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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for LAMTOR3 |
 Gene summary |
| Gene information | Gene symbol | LAMTOR3 | Gene ID | 8649 |
| Gene name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | |
| Synonyms | MAP2K1IP1|MAPBP|MAPKSP1|MP1|PRO0633|Ragulator3 | |
| Cytomap | 4q23 | |
| Type of gene | protein-coding | |
| Description | ragulator complex protein LAMTOR3MAPK scaffold protein 1MEK binding partner 1late endosomal/lysosomal adaptor and MAPK and MTOR activator 3mitogen-activated protein kinase kinase 1 interacting protein 1mitogen-activated protein kinase scaffold protei | |
| Modification date | 20200313 | |
| UniProtAcc | Q9UHA4, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for LAMTOR3 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1156205(99880342, -), ADediting_1156206(99880348, -), ADediting_1156207(99880427, -), ADediting_1156208(99880430, -), ADediting_1156209(99880588, -), ADediting_1156210(99880590, -), ADediting_1156211(99880742, -), ADediting_1156212(99880965, -), ADediting_1156213(99880966, -), ADediting_1156214(99880990, -), ADediting_1156215(99881012, -), ADediting_1156216(99881022, -), ADediting_1156217(99881027, -), ADediting_1578678(99881036, -), ADediting_1653781(99880347, -), |
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RNA editing positional annotations for LAMTOR3 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1156205 | chr4_99880342_- | UTR3 |
| ADediting_1156206 | chr4_99880348_- | UTR3 |
| ADediting_1156207 | chr4_99880427_- | UTR3 |
| ADediting_1156208 | chr4_99880430_- | UTR3 |
| ADediting_1156209 | chr4_99880588_- | UTR3 |
| ADediting_1156210 | chr4_99880590_- | UTR3 |
| ADediting_1156211 | chr4_99880742_- | UTR3 |
| ADediting_1156212 | chr4_99880965_- | UTR3 |
| ADediting_1156213 | chr4_99880966_- | UTR3 |
| ADediting_1156214 | chr4_99880990_- | UTR3 |
| ADediting_1156215 | chr4_99881012_- | UTR3 |
| ADediting_1156216 | chr4_99881022_- | UTR3 |
| ADediting_1156217 | chr4_99881027_- | UTR3 |
| ADediting_1578678 | chr4_99881036_- | UTR3 |
| ADediting_1653781 | chr4_99880347_- | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1156205 | chr4_99880342_- | SINE | Alu | Name=AluSz |
| ADediting_1156206 | chr4_99880348_- | SINE | Alu | Name=AluSz |
| ADediting_1156207 | chr4_99880427_- | SINE | Alu | Name=AluSz |
| ADediting_1156208 | chr4_99880430_- | SINE | Alu | Name=AluSz |
| ADediting_1156209 | chr4_99880588_- | SINE | Alu | Name=AluSz |
| ADediting_1156210 | chr4_99880590_- | SINE | Alu | Name=AluSz |
| ADediting_1156211 | chr4_99880742_- | DNA | hAT-Tip100 | Name=MER91C |
| ADediting_1156212 | chr4_99880965_- | SINE | Alu | Name=AluYj4 |
| ADediting_1156213 | chr4_99880966_- | SINE | Alu | Name=AluYj4 |
| ADediting_1156214 | chr4_99880990_- | SINE | Alu | Name=AluYj4 |
| ADediting_1156215 | chr4_99881012_- | SINE | Alu | Name=AluYj4 |
| ADediting_1156216 | chr4_99881022_- | SINE | Alu | Name=AluYj4 |
| ADediting_1156217 | chr4_99881027_- | SINE | Alu | Name=AluYj4 |
| ADediting_1578678 | chr4_99881036_- | SINE | Alu | Name=AluYj4 |
| ADediting_1653781 | chr4_99880347_- | SINE | Alu | Name=AluSz |
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RNA A-to-I editing events in the alternative splicing sites for LAMTOR3 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LAMTOR3 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for LAMTOR3 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for LAMTOR3 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1156205 | chr4_99880342_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-338-3p | chr4 | 99880341 | 99880347 | 7mer-m8 | 99880340 | 99880361 | 140 | -15.44 |
| ADediting_1156205 | chr4_99880342_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4310 | chr4 | 99880342 | 99880348 | 7mer-m8 | 99880341 | 99880356 | 140 | -8.38 |
| ADediting_1156205 | chr4_99880342_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-7157-5p | chr4 | 99880342 | 99880348 | 7mer-m8 | 99880341 | 99880363 | 157 | -22.97 |
| ADediting_1156205 | chr4_99880342_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-7977 | chr4 | 99880339 | 99880345 | 7mer-m8 | 99880338 | 99880355 | 140 | -12.35 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-10a-5p | chr4 | 99880586 | 99880592 | 7mer-m8 | 99880585 | 99880607 | 141 | -12.89 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-10b-5p | chr4 | 99880586 | 99880592 | 7mer-m8 | 99880585 | 99880607 | 140 | -11.43 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-339-5p | chr4 | 99880587 | 99880593 | 7mer-m8 | 99880586 | 99880609 | 148 | -17.37 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-3667-5p | chr4 | 99880583 | 99880589 | 7mer-m8 | 99880582 | 99880608 | 147 | -17.19 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4725-5p | chr4 | 99880585 | 99880591 | 7mer-m8 | 99880584 | 99880604 | 140 | -16.29 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-504-5p | chr4 | 99880585 | 99880591 | 7mer-m8 | 99880584 | 99880604 | 146 | -18.45 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-5699-3p | chr4 | 99880588 | 99880594 | 7mer-m8 | 99880587 | 99880608 | 146 | -16.68 |
| ADediting_1156210 | chr4_99880590_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-340-3p | chr4 | 99880588 | 99880595 | 8mer-1a | 99880588 | 99880607 | 142 | -16.23 |
| ADediting_1156210 | chr4_99880590_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-6827-3p | chr4 | 99880588 | 99880595 | 8mer-1a | 99880588 | 99880608 | 150 | -16.9 |
| ADediting_1156211 | chr4_99880742_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-384 | chr4 | 99880739 | 99880745 | 7mer-m8 | 99880738 | 99880756 | 168 | -15.72 |
| ADediting_1156211 | chr4_99880742_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-516a-3p | chr4 | 99880736 | 99880743 | 8mer-1a | 99880736 | 99880753 | 140 | -15.22 |
| ADediting_1156211 | chr4_99880742_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-516b-3p | chr4 | 99880736 | 99880743 | 8mer-1a | 99880736 | 99880753 | 140 | -15.22 |
| ADediting_1156211 | chr4_99880742_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-7162-5p | chr4 | 99880736 | 99880743 | 8mer-1a | 99880736 | 99880753 | 140 | -12.92 |
| ADediting_1156213 | chr4_99880966_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-130a-5p | chr4 | 99880963 | 99880970 | 8mer-1a | 99880963 | 99880984 | 145 | -8.59 |
| ADediting_1156213 | chr4_99880966_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4753-3p | chr4 | 99880962 | 99880969 | 8mer-1a | 99880962 | 99880983 | 144 | -8.4 |
| ADediting_1156213 | chr4_99880966_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-6809-3p | chr4 | 99880961 | 99880968 | 8mer-1a | 99880961 | 99880981 | 148 | -6.29 |
| ADediting_1156216 | chr4_99881022_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-3064-5p | chr4 | 99881022 | 99881028 | 7mer-m8 | 99881021 | 99881042 | 152 | -19.04 |
| ADediting_1156216 | chr4_99881022_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-3085-3p | chr4 | 99881022 | 99881028 | 7mer-m8 | 99881021 | 99881042 | 145 | -17.8 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1156207 | chr4_99880427_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4684-5p | chr4 | 99880423 | 99880429 | 7mer-m8 | 99880422 | 99880443 | 153 | -15.48 |
| ADediting_1156207 | chr4_99880427_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-593-3p | chr4 | 99880421 | 99880427 | 7mer-1a | 99880421 | 99880439 | 140 | -19.02 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-3664-5p | chr4 | 99880586 | 99880592 | 7mer-m8 | 99880585 | 99880606 | 151 | -15.54 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4432 | chr4 | 99880583 | 99880589 | 7mer-m8 | 99880582 | 99880601 | 150 | -14.43 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4522 | chr4 | 99880585 | 99880591 | 7mer-m8 | 99880584 | 99880604 | 149 | -13.61 |
| ADediting_1156209 | chr4_99880588_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-6888-3p | chr4 | 99880588 | 99880594 | 7mer-m8 | 99880587 | 99880607 | 145 | -12.7 |
| ADediting_1156210 | chr4_99880590_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-3664-5p | chr4 | 99880586 | 99880592 | 7mer-m8 | 99880585 | 99880606 | 151 | -15.54 |
| ADediting_1156210 | chr4_99880590_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4522 | chr4 | 99880585 | 99880591 | 7mer-m8 | 99880584 | 99880604 | 149 | -13.61 |
| ADediting_1156210 | chr4_99880590_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-6818-3p | chr4 | 99880590 | 99880596 | 7mer-m8 | 99880589 | 99880610 | 146 | -13.18 |
| ADediting_1156210 | chr4_99880590_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-6888-3p | chr4 | 99880588 | 99880594 | 7mer-m8 | 99880587 | 99880607 | 145 | -12.7 |
| ADediting_1156211 | chr4_99880742_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-103a-1-5p | chr4 | 99880736 | 99880743 | 8mer-1a | 99880736 | 99880757 | 153 | -15 |
| ADediting_1156211 | chr4_99880742_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-103a-2-5p | chr4 | 99880736 | 99880743 | 8mer-1a | 99880736 | 99880757 | 153 | -13.69 |
| ADediting_1156214 | chr4_99880990_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-367-5p | chr4 | 99880988 | 99880995 | 8mer-1a | 99880988 | 99881009 | 143 | -12.18 |
| ADediting_1156214 | chr4_99880990_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-593-3p | chr4 | 99880985 | 99880991 | 7mer-m8 | 99880984 | 99881002 | 147 | -16.65 |
| ADediting_1156214 | chr4_99880990_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-744-3p | chr4 | 99880990 | 99880996 | 7mer-m8 | 99880989 | 99881010 | 140 | -14.79 |
| ADediting_1156215 | chr4_99881012_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-5693 | chr4 | 99881009 | 99881015 | 7mer-m8 | 99881008 | 99881029 | 142 | -18.31 |
| ADediting_1578678 | chr4_99881036_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-216a-5p | chr4 | 99881034 | 99881040 | 7mer-m8 | 99881033 | 99881054 | 147 | -12.57 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-589-3p | chr4 | 99880704 | 99880710 | 7mer-m8 | 99880703 | 99880726 | 142 | -13.03 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000109270.13 | ENST00000226522.8 | LAMTOR3-201 | hsa-miR-4477b | chr4 | 99881369 | 99881376 | 8mer-1a | 99881369 | 99881395 | 145 | -12.39 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4477b | chr4 | 99881369 | 99881376 | 8mer-1a | 99881369 | 99881395 | 145 | -12.39 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-641 | chr4 | 99879658 | 99879664 | 7mer-m8 | 99879657 | 99879680 | 140 | -12.68 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-641 | chr4 | 99880722 | 99880729 | 8mer-1a | 99880722 | 99880744 | 152 | -12.94 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000109270.13 | ENST00000226522.8 | LAMTOR3-201 | hsa-miR-4775 | chr4 | 99881501 | 99881507 | 7mer-m8 | 99881500 | 99881522 | 159 | -11.28 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-4775 | chr4 | 99881501 | 99881507 | 7mer-m8 | 99881500 | 99881522 | 159 | -11.28 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-5585-3p | chr4 | 99880729 | 99880735 | 7mer-m8 | 99880728 | 99880748 | 142 | -10.34 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000109270.13 | ENST00000226522.8 | LAMTOR3-201 | hsa-miR-151a-3p | chr4 | 99881754 | 99881760 | 7mer-m8 | 99881753 | 99881774 | 153 | -16.24 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-151a-3p | chr4 | 99880864 | 99880870 | 7mer-m8 | 99880863 | 99880882 | 153 | -16.99 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-151a-3p | chr4 | 99881754 | 99881760 | 7mer-m8 | 99881753 | 99881774 | 153 | -16.24 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-641 | chr4 | 99879500 | 99879506 | 7mer-m8 | 99879499 | 99879521 | 152 | -13.7 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-641 | chr4 | 99879500 | 99879506 | 7mer-m8 | 99879499 | 99879521 | 152 | -13.7 |
| ADediting_291761 | chr11_93733708_- | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-1304-3p | chr4 | 99880647 | 99880653 | 7mer-m8 | 99880646 | 99880667 | 146 | -15.39 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000109270.13 | ENST00000226522.8 | LAMTOR3-201 | hsa-miR-5585-3p | chr4 | 99881698 | 99881704 | 7mer-m8 | 99881697 | 99881718 | 140 | -12.47 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-5585-3p | chr4 | 99881698 | 99881704 | 7mer-m8 | 99881697 | 99881718 | 140 | -12.47 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000109270.13 | ENST00000226522.8 | LAMTOR3-201 | hsa-miR-5585-3p | chr4 | 99881698 | 99881704 | 7mer-m8 | 99881697 | 99881718 | 140 | -12.47 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000109270.13 | ENST00000499666.7 | LAMTOR3-202 | hsa-miR-5585-3p | chr4 | 99881698 | 99881704 | 7mer-m8 | 99881697 | 99881718 | 140 | -12.47 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for LAMTOR3 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000499666.7 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1156205 | ENST00000499666.7 | chr4_99880342_- | 2157 | -1148.60 | -1145.80 | -1167.40 |
| ADediting_1653781 | ENST00000499666.7 | chr4_99880347_- | 2152 | -1148.60 | -1145.80 | -1167.40 |
| ADediting_1156206 | ENST00000499666.7 | chr4_99880348_- | 2151 | -1148.30 | -1145.80 | -1167.40 |
| ADediting_1156207 | ENST00000499666.7 | chr4_99880427_- | 2072 | -1146.50 | -1145.80 | -1167.40 |
| ADediting_1156208 | ENST00000499666.7 | chr4_99880430_- | 2069 | -1146.20 | -1145.80 | -1167.40 |
| ADediting_1156209 | ENST00000499666.7 | chr4_99880588_- | 1911 | -1144.90 | -1145.80 | -1167.40 |
| ADediting_1156210 | ENST00000499666.7 | chr4_99880590_- | 1909 | -1152.00 | -1145.80 | -1167.40 |
| ADediting_1156211 | ENST00000499666.7 | chr4_99880742_- | 1757 | -1151.70 | -1145.80 | -1167.40 |
| ADediting_1156212 | ENST00000499666.7 | chr4_99880965_- | 1534 | -1145.40 | -1145.80 | -1167.40 |
| ADediting_1156213 | ENST00000499666.7 | chr4_99880966_- | 1533 | -1145.90 | -1145.80 | -1167.40 |
| ADediting_1156214 | ENST00000499666.7 | chr4_99880990_- | 1509 | -1145.10 | -1145.80 | -1167.40 |
| ADediting_1156215 | ENST00000499666.7 | chr4_99881012_- | 1487 | -1146.10 | -1145.80 | -1167.40 |
| ADediting_1156216 | ENST00000499666.7 | chr4_99881022_- | 1477 | -1145.50 | -1145.80 | -1167.40 |
| ADediting_1156217 | ENST00000499666.7 | chr4_99881027_- | 1472 | -1146.00 | -1145.80 | -1167.40 |
| ADediting_1578678 | ENST00000499666.7 | chr4_99881036_- | 1463 | -1152.50 | -1145.80 | -1167.40 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for LAMTOR3 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1156210 | chr4_99880590_- | 2.99382852214528e-19 | 0.479763901271356 | 3.72683254289456e-11 | 0.364173602674464 | 0.119101402792337 | 0.088703823386193 |
| CER | ADediting_1156210 | chr4_99880590_- | 1.28274368207946e-09 | 0.470102297538377 | 8.88840669546542e-06 | 0.353887348073436 | 0.0201085088860079 | 0.189640616672819 |
| TCX | ADediting_1156210 | chr4_99880590_- | 3.57248607662949e-07 | 0.40137730753756 | 9.03590349719454e-05 | 0.314164171322685 | 0.710526722512137 | 0.0305526812836558 |
| STG | ADediting_1156210 | chr4_99880590_- | 3.69198325701025e-05 | 0.434147474642458 | 3.00440908616038e-07 | 0.524684180814574 | 0.100903963424932 | -0.180223334767914 |
| CER | ADediting_1156216 | chr4_99881022_- | 1.21851802582432e-05 | 0.348792052669915 | 0.000325912268292617 | 0.289542251300313 | 0.160765138649854 | 0.115095779041773 |
| TCX | ADediting_1156216 | chr4_99881022_- | 7.2264148081971e-06 | 0.357183571759483 | 0.00339824390682798 | 0.237719392878786 | 0.413474184549264 | 0.0672596926437707 |
| STG | ADediting_1156216 | chr4_99881022_- | 0.0157033978318043 | 0.262864082511391 | 0.00230995024928478 | 0.328134493954184 | 0.605971025113789 | -0.0570915102018275 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 9.14170879320943e-41 | 0.663913580750059 | 1.14472299007499e-32 | 0.607586949749906 | 0.933494299997584 | 0.00475879856986237 |
| AC | 3.79010524145356e-83 | 0.882340078828545 | 7.97991966799772e-54 | 0.786496523859556 | 9.89736896264207e-15 | 0.463684749092808 |
| PCC | 7.5709273617633e-32 | 0.720311518250613 | 5.16231105280471e-32 | 0.721654481937299 | 0.0158225283606145 | 0.174401993824668 |
| CER | 1.06583853598624e-35 | 0.807174892992391 | 1.69767799271585e-21 | 0.677600926536298 | 0.0155639937648585 | 0.197215071096802 |
| TCX | 3.36606037045779e-39 | 0.829085517956157 | 2.45723302453296e-16 | 0.604876358217948 | 0.198050312504675 | 0.105682930928647 |
| FP | 6.84158806301905e-10 | 0.441561872792182 | 3.52896202559822e-16 | 0.561522728941871 | 0.125925589072685 | -0.115135314875411 |
| IFG | 0.016193249326189 | 0.475881681033887 | 0.0699436537431305 | 0.36844526672323 | 0.0399239868092649 | -0.413479981080522 |
| PG | 1.67607047794726e-46 | 0.82020602479924 | 1.87248635774228e-26 | 0.678655153315926 | 0.290348027652034 | -0.0779366857679197 |
| STG | 1.38835879839096e-14 | 0.718683318921631 | 2.30411101736074e-14 | 0.714535469371322 | 0.082975808758897 | -0.190278195017142 |
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Relation with AD stages for LAMTOR3 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for LAMTOR3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for LAMTOR3 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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