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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for ZSWIM1

check button Gene summary
Gene informationGene symbol

ZSWIM1

Gene ID

90204

Gene namezinc finger SWIM-type containing 1
SynonymsC20orf162
Cytomap

20q13.12

Type of geneprotein-coding
Descriptionzinc finger SWIM domain-containing protein 1zinc finger, SWIM domain containing 1
Modification date20200313
UniProtAcc

Q9BR11,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ZSWIM1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_938352(45884385, +), ADediting_938353(45884388, +), ADediting_938354(45884427, +), ADediting_938355(45884437, +), ADediting_938356(45884443, +), ADediting_938357(45884449, +), ADediting_938358(45884464, +), ADediting_938359(45884480, +), ADediting_938360(45884492, +), ADediting_938361(45884502, +), ADediting_938362(45884528, +), ADediting_938363(45884529, +), ADediting_938364(45884544, +), ADediting_938365(45884547, +), ADediting_938366(45884569, +), ADediting_938367(45884622, +), ADediting_938368(45884623, +), ADediting_938369(45884624, +), ADediting_938370(45884636, +), ADediting_938371(45884747, +), ADediting_938372(45884755, +), ADediting_938373(45884756, +), ADediting_938374(45884761, +), ADediting_938375(45884801, +), ADediting_938376(45884809, +), ADediting_938377(45884810, +), ADediting_938378(45884815, +), ADediting_938379(45884824, +), ADediting_938380(45884825, +), ADediting_938381(45884829, +), ADediting_938382(45884833, +), ADediting_938383(45884835, +), ADediting_938384(45884849, +), ADediting_938385(45884850, +), ADediting_938386(45884851, +), ADediting_938387(45884852, +), ADediting_938388(45884855, +), ADediting_938389(45884861, +), ADediting_938390(45884864, +), ADediting_938391(45884891, +), ADediting_938392(45884892, +), ADediting_938393(45884897, +), ADediting_938394(45884901, +), ADediting_938395(45884918, +), ADediting_938396(45884924, +), ADediting_938397(45884933, +), ADediting_938398(45884944, +), ADediting_938399(45884956, +), ADediting_938400(45884961, +), ADediting_938401(45884962, +), ADediting_938402(45884999, +),

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RNA editing positional annotations for ZSWIM1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_938352chr20_45884385_+UTR3
ADediting_938353chr20_45884388_+UTR3
ADediting_938354chr20_45884427_+UTR3
ADediting_938355chr20_45884437_+UTR3
ADediting_938356chr20_45884443_+UTR3
ADediting_938357chr20_45884449_+UTR3
ADediting_938358chr20_45884464_+UTR3
ADediting_938359chr20_45884480_+UTR3
ADediting_938360chr20_45884492_+UTR3
ADediting_938361chr20_45884502_+UTR3
ADediting_938362chr20_45884528_+UTR3
ADediting_938363chr20_45884529_+UTR3
ADediting_938364chr20_45884544_+UTR3
ADediting_938365chr20_45884547_+UTR3
ADediting_938366chr20_45884569_+UTR3
ADediting_938367chr20_45884622_+UTR3
ADediting_938368chr20_45884623_+UTR3
ADediting_938369chr20_45884624_+UTR3
ADediting_938370chr20_45884636_+UTR3
ADediting_938371chr20_45884747_+UTR3
ADediting_938372chr20_45884755_+UTR3
ADediting_938373chr20_45884756_+UTR3
ADediting_938374chr20_45884761_+UTR3
ADediting_938375chr20_45884801_+UTR3
ADediting_938376chr20_45884809_+UTR3
ADediting_938377chr20_45884810_+UTR3
ADediting_938378chr20_45884815_+UTR3
ADediting_938379chr20_45884824_+UTR3
ADediting_938380chr20_45884825_+UTR3
ADediting_938381chr20_45884829_+UTR3
ADediting_938382chr20_45884833_+UTR3
ADediting_938383chr20_45884835_+UTR3
ADediting_938384chr20_45884849_+UTR3
ADediting_938385chr20_45884850_+UTR3
ADediting_938386chr20_45884851_+UTR3
ADediting_938387chr20_45884852_+UTR3
ADediting_938388chr20_45884855_+UTR3
ADediting_938389chr20_45884861_+UTR3
ADediting_938390chr20_45884864_+UTR3
ADediting_938391chr20_45884891_+UTR3
ADediting_938392chr20_45884892_+UTR3
ADediting_938393chr20_45884897_+UTR3
ADediting_938394chr20_45884901_+UTR3
ADediting_938395chr20_45884918_+UTR3
ADediting_938396chr20_45884924_+UTR3
ADediting_938397chr20_45884933_+UTR3
ADediting_938398chr20_45884944_+UTR3
ADediting_938399chr20_45884956_+UTR3
ADediting_938400chr20_45884961_+UTR3
ADediting_938401chr20_45884962_+UTR3
ADediting_938402chr20_45884999_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_938352chr20_45884385_+SINEAluName=AluY
ADediting_938353chr20_45884388_+SINEAluName=AluY
ADediting_938354chr20_45884427_+SINEAluName=AluY
ADediting_938355chr20_45884437_+SINEAluName=AluY
ADediting_938356chr20_45884443_+SINEAluName=AluY
ADediting_938357chr20_45884449_+SINEAluName=AluY
ADediting_938358chr20_45884464_+SINEAluName=AluY
ADediting_938359chr20_45884480_+SINEAluName=AluY
ADediting_938360chr20_45884492_+SINEAluName=AluY
ADediting_938361chr20_45884502_+SINEAluName=AluY
ADediting_938362chr20_45884528_+SINEAluName=AluY
ADediting_938363chr20_45884529_+SINEAluName=AluY
ADediting_938364chr20_45884544_+SINEAluName=AluY
ADediting_938365chr20_45884547_+SINEAluName=AluY
ADediting_938366chr20_45884569_+SINEAluName=AluY
ADediting_938367chr20_45884622_+SINEAluName=AluY
ADediting_938368chr20_45884623_+SINEAluName=AluY
ADediting_938369chr20_45884624_+SINEAluName=AluY
ADediting_938370chr20_45884636_+SINEAluName=AluY
ADediting_938371chr20_45884747_+SINEAluName=AluSx1
ADediting_938372chr20_45884755_+SINEAluName=AluSx1
ADediting_938373chr20_45884756_+SINEAluName=AluSx1
ADediting_938374chr20_45884761_+SINEAluName=AluSx1
ADediting_938375chr20_45884801_+SINEAluName=AluSx1
ADediting_938376chr20_45884809_+SINEAluName=AluSx1
ADediting_938377chr20_45884810_+SINEAluName=AluSx1
ADediting_938378chr20_45884815_+SINEAluName=AluSx1
ADediting_938379chr20_45884824_+SINEAluName=AluSx1
ADediting_938380chr20_45884825_+SINEAluName=AluSx1
ADediting_938381chr20_45884829_+SINEAluName=AluSx1
ADediting_938382chr20_45884833_+SINEAluName=AluSx1
ADediting_938383chr20_45884835_+SINEAluName=AluSx1
ADediting_938384chr20_45884849_+SINEAluName=AluSx1
ADediting_938385chr20_45884850_+SINEAluName=AluSx1
ADediting_938386chr20_45884851_+SINEAluName=AluSx1
ADediting_938387chr20_45884852_+SINEAluName=AluSx1
ADediting_938388chr20_45884855_+SINEAluName=AluSx1
ADediting_938389chr20_45884861_+SINEAluName=AluSx1
ADediting_938390chr20_45884864_+SINEAluName=AluSx1
ADediting_938391chr20_45884891_+SINEAluName=AluSx1
ADediting_938392chr20_45884892_+SINEAluName=AluSx1
ADediting_938393chr20_45884897_+SINEAluName=AluSx1
ADediting_938394chr20_45884901_+SINEAluName=AluSx1
ADediting_938395chr20_45884918_+SINEAluName=AluSx1
ADediting_938396chr20_45884924_+SINEAluName=AluSx1
ADediting_938397chr20_45884933_+SINEAluName=AluSx1
ADediting_938398chr20_45884944_+SINEAluName=AluSx1
ADediting_938399chr20_45884956_+SINEAluName=AluSx1
ADediting_938400chr20_45884961_+SINEAluName=AluSx1
ADediting_938401chr20_45884962_+SINEAluName=AluSx1
ADediting_938402chr20_45884999_+SINEAluName=AluSx1

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RNA A-to-I editing events in the alternative splicing sites for ZSWIM1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZSWIM1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs