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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for CNDP1 |
 Gene summary |
| Gene information | Gene symbol | CNDP1 | Gene ID | 84735 |
| Gene name | carnosine dipeptidase 1 | |
| Synonyms | CN1|CPGL2|HsT2308 | |
| Cytomap | 18q22.3 | |
| Type of gene | protein-coding | |
| Description | beta-Ala-His dipeptidaseCNDP dipeptidase 1carnosinase 1carnosine dipeptidase 1 (metallopeptidase M20 family)glutamate carboxypeptidase-like protein 2serum carnosinase | |
| Modification date | 20200313 | |
| UniProtAcc | Q96KN2, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| CNDP1 | GO:0006508 | proteolysis | 24891507 |
| CNDP1 | GO:0032268 | regulation of cellular protein metabolic process | 24891507 |
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RNA A-to-I events for CNDP1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_698084(74542781, +), ADediting_698085(74543853, +), ADediting_698086(74560073, +), ADediting_698087(74560074, +), ADediting_698088(74560079, +), ADediting_698089(74560133, +), ADediting_698090(74560145, +), ADediting_698091(74560173, +), ADediting_698092(74560218, +), ADediting_698093(74560466, +), ADediting_698094(74560522, +), ADediting_698095(74560528, +), ADediting_698096(74560533, +), ADediting_698097(74560558, +), ADediting_698098(74560584, +), ADediting_698099(74560623, +), ADediting_698100(74561160, +), ADediting_698101(74561205, +), ADediting_698102(74561277, +), ADediting_698103(74561295, +), ADediting_698104(74561296, +), ADediting_698105(74561305, +), ADediting_698106(74561317, +), ADediting_698107(74561358, +), ADediting_698108(74561368, +), ADediting_698109(74572549, +), ADediting_698110(74572554, +), ADediting_698111(74572555, +), ADediting_698112(74572568, +), ADediting_698113(74572601, +), ADediting_698114(74572602, +), ADediting_698115(74572604, +), ADediting_698116(74572611, +), ADediting_698117(74572612, +), ADediting_698118(74572625, +), ADediting_698119(74572626, +), ADediting_698120(74572628, +), ADediting_698121(74572629, +), ADediting_698122(74572630, +), ADediting_698123(74572632, +), ADediting_698124(74572634, +), ADediting_698125(74572635, +), ADediting_698126(74572636, +), ADediting_698127(74572637, +), ADediting_698128(74572641, +), ADediting_698129(74572645, +), ADediting_698130(74572652, +), ADediting_698131(74572667, +), ADediting_698132(74572681, +), ADediting_698133(74572682, +), ADediting_698134(74572694, +), ADediting_698135(74572708, +), ADediting_698136(74572716, +), ADediting_698137(74572720, +), ADediting_698138(74575139, +), ADediting_698139(74575144, +), ADediting_698140(74575163, +), ADediting_698141(74575923, +), ADediting_698142(74575950, +), ADediting_698143(74575970, +), ADediting_698144(74576045, +), ADediting_698145(74576051, +), ADediting_698146(74576054, +), ADediting_698147(74576076, +), ADediting_698148(74576251, +), ADediting_698149(74576277, +), ADediting_698150(74576304, +), ADediting_698151(74576339, +), ADediting_698152(74576348, +), ADediting_698153(74576350, +), ADediting_698154(74576354, +), ADediting_698155(74576400, +), ADediting_698156(74580704, +), ADediting_698157(74580705, +), ADediting_698158(74580710, +), ADediting_698159(74580766, +), ADediting_698160(74585737, +), ADediting_698161(74585873, +), ADediting_698162(74585919, +), ADediting_1551207(74560446, +), ADediting_1551208(74578546, +), ADediting_1551209(74583283, +), ADediting_1630533(74560594, +), ADediting_1630534(74585808, +), ADediting_1630535(74585809, +), |
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RNA editing positional annotations for CNDP1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_698084 | chr18_74542781_+ | intronic |
| ADediting_698085 | chr18_74543853_+ | intronic |
| ADediting_698086 | chr18_74560073_+ | intronic |
| ADediting_698087 | chr18_74560074_+ | intronic |
| ADediting_698088 | chr18_74560079_+ | intronic |
| ADediting_698089 | chr18_74560133_+ | intronic |
| ADediting_698090 | chr18_74560145_+ | intronic |
| ADediting_698091 | chr18_74560173_+ | intronic |
| ADediting_698092 | chr18_74560218_+ | intronic |
| ADediting_698093 | chr18_74560466_+ | intronic |
| ADediting_698094 | chr18_74560522_+ | intronic |
| ADediting_698095 | chr18_74560528_+ | intronic |
| ADediting_698096 | chr18_74560533_+ | intronic |
| ADediting_698097 | chr18_74560558_+ | intronic |
| ADediting_698098 | chr18_74560584_+ | intronic |
| ADediting_698099 | chr18_74560623_+ | intronic |
| ADediting_698100 | chr18_74561160_+ | intronic |
| ADediting_698101 | chr18_74561205_+ | intronic |
| ADediting_698102 | chr18_74561277_+ | intronic |
| ADediting_698103 | chr18_74561295_+ | intronic |
| ADediting_698104 | chr18_74561296_+ | intronic |
| ADediting_698105 | chr18_74561305_+ | intronic |
| ADediting_698106 | chr18_74561317_+ | intronic |
| ADediting_698107 | chr18_74561358_+ | intronic |
| ADediting_698108 | chr18_74561368_+ | intronic |
| ADediting_698109 | chr18_74572549_+ | intronic |
| ADediting_698110 | chr18_74572554_+ | intronic |
| ADediting_698111 | chr18_74572555_+ | intronic |
| ADediting_698112 | chr18_74572568_+ | intronic |
| ADediting_698113 | chr18_74572601_+ | intronic |
| ADediting_698114 | chr18_74572602_+ | intronic |
| ADediting_698115 | chr18_74572604_+ | intronic |
| ADediting_698116 | chr18_74572611_+ | intronic |
| ADediting_698117 | chr18_74572612_+ | intronic |
| ADediting_698118 | chr18_74572625_+ | intronic |
| ADediting_698119 | chr18_74572626_+ | intronic |
| ADediting_698120 | chr18_74572628_+ | intronic |
| ADediting_698121 | chr18_74572629_+ | intronic |
| ADediting_698122 | chr18_74572630_+ | intronic |
| ADediting_698123 | chr18_74572632_+ | intronic |
| ADediting_698124 | chr18_74572634_+ | intronic |
| ADediting_698125 | chr18_74572635_+ | intronic |
| ADediting_698126 | chr18_74572636_+ | intronic |
| ADediting_698127 | chr18_74572637_+ | intronic |
| ADediting_698128 | chr18_74572641_+ | intronic |
| ADediting_698129 | chr18_74572645_+ | intronic |
| ADediting_698130 | chr18_74572652_+ | intronic |
| ADediting_698131 | chr18_74572667_+ | intronic |
| ADediting_698132 | chr18_74572681_+ | intronic |
| ADediting_698133 | chr18_74572682_+ | intronic |
| ADediting_698134 | chr18_74572694_+ | intronic |
| ADediting_698135 | chr18_74572708_+ | intronic |
| ADediting_698136 | chr18_74572716_+ | intronic |
| ADediting_698137 | chr18_74572720_+ | intronic |
| ADediting_698138 | chr18_74575139_+ | intronic |
| ADediting_698139 | chr18_74575144_+ | intronic |
| ADediting_698140 | chr18_74575163_+ | intronic |
| ADediting_698141 | chr18_74575923_+ | intronic |
| ADediting_698142 | chr18_74575950_+ | intronic |
| ADediting_698143 | chr18_74575970_+ | intronic |
| ADediting_698144 | chr18_74576045_+ | intronic |
| ADediting_698145 | chr18_74576051_+ | intronic |
| ADediting_698146 | chr18_74576054_+ | intronic |
| ADediting_698147 | chr18_74576076_+ | intronic |
| ADediting_698148 | chr18_74576251_+ | intronic |
| ADediting_698149 | chr18_74576277_+ | intronic |
| ADediting_698150 | chr18_74576304_+ | intronic |
| ADediting_698151 | chr18_74576339_+ | intronic |
| ADediting_698152 | chr18_74576348_+ | intronic |
| ADediting_698153 | chr18_74576350_+ | intronic |
| ADediting_698154 | chr18_74576354_+ | intronic |
| ADediting_698155 | chr18_74576400_+ | intronic |
| ADediting_698156 | chr18_74580704_+ | intronic |
| ADediting_698157 | chr18_74580705_+ | intronic |
| ADediting_698158 | chr18_74580710_+ | intronic |
| ADediting_698159 | chr18_74580766_+ | intronic |
| ADediting_698160 | chr18_74585737_+ | UTR3 |
| ADediting_698161 | chr18_74585873_+ | UTR3 |
| ADediting_698162 | chr18_74585919_+ | UTR3 |
| ADediting_1551207 | chr18_74560446_+ | intronic |
| ADediting_1551208 | chr18_74578546_+ | intronic |
| ADediting_1551209 | chr18_74583283_+ | intronic |
| ADediting_1630533 | chr18_74560594_+ | intronic |
| ADediting_1630534 | chr18_74585808_+ | UTR3 |
| ADediting_1630535 | chr18_74585809_+ | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_698084 | chr18_74542781_+ | SINE | Alu | Name=AluJb |
| ADediting_698085 | chr18_74543853_+ | SINE | Alu | Name=AluJo |
| ADediting_698086 | chr18_74560073_+ | SINE | Alu | Name=AluSg |
| ADediting_698087 | chr18_74560074_+ | SINE | Alu | Name=AluSg |
| ADediting_698088 | chr18_74560079_+ | SINE | Alu | Name=AluSg |
| ADediting_698089 | chr18_74560133_+ | SINE | Alu | Name=AluSg |
| ADediting_698090 | chr18_74560145_+ | SINE | Alu | Name=AluSg |
| ADediting_698091 | chr18_74560173_+ | SINE | Alu | Name=AluSg |
| ADediting_698092 | chr18_74560218_+ | SINE | Alu | Name=AluSg |
| ADediting_698093 | chr18_74560466_+ | SINE | Alu | Name=AluJb |
| ADediting_698094 | chr18_74560522_+ | SINE | Alu | Name=AluJb |
| ADediting_698095 | chr18_74560528_+ | SINE | Alu | Name=AluJb |
| ADediting_698096 | chr18_74560533_+ | SINE | Alu | Name=AluJb |
| ADediting_698097 | chr18_74560558_+ | SINE | Alu | Name=AluJb |
| ADediting_698098 | chr18_74560584_+ | SINE | Alu | Name=AluJb |
| ADediting_698099 | chr18_74560623_+ | SINE | Alu | Name=AluJb |
| ADediting_698100 | chr18_74561160_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698101 | chr18_74561205_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698102 | chr18_74561277_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698103 | chr18_74561295_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698104 | chr18_74561296_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698105 | chr18_74561305_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698106 | chr18_74561317_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698107 | chr18_74561358_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698108 | chr18_74561368_+ | SINE | Alu | Name=AluSx1 |
| ADediting_698109 | chr18_74572549_+ | SINE | Alu | Name=AluJb |
| ADediting_698110 | chr18_74572554_+ | SINE | Alu | Name=AluJb |
| ADediting_698111 | chr18_74572555_+ | SINE | Alu | Name=AluJb |
| ADediting_698112 | chr18_74572568_+ | SINE | Alu | Name=AluJb |
| ADediting_698113 | chr18_74572601_+ | SINE | Alu | Name=AluJb |
| ADediting_698114 | chr18_74572602_+ | SINE | Alu | Name=AluJb |
| ADediting_698115 | chr18_74572604_+ | SINE | Alu | Name=AluJb |
| ADediting_698116 | chr18_74572611_+ | SINE | Alu | Name=AluJb |
| ADediting_698117 | chr18_74572612_+ | SINE | Alu | Name=AluJb |
| ADediting_698118 | chr18_74572625_+ | SINE | Alu | Name=AluJb |
| ADediting_698119 | chr18_74572626_+ | SINE | Alu | Name=AluJb |
| ADediting_698120 | chr18_74572628_+ | SINE | Alu | Name=AluJb |
| ADediting_698121 | chr18_74572629_+ | SINE | Alu | Name=AluJb |
| ADediting_698122 | chr18_74572630_+ | SINE | Alu | Name=AluJb |
| ADediting_698123 | chr18_74572632_+ | SINE | Alu | Name=AluJb |
| ADediting_698124 | chr18_74572634_+ | SINE | Alu | Name=AluJb |
| ADediting_698125 | chr18_74572635_+ | SINE | Alu | Name=AluJb |
| ADediting_698126 | chr18_74572636_+ | SINE | Alu | Name=AluJb |
| ADediting_698127 | chr18_74572637_+ | SINE | Alu | Name=AluJb |
| ADediting_698128 | chr18_74572641_+ | SINE | Alu | Name=AluJb |
| ADediting_698129 | chr18_74572645_+ | SINE | Alu | Name=AluJb |
| ADediting_698130 | chr18_74572652_+ | SINE | Alu | Name=AluJb |
| ADediting_698131 | chr18_74572667_+ | SINE | Alu | Name=AluJb |
| ADediting_698132 | chr18_74572681_+ | SINE | Alu | Name=AluJb |
| ADediting_698133 | chr18_74572682_+ | SINE | Alu | Name=AluJb |
| ADediting_698134 | chr18_74572694_+ | SINE | Alu | Name=AluJb |
| ADediting_698135 | chr18_74572708_+ | SINE | Alu | Name=AluJb |
| ADediting_698136 | chr18_74572716_+ | SINE | Alu | Name=AluJb |
| ADediting_698137 | chr18_74572720_+ | SINE | Alu | Name=AluJb |
| ADediting_698138 | chr18_74575139_+ | Low_complexity | Low_complexity | Name=GA-rich |
| ADediting_698139 | chr18_74575144_+ | Low_complexity | Low_complexity | Name=GA-rich |
| ADediting_698140 | chr18_74575163_+ | Low_complexity | Low_complexity | Name=GA-rich |
| ADediting_698141 | chr18_74575923_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698142 | chr18_74575950_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698143 | chr18_74575970_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698144 | chr18_74576045_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698145 | chr18_74576051_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698146 | chr18_74576054_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698147 | chr18_74576076_+ | SINE | Alu | Name=AluSc8 |
| ADediting_698148 | chr18_74576251_+ | SINE | Alu | Name=AluJo |
| ADediting_698149 | chr18_74576277_+ | SINE | Alu | Name=AluJo |
| ADediting_698150 | chr18_74576304_+ | SINE | Alu | Name=AluJo |
| ADediting_698151 | chr18_74576339_+ | SINE | Alu | Name=AluJo |
| ADediting_698152 | chr18_74576348_+ | SINE | Alu | Name=AluJo |
| ADediting_698153 | chr18_74576350_+ | SINE | Alu | Name=AluJo |
| ADediting_698154 | chr18_74576354_+ | SINE | Alu | Name=AluJo |
| ADediting_698155 | chr18_74576400_+ | SINE | Alu | Name=AluJo |
| ADediting_698156 | chr18_74580704_+ | SINE | Alu | Name=AluJo |
| ADediting_698157 | chr18_74580705_+ | SINE | Alu | Name=AluJo |
| ADediting_698158 | chr18_74580710_+ | SINE | Alu | Name=AluJo |
| ADediting_698159 | chr18_74580766_+ | SINE | Alu | Name=AluJo |
| ADediting_698160 | chr18_74585737_+ | SINE | Alu | Name=AluSx |
| ADediting_698161 | chr18_74585873_+ | SINE | Alu | Name=AluSx |
| ADediting_698162 | chr18_74585919_+ | SINE | Alu | Name=AluSx |
| ADediting_1551207 | chr18_74560446_+ | SINE | Alu | Name=AluJb |
| ADediting_1551208 | chr18_74578546_+ | SINE | Alu | Name=FRAM |
| ADediting_1551209 | chr18_74583283_+ | SINE | Alu | Name=AluSz |
| ADediting_1630533 | chr18_74560594_+ | SINE | Alu | Name=AluJb |
| ADediting_1630534 | chr18_74585808_+ | SINE | Alu | Name=AluSx |
| ADediting_1630535 | chr18_74585809_+ | SINE | Alu | Name=AluSx |
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RNA A-to-I editing events in the alternative splicing sites for CNDP1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CNDP1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for CNDP1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for CNDP1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1630534 | chr18_74585808_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-3157-5p | chr18 | 74585802 | 74585808 | 7mer-m8 | 74585788 | 74585809 | 163 | -22.12 |
| ADediting_1630534 | chr18_74585808_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-3157-5p | chr18 | 74585802 | 74585808 | 7mer-m8 | 74585788 | 74585809 | 163 | -22.12 |
| ADediting_1630535 | chr18_74585809_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-3146 | chr18 | 74585805 | 74585811 | 7mer-m8 | 74585791 | 74585812 | 140 | -16.01 |
| ADediting_1630535 | chr18_74585809_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-3146 | chr18 | 74585805 | 74585811 | 7mer-m8 | 74585791 | 74585812 | 140 | -16.01 |
| ADediting_698161 | chr18_74585873_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-140-3p | chr18 | 74585868 | 74585874 | 7mer-m8 | 74585855 | 74585875 | 163 | -23.48 |
| ADediting_698161 | chr18_74585873_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-140-3p | chr18 | 74585868 | 74585874 | 7mer-m8 | 74585855 | 74585875 | 163 | -23.48 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1630535 | chr18_74585809_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-4716-5p | chr18 | 74585807 | 74585813 | 7mer-m8 | 74585793 | 74585814 | 140 | -12.17 |
| ADediting_1630535 | chr18_74585809_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-4716-5p | chr18 | 74585807 | 74585813 | 7mer-m8 | 74585793 | 74585814 | 140 | -12.17 |
| ADediting_698161 | chr18_74585873_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-7151-3p | chr18 | 74585866 | 74585872 | 7mer-m8 | 74585852 | 74585873 | 143 | -18.12 |
| ADediting_698161 | chr18_74585873_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-8052 | chr18 | 74585872 | 74585878 | 7mer-1a | 74585860 | 74585878 | 143 | -23.66 |
| ADediting_698161 | chr18_74585873_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-7151-3p | chr18 | 74585866 | 74585872 | 7mer-m8 | 74585852 | 74585873 | 143 | -18.12 |
| ADediting_698161 | chr18_74585873_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-8052 | chr18 | 74585872 | 74585878 | 7mer-1a | 74585860 | 74585878 | 143 | -23.66 |
| ADediting_698162 | chr18_74585919_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-1343-3p | chr18 | 74585915 | 74585921 | 7mer-m8 | 74585899 | 74585922 | 150 | -24.17 |
| ADediting_698162 | chr18_74585919_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-6742-3p | chr18 | 74585914 | 74585921 | 8mer-1a | 74585902 | 74585921 | 145 | -14.93 |
| ADediting_698162 | chr18_74585919_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-6783-3p | chr18 | 74585915 | 74585921 | 7mer-m8 | 74585902 | 74585922 | 146 | -17.13 |
| ADediting_698162 | chr18_74585919_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-1343-3p | chr18 | 74585915 | 74585921 | 7mer-m8 | 74585899 | 74585922 | 150 | -24.17 |
| ADediting_698162 | chr18_74585919_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-6742-3p | chr18 | 74585914 | 74585921 | 8mer-1a | 74585902 | 74585921 | 145 | -14.93 |
| ADediting_698162 | chr18_74585919_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-6783-3p | chr18 | 74585915 | 74585921 | 7mer-m8 | 74585902 | 74585922 | 146 | -17.13 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6765-5p | chr18 | 74576276 | 74576282 | 7mer-m8 | 74576262 | 74576283 | 153 | -25.69 |
| ADediting_698150 | chr18_74576304_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-4746-5p | chr18 | 74576298 | 74576304 | 7mer-m8 | 74576283 | 74576305 | 150 | -21.67 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-340-3p | chr18 | 74576349 | 74576355 | 7mer-m8 | 74576335 | 74576356 | 141 | -15.89 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6827-3p | chr18 | 74576349 | 74576355 | 7mer-m8 | 74576336 | 74576356 | 147 | -16.55 |
| ADediting_698155 | chr18_74576400_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-1199-5p | chr18 | 74576394 | 74576400 | 7mer-m8 | 74576382 | 74576401 | 156 | -29.7 |
| ADediting_698155 | chr18_74576400_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6078 | chr18 | 74576397 | 74576404 | 8mer-1a | 74576385 | 74576404 | 152 | -20.71 |
| ADediting_698155 | chr18_74576400_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6751-3p | chr18 | 74576394 | 74576400 | 7mer-m8 | 74576381 | 74576401 | 141 | -18.35 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-1233-5p | chr18 | 74576272 | 74576278 | 7mer-m8 | 74576255 | 74576279 | 146 | -24.89 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-1273h-5p | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576257 | 74576278 | 149 | -19.5 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-30b-3p | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576256 | 74576278 | 146 | -14.96 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-3689a-3p | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576254 | 74576278 | 146 | -21.87 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-3689b-3p | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576260 | 74576278 | 145 | -16.39 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-3689c | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576260 | 74576278 | 145 | -16.39 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6778-5p | chr18 | 74576272 | 74576278 | 7mer-m8 | 74576257 | 74576279 | 151 | -22.69 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6779-5p | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576257 | 74576278 | 149 | -18.63 |
| ADediting_698149 | chr18_74576277_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6780a-5p | chr18 | 74576271 | 74576277 | 7mer-m8 | 74576256 | 74576278 | 141 | -15.64 |
| ADediting_698150 | chr18_74576304_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6811-3p | chr18 | 74576303 | 74576310 | 8mer-1a | 74576293 | 74576310 | 155 | -24.26 |
| ADediting_698152 | chr18_74576348_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-1283 | chr18 | 74576343 | 74576350 | 8mer-1a | 74576329 | 74576350 | 149 | -11.59 |
| ADediting_698152 | chr18_74576348_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-4684-5p | chr18 | 74576346 | 74576352 | 7mer-m8 | 74576331 | 74576353 | 151 | -11.5 |
| ADediting_698152 | chr18_74576348_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-519a-2-5p | chr18 | 74576345 | 74576352 | 8mer-1a | 74576332 | 74576352 | 153 | -15.12 |
| ADediting_698152 | chr18_74576348_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-520b-5p | chr18 | 74576345 | 74576352 | 8mer-1a | 74576332 | 74576352 | 153 | -15.12 |
| ADediting_698153 | chr18_74576350_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-4684-5p | chr18 | 74576346 | 74576352 | 7mer-m8 | 74576331 | 74576353 | 151 | -11.5 |
| ADediting_698153 | chr18_74576350_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-519a-2-5p | chr18 | 74576345 | 74576352 | 8mer-1a | 74576332 | 74576352 | 153 | -15.12 |
| ADediting_698153 | chr18_74576350_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-520b-5p | chr18 | 74576345 | 74576352 | 8mer-1a | 74576332 | 74576352 | 153 | -15.12 |
| ADediting_698153 | chr18_74576350_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6818-3p | chr18 | 74576348 | 74576354 | 7mer-m8 | 74576334 | 74576355 | 140 | -12.56 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-10a-5p | chr18 | 74576352 | 74576358 | 7mer-m8 | 74576337 | 74576359 | 149 | -14.2 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-10b-5p | chr18 | 74576352 | 74576358 | 7mer-m8 | 74576337 | 74576359 | 141 | -14.2 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-4725-5p | chr18 | 74576353 | 74576359 | 7mer-m8 | 74576340 | 74576360 | 140 | -15.96 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-504-5p | chr18 | 74576353 | 74576359 | 7mer-m8 | 74576338 | 74576360 | 154 | -22.93 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-5699-3p | chr18 | 74576350 | 74576356 | 7mer-m8 | 74576336 | 74576357 | 148 | -16.39 |
| ADediting_698154 | chr18_74576354_+ | ENSG00000150656.15 | ENST00000578498.1 | CNDP1-202 | hsa-miR-6818-3p | chr18 | 74576348 | 74576354 | 7mer-m8 | 74576334 | 74576355 | 140 | -12.56 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-4477b | chr18 | 74584774 | 74584780 | 7mer-m8 | 74584760 | 74584781 | 153 | -13.89 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-4477b | chr18 | 74584915 | 74584921 | 7mer-m8 | 74584901 | 74584922 | 147 | -13.43 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-4477b | chr18 | 74584774 | 74584780 | 7mer-m8 | 74584760 | 74584781 | 153 | -13.89 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-4477b | chr18 | 74584915 | 74584921 | 7mer-m8 | 74584901 | 74584922 | 147 | -13.43 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-4775 | chr18 | 74585605 | 74585612 | 8mer-1a | 74585588 | 74585612 | 154 | -12.75 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-4775 | chr18 | 74585605 | 74585612 | 8mer-1a | 74585588 | 74585612 | 154 | -12.75 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-5585-3p | chr18 | 74586852 | 74586858 | 7mer-m8 | 74586838 | 74586859 | 150 | -18.46 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-5585-3p | chr18 | 74586852 | 74586858 | 7mer-m8 | 74586838 | 74586859 | 150 | -18.46 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1556067 | chr19_40282625_- | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-641 | chr18 | 74584690 | 74584696 | 7mer-m8 | 74584672 | 74584697 | 144 | -9.28 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-641 | chr18 | 74584690 | 74584696 | 7mer-m8 | 74584672 | 74584697 | 144 | -9.28 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000150656.15 | ENST00000358821.8 | CNDP1-201 | hsa-miR-641 | chr18 | 74584690 | 74584696 | 7mer-m8 | 74584672 | 74584697 | 144 | -9.28 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000150656.15 | ENST00000582365.1 | CNDP1-203 | hsa-miR-641 | chr18 | 74584690 | 74584696 | 7mer-m8 | 74584672 | 74584697 | 144 | -9.28 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for CNDP1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000358821.8 | protein_coding |  |  |
| ENST00000582365.1 | protein_coding |  |  |
| ENST00000578498.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_698160 | ENST00000358821.8 | chr18_74585737_+ | 2867 | -1277.10 | -1278.50 | -1278.90 |
| ADediting_1630534 | ENST00000358821.8 | chr18_74585808_+ | 2938 | -1281.90 | -1278.50 | -1278.90 |
| ADediting_1630535 | ENST00000358821.8 | chr18_74585809_+ | 2939 | -1278.50 | -1278.50 | -1278.90 |
| ADediting_698161 | ENST00000358821.8 | chr18_74585873_+ | 3003 | -1278.20 | -1278.50 | -1278.90 |
| ADediting_698162 | ENST00000358821.8 | chr18_74585919_+ | 3049 | -1277.90 | -1278.50 | -1278.90 |
| ADediting_698160 | ENST00000582365.1 | chr18_74585737_+ | 2636 | -1191.00 | -1192.40 | -1192.80 |
| ADediting_1630534 | ENST00000582365.1 | chr18_74585808_+ | 2707 | -1195.80 | -1192.40 | -1192.80 |
| ADediting_1630535 | ENST00000582365.1 | chr18_74585809_+ | 2708 | -1192.40 | -1192.40 | -1192.80 |
| ADediting_698161 | ENST00000582365.1 | chr18_74585873_+ | 2772 | -1192.10 | -1192.40 | -1192.80 |
| ADediting_698162 | ENST00000582365.1 | chr18_74585919_+ | 2818 | -1192.30 | -1192.40 | -1192.80 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_698148 | ENST00000578498.1 | chr18_74576251_+ | 159 | -138.10 | -137.90 | -147.80 |
| ADediting_698149 | ENST00000578498.1 | chr18_74576277_+ | 185 | -141.20 | -137.90 | -147.80 |
| ADediting_698150 | ENST00000578498.1 | chr18_74576304_+ | 212 | -140.40 | -137.90 | -147.80 |
| ADediting_698151 | ENST00000578498.1 | chr18_74576339_+ | 247 | -140.60 | -137.90 | -147.80 |
| ADediting_698152 | ENST00000578498.1 | chr18_74576348_+ | 256 | -140.00 | -137.90 | -147.80 |
| ADediting_698153 | ENST00000578498.1 | chr18_74576350_+ | 258 | -141.50 | -137.90 | -147.80 |
| ADediting_698154 | ENST00000578498.1 | chr18_74576354_+ | 262 | -139.00 | -137.90 | -147.80 |
| ADediting_698155 | ENST00000578498.1 | chr18_74576400_+ | 308 | -141.80 | -137.90 | -147.80 |
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Relation with ADAR for CNDP1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_698106 | chr18_74561317_+ | 0.242194604488546 | 0.0666195247801014 | 0.691466464112524 | -0.0226289887155287 | 2.64533906351118e-16 | 0.442619200833393 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 8.41172327847744e-14 | 0.407056640227785 | 5.40591903298638e-09 | 0.323702332063094 | 1.26872331411408e-09 | 0.336102038680307 |
| AC | 7.60223615988024e-32 | 0.653589954327597 | 8.21467283668457e-25 | 0.589735930168446 | 3.11434863800562e-16 | 0.486123669478367 |
| TCX | 0.00148150178899043 | 0.257275287777954 | 0.0670254569155125 | -0.149949357330192 | 5.96656629913484e-10 | 0.478372480556302 |
| FP | 0.00236058475167018 | 0.226532955934117 | 3.13078209583341e-06 | 0.341290241268265 | 0.00539829947498995 | 0.207722515275899 |
| PG | 3.245074844671e-18 | 0.581486720829581 | 2.29799044805983e-06 | 0.338474367791573 | 0.0100269277709328 | 0.188377300897246 |
| STG | 4.83239079467318e-07 | 0.516811025782849 | 0.00056848505959152 | 0.368227245892284 | 0.172774252687492 | 0.150158017237246 |
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Relation with AD stages for CNDP1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for CNDP1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CNDP1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| CNDP1 | C0011881 | Diabetic Nephropathy | 3 | CTD_human |
| CNDP1 | C0017667 | Nodular glomerulosclerosis | 3 | CTD_human |
| CNDP1 | C0020796 | Profound Mental Retardation | 2 | CTD_human |
| CNDP1 | C0025363 | Mental Retardation, Psychosocial | 2 | CTD_human |
| CNDP1 | C0917816 | Mental deficiency | 2 | CTD_human |
| CNDP1 | C3714756 | Intellectual Disability | 2 | CTD_human |
| CNDP1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| CNDP1 | C0027854 | Neurologic Manifestations | 1 | CTD_human |
| CNDP1 | C0235031 | Neurologic Symptoms | 1 | CTD_human |
| CNDP1 | C0268632 | Homocarnosinosis | 1 | CTD_human |
| CNDP1 | C0422837 | Neurological observations | 1 | CTD_human |
| CNDP1 | C0521654 | Neurologic Deficits | 1 | CTD_human |
| CNDP1 | C0746857 | Focal Neurologic Deficits | 1 | CTD_human |
| CNDP1 | C0751377 | Neurologic Dysfunction | 1 | CTD_human |
| CNDP1 | C0751378 | Neurologic Signs | 1 | CTD_human |
| CNDP1 | C3495554 | Homocarnosinase deficiency | 1 | CTD_human |
| CNDP1 | C3495555 | Carnosinemia | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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