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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for NEK9

check button Gene summary
Gene informationGene symbol

NEK9

Gene ID

91754

Gene nameNIMA related kinase 9
SynonymsAPUG|LCCS10|NC|NERCC|NERCC1
Cytomap

14q24.3

Type of geneprotein-coding
Descriptionserine/threonine-protein kinase Nek9NIMA (never in mitosis gene a)- related kinase 9nercc1 kinasenimA-related protein kinase 9
Modification date20200320
UniProtAcc

Q8TD19,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for NEK9

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_451885(75080087, -), ADediting_451886(75080088, -), ADediting_451887(75080147, -), ADediting_451888(75080150, -), ADediting_451889(75080173, -), ADediting_451890(75080278, -), ADediting_451891(75080283, -), ADediting_451892(75080703, -), ADediting_451893(75080708, -), ADediting_451894(75080709, -), ADediting_451895(75080773, -), ADediting_451896(75080779, -), ADediting_451897(75080841, -), ADediting_451898(75080861, -), ADediting_451899(75080904, -), ADediting_451900(75080905, -), ADediting_451901(75081082, -), ADediting_451902(75081092, -), ADediting_451903(75081125, -), ADediting_451904(75081128, -), ADediting_451905(75081145, -), ADediting_451906(75081216, -), ADediting_451907(75085089, -), ADediting_451908(75085109, -), ADediting_451909(75085224, -), ADediting_451910(75086106, -), ADediting_451911(75086734, -), ADediting_451912(75086740, -), ADediting_451913(75086743, -), ADediting_451914(75086784, -), ADediting_451915(75086819, -), ADediting_451916(75086820, -), ADediting_451917(75086823, -), ADediting_451918(75086843, -), ADediting_451919(75092047, -), ADediting_451920(75092048, -), ADediting_451921(75092065, -), ADediting_451922(75092076, -), ADediting_451923(75092091, -), ADediting_451924(75092117, -), ADediting_451925(75092118, -), ADediting_451926(75092136, -), ADediting_451927(75092179, -), ADediting_451928(75092218, -), ADediting_451929(75092334, -), ADediting_451930(75092335, -), ADediting_451931(75092359, -), ADediting_451932(75092363, -), ADediting_451933(75092391, -), ADediting_451934(75092404, -), ADediting_451935(75092405, -), ADediting_451936(75092423, -), ADediting_451937(75092435, -), ADediting_451938(75093121, -), ADediting_451939(75093526, -), ADediting_451940(75093530, -), ADediting_451941(75093539, -), ADediting_451942(75093550, -), ADediting_451943(75093582, -), ADediting_451944(75093586, -), ADediting_451945(75093592, -), ADediting_451946(75093598, -), ADediting_451947(75093610, -), ADediting_451948(75093631, -), ADediting_451949(75093701, -), ADediting_451950(75093706, -), ADediting_451951(75094341, -), ADediting_451952(75094369, -), ADediting_451953(75094402, -), ADediting_451954(75094406, -), ADediting_451955(75094411, -), ADediting_451956(75094415, -), ADediting_451957(75094444, -), ADediting_451958(75094523, -), ADediting_451959(75094533, -), ADediting_451960(75094537, -), ADediting_451961(75094551, -), ADediting_451962(75094552, -), ADediting_451963(75094561, -), ADediting_451964(75094566, -), ADediting_451965(75094593, -), ADediting_451966(75094617, -), ADediting_451967(75094640, -), ADediting_451968(75094652, -), ADediting_451969(75094658, -), ADediting_451970(75094668, -), ADediting_451971(75094671, -), ADediting_451972(75094672, -), ADediting_451973(75094680, -), ADediting_451974(75094697, -), ADediting_451975(75094698, -), ADediting_451976(75094704, -), ADediting_451977(75094718, -), ADediting_451978(75094723, -), ADediting_451979(75094733, -), ADediting_451980(75094734, -), ADediting_451981(75094741, -), ADediting_451982(75094754, -), ADediting_451983(75094758, -), ADediting_451984(75094792, -), ADediting_451985(75104348, -), ADediting_451986(75106099, -), ADediting_451987(75106173, -), ADediting_451988(75106192, -), ADediting_451989(75106201, -), ADediting_451990(75106290, -), ADediting_451991(75106320, -), ADediting_451992(75115320, -), ADediting_451993(75115389, -), ADediting_451994(75116201, -), ADediting_451995(75116243, -), ADediting_451996(75116385, -), ADediting_451997(75121807, -), ADediting_451998(75121813, -), ADediting_451999(75121862, -), ADediting_452000(75122245, -), ADediting_452001(75122601, -), ADediting_452002(75122602, -), ADediting_452003(75122610, -), ADediting_452004(75122616, -), ADediting_452005(75122633, -), ADediting_452006(75122637, -), ADediting_452007(75122642, -), ADediting_452008(75122643, -), ADediting_452009(75122661, -), ADediting_452010(75122669, -), ADediting_452011(75122672, -), ADediting_452012(75122673, -), ADediting_452013(75122675, -), ADediting_452014(75122707, -), ADediting_452015(75122709, -), ADediting_452016(75122738, -), ADediting_452017(75122884, -), ADediting_452018(75122896, -), ADediting_452019(75122937, -), ADediting_452020(75122988, -), ADediting_452021(75122994, -), ADediting_452022(75122996, -), ADediting_452023(75122998, -), ADediting_452024(75123003, -), ADediting_452025(75123022, -), ADediting_452026(75123037, -), ADediting_452027(75123209, -), ADediting_452028(75123218, -), ADediting_452029(75123235, -), ADediting_452030(75123238, -), ADediting_452031(75123252, -), ADediting_452032(75123253, -), ADediting_452033(75123293, -), ADediting_452034(75123315, -), ADediting_452035(75123318, -), ADediting_452036(75123319, -), ADediting_452037(75123341, -), ADediting_452038(75123362, -), ADediting_452039(75124891, -), ADediting_452040(75124902, -), ADediting_452041(75124909, -), ADediting_452042(75125025, -), ADediting_452043(75125040, -), ADediting_452044(75125047, -), ADediting_452045(75125069, -), ADediting_1537892(75086782, -), ADediting_1537893(75092108, -), ADediting_1537894(75092244, -), ADediting_1537895(75092302, -), ADediting_1537896(75092319, -), ADediting_1537897(75093522, -), ADediting_1537898(75093565, -), ADediting_1537899(75093569, -), ADediting_1537900(75093689, -), ADediting_1537901(75093705, -), ADediting_1537902(75094337, -), ADediting_1537903(75094530, -), ADediting_1537904(75094553, -), ADediting_1537905(75094578, -), ADediting_1537906(75094636, -), ADediting_1537907(75094645, -), ADediting_1537908(75094778, -), ADediting_1537909(75096027, -), ADediting_1537910(75116228, -), ADediting_1537911(75116253, -), ADediting_1537912(75116258, -), ADediting_1537913(75116313, -), ADediting_1537914(75116315, -), ADediting_1620487(75096660, -), ADediting_1620488(75116241, -), ADediting_1620489(75116380, -),

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RNA editing positional annotations for NEK9 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_451885chr14_75080087_-UTR3
ADediting_451886chr14_75080088_-UTR3
ADediting_451887chr14_75080147_-UTR3
ADediting_451888chr14_75080150_-UTR3
ADediting_451889chr14_75080173_-UTR3
ADediting_451890chr14_75080278_-UTR3
ADediting_451891chr14_75080283_-UTR3
ADediting_451892chr14_75080703_-UTR3
ADediting_451893chr14_75080708_-UTR3
ADediting_451894chr14_75080709_-UTR3
ADediting_451895chr14_75080773_-UTR3
ADediting_451896chr14_75080779_-UTR3
ADediting_451897chr14_75080841_-UTR3
ADediting_451898chr14_75080861_-UTR3
ADediting_451899chr14_75080904_-UTR3
ADediting_451900chr14_75080905_-UTR3
ADediting_451901chr14_75081082_-UTR3
ADediting_451902chr14_75081092_-UTR3
ADediting_451903chr14_75081125_-UTR3
ADediting_451904chr14_75081128_-UTR3
ADediting_451905chr14_75081145_-UTR3
ADediting_451906chr14_75081216_-UTR3
ADediting_451907chr14_75085089_-intronic
ADediting_451908chr14_75085109_-intronic
ADediting_451909chr14_75085224_-intronic
ADediting_451910chr14_75086106_-intronic
ADediting_451911chr14_75086734_-intronic
ADediting_451912chr14_75086740_-intronic
ADediting_451913chr14_75086743_-intronic
ADediting_451914chr14_75086784_-intronic
ADediting_451915chr14_75086819_-intronic
ADediting_451916chr14_75086820_-intronic
ADediting_451917chr14_75086823_-intronic
ADediting_451918chr14_75086843_-intronic
ADediting_451919chr14_75092047_-intronic
ADediting_451920chr14_75092048_-intronic
ADediting_451921chr14_75092065_-intronic
ADediting_451922chr14_75092076_-intronic
ADediting_451923chr14_75092091_-intronic
ADediting_451924chr14_75092117_-intronic
ADediting_451925chr14_75092118_-intronic
ADediting_451926chr14_75092136_-intronic
ADediting_451927chr14_75092179_-intronic
ADediting_451928chr14_75092218_-intronic
ADediting_451929chr14_75092334_-intronic
ADediting_451930chr14_75092335_-intronic
ADediting_451931chr14_75092359_-intronic
ADediting_451932chr14_75092363_-intronic
ADediting_451933chr14_75092391_-intronic
ADediting_451934chr14_75092404_-intronic
ADediting_451935chr14_75092405_-intronic
ADediting_451936chr14_75092423_-intronic
ADediting_451937chr14_75092435_-intronic
ADediting_451938chr14_75093121_-intronic
ADediting_451939chr14_75093526_-intronic
ADediting_451940chr14_75093530_-intronic
ADediting_451941chr14_75093539_-intronic
ADediting_451942chr14_75093550_-intronic
ADediting_451943chr14_75093582_-intronic
ADediting_451944chr14_75093586_-intronic
ADediting_451945chr14_75093592_-intronic
ADediting_451946chr14_75093598_-intronic
ADediting_451947chr14_75093610_-intronic
ADediting_451948chr14_75093631_-intronic
ADediting_451949chr14_75093701_-intronic
ADediting_451950chr14_75093706_-intronic
ADediting_451951chr14_75094341_-intronic
ADediting_451952chr14_75094369_-intronic
ADediting_451953chr14_75094402_-intronic
ADediting_451954chr14_75094406_-intronic
ADediting_451955chr14_75094411_-intronic
ADediting_451956chr14_75094415_-intronic
ADediting_451957chr14_75094444_-intronic
ADediting_451958chr14_75094523_-intronic
ADediting_451959chr14_75094533_-intronic
ADediting_451960chr14_75094537_-intronic
ADediting_451961chr14_75094551_-intronic
ADediting_451962chr14_75094552_-intronic
ADediting_451963chr14_75094561_-intronic
ADediting_451964chr14_75094566_-intronic
ADediting_451965chr14_75094593_-intronic
ADediting_451966chr14_75094617_-intronic
ADediting_451967chr14_75094640_-intronic
ADediting_451968chr14_75094652_-intronic
ADediting_451969chr14_75094658_-intronic
ADediting_451970chr14_75094668_-intronic
ADediting_451971chr14_75094671_-intronic
ADediting_451972chr14_75094672_-intronic
ADediting_451973chr14_75094680_-intronic
ADediting_451974chr14_75094697_-intronic
ADediting_451975chr14_75094698_-intronic
ADediting_451976chr14_75094704_-intronic
ADediting_451977chr14_75094718_-intronic
ADediting_451978chr14_75094723_-intronic
ADediting_451979chr14_75094733_-intronic
ADediting_451980chr14_75094734_-intronic
ADediting_451981chr14_75094741_-intronic
ADediting_451982chr14_75094754_-intronic
ADediting_451983chr14_75094758_-intronic
ADediting_451984chr14_75094792_-intronic
ADediting_451985chr14_75104348_-intronic
ADediting_451986chr14_75106099_-intronic
ADediting_451987chr14_75106173_-intronic
ADediting_451988chr14_75106192_-intronic
ADediting_451989chr14_75106201_-intronic
ADediting_451990chr14_75106290_-intronic
ADediting_451991chr14_75106320_-intronic
ADediting_451992chr14_75115320_-intronic
ADediting_451993chr14_75115389_-intronic
ADediting_451994chr14_75116201_-intronic
ADediting_451995chr14_75116243_-intronic
ADediting_451996chr14_75116385_-intronic
ADediting_451997chr14_75121807_-intronic
ADediting_451998chr14_75121813_-intronic
ADediting_451999chr14_75121862_-intronic
ADediting_452000chr14_75122245_-intronic
ADediting_452001chr14_75122601_-intronic
ADediting_452002chr14_75122602_-intronic
ADediting_452003chr14_75122610_-intronic
ADediting_452004chr14_75122616_-intronic
ADediting_452005chr14_75122633_-intronic
ADediting_452006chr14_75122637_-intronic
ADediting_452007chr14_75122642_-intronic
ADediting_452008chr14_75122643_-intronic
ADediting_452009chr14_75122661_-intronic
ADediting_452010chr14_75122669_-intronic
ADediting_452011chr14_75122672_-intronic
ADediting_452012chr14_75122673_-intronic
ADediting_452013chr14_75122675_-intronic
ADediting_452014chr14_75122707_-intronic
ADediting_452015chr14_75122709_-intronic
ADediting_452016chr14_75122738_-intronic
ADediting_452017chr14_75122884_-intronic
ADediting_452018chr14_75122896_-intronic
ADediting_452019chr14_75122937_-intronic
ADediting_452020chr14_75122988_-intronic
ADediting_452021chr14_75122994_-intronic
ADediting_452022chr14_75122996_-intronic
ADediting_452023chr14_75122998_-intronic
ADediting_452024chr14_75123003_-intronic
ADediting_452025chr14_75123022_-intronic
ADediting_452026chr14_75123037_-intronic
ADediting_452027chr14_75123209_-intronic
ADediting_452028chr14_75123218_-intronic
ADediting_452029chr14_75123235_-intronic
ADediting_452030chr14_75123238_-intronic
ADediting_452031chr14_75123252_-intronic
ADediting_452032chr14_75123253_-intronic
ADediting_452033chr14_75123293_-intronic
ADediting_452034chr14_75123315_-intronic
ADediting_452035chr14_75123318_-intronic
ADediting_452036chr14_75123319_-intronic
ADediting_452037chr14_75123341_-intronic
ADediting_452038chr14_75123362_-intronic
ADediting_452039chr14_75124891_-intronic
ADediting_452040chr14_75124902_-intronic
ADediting_452041chr14_75124909_-intronic
ADediting_452042chr14_75125025_-intronic
ADediting_452043chr14_75125040_-intronic
ADediting_452044chr14_75125047_-intronic
ADediting_452045chr14_75125069_-intronic
ADediting_1537892chr14_75086782_-intronic
ADediting_1537893chr14_75092108_-intronic
ADediting_1537894chr14_75092244_-intronic
ADediting_1537895chr14_75092302_-intronic
ADediting_1537896chr14_75092319_-intronic
ADediting_1537897chr14_75093522_-intronic
ADediting_1537898chr14_75093565_-intronic
ADediting_1537899chr14_75093569_-intronic
ADediting_1537900chr14_75093689_-intronic
ADediting_1537901chr14_75093705_-intronic
ADediting_1537902chr14_75094337_-intronic
ADediting_1537903chr14_75094530_-intronic
ADediting_1537904chr14_75094553_-intronic
ADediting_1537905chr14_75094578_-intronic
ADediting_1537906chr14_75094636_-intronic
ADediting_1537907chr14_75094645_-intronic
ADediting_1537908chr14_75094778_-intronic
ADediting_1537909chr14_75096027_-intronic
ADediting_1537910chr14_75116228_-intronic
ADediting_1537911chr14_75116253_-intronic
ADediting_1537912chr14_75116258_-intronic
ADediting_1537913chr14_75116313_-intronic
ADediting_1537914chr14_75116315_-intronic
ADediting_1620487chr14_75096660_-intronic
ADediting_1620488chr14_75116241_-intronic
ADediting_1620489chr14_75116380_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_451885chr14_75080087_-SINEAluName=AluSc
ADediting_451886chr14_75080088_-SINEAluName=AluSc
ADediting_451887chr14_75080147_-SINEAluName=AluSc
ADediting_451888chr14_75080150_-SINEAluName=AluSc
ADediting_451889chr14_75080173_-SINEAluName=AluSc
ADediting_451890chr14_75080278_-SINEAluName=AluSc
ADediting_451891chr14_75080283_-SINEAluName=AluSc
ADediting_451892chr14_75080703_-SINEAluName=AluY
ADediting_451893chr14_75080708_-SINEAluName=AluY
ADediting_451894chr14_75080709_-SINEAluName=AluY
ADediting_451895chr14_75080773_-SINEAluName=AluY
ADediting_451896chr14_75080779_-SINEAluName=AluY
ADediting_451897chr14_75080841_-SINEAluName=AluY
ADediting_451898chr14_75080861_-SINEAluName=AluY
ADediting_451899chr14_75080904_-SINEAluName=AluY
ADediting_451900chr14_75080905_-SINEAluName=AluY
ADediting_451901chr14_75081082_-SINEAluName=AluY
ADediting_451902chr14_75081092_-SINEAluName=AluY
ADediting_451903chr14_75081125_-SINEAluName=AluY
ADediting_451904chr14_75081128_-SINEAluName=AluY
ADediting_451905chr14_75081145_-SINEAluName=AluY
ADediting_451906chr14_75081216_-SINEAluName=AluY
ADediting_451907chr14_75085089_-SINEAluName=AluJb
ADediting_451908chr14_75085109_-SINEAluName=AluJb
ADediting_451909chr14_75085224_-SINEAluName=AluJb
ADediting_451910chr14_75086106_-SINEAluName=AluSx4
ADediting_451911chr14_75086734_-SINEAluName=AluSc
ADediting_451912chr14_75086740_-SINEAluName=AluSc
ADediting_451913chr14_75086743_-SINEAluName=AluSc
ADediting_451914chr14_75086784_-SINEAluName=AluSc
ADediting_451915chr14_75086819_-SINEAluName=AluSc
ADediting_451916chr14_75086820_-SINEAluName=AluSc
ADediting_451917chr14_75086823_-SINEAluName=AluSc
ADediting_451918chr14_75086843_-SINEAluName=AluSc
ADediting_451919chr14_75092047_-SINEAluName=AluSx
ADediting_451920chr14_75092048_-SINEAluName=AluSx
ADediting_451921chr14_75092065_-SINEAluName=AluSx
ADediting_451922chr14_75092076_-SINEAluName=AluSx
ADediting_451923chr14_75092091_-SINEAluName=AluSx
ADediting_451924chr14_75092117_-SINEAluName=AluSx
ADediting_451925chr14_75092118_-SINEAluName=AluSx
ADediting_451926chr14_75092136_-SINEAluName=AluSx
ADediting_451927chr14_75092179_-SINEAluName=AluSx
ADediting_451928chr14_75092218_-SINEAluName=AluSx
ADediting_451929chr14_75092334_-SINEAluName=AluSx1
ADediting_451930chr14_75092335_-SINEAluName=AluSx1
ADediting_451931chr14_75092359_-SINEAluName=AluSx1
ADediting_451932chr14_75092363_-SINEAluName=AluSx1
ADediting_451933chr14_75092391_-SINEAluName=AluSx1
ADediting_451934chr14_75092404_-SINEAluName=AluSx1
ADediting_451935chr14_75092405_-SINEAluName=AluSx1
ADediting_451936chr14_75092423_-SINEAluName=AluSx1
ADediting_451937chr14_75092435_-SINEAluName=AluSx1
ADediting_451938chr14_75093121_-DNAhAT-CharlieName=MER3
ADediting_451939chr14_75093526_-SINEAluName=AluSc
ADediting_451940chr14_75093530_-SINEAluName=AluSc
ADediting_451941chr14_75093539_-SINEAluName=AluSc
ADediting_451942chr14_75093550_-SINEAluName=AluSc
ADediting_451943chr14_75093582_-SINEAluName=AluSc
ADediting_451944chr14_75093586_-SINEAluName=AluSc
ADediting_451945chr14_75093592_-SINEAluName=AluSc
ADediting_451946chr14_75093598_-SINEAluName=AluSc
ADediting_451947chr14_75093610_-SINEAluName=AluSc
ADediting_451948chr14_75093631_-SINEAluName=AluSc
ADediting_451949chr14_75093701_-SINEAluName=AluSc
ADediting_451950chr14_75093706_-SINEAluName=AluSc
ADediting_451951chr14_75094341_-SINEAluName=AluJr4
ADediting_451952chr14_75094369_-SINEAluName=AluJr4
ADediting_451953chr14_75094402_-SINEAluName=AluJr4
ADediting_451954chr14_75094406_-SINEAluName=AluJr4
ADediting_451955chr14_75094411_-SINEAluName=AluJr4
ADediting_451956chr14_75094415_-SINEAluName=AluJr4
ADediting_451957chr14_75094444_-SINEAluName=AluJr4
ADediting_451958chr14_75094523_-SINEAluName=AluSz6
ADediting_451959chr14_75094533_-SINEAluName=AluSz6
ADediting_451960chr14_75094537_-SINEAluName=AluSz6
ADediting_451961chr14_75094551_-SINEAluName=AluSz6
ADediting_451962chr14_75094552_-SINEAluName=AluSz6
ADediting_451963chr14_75094561_-SINEAluName=AluSz6
ADediting_451964chr14_75094566_-SINEAluName=AluSz6
ADediting_451965chr14_75094593_-SINEAluName=AluSz6
ADediting_451966chr14_75094617_-SINEAluName=AluSz6
ADediting_451967chr14_75094640_-SINEAluName=AluSz6
ADediting_451968chr14_75094652_-SINEAluName=AluSz6
ADediting_451969chr14_75094658_-SINEAluName=AluSz6
ADediting_451970chr14_75094668_-SINEAluName=AluSz6
ADediting_451971chr14_75094671_-SINEAluName=AluSz6
ADediting_451972chr14_75094672_-SINEAluName=AluSz6
ADediting_451973chr14_75094680_-SINEAluName=AluSz6
ADediting_451974chr14_75094697_-SINEAluName=AluSz6
ADediting_451975chr14_75094698_-SINEAluName=AluSz6
ADediting_451976chr14_75094704_-SINEAluName=AluSz6
ADediting_451977chr14_75094718_-SINEAluName=AluSz6
ADediting_451978chr14_75094723_-SINEAluName=AluSz6
ADediting_451979chr14_75094733_-SINEAluName=AluSz6
ADediting_451980chr14_75094734_-SINEAluName=AluSz6
ADediting_451981chr14_75094741_-SINEAluName=AluSz6
ADediting_451982chr14_75094754_-SINEAluName=AluSz6
ADediting_451983chr14_75094758_-SINEAluName=AluSz6
ADediting_451984chr14_75094792_-SINEAluName=AluSz6
ADediting_451985chr14_75104348_-SINEAluName=AluSq
ADediting_451986chr14_75106099_-SINEAluName=AluSx3
ADediting_451987chr14_75106173_-SINEAluName=AluSx3
ADediting_451988chr14_75106192_-SINEAluName=AluSx3
ADediting_451989chr14_75106201_-SINEAluName=AluSx3
ADediting_451990chr14_75106290_-SINEAluName=AluSx3
ADediting_451991chr14_75106320_-SINEAluName=AluSx3
ADediting_451992chr14_75115320_-SINEAluName=AluSx
ADediting_451993chr14_75115389_-SINEAluName=AluSx
ADediting_451994chr14_75116201_-SINEAluName=AluJr
ADediting_451995chr14_75116243_-SINEAluName=AluJr
ADediting_451996chr14_75116385_-SINEAluName=AluJr
ADediting_451997chr14_75121807_-SINEAluName=AluSz6
ADediting_451998chr14_75121813_-SINEAluName=AluSz6
ADediting_451999chr14_75121862_-SINEAluName=AluSz6
ADediting_452001chr14_75122601_-SINEAluName=AluSc5
ADediting_452002chr14_75122602_-SINEAluName=AluSc5
ADediting_452003chr14_75122610_-SINEAluName=AluSc5
ADediting_452004chr14_75122616_-SINEAluName=AluSc5
ADediting_452005chr14_75122633_-SINEAluName=AluSc5
ADediting_452006chr14_75122637_-SINEAluName=AluSc5
ADediting_452007chr14_75122642_-SINEAluName=AluSc5
ADediting_452008chr14_75122643_-SINEAluName=AluSc5
ADediting_452009chr14_75122661_-SINEAluName=AluSc5
ADediting_452010chr14_75122669_-SINEAluName=AluSc5
ADediting_452011chr14_75122672_-SINEAluName=AluSc5
ADediting_452012chr14_75122673_-SINEAluName=AluSc5
ADediting_452013chr14_75122675_-SINEAluName=AluSc5
ADediting_452014chr14_75122707_-SINEAluName=AluSc5
ADediting_452015chr14_75122709_-SINEAluName=AluSc5
ADediting_452016chr14_75122738_-SINEAluName=AluSc5
ADediting_452017chr14_75122884_-SINEAluName=AluJb
ADediting_452018chr14_75122896_-SINEAluName=AluJb
ADediting_452019chr14_75122937_-SINEAluName=AluJb
ADediting_452020chr14_75122988_-SINEAluName=AluJb
ADediting_452021chr14_75122994_-SINEAluName=AluJb
ADediting_452022chr14_75122996_-SINEAluName=AluJb
ADediting_452023chr14_75122998_-SINEAluName=AluJb
ADediting_452024chr14_75123003_-SINEAluName=AluJb
ADediting_452025chr14_75123022_-SINEAluName=AluJb
ADediting_452026chr14_75123037_-SINEAluName=AluJb
ADediting_452027chr14_75123209_-SINEAluName=AluSp
ADediting_452028chr14_75123218_-SINEAluName=AluSp
ADediting_452029chr14_75123235_-SINEAluName=AluSp
ADediting_452030chr14_75123238_-SINEAluName=AluSp
ADediting_452031chr14_75123252_-SINEAluName=AluSp
ADediting_452032chr14_75123253_-SINEAluName=AluSp
ADediting_452033chr14_75123293_-SINEAluName=AluSp
ADediting_452034chr14_75123315_-SINEAluName=AluSp
ADediting_452035chr14_75123318_-SINEAluName=AluSp
ADediting_452036chr14_75123319_-SINEAluName=AluSp
ADediting_452037chr14_75123341_-SINEAluName=AluSp
ADediting_452038chr14_75123362_-SINEAluName=AluSp
ADediting_452039chr14_75124891_-SINEAluName=AluJr
ADediting_452040chr14_75124902_-SINEAluName=AluJr
ADediting_452041chr14_75124909_-SINEAluName=AluJr
ADediting_452042chr14_75125025_-SINEAluName=AluJr
ADediting_452043chr14_75125040_-SINEAluName=AluJr
ADediting_452044chr14_75125047_-SINEAluName=AluJr
ADediting_452045chr14_75125069_-SINEAluName=AluJr
ADediting_1537892chr14_75086782_-SINEAluName=AluSc
ADediting_1537893chr14_75092108_-SINEAluName=AluSx
ADediting_1537894chr14_75092244_-SINEAluName=AluSx
ADediting_1537895chr14_75092302_-SINEAluName=AluSx1
ADediting_1537896chr14_75092319_-SINEAluName=AluSx1
ADediting_1537897chr14_75093522_-SINEAluName=AluSc
ADediting_1537898chr14_75093565_-SINEAluName=AluSc
ADediting_1537899chr14_75093569_-SINEAluName=AluSc
ADediting_1537900chr14_75093689_-SINEAluName=AluSc
ADediting_1537901chr14_75093705_-SINEAluName=AluSc
ADediting_1537902chr14_75094337_-SINEAluName=AluJr4
ADediting_1537903chr14_75094530_-SINEAluName=AluSz6
ADediting_1537904chr14_75094553_-SINEAluName=AluSz6
ADediting_1537905chr14_75094578_-SINEAluName=AluSz6
ADediting_1537906chr14_75094636_-SINEAluName=AluSz6
ADediting_1537907chr14_75094645_-SINEAluName=AluSz6
ADediting_1537908chr14_75094778_-SINEAluName=AluSz6
ADediting_1537909chr14_75096027_-SINEAluName=AluSx4
ADediting_1537910chr14_75116228_-SINEAluName=AluJr
ADediting_1537911chr14_75116253_-SINEAluName=AluJr
ADediting_1537912chr14_75116258_-SINEAluName=AluJr
ADediting_1537913chr14_75116313_-SINEAluName=AluJr
ADediting_1537914chr14_75116315_-SINEAluName=AluJr
ADediting_1620487chr14_75096660_-SINEAluName=AluSq2
ADediting_1620488chr14_75116241_-SINEAluName=AluJr
ADediting_1620489chr14_75116380_-SINEAluName=AluJr

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RNA A-to-I editing events in the alternative splicing sites for NEK9

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_1537892chr14_75086782_-75086775:750867835ss2eCAGGTGTGC6.46CGGGTGTGC4.15
ESADediting_1537892chr14_75086782_-75086775:750867835ss2eCAGGTGTGC6.46CGGGTGTGC4.15

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NEK9

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for NEK9

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for NEK9

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_451885chr14_75080087_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-3189-3pchr1475080086750800927mer-m87508008575080104149-22.73
ADediting_451885chr14_75080087_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6813-3pchr1475080085750800917mer-m87508008475080104140-11.6
ADediting_451886chr14_75080088_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-326chr1475080086750800927mer-m87508008575080104140-13.37
ADediting_451886chr14_75080088_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-330-5pchr1475080086750800927mer-m87508008575080106140-20.32
ADediting_451886chr14_75080088_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4314chr1475080087750800937mer-m87508008675080103140-21.18
ADediting_451886chr14_75080088_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-514a-5pchr1475080085750800917mer-m87508008475080107146-18.76
ADediting_451887chr14_75080147_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-433-5pchr1475080146750801527mer-m87508014575080168163-28.05
ADediting_451890chr14_75080278_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4537chr1475080273750802808mer-1a7508027375080295151-25.93
ADediting_451894chr14_75080709_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6075chr1475080708750807158mer-1a7508070875080730144-23.87
ADediting_451896chr14_75080779_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-140-3pchr1475080777750807837mer-m87508077675080796155-25.24
ADediting_451899chr14_75080904_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-8052chr1475080899750809057mer-1a7508089975080917140-24.15
ADediting_451900chr14_75080905_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-513a-5pchr1475080904750809107mer-m87508090375080920144-16.68
ADediting_451900chr14_75080905_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-638chr1475080899750809057mer-1a7508089975080923159-35.56
ADediting_451901chr14_75081082_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-140-3pchr1475081080750810867mer-m87508107975081099147-22.13
ADediting_451902chr14_75081092_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4258chr1475081090750810967mer-m87508108975081107149-23.88
ADediting_451903chr14_75081125_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-222-5pchr1475081123750811308mer-1a7508112375081144144-9.86
ADediting_451903chr14_75081125_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-30a-3pchr1475081121750811288mer-1a7508112175081145150-11.66
ADediting_451903chr14_75081125_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-30d-3pchr1475081121750811288mer-1a7508112175081147150-16.61
ADediting_451903chr14_75081125_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-30e-3pchr1475081121750811288mer-1a7508112175081145150-14.38
ADediting_451903chr14_75081125_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-936chr1475081124750811318mer-1a7508112475081146159-23.54
ADediting_451904chr14_75081128_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-374b-3pchr1475081123750811308mer-1a7508112375081145149-13.05
ADediting_451906chr14_75081216_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-8052chr1475081211750812177mer-1a7508121175081229140-24.15

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_451886chr14_75080088_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-887-5pchr1475080087750800948mer-1a7508008775080107147-13.82
ADediting_451890chr14_75080278_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-3160-3pchr1475080273750802808mer-1a7508027375080294150-20.6
ADediting_451892chr14_75080703_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4765chr1475080700750807067mer-m87508069975080719142-13.78
ADediting_451892chr14_75080703_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-8079chr1475080701750807077mer-m87508070075080720153-17.62
ADediting_451896chr14_75080779_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-7151-3pchr1475080779750807857mer-m87508077875080798140-17.98
ADediting_451897chr14_75080841_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-892achr1475080839750808457mer-m87508083875080858140-15.2
ADediting_451899chr14_75080904_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-10399-5pchr1475080903750809097mer-m87508090275080923144-11.2
ADediting_451899chr14_75080904_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-5089-5pchr1475080899750809057mer-m87508089875080920148-14.13
ADediting_451899chr14_75080904_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6504-3pchr1475080903750809097mer-m87508090275080923148-14.35
ADediting_451900chr14_75080905_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-10399-5pchr1475080903750809097mer-m87508090275080923144-11.2
ADediting_451900chr14_75080905_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6504-3pchr1475080903750809097mer-m87508090275080923148-14.35
ADediting_451900chr14_75080905_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-7151-3pchr1475080904750809118mer-1a7508090475080924144-16.51
ADediting_451901chr14_75081082_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-7151-3pchr1475081082750810887mer-m87508108175081101140-16.43
ADediting_451901chr14_75081082_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-8052chr1475081076750810827mer-1a7508107675081096141-21.77
ADediting_451902chr14_75081092_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-3064-3pchr1475081092750810987mer-m87508109175081112151-19.9
ADediting_451902chr14_75081092_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6727-3pchr1475081090750810967mer-m87508108975081108153-25.08
ADediting_451904chr14_75081128_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6832-5pchr1475081127750811337mer-m87508112675081148146-16.09
ADediting_451905chr14_75081145_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-892achr1475081143750811497mer-m87508114275081162140-15.2
ADediting_451906chr14_75081216_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-10399-5pchr1475081215750812217mer-m87508121475081235144-10.39
ADediting_451906chr14_75081216_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-5089-5pchr1475081211750812177mer-m87508121075081232148-14.13
ADediting_451906chr14_75081216_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-6504-3pchr1475081215750812217mer-m87508121475081235152-15.11

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1471004chr9_63819627_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4477bchr1475081545750815528mer-1a7508154575081567163-17.29
ADediting_1535954chr14_101045974_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-381-3pchr1475082757750827637mer-m87508275675082777158-17.94
ADediting_843620chr2_207754818_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4775chr1475080805750808117mer-m87508080475080825162-12.64
ADediting_843620chr2_207754818_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4775chr1475081454750814607mer-m87508145375081474160-10.79
ADediting_843620chr2_207754818_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4775chr1475083735750837417mer-m87508373475083755160-12.18

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_107020chr1_37500952_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-5581-3pchr1475082088750820947mer-m87508208775082113141-13.72
ADediting_1471003chr9_63819626_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4477bchr1475079424750794307mer-m87507942375079444149-9.53
ADediting_1471003chr9_63819626_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4477bchr1475083272750832787mer-m87508327175083292148-7.95
ADediting_1471004chr9_63819627_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4477bchr1475079424750794307mer-m87507942375079444149-9.53
ADediting_1471004chr9_63819627_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4477bchr1475083272750832787mer-m87508327175083292148-7.95
ADediting_1643790chr3_121049689_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-5682chr1475079768750797747mer-m87507976775079788140-21.41
ADediting_291761chr11_93733708_-ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-1304-3pchr1475083906750839127mer-m87508390575083926147-15.41
ADediting_843620chr2_207754818_+ENSG00000119638.13ENST00000238616.10NEK9-201hsa-miR-4775chr1475081108750811147mer-m87508110775081129153-7.86

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NEK9

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000238616.10protein_codingSoverviewSoverview
ENST00000555763.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_451885ENST00000238616.10chr14_75080087_-7544-3071.10-3071.40-3089.50
ADediting_451886ENST00000238616.10chr14_75080088_-7543-3071.50-3071.40-3089.50
ADediting_451887ENST00000238616.10chr14_75080147_-7484-3074.80-3071.40-3089.50
ADediting_451888ENST00000238616.10chr14_75080150_-7481-3071.00-3071.40-3089.50
ADediting_451889ENST00000238616.10chr14_75080173_-7458-3071.40-3071.40-3089.50
ADediting_451890ENST00000238616.10chr14_75080278_-7353-3070.70-3071.40-3089.50
ADediting_451891ENST00000238616.10chr14_75080283_-7348-3070.90-3071.40-3089.50
ADediting_451892ENST00000238616.10chr14_75080703_-6928-3074.20-3071.40-3089.50
ADediting_451893ENST00000238616.10chr14_75080708_-6923-3071.40-3071.40-3089.50
ADediting_451894ENST00000238616.10chr14_75080709_-6922-3071.40-3071.40-3089.50
ADediting_451895ENST00000238616.10chr14_75080773_-6858-3070.70-3071.40-3089.50
ADediting_451896ENST00000238616.10chr14_75080779_-6852-3071.40-3071.40-3089.50
ADediting_451897ENST00000238616.10chr14_75080841_-6790-3071.40-3071.40-3089.50
ADediting_451898ENST00000238616.10chr14_75080861_-6770-3071.40-3071.40-3089.50
ADediting_451899ENST00000238616.10chr14_75080904_-6727-3071.40-3071.40-3089.50
ADediting_451900ENST00000238616.10chr14_75080905_-6726-3071.70-3071.40-3089.50
ADediting_451901ENST00000238616.10chr14_75081082_-6549-3071.10-3071.40-3089.50
ADediting_451902ENST00000238616.10chr14_75081092_-6539-3076.30-3071.40-3089.50
ADediting_451903ENST00000238616.10chr14_75081125_-6506-3071.50-3071.40-3089.50
ADediting_451904ENST00000238616.10chr14_75081128_-6503-3071.40-3071.40-3089.50
ADediting_451905ENST00000238616.10chr14_75081145_-6486-3075.20-3071.40-3089.50
ADediting_451906ENST00000238616.10chr14_75081216_-6415-3071.40-3071.40-3089.50

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_451907ENST00000555763.1chr14_75085089_-7-273.10-270.10-273.10

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Relation with ADAR for NEK9

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_451894chr14_75080709_-0.7869726696402980.01541016038914810.422331687680345-0.04573316934557822.64601983166331e-100.348919591300892
DLPFCADediting_451897chr14_75080841_-0.05663178295304060.1083803215856880.964260546002365-0.002555227665362992.46245395032903e-160.443036083040981
DLPFCADediting_451900chr14_75080905_-0.9650997403147380.002495190060797920.200791118373284-0.07285713581033051.21783764415264e-100.355056114990428
DLPFCADediting_451941chr14_75093539_-0.1342891153599280.08523611837069070.397947534843264-0.04817612610926623.65541820465565e-090.327104766638243
DLPFCADediting_451945chr14_75093592_-0.6095083071536980.02912158616629440.0783253680354283-0.1001419715205952.00237376859321e-160.444236411853669
DLPFCADediting_451946chr14_75093598_-0.3548963874391620.05272048870134640.096808450479764-0.09448220522669611.06736116206964e-230.528454214829268
CERADediting_451963chr14_75094561_-3.76218728193517e-060.3673440467699490.001531648988039030.2565194209207950.5462550153347640.0496508346288898
CERADediting_451964chr14_75094566_-3.75257723599528e-050.3298663540671070.0006812817707125550.2743186103579250.8790078152821980.0125336530213933
DLPFCADediting_451967chr14_75094640_-0.01249239606983450.1417280823711420.686806341751892-0.02298966211494649.94365219148545e-210.496830170849716
DLPFCADediting_451968chr14_75094652_-0.2683129409001840.06306303904422630.162591698770066-0.07950622395029712.75792033233959e-090.329528851290915
DLPFCADediting_451969chr14_75094658_-0.4613496335738410.04198873228363650.0476829267558704-0.1125639108241459.97925358979908e-150.420706680366335
DLPFCADediting_451970chr14_75094668_-0.3586343534362660.0523128393580210.0816044005426123-0.09906458855564642.83538768666588e-160.442214932217501
DLPFCADediting_451971chr14_75094671_-0.6806334589423170.02346883315071850.0863282083658068-0.09757233971219322.13590738283217e-100.350626488305449
DLPFCADediting_451972chr14_75094672_-0.3824511704919620.04977547801872340.101749647427644-0.09311710427143222.47601159347219e-110.367256306417936
DLPFCADediting_451973chr14_75094680_-0.3418605831260020.05416368194439150.388559746712197-0.04914042180362134.1301494731124e-090.326047519952751
DLPFCADediting_451975chr14_75094698_-0.07838153145341410.1001232135036840.712613317398253-0.02100333503520933.48561345911458e-140.412773319506653
DLPFCADediting_451981chr14_75094741_-0.01456534264157120.1386429811057710.4301217080728980.04497023983348762.69982164183329e-080.309254118322834
DLPFCADediting_452038chr14_75123362_-0.16297931485937-0.07943319221765050.00970679268884886-0.1466780776266296.65844661998298e-090.321872896940945

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.38090930069845e-290.582745927595024.12064004654393e-290.5787203123733821.38777304670618e-160.446352626976551
AC1.36182521228067e-420.7282893060120144.06630993653067e-210.5494192331485622.51019051232112e-380.70131935269326
PCC1.05865871136369e-090.4232573802450993.94640360232477e-060.3268027792479925.55282328702011e-160.542079598766803
CER2.74807552531929e-250.7203706513518047.66494503671019e-150.5797129160899260.006733007990694850.220368479587475
TCX1.21853269319494e-090.4706641116922760.896225672238248-0.01073915390078073.69484005245787e-320.781741245836854
FP8.1851049216119e-240.6620199534984341.98721954227417e-210.6343326056408231.15664090321886e-130.518993936013612
IFG0.0003173630329955450.6614834907726590.0007261956333924270.6306347252182923.06908667430405e-050.733084322345276
PG3.44173019555606e-360.7594190067477551.13439518999783e-240.6603999822464780.01506974452132540.178001749264118
STG1.84756878791971e-070.5325379680438144.63042960765866e-050.4291783983072923.18579741455894e-050.437341618166241

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Relation with AD stages for NEK9

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER3.18585904326462e-050.388921742082144
TCX4.89197880594752e-120.607774144912183

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RelatedDrugs for NEK9

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
NEK9Q8TD19DB12010FostamatinibSerine/threonine-protein kinase Nek9small moleculeapproved|investigational

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RelatedDiseases for NEK9

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
NEK9C0003886Arthrogryposis2GENOMICS_ENGLAND
NEK9C0265987Nevus comedonicus1CTD_human;ORPHANET;UNIPROT
NEK9C3280309ARTHROGRYPOSIS, PERTHES DISEASE, AND UPWARD GAZE PALSY1CTD_human;UNIPROT