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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ZNF682

check button Gene summary
Gene informationGene symbol

ZNF682

Gene ID

91120

Gene namezinc finger protein 682
SynonymsBC39498_3
Cytomap

19p12

Type of geneprotein-coding
Descriptionzinc finger protein 682
Modification date20200313
UniProtAcc

O95780,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ZNF682

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_727683(19999698, -), ADediting_727684(19999699, -), ADediting_727685(20002288, -), ADediting_727686(20002298, -), ADediting_727687(20002299, -), ADediting_727688(20005132, -), ADediting_727689(20005147, -), ADediting_727690(20005166, -), ADediting_727691(20005171, -), ADediting_727692(20005186, -), ADediting_727693(20005214, -), ADediting_727694(20005232, -), ADediting_727695(20005247, -), ADediting_727696(20005250, -), ADediting_727697(20005309, -), ADediting_727698(20005330, -), ADediting_727699(20005338, -), ADediting_727700(20009934, -), ADediting_727703(20010902, -), ADediting_727704(20010921, -), ADediting_727706(20011870, -), ADediting_727707(20011881, -), ADediting_727708(20011915, -), ADediting_727709(20011921, -), ADediting_727710(20012023, -), ADediting_727712(20012705, -), ADediting_727714(20013608, -), ADediting_727715(20013653, -), ADediting_727716(20013672, -), ADediting_727717(20013692, -), ADediting_727718(20013701, -), ADediting_727719(20013709, -), ADediting_727720(20013713, -), ADediting_727721(20013718, -), ADediting_727722(20013783, -), ADediting_727723(20013811, -), ADediting_727724(20013826, -), ADediting_727725(20013836, -), ADediting_727726(20013844, -), ADediting_727727(20013852, -), ADediting_727728(20013859, -), ADediting_727729(20013875, -), ADediting_727734(20014515, -), ADediting_727735(20014542, -), ADediting_727736(20014597, -), ADediting_727737(20016060, -), ADediting_727740(20018190, -), ADediting_727741(20018199, -), ADediting_727742(20018226, -), ADediting_727743(20018232, -), ADediting_727753(20021326, -), ADediting_727754(20021349, -), ADediting_727755(20021384, -), ADediting_727756(20021401, -), ADediting_727757(20021408, -), ADediting_727758(20021427, -), ADediting_727759(20021462, -), ADediting_727760(20021470, -), ADediting_727765(20027497, -), ADediting_727766(20027503, -), ADediting_727768(20027556, -), ADediting_727769(20027557, -), ADediting_727770(20027637, -), ADediting_727772(20027676, -), ADediting_727773(20027699, -), ADediting_727774(20028270, -), ADediting_727775(20028284, -), ADediting_727776(20028292, -), ADediting_727777(20028293, -), ADediting_727778(20028297, -), ADediting_727779(20028346, -), ADediting_727780(20028491, -), ADediting_727781(20028503, -), ADediting_727782(20029008, -), ADediting_727783(20029009, -), ADediting_727784(20029090, -), ADediting_727785(20029103, -), ADediting_727786(20029119, -), ADediting_727787(20029143, -), ADediting_727788(20029147, -), ADediting_727789(20029152, -), ADediting_727790(20029192, -), ADediting_727791(20029206, -), ADediting_727792(20029221, -), ADediting_727793(20029254, -), ADediting_727794(20029262, -), ADediting_727795(20029515, -), ADediting_727796(20029524, -), ADediting_727797(20030385, -), ADediting_727798(20033009, -), ADediting_727799(20033204, -), ADediting_727800(20033210, -), ADediting_727801(20033211, -), ADediting_1553908(20005127, -), ADediting_1553909(20005151, -), ADediting_1553910(20005180, -), ADediting_1553911(20005190, -), ADediting_1553912(20005254, -), ADediting_1553913(20009764, -), ADediting_1553914(20009775, -), ADediting_1553915(20010403, -), ADediting_1553916(20010425, -), ADediting_1553917(20011991, -), ADediting_1553919(20013648, -), ADediting_1553920(20014578, -), ADediting_1553921(20016076, -), ADediting_1630962(20016085, -), ADediting_1630963(20016093, -), ADediting_1630964(20027857, -), ADediting_1630965(20034613, -), ADediting_1630966(20034616, -),

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RNA editing positional annotations for ZNF682 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_727683chr19_19999698_-intronic
ADediting_727684chr19_19999699_-intronic
ADediting_727685chr19_20002288_-intronic
ADediting_727686chr19_20002298_-intronic
ADediting_727687chr19_20002299_-intronic
ADediting_727688chr19_20005132_-UTR3
ADediting_727689chr19_20005147_-UTR3
ADediting_727690chr19_20005166_-UTR3
ADediting_727691chr19_20005171_-UTR3
ADediting_727692chr19_20005186_-UTR3
ADediting_727693chr19_20005214_-UTR3
ADediting_727694chr19_20005232_-UTR3
ADediting_727695chr19_20005247_-UTR3
ADediting_727696chr19_20005250_-UTR3
ADediting_727697chr19_20005309_-UTR3
ADediting_727698chr19_20005330_-UTR3
ADediting_727699chr19_20005338_-UTR3
ADediting_727700chr19_20009934_-intronic
ADediting_727703chr19_20010902_-intronic
ADediting_727704chr19_20010921_-intronic
ADediting_727706chr19_20011870_-intronic
ADediting_727707chr19_20011881_-intronic
ADediting_727708chr19_20011915_-intronic
ADediting_727709chr19_20011921_-intronic
ADediting_727710chr19_20012023_-intronic
ADediting_727712chr19_20012705_-intronic
ADediting_727714chr19_20013608_-intronic
ADediting_727715chr19_20013653_-intronic
ADediting_727716chr19_20013672_-intronic
ADediting_727717chr19_20013692_-intronic
ADediting_727718chr19_20013701_-intronic
ADediting_727719chr19_20013709_-intronic
ADediting_727720chr19_20013713_-intronic
ADediting_727721chr19_20013718_-intronic
ADediting_727722chr19_20013783_-intronic
ADediting_727723chr19_20013811_-intronic
ADediting_727724chr19_20013826_-intronic
ADediting_727725chr19_20013836_-intronic
ADediting_727726chr19_20013844_-intronic
ADediting_727727chr19_20013852_-intronic
ADediting_727728chr19_20013859_-intronic
ADediting_727729chr19_20013875_-intronic
ADediting_727734chr19_20014515_-intronic
ADediting_727735chr19_20014542_-intronic
ADediting_727736chr19_20014597_-intronic
ADediting_727737chr19_20016060_-intronic
ADediting_727740chr19_20018190_-intronic
ADediting_727741chr19_20018199_-intronic
ADediting_727742chr19_20018226_-intronic
ADediting_727743chr19_20018232_-intronic
ADediting_727753chr19_20021326_-intronic
ADediting_727754chr19_20021349_-intronic
ADediting_727755chr19_20021384_-intronic
ADediting_727756chr19_20021401_-intronic
ADediting_727757chr19_20021408_-intronic
ADediting_727758chr19_20021427_-intronic
ADediting_727759chr19_20021462_-intronic
ADediting_727760chr19_20021470_-intronic
ADediting_727765chr19_20027497_-intronic
ADediting_727766chr19_20027503_-intronic
ADediting_727768chr19_20027556_-intronic
ADediting_727769chr19_20027557_-intronic
ADediting_727770chr19_20027637_-intronic
ADediting_727772chr19_20027676_-intronic
ADediting_727773chr19_20027699_-intronic
ADediting_727774chr19_20028270_-intronic
ADediting_727775chr19_20028284_-intronic
ADediting_727776chr19_20028292_-intronic
ADediting_727777chr19_20028293_-intronic
ADediting_727778chr19_20028297_-intronic
ADediting_727779chr19_20028346_-intronic
ADediting_727780chr19_20028491_-intronic
ADediting_727781chr19_20028503_-intronic
ADediting_727782chr19_20029008_-intronic
ADediting_727783chr19_20029009_-intronic
ADediting_727784chr19_20029090_-intronic
ADediting_727785chr19_20029103_-intronic
ADediting_727786chr19_20029119_-intronic
ADediting_727787chr19_20029143_-intronic
ADediting_727788chr19_20029147_-intronic
ADediting_727789chr19_20029152_-intronic
ADediting_727790chr19_20029192_-intronic
ADediting_727791chr19_20029206_-intronic
ADediting_727792chr19_20029221_-intronic
ADediting_727793chr19_20029254_-intronic
ADediting_727794chr19_20029262_-intronic
ADediting_727795chr19_20029515_-intronic
ADediting_727796chr19_20029524_-intronic
ADediting_727797chr19_20030385_-intronic
ADediting_727798chr19_20033009_-intronic
ADediting_727799chr19_20033204_-intronic
ADediting_727800chr19_20033210_-intronic
ADediting_727801chr19_20033211_-intronic
ADediting_1553908chr19_20005127_-UTR3
ADediting_1553909chr19_20005151_-UTR3
ADediting_1553910chr19_20005180_-UTR3
ADediting_1553911chr19_20005190_-UTR3
ADediting_1553912chr19_20005254_-UTR3
ADediting_1553913chr19_20009764_-intronic
ADediting_1553914chr19_20009775_-intronic
ADediting_1553915chr19_20010403_-intronic
ADediting_1553916chr19_20010425_-intronic
ADediting_1553917chr19_20011991_-intronic
ADediting_1553919chr19_20013648_-intronic
ADediting_1553920chr19_20014578_-intronic
ADediting_1553921chr19_20016076_-intronic
ADediting_1630962chr19_20016085_-intronic
ADediting_1630963chr19_20016093_-intronic
ADediting_1630964chr19_20027857_-intronic
ADediting_1630965chr19_20034613_-intronic
ADediting_1630966chr19_20034616_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_727683chr19_19999698_-SINEAluName=AluSz
ADediting_727684chr19_19999699_-SINEAluName=AluSz
ADediting_727685chr19_20002288_-SINEAluName=AluSc8
ADediting_727686chr19_20002298_-SINEAluName=AluSc8
ADediting_727687chr19_20002299_-SINEAluName=AluSc8
ADediting_727688chr19_20005132_-SINEAluName=AluYc3
ADediting_727689chr19_20005147_-SINEAluName=AluYc3
ADediting_727690chr19_20005166_-SINEAluName=AluYc3
ADediting_727691chr19_20005171_-SINEAluName=AluYc3
ADediting_727692chr19_20005186_-SINEAluName=AluYc3
ADediting_727693chr19_20005214_-SINEAluName=AluYc3
ADediting_727694chr19_20005232_-SINEAluName=AluYc3
ADediting_727695chr19_20005247_-SINEAluName=AluYc3
ADediting_727696chr19_20005250_-SINEAluName=AluYc3
ADediting_727697chr19_20005309_-SINEAluName=AluYc3
ADediting_727698chr19_20005330_-SINEAluName=AluYc3
ADediting_727699chr19_20005338_-SINEAluName=AluYc3
ADediting_727700chr19_20009934_-SINEAluName=AluSx
ADediting_727703chr19_20010902_-SINEAluName=AluSc
ADediting_727704chr19_20010921_-SINEAluName=AluSc
ADediting_727706chr19_20011870_-SINEAluName=AluSx3
ADediting_727707chr19_20011881_-SINEAluName=AluSx3
ADediting_727708chr19_20011915_-SINEAluName=AluSx3
ADediting_727709chr19_20011921_-SINEAluName=AluSx3
ADediting_727710chr19_20012023_-SINEAluName=AluSx3
ADediting_727712chr19_20012705_-SINEAluName=AluY
ADediting_727714chr19_20013608_-SINEAluName=AluSp
ADediting_727715chr19_20013653_-SINEAluName=AluSp
ADediting_727716chr19_20013672_-SINEAluName=AluSp
ADediting_727717chr19_20013692_-SINEAluName=AluSp
ADediting_727718chr19_20013701_-SINEAluName=AluSp
ADediting_727719chr19_20013709_-SINEAluName=AluSp
ADediting_727720chr19_20013713_-SINEAluName=AluSp
ADediting_727721chr19_20013718_-SINEAluName=AluSp
ADediting_727722chr19_20013783_-SINEAluName=AluSp
ADediting_727723chr19_20013811_-SINEAluName=AluSp
ADediting_727724chr19_20013826_-SINEAluName=AluSp
ADediting_727725chr19_20013836_-SINEAluName=AluSp
ADediting_727726chr19_20013844_-SINEAluName=AluSp
ADediting_727727chr19_20013852_-SINEAluName=AluSp
ADediting_727728chr19_20013859_-SINEAluName=AluSp
ADediting_727729chr19_20013875_-SINEAluName=AluSp
ADediting_727734chr19_20014515_-SINEAluName=AluSc
ADediting_727735chr19_20014542_-SINEAluName=AluSc
ADediting_727736chr19_20014597_-SINEAluName=AluSc
ADediting_727737chr19_20016060_-SINEAluName=AluJb
ADediting_727740chr19_20018190_-SINEAluName=AluYa5
ADediting_727741chr19_20018199_-SINEAluName=AluYa5
ADediting_727742chr19_20018226_-SINEAluName=AluYa5
ADediting_727743chr19_20018232_-SINEAluName=AluYa5
ADediting_727753chr19_20021326_-SINEAluName=AluSx
ADediting_727754chr19_20021349_-SINEAluName=AluSx
ADediting_727755chr19_20021384_-SINEAluName=AluSx
ADediting_727756chr19_20021401_-SINEAluName=AluSx
ADediting_727757chr19_20021408_-SINEAluName=AluSx
ADediting_727758chr19_20021427_-SINEAluName=AluSx
ADediting_727759chr19_20021462_-SINEAluName=AluSx
ADediting_727760chr19_20021470_-SINEAluName=AluSx
ADediting_727765chr19_20027497_-SINEAluName=AluSp
ADediting_727766chr19_20027503_-SINEAluName=AluSp
ADediting_727768chr19_20027556_-SINEAluName=AluSp
ADediting_727769chr19_20027557_-SINEAluName=AluSp
ADediting_727770chr19_20027637_-SINEAluName=AluSp
ADediting_727772chr19_20027676_-SINEAluName=AluSp
ADediting_727773chr19_20027699_-SINEAluName=AluSp
ADediting_727774chr19_20028270_-SINEAluName=AluSx
ADediting_727775chr19_20028284_-SINEAluName=AluSx
ADediting_727776chr19_20028292_-SINEAluName=AluSx
ADediting_727777chr19_20028293_-SINEAluName=AluSx
ADediting_727778chr19_20028297_-SINEAluName=AluSx
ADediting_727779chr19_20028346_-SINEAluName=AluSx
ADediting_727780chr19_20028491_-SINEAluName=AluSx
ADediting_727781chr19_20028503_-SINEAluName=AluSx
ADediting_727782chr19_20029008_-SINEAluName=AluSx1
ADediting_727783chr19_20029009_-SINEAluName=AluSx1
ADediting_727784chr19_20029090_-SINEAluName=AluSx1
ADediting_727785chr19_20029103_-SINEAluName=AluSx1
ADediting_727786chr19_20029119_-SINEAluName=AluSx1
ADediting_727787chr19_20029143_-SINEAluName=AluSx1
ADediting_727788chr19_20029147_-SINEAluName=AluSx1
ADediting_727789chr19_20029152_-SINEAluName=AluSx1
ADediting_727790chr19_20029192_-SINEAluName=AluSx1
ADediting_727791chr19_20029206_-SINEAluName=AluSx1
ADediting_727792chr19_20029221_-SINEAluName=AluSx1
ADediting_727793chr19_20029254_-SINEAluName=AluSx1
ADediting_727794chr19_20029262_-SINEAluName=AluSx1
ADediting_727795chr19_20029515_-SINEAluName=AluSx
ADediting_727796chr19_20029524_-SINEAluName=AluSx
ADediting_727797chr19_20030385_-SINEAluName=AluSx
ADediting_727798chr19_20033009_-SINEAluName=AluSx1
ADediting_727799chr19_20033204_-SINEAluName=AluSx1
ADediting_727800chr19_20033210_-SINEAluName=AluSx1
ADediting_727801chr19_20033211_-SINEAluName=AluSx1
ADediting_1553908chr19_20005127_-SINEAluName=AluYc3
ADediting_1553909chr19_20005151_-SINEAluName=AluYc3
ADediting_1553910chr19_20005180_-SINEAluName=AluYc3
ADediting_1553911chr19_20005190_-SINEAluName=AluYc3
ADediting_1553912chr19_20005254_-SINEAluName=AluYc3
ADediting_1553913chr19_20009764_-SINEAluName=AluSx
ADediting_1553914chr19_20009775_-SINEAluName=AluSx
ADediting_1553915chr19_20010403_-SINEAluName=AluSx
ADediting_1553916chr19_20010425_-SINEAluName=AluSx
ADediting_1553917chr19_20011991_-SINEAluName=AluSx3
ADediting_1553919chr19_20013648_-SINEAluName=AluSp
ADediting_1553920chr19_20014578_-SINEAluName=AluSc
ADediting_1553921chr19_20016076_-SINEAluName=AluJb
ADediting_1630962chr19_20016085_-SINEAluName=AluJb
ADediting_1630963chr19_20016093_-SINEAluName=AluJb
ADediting_1630964chr19_20027857_-SINEAluName=AluSx3
ADediting_1630965chr19_20034613_-SINEAluName=AluSp
ADediting_1630966chr19_20034616_-SINEAluName=AluSp

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RNA A-to-I editing events in the alternative splicing sites for ZNF682

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF682

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ZNF682

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ZNF682

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-3670chr1920005124200051307mer-m82000512320005145152-16.52
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6854-5pchr1920005125200051317mer-m82000512420005149153-17.47
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6874-5pchr1920005121200051288mer-1a2000512120005145142-17.6
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-3670chr1920005124200051307mer-m82000512320005145152-16.52
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6854-5pchr1920005125200051317mer-m82000512420005149153-17.47
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6874-5pchr1920005121200051288mer-1a2000512120005145142-17.6
ADediting_1553910chr19_20005180_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4639-3pchr1920005178200051847mer-m82000517720005199148-23.17
ADediting_1553910chr19_20005180_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6777-3pchr1920005177200051837mer-m82000517620005195164-29.74
ADediting_1553910chr19_20005180_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4639-3pchr1920005178200051847mer-m82000517720005199148-23.17
ADediting_1553910chr19_20005180_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6777-3pchr1920005177200051837mer-m82000517620005195164-29.74
ADediting_1553911chr19_20005190_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-1913chr1920005185200051917mer-m82000518420005205155-27.23
ADediting_1553911chr19_20005190_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6849-3pchr1920005190200051967mer-m82000518920005209149-20.24
ADediting_1553911chr19_20005190_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-1913chr1920005185200051917mer-m82000518420005205155-27.23
ADediting_1553911chr19_20005190_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6849-3pchr1920005190200051967mer-m82000518920005209149-20.24
ADediting_1553912chr19_20005254_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-630chr1920005248200052558mer-1a2000524820005269157-16.15
ADediting_1553912chr19_20005254_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-630chr1920005248200052558mer-1a2000524820005269157-16.15
ADediting_727689chr19_20005147_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-324-3pchr1920005147200051537mer-m82000514620005165149-24.83
ADediting_727689chr19_20005147_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6075chr1920005142200051498mer-1a2000514220005164144-23.87
ADediting_727689chr19_20005147_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-324-3pchr1920005147200051537mer-m82000514620005165149-24.83
ADediting_727689chr19_20005147_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6075chr1920005142200051498mer-1a2000514220005164144-23.87
ADediting_727690chr19_20005166_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6778-3pchr1920005161200051677mer-m82000516020005182149-21.76
ADediting_727690chr19_20005166_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6778-3pchr1920005161200051677mer-m82000516020005182149-21.76
ADediting_727691chr19_20005171_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-3944-3pchr1920005166200051727mer-m82000516520005187157-26.46
ADediting_727691chr19_20005171_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4284chr1920005169200051757mer-m82000516820005185148-20.34
ADediting_727691chr19_20005171_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4437chr1920005168200051747mer-m82000516720005187145-18.43
ADediting_727691chr19_20005171_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-3944-3pchr1920005166200051727mer-m82000516520005187157-26.46
ADediting_727691chr19_20005171_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4284chr1920005169200051757mer-m82000516820005185148-20.34
ADediting_727691chr19_20005171_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4437chr1920005168200051747mer-m82000516720005187145-18.43
ADediting_727693chr19_20005214_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-140-3pchr1920005212200052187mer-m82000521120005232146-21.91
ADediting_727693chr19_20005214_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-140-3pchr1920005212200052187mer-m82000521120005232146-21.91
ADediting_727695chr19_20005247_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4742-3pchr1920005246200052538mer-1a2000524620005268142-10.99
ADediting_727695chr19_20005247_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4742-3pchr1920005246200052538mer-1a2000524620005268142-10.99
ADediting_727696chr19_20005250_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-153-5pchr1920005250200052567mer-m82000524920005269146-9.95
ADediting_727696chr19_20005250_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-3680-3pchr1920005245200052528mer-1a2000524520005267140-13.99
ADediting_727696chr19_20005250_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-153-5pchr1920005250200052567mer-m82000524920005269146-9.95
ADediting_727696chr19_20005250_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-3680-3pchr1920005245200052528mer-1a2000524520005267140-13.99
ADediting_727697chr19_20005309_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4707-3pchr1920005306200053127mer-m82000530520005326154-23.87
ADediting_727697chr19_20005309_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4707-3pchr1920005306200053127mer-m82000530520005326154-23.87
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-371a-3pchr1920005325200053317mer-m82000532420005344154-20.42
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-371a-3pchr1920005325200053317mer-m82000532420005344154-20.42
ADediting_727699chr19_20005338_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6513-3pchr1920005338200053447mer-m82000533720005357154-15.46
ADediting_727699chr19_20005338_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6513-3pchr1920005338200053447mer-m82000533720005357154-15.46

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-5000-5pchr1920005125200051317mer-m82000512420005145146-14.52
ADediting_1553908chr19_20005127_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-5000-5pchr1920005125200051317mer-m82000512420005145146-14.52
ADediting_1553909chr19_20005151_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-2276-3pchr1920005150200051567mer-m82000514920005170144-18.15
ADediting_1553909chr19_20005151_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-2276-3pchr1920005150200051567mer-m82000514920005170144-18.15
ADediting_727688chr19_20005132_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-5693chr1920005128200051358mer-1a2000512820005148143-16.55
ADediting_727688chr19_20005132_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-5693chr1920005128200051358mer-1a2000512820005148143-16.55
ADediting_727689chr19_20005147_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4284chr1920005144200051507mer-m82000514320005160144-13.03
ADediting_727689chr19_20005147_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4284chr1920005144200051507mer-m82000514320005160144-13.03
ADediting_727692chr19_20005186_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-1976chr1920005181200051888mer-1a2000518120005202149-20.79
ADediting_727692chr19_20005186_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6747-3pchr1920005183200051908mer-1a2000518320005205155-31.9
ADediting_727692chr19_20005186_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-1976chr1920005181200051888mer-1a2000518120005202149-20.79
ADediting_727692chr19_20005186_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6747-3pchr1920005183200051908mer-1a2000518320005205155-31.9
ADediting_727693chr19_20005214_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-7151-3pchr1920005214200052207mer-m82000521320005237141-23
ADediting_727693chr19_20005214_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-8052chr1920005208200052147mer-1a2000520820005228142-22.21
ADediting_727693chr19_20005214_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-7151-3pchr1920005214200052207mer-m82000521320005237141-23
ADediting_727693chr19_20005214_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-8052chr1920005208200052147mer-1a2000520820005228142-22.21
ADediting_727697chr19_20005309_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-4485-5pchr1920005303200053108mer-1a2000530320005318150-22.24
ADediting_727697chr19_20005309_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6747-3pchr1920005307200053137mer-m82000530620005327150-22.04
ADediting_727697chr19_20005309_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-4485-5pchr1920005303200053108mer-1a2000530320005318150-22.24
ADediting_727697chr19_20005309_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6747-3pchr1920005307200053137mer-m82000530620005327150-22.04
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-5089-5pchr1920005330200053367mer-m82000532920005348149-14.93
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-512-3pchr1920005325200053317mer-m82000532420005348151-16.23
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397162.5ZNF682-202hsa-miR-6506-5pchr1920005329200053357mer-m82000532820005351146-14.44
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-5089-5pchr1920005330200053367mer-m82000532920005348149-14.93
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-512-3pchr1920005325200053317mer-m82000532420005348151-16.23
ADediting_727698chr19_20005330_-ENSG00000197124.12ENST00000397165.7ZNF682-203hsa-miR-6506-5pchr1920005329200053357mer-m82000532820005351146-14.44

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF682

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000397162.5protein_codingSoverviewSoverview
ENST00000397165.7protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_1553908ENST00000397162.5chr19_20005127_-2455-756.10-751.80-770.20
ADediting_727688ENST00000397162.5chr19_20005132_-2450-751.40-751.80-770.20
ADediting_727689ENST00000397162.5chr19_20005147_-2435-753.10-751.80-770.20
ADediting_1553909ENST00000397162.5chr19_20005151_-2431-751.10-751.80-770.20
ADediting_727690ENST00000397162.5chr19_20005166_-2416-752.80-751.80-770.20
ADediting_727691ENST00000397162.5chr19_20005171_-2411-758.50-751.80-770.20
ADediting_1553910ENST00000397162.5chr19_20005180_-2402-754.80-751.80-770.20
ADediting_727692ENST00000397162.5chr19_20005186_-2396-751.40-751.80-770.20
ADediting_1553911ENST00000397162.5chr19_20005190_-2392-752.00-751.80-770.20
ADediting_727693ENST00000397162.5chr19_20005214_-2368-751.80-751.80-770.20
ADediting_727694ENST00000397162.5chr19_20005232_-2350-753.20-751.80-770.20
ADediting_727695ENST00000397162.5chr19_20005247_-2335-752.50-751.80-770.20
ADediting_727696ENST00000397162.5chr19_20005250_-2332-751.80-751.80-770.20
ADediting_1553912ENST00000397162.5chr19_20005254_-2328-752.80-751.80-770.20
ADediting_727697ENST00000397162.5chr19_20005309_-2273-751.10-751.80-770.20
ADediting_727698ENST00000397162.5chr19_20005330_-2252-751.70-751.80-770.20
ADediting_727699ENST00000397162.5chr19_20005338_-2244-751.80-751.80-770.20
ADediting_1553908ENST00000397165.7chr19_20005127_-2535-777.00-772.70-798.10
ADediting_727688ENST00000397165.7chr19_20005132_-2530-772.30-772.70-798.10
ADediting_727689ENST00000397165.7chr19_20005147_-2515-774.00-772.70-798.10
ADediting_1553909ENST00000397165.7chr19_20005151_-2511-772.00-772.70-798.10
ADediting_727690ENST00000397165.7chr19_20005166_-2496-773.00-772.70-798.10
ADediting_727691ENST00000397165.7chr19_20005171_-2491-779.40-772.70-798.10
ADediting_1553910ENST00000397165.7chr19_20005180_-2482-775.60-772.70-798.10
ADediting_727692ENST00000397165.7chr19_20005186_-2476-773.40-772.70-798.10
ADediting_1553911ENST00000397165.7chr19_20005190_-2472-774.20-772.70-798.10
ADediting_727693ENST00000397165.7chr19_20005214_-2448-772.70-772.70-798.10
ADediting_727694ENST00000397165.7chr19_20005232_-2430-773.70-772.70-798.10
ADediting_727695ENST00000397165.7chr19_20005247_-2415-773.40-772.70-798.10
ADediting_727696ENST00000397165.7chr19_20005250_-2412-772.70-772.70-798.10
ADediting_1553912ENST00000397165.7chr19_20005254_-2408-773.70-772.70-798.10
ADediting_727697ENST00000397165.7chr19_20005309_-2353-772.00-772.70-798.10
ADediting_727698ENST00000397165.7chr19_20005330_-2332-772.60-772.70-798.10
ADediting_727699ENST00000397165.7chr19_20005338_-2324-772.70-772.70-798.10

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZNF682

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_727743chr19_20018232_-0.964573594887001-0.002532831209049710.165561017351961-0.07895006158350341.12913116601053e-100.355647190957652

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC6.11910865074033e-090.3226159150966846.606395147423e-140.4086351914477558.1302217254661e-060.250372861104123
AC8.40481711473523e-460.746651018414822.67027893250494e-360.6873451087702194.13192980086437e-220.5608089611403
PCC3.41005983367642e-180.5748874422839076.65552275705024e-190.5846856835291470.0001613635056734790.269691651633732
FP3.8492942667265e-210.6307995960864818.231048554645e-180.586193982489720.03809060462815890.155591990243943
IFG0.02325587492827760.4521462415645530.07336324546650330.364341128191230.8105815456929430.0504895384907328
PG5.94148316286061e-300.7110218521466381.01068214398221e-240.6609316377661530.843106253658997-0.0146100461134669
STG9.82468328961346e-100.6063255234466741.16564271348521e-060.5016800846181560.4388526593465730.0855920713319539

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Relation with AD stages for ZNF682

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for ZNF682

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF682

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource