(39679201, -), ADediting_617896(39679217, -), ADediting_617897(39680956, -), ADediting_617898(39680961, -), ADediting_617899(39680966, -), ADediting_617900(39680988, -), ADediting_617901(39680991, -), ADediting_617902(39681001, -), ADediting_617903(39681009, -), ADediting_617904(39681023, -), ADediting_617905(39681028, -), ADediting_617906(39681045, -), ADediting_617907(39681059, -), ADediting_617908(39681061, -), ADediting_617909(39681067, -), ADediting_617910(39681069, -), ADediting_617911(39681115, -), ADediting_617912(39681122, -), ADediting_617913(39681130, -), ADediting_617914(39681145, -), ADediting_617915(39681155, -), ADediting_617916(39681535, -), ADediting_617917(39681536, -), ADediting_617918(39681571, -), ADediting_617919(39681581, -), ADediting_617920(39681605, -), ADediting_617921(39681611, -), ADediting_617922(39681616, -), ADediting_617923(39681620, -), ADediting_617924(39681647, -), ADediting_617925(39681663, -), ADediting_617926(39681665, -), ADediting_617927(39681673, -), ADediting_617928(39681686, -), ADediting_617929(39681701, -), ADediting_617930(39681705, -), ADediting_617931(39681706, -), ADediting_617932(39681709, -), ADediting_617933(39681711, -), ADediting_617934(39681712, -), ADediting_617935(39681721, -), ADediting_617936(39681727, -), ADediting_617937(39681735, -), ADediting_617938(39681759, -), ADediting_617939(39681780, -), ADediting_617940(39681958, -), ADediting_617941(39681964, -), ADediting_617942(39681976, -), ADediting_617943(39681977, -), ADediting_617944(39682022, -), ADediting_617945(39682027, -), ADediting_617946(39682031, -), ADediting_617947(39682036, -), ADediting_617948(39682053, -), ADediting_617949(39682102, -), ADediting_617950(39682104, -), ADediting_617951(39682107, -), ADediting_617952(39682114, -), ADediting_617953(39682139, -), ADediting_617954(39682163, -), ADediting_617955(39682179, -), ADediting_617956(39682816, -), ADediting_617957(39682822, -), ADediting_617958(39682834, -), ADediting_617959(39682835, -), ADediting_617960(39682911, -), ADediting_617961(39682914, -), ADediting_617962(39682953, -), ADediting_617963(39682955, -), ADediting_617964(39682965, -), ADediting_617965(39682990, -), ADediting_617966(39682994, -), ADediting_617967(39682995, -), ADediting_617968(39683013, -), ADediting_617969(39683880, -), ADediting_617970(39683959, -), ADediting_617971(39683962, -), ADediting_617972(39684012, -), ADediting_617973(39684037, -), ADediting_617974(39684038, -), ADediting_617975(39684041, -), ADediting_617976(39684061, -), ADediting_617977(39684067, -), ADediting_617978(39684111, -), ADediting_617979(39684119, -), ADediting_617980(39685435, -), ADediting_617981(39686515, -), ADediting_1546276(39679007, -), ADediting_1546277(39679078, -), ADediting_1546278(39679218, -), ADediting_1546279(39680940, -), ADediting_1546280(39681041, -), ADediting_1546281(39681133, -), ADediting_1546282(39681598, -), ADediting_1546283(39681614, -), ADediting_1546284(39681655, -), ADediting_1546285(39681758, -), ADediting_1546286(39681772, -), ADediting_1546287(39681775, -), ADediting_1546288(39682039, -), ADediting_1546289(39682056, -), ADediting_1546290(39682836, -), ADediting_1546291(39683920, -), ADediting_1546292(39684062, -), ADediting_1546293(39684123, -),

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RNA editing positional annotations for PGAP3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_617865chr17_39674483_-intronic
ADediting_617866chr17_39675216_-intronic
ADediting_617867chr17_39675844_-intronic
ADediting_617868chr17_39678977_-intronic
ADediting_617869chr17_39679012_-intronic
ADediting_617870chr17_39679022_-intronic
ADediting_617871chr17_39679023_-intronic
ADediting_617872chr17_39679027_-intronic
ADediting_617873chr17_39679031_-intronic
ADediting_617874chr17_39679040_-intronic
ADediting_617875chr17_39679044_-intronic
ADediting_617876chr17_39679051_-intronic
ADediting_617877chr17_39679052_-intronic
ADediting_617878chr17_39679074_-intronic
ADediting_617879chr17_39679083_-intronic
ADediting_617880chr17_39679084_-intronic
ADediting_617881chr17_39679110_-intronic
ADediting_617882chr17_39679114_-intronic
ADediting_617883chr17_39679119_-intronic
ADediting_617884chr17_39679124_-intronic
ADediting_617885chr17_39679125_-intronic
ADediting_617886chr17_39679128_-intronic
ADediting_617887chr17_39679139_-intronic
ADediting_617888chr17_39679149_-intronic
ADediting_617889chr17_39679150_-intronic
ADediting_617890chr17_39679159_-intronic
ADediting_617891chr17_39679164_-intronic
ADediting_617892chr17_39679165_-intronic
ADediting_617893chr17_39679172_-intronic
ADediting_617894chr17_39679191_-intronic
ADediting_617895chr17_39679201_-intronic
ADediting_617896chr17_39679217_-intronic
ADediting_617897chr17_39680956_-intronic
ADediting_617898chr17_39680961_-intronic
ADediting_617899chr17_39680966_-intronic
ADediting_617900chr17_39680988_-intronic
ADediting_617901chr17_39680991_-intronic
ADediting_617902chr17_39681001_-intronic
ADediting_617903chr17_39681009_-intronic
ADediting_617904chr17_39681023_-intronic
ADediting_617905chr17_39681028_-intronic
ADediting_617906chr17_39681045_-intronic
ADediting_617907chr17_39681059_-intronic
ADediting_617908chr17_39681061_-intronic
ADediting_617909chr17_39681067_-intronic
ADediting_617910chr17_39681069_-intronic
ADediting_617911chr17_39681115_-intronic
ADediting_617912chr17_39681122_-intronic
ADediting_617913chr17_39681130_-intronic
ADediting_617914chr17_39681145_-intronic
ADediting_617915chr17_39681155_-intronic
ADediting_617916chr17_39681535_-intronic
ADediting_617917chr17_39681536_-intronic
ADediting_617918chr17_39681571_-intronic
ADediting_617919chr17_39681581_-intronic
ADediting_617920chr17_39681605_-intronic
ADediting_617921chr17_39681611_-intronic
ADediting_617922chr17_39681616_-intronic
ADediting_617923chr17_39681620_-intronic
ADediting_617924chr17_39681647_-intronic
ADediting_617925chr17_39681663_-intronic
ADediting_617926chr17_39681665_-intronic
ADediting_617927chr17_39681673_-intronic
ADediting_617928chr17_39681686_-intronic
ADediting_617929chr17_39681701_-intronic
ADediting_617930chr17_39681705_-intronic
ADediting_617931chr17_39681706_-intronic
ADediting_617932chr17_39681709_-intronic
ADediting_617933chr17_39681711_-intronic
ADediting_617934chr17_39681712_-intronic
ADediting_617935chr17_39681721_-intronic
ADediting_617936chr17_39681727_-intronic
ADediting_617937chr17_39681735_-intronic
ADediting_617938chr17_39681759_-intronic
ADediting_617939chr17_39681780_-intronic
ADediting_617940chr17_39681958_-intronic
ADediting_617941chr17_39681964_-intronic
ADediting_617942chr17_39681976_-intronic
ADediting_617943chr17_39681977_-intronic
ADediting_617944chr17_39682022_-intronic
ADediting_617945chr17_39682027_-intronic
ADediting_617946chr17_39682031_-intronic
ADediting_617947chr17_39682036_-intronic
ADediting_617948chr17_39682053_-intronic
ADediting_617949chr17_39682102_-intronic
ADediting_617950chr17_39682104_-intronic
ADediting_617951chr17_39682107_-intronic
ADediting_617952chr17_39682114_-intronic
ADediting_617953chr17_39682139_-intronic
ADediting_617954chr17_39682163_-intronic
ADediting_617955chr17_39682179_-intronic
ADediting_617956chr17_39682816_-intronic
ADediting_617957chr17_39682822_-intronic
ADediting_617958chr17_39682834_-intronic
ADediting_617959chr17_39682835_-intronic
ADediting_617960chr17_39682911_-intronic
ADediting_617961chr17_39682914_-intronic
ADediting_617962chr17_39682953_-intronic
ADediting_617963chr17_39682955_-intronic
ADediting_617964chr17_39682965_-intronic
ADediting_617965chr17_39682990_-intronic
ADediting_617966chr17_39682994_-intronic
ADediting_617967chr17_39682995_-intronic
ADediting_617968chr17_39683013_-intronic
ADediting_617969chr17_39683880_-intronic
ADediting_617970chr17_39683959_-intronic
ADediting_617971chr17_39683962_-intronic
ADediting_617972chr17_39684012_-intronic
ADediting_617973chr17_39684037_-intronic
ADediting_617974chr17_39684038_-intronic
ADediting_617975chr17_39684041_-intronic
ADediting_617976chr17_39684061_-intronic
ADediting_617977chr17_39684067_-intronic
ADediting_617978chr17_39684111_-intronic
ADediting_617979chr17_39684119_-intronic
ADediting_617980chr17_39685435_-intronic
ADediting_617981chr17_39686515_-intronic
ADediting_1546276chr17_39679007_-intronic
ADediting_1546277chr17_39679078_-intronic
ADediting_1546278chr17_39679218_-intronic
ADediting_1546279chr17_39680940_-intronic
ADediting_1546280chr17_39681041_-intronic
ADediting_1546281chr17_39681133_-intronic
ADediting_1546282chr17_39681598_-intronic
ADediting_1546283chr17_39681614_-intronic
ADediting_1546284chr17_39681655_-intronic
ADediting_1546285chr17_39681758_-intronic
ADediting_1546286chr17_39681772_-intronic
ADediting_1546287chr17_39681775_-intronic
ADediting_1546288chr17_39682039_-intronic
ADediting_1546289chr17_39682056_-intronic
ADediting_1546290chr17_39682836_-intronic
ADediting_1546291chr17_39683920_-intronic
ADediting_1546292chr17_39684062_-intronic
ADediting_1546293chr17_39684123_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_617865chr17_39674483_-SINEMIRName=MIRb
ADediting_617868chr17_39678977_-SINEAluName=AluSx1
ADediting_617869chr17_39679012_-SINEAluName=AluSx1
ADediting_617870chr17_39679022_-SINEAluName=AluSx1
ADediting_617871chr17_39679023_-SINEAluName=AluSx1
ADediting_617872chr17_39679027_-SINEAluName=AluSx1
ADediting_617873chr17_39679031_-SINEAluName=AluSx1
ADediting_617874chr17_39679040_-SINEAluName=AluSx1
ADediting_617875chr17_39679044_-SINEAluName=AluSx1
ADediting_617876chr17_39679051_-SINEAluName=AluSx1
ADediting_617877chr17_39679052_-SINEAluName=AluSx1
ADediting_617878chr17_39679074_-SINEAluName=AluSx1
ADediting_617879chr17_39679083_-SINEAluName=AluSx1
ADediting_617880chr17_39679084_-SINEAluName=AluSx1
ADediting_617881chr17_39679110_-SINEAluName=AluSx1
ADediting_617882chr17_39679114_-SINEAluName=AluSx1
ADediting_617883chr17_39679119_-SINEAluName=AluSx1
ADediting_617884chr17_39679124_-SINEAluName=AluSx1
ADediting_617885chr17_39679125_-SINEAluName=AluSx1
ADediting_617886chr17_39679128_-SINEAluName=AluSx1
ADediting_617887chr17_39679139_-SINEAluName=AluSx1
ADediting_617888chr17_39679149_-SINEAluName=AluSx1
ADediting_617889chr17_39679150_-SINEAluName=AluSx1
ADediting_617890chr17_39679159_-SINEAluName=AluSx1
ADediting_617891chr17_39679164_-SINEAluName=AluSx1
ADediting_617892chr17_39679165_-SINEAluName=AluSx1
ADediting_617893chr17_39679172_-SINEAluName=AluSx1
ADediting_617894chr17_39679191_-SINEAluName=AluSx1
ADediting_617895chr17_39679201_-SINEAluName=AluSx1
ADediting_617896chr17_39679217_-SINEAluName=AluSx1
ADediting_617897chr17_39680956_-SINEAluName=AluJb
ADediting_617898chr17_39680961_-SINEAluName=AluJb
ADediting_617899chr17_39680966_-SINEAluName=AluJb
ADediting_617900chr17_39680988_-SINEAluName=AluJb
ADediting_617901chr17_39680991_-SINEAluName=AluJb
ADediting_617902chr17_39681001_-SINEAluName=AluJb
ADediting_617903chr17_39681009_-SINEAluName=AluJb
ADediting_617904chr17_39681023_-SINEAluName=AluJb
ADediting_617905chr17_39681028_-SINEAluName=AluJb
ADediting_617906chr17_39681045_-SINEAluName=AluJb
ADediting_617907chr17_39681059_-SINEAluName=AluJb
ADediting_617908chr17_39681061_-SINEAluName=AluJb
ADediting_617909chr17_39681067_-SINEAluName=AluJb
ADediting_617910chr17_39681069_-SINEAluName=AluJb
ADediting_617911chr17_39681115_-SINEAluName=AluJb
ADediting_617912chr17_39681122_-SINEAluName=AluJb
ADediting_617913chr17_39681130_-SINEAluName=AluJb
ADediting_617914chr17_39681145_-SINEAluName=AluJb
ADediting_617915chr17_39681155_-SINEAluName=AluJb
ADediting_617916chr17_39681535_-SINEAluName=AluSp
ADediting_617917chr17_39681536_-SINEAluName=AluSp
ADediting_617918chr17_39681571_-SINEAluName=AluSp
ADediting_617919chr17_39681581_-SINEAluName=AluSp
ADediting_617920chr17_39681605_-SINEAluName=AluSp
ADediting_617921chr17_39681611_-SINEAluName=AluSp
ADediting_617922chr17_39681616_-SINEAluName=AluSp
ADediting_617923chr17_39681620_-SINEAluName=AluSp
ADediting_617924chr17_39681647_-SINEAluName=AluSp
ADediting_617925chr17_39681663_-SINEAluName=AluSp
ADediting_617926chr17_39681665_-SINEAluName=AluSp
ADediting_617927chr17_39681673_-SINEAluName=AluSp
ADediting_617928chr17_39681686_-SINEAluName=AluSp
ADediting_617929chr17_39681701_-SINEAluName=AluSp
ADediting_617930chr17_39681705_-SINEAluName=AluSp
ADediting_617931chr17_39681706_-SINEAluName=AluSp
ADediting_617932chr17_39681709_-SINEAluName=AluSp
ADediting_617933chr17_39681711_-SINEAluName=AluSp
ADediting_617934chr17_39681712_-SINEAluName=AluSp
ADediting_617935chr17_39681721_-SINEAluName=AluSp
ADediting_617936chr17_39681727_-SINEAluName=AluSp
ADediting_617937chr17_39681735_-SINEAluName=AluSp
ADediting_617938chr17_39681759_-SINEAluName=AluSp
ADediting_617939chr17_39681780_-SINEAluName=AluSp
ADediting_617940chr17_39681958_-SINEAluName=AluY
ADediting_617941chr17_39681964_-SINEAluName=AluY
ADediting_617942chr17_39681976_-SINEAluName=AluY
ADediting_617943chr17_39681977_-SINEAluName=AluY
ADediting_617944chr17_39682022_-SINEAluName=AluY
ADediting_617945chr17_39682027_-SINEAluName=AluY
ADediting_617946chr17_39682031_-SINEAluName=AluY
ADediting_617947chr17_39682036_-SINEAluName=AluY
ADediting_617948chr17_39682053_-SINEAluName=AluY
ADediting_617949chr17_39682102_-SINEAluName=AluY
ADediting_617950chr17_39682104_-SINEAluName=AluY
ADediting_617951chr17_39682107_-SINEAluName=AluY
ADediting_617952chr17_39682114_-SINEAluName=AluY
ADediting_617953chr17_39682139_-SINEAluName=AluY
ADediting_617954chr17_39682163_-SINEAluName=AluY
ADediting_617955chr17_39682179_-SINEAluName=AluY
ADediting_617956chr17_39682816_-SINEAluName=AluSg
ADediting_617957chr17_39682822_-SINEAluName=AluSg
ADediting_617958chr17_39682834_-SINEAluName=AluSg
ADediting_617959chr17_39682835_-SINEAluName=AluSg
ADediting_617960chr17_39682911_-SINEAluName=AluSg
ADediting_617961chr17_39682914_-SINEAluName=AluSg
ADediting_617962chr17_39682953_-SINEAluName=AluSg
ADediting_617963chr17_39682955_-SINEAluName=AluSg
ADediting_617964chr17_39682965_-SINEAluName=AluSg
ADediting_617965chr17_39682990_-SINEAluName=AluSg
ADediting_617966chr17_39682994_-SINEAluName=AluSg
ADediting_617967chr17_39682995_-SINEAluName=AluSg
ADediting_617968chr17_39683013_-SINEAluName=AluSg
ADediting_617969chr17_39683880_-SINEAluName=AluSx
ADediting_617970chr17_39683959_-SINEAluName=AluSx
ADediting_617971chr17_39683962_-SINEAluName=AluSx
ADediting_617972chr17_39684012_-SINEAluName=AluSx
ADediting_617973chr17_39684037_-SINEAluName=AluSx
ADediting_617974chr17_39684038_-SINEAluName=AluSx
ADediting_617975chr17_39684041_-SINEAluName=AluSx
ADediting_617976chr17_39684061_-SINEAluName=AluSx
ADediting_617977chr17_39684067_-SINEAluName=AluSx
ADediting_617978chr17_39684111_-SINEAluName=AluSx
ADediting_617979chr17_39684119_-SINEAluName=AluSx
ADediting_617980chr17_39685435_-SINEAluName=AluSc8
ADediting_617981chr17_39686515_-SINEAluName=AluSp
ADediting_1546276chr17_39679007_-SINEAluName=AluSx1
ADediting_1546277chr17_39679078_-SINEAluName=AluSx1
ADediting_1546278chr17_39679218_-SINEAluName=AluSx1
ADediting_1546279chr17_39680940_-SINEAluName=AluJb
ADediting_1546280chr17_39681041_-SINEAluName=AluJb
ADediting_1546281chr17_39681133_-SINEAluName=AluJb
ADediting_1546282chr17_39681598_-SINEAluName=AluSp
ADediting_1546283chr17_39681614_-SINEAluName=AluSp
ADediting_1546284chr17_39681655_-SINEAluName=AluSp
ADediting_1546285chr17_39681758_-SINEAluName=AluSp
ADediting_1546286chr17_39681772_-SINEAluName=AluSp
ADediting_1546287chr17_39681775_-SINEAluName=AluSp
ADediting_1546288chr17_39682039_-SINEAluName=AluY
ADediting_1546289chr17_39682056_-SINEAluName=AluY
ADediting_1546290chr17_39682836_-SINEAluName=AluSg
ADediting_1546291chr17_39683920_-SINEAluName=AluSx
ADediting_1546292chr17_39684062_-SINEAluName=AluSx
ADediting_1546293chr17_39684123_-SINEAluName=AluSx

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RNA A-to-I editing events in the alternative splicing sites for PGAP3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PGAP3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for PGAP3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for PGAP3


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000161395.14ENST00000300658.9PGAP3-201hsa-miR-589-3pchr1739671277396712837mer-m83967127639671300161-22.53
ADediting_1337757chr7_5495852_-ENSG00000161395.14ENST00000378011.8PGAP3-203hsa-miR-589-3pchr1739671277396712837mer-m83967127639671300161-22.53
ADediting_1337757chr7_5495852_-ENSG00000161395.14ENST00000579146.5PGAP3-206hsa-miR-589-3pchr1739671277396712837mer-m83967127639671300161-22.53
ADediting_1337757chr7_5495852_-ENSG00000161395.14ENST00000619169.4PGAP3-211hsa-miR-589-3pchr1739671277396712837mer-m83967127639671300161-22.53
ADediting_1337758chr7_5495892_-ENSG00000161395.14ENST00000300658.9PGAP3-201hsa-miR-589-5pchr1739672223396722308mer-1a3967222339672243141-16.2
ADediting_1337758chr7_5495892_-ENSG00000161395.14ENST00000378011.8PGAP3-203hsa-miR-589-5pchr1739672223396722308mer-1a3967222339672243141-16.2
ADediting_1337758chr7_5495892_-ENSG00000161395.14ENST00000579146.5PGAP3-206hsa-miR-589-5pchr1739672223396722308mer-1a3967222339672243141-16.2

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for PGAP3

check button - RNA A-to-I editing in mRNA.
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ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for PGAP3

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_617870chr17_39679022_-0.02945756835585790.1236872501799010.8760440570547620.008895168495507746.22542612591619e-110.360258377631469
DLPFCADediting_617871chr17_39679023_-0.02375071655790510.1284106355780590.794422820617790.01485868615689091.98332078754474e-080.312085189754239
DLPFCADediting_617874chr17_39679040_-0.02470441617739380.1275576466803560.9174974010729120.005907137130544381.05916310221905e-090.337608368370845
DLPFCADediting_617879chr17_39679083_-0.0006625545260879290.1923380403623040.2096287043104490.07145330009756881.11281807023944e-110.373192366930903
DLPFCADediting_617899chr17_39680966_-0.1684644651262550.07841341326849610.433299649631225-0.04466130049781013.21283352839139e-110.365296211209333
DLPFCADediting_617900chr17_39680988_-0.01272664746340730.1413577785444460.98478243491858-0.001087698332652011.06416755780969e-110.373520617244654
DLPFCADediting_617966chr17_39682994_-0.009946939617987360.1462048478019230.6835532151776150.02324198302394581.71203884620529e-140.417308591243212
DLPFCADediting_617968chr17_39683013_-0.0003946710701865720.2000343815179980.04656362208787820.1131323679756262.03921361741912e-120.385401259579293

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.36810600688702e-190.4809702241200512.22165164614774e-240.5352700427368711.26719059315065e-220.517386900153605
AC1.93217162474046e-640.8286671466667471.47921436611452e-460.7507498311085011.45406528437349e-160.490851622777342
PCC1.04268478161476e-310.719182959269482.88879116257659e-270.6799588733032790.001762025010175490.22488003988185
CER0.00187306153674408-0.251902206004881.6966759886647e-06-0.3792894252607980.485979616466675-0.0573194530787408
TCX4.20270998715582e-070.3991474291643882.21122111252004e-070.4078681721754430.941885435971929-0.00600244636022282
FP3.23392781688838e-130.5107803931392893.13828066741823e-110.4713114681461020.0002101051981174360.274398782328807
IFG2.99246457406166e-060.7874733340314580.0001434938700260580.688134886123770.7246058968772790.0741616265863803
STG2.21379239437447e-170.7656276777359032.25788011618807e-070.5293223946594890.04321838590552620.221148433910944

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Relation with AD stages for PGAP3

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for PGAP3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PGAP3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
PGAP3C0282577Congenital Disorders of Glycosylation1GENOMICS_ENGLAND
PGAP3C3714756Intellectual Disability1GENOMICS_ENGLAND
PGAP3C3810354HYPERPHOSPHATASIA WITH MENTAL RETARDATION SYNDROME 41UNIPROT