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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for BBIP1 |
 Gene summary |
| Gene information | Gene symbol | BBIP1 | Gene ID | 92482 |
| Gene name | BBSome interacting protein 1 | |
| Synonyms | BBIP10|BBS18|NCRNA00081|bA348N5.3 | |
| Cytomap | 10q25.2 | |
| Type of gene | protein-coding | |
| Description | BBSome-interacting protein 1BBSome-interacting protein of 10 kDaUPF0604 protein | |
| Modification date | 20200313 | |
| UniProtAcc | A8MTZ0, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for BBIP1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_163265(110901119, -), ADediting_163266(110901175, -), ADediting_163267(110901245, -), ADediting_163268(110905307, -), ADediting_163269(110905319, -), ADediting_163270(110905320, -), ADediting_163271(110905341, -), ADediting_163272(110905357, -), ADediting_163273(110905363, -), ADediting_163274(110905366, -), ADediting_163275(110905369, -), ADediting_163276(110905373, -), ADediting_163277(110905378, -), ADediting_163278(110905381, -), ADediting_163279(110905404, -), ADediting_163280(110905438, -), ADediting_163281(110905440, -), ADediting_163282(110905450, -), ADediting_163283(110905499, -), ADediting_163284(110905518, -), ADediting_163285(110906167, -), ADediting_163286(110906196, -), ADediting_163287(110906201, -), ADediting_163288(110906207, -), ADediting_163289(110906211, -), ADediting_163290(110906212, -), ADediting_163291(110906226, -), ADediting_163292(110906227, -), ADediting_163293(110906243, -), ADediting_163294(110906278, -), ADediting_163295(110906279, -), ADediting_163296(110906297, -), ADediting_163297(110906589, -), ADediting_163298(110906590, -), ADediting_163299(110906607, -), ADediting_163300(110906652, -), ADediting_163301(110906688, -), ADediting_163302(110906692, -), ADediting_163303(110906697, -), ADediting_163304(110906698, -), ADediting_163305(110906724, -), ADediting_163306(110906727, -), ADediting_163307(110906728, -), ADediting_163308(110906729, -), ADediting_163309(110906733, -), ADediting_163310(110906736, -), ADediting_163311(110906753, -), ADediting_163312(110906761, -), ADediting_163313(110906763, -), ADediting_163314(110906797, -), ADediting_163315(110906824, -), ADediting_163316(110906832, -), ADediting_163317(110906833, -), ADediting_163318(110906841, -), ADediting_163319(110906849, -), ADediting_163320(110907270, -), ADediting_163321(110907271, -), ADediting_163322(110907285, -), ADediting_163323(110907293, -), ADediting_163324(110907297, -), ADediting_163325(110907298, -), ADediting_163326(110907339, -), ADediting_163327(110907346, -), ADediting_163328(110907386, -), ADediting_163329(110907390, -), ADediting_163330(110907392, -), ADediting_163331(110907398, -), ADediting_163332(110907403, -), ADediting_163333(110907415, -), ADediting_163334(110907429, -), ADediting_163335(110907432, -), ADediting_163336(110907433, -), ADediting_163337(110907479, -), ADediting_163338(110907482, -), ADediting_163339(110909332, -), ADediting_163340(110909359, -), ADediting_163341(110915204, -), ADediting_163342(110915229, -), ADediting_163343(110915259, -), ADediting_163344(110915273, -), ADediting_163345(110915295, -), ADediting_163346(110915780, -), ADediting_163347(110915842, -), ADediting_163348(110915892, -), ADediting_163349(110915898, -), ADediting_163350(110915900, -), ADediting_163351(110915907, -), ADediting_163352(110915950, -), ADediting_163353(110915979, -), ADediting_1522396(110906141, -), ADediting_1522397(110906773, -), ADediting_1522398(110907376, -), ADediting_1522399(110907420, -), ADediting_1522400(110909431, -), ADediting_1522401(110909466, -), ADediting_1522402(110915809, -), ADediting_1522403(110915883, -), ADediting_1522404(110915897, -), ADediting_1522405(110915899, -), ADediting_1522406(110915941, -), ADediting_1603776(110907461, -), |
Top |
RNA editing positional annotations for BBIP1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_163265 | chr10_110901119_- | nonsynonymous SNV | ENST00000398289.2 | c.A116G | p.K39R | . | . | . |
| ADediting_163267 | chr10_110901245_- | synonymous SNV | ENST00000651766.1 | c.A147G | p.V49V | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_163265 | chr10_110901119_- | exonic |
| ADediting_163266 | chr10_110901175_- | UTR3 |
| ADediting_163267 | chr10_110901245_- | exonic |
| ADediting_163268 | chr10_110905307_- | intronic |
| ADediting_163269 | chr10_110905319_- | intronic |
| ADediting_163270 | chr10_110905320_- | intronic |
| ADediting_163271 | chr10_110905341_- | intronic |
| ADediting_163272 | chr10_110905357_- | intronic |
| ADediting_163273 | chr10_110905363_- | intronic |
| ADediting_163274 | chr10_110905366_- | intronic |
| ADediting_163275 | chr10_110905369_- | intronic |
| ADediting_163276 | chr10_110905373_- | intronic |
| ADediting_163277 | chr10_110905378_- | intronic |
| ADediting_163278 | chr10_110905381_- | intronic |
| ADediting_163279 | chr10_110905404_- | intronic |
| ADediting_163280 | chr10_110905438_- | intronic |
| ADediting_163281 | chr10_110905440_- | intronic |
| ADediting_163282 | chr10_110905450_- | intronic |
| ADediting_163283 | chr10_110905499_- | intronic |
| ADediting_163284 | chr10_110905518_- | intronic |
| ADediting_163285 | chr10_110906167_- | intronic |
| ADediting_163286 | chr10_110906196_- | intronic |
| ADediting_163287 | chr10_110906201_- | intronic |
| ADediting_163288 | chr10_110906207_- | intronic |
| ADediting_163289 | chr10_110906211_- | intronic |
| ADediting_163290 | chr10_110906212_- | intronic |
| ADediting_163291 | chr10_110906226_- | intronic |
| ADediting_163292 | chr10_110906227_- | intronic |
| ADediting_163293 | chr10_110906243_- | intronic |
| ADediting_163294 | chr10_110906278_- | intronic |
| ADediting_163295 | chr10_110906279_- | intronic |
| ADediting_163296 | chr10_110906297_- | intronic |
| ADediting_163297 | chr10_110906589_- | intronic |
| ADediting_163298 | chr10_110906590_- | intronic |
| ADediting_163299 | chr10_110906607_- | intronic |
| ADediting_163300 | chr10_110906652_- | intronic |
| ADediting_163301 | chr10_110906688_- | intronic |
| ADediting_163302 | chr10_110906692_- | intronic |
| ADediting_163303 | chr10_110906697_- | intronic |
| ADediting_163304 | chr10_110906698_- | intronic |
| ADediting_163305 | chr10_110906724_- | intronic |
| ADediting_163306 | chr10_110906727_- | intronic |
| ADediting_163307 | chr10_110906728_- | intronic |
| ADediting_163308 | chr10_110906729_- | intronic |
| ADediting_163309 | chr10_110906733_- | intronic |
| ADediting_163310 | chr10_110906736_- | intronic |
| ADediting_163311 | chr10_110906753_- | intronic |
| ADediting_163312 | chr10_110906761_- | intronic |
| ADediting_163313 | chr10_110906763_- | intronic |
| ADediting_163314 | chr10_110906797_- | intronic |
| ADediting_163315 | chr10_110906824_- | intronic |
| ADediting_163316 | chr10_110906832_- | intronic |
| ADediting_163317 | chr10_110906833_- | intronic |
| ADediting_163318 | chr10_110906841_- | intronic |
| ADediting_163319 | chr10_110906849_- | intronic |
| ADediting_163320 | chr10_110907270_- | intronic |
| ADediting_163321 | chr10_110907271_- | intronic |
| ADediting_163322 | chr10_110907285_- | intronic |
| ADediting_163323 | chr10_110907293_- | intronic |
| ADediting_163324 | chr10_110907297_- | intronic |
| ADediting_163325 | chr10_110907298_- | intronic |
| ADediting_163326 | chr10_110907339_- | intronic |
| ADediting_163327 | chr10_110907346_- | intronic |
| ADediting_163328 | chr10_110907386_- | intronic |
| ADediting_163329 | chr10_110907390_- | intronic |
| ADediting_163330 | chr10_110907392_- | intronic |
| ADediting_163331 | chr10_110907398_- | intronic |
| ADediting_163332 | chr10_110907403_- | intronic |
| ADediting_163333 | chr10_110907415_- | intronic |
| ADediting_163334 | chr10_110907429_- | intronic |
| ADediting_163335 | chr10_110907432_- | intronic |
| ADediting_163336 | chr10_110907433_- | intronic |
| ADediting_163337 | chr10_110907479_- | intronic |
| ADediting_163338 | chr10_110907482_- | intronic |
| ADediting_163339 | chr10_110909332_- | intronic |
| ADediting_163340 | chr10_110909359_- | intronic |
| ADediting_163341 | chr10_110915204_- | intronic |
| ADediting_163342 | chr10_110915229_- | intronic |
| ADediting_163343 | chr10_110915259_- | intronic |
| ADediting_163344 | chr10_110915273_- | intronic |
| ADediting_163345 | chr10_110915295_- | intronic |
| ADediting_163346 | chr10_110915780_- | intronic |
| ADediting_163347 | chr10_110915842_- | intronic |
| ADediting_163348 | chr10_110915892_- | intronic |
| ADediting_163349 | chr10_110915898_- | intronic |
| ADediting_163350 | chr10_110915900_- | intronic |
| ADediting_163351 | chr10_110915907_- | intronic |
| ADediting_163352 | chr10_110915950_- | intronic |
| ADediting_163353 | chr10_110915979_- | intronic |
| ADediting_1522396 | chr10_110906141_- | intronic |
| ADediting_1522397 | chr10_110906773_- | intronic |
| ADediting_1522398 | chr10_110907376_- | intronic |
| ADediting_1522399 | chr10_110907420_- | intronic |
| ADediting_1522400 | chr10_110909431_- | intronic |
| ADediting_1522401 | chr10_110909466_- | intronic |
| ADediting_1522402 | chr10_110915809_- | intronic |
| ADediting_1522403 | chr10_110915883_- | intronic |
| ADediting_1522404 | chr10_110915897_- | intronic |
| ADediting_1522405 | chr10_110915899_- | intronic |
| ADediting_1522406 | chr10_110915941_- | intronic |
| ADediting_1603776 | chr10_110907461_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_163265 | chr10_110901119_- | SINE | Alu | Name=AluJo |
| ADediting_163266 | chr10_110901175_- | SINE | Alu | Name=AluJo |
| ADediting_163267 | chr10_110901245_- | SINE | Alu | Name=AluJo |
| ADediting_163268 | chr10_110905307_- | SINE | Alu | Name=AluY |
| ADediting_163269 | chr10_110905319_- | SINE | Alu | Name=AluY |
| ADediting_163270 | chr10_110905320_- | SINE | Alu | Name=AluY |
| ADediting_163271 | chr10_110905341_- | SINE | Alu | Name=AluY |
| ADediting_163272 | chr10_110905357_- | SINE | Alu | Name=AluY |
| ADediting_163273 | chr10_110905363_- | SINE | Alu | Name=AluY |
| ADediting_163274 | chr10_110905366_- | SINE | Alu | Name=AluY |
| ADediting_163275 | chr10_110905369_- | SINE | Alu | Name=AluY |
| ADediting_163276 | chr10_110905373_- | SINE | Alu | Name=AluY |
| ADediting_163277 | chr10_110905378_- | SINE | Alu | Name=AluY |
| ADediting_163278 | chr10_110905381_- | SINE | Alu | Name=AluY |
| ADediting_163279 | chr10_110905404_- | SINE | Alu | Name=AluY |
| ADediting_163280 | chr10_110905438_- | SINE | Alu | Name=AluY |
| ADediting_163281 | chr10_110905440_- | SINE | Alu | Name=AluY |
| ADediting_163282 | chr10_110905450_- | SINE | Alu | Name=AluY |
| ADediting_163283 | chr10_110905499_- | SINE | Alu | Name=AluY |
| ADediting_163284 | chr10_110905518_- | SINE | Alu | Name=AluY |
| ADediting_163285 | chr10_110906167_- | SINE | Alu | Name=AluY |
| ADediting_163286 | chr10_110906196_- | SINE | Alu | Name=AluY |
| ADediting_163287 | chr10_110906201_- | SINE | Alu | Name=AluY |
| ADediting_163288 | chr10_110906207_- | SINE | Alu | Name=AluY |
| ADediting_163289 | chr10_110906211_- | SINE | Alu | Name=AluY |
| ADediting_163290 | chr10_110906212_- | SINE | Alu | Name=AluY |
| ADediting_163291 | chr10_110906226_- | SINE | Alu | Name=AluY |
| ADediting_163292 | chr10_110906227_- | SINE | Alu | Name=AluY |
| ADediting_163293 | chr10_110906243_- | SINE | Alu | Name=AluY |
| ADediting_163294 | chr10_110906278_- | SINE | Alu | Name=AluY |
| ADediting_163295 | chr10_110906279_- | SINE | Alu | Name=AluY |
| ADediting_163296 | chr10_110906297_- | SINE | Alu | Name=AluY |
| ADediting_163297 | chr10_110906589_- | SINE | Alu | Name=AluSz |
| ADediting_163298 | chr10_110906590_- | SINE | Alu | Name=AluSz |
| ADediting_163299 | chr10_110906607_- | SINE | Alu | Name=AluSz |
| ADediting_163300 | chr10_110906652_- | SINE | Alu | Name=AluSz |
| ADediting_163301 | chr10_110906688_- | SINE | Alu | Name=AluSz |
| ADediting_163302 | chr10_110906692_- | SINE | Alu | Name=AluSz |
| ADediting_163303 | chr10_110906697_- | SINE | Alu | Name=AluSz |
| ADediting_163304 | chr10_110906698_- | SINE | Alu | Name=AluSz |
| ADediting_163305 | chr10_110906724_- | SINE | Alu | Name=AluSz |
| ADediting_163306 | chr10_110906727_- | SINE | Alu | Name=AluSz |
| ADediting_163307 | chr10_110906728_- | SINE | Alu | Name=AluSz |
| ADediting_163308 | chr10_110906729_- | SINE | Alu | Name=AluSz |
| ADediting_163309 | chr10_110906733_- | SINE | Alu | Name=AluSz |
| ADediting_163310 | chr10_110906736_- | SINE | Alu | Name=AluSz |
| ADediting_163311 | chr10_110906753_- | SINE | Alu | Name=AluSz |
| ADediting_163312 | chr10_110906761_- | SINE | Alu | Name=AluSz |
| ADediting_163313 | chr10_110906763_- | SINE | Alu | Name=AluSz |
| ADediting_163314 | chr10_110906797_- | SINE | Alu | Name=AluSz |
| ADediting_163315 | chr10_110906824_- | SINE | Alu | Name=AluSz |
| ADediting_163316 | chr10_110906832_- | SINE | Alu | Name=AluSz |
| ADediting_163317 | chr10_110906833_- | SINE | Alu | Name=AluSz |
| ADediting_163318 | chr10_110906841_- | SINE | Alu | Name=AluSz |
| ADediting_163319 | chr10_110906849_- | SINE | Alu | Name=AluSz |
| ADediting_163320 | chr10_110907270_- | SINE | Alu | Name=AluJo |
| ADediting_163321 | chr10_110907271_- | SINE | Alu | Name=AluJo |
| ADediting_163322 | chr10_110907285_- | SINE | Alu | Name=AluJo |
| ADediting_163323 | chr10_110907293_- | SINE | Alu | Name=AluJo |
| ADediting_163324 | chr10_110907297_- | SINE | Alu | Name=AluJo |
| ADediting_163325 | chr10_110907298_- | SINE | Alu | Name=AluJo |
| ADediting_163326 | chr10_110907339_- | SINE | Alu | Name=AluJo |
| ADediting_163327 | chr10_110907346_- | SINE | Alu | Name=AluJo |
| ADediting_163328 | chr10_110907386_- | SINE | Alu | Name=AluJo |
| ADediting_163329 | chr10_110907390_- | SINE | Alu | Name=AluJo |
| ADediting_163330 | chr10_110907392_- | SINE | Alu | Name=AluJo |
| ADediting_163331 | chr10_110907398_- | SINE | Alu | Name=AluJo |
| ADediting_163332 | chr10_110907403_- | SINE | Alu | Name=AluJo |
| ADediting_163333 | chr10_110907415_- | SINE | Alu | Name=AluJo |
| ADediting_163334 | chr10_110907429_- | SINE | Alu | Name=AluJo |
| ADediting_163335 | chr10_110907432_- | SINE | Alu | Name=AluJo |
| ADediting_163336 | chr10_110907433_- | SINE | Alu | Name=AluJo |
| ADediting_163337 | chr10_110907479_- | SINE | Alu | Name=AluJo |
| ADediting_163338 | chr10_110907482_- | SINE | Alu | Name=AluJo |
| ADediting_163339 | chr10_110909332_- | SINE | Alu | Name=AluSc8 |
| ADediting_163340 | chr10_110909359_- | SINE | Alu | Name=AluSc8 |
| ADediting_163341 | chr10_110915204_- | SINE | Alu | Name=AluJb |
| ADediting_163342 | chr10_110915229_- | SINE | Alu | Name=AluJb |
| ADediting_163343 | chr10_110915259_- | SINE | Alu | Name=AluJb |
| ADediting_163344 | chr10_110915273_- | SINE | Alu | Name=AluJb |
| ADediting_163345 | chr10_110915295_- | SINE | Alu | Name=AluJb |
| ADediting_163346 | chr10_110915780_- | SINE | Alu | Name=AluSz6 |
| ADediting_163347 | chr10_110915842_- | SINE | Alu | Name=AluSz6 |
| ADediting_163348 | chr10_110915892_- | SINE | Alu | Name=AluSz6 |
| ADediting_163349 | chr10_110915898_- | SINE | Alu | Name=AluSz6 |
| ADediting_163350 | chr10_110915900_- | SINE | Alu | Name=AluSz6 |
| ADediting_163351 | chr10_110915907_- | SINE | Alu | Name=AluSz6 |
| ADediting_163352 | chr10_110915950_- | SINE | Alu | Name=AluSz6 |
| ADediting_163353 | chr10_110915979_- | SINE | Alu | Name=AluSz6 |
| ADediting_1522396 | chr10_110906141_- | SINE | Alu | Name=AluY |
| ADediting_1522397 | chr10_110906773_- | SINE | Alu | Name=AluSz |
| ADediting_1522398 | chr10_110907376_- | SINE | Alu | Name=AluJo |
| ADediting_1522399 | chr10_110907420_- | SINE | Alu | Name=AluJo |
| ADediting_1522400 | chr10_110909431_- | SINE | Alu | Name=AluSc8 |
| ADediting_1522401 | chr10_110909466_- | SINE | Alu | Name=AluSc8 |
| ADediting_1522402 | chr10_110915809_- | SINE | Alu | Name=AluSz6 |
| ADediting_1522403 | chr10_110915883_- | SINE | Alu | Name=AluSz6 |
| ADediting_1522404 | chr10_110915897_- | SINE | Alu | Name=AluSz6 |
| ADediting_1522405 | chr10_110915899_- | SINE | Alu | Name=AluSz6 |
| ADediting_1522406 | chr10_110915941_- | SINE | Alu | Name=AluSz6 |
| ADediting_1603776 | chr10_110907461_- | SINE | Alu | Name=AluJo |
Top |
RNA A-to-I editing events in the alternative splicing sites for BBIP1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for BBIP1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for BBIP1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
 |
Top |
The effects of the RNA editing to the miRNA binding sites for BBIP1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-3183 | chr10 | 110901118 | 110901124 | 7mer-m8 | 110901117 | 110901139 | 144 | -15.78 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-4723-3p | chr10 | 110901118 | 110901124 | 7mer-m8 | 110901117 | 110901138 | 141 | -17.74 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-6769b-3p | chr10 | 110901118 | 110901124 | 7mer-m8 | 110901117 | 110901137 | 142 | -17.49 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-6826-3p | chr10 | 110901115 | 110901121 | 7mer-m8 | 110901114 | 110901135 | 155 | -19.38 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-6892-3p | chr10 | 110901117 | 110901123 | 7mer-m8 | 110901116 | 110901136 | 140 | -15.51 |
| ADediting_163266 | chr10_110901175_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-545-3p | chr10 | 110901175 | 110901181 | 7mer-m8 | 110901174 | 110901196 | 143 | -12.06 |
| ADediting_163266 | chr10_110901175_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-624-5p | chr10 | 110901169 | 110901176 | 8mer-1a | 110901169 | 110901189 | 153 | -17.4 |
| ADediting_163266 | chr10_110901175_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-634 | chr10 | 110901172 | 110901179 | 8mer-1a | 110901172 | 110901193 | 141 | -12.48 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-188-5p | chr10 | 110901114 | 110901120 | 7mer-m8 | 110901113 | 110901132 | 141 | -10.12 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-320a-5p | chr10 | 110901117 | 110901123 | 7mer-m8 | 110901116 | 110901137 | 147 | -13.46 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-5088-3p | chr10 | 110901115 | 110901122 | 8mer-1a | 110901115 | 110901135 | 141 | -14.65 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-6866-3p | chr10 | 110901114 | 110901120 | 7mer-m8 | 110901113 | 110901133 | 149 | -17.84 |
| ADediting_163265 | chr10_110901119_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-942-5p | chr10 | 110901118 | 110901124 | 7mer-m8 | 110901117 | 110901138 | 142 | -12.53 |
| ADediting_163266 | chr10_110901175_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-1278 | chr10 | 110901169 | 110901175 | 7mer-1a | 110901169 | 110901189 | 147 | -16.35 |
| ADediting_163267 | chr10_110901245_- | ENSG00000214413.8 | ENST00000605265.1 | BBIP1-209 | hsa-miR-4718 | chr10 | 110901241 | 110901247 | 7mer-m8 | 110901240 | 110901259 | 154 | -20.45 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000214413.8 | ENST00000448814.6 | BBIP1-207 | hsa-miR-381-3p | chr10 | 110899946 | 110899953 | 8mer-1a | 110899946 | 110899969 | 151 | -12.63 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000214413.8 | ENST00000651952.1 | BBIP1-212 | hsa-miR-381-3p | chr10 | 110899946 | 110899953 | 8mer-1a | 110899946 | 110899969 | 151 | -12.63 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000214413.8 | ENST00000652043.1 | BBIP1-213 | hsa-miR-381-3p | chr10 | 110899946 | 110899953 | 8mer-1a | 110899946 | 110899969 | 151 | -12.63 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000214413.8 | ENST00000652396.1 | BBIP1-214 | hsa-miR-381-3p | chr10 | 110899946 | 110899953 | 8mer-1a | 110899946 | 110899969 | 151 | -12.63 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000214413.8 | ENST00000652400.1 | BBIP1-215 | hsa-miR-381-3p | chr10 | 110899946 | 110899953 | 8mer-1a | 110899946 | 110899969 | 151 | -12.63 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000214413.8 | ENST00000448814.6 | BBIP1-207 | hsa-miR-5688 | chr10 | 110899935 | 110899941 | 7mer-m8 | 110899934 | 110899956 | 155 | -14.08 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000214413.8 | ENST00000651952.1 | BBIP1-212 | hsa-miR-5688 | chr10 | 110899935 | 110899941 | 7mer-m8 | 110899934 | 110899956 | 155 | -14.08 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000214413.8 | ENST00000652043.1 | BBIP1-213 | hsa-miR-5688 | chr10 | 110899935 | 110899941 | 7mer-m8 | 110899934 | 110899956 | 155 | -14.08 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000214413.8 | ENST00000652396.1 | BBIP1-214 | hsa-miR-5688 | chr10 | 110899935 | 110899941 | 7mer-m8 | 110899934 | 110899956 | 155 | -14.08 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000214413.8 | ENST00000652400.1 | BBIP1-215 | hsa-miR-5688 | chr10 | 110899935 | 110899941 | 7mer-m8 | 110899934 | 110899956 | 155 | -14.08 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for BBIP1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000605265.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_163265 | ENST00000605265.1 | chr10_110901119_- | 3827 | -1154.10 | -1151.20 | -1159.90 |
| ADediting_163266 | ENST00000605265.1 | chr10_110901175_- | 3771 | -1152.30 | -1151.20 | -1159.90 |
| ADediting_163267 | ENST00000605265.1 | chr10_110901245_- | 3701 | -1155.90 | -1151.20 | -1159.90 |
Top |
Relation with ADAR for BBIP1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_163268 | chr10_110905307_- | 5.43189925539193e-08 | 0.42611130540128 | 0.000774538963945784 | 0.271579080809422 | 0.244815440574849 | 0.095543232602301 |
| CER | ADediting_163269 | chr10_110905319_- | 2.27872160999028e-07 | 0.407465325327417 | 0.00188388503818906 | 0.251768764342003 | 0.706906110257461 | 0.0309530337061551 |
| DLPFC | ADediting_163273 | chr10_110905363_- | 0.00232945053001551 | 0.172325656733678 | 0.397835543582775 | 0.0481875484915901 | 3.1749479427943e-10 | 0.347459051416281 |
| DLPFC | ADediting_163276 | chr10_110905373_- | 0.0369387085663876 | 0.118562560104402 | 0.766406020375793 | -0.0169401898858974 | 1.87535954627955e-13 | 0.401757328873693 |
| DLPFC | ADediting_163283 | chr10_110905499_- | 0.0866251717515315 | 0.0974807448682298 | 0.917947078484834 | -0.00587482659426146 | 1.55383006689626e-17 | 0.458693505947101 |
| DLPFC | ADediting_163284 | chr10_110905518_- | 0.0191222676379703 | 0.133026753694622 | 0.489097335237809 | 0.0394325033847754 | 1.08089002136812e-13 | 0.405409408032902 |
| DLPFC | ADediting_163288 | chr10_110906207_- | 0.571301137255347 | 0.0322763902060051 | 0.199541068633874 | -0.0730592980569253 | 1.0082905768498e-12 | 0.39032328356739 |
| CER | ADediting_163288 | chr10_110906207_- | 0.000186629094217957 | 0.300512109146904 | 0.00614489301578619 | 0.2227611195371 | 0.573470905446564 | 0.0463272975005506 |
| DLPFC | ADediting_163289 | chr10_110906211_- | 0.909151534217163 | 0.00650716397815604 | 0.0871065377920933 | -0.0973328077178594 | 1.95906779092493e-12 | 0.38568368183287 |
| DLPFC | ADediting_163290 | chr10_110906212_- | 0.821796558765221 | 0.0128438396839996 | 0.17352104174536 | -0.0774950570537403 | 6.18782800338487e-12 | 0.377472786854002 |
| DLPFC | ADediting_163291 | chr10_110906226_- | 0.79634230730948 | -0.0147168279770937 | 0.0246149419537945 | -0.127636453399977 | 1.89541814195964e-13 | 0.401686372240435 |
| CER | ADediting_163291 | chr10_110906226_- | 8.18773868724323e-06 | 0.355199220760532 | 0.00117440114897501 | 0.26248929273824 | 0.688169763232852 | -0.0330366990976116 |
| DLPFC | ADediting_163292 | chr10_110906227_- | 0.720014915312096 | -0.0204383986143891 | 0.0190567498888953 | -0.133098786032852 | 3.91796609141918e-13 | 0.396803061840057 |
| CER | ADediting_163292 | chr10_110906227_- | 0.000108602723418238 | 0.310765183272541 | 0.00498161432851421 | 0.228166412363448 | 0.333322182112482 | -0.0795315709951668 |
| CER | ADediting_163293 | chr10_110906243_- | 1.15923035539428e-06 | 0.384840022921679 | 0.000720745141328773 | 0.273119665963759 | 0.885060792905231 | 0.0119021640857968 |
| DLPFC | ADediting_163294 | chr10_110906278_- | 0.157935281205822 | 0.0803939495341484 | 0.980577976621701 | 0.00138827099477993 | 9.54912880289824e-10 | 0.338469258467256 |
| TCX | ADediting_163303 | chr10_110906697_- | 0.00366727319858062 | 0.235845909234018 | 0.890120949553601 | 0.0113747860692009 | 1.22413504828424e-05 | 0.348717114556824 |
| TCX | ADediting_163304 | chr10_110906698_- | 0.00634897164951405 | 0.221908607274867 | 0.718207344947018 | 0.0297057400464773 | 3.32102075536209e-05 | 0.331982743210758 |
| TCX | ADediting_163305 | chr10_110906724_- | 0.00263947766038051 | 0.243833490403229 | 0.499551138271834 | 0.0555516593231894 | 8.79913918942623e-06 | 0.354048932944075 |
| CER | ADediting_163307 | chr10_110906728_- | 3.37577591282394e-05 | 0.331700355427256 | 0.0136497339568975 | 0.200998616966757 | 0.610338402832859 | 0.0419404233110513 |
| TCX | ADediting_163307 | chr10_110906728_- | 0.00136981623034816 | 0.259046312092171 | 0.93991372498605 | -0.00620647328382413 | 0.000102622857929082 | 0.311816318795247 |
| TCX | ADediting_163308 | chr10_110906729_- | 0.00491900539099212 | 0.228488333561062 | 0.75363420549785 | 0.025837692146122 | 0.000105082598870906 | 0.311377194743947 |
| CER | ADediting_163311 | chr10_110906753_- | 0.000140358718565193 | 0.305954630406113 | 0.0481210091682681 | 0.161653453470688 | 0.694736949636622 | -0.0323040430734621 |
| CER | ADediting_163314 | chr10_110906797_- | 1.92537993388851e-07 | 0.40971582962617 | 0.0080321458307823 | 0.21568084369275 | 0.477403970958474 | 0.0584501257604613 |
| CER | ADediting_163326 | chr10_110907339_- | 1.09397359118759e-06 | 0.385675451160673 | 0.0083591400322578 | 0.214607614087957 | 0.981948828780705 | -0.00186296519968698 |
| TCX | ADediting_163326 | chr10_110907339_- | 0.0112136788135555 | 0.206551005875323 | 0.898749176696332 | -0.0104765902303399 | 8.16039265373416e-07 | 0.389866842186502 |
| CER | ADediting_163327 | chr10_110907346_- | 5.63523040322774e-05 | 0.322708386729652 | 0.00847412451492899 | 0.214239047366731 | 0.159202045948447 | -0.115524344590862 |
| CER | ADediting_163328 | chr10_110907386_- | 1.50903646132208e-08 | 0.441864857119063 | 0.00115572151012555 | 0.262845334262048 | 0.187881249236329 | 0.108111185312104 |
| TCX | ADediting_163328 | chr10_110907386_- | 0.000739232428262153 | 0.27257863642918 | 0.636216217986607 | 0.0389309694648426 | 1.03069017397808e-09 | 0.472488659472078 |
| STG | ADediting_163328 | chr10_110907386_- | 0.0048505382921658 | 0.30456363085468 | 0.0489536391960399 | 0.215532297123043 | 0.000145315578592488 | 0.402827934726761 |
| TCX | ADediting_163329 | chr10_110907390_- | 0.0616088329291414 | 0.152991564552307 | 0.735367863093376 | -0.0278244980353425 | 1.84649843437542e-08 | 0.439435116730288 |
| CER | ADediting_163331 | chr10_110907398_- | 7.25655077386937e-10 | 0.476278482776737 | 0.000231444611843251 | 0.29632904271184 | 0.395359889220856 | -0.0698968905142573 |
| TCX | ADediting_163331 | chr10_110907398_- | 3.2022259451184e-05 | 0.332610765426145 | 0.0141602965684674 | 0.199946302768472 | 2.50665026861615e-07 | 0.406184632498454 |
| CER | ADediting_163332 | chr10_110907403_- | 7.81850368322733e-08 | 0.421481190498299 | 0.00195622828170711 | 0.250894341873916 | 0.0544693090045009 | -0.157355985859906 |
| TCX | ADediting_163332 | chr10_110907403_- | 0.121483573783627 | 0.126990603404223 | 0.777000977668017 | -0.0233175021693709 | 0.000156458394631304 | 0.303892926167878 |
| CER | ADediting_163334 | chr10_110907429_- | 3.12975301362494e-09 | 0.460178667686487 | 0.000505862098228519 | 0.280569387234675 | 0.158081027537149 | 0.115833647336669 |
| TCX | ADediting_163334 | chr10_110907429_- | 0.00465650566397487 | 0.229879294064692 | 0.990483786820556 | 0.000982057767744121 | 4.24247879673736e-07 | 0.399017663910064 |
| TCX | ADediting_163335 | chr10_110907432_- | 0.00691582399055074 | 0.219662613360976 | 0.927204881307962 | -0.00752250757744476 | 2.21910115060283e-06 | 0.375315651494721 |
| CER | ADediting_163337 | chr10_110907479_- | 2.00995241917113e-11 | 0.512565792603403 | 1.91214587489623e-05 | 0.341357570711423 | 0.369457023960502 | 0.0737971896137275 |
| TCX | ADediting_163337 | chr10_110907479_- | 0.00522363304898351 | 0.226955120133764 | 0.975917366836365 | 0.00248560399241092 | 7.95762927623737e-08 | 0.421255186948801 |
| CER | ADediting_163338 | chr10_110907482_- | 2.1039417837841e-13 | 0.553258135113967 | 4.90088928613172e-07 | 0.39702297427559 | 0.24070118653286 | 0.0963773812872566 |
| TCX | ADediting_163338 | chr10_110907482_- | 0.00763717522402088 | 0.217030068879636 | 0.93863547729183 | 0.00633876272038478 | 1.33925063117429e-07 | 0.414509199064533 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 2.19265371409743e-34 | 0.620543904365309 | 1.34258517974295e-22 | 0.517123477030615 | 9.30312832795923e-10 | 0.338685689857749 |
| AC | 1.10704937578382e-82 | 0.881251053872104 | 4.83484165382067e-51 | 0.773566354551225 | 1.96070566281707e-17 | 0.502951129019612 |
| PCC | 7.22699968869077e-21 | 0.6101956307148 | 1.62911787587403e-17 | 0.565192362001134 | 0.000196159245225369 | 0.266318327567244 |
| CER | 8.63739030530228e-26 | 0.725503319471897 | 8.60098073581759e-09 | 0.448534385562427 | 0.0307013121734199 | 0.176527308822053 |
| TCX | 1.0307446540921e-15 | 0.594653203812729 | 0.128776936920322 | 0.12457964319999 | 1.7597976483259e-17 | 0.622765526251328 |
| FP | 3.30277650753688e-20 | 0.618990614782096 | 4.77897455454882e-27 | 0.695386596103222 | 0.0121065823452329 | 0.18770696540453 |
| IFG | 0.0198520617804884 | 0.462719870667937 | 0.0892720358342 | 0.346963067581796 | 0.098125131945565 | 0.338285554521884 |
| PG | 3.23201941464048e-54 | 0.854449355075572 | 7.14515582057838e-25 | 0.662521761416234 | 0.513290581432644 | 0.0482304922701552 |
| STG | 1.15206351412576e-24 | 0.851132711711486 | 1.46115562853287e-12 | 0.6775682774608 | 0.0138770010693339 | 0.267550530141007 |
Top |
Relation with AD stages for BBIP1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_163328 | chr10_110907386_- | 0.00130414801032152 | 0.308287427302262 |
| TCX | ADediting_163337 | chr10_110907479_- | 0.000690244042320415 | 0.324480561585251 |
| TCX | ADediting_163338 | chr10_110907482_- | 0.00149577059122358 | 0.304676919800941 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 1.71278342225937e-08 | 0.514265467950618 |
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RelatedDrugs for BBIP1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BBIP1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
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