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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for FBF1 |
 Gene summary |
| Gene information | Gene symbol | FBF1 | Gene ID | 85302 |
| Gene name | Fas binding factor 1 | |
| Synonyms | Alb|FBF-1 | |
| Cytomap | 17q25.1 | |
| Type of gene | protein-coding | |
| Description | fas-binding factor 1Fas (TNFRSF6) binding factor 1Fas binding protein 1albatrossprotein albatross | |
| Modification date | 20200320 | |
| UniProtAcc | Q8TES7, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for FBF1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_664637(75912891, -), ADediting_664638(75912892, -), ADediting_664639(75912916, -), ADediting_664640(75912918, -), ADediting_664641(75912928, -), ADediting_664642(75912931, -), ADediting_664643(75912932, -), ADediting_664644(75912945, -), ADediting_664645(75912983, -), ADediting_664646(75913014, -), ADediting_664647(75913251, -), ADediting_664648(75913260, -), ADediting_664649(75913286, -), ADediting_664650(75913313, -), ADediting_664651(75913316, -), ADediting_664652(75913321, -), ADediting_664653(75913346, -), ADediting_664654(75913347, -), ADediting_664655(75913351, -), ADediting_664656(75913366, -), ADediting_664657(75913375, -), ADediting_664658(75913423, -), ADediting_664659(75920350, -), ADediting_664660(75923956, -), ADediting_664661(75923995, -), ADediting_664662(75923996, -), ADediting_664663(75924102, -), ADediting_664664(75924105, -), ADediting_664665(75924131, -), ADediting_664666(75924132, -), ADediting_664667(75924200, -), ADediting_664668(75924606, -), ADediting_664669(75924610, -), ADediting_664670(75924642, -), ADediting_664671(75924648, -), ADediting_664672(75924656, -), ADediting_664673(75924696, -), ADediting_664674(75924715, -), ADediting_664675(75924728, -), ADediting_664676(75928686, -), ADediting_664677(75928699, -), ADediting_664678(75928708, -), ADediting_664679(75928713, -), ADediting_664680(75928732, -), ADediting_664681(75928901, -), ADediting_664682(75928915, -), ADediting_664683(75928918, -), ADediting_664684(75928923, -), ADediting_664685(75928928, -), ADediting_664686(75928937, -), ADediting_664687(75928963, -), ADediting_664688(75928964, -), ADediting_664689(75929066, -), ADediting_664690(75929083, -), ADediting_664691(75929102, -), ADediting_664692(75929129, -), ADediting_664693(75929214, -), ADediting_664694(75929225, -), ADediting_664695(75929241, -), ADediting_664696(75929253, -), ADediting_664697(75929254, -), ADediting_664698(75929273, -), ADediting_664699(75929274, -), ADediting_664700(75929279, -), ADediting_664701(75929312, -), ADediting_664702(75929331, -), ADediting_664703(75933485, -), ADediting_664704(75933519, -), ADediting_664705(75934369, -), ADediting_664706(75934378, -), ADediting_664707(75934449, -), ADediting_664708(75934453, -), ADediting_664709(75934474, -), ADediting_664710(75934478, -), ADediting_664711(75934484, -), ADediting_664712(75934534, -), ADediting_664713(75934542, -), ADediting_664714(75934622, -), ADediting_664715(75934840, -), ADediting_664716(75934866, -), ADediting_664717(75935225, -), ADediting_664718(75935241, -), ADediting_664719(75935261, -), ADediting_664720(75935267, -), ADediting_664721(75935276, -), ADediting_664722(75935293, -), ADediting_664723(75935329, -), ADediting_664724(75935362, -), ADediting_664725(75935370, -), ADediting_664726(75935372, -), ADediting_664727(75935387, -), ADediting_664728(75935388, -), ADediting_664729(75935396, -), ADediting_664730(75935423, -), ADediting_664731(75936254, -), ADediting_664732(75936367, -), ADediting_664733(75936623, -), ADediting_664734(75937299, -), ADediting_664735(75937303, -), ADediting_664736(75937309, -), ADediting_664737(75937335, -), ADediting_664738(75937461, -), ADediting_664739(75938316, -), ADediting_664740(75938344, -), ADediting_664741(75938369, -), ADediting_664742(75938389, -), ADediting_664743(75938398, -), ADediting_664744(75938410, -), ADediting_664745(75938411, -), ADediting_664746(75938415, -), ADediting_664747(75938437, -), ADediting_664748(75938456, -), ADediting_664749(75938472, -), ADediting_664750(75938473, -), ADediting_664751(75938474, -), ADediting_664752(75938487, -), ADediting_664753(75938599, -), ADediting_664754(75938605, -), ADediting_664755(75938619, -), ADediting_664756(75938643, -), ADediting_664757(75938647, -), ADediting_664758(75938834, -), ADediting_664759(75939040, -), ADediting_664760(75939051, -), ADediting_664761(75939061, -), ADediting_664762(75939148, -), ADediting_664763(75939179, -), ADediting_664764(75939184, -), ADediting_664765(75939209, -), ADediting_664766(75939642, -), ADediting_664767(75939647, -), ADediting_664768(75939652, -), ADediting_664769(75939668, -), ADediting_664770(75939675, -), ADediting_664771(75939975, -), ADediting_664772(75939976, -), ADediting_664773(75939983, -), ADediting_664774(75939998, -), ADediting_664775(75940006, -), ADediting_664776(75940013, -), ADediting_664777(75940014, -), ADediting_664778(75940061, -), ADediting_664779(75940067, -), ADediting_664780(75940074, -), ADediting_664781(75940078, -), ADediting_664782(75940084, -), ADediting_664783(75940109, -), ADediting_664784(75940110, -), ADediting_664785(75940113, -), ADediting_664786(75940114, -), ADediting_664787(75940115, -), ADediting_664788(75940119, -), ADediting_664789(75940139, -), ADediting_664790(75940145, -), ADediting_664791(75940147, -), ADediting_664792(75940214, -), ADediting_664793(75940220, -), ADediting_664794(75940272, -), ADediting_664795(75940278, -), ADediting_664796(75940280, -), ADediting_664797(75940295, -), ADediting_664798(75940455, -), ADediting_664799(75940459, -), ADediting_664800(75940483, -), ADediting_664801(75940506, -), ADediting_664802(75940507, -), ADediting_664803(75940528, -), ADediting_664804(75940529, -), ADediting_664805(75940547, -), ADediting_1549258(75911158, -), ADediting_1549259(75911170, -), ADediting_1549260(75924655, -), ADediting_1549261(75929226, -), ADediting_1549262(75934309, -), ADediting_1549263(75936553, -), ADediting_1549264(75936563, -), ADediting_1549265(75936674, -), ADediting_1549266(75936782, -), ADediting_1549267(75938744, -), ADediting_1549268(75940248, -), ADediting_1549269(75940378, -), ADediting_1549270(75940522, -), ADediting_1628749(75924654, -), |
Top |
RNA editing positional annotations for FBF1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_664659 | chr17_75920350_- | nonsynonymous SNV | ENST00000636174.1 | c.A1754G | p.Q585R | 0.017 | 0.041 | -2.41 |
| ADediting_664659 | chr17_75920350_- | nonsynonymous SNV | ENST00000586717.5 | c.A1712G | p.Q571R | 0.017 | 0.041 | -2.41 |
| ADediting_664659 | chr17_75920350_- | nonsynonymous SNV | ENST00000592193.6 | c.A1751G | p.Q584R | 0.017 | 0.041 | -2.41 |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_664637 | chr17_75912891_- | intronic |
| ADediting_664638 | chr17_75912892_- | intronic |
| ADediting_664639 | chr17_75912916_- | intronic |
| ADediting_664640 | chr17_75912918_- | intronic |
| ADediting_664641 | chr17_75912928_- | intronic |
| ADediting_664642 | chr17_75912931_- | intronic |
| ADediting_664643 | chr17_75912932_- | intronic |
| ADediting_664644 | chr17_75912945_- | intronic |
| ADediting_664645 | chr17_75912983_- | intronic |
| ADediting_664646 | chr17_75913014_- | intronic |
| ADediting_664647 | chr17_75913251_- | intronic |
| ADediting_664648 | chr17_75913260_- | intronic |
| ADediting_664649 | chr17_75913286_- | intronic |
| ADediting_664650 | chr17_75913313_- | intronic |
| ADediting_664651 | chr17_75913316_- | intronic |
| ADediting_664652 | chr17_75913321_- | intronic |
| ADediting_664653 | chr17_75913346_- | intronic |
| ADediting_664654 | chr17_75913347_- | intronic |
| ADediting_664655 | chr17_75913351_- | intronic |
| ADediting_664656 | chr17_75913366_- | intronic |
| ADediting_664657 | chr17_75913375_- | intronic |
| ADediting_664658 | chr17_75913423_- | intronic |
| ADediting_664659 | chr17_75920350_- | exonic |
| ADediting_664660 | chr17_75923956_- | intronic |
| ADediting_664661 | chr17_75923995_- | intronic |
| ADediting_664662 | chr17_75923996_- | intronic |
| ADediting_664663 | chr17_75924102_- | intronic |
| ADediting_664664 | chr17_75924105_- | intronic |
| ADediting_664665 | chr17_75924131_- | intronic |
| ADediting_664666 | chr17_75924132_- | intronic |
| ADediting_664667 | chr17_75924200_- | intronic |
| ADediting_664668 | chr17_75924606_- | intronic |
| ADediting_664669 | chr17_75924610_- | intronic |
| ADediting_664670 | chr17_75924642_- | intronic |
| ADediting_664671 | chr17_75924648_- | intronic |
| ADediting_664672 | chr17_75924656_- | intronic |
| ADediting_664673 | chr17_75924696_- | intronic |
| ADediting_664674 | chr17_75924715_- | intronic |
| ADediting_664675 | chr17_75924728_- | intronic |
| ADediting_664676 | chr17_75928686_- | intronic |
| ADediting_664677 | chr17_75928699_- | intronic |
| ADediting_664678 | chr17_75928708_- | intronic |
| ADediting_664679 | chr17_75928713_- | intronic |
| ADediting_664680 | chr17_75928732_- | intronic |
| ADediting_664681 | chr17_75928901_- | intronic |
| ADediting_664682 | chr17_75928915_- | intronic |
| ADediting_664683 | chr17_75928918_- | intronic |
| ADediting_664684 | chr17_75928923_- | intronic |
| ADediting_664685 | chr17_75928928_- | intronic |
| ADediting_664686 | chr17_75928937_- | intronic |
| ADediting_664687 | chr17_75928963_- | intronic |
| ADediting_664688 | chr17_75928964_- | intronic |
| ADediting_664689 | chr17_75929066_- | intronic |
| ADediting_664690 | chr17_75929083_- | intronic |
| ADediting_664691 | chr17_75929102_- | intronic |
| ADediting_664692 | chr17_75929129_- | intronic |
| ADediting_664693 | chr17_75929214_- | intronic |
| ADediting_664694 | chr17_75929225_- | intronic |
| ADediting_664695 | chr17_75929241_- | intronic |
| ADediting_664696 | chr17_75929253_- | intronic |
| ADediting_664697 | chr17_75929254_- | intronic |
| ADediting_664698 | chr17_75929273_- | intronic |
| ADediting_664699 | chr17_75929274_- | intronic |
| ADediting_664700 | chr17_75929279_- | intronic |
| ADediting_664701 | chr17_75929312_- | intronic |
| ADediting_664702 | chr17_75929331_- | intronic |
| ADediting_664703 | chr17_75933485_- | intronic |
| ADediting_664704 | chr17_75933519_- | intronic |
| ADediting_664705 | chr17_75934369_- | intronic |
| ADediting_664706 | chr17_75934378_- | intronic |
| ADediting_664707 | chr17_75934449_- | intronic |
| ADediting_664708 | chr17_75934453_- | intronic |
| ADediting_664709 | chr17_75934474_- | intronic |
| ADediting_664710 | chr17_75934478_- | intronic |
| ADediting_664711 | chr17_75934484_- | intronic |
| ADediting_664712 | chr17_75934534_- | intronic |
| ADediting_664713 | chr17_75934542_- | intronic |
| ADediting_664714 | chr17_75934622_- | intronic |
| ADediting_664715 | chr17_75934840_- | intronic |
| ADediting_664716 | chr17_75934866_- | intronic |
| ADediting_664717 | chr17_75935225_- | intronic |
| ADediting_664718 | chr17_75935241_- | intronic |
| ADediting_664719 | chr17_75935261_- | intronic |
| ADediting_664720 | chr17_75935267_- | intronic |
| ADediting_664721 | chr17_75935276_- | intronic |
| ADediting_664722 | chr17_75935293_- | intronic |
| ADediting_664723 | chr17_75935329_- | intronic |
| ADediting_664724 | chr17_75935362_- | intronic |
| ADediting_664725 | chr17_75935370_- | intronic |
| ADediting_664726 | chr17_75935372_- | intronic |
| ADediting_664727 | chr17_75935387_- | intronic |
| ADediting_664728 | chr17_75935388_- | intronic |
| ADediting_664729 | chr17_75935396_- | intronic |
| ADediting_664730 | chr17_75935423_- | intronic |
| ADediting_664731 | chr17_75936254_- | intronic |
| ADediting_664732 | chr17_75936367_- | intronic |
| ADediting_664733 | chr17_75936623_- | intronic |
| ADediting_664734 | chr17_75937299_- | intronic |
| ADediting_664735 | chr17_75937303_- | intronic |
| ADediting_664736 | chr17_75937309_- | intronic |
| ADediting_664737 | chr17_75937335_- | intronic |
| ADediting_664738 | chr17_75937461_- | intronic |
| ADediting_664739 | chr17_75938316_- | intronic |
| ADediting_664740 | chr17_75938344_- | intronic |
| ADediting_664741 | chr17_75938369_- | intronic |
| ADediting_664742 | chr17_75938389_- | intronic |
| ADediting_664743 | chr17_75938398_- | intronic |
| ADediting_664744 | chr17_75938410_- | intronic |
| ADediting_664745 | chr17_75938411_- | intronic |
| ADediting_664746 | chr17_75938415_- | intronic |
| ADediting_664747 | chr17_75938437_- | intronic |
| ADediting_664748 | chr17_75938456_- | intronic |
| ADediting_664749 | chr17_75938472_- | intronic |
| ADediting_664750 | chr17_75938473_- | intronic |
| ADediting_664751 | chr17_75938474_- | intronic |
| ADediting_664752 | chr17_75938487_- | intronic |
| ADediting_664753 | chr17_75938599_- | intronic |
| ADediting_664754 | chr17_75938605_- | intronic |
| ADediting_664755 | chr17_75938619_- | intronic |
| ADediting_664756 | chr17_75938643_- | intronic |
| ADediting_664757 | chr17_75938647_- | intronic |
| ADediting_664758 | chr17_75938834_- | intronic |
| ADediting_664759 | chr17_75939040_- | intronic |
| ADediting_664760 | chr17_75939051_- | intronic |
| ADediting_664761 | chr17_75939061_- | intronic |
| ADediting_664762 | chr17_75939148_- | intronic |
| ADediting_664763 | chr17_75939179_- | intronic |
| ADediting_664764 | chr17_75939184_- | intronic |
| ADediting_664765 | chr17_75939209_- | intronic |
| ADediting_664766 | chr17_75939642_- | intronic |
| ADediting_664767 | chr17_75939647_- | intronic |
| ADediting_664768 | chr17_75939652_- | intronic |
| ADediting_664769 | chr17_75939668_- | intronic |
| ADediting_664770 | chr17_75939675_- | intronic |
| ADediting_664771 | chr17_75939975_- | intronic |
| ADediting_664772 | chr17_75939976_- | intronic |
| ADediting_664773 | chr17_75939983_- | intronic |
| ADediting_664774 | chr17_75939998_- | intronic |
| ADediting_664775 | chr17_75940006_- | intronic |
| ADediting_664776 | chr17_75940013_- | intronic |
| ADediting_664777 | chr17_75940014_- | intronic |
| ADediting_664778 | chr17_75940061_- | intronic |
| ADediting_664779 | chr17_75940067_- | intronic |
| ADediting_664780 | chr17_75940074_- | intronic |
| ADediting_664781 | chr17_75940078_- | intronic |
| ADediting_664782 | chr17_75940084_- | intronic |
| ADediting_664783 | chr17_75940109_- | intronic |
| ADediting_664784 | chr17_75940110_- | intronic |
| ADediting_664785 | chr17_75940113_- | intronic |
| ADediting_664786 | chr17_75940114_- | intronic |
| ADediting_664787 | chr17_75940115_- | intronic |
| ADediting_664788 | chr17_75940119_- | intronic |
| ADediting_664789 | chr17_75940139_- | intronic |
| ADediting_664790 | chr17_75940145_- | intronic |
| ADediting_664791 | chr17_75940147_- | intronic |
| ADediting_664792 | chr17_75940214_- | intronic |
| ADediting_664793 | chr17_75940220_- | intronic |
| ADediting_664794 | chr17_75940272_- | intronic |
| ADediting_664795 | chr17_75940278_- | intronic |
| ADediting_664796 | chr17_75940280_- | intronic |
| ADediting_664797 | chr17_75940295_- | intronic |
| ADediting_664798 | chr17_75940455_- | intronic |
| ADediting_664799 | chr17_75940459_- | intronic |
| ADediting_664800 | chr17_75940483_- | intronic |
| ADediting_664801 | chr17_75940506_- | intronic |
| ADediting_664802 | chr17_75940507_- | intronic |
| ADediting_664803 | chr17_75940528_- | intronic |
| ADediting_664804 | chr17_75940529_- | intronic |
| ADediting_664805 | chr17_75940547_- | intronic |
| ADediting_1549258 | chr17_75911158_- | intronic |
| ADediting_1549259 | chr17_75911170_- | intronic |
| ADediting_1549260 | chr17_75924655_- | intronic |
| ADediting_1549261 | chr17_75929226_- | intronic |
| ADediting_1549262 | chr17_75934309_- | intronic |
| ADediting_1549263 | chr17_75936553_- | intronic |
| ADediting_1549264 | chr17_75936563_- | intronic |
| ADediting_1549265 | chr17_75936674_- | intronic |
| ADediting_1549266 | chr17_75936782_- | intronic |
| ADediting_1549267 | chr17_75938744_- | intronic |
| ADediting_1549268 | chr17_75940248_- | intronic |
| ADediting_1549269 | chr17_75940378_- | intronic |
| ADediting_1549270 | chr17_75940522_- | intronic |
| ADediting_1628749 | chr17_75924654_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_664637 | chr17_75912891_- | SINE | Alu | Name=AluSq2 |
| ADediting_664638 | chr17_75912892_- | SINE | Alu | Name=AluSq2 |
| ADediting_664639 | chr17_75912916_- | SINE | Alu | Name=AluSq2 |
| ADediting_664640 | chr17_75912918_- | SINE | Alu | Name=AluSq2 |
| ADediting_664641 | chr17_75912928_- | SINE | Alu | Name=AluSq2 |
| ADediting_664642 | chr17_75912931_- | SINE | Alu | Name=AluSq2 |
| ADediting_664643 | chr17_75912932_- | SINE | Alu | Name=AluSq2 |
| ADediting_664644 | chr17_75912945_- | SINE | Alu | Name=AluSq2 |
| ADediting_664645 | chr17_75912983_- | SINE | Alu | Name=AluSq2 |
| ADediting_664646 | chr17_75913014_- | SINE | Alu | Name=AluSq2 |
| ADediting_664647 | chr17_75913251_- | SINE | Alu | Name=AluSx1 |
| ADediting_664648 | chr17_75913260_- | SINE | Alu | Name=AluSx1 |
| ADediting_664649 | chr17_75913286_- | SINE | Alu | Name=AluSx1 |
| ADediting_664650 | chr17_75913313_- | SINE | Alu | Name=AluSx1 |
| ADediting_664651 | chr17_75913316_- | SINE | Alu | Name=AluSx1 |
| ADediting_664652 | chr17_75913321_- | SINE | Alu | Name=AluSx1 |
| ADediting_664653 | chr17_75913346_- | SINE | Alu | Name=AluSx1 |
| ADediting_664654 | chr17_75913347_- | SINE | Alu | Name=AluSx1 |
| ADediting_664655 | chr17_75913351_- | SINE | Alu | Name=AluSx1 |
| ADediting_664656 | chr17_75913366_- | SINE | Alu | Name=AluSx1 |
| ADediting_664657 | chr17_75913375_- | SINE | Alu | Name=AluSx1 |
| ADediting_664658 | chr17_75913423_- | SINE | Alu | Name=AluSx1 |
| ADediting_664660 | chr17_75923956_- | SINE | Alu | Name=AluSx1 |
| ADediting_664661 | chr17_75923995_- | SINE | Alu | Name=AluSx1 |
| ADediting_664662 | chr17_75923996_- | SINE | Alu | Name=AluSx1 |
| ADediting_664663 | chr17_75924102_- | SINE | Alu | Name=AluSx1 |
| ADediting_664664 | chr17_75924105_- | SINE | Alu | Name=AluSx1 |
| ADediting_664665 | chr17_75924131_- | SINE | Alu | Name=AluSx1 |
| ADediting_664666 | chr17_75924132_- | SINE | Alu | Name=AluSx1 |
| ADediting_664667 | chr17_75924200_- | SINE | Alu | Name=AluSx1 |
| ADediting_664668 | chr17_75924606_- | SINE | Alu | Name=AluSx1 |
| ADediting_664669 | chr17_75924610_- | SINE | Alu | Name=AluSx1 |
| ADediting_664670 | chr17_75924642_- | SINE | Alu | Name=AluSx1 |
| ADediting_664671 | chr17_75924648_- | SINE | Alu | Name=AluSx1 |
| ADediting_664672 | chr17_75924656_- | SINE | Alu | Name=AluSx1 |
| ADediting_664673 | chr17_75924696_- | SINE | Alu | Name=AluSx1 |
| ADediting_664674 | chr17_75924715_- | SINE | Alu | Name=AluSx1 |
| ADediting_664675 | chr17_75924728_- | SINE | Alu | Name=AluSx1 |
| ADediting_664676 | chr17_75928686_- | SINE | Alu | Name=AluSc |
| ADediting_664677 | chr17_75928699_- | SINE | Alu | Name=AluSc |
| ADediting_664678 | chr17_75928708_- | SINE | Alu | Name=AluSc |
| ADediting_664679 | chr17_75928713_- | SINE | Alu | Name=AluSc |
| ADediting_664680 | chr17_75928732_- | SINE | Alu | Name=AluSc |
| ADediting_664681 | chr17_75928901_- | SINE | Alu | Name=AluJo |
| ADediting_664682 | chr17_75928915_- | SINE | Alu | Name=AluJo |
| ADediting_664683 | chr17_75928918_- | SINE | Alu | Name=AluJo |
| ADediting_664684 | chr17_75928923_- | SINE | Alu | Name=AluJo |
| ADediting_664685 | chr17_75928928_- | SINE | Alu | Name=AluJo |
| ADediting_664686 | chr17_75928937_- | SINE | Alu | Name=AluJo |
| ADediting_664687 | chr17_75928963_- | SINE | Alu | Name=AluJo |
| ADediting_664688 | chr17_75928964_- | SINE | Alu | Name=AluJo |
| ADediting_664689 | chr17_75929066_- | SINE | Alu | Name=AluJo |
| ADediting_664690 | chr17_75929083_- | SINE | Alu | Name=AluJo |
| ADediting_664691 | chr17_75929102_- | SINE | Alu | Name=AluJo |
| ADediting_664692 | chr17_75929129_- | SINE | Alu | Name=AluJo |
| ADediting_664693 | chr17_75929214_- | SINE | Alu | Name=AluJo |
| ADediting_664694 | chr17_75929225_- | SINE | Alu | Name=AluJo |
| ADediting_664695 | chr17_75929241_- | SINE | Alu | Name=AluJo |
| ADediting_664696 | chr17_75929253_- | SINE | Alu | Name=AluJo |
| ADediting_664697 | chr17_75929254_- | SINE | Alu | Name=AluJo |
| ADediting_664698 | chr17_75929273_- | SINE | Alu | Name=AluJo |
| ADediting_664699 | chr17_75929274_- | SINE | Alu | Name=AluJo |
| ADediting_664700 | chr17_75929279_- | SINE | Alu | Name=AluJo |
| ADediting_664701 | chr17_75929312_- | SINE | Alu | Name=AluJo |
| ADediting_664702 | chr17_75929331_- | SINE | Alu | Name=AluJo |
| ADediting_664703 | chr17_75933485_- | SINE | Alu | Name=AluSx1 |
| ADediting_664704 | chr17_75933519_- | SINE | Alu | Name=AluSx1 |
| ADediting_664705 | chr17_75934369_- | SINE | Alu | Name=AluSz6 |
| ADediting_664706 | chr17_75934378_- | SINE | Alu | Name=AluSz6 |
| ADediting_664707 | chr17_75934449_- | SINE | Alu | Name=AluSz6 |
| ADediting_664708 | chr17_75934453_- | SINE | Alu | Name=AluSz6 |
| ADediting_664709 | chr17_75934474_- | SINE | Alu | Name=AluSz6 |
| ADediting_664710 | chr17_75934478_- | SINE | Alu | Name=AluSz6 |
| ADediting_664711 | chr17_75934484_- | SINE | Alu | Name=AluSz6 |
| ADediting_664712 | chr17_75934534_- | SINE | Alu | Name=AluSz6 |
| ADediting_664713 | chr17_75934542_- | SINE | Alu | Name=AluSz6 |
| ADediting_664714 | chr17_75934622_- | SINE | Alu | Name=AluSp |
| ADediting_664715 | chr17_75934840_- | SINE | Alu | Name=AluSp |
| ADediting_664716 | chr17_75934866_- | SINE | Alu | Name=AluSp |
| ADediting_664717 | chr17_75935225_- | SINE | Alu | Name=AluSx3 |
| ADediting_664718 | chr17_75935241_- | SINE | Alu | Name=AluSx3 |
| ADediting_664719 | chr17_75935261_- | SINE | Alu | Name=AluSx3 |
| ADediting_664720 | chr17_75935267_- | SINE | Alu | Name=AluSx3 |
| ADediting_664721 | chr17_75935276_- | SINE | Alu | Name=AluSx3 |
| ADediting_664722 | chr17_75935293_- | SINE | Alu | Name=AluSx3 |
| ADediting_664723 | chr17_75935329_- | SINE | Alu | Name=AluSx3 |
| ADediting_664724 | chr17_75935362_- | SINE | Alu | Name=AluSx3 |
| ADediting_664725 | chr17_75935370_- | SINE | Alu | Name=AluSx3 |
| ADediting_664726 | chr17_75935372_- | SINE | Alu | Name=AluSx3 |
| ADediting_664727 | chr17_75935387_- | SINE | Alu | Name=AluSx3 |
| ADediting_664728 | chr17_75935388_- | SINE | Alu | Name=AluSx3 |
| ADediting_664729 | chr17_75935396_- | SINE | Alu | Name=AluSx3 |
| ADediting_664730 | chr17_75935423_- | SINE | Alu | Name=AluSx3 |
| ADediting_664731 | chr17_75936254_- | SINE | Alu | Name=AluSx3 |
| ADediting_664732 | chr17_75936367_- | SINE | Alu | Name=AluSx |
| ADediting_664733 | chr17_75936623_- | SINE | Alu | Name=AluSx |
| ADediting_664734 | chr17_75937299_- | SINE | Alu | Name=AluY |
| ADediting_664735 | chr17_75937303_- | SINE | Alu | Name=AluY |
| ADediting_664736 | chr17_75937309_- | SINE | Alu | Name=AluY |
| ADediting_664737 | chr17_75937335_- | SINE | Alu | Name=AluY |
| ADediting_664738 | chr17_75937461_- | SINE | Alu | Name=AluY |
| ADediting_664739 | chr17_75938316_- | SINE | Alu | Name=AluSx |
| ADediting_664740 | chr17_75938344_- | SINE | Alu | Name=AluSx |
| ADediting_664741 | chr17_75938369_- | SINE | Alu | Name=AluSx |
| ADediting_664742 | chr17_75938389_- | SINE | Alu | Name=AluSx |
| ADediting_664743 | chr17_75938398_- | SINE | Alu | Name=AluSx |
| ADediting_664744 | chr17_75938410_- | SINE | Alu | Name=AluSx |
| ADediting_664745 | chr17_75938411_- | SINE | Alu | Name=AluSx |
| ADediting_664746 | chr17_75938415_- | SINE | Alu | Name=AluSx |
| ADediting_664747 | chr17_75938437_- | SINE | Alu | Name=AluSx |
| ADediting_664748 | chr17_75938456_- | SINE | Alu | Name=AluSx |
| ADediting_664749 | chr17_75938472_- | SINE | Alu | Name=AluSx |
| ADediting_664750 | chr17_75938473_- | SINE | Alu | Name=AluSx |
| ADediting_664751 | chr17_75938474_- | SINE | Alu | Name=AluSx |
| ADediting_664752 | chr17_75938487_- | SINE | Alu | Name=AluSx |
| ADediting_664753 | chr17_75938599_- | SINE | Alu | Name=AluSx1 |
| ADediting_664754 | chr17_75938605_- | SINE | Alu | Name=AluSx1 |
| ADediting_664755 | chr17_75938619_- | SINE | Alu | Name=AluSx1 |
| ADediting_664756 | chr17_75938643_- | SINE | Alu | Name=AluSx1 |
| ADediting_664757 | chr17_75938647_- | SINE | Alu | Name=AluSx1 |
| ADediting_664758 | chr17_75938834_- | SINE | Alu | Name=AluSx1 |
| ADediting_664759 | chr17_75939040_- | SINE | Alu | Name=AluSz |
| ADediting_664760 | chr17_75939051_- | SINE | Alu | Name=AluSz |
| ADediting_664761 | chr17_75939061_- | SINE | Alu | Name=AluSz |
| ADediting_664762 | chr17_75939148_- | SINE | Alu | Name=AluSz |
| ADediting_664763 | chr17_75939179_- | SINE | Alu | Name=AluSz |
| ADediting_664764 | chr17_75939184_- | SINE | Alu | Name=AluSz |
| ADediting_664765 | chr17_75939209_- | SINE | Alu | Name=AluSz |
| ADediting_664766 | chr17_75939642_- | SINE | Alu | Name=FLAM_C |
| ADediting_664767 | chr17_75939647_- | SINE | Alu | Name=FLAM_C |
| ADediting_664768 | chr17_75939652_- | SINE | Alu | Name=FLAM_C |
| ADediting_664769 | chr17_75939668_- | SINE | Alu | Name=FLAM_C |
| ADediting_664770 | chr17_75939675_- | SINE | Alu | Name=FLAM_C |
| ADediting_664771 | chr17_75939975_- | SINE | Alu | Name=AluSg |
| ADediting_664772 | chr17_75939976_- | SINE | Alu | Name=AluSg |
| ADediting_664773 | chr17_75939983_- | SINE | Alu | Name=AluSg |
| ADediting_664774 | chr17_75939998_- | SINE | Alu | Name=AluSg |
| ADediting_664775 | chr17_75940006_- | SINE | Alu | Name=AluSg |
| ADediting_664776 | chr17_75940013_- | SINE | Alu | Name=AluSg |
| ADediting_664777 | chr17_75940014_- | SINE | Alu | Name=AluSg |
| ADediting_664778 | chr17_75940061_- | SINE | Alu | Name=AluSg |
| ADediting_664779 | chr17_75940067_- | SINE | Alu | Name=AluSg |
| ADediting_664780 | chr17_75940074_- | SINE | Alu | Name=AluSg |
| ADediting_664781 | chr17_75940078_- | SINE | Alu | Name=AluSg |
| ADediting_664782 | chr17_75940084_- | SINE | Alu | Name=AluSg |
| ADediting_664783 | chr17_75940109_- | SINE | Alu | Name=AluSg |
| ADediting_664784 | chr17_75940110_- | SINE | Alu | Name=AluSg |
| ADediting_664785 | chr17_75940113_- | SINE | Alu | Name=AluSg |
| ADediting_664786 | chr17_75940114_- | SINE | Alu | Name=AluSg |
| ADediting_664787 | chr17_75940115_- | SINE | Alu | Name=AluSg |
| ADediting_664788 | chr17_75940119_- | SINE | Alu | Name=AluSg |
| ADediting_664789 | chr17_75940139_- | SINE | Alu | Name=AluSg |
| ADediting_664790 | chr17_75940145_- | SINE | Alu | Name=AluSg |
| ADediting_664791 | chr17_75940147_- | SINE | Alu | Name=AluSg |
| ADediting_664792 | chr17_75940214_- | SINE | Alu | Name=AluSg |
| ADediting_664793 | chr17_75940220_- | SINE | Alu | Name=AluSg |
| ADediting_664794 | chr17_75940272_- | SINE | Alu | Name=AluJr |
| ADediting_664795 | chr17_75940278_- | SINE | Alu | Name=AluJr |
| ADediting_664796 | chr17_75940280_- | SINE | Alu | Name=AluJr |
| ADediting_664797 | chr17_75940295_- | SINE | Alu | Name=AluJr |
| ADediting_664798 | chr17_75940455_- | SINE | Alu | Name=AluJr |
| ADediting_664799 | chr17_75940459_- | SINE | Alu | Name=AluJr |
| ADediting_664800 | chr17_75940483_- | SINE | Alu | Name=AluJr |
| ADediting_664801 | chr17_75940506_- | SINE | Alu | Name=AluJr |
| ADediting_664802 | chr17_75940507_- | SINE | Alu | Name=AluJr |
| ADediting_664803 | chr17_75940528_- | SINE | Alu | Name=AluJr |
| ADediting_664804 | chr17_75940529_- | SINE | Alu | Name=AluJr |
| ADediting_664805 | chr17_75940547_- | SINE | Alu | Name=AluJr |
| ADediting_1549258 | chr17_75911158_- | SINE | Alu | Name=FLAM_C |
| ADediting_1549259 | chr17_75911170_- | SINE | Alu | Name=FLAM_C |
| ADediting_1549260 | chr17_75924655_- | SINE | Alu | Name=AluSx1 |
| ADediting_1549261 | chr17_75929226_- | SINE | Alu | Name=AluJo |
| ADediting_1549262 | chr17_75934309_- | SINE | Alu | Name=AluSz6 |
| ADediting_1549263 | chr17_75936553_- | SINE | Alu | Name=AluSx |
| ADediting_1549264 | chr17_75936563_- | SINE | Alu | Name=AluSx |
| ADediting_1549265 | chr17_75936674_- | SINE | Alu | Name=AluSx |
| ADediting_1549267 | chr17_75938744_- | SINE | Alu | Name=AluSx1 |
| ADediting_1549268 | chr17_75940248_- | SINE | Alu | Name=AluJr |
| ADediting_1549269 | chr17_75940378_- | SINE | Alu | Name=AluJr |
| ADediting_1549270 | chr17_75940522_- | SINE | Alu | Name=AluJr |
| ADediting_1628749 | chr17_75924654_- | SINE | Alu | Name=AluSx1 |
Top |
RNA A-to-I editing events in the alternative splicing sites for FBF1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for FBF1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for FBF1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for FBF1 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000188878.19 | ENST00000586631.2 | FBF1-204 | hsa-miR-5581-3p | chr17 | 75937894 | 75937901 | 8mer-1a | 75937894 | 75937913 | 152 | -28.16 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000188878.19 | ENST00000586631.2 | FBF1-204 | hsa-miR-337-3p | chr17 | 75937741 | 75937748 | 8mer-1a | 75937741 | 75937762 | 140 | -8.13 |
| ADediting_496066 | chr15_66496985_- | ENSG00000188878.19 | ENST00000319129.10 | FBF1-201 | hsa-miR-4512 | chr17 | 75910166 | 75910172 | 7mer-m8 | 75910165 | 75910186 | 149 | -19.33 |
| ADediting_496066 | chr15_66496985_- | ENSG00000188878.19 | ENST00000586717.5 | FBF1-205 | hsa-miR-4512 | chr17 | 75910166 | 75910172 | 7mer-m8 | 75910165 | 75910186 | 149 | -19.33 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for FBF1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000586717.5 | protein_coding |  |  |
| ENST00000319129.10 | protein_coding |  |  |
| ENST00000592193.6 | protein_coding |  |  |
| ENST00000636174.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_664659 | ENST00000586717.5 | chr17_75920350_- | 1986 | -2139.40 | -2136.00 | -2139.40 |
| ADediting_664659 | ENST00000319129.10 | chr17_75920350_- | 1584 | -1858.00 | -1854.60 | -1858.00 |
| ADediting_664659 | ENST00000592193.6 | chr17_75920350_- | 1751 | -1491.20 | -1487.80 | -1491.20 |
| ADediting_664659 | ENST00000636174.1 | chr17_75920350_- | 1933 | -1579.30 | -1575.90 | -1579.30 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for FBF1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_664638 | chr17_75912892_- | 0.0065760647805015 | 0.154048289415275 | 0.621852122465082 | 0.0281214805100241 | 6.10975948361443e-21 | 0.499195206001965 |
| DLPFC | ADediting_664641 | chr17_75912928_- | 0.0309505442725575 | 0.122582251229161 | 0.932567712609409 | 0.00482525689266332 | 1.6798774207528e-17 | 0.458262368495973 |
| DLPFC | ADediting_664643 | chr17_75912932_- | 0.0117190851373678 | 0.142995594989932 | 0.937791763406685 | 0.00445065101510989 | 9.20487955741809e-19 | 0.473918036202552 |
| DLPFC | ADediting_664644 | chr17_75912945_- | 0.358769293229931 | 0.0522981731951235 | 0.843816662809747 | -0.0112346696247483 | 8.65646283763131e-09 | 0.319551619536115 |
| DLPFC | ADediting_664739 | chr17_75938316_- | 0.223975668288945 | 0.0692623719836108 | 0.346534247010708 | -0.0536423193054105 | 5.39330375495972e-13 | 0.394628129555062 |
| DLPFC | ADediting_664740 | chr17_75938344_- | 0.00967854780420377 | 0.146734417112137 | 0.384735022892217 | 0.0495373283851029 | 1.21394126726129e-09 | 0.336471076267146 |
| DLPFC | ADediting_664747 | chr17_75938437_- | 0.0176533801248412 | 0.13469594662694 | 0.613065343509425 | 0.0288324897605219 | 2.66380574966789e-12 | 0.383512279426019 |
| DLPFC | ADediting_664749 | chr17_75938472_- | 0.00186533198370885 | 0.176015503436977 | 0.0850614250123439 | 0.0979659326418227 | 1.41638515045512e-09 | 0.335179405053178 |
| DLPFC | ADediting_664750 | chr17_75938473_- | 0.0201316330866695 | 0.131943299269054 | 0.270993519898906 | 0.0627117432264012 | 1.60944862113608e-09 | 0.334104710296288 |
| DLPFC | ADediting_664763 | chr17_75939179_- | 0.111156377823296 | 0.090657119031125 | 0.836419310295765 | 0.0117741925857271 | 5.97122160188132e-14 | 0.409293234487197 |
| DLPFC | ADediting_664764 | chr17_75939184_- | 0.0982902369554594 | 0.0940671332021314 | 0.745142236016502 | 0.0185349646756475 | 1.53460546338232e-11 | 0.370821543736599 |
| DLPFC | ADediting_664765 | chr17_75939209_- | 0.0326327098880869 | 0.121390501880574 | 0.266535920004256 | 0.063297245620055 | 3.83997014155237e-10 | 0.345926813798144 |
| TCX | ADediting_664772 | chr17_75939976_- | 0.510969427261496 | 0.0540838187489672 | 0.207928159772243 | -0.10340919606218 | 1.36825916556058e-05 | 0.34689765893587 |
| TCX | ADediting_664775 | chr17_75940006_- | 0.974883861199932 | 0.00259230780348638 | 0.149521451872669 | -0.118251367559293 | 9.41235221630965e-06 | 0.352968801387807 |
| TCX | ADediting_664776 | chr17_75940013_- | 0.763727042084806 | 0.0247463383720826 | 0.101400038959257 | -0.134267482495196 | 1.01677444520153e-07 | 0.418097471313772 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.55601241417997e-12 | 0.38730092834718 | 2.24660167101289e-17 | 0.456650130799337 | 1.0888096077136e-27 | 0.566320556956308 |
| AC | 2.11805181328737e-19 | 0.528644948707915 | 1.12148697262065e-13 | 0.446893411242315 | 1.2683972207415e-32 | 0.659810691242549 |
| PCC | 0.000332750594537919 | 0.256958697536514 | 0.00193609149262698 | 0.222932132083287 | 1.94893756446875e-17 | 0.564060568883987 |
| TCX | 0.031478312236604 | 0.175727248295771 | 0.0383410799682219 | -0.16930539846343 | 3.88190761473405e-22 | 0.685376621253785 |
| FP | 4.64483741610488e-08 | 0.395534076591582 | 0.00205475611884107 | 0.229545211594748 | 1.23166122790109e-15 | 0.552839796280526 |
| IFG | 0.000118034177417383 | 0.694298854482032 | 7.36305885179719e-07 | 0.8141600609166 | 0.013042074731991 | 0.489343458159021 |
| PG | 0.724144477353704 | -0.0260489468287824 | 0.298810042140455 | 0.076586680413043 | 3.49124092510678e-09 | 0.41610061280171 |
| STG | 0.000212853820394512 | 0.393522751543719 | 0.0492403020395766 | 0.215266138475413 | 2.62665248361616e-07 | 0.526874593012415 |
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Relation with AD stages for FBF1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 1.19714149094614e-08 | 0.519034206086692 |
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RelatedDrugs for FBF1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for FBF1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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