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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ZNF551 |
 Gene summary |
| Gene information | Gene symbol | ZNF551 | Gene ID | 90233 |
| Gene name | zinc finger protein 551 | |
| Synonyms | - | |
| Cytomap | 19q13.43 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein 551KOX 23 protein (56 AA)zinc finger protein KOX23 | |
| Modification date | 20200313 | |
| UniProtAcc | Q7Z340, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ZNF551 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_785708(57685299, +), ADediting_785709(57685300, +), ADediting_785710(57685303, +), ADediting_785711(57685329, +), ADediting_785712(57685341, +), ADediting_785713(57686575, +), ADediting_785714(57689513, +), ADediting_785715(57689597, +), ADediting_785716(57689881, +), ADediting_785717(57689963, +), ADediting_785718(57689966, +), ADediting_785719(57690020, +), ADediting_785720(57691182, +), ADediting_785721(57691251, +), ADediting_785722(57691351, +), ADediting_785723(57691481, +), ADediting_785724(57691503, +), ADediting_785725(57691513, +), ADediting_785726(57691812, +), ADediting_785727(57691884, +), ADediting_785728(57693235, +), ADediting_785729(57693243, +), ADediting_785730(57693376, +), ADediting_785731(57693412, +), ADediting_785732(57693418, +), ADediting_785733(57693436, +), ADediting_785734(57693439, +), ADediting_785735(57694975, +), ADediting_785736(57695014, +), ADediting_785737(57695067, +), ADediting_785738(57695077, +), ADediting_785739(57695082, +), ADediting_785740(57695088, +), ADediting_785741(57695091, +), ADediting_785742(57695106, +), ADediting_785743(57695132, +), ADediting_785744(57695133, +), ADediting_785745(57695142, +), ADediting_785746(57695355, +), ADediting_785747(57695365, +), ADediting_785748(57695391, +), ADediting_785749(57695392, +), ADediting_785750(57695406, +), ADediting_785751(57695411, +), ADediting_785752(57695415, +), ADediting_785753(57695461, +), ADediting_785754(57695487, +), ADediting_785755(57695488, +), ADediting_785756(57695500, +), ADediting_785757(57695602, +), ADediting_785758(57695607, +), ADediting_785759(57697300, +), ADediting_785760(57709760, +), ADediting_785761(57709813, +), ADediting_785762(57709820, +), ADediting_785763(57709824, +), ADediting_785764(57709834, +), ADediting_785765(57709860, +), ADediting_785766(57709870, +), ADediting_785767(57709896, +), ADediting_785768(57713685, +), ADediting_785769(57713701, +), ADediting_785770(57713711, +), ADediting_785771(57713712, +), ADediting_785772(57713769, +), ADediting_785773(57713771, +), ADediting_785774(57713779, +), ADediting_785775(57713869, +), ADediting_785776(57713886, +), ADediting_785777(57713896, +), ADediting_785778(57714302, +), ADediting_785779(57714303, +), ADediting_785780(57714311, +), ADediting_785781(57714383, +), ADediting_785782(57714393, +), ADediting_785783(57714411, +), ADediting_785784(57714435, +), ADediting_785785(57714447, +), ADediting_785786(57715176, +), ADediting_785787(57715206, +), ADediting_785788(57715236, +), ADediting_785789(57715237, +), ADediting_785790(57715251, +), ADediting_785791(57715252, +), ADediting_785792(57715383, +), ADediting_785793(57715384, +), ADediting_785794(57715413, +), ADediting_785795(57716215, +), ADediting_785796(57716248, +), ADediting_785797(57716254, +), ADediting_785798(57716300, +), ADediting_785799(57716364, +), ADediting_1559353(57685286, +), ADediting_1559354(57685323, +), ADediting_1559355(57688914, +), ADediting_1559356(57689598, +), ADediting_1559357(57691500, +), ADediting_1559358(57691536, +), ADediting_1559359(57691552, +), ADediting_1559360(57692406, +), ADediting_1559361(57713219, +), ADediting_1559362(57714308, +), ADediting_1559363(57714310, +), ADediting_1559364(57715220, +), ADediting_1631718(57689634, +), |
Top |
RNA editing positional annotations for ZNF551 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_1559353 | chr19_57685286_+ | nonsynonymous SNV | ENST00000282296.10 | c.A106G | p.I36V | . | 0.025 | . |
| ADediting_1559353 | chr19_57685286_+ | nonsynonymous SNV | ENST00000601064.1 | c.A22G | p.I8V | . | 0.025 | . |
| ADediting_1559353 | chr19_57685286_+ | nonsynonymous SNV | ENST00000596085.1 | c.A58G | p.I20V | . | 0.025 | . |
| ADediting_1559354 | chr19_57685323_+ | nonsynonymous SNV | ENST00000282296.10 | c.A143G | p.E48G | . | 0.844 | . |
| ADediting_1559354 | chr19_57685323_+ | nonsynonymous SNV | ENST00000601064.1 | c.A59G | p.E20G | . | 0.844 | . |
| ADediting_1559354 | chr19_57685323_+ | nonsynonymous SNV | ENST00000596085.1 | c.A95G | p.E32G | . | 0.844 | . |
| ADediting_785708 | chr19_57685299_+ | nonsynonymous SNV | ENST00000282296.10 | c.A119G | p.Q40R | . | 0.123 | . |
| ADediting_785708 | chr19_57685299_+ | nonsynonymous SNV | ENST00000601064.1 | c.A35G | p.Q12R | . | 0.123 | . |
| ADediting_785708 | chr19_57685299_+ | nonsynonymous SNV | ENST00000596085.1 | c.A71G | p.Q24R | . | 0.123 | . |
| ADediting_785709 | chr19_57685300_+ | synonymous SNV | ENST00000282296.10 | c.A120G | p.Q40Q | . | . | . |
| ADediting_785709 | chr19_57685300_+ | synonymous SNV | ENST00000601064.1 | c.A36G | p.Q12Q | . | . | . |
| ADediting_785709 | chr19_57685300_+ | synonymous SNV | ENST00000596085.1 | c.A72G | p.Q24Q | . | . | . |
| ADediting_785710 | chr19_57685303_+ | synonymous SNV | ENST00000282296.10 | c.A123G | p.E41E | . | . | . |
| ADediting_785710 | chr19_57685303_+ | synonymous SNV | ENST00000601064.1 | c.A39G | p.E13E | . | . | . |
| ADediting_785710 | chr19_57685303_+ | synonymous SNV | ENST00000596085.1 | c.A75G | p.E25E | . | . | . |
| ADediting_785711 | chr19_57685329_+ | nonsynonymous SNV | ENST00000282296.10 | c.A149G | p.Q50R | . | 1.0 | . |
| ADediting_785711 | chr19_57685329_+ | nonsynonymous SNV | ENST00000601064.1 | c.A65G | p.Q22R | . | 1.0 | . |
| ADediting_785711 | chr19_57685329_+ | nonsynonymous SNV | ENST00000596085.1 | c.A101G | p.Q34R | . | 1.0 | . |
| ADediting_785712 | chr19_57685341_+ | nonsynonymous SNV | ENST00000282296.10 | c.A161G | p.Y54C | 1.0 | 1.0 | 5.83 |
| ADediting_785712 | chr19_57685341_+ | nonsynonymous SNV | ENST00000601064.1 | c.A77G | p.Y26C | 1.0 | 1.0 | 5.83 |
| ADediting_785712 | chr19_57685341_+ | nonsynonymous SNV | ENST00000596085.1 | c.A113G | p.Y38C | 1.0 | 1.0 | 5.83 |
| ADediting_785713 | chr19_57686575_+ | synonymous SNV | ENST00000282296.10 | c.A300G | p.K100K | . | . | . |
| ADediting_785713 | chr19_57686575_+ | synonymous SNV | ENST00000601064.1 | c.A216G | p.K72K | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_785708 | chr19_57685299_+ | exonic |
| ADediting_785709 | chr19_57685300_+ | exonic |
| ADediting_785710 | chr19_57685303_+ | exonic |
| ADediting_785711 | chr19_57685329_+ | exonic |
| ADediting_785712 | chr19_57685341_+ | exonic |
| ADediting_785713 | chr19_57686575_+ | exonic |
| ADediting_785714 | chr19_57689513_+ | UTR3 |
| ADediting_785715 | chr19_57689597_+ | UTR3 |
| ADediting_785716 | chr19_57689881_+ | UTR3 |
| ADediting_785717 | chr19_57689963_+ | UTR3 |
| ADediting_785718 | chr19_57689966_+ | UTR3 |
| ADediting_785719 | chr19_57690020_+ | UTR3 |
| ADediting_785720 | chr19_57691182_+ | intronic |
| ADediting_785721 | chr19_57691251_+ | intronic |
| ADediting_785722 | chr19_57691351_+ | intronic |
| ADediting_785723 | chr19_57691481_+ | intronic |
| ADediting_785724 | chr19_57691503_+ | intronic |
| ADediting_785725 | chr19_57691513_+ | intronic |
| ADediting_785726 | chr19_57691812_+ | intronic |
| ADediting_785727 | chr19_57691884_+ | intronic |
| ADediting_785728 | chr19_57693235_+ | intronic |
| ADediting_785729 | chr19_57693243_+ | intronic |
| ADediting_785730 | chr19_57693376_+ | intronic |
| ADediting_785731 | chr19_57693412_+ | intronic |
| ADediting_785732 | chr19_57693418_+ | intronic |
| ADediting_785733 | chr19_57693436_+ | intronic |
| ADediting_785734 | chr19_57693439_+ | intronic |
| ADediting_785735 | chr19_57694975_+ | intronic |
| ADediting_785736 | chr19_57695014_+ | intronic |
| ADediting_785737 | chr19_57695067_+ | intronic |
| ADediting_785738 | chr19_57695077_+ | intronic |
| ADediting_785739 | chr19_57695082_+ | intronic |
| ADediting_785740 | chr19_57695088_+ | intronic |
| ADediting_785741 | chr19_57695091_+ | intronic |
| ADediting_785742 | chr19_57695106_+ | intronic |
| ADediting_785743 | chr19_57695132_+ | intronic |
| ADediting_785744 | chr19_57695133_+ | intronic |
| ADediting_785745 | chr19_57695142_+ | intronic |
| ADediting_785746 | chr19_57695355_+ | intronic |
| ADediting_785747 | chr19_57695365_+ | intronic |
| ADediting_785748 | chr19_57695391_+ | intronic |
| ADediting_785749 | chr19_57695392_+ | intronic |
| ADediting_785750 | chr19_57695406_+ | intronic |
| ADediting_785751 | chr19_57695411_+ | intronic |
| ADediting_785752 | chr19_57695415_+ | intronic |
| ADediting_785753 | chr19_57695461_+ | intronic |
| ADediting_785754 | chr19_57695487_+ | intronic |
| ADediting_785755 | chr19_57695488_+ | intronic |
| ADediting_785756 | chr19_57695500_+ | intronic |
| ADediting_785757 | chr19_57695602_+ | intronic |
| ADediting_785758 | chr19_57695607_+ | intronic |
| ADediting_785759 | chr19_57697300_+ | intronic |
| ADediting_785760 | chr19_57709760_+ | intronic |
| ADediting_785761 | chr19_57709813_+ | intronic |
| ADediting_785762 | chr19_57709820_+ | intronic |
| ADediting_785763 | chr19_57709824_+ | intronic |
| ADediting_785764 | chr19_57709834_+ | intronic |
| ADediting_785765 | chr19_57709860_+ | intronic |
| ADediting_785766 | chr19_57709870_+ | intronic |
| ADediting_785767 | chr19_57709896_+ | intronic |
| ADediting_785768 | chr19_57713685_+ | intronic |
| ADediting_785769 | chr19_57713701_+ | intronic |
| ADediting_785770 | chr19_57713711_+ | intronic |
| ADediting_785771 | chr19_57713712_+ | intronic |
| ADediting_785772 | chr19_57713769_+ | intronic |
| ADediting_785773 | chr19_57713771_+ | intronic |
| ADediting_785774 | chr19_57713779_+ | intronic |
| ADediting_785775 | chr19_57713869_+ | intronic |
| ADediting_785776 | chr19_57713886_+ | intronic |
| ADediting_785777 | chr19_57713896_+ | intronic |
| ADediting_785778 | chr19_57714302_+ | intronic |
| ADediting_785779 | chr19_57714303_+ | intronic |
| ADediting_785780 | chr19_57714311_+ | intronic |
| ADediting_785781 | chr19_57714383_+ | intronic |
| ADediting_785782 | chr19_57714393_+ | intronic |
| ADediting_785783 | chr19_57714411_+ | intronic |
| ADediting_785784 | chr19_57714435_+ | intronic |
| ADediting_785785 | chr19_57714447_+ | intronic |
| ADediting_785786 | chr19_57715176_+ | intronic |
| ADediting_785787 | chr19_57715206_+ | intronic |
| ADediting_785788 | chr19_57715236_+ | intronic |
| ADediting_785789 | chr19_57715237_+ | intronic |
| ADediting_785790 | chr19_57715251_+ | intronic |
| ADediting_785791 | chr19_57715252_+ | intronic |
| ADediting_785792 | chr19_57715383_+ | intronic |
| ADediting_785793 | chr19_57715384_+ | intronic |
| ADediting_785794 | chr19_57715413_+ | intronic |
| ADediting_785795 | chr19_57716215_+ | intronic |
| ADediting_785796 | chr19_57716248_+ | intronic |
| ADediting_785797 | chr19_57716254_+ | intronic |
| ADediting_785798 | chr19_57716300_+ | intronic |
| ADediting_785799 | chr19_57716364_+ | intronic |
| ADediting_1559353 | chr19_57685286_+ | exonic |
| ADediting_1559354 | chr19_57685323_+ | exonic |
| ADediting_1559355 | chr19_57688914_+ | UTR3 |
| ADediting_1559356 | chr19_57689598_+ | UTR3 |
| ADediting_1559357 | chr19_57691500_+ | intronic |
| ADediting_1559358 | chr19_57691536_+ | intronic |
| ADediting_1559359 | chr19_57691552_+ | intronic |
| ADediting_1559360 | chr19_57692406_+ | intronic |
| ADediting_1559361 | chr19_57713219_+ | intronic |
| ADediting_1559362 | chr19_57714308_+ | intronic |
| ADediting_1559363 | chr19_57714310_+ | intronic |
| ADediting_1559364 | chr19_57715220_+ | intronic |
| ADediting_1631718 | chr19_57689634_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_785715 | chr19_57689597_+ | SINE | Alu | Name=AluSx3 |
| ADediting_785720 | chr19_57691182_+ | SINE | Alu | Name=AluSx4 |
| ADediting_785721 | chr19_57691251_+ | SINE | Alu | Name=AluSx4 |
| ADediting_785722 | chr19_57691351_+ | SINE | Alu | Name=AluSx4 |
| ADediting_785723 | chr19_57691481_+ | DNA | hAT-Tip100 | Name=MER63D |
| ADediting_785724 | chr19_57691503_+ | DNA | hAT-Tip100 | Name=MER63D |
| ADediting_785725 | chr19_57691513_+ | DNA | hAT-Tip100 | Name=MER63D |
| ADediting_785728 | chr19_57693235_+ | SINE | Alu | Name=AluSg |
| ADediting_785729 | chr19_57693243_+ | SINE | Alu | Name=AluSg |
| ADediting_785730 | chr19_57693376_+ | SINE | Alu | Name=AluSg |
| ADediting_785731 | chr19_57693412_+ | SINE | Alu | Name=AluSg |
| ADediting_785732 | chr19_57693418_+ | SINE | Alu | Name=AluSg |
| ADediting_785733 | chr19_57693436_+ | SINE | Alu | Name=AluSg |
| ADediting_785734 | chr19_57693439_+ | SINE | Alu | Name=AluSg |
| ADediting_785735 | chr19_57694975_+ | SINE | Alu | Name=AluSx |
| ADediting_785736 | chr19_57695014_+ | SINE | Alu | Name=AluSx |
| ADediting_785737 | chr19_57695067_+ | SINE | Alu | Name=AluSx |
| ADediting_785738 | chr19_57695077_+ | SINE | Alu | Name=AluSx |
| ADediting_785739 | chr19_57695082_+ | SINE | Alu | Name=AluSx |
| ADediting_785740 | chr19_57695088_+ | SINE | Alu | Name=AluSx |
| ADediting_785741 | chr19_57695091_+ | SINE | Alu | Name=AluSx |
| ADediting_785742 | chr19_57695106_+ | SINE | Alu | Name=AluSx |
| ADediting_785743 | chr19_57695132_+ | SINE | Alu | Name=AluSx |
| ADediting_785744 | chr19_57695133_+ | SINE | Alu | Name=AluSx |
| ADediting_785745 | chr19_57695142_+ | SINE | Alu | Name=AluSx |
| ADediting_785746 | chr19_57695355_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785747 | chr19_57695365_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785748 | chr19_57695391_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785749 | chr19_57695392_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785750 | chr19_57695406_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785751 | chr19_57695411_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785752 | chr19_57695415_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785753 | chr19_57695461_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785754 | chr19_57695487_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785755 | chr19_57695488_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785756 | chr19_57695500_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785757 | chr19_57695602_+ | SINE | Alu | Name=AluSp |
| ADediting_785758 | chr19_57695607_+ | SINE | Alu | Name=AluSp |
| ADediting_785760 | chr19_57709760_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785761 | chr19_57709813_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785762 | chr19_57709820_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785763 | chr19_57709824_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785764 | chr19_57709834_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785765 | chr19_57709860_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785766 | chr19_57709870_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785767 | chr19_57709896_+ | SINE | Alu | Name=AluSz6 |
| ADediting_785768 | chr19_57713685_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785769 | chr19_57713701_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785770 | chr19_57713711_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785771 | chr19_57713712_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785772 | chr19_57713769_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785773 | chr19_57713771_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785774 | chr19_57713779_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785775 | chr19_57713869_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785776 | chr19_57713886_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785777 | chr19_57713896_+ | SINE | Alu | Name=AluSx1 |
| ADediting_785778 | chr19_57714302_+ | SINE | Alu | Name=AluJo |
| ADediting_785779 | chr19_57714303_+ | SINE | Alu | Name=AluJo |
| ADediting_785780 | chr19_57714311_+ | SINE | Alu | Name=AluJo |
| ADediting_785781 | chr19_57714383_+ | SINE | Alu | Name=AluJo |
| ADediting_785782 | chr19_57714393_+ | SINE | Alu | Name=AluJo |
| ADediting_785783 | chr19_57714411_+ | SINE | Alu | Name=AluJo |
| ADediting_785784 | chr19_57714435_+ | SINE | Alu | Name=AluJo |
| ADediting_785785 | chr19_57714447_+ | SINE | Alu | Name=AluJo |
| ADediting_785786 | chr19_57715176_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785787 | chr19_57715206_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785788 | chr19_57715236_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785789 | chr19_57715237_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785790 | chr19_57715251_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785791 | chr19_57715252_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785792 | chr19_57715383_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785793 | chr19_57715384_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785794 | chr19_57715413_+ | SINE | Alu | Name=AluSg4 |
| ADediting_785795 | chr19_57716215_+ | SINE | Alu | Name=AluSp |
| ADediting_785796 | chr19_57716248_+ | SINE | Alu | Name=AluSp |
| ADediting_785797 | chr19_57716254_+ | SINE | Alu | Name=AluSp |
| ADediting_785798 | chr19_57716300_+ | SINE | Alu | Name=AluSp |
| ADediting_785799 | chr19_57716364_+ | SINE | Alu | Name=AluSp |
| ADediting_1559356 | chr19_57689598_+ | SINE | Alu | Name=AluSx3 |
| ADediting_1559357 | chr19_57691500_+ | DNA | hAT-Tip100 | Name=MER63D |
| ADediting_1559358 | chr19_57691536_+ | DNA | hAT-Tip100 | Name=MER63D |
| ADediting_1559359 | chr19_57691552_+ | DNA | hAT-Tip100 | Name=MER63D |
| ADediting_1559360 | chr19_57692406_+ | SINE | Alu | Name=AluYc |
| ADediting_1559361 | chr19_57713219_+ | LTR | ERVL-MaLR | Name=MSTB |
| ADediting_1559362 | chr19_57714308_+ | SINE | Alu | Name=AluJo |
| ADediting_1559363 | chr19_57714310_+ | SINE | Alu | Name=AluJo |
| ADediting_1559364 | chr19_57715220_+ | SINE | Alu | Name=AluSg4 |
| ADediting_1631718 | chr19_57689634_+ | SINE | Alu | Name=AluSx3 |
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RNA A-to-I editing events in the alternative splicing sites for ZNF551 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF551 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ZNF551 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ZNF551 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559355 | chr19_57688914_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-5001-3p | chr19 | 57688912 | 57688919 | 8mer-1a | 57688902 | 57688919 | 142 | -18.88 |
| ADediting_1559356 | chr19_57689598_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-12113 | chr19 | 57689591 | 57689597 | 7mer-m8 | 57689578 | 57689598 | 149 | -21.1 |
| ADediting_1559356 | chr19_57689598_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-4539 | chr19 | 57689591 | 57689597 | 7mer-m8 | 57689579 | 57689598 | 159 | -24.23 |
| ADediting_1631718 | chr19_57689634_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-3166 | chr19 | 57689628 | 57689634 | 7mer-m8 | 57689614 | 57689635 | 141 | -14.13 |
| ADediting_1631718 | chr19_57689634_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-374b-3p | chr19 | 57689631 | 57689638 | 8mer-1a | 57689616 | 57689638 | 153 | -12.55 |
| ADediting_785714 | chr19_57689513_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-10523-5p | chr19 | 57689507 | 57689513 | 7mer-m8 | 57689491 | 57689514 | 145 | -14.78 |
| ADediting_785716 | chr19_57689881_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-3120-3p | chr19 | 57689875 | 57689881 | 7mer-m8 | 57689862 | 57689882 | 143 | -18.51 |
| ADediting_785718 | chr19_57689966_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-6826-5p | chr19 | 57689959 | 57689966 | 8mer-1a | 57689942 | 57689966 | 159 | -20.44 |
| ADediting_785719 | chr19_57690020_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-6732-3p | chr19 | 57690017 | 57690023 | 7mer-m8 | 57690003 | 57690024 | 151 | -23.15 |
| ADediting_785719 | chr19_57690020_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-6747-3p | chr19 | 57690014 | 57690020 | 7mer-m8 | 57690001 | 57690021 | 141 | -19.22 |
| ADediting_785719 | chr19_57690020_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-6752-3p | chr19 | 57690015 | 57690021 | 7mer-m8 | 57690002 | 57690022 | 142 | -18.04 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1631718 | chr19_57689634_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-411-5p | chr19 | 57689629 | 57689636 | 8mer-1a | 57689616 | 57689636 | 140 | -13.29 |
| ADediting_785716 | chr19_57689881_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-153-3p | chr19 | 57689878 | 57689884 | 7mer-m8 | 57689864 | 57689885 | 143 | -13.73 |
| ADediting_785718 | chr19_57689966_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-183-3p | chr19 | 57689964 | 57689970 | 7mer-m8 | 57689952 | 57689971 | 141 | -8.35 |
| ADediting_785719 | chr19_57690020_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-1915-5p | chr19 | 57690015 | 57690021 | 7mer-m8 | 57690001 | 57690022 | 150 | -21.43 |
| ADediting_785719 | chr19_57690020_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-3152-5p | chr19 | 57690013 | 57690019 | 7mer-m8 | 57689999 | 57690020 | 148 | -12.52 |
| ADediting_785719 | chr19_57690020_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-3200-3p | chr19 | 57690016 | 57690022 | 7mer-m8 | 57690006 | 57690023 | 149 | -19.22 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_785713 | chr19_57686575_+ | ENSG00000204519.11 | ENST00000599402.1 | ZNF551-203 | hsa-miR-627-5p | chr19 | 57686574 | 57686580 | 7mer-m8 | 57686559 | 57686581 | 141 | -14.96 |
| ADediting_785713 | chr19_57686575_+ | ENSG00000204519.11 | ENST00000599402.1 | ZNF551-203 | hsa-miR-6740-3p | chr19 | 57686571 | 57686577 | 7mer-m8 | 57686557 | 57686578 | 140 | -8.45 |
| ADediting_785713 | chr19_57686575_+ | ENSG00000204519.11 | ENST00000599402.1 | ZNF551-203 | hsa-miR-924 | chr19 | 57686573 | 57686580 | 8mer-1a | 57686561 | 57686580 | 147 | -12.86 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-381-3p | chr19 | 57689081 | 57689087 | 7mer-m8 | 57689065 | 57689088 | 153 | -21.1 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-381-3p | chr19 | 57689840 | 57689846 | 7mer-m8 | 57689822 | 57689847 | 151 | -15.78 |
| ADediting_1535953 | chr14_101045971_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-381-3p | chr19 | 57690266 | 57690272 | 7mer-m8 | 57690252 | 57690273 | 150 | -10.64 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-381-3p | chr19 | 57689840 | 57689846 | 7mer-m8 | 57689822 | 57689847 | 151 | -15.78 |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-381-3p | chr19 | 57690266 | 57690272 | 7mer-m8 | 57690252 | 57690273 | 150 | -10.64 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-641 | chr19 | 57688643 | 57688649 | 7mer-m8 | 57688626 | 57688650 | 148 | -14.4 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-641 | chr19 | 57688643 | 57688649 | 7mer-m8 | 57688626 | 57688650 | 148 | -14.4 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-5585-3p | chr19 | 57688887 | 57688893 | 7mer-m8 | 57688868 | 57688894 | 147 | -14.87 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000204519.11 | ENST00000282296.10 | ZNF551-201 | hsa-miR-5585-3p | chr19 | 57688887 | 57688893 | 7mer-m8 | 57688868 | 57688894 | 147 | -14.87 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ZNF551 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000601064.1 | protein_coding |  |  |
| ENST00000599402.1 | lncRNA |  |  |
| ENST00000282296.10 | protein_coding |  |  |
| ENST00000596085.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1559353 | ENST00000601064.1 | chr19_57685286_+ | 179 | -549.60 | -550.00 | -553.50 |
| ADediting_785708 | ENST00000601064.1 | chr19_57685299_+ | 192 | -550.00 | -550.00 | -553.50 |
| ADediting_785709 | ENST00000601064.1 | chr19_57685300_+ | 193 | -550.80 | -550.00 | -553.50 |
| ADediting_785710 | ENST00000601064.1 | chr19_57685303_+ | 196 | -551.00 | -550.00 | -553.50 |
| ADediting_1559354 | ENST00000601064.1 | chr19_57685323_+ | 216 | -553.10 | -550.00 | -553.50 |
| ADediting_785711 | ENST00000601064.1 | chr19_57685329_+ | 222 | -549.20 | -550.00 | -553.50 |
| ADediting_785712 | ENST00000601064.1 | chr19_57685341_+ | 234 | -550.00 | -550.00 | -553.50 |
| ADediting_785713 | ENST00000601064.1 | chr19_57686575_+ | 373 | -550.20 | -550.00 | -553.50 |
| ADediting_1559353 | ENST00000282296.10 | chr19_57685286_+ | 293 | -1411.00 | -1413.50 | -1426.30 |
| ADediting_785708 | ENST00000282296.10 | chr19_57685299_+ | 306 | -1415.50 | -1413.50 | -1426.30 |
| ADediting_785709 | ENST00000282296.10 | chr19_57685300_+ | 307 | -1414.00 | -1413.50 | -1426.30 |
| ADediting_785710 | ENST00000282296.10 | chr19_57685303_+ | 310 | -1414.40 | -1413.50 | -1426.30 |
| ADediting_1559354 | ENST00000282296.10 | chr19_57685323_+ | 330 | -1417.00 | -1413.50 | -1426.30 |
| ADediting_785711 | ENST00000282296.10 | chr19_57685329_+ | 336 | -1413.50 | -1413.50 | -1426.30 |
| ADediting_785712 | ENST00000282296.10 | chr19_57685341_+ | 348 | -1411.90 | -1413.50 | -1426.30 |
| ADediting_785713 | ENST00000282296.10 | chr19_57686575_+ | 487 | -1416.10 | -1413.50 | -1426.30 |
| ADediting_1559355 | ENST00000282296.10 | chr19_57688914_+ | 2826 | -1413.50 | -1413.50 | -1426.30 |
| ADediting_785714 | ENST00000282296.10 | chr19_57689513_+ | 3425 | -1414.10 | -1413.50 | -1426.30 |
| ADediting_785715 | ENST00000282296.10 | chr19_57689597_+ | 3509 | -1412.80 | -1413.50 | -1426.30 |
| ADediting_1559356 | ENST00000282296.10 | chr19_57689598_+ | 3510 | -1416.60 | -1413.50 | -1426.30 |
| ADediting_1631718 | ENST00000282296.10 | chr19_57689634_+ | 3546 | -1416.90 | -1413.50 | -1426.30 |
| ADediting_785716 | ENST00000282296.10 | chr19_57689881_+ | 3793 | -1413.50 | -1413.50 | -1426.30 |
| ADediting_785717 | ENST00000282296.10 | chr19_57689963_+ | 3875 | -1413.50 | -1413.50 | -1426.30 |
| ADediting_785718 | ENST00000282296.10 | chr19_57689966_+ | 3878 | -1413.60 | -1413.50 | -1426.30 |
| ADediting_785719 | ENST00000282296.10 | chr19_57690020_+ | 3932 | -1415.30 | -1413.50 | -1426.30 |
| ADediting_1559353 | ENST00000596085.1 | chr19_57685286_+ | 235 | -175.10 | -175.50 | -178.80 |
| ADediting_785708 | ENST00000596085.1 | chr19_57685299_+ | 248 | -175.50 | -175.50 | -178.80 |
| ADediting_785709 | ENST00000596085.1 | chr19_57685300_+ | 249 | -176.30 | -175.50 | -178.80 |
| ADediting_785710 | ENST00000596085.1 | chr19_57685303_+ | 252 | -176.50 | -175.50 | -178.80 |
| ADediting_1559354 | ENST00000596085.1 | chr19_57685323_+ | 272 | -178.60 | -175.50 | -178.80 |
| ADediting_785711 | ENST00000596085.1 | chr19_57685329_+ | 278 | -174.70 | -175.50 | -178.80 |
| ADediting_785712 | ENST00000596085.1 | chr19_57685341_+ | 290 | -175.50 | -175.50 | -178.80 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_785713 | ENST00000599402.1 | chr19_57686575_+ | 333 | -220.20 | -220.00 | -220.20 |
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Relation with ADAR for ZNF551 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 3.67927203443968e-19 | 0.478699234363123 | 6.63328119302596e-12 | 0.376969052809214 | 3.756341865294e-28 | 0.570408708977718 |
| AC | 1.1419588918922e-54 | 0.790250721282965 | 5.65173180662326e-35 | 0.677758149761115 | 4.58746875638464e-08 | 0.337246669349657 |
| PCC | 5.92778605891824e-22 | 0.623374776523381 | 3.69476715723853e-16 | 0.544840718051086 | 3.062937471342e-09 | 0.412410550030055 |
| CER | 9.97835140969328e-24 | 0.70367737084171 | 5.64451650017818e-14 | 0.564049851503938 | 0.305521744033274 | 0.0842192574593407 |
| TCX | 4.48409046251044e-10 | 0.481403157323084 | 6.13301365105963e-14 | 0.563380456280192 | 0.0730419061735213 | 0.146796689880299 |
| FP | 2.36957828423381e-22 | 0.645395457251989 | 2.12522066901771e-19 | 0.608342958858987 | 1.78432995678599e-07 | 0.379248221662914 |
| IFG | 2.06953829571846e-05 | 0.743320157103984 | 5.49830382869938e-05 | 0.717053762080309 | 0.01902271916804 | 0.465517968942573 |
| PG | 4.98575106890555e-33 | 0.736221089203455 | 1.24583236217217e-24 | 0.659967762598528 | 0.523776548934613 | 0.0470375294233868 |
| STG | 3.40493992220995e-14 | 0.711286962003269 | 2.02567525833633e-08 | 0.565917674835165 | 0.0011382652374373 | 0.349025775682581 |
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Relation with AD stages for ZNF551 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 5.97766987042583e-05 | 0.379645746554132 |
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RelatedDrugs for ZNF551 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZNF551 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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