ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for COG8

Gene summary

Gene information	Gene symbol	COG8
	Gene ID	84342
	Gene name	component of oligomeric golgi complex 8
	Synonyms	CDG2H\|DOR1
	Cytomap	16q22.1
	Type of gene	protein-coding
	Description	conserved oligomeric Golgi complex subunit 8COG complex subunit 8conserved oligomeric golgi complex component 8dependent on RIC1
	Modification date	20200328
	UniProtAcc	Q96MW5,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

Top

RNA A-to-I events for COG8

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_560938(69327161, -), ADediting_560939(69327197, -), ADediting_560940(69327203, -), ADediting_560941(69327233, -), ADediting_560942(69327235, -), ADediting_560943(69327244, -), ADediting_560944(69327253, -), ADediting_560945(69327257, -), ADediting_560946(69327264, -), ADediting_560947(69327265, -), ADediting_560948(69327266, -), ADediting_560949(69327273, -), ADediting_560950(69327296, -), ADediting_560951(69327300, -), ADediting_560952(69327302, -), ADediting_560953(69327305, -), ADediting_560954(69327306, -), ADediting_560955(69327316, -), ADediting_560956(69327332, -), ADediting_560957(69327335, -), ADediting_560958(69327336, -), ADediting_560959(69327341, -), ADediting_560960(69327343, -), ADediting_560961(69327344, -), ADediting_560962(69327345, -), ADediting_560963(69327346, -), ADediting_560964(69327347, -), ADediting_560965(69327350, -), ADediting_560966(69327361, -), ADediting_560967(69327369, -), ADediting_560968(69327371, -), ADediting_560969(69327372, -), ADediting_560970(69327386, -), ADediting_560971(69327387, -), ADediting_560972(69327392, -), ADediting_560973(69327395, -), ADediting_560974(69327400, -), ADediting_560975(69327405, -), ADediting_560976(69327410, -), ADediting_560977(69327414, -), ADediting_560978(69327418, -), ADediting_560979(69327419, -), ADediting_560980(69327435, -), ADediting_560981(69327440, -), ADediting_560982(69327441, -), ADediting_560983(69327463, -), ADediting_560984(69327755, -), ADediting_560985(69327767, -), ADediting_560986(69327768, -), ADediting_560987(69327790, -), ADediting_560988(69327791, -), ADediting_560989(69327795, -), ADediting_560990(69327809, -), ADediting_560991(69327820, -), ADediting_560992(69327832, -), ADediting_560993(69327843, -), ADediting_560994(69327845, -), ADediting_560995(69327847, -), ADediting_560996(69327852, -), ADediting_560997(69328011, -), ADediting_560998(69328021, -), ADediting_560999(69328025, -), ADediting_561000(69328027, -), ADediting_561001(69328041, -), ADediting_561002(69328051, -), ADediting_561003(69328054, -), ADediting_561004(69328059, -), ADediting_561005(69328063, -), ADediting_561006(69328064, -), ADediting_561007(69328068, -), ADediting_561008(69328069, -), ADediting_561009(69328076, -), ADediting_561010(69328085, -), ADediting_561011(69328092, -), ADediting_561012(69328095, -), ADediting_561013(69328112, -), ADediting_561014(69328116, -), ADediting_561015(69328118, -), ADediting_561016(69328121, -), ADediting_561017(69328125, -), ADediting_561018(69328130, -), ADediting_561019(69328141, -), ADediting_561020(69328142, -), ADediting_561021(69328151, -), ADediting_561022(69328166, -), ADediting_561023(69328167, -), ADediting_561024(69328175, -), ADediting_561025(69328183, -), ADediting_561026(69328213, -), ADediting_561027(69328218, -), ADediting_561028(69328219, -), ADediting_561029(69328227, -), ADediting_561030(69328235, -), ADediting_561031(69328241, -), ADediting_561032(69331191, -), ADediting_561033(69331261, -), ADediting_561034(69331370, -), ADediting_561035(69331565, -), ADediting_561036(69331588, -), ADediting_561037(69331599, -), ADediting_561038(69331600, -), ADediting_561039(69331659, -), ADediting_561040(69331667, -), ADediting_561041(69331700, -), ADediting_561042(69331733, -), ADediting_561043(69331773, -), ADediting_561044(69331774, -), ADediting_561045(69331790, -), ADediting_561046(69332228, -), ADediting_561047(69332250, -), ADediting_561048(69332263, -), ADediting_561049(69332281, -), ADediting_561050(69333305, -), ADediting_561051(69333785, -), ADediting_1543865(69327362, -), ADediting_1543866(69331676, -), ADediting_1543867(69331681, -), ADediting_1543868(69331714, -),

Top

RNA editing positional annotations for COG8 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_560938	chr16_69327161_-	UTR3
ADediting_560939	chr16_69327197_-	UTR3
ADediting_560940	chr16_69327203_-	UTR3
ADediting_560941	chr16_69327233_-	UTR3
ADediting_560942	chr16_69327235_-	UTR3
ADediting_560943	chr16_69327244_-	UTR3
ADediting_560944	chr16_69327253_-	UTR3
ADediting_560945	chr16_69327257_-	UTR3
ADediting_560946	chr16_69327264_-	UTR3
ADediting_560947	chr16_69327265_-	UTR3
ADediting_560948	chr16_69327266_-	UTR3
ADediting_560949	chr16_69327273_-	UTR3
ADediting_560950	chr16_69327296_-	UTR3
ADediting_560951	chr16_69327300_-	UTR3
ADediting_560952	chr16_69327302_-	UTR3
ADediting_560953	chr16_69327305_-	UTR3
ADediting_560954	chr16_69327306_-	UTR3
ADediting_560955	chr16_69327316_-	UTR3
ADediting_560956	chr16_69327332_-	UTR3
ADediting_560957	chr16_69327335_-	UTR3
ADediting_560958	chr16_69327336_-	UTR3
ADediting_560959	chr16_69327341_-	UTR3
ADediting_560960	chr16_69327343_-	UTR3
ADediting_560961	chr16_69327344_-	UTR3
ADediting_560962	chr16_69327345_-	UTR3
ADediting_560963	chr16_69327346_-	UTR3
ADediting_560964	chr16_69327347_-	UTR3
ADediting_560965	chr16_69327350_-	UTR3
ADediting_560966	chr16_69327361_-	UTR3
ADediting_560967	chr16_69327369_-	UTR3
ADediting_560968	chr16_69327371_-	UTR3
ADediting_560969	chr16_69327372_-	UTR3
ADediting_560970	chr16_69327386_-	UTR3
ADediting_560971	chr16_69327387_-	UTR3
ADediting_560972	chr16_69327392_-	UTR3
ADediting_560973	chr16_69327395_-	UTR3
ADediting_560974	chr16_69327400_-	UTR3
ADediting_560975	chr16_69327405_-	UTR3
ADediting_560976	chr16_69327410_-	UTR3
ADediting_560977	chr16_69327414_-	UTR3
ADediting_560978	chr16_69327418_-	UTR3
ADediting_560979	chr16_69327419_-	UTR3
ADediting_560980	chr16_69327435_-	UTR3
ADediting_560981	chr16_69327440_-	UTR3
ADediting_560982	chr16_69327441_-	UTR3
ADediting_560983	chr16_69327463_-	UTR3
ADediting_560984	chr16_69327755_-	UTR3
ADediting_560985	chr16_69327767_-	UTR3
ADediting_560986	chr16_69327768_-	UTR3
ADediting_560987	chr16_69327790_-	UTR3
ADediting_560988	chr16_69327791_-	UTR3
ADediting_560989	chr16_69327795_-	UTR3
ADediting_560990	chr16_69327809_-	UTR3
ADediting_560991	chr16_69327820_-	UTR3
ADediting_560992	chr16_69327832_-	UTR3
ADediting_560993	chr16_69327843_-	UTR3
ADediting_560994	chr16_69327845_-	UTR3
ADediting_560995	chr16_69327847_-	UTR3
ADediting_560996	chr16_69327852_-	UTR3
ADediting_560997	chr16_69328011_-	UTR3
ADediting_560998	chr16_69328021_-	UTR3
ADediting_560999	chr16_69328025_-	UTR3
ADediting_561000	chr16_69328027_-	UTR3
ADediting_561001	chr16_69328041_-	UTR3
ADediting_561002	chr16_69328051_-	UTR3
ADediting_561003	chr16_69328054_-	UTR3
ADediting_561004	chr16_69328059_-	UTR3
ADediting_561005	chr16_69328063_-	UTR3
ADediting_561006	chr16_69328064_-	UTR3
ADediting_561007	chr16_69328068_-	UTR3
ADediting_561008	chr16_69328069_-	UTR3
ADediting_561009	chr16_69328076_-	UTR3
ADediting_561010	chr16_69328085_-	UTR3
ADediting_561011	chr16_69328092_-	UTR3
ADediting_561012	chr16_69328095_-	UTR3
ADediting_561013	chr16_69328112_-	UTR3
ADediting_561014	chr16_69328116_-	UTR3
ADediting_561015	chr16_69328118_-	UTR3
ADediting_561016	chr16_69328121_-	UTR3
ADediting_561017	chr16_69328125_-	UTR3
ADediting_561018	chr16_69328130_-	UTR3
ADediting_561019	chr16_69328141_-	UTR3
ADediting_561020	chr16_69328142_-	UTR3
ADediting_561021	chr16_69328151_-	UTR3
ADediting_561022	chr16_69328166_-	UTR3
ADediting_561023	chr16_69328167_-	UTR3
ADediting_561024	chr16_69328175_-	UTR3
ADediting_561025	chr16_69328183_-	UTR3
ADediting_561026	chr16_69328213_-	UTR3
ADediting_561027	chr16_69328218_-	UTR3
ADediting_561028	chr16_69328219_-	UTR3
ADediting_561029	chr16_69328227_-	UTR3
ADediting_561030	chr16_69328235_-	UTR3
ADediting_561031	chr16_69328241_-	UTR3
ADediting_561032	chr16_69331191_-	intronic
ADediting_561033	chr16_69331261_-	intronic
ADediting_561034	chr16_69331370_-	intronic
ADediting_561035	chr16_69331565_-	intronic
ADediting_561036	chr16_69331588_-	intronic
ADediting_561037	chr16_69331599_-	intronic
ADediting_561038	chr16_69331600_-	intronic
ADediting_561039	chr16_69331659_-	intronic
ADediting_561040	chr16_69331667_-	intronic
ADediting_561041	chr16_69331700_-	intronic
ADediting_561042	chr16_69331733_-	intronic
ADediting_561043	chr16_69331773_-	intronic
ADediting_561044	chr16_69331774_-	intronic
ADediting_561045	chr16_69331790_-	intronic
ADediting_561046	chr16_69332228_-	intronic
ADediting_561047	chr16_69332250_-	intronic
ADediting_561048	chr16_69332263_-	intronic
ADediting_561049	chr16_69332281_-	intronic
ADediting_561050	chr16_69333305_-	intronic
ADediting_561051	chr16_69333785_-	intronic
ADediting_1543865	chr16_69327362_-	UTR3
ADediting_1543866	chr16_69331676_-	intronic
ADediting_1543867	chr16_69331681_-	intronic
ADediting_1543868	chr16_69331714_-	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_560938	chr16_69327161_-	SINE	Alu	Name=AluSx1
ADediting_560939	chr16_69327197_-	SINE	Alu	Name=AluSx1
ADediting_560940	chr16_69327203_-	SINE	Alu	Name=AluSx1
ADediting_560941	chr16_69327233_-	SINE	Alu	Name=AluSx1
ADediting_560942	chr16_69327235_-	SINE	Alu	Name=AluSx1
ADediting_560943	chr16_69327244_-	SINE	Alu	Name=AluSx1
ADediting_560944	chr16_69327253_-	SINE	Alu	Name=AluSx1
ADediting_560945	chr16_69327257_-	SINE	Alu	Name=AluSx1
ADediting_560946	chr16_69327264_-	SINE	Alu	Name=AluSx1
ADediting_560947	chr16_69327265_-	SINE	Alu	Name=AluSx1
ADediting_560948	chr16_69327266_-	SINE	Alu	Name=AluSx1
ADediting_560949	chr16_69327273_-	SINE	Alu	Name=AluSx1
ADediting_560950	chr16_69327296_-	SINE	Alu	Name=AluSx1
ADediting_560951	chr16_69327300_-	SINE	Alu	Name=AluSx1
ADediting_560952	chr16_69327302_-	SINE	Alu	Name=AluSx1
ADediting_560953	chr16_69327305_-	SINE	Alu	Name=AluSx1
ADediting_560954	chr16_69327306_-	SINE	Alu	Name=AluSx1
ADediting_560955	chr16_69327316_-	SINE	Alu	Name=AluSx1
ADediting_560956	chr16_69327332_-	SINE	Alu	Name=AluSx1
ADediting_560957	chr16_69327335_-	SINE	Alu	Name=AluSx1
ADediting_560958	chr16_69327336_-	SINE	Alu	Name=AluSx1
ADediting_560959	chr16_69327341_-	SINE	Alu	Name=AluSx1
ADediting_560960	chr16_69327343_-	SINE	Alu	Name=AluSx1
ADediting_560961	chr16_69327344_-	SINE	Alu	Name=AluSx1
ADediting_560962	chr16_69327345_-	SINE	Alu	Name=AluSx1
ADediting_560963	chr16_69327346_-	SINE	Alu	Name=AluSx1
ADediting_560964	chr16_69327347_-	SINE	Alu	Name=AluSx1
ADediting_560965	chr16_69327350_-	SINE	Alu	Name=AluSx1
ADediting_560966	chr16_69327361_-	SINE	Alu	Name=AluSx1
ADediting_560967	chr16_69327369_-	SINE	Alu	Name=AluSx1
ADediting_560968	chr16_69327371_-	SINE	Alu	Name=AluSx1
ADediting_560969	chr16_69327372_-	SINE	Alu	Name=AluSx1
ADediting_560970	chr16_69327386_-	SINE	Alu	Name=AluSx1
ADediting_560971	chr16_69327387_-	SINE	Alu	Name=AluSx1
ADediting_560972	chr16_69327392_-	SINE	Alu	Name=AluSx1
ADediting_560973	chr16_69327395_-	SINE	Alu	Name=AluSx1
ADediting_560974	chr16_69327400_-	SINE	Alu	Name=AluSx1
ADediting_560975	chr16_69327405_-	SINE	Alu	Name=AluSx1
ADediting_560976	chr16_69327410_-	SINE	Alu	Name=AluSx1
ADediting_560977	chr16_69327414_-	SINE	Alu	Name=AluSx1
ADediting_560978	chr16_69327418_-	SINE	Alu	Name=AluSx1
ADediting_560979	chr16_69327419_-	SINE	Alu	Name=AluSx1
ADediting_560980	chr16_69327435_-	SINE	Alu	Name=AluSx1
ADediting_560981	chr16_69327440_-	SINE	Alu	Name=AluSx1
ADediting_560982	chr16_69327441_-	SINE	Alu	Name=AluSx1
ADediting_560983	chr16_69327463_-	SINE	Alu	Name=AluSx1
ADediting_560984	chr16_69327755_-	SINE	Alu	Name=FLAM_C
ADediting_560985	chr16_69327767_-	SINE	Alu	Name=FLAM_C
ADediting_560986	chr16_69327768_-	SINE	Alu	Name=FLAM_C
ADediting_560987	chr16_69327790_-	SINE	Alu	Name=FLAM_C
ADediting_560988	chr16_69327791_-	SINE	Alu	Name=FLAM_C
ADediting_560989	chr16_69327795_-	SINE	Alu	Name=FLAM_C
ADediting_560990	chr16_69327809_-	SINE	Alu	Name=FLAM_C
ADediting_560991	chr16_69327820_-	SINE	Alu	Name=FLAM_C
ADediting_560992	chr16_69327832_-	SINE	Alu	Name=FLAM_C
ADediting_560993	chr16_69327843_-	SINE	Alu	Name=FLAM_C
ADediting_560994	chr16_69327845_-	SINE	Alu	Name=FLAM_C
ADediting_560995	chr16_69327847_-	SINE	Alu	Name=FLAM_C
ADediting_560996	chr16_69327852_-	SINE	Alu	Name=FLAM_C
ADediting_560997	chr16_69328011_-	SINE	Alu	Name=AluSg7
ADediting_560998	chr16_69328021_-	SINE	Alu	Name=AluSg7
ADediting_560999	chr16_69328025_-	SINE	Alu	Name=AluSg7
ADediting_561000	chr16_69328027_-	SINE	Alu	Name=AluSg7
ADediting_561001	chr16_69328041_-	SINE	Alu	Name=AluSg7
ADediting_561002	chr16_69328051_-	SINE	Alu	Name=AluSg7
ADediting_561003	chr16_69328054_-	SINE	Alu	Name=AluSg7
ADediting_561004	chr16_69328059_-	SINE	Alu	Name=AluSg7
ADediting_561005	chr16_69328063_-	SINE	Alu	Name=AluSg7
ADediting_561006	chr16_69328064_-	SINE	Alu	Name=AluSg7
ADediting_561007	chr16_69328068_-	SINE	Alu	Name=AluSg7
ADediting_561008	chr16_69328069_-	SINE	Alu	Name=AluSg7
ADediting_561009	chr16_69328076_-	SINE	Alu	Name=AluSg7
ADediting_561010	chr16_69328085_-	SINE	Alu	Name=AluSg7
ADediting_561011	chr16_69328092_-	SINE	Alu	Name=AluSg7
ADediting_561012	chr16_69328095_-	SINE	Alu	Name=AluSg7
ADediting_561013	chr16_69328112_-	SINE	Alu	Name=AluSg7
ADediting_561014	chr16_69328116_-	SINE	Alu	Name=AluSg7
ADediting_561015	chr16_69328118_-	SINE	Alu	Name=AluSg7
ADediting_561016	chr16_69328121_-	SINE	Alu	Name=AluSg7
ADediting_561017	chr16_69328125_-	SINE	Alu	Name=AluSg7
ADediting_561018	chr16_69328130_-	SINE	Alu	Name=AluSg7
ADediting_561019	chr16_69328141_-	SINE	Alu	Name=AluSg7
ADediting_561020	chr16_69328142_-	SINE	Alu	Name=AluSg7
ADediting_561021	chr16_69328151_-	SINE	Alu	Name=AluSg7
ADediting_561022	chr16_69328166_-	SINE	Alu	Name=AluSg7
ADediting_561023	chr16_69328167_-	SINE	Alu	Name=AluSg7
ADediting_561024	chr16_69328175_-	SINE	Alu	Name=AluSg7
ADediting_561025	chr16_69328183_-	SINE	Alu	Name=AluSg7
ADediting_561026	chr16_69328213_-	SINE	Alu	Name=AluSg7
ADediting_561027	chr16_69328218_-	SINE	Alu	Name=AluSg7
ADediting_561028	chr16_69328219_-	SINE	Alu	Name=AluSg7
ADediting_561029	chr16_69328227_-	SINE	Alu	Name=AluSg7
ADediting_561030	chr16_69328235_-	SINE	Alu	Name=AluSg7
ADediting_561031	chr16_69328241_-	SINE	Alu	Name=AluSg7
ADediting_561032	chr16_69331191_-	SINE	Alu	Name=AluSp
ADediting_561033	chr16_69331261_-	SINE	Alu	Name=AluSp
ADediting_561034	chr16_69331370_-	SINE	Alu	Name=AluSp
ADediting_561035	chr16_69331565_-	SINE	Alu	Name=AluSx1
ADediting_561036	chr16_69331588_-	SINE	Alu	Name=AluSx1
ADediting_561037	chr16_69331599_-	SINE	Alu	Name=AluSx1
ADediting_561038	chr16_69331600_-	SINE	Alu	Name=AluSx1
ADediting_561039	chr16_69331659_-	SINE	Alu	Name=AluSx1
ADediting_561040	chr16_69331667_-	SINE	Alu	Name=AluSx1
ADediting_561041	chr16_69331700_-	SINE	Alu	Name=AluSx1
ADediting_561042	chr16_69331733_-	SINE	Alu	Name=AluSx1
ADediting_561043	chr16_69331773_-	SINE	Alu	Name=AluSx1
ADediting_561044	chr16_69331774_-	SINE	Alu	Name=AluSx1
ADediting_561045	chr16_69331790_-	SINE	Alu	Name=AluSx1
ADediting_561046	chr16_69332228_-	SINE	Alu	Name=AluSc
ADediting_561047	chr16_69332250_-	SINE	Alu	Name=AluSc
ADediting_561048	chr16_69332263_-	SINE	Alu	Name=AluSc
ADediting_561049	chr16_69332281_-	SINE	Alu	Name=AluSc
ADediting_561050	chr16_69333305_-	SINE	Alu	Name=AluJr
ADediting_561051	chr16_69333785_-	SINE	Alu	Name=AluJo
ADediting_1543865	chr16_69327362_-	SINE	Alu	Name=AluSx1
ADediting_1543866	chr16_69331676_-	SINE	Alu	Name=AluSx1
ADediting_1543867	chr16_69331681_-	SINE	Alu	Name=AluSx1
ADediting_1543868	chr16_69331714_-	SINE	Alu	Name=AluSx1

Top

RNA A-to-I editing events in the alternative splicing sites for COG8

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for COG8

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

Top

Protein coding region RNA A-to-I editings for COG8

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for COG8

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_560938	chr16_69327161_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6832-3p	chr16	69327159	69327165	7mer-m8	69327158	69327177	159	-9.85
ADediting_560939	chr16_69327197_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1233-3p	chr16	69327192	69327198	7mer-m8	69327191	69327210	158	-23.39
ADediting_560939	chr16_69327197_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3663-5p	chr16	69327197	69327203	7mer-m8	69327196	69327218	148	-25.09
ADediting_560939	chr16_69327197_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6779-3p	chr16	69327193	69327199	7mer-m8	69327192	69327214	156	-21.51
ADediting_560940	chr16_69327203_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1181	chr16	69327203	69327209	7mer-m8	69327202	69327222	142	-22.01
ADediting_560941	chr16_69327233_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-769-5p	chr16	69327229	69327235	7mer-m8	69327228	69327249	154	-23.47
ADediting_560942	chr16_69327235_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-7977	chr16	69327233	69327239	7mer-m8	69327232	69327250	158	-23.76
ADediting_560944	chr16_69327253_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1281	chr16	69327253	69327259	7mer-m8	69327252	69327268	141	-17.01
ADediting_560945	chr16_69327257_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1913	chr16	69327251	69327258	8mer-1a	69327251	69327272	148	-21.45
ADediting_560945	chr16_69327257_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-361-3p	chr16	69327256	69327262	7mer-m8	69327255	69327281	165	-32.41
ADediting_560947	chr16_69327265_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4303	chr16	69327264	69327270	7mer-m8	69327263	69327278	141	-11.55
ADediting_560949	chr16_69327273_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4431	chr16	69327270	69327276	7mer-m8	69327269	69327290	140	-17.94
ADediting_560950	chr16_69327296_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-646	chr16	69327294	69327300	7mer-m8	69327293	69327311	145	-16.35
ADediting_560954	chr16_69327306_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-513a-5p	chr16	69327305	69327311	7mer-m8	69327304	69327321	140	-14.37
ADediting_560955	chr16_69327316_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1226-3p	chr16	69327316	69327322	7mer-m8	69327315	69327336	142	-19.71
ADediting_560959	chr16_69327341_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-153-5p	chr16	69327341	69327347	7mer-m8	69327340	69327360	146	-11.96
ADediting_560959	chr16_69327341_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-23a-3p	chr16	69327337	69327344	8mer-1a	69327337	69327358	143	-10.08
ADediting_560959	chr16_69327341_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-23b-3p	chr16	69327337	69327344	8mer-1a	69327337	69327360	143	-10.08
ADediting_560959	chr16_69327341_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-23c	chr16	69327337	69327344	8mer-1a	69327337	69327358	148	-11.26
ADediting_560960	chr16_69327343_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1-5p	chr16	69327338	69327345	8mer-1a	69327338	69327360	145	-6.88
ADediting_560963	chr16_69327346_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-325	chr16	69327345	69327352	8mer-1a	69327345	69327365	146	-14.92
ADediting_560964	chr16_69327347_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-222-5p	chr16	69327345	69327352	8mer-1a	69327345	69327368	154	-18.83
ADediting_560964	chr16_69327347_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-30a-3p	chr16	69327343	69327350	8mer-1a	69327343	69327369	153	-14.18
ADediting_560964	chr16_69327347_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-30d-3p	chr16	69327343	69327350	8mer-1a	69327343	69327369	149	-14.85
ADediting_560964	chr16_69327347_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-30e-3p	chr16	69327343	69327350	8mer-1a	69327343	69327368	152	-13.99
ADediting_560964	chr16_69327347_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-936	chr16	69327346	69327353	8mer-1a	69327346	69327368	159	-22.91
ADediting_560965	chr16_69327350_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-374b-3p	chr16	69327345	69327352	8mer-1a	69327345	69327367	144	-9.82
ADediting_560966	chr16_69327361_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-520f-3p	chr16	69327357	69327363	7mer-m8	69327356	69327377	147	-15.32
ADediting_560967	chr16_69327369_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1306-3p	chr16	69327369	69327375	7mer-m8	69327368	69327385	152	-23.71
ADediting_560968	chr16_69327371_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3190-5p	chr16	69327371	69327377	7mer-m8	69327370	69327389	152	-19.64
ADediting_560970	chr16_69327386_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-12113	chr16	69327386	69327392	7mer-m8	69327385	69327405	147	-19.86
ADediting_560970	chr16_69327386_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4539	chr16	69327386	69327392	7mer-m8	69327385	69327404	151	-20
ADediting_560972	chr16_69327392_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4732-3p	chr16	69327392	69327398	7mer-m8	69327391	69327411	155	-23.59
ADediting_560974	chr16_69327400_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4726-3p	chr16	69327399	69327405	7mer-m8	69327398	69327420	150	-23.19
ADediting_560976	chr16_69327410_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4485-5p	chr16	69327408	69327415	8mer-1a	69327408	69327423	150	-22.86
ADediting_560977	chr16_69327414_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4707-3p	chr16	69327410	69327417	8mer-1a	69327410	69327435	150	-27
ADediting_560978	chr16_69327418_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-18a-3p	chr16	69327413	69327419	7mer-m8	69327412	69327434	148	-20.49
ADediting_560978	chr16_69327418_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4732-3p	chr16	69327416	69327422	7mer-m8	69327415	69327435	153	-26.39
ADediting_560978	chr16_69327418_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-7976	chr16	69327414	69327421	8mer-1a	69327414	69327431	142	-18.48
ADediting_560978	chr16_69327418_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-874-3p	chr16	69327414	69327420	7mer-m8	69327413	69327436	152	-29.94
ADediting_560980	chr16_69327435_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-371a-3p	chr16	69327430	69327436	7mer-m8	69327429	69327451	144	-15.05
ADediting_560981	chr16_69327440_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8052	chr16	69327435	69327441	7mer-1a	69327435	69327453	148	-29.06
ADediting_560982	chr16_69327441_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-513a-5p	chr16	69327440	69327446	7mer-m8	69327439	69327456	152	-17.32
ADediting_560982	chr16_69327441_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-638	chr16	69327435	69327441	7mer-1a	69327435	69327459	155	-34.38
ADediting_560983	chr16_69327463_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3940-3p	chr16	69327459	69327465	7mer-m8	69327458	69327479	140	-17.58
ADediting_560983	chr16_69327463_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6850-3p	chr16	69327462	69327468	7mer-m8	69327461	69327480	151	-27.57
ADediting_560985	chr16_69327767_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3189-3p	chr16	69327766	69327772	7mer-m8	69327765	69327784	145	-25.82
ADediting_560985	chr16_69327767_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6813-3p	chr16	69327765	69327771	7mer-m8	69327764	69327784	140	-12.15
ADediting_560986	chr16_69327768_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-326	chr16	69327766	69327772	7mer-m8	69327765	69327784	140	-14.6
ADediting_560986	chr16_69327768_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-330-5p	chr16	69327766	69327772	7mer-m8	69327765	69327786	140	-21.43
ADediting_560986	chr16_69327768_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4314	chr16	69327767	69327773	7mer-m8	69327766	69327783	140	-21.61
ADediting_560986	chr16_69327768_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-514a-5p	chr16	69327765	69327771	7mer-m8	69327764	69327787	146	-18.62
ADediting_560987	chr16_69327790_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1288-3p	chr16	69327787	69327793	7mer-m8	69327786	69327807	158	-27.67
ADediting_560987	chr16_69327790_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3169	chr16	69327786	69327792	7mer-m8	69327785	69327804	151	-18.63
ADediting_560987	chr16_69327790_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5002-3p	chr16	69327788	69327794	7mer-m8	69327787	69327805	159	-20.74
ADediting_560988	chr16_69327791_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6078	chr16	69327790	69327797	8mer-1a	69327790	69327809	152	-20.35
ADediting_560989	chr16_69327795_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4740-3p	chr16	69327793	69327799	7mer-m8	69327792	69327813	140	-18.47
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3940-3p	chr16	69327816	69327822	7mer-m8	69327815	69327836	142	-21.15
ADediting_560992	chr16_69327832_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-451b	chr16	69327829	69327836	8mer-1a	69327829	69327850	148	-13.99
ADediting_560992	chr16_69327832_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4696	chr16	69327831	69327837	7mer-m8	69327830	69327854	143	-19.24
ADediting_560994	chr16_69327845_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-454-5p	chr16	69327843	69327850	8mer-1a	69327843	69327864	140	-11.88
ADediting_560994	chr16_69327845_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6883-3p	chr16	69327843	69327849	7mer-m8	69327842	69327863	152	-13.82
ADediting_560996	chr16_69327852_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-371b-5p	chr16	69327849	69327856	8mer-1a	69327849	69327870	146	-8.63
ADediting_560996	chr16_69327852_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-373-5p	chr16	69327849	69327856	8mer-1a	69327849	69327870	142	-8.61
ADediting_560996	chr16_69327852_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-616-5p	chr16	69327849	69327856	8mer-1a	69327849	69327870	140	-5.92
ADediting_560997	chr16_69328011_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4634	chr16	69328006	69328013	8mer-1a	69328006	69328026	146	-21.85
ADediting_560998	chr16_69328021_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4690-3p	chr16	69328016	69328023	8mer-1a	69328016	69328035	165	-30.74
ADediting_560998	chr16_69328021_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5685	chr16	69328016	69328023	8mer-1a	69328016	69328036	153	-19.71
ADediting_561000	chr16_69328027_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4772-3p	chr16	69328024	69328030	7mer-m8	69328023	69328045	158	-20.38
ADediting_561003	chr16_69328054_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6817-3p	chr16	69328054	69328060	7mer-m8	69328053	69328071	147	-20.32
ADediting_561005	chr16_69328063_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-18a-3p	chr16	69328057	69328064	8mer-1a	69328057	69328079	140	-15.72
ADediting_561005	chr16_69328063_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-874-3p	chr16	69328059	69328065	7mer-m8	69328058	69328082	153	-29.81
ADediting_561006	chr16_69328064_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4638-5p	chr16	69328062	69328068	7mer-m8	69328061	69328084	145	-21.76
ADediting_561007	chr16_69328068_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6878-3p	chr16	69328063	69328070	8mer-1a	69328063	69328083	140	-11.74
ADediting_561008	chr16_69328069_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8057	chr16	69328063	69328069	7mer-1a	69328063	69328083	140	-19.98
ADediting_561009	chr16_69328076_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1207-3p	chr16	69328076	69328082	7mer-m8	69328075	69328092	140	-12.56
ADediting_561009	chr16_69328076_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-646	chr16	69328074	69328080	7mer-m8	69328073	69328091	145	-14.99
ADediting_561010	chr16_69328085_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8052	chr16	69328080	69328086	7mer-1a	69328080	69328100	141	-20.59
ADediting_561012	chr16_69328095_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4258	chr16	69328094	69328100	7mer-m8	69328093	69328109	156	-29
ADediting_561012	chr16_69328095_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4707-3p	chr16	69328092	69328099	8mer-1a	69328092	69328114	156	-31.23
ADediting_561014	chr16_69328116_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6844	chr16	69328115	69328121	7mer-m8	69328114	69328135	151	-7.63
ADediting_561016	chr16_69328121_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3680-3p	chr16	69328116	69328123	8mer-1a	69328116	69328136	144	-15.16
ADediting_561018	chr16_69328130_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-374b-3p	chr16	69328125	69328132	8mer-1a	69328125	69328150	146	-14.99
ADediting_561019	chr16_69328141_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3158-3p	chr16	69328137	69328143	7mer-m8	69328136	69328161	157	-26.16
ADediting_561019	chr16_69328141_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-412-3p	chr16	69328141	69328147	7mer-m8	69328140	69328162	145	-17.3
ADediting_561019	chr16_69328141_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6754-3p	chr16	69328141	69328147	7mer-m8	69328140	69328160	150	-18.21
ADediting_561020	chr16_69328142_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1182	chr16	69328137	69328143	7mer-m8	69328136	69328158	142	-13.88
ADediting_561020	chr16_69328142_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1229-3p	chr16	69328141	69328147	7mer-m8	69328140	69328164	149	-16.67
ADediting_561020	chr16_69328142_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6511a-3p	chr16	69328141	69328148	8mer-1a	69328141	69328162	150	-19.08
ADediting_561020	chr16_69328142_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6511b-3p	chr16	69328141	69328148	8mer-1a	69328141	69328164	144	-17.51
ADediting_561021	chr16_69328151_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3190-5p	chr16	69328151	69328157	7mer-m8	69328150	69328169	152	-21.42
ADediting_561021	chr16_69328151_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4793-5p	chr16	69328147	69328153	7mer-m8	69328146	69328170	144	-19.81
ADediting_561022	chr16_69328166_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1200	chr16	69328164	69328170	7mer-m8	69328163	69328182	160	-26.74
ADediting_561023	chr16_69328167_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-516a-5p	chr16	69328164	69328170	7mer-m8	69328163	69328185	140	-14.63
ADediting_561026	chr16_69328213_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-371a-3p	chr16	69328208	69328214	7mer-m8	69328207	69328229	145	-17.36
ADediting_561027	chr16_69328218_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8052	chr16	69328213	69328219	7mer-1a	69328213	69328231	140	-21.99
ADediting_561028	chr16_69328219_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-513a-5p	chr16	69328218	69328224	7mer-m8	69328217	69328234	140	-14.58
ADediting_561028	chr16_69328219_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-638	chr16	69328213	69328219	7mer-1a	69328213	69328237	153	-30.97
ADediting_561029	chr16_69328227_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4634	chr16	69328223	69328229	7mer-m8	69328222	69328240	145	-20.24
ADediting_561031	chr16_69328241_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-941	chr16	69328238	69328244	7mer-m8	69328237	69328259	147	-22.04

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_560938	chr16_69327161_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-204-5p	chr16	69327156	69327163	8mer-1a	69327156	69327177	142	-10.74
ADediting_560938	chr16_69327161_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-211-5p	chr16	69327156	69327163	8mer-1a	69327156	69327177	145	-10.74
ADediting_560938	chr16_69327161_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4755-5p	chr16	69327156	69327162	7mer-m8	69327155	69327176	140	-10.78
ADediting_560938	chr16_69327161_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5006-3p	chr16	69327156	69327162	7mer-m8	69327155	69327175	145	-10.57
ADediting_560938	chr16_69327161_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6832-3p	chr16	69327157	69327164	8mer-1a	69327157	69327176	159	-9.61
ADediting_560940	chr16_69327203_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-7107-3p	chr16	69327198	69327205	8mer-1a	69327198	69327224	141	-19.97
ADediting_560942	chr16_69327235_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6787-3p	chr16	69327233	69327239	7mer-1a	69327233	69327257	150	-29.01
ADediting_560943	chr16_69327244_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-324-3p	chr16	69327240	69327246	7mer-m8	69327239	69327261	149	-24.32
ADediting_560944	chr16_69327253_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6836-3p	chr16	69327253	69327259	7mer-m8	69327252	69327272	145	-18.68
ADediting_560945	chr16_69327257_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6778-3p	chr16	69327253	69327260	8mer-1a	69327253	69327273	142	-17.34
ADediting_560945	chr16_69327257_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6836-3p	chr16	69327253	69327259	7mer-m8	69327252	69327272	145	-18.68
ADediting_560946	chr16_69327264_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4464	chr16	69327261	69327267	7mer-m8	69327260	69327279	147	-12.62
ADediting_560946	chr16_69327264_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4748	chr16	69327261	69327267	7mer-m8	69327260	69327278	151	-14.65
ADediting_560946	chr16_69327264_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8055	chr16	69327264	69327270	7mer-m8	69327263	69327285	140	-10.27
ADediting_560947	chr16_69327265_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4464	chr16	69327261	69327267	7mer-m8	69327260	69327279	147	-12.62
ADediting_560947	chr16_69327265_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4748	chr16	69327261	69327267	7mer-m8	69327260	69327278	151	-14.65
ADediting_560947	chr16_69327265_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8055	chr16	69327264	69327270	7mer-m8	69327263	69327285	140	-10.27
ADediting_560948	chr16_69327266_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4464	chr16	69327261	69327267	7mer-m8	69327260	69327279	147	-12.62
ADediting_560948	chr16_69327266_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4748	chr16	69327261	69327267	7mer-m8	69327260	69327278	151	-14.65
ADediting_560948	chr16_69327266_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5708	chr16	69327265	69327272	8mer-1a	69327265	69327284	151	-19.57
ADediting_560948	chr16_69327266_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-8055	chr16	69327264	69327270	7mer-m8	69327263	69327285	140	-10.27
ADediting_560949	chr16_69327273_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-629-3p	chr16	69327273	69327279	7mer-m8	69327272	69327292	152	-22.1
ADediting_560950	chr16_69327296_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-562	chr16	69327293	69327299	7mer-m8	69327292	69327311	155	-14.44
ADediting_560951	chr16_69327300_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4679	chr16	69327299	69327305	7mer-m8	69327298	69327320	149	-13.36
ADediting_560952	chr16_69327302_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4679	chr16	69327299	69327305	7mer-m8	69327298	69327320	149	-13.36
ADediting_560953	chr16_69327305_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69327304	69327310	7mer-m8	69327303	69327324	147	-15.44
ADediting_560953	chr16_69327305_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6504-3p	chr16	69327304	69327310	7mer-m8	69327303	69327324	142	-11.31
ADediting_560954	chr16_69327306_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69327304	69327310	7mer-m8	69327303	69327324	147	-15.44
ADediting_560954	chr16_69327306_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6504-3p	chr16	69327304	69327310	7mer-m8	69327303	69327324	142	-11.31
ADediting_560954	chr16_69327306_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-7151-3p	chr16	69327305	69327312	8mer-1a	69327305	69327325	142	-14
ADediting_560956	chr16_69327332_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4735-5p	chr16	69327331	69327337	7mer-m8	69327330	69327351	148	-5.48
ADediting_560956	chr16_69327332_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4775	chr16	69327332	69327338	7mer-m8	69327331	69327353	153	-6.96
ADediting_560957	chr16_69327335_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-335-3p	chr16	69327335	69327341	7mer-m8	69327334	69327354	146	-4.4
ADediting_560957	chr16_69327335_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4735-5p	chr16	69327331	69327337	7mer-m8	69327330	69327351	148	-5.48
ADediting_560957	chr16_69327335_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4775	chr16	69327332	69327338	7mer-m8	69327331	69327353	153	-6.96
ADediting_560958	chr16_69327336_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-335-3p	chr16	69327335	69327341	7mer-m8	69327334	69327354	146	-4.4
ADediting_560958	chr16_69327336_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4735-5p	chr16	69327331	69327337	7mer-m8	69327330	69327351	148	-5.48
ADediting_560958	chr16_69327336_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4775	chr16	69327332	69327338	7mer-m8	69327331	69327353	153	-6.96
ADediting_560967	chr16_69327369_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4716-5p	chr16	69327366	69327372	7mer-m8	69327365	69327386	140	-10.69
ADediting_560967	chr16_69327369_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4781-3p	chr16	69327368	69327374	7mer-m8	69327367	69327385	144	-13.86
ADediting_560968	chr16_69327371_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4716-5p	chr16	69327366	69327372	7mer-m8	69327365	69327386	140	-10.69
ADediting_560968	chr16_69327371_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4781-3p	chr16	69327368	69327374	7mer-m8	69327367	69327385	144	-13.86
ADediting_560969	chr16_69327372_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4435	chr16	69327371	69327378	8mer-1a	69327371	69327391	146	-17.76
ADediting_560969	chr16_69327372_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4781-3p	chr16	69327368	69327374	7mer-m8	69327367	69327385	144	-13.86
ADediting_560972	chr16_69327392_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4680-5p	chr16	69327387	69327393	7mer-1a	69327387	69327407	146	-20.51
ADediting_560975	chr16_69327405_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-125a-3p	chr16	69327400	69327407	8mer-1a	69327400	69327421	152	-18.07
ADediting_560976	chr16_69327410_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5001-3p	chr16	69327408	69327414	7mer-m8	69327407	69327428	148	-18
ADediting_560977	chr16_69327414_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6747-3p	chr16	69327412	69327418	7mer-m8	69327411	69327432	154	-22.42
ADediting_560978	chr16_69327418_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10397-5p	chr16	69327416	69327422	7mer-m8	69327415	69327441	151	-23.21
ADediting_560979	chr16_69327419_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10397-5p	chr16	69327416	69327422	7mer-m8	69327415	69327441	151	-23.21
ADediting_560980	chr16_69327435_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5089-5p	chr16	69327435	69327441	7mer-m8	69327434	69327453	146	-13.24
ADediting_560980	chr16_69327435_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-512-3p	chr16	69327430	69327436	7mer-m8	69327429	69327450	149	-15
ADediting_560980	chr16_69327435_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6506-5p	chr16	69327434	69327440	7mer-m8	69327433	69327455	144	-16.21
ADediting_560981	chr16_69327440_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69327439	69327445	7mer-m8	69327438	69327459	144	-10.33
ADediting_560981	chr16_69327440_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5089-5p	chr16	69327435	69327441	7mer-m8	69327434	69327453	146	-13.24
ADediting_560982	chr16_69327441_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69327439	69327445	7mer-m8	69327438	69327459	144	-10.33
ADediting_560982	chr16_69327441_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-7151-3p	chr16	69327440	69327447	8mer-1a	69327440	69327456	146	-17.62
ADediting_560984	chr16_69327755_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3151-3p	chr16	69327754	69327760	7mer-m8	69327753	69327773	151	-16.94
ADediting_560986	chr16_69327768_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-887-5p	chr16	69327767	69327774	8mer-1a	69327767	69327788	148	-16.01
ADediting_560989	chr16_69327795_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4324	chr16	69327793	69327799	7mer-m8	69327792	69327811	150	-17.12
ADediting_560989	chr16_69327795_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4329	chr16	69327794	69327800	7mer-m8	69327793	69327812	146	-18.91
ADediting_560990	chr16_69327809_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1304-5p	chr16	69327807	69327814	8mer-1a	69327807	69327828	149	-15.35
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3187-5p	chr16	69327819	69327825	7mer-m8	69327818	69327841	155	-28.12
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5189-5p	chr16	69327819	69327825	7mer-m8	69327818	69327840	147	-20.81
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-612	chr16	69327819	69327825	7mer-m8	69327818	69327841	153	-23.53
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-661	chr16	69327817	69327823	7mer-m8	69327816	69327840	142	-20.45
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6860	chr16	69327819	69327825	7mer-m8	69327818	69327836	148	-22.51
ADediting_560991	chr16_69327820_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-939-3p	chr16	69327818	69327824	7mer-m8	69327817	69327837	140	-15.63
ADediting_560993	chr16_69327843_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-340-3p	chr16	69327840	69327846	7mer-m8	69327839	69327858	149	-15.89
ADediting_560993	chr16_69327843_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6827-3p	chr16	69327840	69327846	7mer-m8	69327839	69327860	151	-17.41
ADediting_560994	chr16_69327845_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-340-3p	chr16	69327840	69327846	7mer-m8	69327839	69327858	149	-15.89
ADediting_560994	chr16_69327845_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6827-3p	chr16	69327840	69327846	7mer-m8	69327839	69327860	151	-17.41
ADediting_561001	chr16_69328041_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-1343-3p	chr16	69328038	69328044	7mer-m8	69328037	69328060	143	-22.04
ADediting_561001	chr16_69328041_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6742-3p	chr16	69328038	69328045	8mer-1a	69328038	69328057	145	-14.93
ADediting_561001	chr16_69328041_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6783-3p	chr16	69328038	69328044	7mer-m8	69328037	69328057	146	-18.95
ADediting_561002	chr16_69328051_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-26a-5p	chr16	69328045	69328052	8mer-1a	69328045	69328066	152	-12.33
ADediting_561002	chr16_69328051_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4465	chr16	69328045	69328052	8mer-1a	69328045	69328069	150	-19.28
ADediting_561003	chr16_69328054_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5571-5p	chr16	69328051	69328058	8mer-1a	69328051	69328071	140	-9.36
ADediting_561004	chr16_69328059_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5001-3p	chr16	69328057	69328063	7mer-m8	69328056	69328078	144	-15.33
ADediting_561010	chr16_69328085_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69328084	69328090	7mer-m8	69328083	69328103	148	-12.64
ADediting_561010	chr16_69328085_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5089-5p	chr16	69328080	69328086	7mer-m8	69328079	69328097	146	-13.57
ADediting_561010	chr16_69328085_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6504-3p	chr16	69328084	69328090	7mer-m8	69328083	69328104	143	-13.49
ADediting_561011	chr16_69328092_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3907	chr16	69328090	69328096	7mer-m8	69328089	69328111	146	-22.99
ADediting_561011	chr16_69328092_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-552-3p	chr16	69328086	69328093	8mer-1a	69328086	69328105	150	-17.77
ADediting_561011	chr16_69328092_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-764	chr16	69328088	69328094	7mer-m8	69328087	69328108	153	-24.57
ADediting_561012	chr16_69328095_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3907	chr16	69328090	69328096	7mer-m8	69328089	69328111	146	-22.99
ADediting_561012	chr16_69328095_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6788-3p	chr16	69328095	69328101	7mer-m8	69328094	69328113	153	-23.26
ADediting_561013	chr16_69328112_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4735-5p	chr16	69328111	69328117	7mer-m8	69328110	69328131	148	-8.95
ADediting_561014	chr16_69328116_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4735-5p	chr16	69328111	69328117	7mer-m8	69328110	69328131	148	-8.95
ADediting_561018	chr16_69328130_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6832-5p	chr16	69328129	69328135	7mer-m8	69328128	69328150	140	-18.87
ADediting_561019	chr16_69328141_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6823-5p	chr16	69328136	69328142	7mer-m8	69328135	69328155	140	-14.24
ADediting_561022	chr16_69328166_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-526b-5p	chr16	69328164	69328170	7mer-m8	69328163	69328185	141	-12.98
ADediting_561023	chr16_69328167_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-526b-5p	chr16	69328164	69328170	7mer-m8	69328163	69328185	141	-12.98
ADediting_561025	chr16_69328183_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-640	chr16	69328183	69328189	7mer-m8	69328182	69328203	146	-23.32
ADediting_561026	chr16_69328213_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5089-5p	chr16	69328213	69328219	7mer-m8	69328212	69328232	144	-11.97
ADediting_561026	chr16_69328213_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-512-3p	chr16	69328208	69328214	7mer-m8	69328207	69328228	149	-15.51
ADediting_561026	chr16_69328213_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6506-5p	chr16	69328212	69328218	7mer-m8	69328211	69328236	148	-18.89
ADediting_561027	chr16_69328218_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69328217	69328223	7mer-m8	69328216	69328237	144	-10.14
ADediting_561027	chr16_69328218_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-5089-5p	chr16	69328213	69328219	7mer-m8	69328212	69328232	144	-11.97
ADediting_561027	chr16_69328218_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6504-3p	chr16	69328217	69328223	7mer-m8	69328216	69328237	148	-12.95
ADediting_561028	chr16_69328219_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-10399-5p	chr16	69328217	69328223	7mer-m8	69328216	69328237	144	-10.14
ADediting_561028	chr16_69328219_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6504-3p	chr16	69328217	69328223	7mer-m8	69328216	69328237	148	-12.95
ADediting_561028	chr16_69328219_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-7151-3p	chr16	69328218	69328225	8mer-1a	69328218	69328238	150	-15.24
ADediting_561030	chr16_69328235_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3130-3p	chr16	69328234	69328240	7mer-m8	69328233	69328254	150	-20.99
ADediting_561031	chr16_69328241_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-3190-5p	chr16	69328240	69328246	7mer-m8	69328239	69328258	143	-16.29
ADediting_561031	chr16_69328241_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-4701-5p	chr16	69328241	69328247	7mer-m8	69328240	69328266	149	-20.46
ADediting_561031	chr16_69328241_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-588	chr16	69328241	69328247	7mer-m8	69328240	69328258	144	-15.11
ADediting_561031	chr16_69328241_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6765-3p	chr16	69328237	69328243	7mer-m8	69328236	69328256	147	-17.92
ADediting_561031	chr16_69328241_-	ENSG00000213380.15	ENST00000306875.9	COG8-201	hsa-miR-6804-3p	chr16	69328235	69328242	8mer-1a	69328235	69328257	148	-16.47

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1097295

chr3_85385762_+

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-5688

chr16

69322671

69322677

7mer-m8

69322670

69322691

147

-12.65

ADediting_1337757

chr7_5495852_-

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-589-3p

chr16

69322464

69322470

7mer-m8

69322463

69322486

140

-11.8

ADediting_1535954

chr14_101045974_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-381-3p

chr16

69328707

69328714

8mer-1a

69328707

69328728

146

-17.37

ADediting_1535954

chr14_101045974_+

ENSG00000213380.15

ENST00000648169.1

COG8-207

hsa-miR-381-3p

chr16

69328707

69328714

8mer-1a

69328707

69328728

146

-17.37

ADediting_496066

chr15_66496985_-

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-4512

chr16

69327526

69327533

8mer-1a

69327526

69327546

154

-23.4

ADediting_843620

chr2_207754818_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-4775

chr16

69327641

69327648

8mer-1a

69327641

69327664

151

-12.07

ADediting_843620

chr2_207754818_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-4775

chr16

69328804

69328810

7mer-m8

69328803

69328824

157

-11.7

ADediting_843620

chr2_207754818_+

ENSG00000213380.15

ENST00000648169.1

COG8-207

hsa-miR-4775

chr16

69328804

69328810

7mer-m8

69328803

69328824

157

-11.7

ADediting_98288

chr1_32086990_+

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-5585-3p

chr16

69323281

69323287

7mer-m8

69323280

69323303

154

-23.94

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_107020

chr1_37500952_-

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-5581-3p

chr16

69322613

69322619

7mer-m8

69322612

69322633

151

-21.85

ADediting_1556067

chr19_40282625_-

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-641

chr16

69322348

69322354

7mer-m8

69322347

69322374

150

-12.51

ADediting_1596844

chr1_162342605_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-556-3p

chr16

69328679

69328686

8mer-1a

69328679

69328699

146

-10.52

ADediting_1596844

chr1_162342605_+

ENSG00000213380.15

ENST00000648169.1

COG8-207

hsa-miR-556-3p

chr16

69328679

69328686

8mer-1a

69328679

69328699

146

-10.52

ADediting_1631458

chr19_40282624_-

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-641

chr16

69322348

69322354

7mer-m8

69322347

69322374

150

-12.51

ADediting_291761

chr11_93733708_-

ENSG00000213380.15

ENST00000562595.5

COG8-203

hsa-miR-1304-3p

chr16

69323145

69323151

7mer-m8

69323144

69323166

153

-19.3

ADediting_527135

chr16_24203190_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-1273h-3p

chr16

69328735

69328741

7mer-m8

69328734

69328755

140

-18.89

ADediting_527135

chr16_24203190_+

ENSG00000213380.15

ENST00000648169.1

COG8-207

hsa-miR-1273h-3p

chr16

69328735

69328741

7mer-m8

69328734

69328755

140

-18.89

ADediting_843620

chr2_207754818_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-4775

chr16

69327059

69327065

7mer-m8

69327058

69327079

142

-8.86

ADediting_843620

chr2_207754818_+

ENSG00000213380.15

ENST00000306875.9

COG8-201

hsa-miR-4775

chr16

69327332

69327338

7mer-m8

69327331

69327353

153

-6.96

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for COG8

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000306875.9	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_560938	ENST00000306875.9	chr16_69327161_-	3999	-1645.50	-1644.20	-1753.30
ADediting_560939	ENST00000306875.9	chr16_69327197_-	3963	-1643.80	-1644.20	-1753.30
ADediting_560940	ENST00000306875.9	chr16_69327203_-	3957	-1643.50	-1644.20	-1753.30
ADediting_560941	ENST00000306875.9	chr16_69327233_-	3927	-1643.70	-1644.20	-1753.30
ADediting_560942	ENST00000306875.9	chr16_69327235_-	3925	-1646.70	-1644.20	-1753.30
ADediting_560943	ENST00000306875.9	chr16_69327244_-	3916	-1646.30	-1644.20	-1753.30
ADediting_560944	ENST00000306875.9	chr16_69327253_-	3907	-1645.00	-1644.20	-1753.30
ADediting_560945	ENST00000306875.9	chr16_69327257_-	3903	-1646.50	-1644.20	-1753.30
ADediting_560946	ENST00000306875.9	chr16_69327264_-	3896	-1646.10	-1644.20	-1753.30
ADediting_560947	ENST00000306875.9	chr16_69327265_-	3895	-1645.50	-1644.20	-1753.30
ADediting_560948	ENST00000306875.9	chr16_69327266_-	3894	-1645.70	-1644.20	-1753.30
ADediting_560949	ENST00000306875.9	chr16_69327273_-	3887	-1644.20	-1644.20	-1753.30
ADediting_560950	ENST00000306875.9	chr16_69327296_-	3864	-1645.10	-1644.20	-1753.30
ADediting_560951	ENST00000306875.9	chr16_69327300_-	3860	-1644.90	-1644.20	-1753.30
ADediting_560952	ENST00000306875.9	chr16_69327302_-	3858	-1644.60	-1644.20	-1753.30
ADediting_560953	ENST00000306875.9	chr16_69327305_-	3855	-1647.20	-1644.20	-1753.30
ADediting_560954	ENST00000306875.9	chr16_69327306_-	3854	-1644.20	-1644.20	-1753.30
ADediting_560955	ENST00000306875.9	chr16_69327316_-	3844	-1648.30	-1644.20	-1753.30
ADediting_560956	ENST00000306875.9	chr16_69327332_-	3828	-1648.00	-1644.20	-1753.30
ADediting_560957	ENST00000306875.9	chr16_69327335_-	3825	-1644.20	-1644.20	-1753.30
ADediting_560958	ENST00000306875.9	chr16_69327336_-	3824	-1644.20	-1644.20	-1753.30
ADediting_560959	ENST00000306875.9	chr16_69327341_-	3819	-1644.20	-1644.20	-1753.30
ADediting_560960	ENST00000306875.9	chr16_69327343_-	3817	-1644.20	-1644.20	-1753.30
ADediting_560961	ENST00000306875.9	chr16_69327344_-	3816	-1644.20	-1644.20	-1753.30
ADediting_560962	ENST00000306875.9	chr16_69327345_-	3815	-1643.90	-1644.20	-1753.30
ADediting_560963	ENST00000306875.9	chr16_69327346_-	3814	-1644.30	-1644.20	-1753.30
ADediting_560964	ENST00000306875.9	chr16_69327347_-	3813	-1644.30	-1644.20	-1753.30
ADediting_560965	ENST00000306875.9	chr16_69327350_-	3810	-1645.10	-1644.20	-1753.30
ADediting_560966	ENST00000306875.9	chr16_69327361_-	3799	-1644.20	-1644.20	-1753.30
ADediting_1543865	ENST00000306875.9	chr16_69327362_-	3798	-1649.00	-1644.20	-1753.30
ADediting_560967	ENST00000306875.9	chr16_69327369_-	3791	-1644.20	-1644.20	-1753.30
ADediting_560968	ENST00000306875.9	chr16_69327371_-	3789	-1644.20	-1644.20	-1753.30
ADediting_560969	ENST00000306875.9	chr16_69327372_-	3788	-1645.20	-1644.20	-1753.30
ADediting_560970	ENST00000306875.9	chr16_69327386_-	3774	-1645.10	-1644.20	-1753.30
ADediting_560971	ENST00000306875.9	chr16_69327387_-	3773	-1646.40	-1644.20	-1753.30
ADediting_560972	ENST00000306875.9	chr16_69327392_-	3768	-1644.20	-1644.20	-1753.30
ADediting_560973	ENST00000306875.9	chr16_69327395_-	3765	-1645.10	-1644.20	-1753.30
ADediting_560974	ENST00000306875.9	chr16_69327400_-	3760	-1644.10	-1644.20	-1753.30
ADediting_560975	ENST00000306875.9	chr16_69327405_-	3755	-1646.90	-1644.20	-1753.30
ADediting_560976	ENST00000306875.9	chr16_69327410_-	3750	-1647.70	-1644.20	-1753.30
ADediting_560977	ENST00000306875.9	chr16_69327414_-	3746	-1643.50	-1644.20	-1753.30
ADediting_560978	ENST00000306875.9	chr16_69327418_-	3742	-1644.20	-1644.20	-1753.30
ADediting_560979	ENST00000306875.9	chr16_69327419_-	3741	-1649.30	-1644.20	-1753.30
ADediting_560980	ENST00000306875.9	chr16_69327435_-	3725	-1643.40	-1644.20	-1753.30
ADediting_560981	ENST00000306875.9	chr16_69327440_-	3720	-1644.20	-1644.20	-1753.30
ADediting_560982	ENST00000306875.9	chr16_69327441_-	3719	-1644.50	-1644.20	-1753.30
ADediting_560983	ENST00000306875.9	chr16_69327463_-	3697	-1647.20	-1644.20	-1753.30
ADediting_560984	ENST00000306875.9	chr16_69327755_-	3405	-1643.50	-1644.20	-1753.30
ADediting_560985	ENST00000306875.9	chr16_69327767_-	3393	-1643.90	-1644.20	-1753.30
ADediting_560986	ENST00000306875.9	chr16_69327768_-	3392	-1644.30	-1644.20	-1753.30
ADediting_560987	ENST00000306875.9	chr16_69327790_-	3370	-1644.50	-1644.20	-1753.30
ADediting_560988	ENST00000306875.9	chr16_69327791_-	3369	-1647.70	-1644.20	-1753.30
ADediting_560989	ENST00000306875.9	chr16_69327795_-	3365	-1647.20	-1644.20	-1753.30
ADediting_560990	ENST00000306875.9	chr16_69327809_-	3351	-1647.20	-1644.20	-1753.30
ADediting_560991	ENST00000306875.9	chr16_69327820_-	3340	-1643.50	-1644.20	-1753.30
ADediting_560992	ENST00000306875.9	chr16_69327832_-	3328	-1648.60	-1644.20	-1753.30
ADediting_560993	ENST00000306875.9	chr16_69327843_-	3317	-1643.60	-1644.20	-1753.30
ADediting_560994	ENST00000306875.9	chr16_69327845_-	3315	-1643.30	-1644.20	-1753.30
ADediting_560995	ENST00000306875.9	chr16_69327847_-	3313	-1643.90	-1644.20	-1753.30
ADediting_560996	ENST00000306875.9	chr16_69327852_-	3308	-1645.90	-1644.20	-1753.30
ADediting_560997	ENST00000306875.9	chr16_69328011_-	3149	-1643.50	-1644.20	-1753.30
ADediting_560998	ENST00000306875.9	chr16_69328021_-	3139	-1646.00	-1644.20	-1753.30
ADediting_560999	ENST00000306875.9	chr16_69328025_-	3135	-1643.50	-1644.20	-1753.30
ADediting_561000	ENST00000306875.9	chr16_69328027_-	3133	-1648.60	-1644.20	-1753.30
ADediting_561001	ENST00000306875.9	chr16_69328041_-	3119	-1643.50	-1644.20	-1753.30
ADediting_561002	ENST00000306875.9	chr16_69328051_-	3109	-1646.60	-1644.20	-1753.30
ADediting_561003	ENST00000306875.9	chr16_69328054_-	3106	-1644.20	-1644.20	-1753.30
ADediting_561004	ENST00000306875.9	chr16_69328059_-	3101	-1643.40	-1644.20	-1753.30
ADediting_561005	ENST00000306875.9	chr16_69328063_-	3097	-1643.90	-1644.20	-1753.30
ADediting_561006	ENST00000306875.9	chr16_69328064_-	3096	-1643.90	-1644.20	-1753.30
ADediting_561007	ENST00000306875.9	chr16_69328068_-	3092	-1644.70	-1644.20	-1753.30
ADediting_561008	ENST00000306875.9	chr16_69328069_-	3091	-1644.10	-1644.20	-1753.30
ADediting_561009	ENST00000306875.9	chr16_69328076_-	3084	-1646.90	-1644.20	-1753.30
ADediting_561010	ENST00000306875.9	chr16_69328085_-	3075	-1645.80	-1644.20	-1753.30
ADediting_561011	ENST00000306875.9	chr16_69328092_-	3068	-1644.90	-1644.20	-1753.30
ADediting_561012	ENST00000306875.9	chr16_69328095_-	3065	-1646.10	-1644.20	-1753.30
ADediting_561013	ENST00000306875.9	chr16_69328112_-	3048	-1648.90	-1644.20	-1753.30
ADediting_561014	ENST00000306875.9	chr16_69328116_-	3044	-1644.70	-1644.20	-1753.30
ADediting_561015	ENST00000306875.9	chr16_69328118_-	3042	-1646.40	-1644.20	-1753.30
ADediting_561016	ENST00000306875.9	chr16_69328121_-	3039	-1644.20	-1644.20	-1753.30
ADediting_561017	ENST00000306875.9	chr16_69328125_-	3035	-1643.80	-1644.20	-1753.30
ADediting_561018	ENST00000306875.9	chr16_69328130_-	3030	-1644.30	-1644.20	-1753.30
ADediting_561019	ENST00000306875.9	chr16_69328141_-	3019	-1644.80	-1644.20	-1753.30
ADediting_561020	ENST00000306875.9	chr16_69328142_-	3018	-1649.20	-1644.20	-1753.30
ADediting_561021	ENST00000306875.9	chr16_69328151_-	3009	-1643.90	-1644.20	-1753.30
ADediting_561022	ENST00000306875.9	chr16_69328166_-	2994	-1647.20	-1644.20	-1753.30
ADediting_561023	ENST00000306875.9	chr16_69328167_-	2993	-1647.60	-1644.20	-1753.30
ADediting_561024	ENST00000306875.9	chr16_69328175_-	2985	-1643.50	-1644.20	-1753.30
ADediting_561025	ENST00000306875.9	chr16_69328183_-	2977	-1647.10	-1644.20	-1753.30
ADediting_561026	ENST00000306875.9	chr16_69328213_-	2947	-1643.50	-1644.20	-1753.30
ADediting_561027	ENST00000306875.9	chr16_69328218_-	2942	-1644.50	-1644.20	-1753.30
ADediting_561028	ENST00000306875.9	chr16_69328219_-	2941	-1645.40	-1644.20	-1753.30
ADediting_561029	ENST00000306875.9	chr16_69328227_-	2933	-1645.10	-1644.20	-1753.30
ADediting_561030	ENST00000306875.9	chr16_69328235_-	2925	-1644.30	-1644.20	-1753.30
ADediting_561031	ENST00000306875.9	chr16_69328241_-	2919	-1644.60	-1644.20	-1753.30

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for COG8

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
CER	ADediting_560944	chr16_69327253_-	0.00378930010101434	0.235036629276983	1.83356718763372e-06	0.378146148862932	0.870582937819711	0.0134138198242585
CER	ADediting_560950	chr16_69327296_-	0.00399629365328717	0.233715976204704	3.16669734518434e-07	0.403021720232835	0.382422782987407	0.0718248375731779
CER	ADediting_560953	chr16_69327305_-	0.00201057545883639	0.250256564158531	1.49611979442402e-06	0.381133796882095	0.133935465686421	0.122937119494226
CER	ADediting_560956	chr16_69327332_-	0.0297198886534846	0.177562834693954	0.000126681544171116	0.307887332119907	0.774215000308611	0.0236168007345593
CER	ADediting_560964	chr16_69327347_-	0.0137063092464811	0.200880331576586	4.28637396732124e-06	0.365341157238661	0.641954051841208	0.0382707537839736
CER	ADediting_560969	chr16_69327372_-	0.0153290255361328	0.197656879471468	1.52955804455531e-05	0.345064620185389	0.000364022649464917	0.287313003170061
CER	ADediting_560971	chr16_69327387_-	0.0246930705183766	0.183375059445855	3.48224778069039e-06	0.368525010177046	0.116411039148023	0.128734313919476
CER	ADediting_560976	chr16_69327410_-	0.00190677013875632	0.251488896308611	8.26598050330798e-10	0.474877239442625	0.021145886731908	0.188122507008052
CER	ADediting_560977	chr16_69327414_-	0.00278435118601714	0.242552964056957	4.05630399052462e-08	0.429774213974543	0.205059779392036	0.104061288289213
CER	ADediting_560978	chr16_69327418_-	0.0603614160093966	0.153723033740815	4.83465485019009e-05	0.325426953463573	0.0550643344740458	0.15697479888608
CER	ADediting_560988	chr16_69327791_-	0.00989266342122537	0.210022512714748	5.61085561920315e-05	0.322785651204201	0.407957532957218	0.0680554786311808
CER	ADediting_560990	chr16_69327809_-	0.0105552966252373	0.208233322916309	8.57216686635641e-05	0.315130414571946	0.13758118097736	0.121805285906024
DLPFC	ADediting_561045	chr16_69331790_-	0.00414936774057725	0.162384701403811	0.341209453969996	0.054236676477179	1.87964339655793e-16	0.444602552517015

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	3.52583171238252e-16	0.440941516423077	3.83697339010425e-06	0.258956291897921	6.63376167250135e-66	0.784589647807889
AC	3.20207392396963e-66	0.834782358941877	2.39784229017371e-38	0.701452549204727	2.64848588552634e-29	0.632179007801008
PCC	3.1685599747326e-44	0.802326842728132	1.52194407764041e-37	0.762208527378349	5.00385380991111e-10	0.430683456218441
CER	1.25109406865644e-37	0.81962175051706	3.77582578249041e-39	0.828793448920545	3.91540134124117e-07	0.400121324469937
TCX	1.76273863963386e-39	0.830719901100024	2.16087882791346e-08	0.437528988041549	1.37293520341599e-13	0.556802153245645
FP	8.58248109437301e-29	0.711684417486926	4.82624681285881e-25	0.675228652389201	1.71044860838805e-13	0.515894492888824
IFG	4.58188293234386e-08	0.856814740615107	2.5421241616292e-06	0.790786338714556	0.00160094838984457	0.597778008167972
STG	1.72528238737446e-18	0.78164448345677	4.38069309467204e-08	0.554680259383139	2.29889333250129e-05	0.44429734712989

Top

Relation with AD stages for COG8

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_560953	chr16_69327305_-	0.000414238765865092	0.333838571983415
CER	ADediting_560955	chr16_69327316_-	0.00073427676666815	0.320033999145983
CER	ADediting_560969	chr16_69327372_-	0.000307066476903832	0.340809627252186
CER	ADediting_560976	chr16_69327410_-	8.95452210946882e-06	0.412910622830851
CER	ADediting_560988	chr16_69327791_-	0.00151916800928363	0.301504279835203
TCX	ADediting_560959	chr16_69327341_-	0.00154812024728754	0.303763799138865
IFG	ADediting_561007	chr16_69328068_-	0.0354713369979928	0.422303326441651

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
CER	6.18268853385206e-07	0.458119717387373
TCX	1.06660762471314e-08	0.520555817510656

Top

RelatedDrugs for COG8

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for COG8

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
COG8	C0282577	Congenital Disorders of Glycosylation	3	GENOMICS_ENGLAND

Home

Download

Statistics

Landscape

Help

Contact

Gene summary for COG8

RNA A-to-I events for COG8

RNA editing positional annotations for COG8 using Annovar

RNA A-to-I editing events in the alternative splicing sites for COG8

Differntial gene expression between RNA A-to-I edited versus non-edited samples for COG8

Protein coding region RNA A-to-I editings for COG8

The effects of the RNA editing to the miRNA binding sites for COG8

The effects of the RNA editing to the stability of the RNA structures for COG8

Relation with ADAR for COG8

Relation with AD stages for COG8

RelatedDrugs for COG8

RelatedDiseases for COG8

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene