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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PAPLN |
 Gene summary |
| Gene information | Gene symbol | PAPLN | Gene ID | 89932 |
| Gene name | papilin, proteoglycan like sulfated glycoprotein | |
| Synonyms | PPN | |
| Cytomap | 14q24.2 | |
| Type of gene | protein-coding | |
| Description | papilin | |
| Modification date | 20200313 | |
| UniProtAcc | O95428, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for PAPLN |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_447856(73246331, +), ADediting_447857(73246662, +), ADediting_447858(73246724, +), ADediting_447859(73246725, +), ADediting_447860(73248679, +), ADediting_447861(73248719, +), ADediting_447862(73248747, +), ADediting_447863(73248853, +), ADediting_447864(73249412, +), ADediting_447865(73249593, +), ADediting_447866(73255477, +), ADediting_447867(73256284, +), ADediting_447868(73256311, +), ADediting_447869(73256316, +), ADediting_447870(73256317, +), ADediting_447871(73256366, +), ADediting_447872(73256369, +), ADediting_447873(73256371, +), ADediting_447874(73256375, +), ADediting_447875(73256385, +), ADediting_447876(73256411, +), ADediting_447877(73256452, +), ADediting_447878(73256453, +), ADediting_447879(73256487, +), ADediting_447880(73256497, +), ADediting_447881(73256508, +), ADediting_447882(73256631, +), ADediting_447883(73256672, +), ADediting_447884(73256706, +), ADediting_447885(73256721, +), ADediting_447886(73256723, +), ADediting_447887(73256724, +), ADediting_447888(73256736, +), ADediting_447889(73256762, +), ADediting_447890(73256763, +), ADediting_447891(73256789, +), ADediting_447892(73256794, +), ADediting_447893(73256803, +), ADediting_447894(73256804, +), ADediting_447895(73256840, +), ADediting_447896(73256970, +), ADediting_447897(73256999, +), ADediting_447898(73257033, +), ADediting_447899(73257051, +), ADediting_447900(73257072, +), ADediting_447901(73257084, +), ADediting_447902(73257101, +), ADediting_447903(73257106, +), ADediting_447904(73257111, +), ADediting_447905(73257113, +), ADediting_447906(73257137, +), ADediting_447907(73257138, +), ADediting_447908(73257181, +), ADediting_447909(73257206, +), ADediting_447910(73257210, +), ADediting_447911(73257211, +), ADediting_447912(73257234, +), ADediting_447913(73257828, +), ADediting_447914(73257843, +), ADediting_447915(73257844, +), ADediting_447916(73257857, +), ADediting_447917(73257863, +), ADediting_447918(73257864, +), ADediting_447919(73257893, +), ADediting_447920(73257903, +), ADediting_447921(73257938, +), ADediting_447922(73257944, +), ADediting_447923(73257947, +), ADediting_447924(73257961, +), ADediting_447925(73258000, +), ADediting_447926(73258506, +), ADediting_447927(73258574, +), ADediting_447928(73258602, +), ADediting_447929(73258665, +), ADediting_447930(73258674, +), ADediting_447931(73258677, +), ADediting_447932(73258687, +), ADediting_447933(73258717, +), ADediting_447934(73266061, +), ADediting_447935(73266137, +), ADediting_447936(73266183, +), |
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RNA editing positional annotations for PAPLN using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_447856 | chr14_73246331_+ | intronic |
| ADediting_447857 | chr14_73246662_+ | intronic |
| ADediting_447858 | chr14_73246724_+ | intronic |
| ADediting_447859 | chr14_73246725_+ | intronic |
| ADediting_447860 | chr14_73248679_+ | intronic |
| ADediting_447861 | chr14_73248719_+ | intronic |
| ADediting_447862 | chr14_73248747_+ | intronic |
| ADediting_447863 | chr14_73248853_+ | intronic |
| ADediting_447864 | chr14_73249412_+ | intronic |
| ADediting_447865 | chr14_73249593_+ | intronic |
| ADediting_447866 | chr14_73255477_+ | intronic |
| ADediting_447867 | chr14_73256284_+ | intronic |
| ADediting_447868 | chr14_73256311_+ | intronic |
| ADediting_447869 | chr14_73256316_+ | intronic |
| ADediting_447870 | chr14_73256317_+ | intronic |
| ADediting_447871 | chr14_73256366_+ | intronic |
| ADediting_447872 | chr14_73256369_+ | intronic |
| ADediting_447873 | chr14_73256371_+ | intronic |
| ADediting_447874 | chr14_73256375_+ | intronic |
| ADediting_447875 | chr14_73256385_+ | intronic |
| ADediting_447876 | chr14_73256411_+ | intronic |
| ADediting_447877 | chr14_73256452_+ | intronic |
| ADediting_447878 | chr14_73256453_+ | intronic |
| ADediting_447879 | chr14_73256487_+ | intronic |
| ADediting_447880 | chr14_73256497_+ | intronic |
| ADediting_447881 | chr14_73256508_+ | intronic |
| ADediting_447882 | chr14_73256631_+ | intronic |
| ADediting_447883 | chr14_73256672_+ | intronic |
| ADediting_447884 | chr14_73256706_+ | intronic |
| ADediting_447885 | chr14_73256721_+ | intronic |
| ADediting_447886 | chr14_73256723_+ | intronic |
| ADediting_447887 | chr14_73256724_+ | intronic |
| ADediting_447888 | chr14_73256736_+ | intronic |
| ADediting_447889 | chr14_73256762_+ | intronic |
| ADediting_447890 | chr14_73256763_+ | intronic |
| ADediting_447891 | chr14_73256789_+ | intronic |
| ADediting_447892 | chr14_73256794_+ | intronic |
| ADediting_447893 | chr14_73256803_+ | intronic |
| ADediting_447894 | chr14_73256804_+ | intronic |
| ADediting_447895 | chr14_73256840_+ | intronic |
| ADediting_447896 | chr14_73256970_+ | intronic |
| ADediting_447897 | chr14_73256999_+ | intronic |
| ADediting_447898 | chr14_73257033_+ | intronic |
| ADediting_447899 | chr14_73257051_+ | intronic |
| ADediting_447900 | chr14_73257072_+ | intronic |
| ADediting_447901 | chr14_73257084_+ | intronic |
| ADediting_447902 | chr14_73257101_+ | intronic |
| ADediting_447903 | chr14_73257106_+ | intronic |
| ADediting_447904 | chr14_73257111_+ | intronic |
| ADediting_447905 | chr14_73257113_+ | intronic |
| ADediting_447906 | chr14_73257137_+ | intronic |
| ADediting_447907 | chr14_73257138_+ | intronic |
| ADediting_447908 | chr14_73257181_+ | intronic |
| ADediting_447909 | chr14_73257206_+ | intronic |
| ADediting_447910 | chr14_73257210_+ | intronic |
| ADediting_447911 | chr14_73257211_+ | intronic |
| ADediting_447912 | chr14_73257234_+ | intronic |
| ADediting_447913 | chr14_73257828_+ | intronic |
| ADediting_447914 | chr14_73257843_+ | intronic |
| ADediting_447915 | chr14_73257844_+ | intronic |
| ADediting_447916 | chr14_73257857_+ | intronic |
| ADediting_447917 | chr14_73257863_+ | intronic |
| ADediting_447918 | chr14_73257864_+ | intronic |
| ADediting_447919 | chr14_73257893_+ | intronic |
| ADediting_447920 | chr14_73257903_+ | intronic |
| ADediting_447921 | chr14_73257938_+ | intronic |
| ADediting_447922 | chr14_73257944_+ | intronic |
| ADediting_447923 | chr14_73257947_+ | intronic |
| ADediting_447924 | chr14_73257961_+ | intronic |
| ADediting_447925 | chr14_73258000_+ | intronic |
| ADediting_447926 | chr14_73258506_+ | intronic |
| ADediting_447927 | chr14_73258574_+ | intronic |
| ADediting_447928 | chr14_73258602_+ | intronic |
| ADediting_447929 | chr14_73258665_+ | intronic |
| ADediting_447930 | chr14_73258674_+ | intronic |
| ADediting_447931 | chr14_73258677_+ | intronic |
| ADediting_447932 | chr14_73258687_+ | intronic |
| ADediting_447933 | chr14_73258717_+ | intronic |
| ADediting_447934 | chr14_73266061_+ | intronic |
| ADediting_447935 | chr14_73266137_+ | intronic |
| ADediting_447936 | chr14_73266183_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_447856 | chr14_73246331_+ | SINE | Alu | Name=FLAM_C |
| ADediting_447857 | chr14_73246662_+ | SINE | Alu | Name=AluJb |
| ADediting_447858 | chr14_73246724_+ | SINE | Alu | Name=AluJb |
| ADediting_447859 | chr14_73246725_+ | SINE | Alu | Name=AluJb |
| ADediting_447860 | chr14_73248679_+ | SINE | Alu | Name=AluJb |
| ADediting_447861 | chr14_73248719_+ | SINE | Alu | Name=AluJb |
| ADediting_447862 | chr14_73248747_+ | SINE | Alu | Name=AluJb |
| ADediting_447863 | chr14_73248853_+ | SINE | Alu | Name=AluJb |
| ADediting_447864 | chr14_73249412_+ | SINE | Alu | Name=AluSq |
| ADediting_447865 | chr14_73249593_+ | SINE | Alu | Name=AluSq |
| ADediting_447867 | chr14_73256284_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447868 | chr14_73256311_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447869 | chr14_73256316_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447870 | chr14_73256317_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447871 | chr14_73256366_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447872 | chr14_73256369_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447873 | chr14_73256371_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447874 | chr14_73256375_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447875 | chr14_73256385_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447876 | chr14_73256411_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447877 | chr14_73256452_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447878 | chr14_73256453_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447879 | chr14_73256487_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447880 | chr14_73256497_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447881 | chr14_73256508_+ | SINE | Alu | Name=AluSq2 |
| ADediting_447882 | chr14_73256631_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447883 | chr14_73256672_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447884 | chr14_73256706_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447885 | chr14_73256721_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447886 | chr14_73256723_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447887 | chr14_73256724_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447888 | chr14_73256736_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447889 | chr14_73256762_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447890 | chr14_73256763_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447891 | chr14_73256789_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447892 | chr14_73256794_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447893 | chr14_73256803_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447894 | chr14_73256804_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447895 | chr14_73256840_+ | SINE | Alu | Name=AluSz6 |
| ADediting_447897 | chr14_73256999_+ | SINE | Alu | Name=AluJo |
| ADediting_447898 | chr14_73257033_+ | SINE | Alu | Name=AluJo |
| ADediting_447899 | chr14_73257051_+ | SINE | Alu | Name=AluJo |
| ADediting_447900 | chr14_73257072_+ | SINE | Alu | Name=AluJo |
| ADediting_447901 | chr14_73257084_+ | SINE | Alu | Name=AluJo |
| ADediting_447902 | chr14_73257101_+ | SINE | Alu | Name=AluJo |
| ADediting_447903 | chr14_73257106_+ | SINE | Alu | Name=AluJo |
| ADediting_447904 | chr14_73257111_+ | SINE | Alu | Name=AluJo |
| ADediting_447905 | chr14_73257113_+ | SINE | Alu | Name=AluJo |
| ADediting_447906 | chr14_73257137_+ | SINE | Alu | Name=AluJo |
| ADediting_447907 | chr14_73257138_+ | SINE | Alu | Name=AluJo |
| ADediting_447908 | chr14_73257181_+ | SINE | Alu | Name=AluJo |
| ADediting_447909 | chr14_73257206_+ | SINE | Alu | Name=AluJo |
| ADediting_447910 | chr14_73257210_+ | SINE | Alu | Name=AluJo |
| ADediting_447911 | chr14_73257211_+ | SINE | Alu | Name=AluJo |
| ADediting_447912 | chr14_73257234_+ | SINE | Alu | Name=AluJo |
| ADediting_447913 | chr14_73257828_+ | SINE | Alu | Name=AluSz |
| ADediting_447914 | chr14_73257843_+ | SINE | Alu | Name=AluSz |
| ADediting_447915 | chr14_73257844_+ | SINE | Alu | Name=AluSz |
| ADediting_447916 | chr14_73257857_+ | SINE | Alu | Name=AluSz |
| ADediting_447917 | chr14_73257863_+ | SINE | Alu | Name=AluSz |
| ADediting_447918 | chr14_73257864_+ | SINE | Alu | Name=AluSz |
| ADediting_447919 | chr14_73257893_+ | SINE | Alu | Name=AluSz |
| ADediting_447920 | chr14_73257903_+ | SINE | Alu | Name=AluSz |
| ADediting_447921 | chr14_73257938_+ | SINE | Alu | Name=AluSz |
| ADediting_447922 | chr14_73257944_+ | SINE | Alu | Name=AluSz |
| ADediting_447923 | chr14_73257947_+ | SINE | Alu | Name=AluSz |
| ADediting_447924 | chr14_73257961_+ | SINE | Alu | Name=AluSz |
| ADediting_447925 | chr14_73258000_+ | SINE | Alu | Name=AluSz |
| ADediting_447926 | chr14_73258506_+ | SINE | Alu | Name=AluJo |
| ADediting_447927 | chr14_73258574_+ | SINE | Alu | Name=AluJo |
| ADediting_447928 | chr14_73258602_+ | SINE | Alu | Name=AluJo |
| ADediting_447929 | chr14_73258665_+ | SINE | Alu | Name=AluJo |
| ADediting_447930 | chr14_73258674_+ | SINE | Alu | Name=AluJo |
| ADediting_447931 | chr14_73258677_+ | SINE | Alu | Name=AluJo |
| ADediting_447932 | chr14_73258687_+ | SINE | Alu | Name=AluJo |
| ADediting_447933 | chr14_73258717_+ | SINE | Alu | Name=AluJo |
| ADediting_447934 | chr14_73266061_+ | SINE | Alu | Name=AluSg7 |
| ADediting_447935 | chr14_73266137_+ | SINE | Alu | Name=AluSg7 |
| ADediting_447936 | chr14_73266183_+ | SINE | Alu | Name=AluSg7 |
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RNA A-to-I editing events in the alternative splicing sites for PAPLN |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PAPLN |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for PAPLN |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for PAPLN |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-589-3p | chr14 | 73274029 | 73274035 | 7mer-m8 | 73274015 | 73274036 | 147 | -19.17 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-589-3p | chr14 | 73274029 | 73274035 | 7mer-m8 | 73274015 | 73274036 | 147 | -19.17 |
| ADediting_1337757 | chr7_5495852_- | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-589-3p | chr14 | 73274029 | 73274035 | 7mer-m8 | 73274015 | 73274036 | 147 | -19.17 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-151a-3p | chr14 | 73272686 | 73272693 | 8mer-1a | 73272673 | 73272693 | 149 | -14.91 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000100767.16 | ENST00000554301.5 | PAPLN-203 | hsa-miR-151a-3p | chr14 | 73272686 | 73272693 | 8mer-1a | 73272673 | 73272693 | 149 | -14.91 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000100767.16 | ENST00000555445.5 | PAPLN-208 | hsa-miR-151a-3p | chr14 | 73272686 | 73272693 | 8mer-1a | 73272673 | 73272693 | 149 | -14.91 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-151a-3p | chr14 | 73272686 | 73272693 | 8mer-1a | 73272673 | 73272693 | 149 | -14.91 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-151a-3p | chr14 | 73272686 | 73272693 | 8mer-1a | 73272673 | 73272693 | 149 | -14.91 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-4775 | chr14 | 73273733 | 73273739 | 7mer-m8 | 73273719 | 73273740 | 140 | -11.24 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-4775 | chr14 | 73273733 | 73273739 | 7mer-m8 | 73273719 | 73273740 | 140 | -11.24 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-4775 | chr14 | 73273733 | 73273739 | 7mer-m8 | 73273719 | 73273740 | 140 | -11.24 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-5585-3p | chr14 | 73274483 | 73274489 | 7mer-m8 | 73274469 | 73274490 | 156 | -16.64 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-5585-3p | chr14 | 73274483 | 73274489 | 7mer-m8 | 73274469 | 73274490 | 156 | -16.64 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-5585-3p | chr14 | 73274483 | 73274489 | 7mer-m8 | 73274469 | 73274490 | 156 | -16.64 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-5688 | chr14 | 73272983 | 73272989 | 7mer-m8 | 73272969 | 73272990 | 155 | -11.72 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000100767.16 | ENST00000555445.5 | PAPLN-208 | hsa-miR-5688 | chr14 | 73272983 | 73272989 | 7mer-m8 | 73272969 | 73272990 | 155 | -11.72 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-5688 | chr14 | 73272983 | 73272989 | 7mer-m8 | 73272969 | 73272990 | 155 | -11.72 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-5688 | chr14 | 73272983 | 73272989 | 7mer-m8 | 73272969 | 73272990 | 155 | -11.72 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-4477b | chr14 | 73274063 | 73274069 | 7mer-m8 | 73274049 | 73274070 | 140 | -9.03 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-4477b | chr14 | 73274063 | 73274069 | 7mer-m8 | 73274049 | 73274070 | 140 | -9.03 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-4477b | chr14 | 73274063 | 73274069 | 7mer-m8 | 73274049 | 73274070 | 140 | -9.03 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000100767.16 | ENST00000340738.9 | PAPLN-202 | hsa-miR-4477b | chr14 | 73274063 | 73274069 | 7mer-m8 | 73274049 | 73274070 | 140 | -9.03 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000100767.16 | ENST00000559759.1 | PAPLN-211 | hsa-miR-4477b | chr14 | 73274063 | 73274069 | 7mer-m8 | 73274049 | 73274070 | 140 | -9.03 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000100767.16 | ENST00000644200.1 | PAPLN-212 | hsa-miR-4477b | chr14 | 73274063 | 73274069 | 7mer-m8 | 73274049 | 73274070 | 140 | -9.03 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for PAPLN |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for PAPLN |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_447871 | chr14_73256366_+ | 0.060727230889497 | -0.106646751845664 | 0.0014258279152808 | -0.180384626958076 | 2.51730072838209e-08 | 0.309899288585918 |
| DLPFC | ADediting_447885 | chr14_73256721_+ | 0.824581128960358 | 0.0126398142491068 | 0.120596588635014 | -0.0883476878157056 | 1.61216729339273e-14 | 0.417688891362797 |
| DLPFC | ADediting_447889 | chr14_73256762_+ | 0.53627944366764 | -0.035257047008033 | 0.0283623181836548 | -0.12452878131247 | 9.63474332168874e-09 | 0.318598819063871 |
| DLPFC | ADediting_447894 | chr14_73256804_+ | 0.698453003739853 | -0.0220899390204439 | 0.0279717552004984 | -0.124835614330784 | 1.56979893941122e-13 | 0.402941013500038 |
| DLPFC | ADediting_447904 | chr14_73257111_+ | 0.905418170817237 | -0.00677580278449757 | 0.247535908077171 | -0.0658713122853556 | 3.28781088344123e-10 | 0.347178233647804 |
| DLPFC | ADediting_447909 | chr14_73257206_+ | 0.816761114398895 | -0.0132132044362883 | 0.350503456288315 | -0.0532030295576889 | 1.08713738040061e-08 | 0.317520195376068 |
| DLPFC | ADediting_447922 | chr14_73257944_+ | 0.241180333640906 | 0.0667629045756243 | 0.398754257912907 | -0.0480939024719689 | 1.53581493308632e-22 | 0.516509713305454 |
| DLPFC | ADediting_447923 | chr14_73257947_+ | 0.508802749218629 | 0.0376642503813768 | 0.450882841327537 | -0.0429749639850969 | 3.06117630588941e-15 | 0.428015116070041 |
| DLPFC | ADediting_447924 | chr14_73257961_+ | 0.308190404651614 | 0.0580625318947407 | 0.331583100259567 | -0.0553263789690445 | 6.42741547594302e-22 | 0.509897367162014 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 0.00605373933741371 | 0.155575522626507 | 0.395758916279383 | 0.0483997016392427 | 3.32605876555916e-64 | 0.778269838130104 |
| AC | 5.76141002344907e-17 | 0.496501654374113 | 2.40309545254999e-10 | 0.386780606367622 | 4.55811554290971e-34 | 0.670985189048848 |
| PCC | 0.147182046593971 | 0.105285661524023 | 0.818683798380035 | 0.0166955308295046 | 2.61186397946005e-19 | 0.590150290669706 |
| CER | 0.061650767415303 | -0.152967186402004 | 0.0289182071779861 | -0.178430534253403 | 2.2656718603884e-10 | 0.488528703827746 |
| TCX | 0.428795818387247 | 0.0650815190431442 | 0.0765078533031182 | -0.145074983416317 | 2.18627399825455e-06 | 0.375537659207385 |
| FP | 0.0113892188600102 | 0.189286530314677 | 0.522939696935184 | 0.0481933238264162 | 1.5764869581413e-15 | 0.551094898313867 |
| IFG | 0.289038219870402 | 0.220717562487524 | 0.0659058150367235 | 0.373494174286454 | 0.00714451785793871 | 0.524237414687794 |
| PG | 0.0092248025883765 | 0.190439291924415 | 0.0351245857718405 | 0.154598979423173 | 2.00938656358615e-10 | 0.44480818348913 |
| STG | 0.929973545032222 | 0.00973391570831231 | 0.301106608976137 | -0.114166803992789 | 1.20141221166163e-07 | 0.539327608225103 |
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Relation with AD stages for PAPLN |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 1.07558982058545e-06 | 0.453117816725623 |
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RelatedDrugs for PAPLN |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PAPLN |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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