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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for NICN1 |
 Gene summary |
| Gene information | Gene symbol | NICN1 | Gene ID | 84276 |
| Gene name | nicolin 1 | |
| Synonyms | - | |
| Cytomap | 3p21.31 | |
| Type of gene | protein-coding | |
| Description | nicolin-1NPCEDRGPGs5tubulin polyglutamylase complex subunit 5 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9BSH3, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for NICN1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1075719(49423491, -), ADediting_1075720(49423494, -), ADediting_1075721(49423498, -), ADediting_1075722(49423500, -), ADediting_1075723(49423512, -), ADediting_1075724(49423513, -), ADediting_1075725(49423514, -), ADediting_1075726(49423535, -), ADediting_1075727(49423540, -), ADediting_1075728(49423545, -), ADediting_1075729(49423550, -), ADediting_1075730(49423552, -), ADediting_1075731(49423553, -), ADediting_1075732(49423554, -), ADediting_1075733(49423565, -), ADediting_1075734(49423589, -), ADediting_1075735(49423591, -), ADediting_1075736(49423594, -), ADediting_1075737(49423600, -), ADediting_1075738(49423607, -), ADediting_1075739(49423608, -), ADediting_1075740(49423624, -), ADediting_1075741(49423634, -), ADediting_1075742(49423644, -), ADediting_1075743(49423656, -), ADediting_1075744(49423669, -), ADediting_1075745(49423670, -), ADediting_1075746(49423673, -), ADediting_1075747(49423674, -), ADediting_1075748(49423680, -), ADediting_1075749(49423693, -), ADediting_1075750(49423709, -), ADediting_1075751(49423715, -), ADediting_1075752(49423730, -), ADediting_1075753(49423755, -), ADediting_1075754(49423878, -), ADediting_1075755(49423884, -), ADediting_1075756(49423886, -), ADediting_1075757(49423887, -), ADediting_1075758(49423889, -), ADediting_1075759(49423899, -), ADediting_1075760(49423904, -), ADediting_1075761(49423909, -), ADediting_1075762(49423914, -), ADediting_1075763(49423917, -), ADediting_1075764(49423938, -), ADediting_1075765(49423946, -), ADediting_1075766(49423947, -), ADediting_1075767(49423955, -), ADediting_1075768(49423956, -), ADediting_1075769(49423958, -), ADediting_1075770(49423961, -), ADediting_1075771(49423965, -), ADediting_1075772(49423971, -), ADediting_1075773(49423978, -), ADediting_1075774(49423982, -), ADediting_1075775(49423987, -), ADediting_1075776(49423988, -), ADediting_1075777(49424014, -), ADediting_1075778(49424017, -), ADediting_1075779(49424021, -), ADediting_1075780(49424024, -), ADediting_1075781(49424026, -), ADediting_1075782(49424028, -), ADediting_1075783(49424029, -), ADediting_1075784(49424030, -), ADediting_1075785(49424033, -), ADediting_1075786(49424044, -), ADediting_1075787(49424045, -), ADediting_1075788(49424048, -), ADediting_1075789(49424054, -), ADediting_1075790(49424055, -), ADediting_1075791(49424058, -), ADediting_1075792(49424064, -), ADediting_1075793(49424069, -), ADediting_1075794(49424070, -), ADediting_1075795(49424075, -), ADediting_1075796(49424078, -), ADediting_1075797(49424083, -), ADediting_1075798(49424088, -), ADediting_1075799(49424097, -), ADediting_1075800(49424101, -), ADediting_1075801(49424115, -), ADediting_1075802(49424118, -), ADediting_1075803(49424123, -), ADediting_1075804(49424124, -), ADediting_1075805(49424132, -), ADediting_1075806(49424140, -), ADediting_1075807(49424147, -), ADediting_1075808(49424390, -), ADediting_1075809(49426666, -), ADediting_1075810(49426776, -), ADediting_1574965(49424046, -), ADediting_1647870(49423994, -), |
Top |
RNA editing positional annotations for NICN1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1075719 | chr3_49423491_- | UTR3 |
| ADediting_1075720 | chr3_49423494_- | UTR3 |
| ADediting_1075721 | chr3_49423498_- | UTR3 |
| ADediting_1075722 | chr3_49423500_- | UTR3 |
| ADediting_1075723 | chr3_49423512_- | UTR3 |
| ADediting_1075724 | chr3_49423513_- | UTR3 |
| ADediting_1075725 | chr3_49423514_- | UTR3 |
| ADediting_1075726 | chr3_49423535_- | UTR3 |
| ADediting_1075727 | chr3_49423540_- | UTR3 |
| ADediting_1075728 | chr3_49423545_- | UTR3 |
| ADediting_1075729 | chr3_49423550_- | UTR3 |
| ADediting_1075730 | chr3_49423552_- | UTR3 |
| ADediting_1075731 | chr3_49423553_- | UTR3 |
| ADediting_1075732 | chr3_49423554_- | UTR3 |
| ADediting_1075733 | chr3_49423565_- | splicing |
| ADediting_1075734 | chr3_49423589_- | UTR3 |
| ADediting_1075735 | chr3_49423591_- | UTR3 |
| ADediting_1075736 | chr3_49423594_- | UTR3 |
| ADediting_1075737 | chr3_49423600_- | UTR3 |
| ADediting_1075738 | chr3_49423607_- | UTR3 |
| ADediting_1075739 | chr3_49423608_- | UTR3 |
| ADediting_1075740 | chr3_49423624_- | UTR3 |
| ADediting_1075741 | chr3_49423634_- | UTR3 |
| ADediting_1075742 | chr3_49423644_- | UTR3 |
| ADediting_1075743 | chr3_49423656_- | UTR3 |
| ADediting_1075744 | chr3_49423669_- | UTR3 |
| ADediting_1075745 | chr3_49423670_- | UTR3 |
| ADediting_1075746 | chr3_49423673_- | UTR3 |
| ADediting_1075747 | chr3_49423674_- | UTR3 |
| ADediting_1075748 | chr3_49423680_- | UTR3 |
| ADediting_1075749 | chr3_49423693_- | UTR3 |
| ADediting_1075750 | chr3_49423709_- | UTR3 |
| ADediting_1075751 | chr3_49423715_- | UTR3 |
| ADediting_1075752 | chr3_49423730_- | UTR3 |
| ADediting_1075753 | chr3_49423755_- | UTR3 |
| ADediting_1075754 | chr3_49423878_- | UTR3 |
| ADediting_1075755 | chr3_49423884_- | UTR3 |
| ADediting_1075756 | chr3_49423886_- | UTR3 |
| ADediting_1075757 | chr3_49423887_- | UTR3 |
| ADediting_1075758 | chr3_49423889_- | UTR3 |
| ADediting_1075759 | chr3_49423899_- | UTR3 |
| ADediting_1075760 | chr3_49423904_- | UTR3 |
| ADediting_1075761 | chr3_49423909_- | UTR3 |
| ADediting_1075762 | chr3_49423914_- | UTR3 |
| ADediting_1075763 | chr3_49423917_- | UTR3 |
| ADediting_1075764 | chr3_49423938_- | UTR3 |
| ADediting_1075765 | chr3_49423946_- | UTR3 |
| ADediting_1075766 | chr3_49423947_- | UTR3 |
| ADediting_1075767 | chr3_49423955_- | UTR3 |
| ADediting_1075768 | chr3_49423956_- | UTR3 |
| ADediting_1075769 | chr3_49423958_- | UTR3 |
| ADediting_1075770 | chr3_49423961_- | UTR3 |
| ADediting_1075771 | chr3_49423965_- | UTR3 |
| ADediting_1075772 | chr3_49423971_- | UTR3 |
| ADediting_1075773 | chr3_49423978_- | UTR3 |
| ADediting_1075774 | chr3_49423982_- | UTR3 |
| ADediting_1075775 | chr3_49423987_- | UTR3 |
| ADediting_1075776 | chr3_49423988_- | UTR3 |
| ADediting_1075777 | chr3_49424014_- | UTR3 |
| ADediting_1075778 | chr3_49424017_- | UTR3 |
| ADediting_1075779 | chr3_49424021_- | UTR3 |
| ADediting_1075780 | chr3_49424024_- | UTR3 |
| ADediting_1075781 | chr3_49424026_- | UTR3 |
| ADediting_1075782 | chr3_49424028_- | UTR3 |
| ADediting_1075783 | chr3_49424029_- | UTR3 |
| ADediting_1075784 | chr3_49424030_- | UTR3 |
| ADediting_1075785 | chr3_49424033_- | UTR3 |
| ADediting_1075786 | chr3_49424044_- | UTR3 |
| ADediting_1075787 | chr3_49424045_- | UTR3 |
| ADediting_1075788 | chr3_49424048_- | UTR3 |
| ADediting_1075789 | chr3_49424054_- | UTR3 |
| ADediting_1075790 | chr3_49424055_- | UTR3 |
| ADediting_1075791 | chr3_49424058_- | UTR3 |
| ADediting_1075792 | chr3_49424064_- | UTR3 |
| ADediting_1075793 | chr3_49424069_- | UTR3 |
| ADediting_1075794 | chr3_49424070_- | UTR3 |
| ADediting_1075795 | chr3_49424075_- | UTR3 |
| ADediting_1075796 | chr3_49424078_- | UTR3 |
| ADediting_1075797 | chr3_49424083_- | UTR3 |
| ADediting_1075798 | chr3_49424088_- | UTR3 |
| ADediting_1075799 | chr3_49424097_- | UTR3 |
| ADediting_1075800 | chr3_49424101_- | UTR3 |
| ADediting_1075801 | chr3_49424115_- | UTR3 |
| ADediting_1075802 | chr3_49424118_- | UTR3 |
| ADediting_1075803 | chr3_49424123_- | UTR3 |
| ADediting_1075804 | chr3_49424124_- | UTR3 |
| ADediting_1075805 | chr3_49424132_- | UTR3 |
| ADediting_1075806 | chr3_49424140_- | UTR3 |
| ADediting_1075807 | chr3_49424147_- | UTR3 |
| ADediting_1075808 | chr3_49424390_- | UTR3 |
| ADediting_1075809 | chr3_49426666_- | intronic |
| ADediting_1075810 | chr3_49426776_- | intronic |
| ADediting_1574965 | chr3_49424046_- | UTR3 |
| ADediting_1647870 | chr3_49423994_- | UTR3 |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1075719 | chr3_49423491_- | SINE | Alu | Name=AluSp |
| ADediting_1075720 | chr3_49423494_- | SINE | Alu | Name=AluSp |
| ADediting_1075721 | chr3_49423498_- | SINE | Alu | Name=AluSp |
| ADediting_1075722 | chr3_49423500_- | SINE | Alu | Name=AluSp |
| ADediting_1075723 | chr3_49423512_- | SINE | Alu | Name=AluSp |
| ADediting_1075724 | chr3_49423513_- | SINE | Alu | Name=AluSp |
| ADediting_1075725 | chr3_49423514_- | SINE | Alu | Name=AluSp |
| ADediting_1075726 | chr3_49423535_- | SINE | Alu | Name=AluSp |
| ADediting_1075727 | chr3_49423540_- | SINE | Alu | Name=AluSp |
| ADediting_1075728 | chr3_49423545_- | SINE | Alu | Name=AluSp |
| ADediting_1075729 | chr3_49423550_- | SINE | Alu | Name=AluSp |
| ADediting_1075730 | chr3_49423552_- | SINE | Alu | Name=AluSp |
| ADediting_1075731 | chr3_49423553_- | SINE | Alu | Name=AluSp |
| ADediting_1075732 | chr3_49423554_- | SINE | Alu | Name=AluSp |
| ADediting_1075733 | chr3_49423565_- | SINE | Alu | Name=AluSp |
| ADediting_1075734 | chr3_49423589_- | SINE | Alu | Name=AluSp |
| ADediting_1075735 | chr3_49423591_- | SINE | Alu | Name=AluSp |
| ADediting_1075736 | chr3_49423594_- | SINE | Alu | Name=AluSp |
| ADediting_1075737 | chr3_49423600_- | SINE | Alu | Name=AluSp |
| ADediting_1075738 | chr3_49423607_- | SINE | Alu | Name=AluSp |
| ADediting_1075739 | chr3_49423608_- | SINE | Alu | Name=AluSp |
| ADediting_1075740 | chr3_49423624_- | SINE | Alu | Name=AluSp |
| ADediting_1075741 | chr3_49423634_- | SINE | Alu | Name=AluSp |
| ADediting_1075742 | chr3_49423644_- | SINE | Alu | Name=AluSp |
| ADediting_1075743 | chr3_49423656_- | SINE | Alu | Name=AluSp |
| ADediting_1075744 | chr3_49423669_- | SINE | Alu | Name=AluSp |
| ADediting_1075745 | chr3_49423670_- | SINE | Alu | Name=AluSp |
| ADediting_1075746 | chr3_49423673_- | SINE | Alu | Name=AluSp |
| ADediting_1075747 | chr3_49423674_- | SINE | Alu | Name=AluSp |
| ADediting_1075748 | chr3_49423680_- | SINE | Alu | Name=AluSp |
| ADediting_1075749 | chr3_49423693_- | SINE | Alu | Name=AluSp |
| ADediting_1075750 | chr3_49423709_- | SINE | Alu | Name=AluSp |
| ADediting_1075751 | chr3_49423715_- | SINE | Alu | Name=AluSp |
| ADediting_1075752 | chr3_49423730_- | SINE | Alu | Name=AluSp |
| ADediting_1075753 | chr3_49423755_- | SINE | Alu | Name=AluSp |
| ADediting_1075754 | chr3_49423878_- | SINE | Alu | Name=AluSp |
| ADediting_1075755 | chr3_49423884_- | SINE | Alu | Name=AluSp |
| ADediting_1075756 | chr3_49423886_- | SINE | Alu | Name=AluSp |
| ADediting_1075757 | chr3_49423887_- | SINE | Alu | Name=AluSp |
| ADediting_1075758 | chr3_49423889_- | SINE | Alu | Name=AluSp |
| ADediting_1075759 | chr3_49423899_- | SINE | Alu | Name=AluSp |
| ADediting_1075760 | chr3_49423904_- | SINE | Alu | Name=AluSp |
| ADediting_1075761 | chr3_49423909_- | SINE | Alu | Name=AluSp |
| ADediting_1075762 | chr3_49423914_- | SINE | Alu | Name=AluSp |
| ADediting_1075763 | chr3_49423917_- | SINE | Alu | Name=AluSp |
| ADediting_1075764 | chr3_49423938_- | SINE | Alu | Name=AluSp |
| ADediting_1075765 | chr3_49423946_- | SINE | Alu | Name=AluSp |
| ADediting_1075766 | chr3_49423947_- | SINE | Alu | Name=AluSp |
| ADediting_1075767 | chr3_49423955_- | SINE | Alu | Name=AluSp |
| ADediting_1075768 | chr3_49423956_- | SINE | Alu | Name=AluSp |
| ADediting_1075769 | chr3_49423958_- | SINE | Alu | Name=AluSp |
| ADediting_1075770 | chr3_49423961_- | SINE | Alu | Name=AluSp |
| ADediting_1075771 | chr3_49423965_- | SINE | Alu | Name=AluSp |
| ADediting_1075772 | chr3_49423971_- | SINE | Alu | Name=AluSp |
| ADediting_1075773 | chr3_49423978_- | SINE | Alu | Name=AluSp |
| ADediting_1075774 | chr3_49423982_- | SINE | Alu | Name=AluSp |
| ADediting_1075775 | chr3_49423987_- | SINE | Alu | Name=AluSp |
| ADediting_1075776 | chr3_49423988_- | SINE | Alu | Name=AluSp |
| ADediting_1075777 | chr3_49424014_- | SINE | Alu | Name=AluSp |
| ADediting_1075778 | chr3_49424017_- | SINE | Alu | Name=AluSp |
| ADediting_1075779 | chr3_49424021_- | SINE | Alu | Name=AluSp |
| ADediting_1075780 | chr3_49424024_- | SINE | Alu | Name=AluSp |
| ADediting_1075781 | chr3_49424026_- | SINE | Alu | Name=AluSp |
| ADediting_1075782 | chr3_49424028_- | SINE | Alu | Name=AluSp |
| ADediting_1075783 | chr3_49424029_- | SINE | Alu | Name=AluSp |
| ADediting_1075784 | chr3_49424030_- | SINE | Alu | Name=AluSp |
| ADediting_1075785 | chr3_49424033_- | SINE | Alu | Name=AluSp |
| ADediting_1075786 | chr3_49424044_- | SINE | Alu | Name=AluSp |
| ADediting_1075787 | chr3_49424045_- | SINE | Alu | Name=AluSp |
| ADediting_1075788 | chr3_49424048_- | SINE | Alu | Name=AluSp |
| ADediting_1075789 | chr3_49424054_- | SINE | Alu | Name=AluSp |
| ADediting_1075790 | chr3_49424055_- | SINE | Alu | Name=AluSp |
| ADediting_1075791 | chr3_49424058_- | SINE | Alu | Name=AluSp |
| ADediting_1075792 | chr3_49424064_- | SINE | Alu | Name=AluSp |
| ADediting_1075793 | chr3_49424069_- | SINE | Alu | Name=AluSp |
| ADediting_1075794 | chr3_49424070_- | SINE | Alu | Name=AluSp |
| ADediting_1075795 | chr3_49424075_- | SINE | Alu | Name=AluSp |
| ADediting_1075796 | chr3_49424078_- | SINE | Alu | Name=AluSp |
| ADediting_1075797 | chr3_49424083_- | SINE | Alu | Name=AluSp |
| ADediting_1075798 | chr3_49424088_- | SINE | Alu | Name=AluSp |
| ADediting_1075799 | chr3_49424097_- | SINE | Alu | Name=AluSp |
| ADediting_1075800 | chr3_49424101_- | SINE | Alu | Name=AluSp |
| ADediting_1075801 | chr3_49424115_- | SINE | Alu | Name=AluSp |
| ADediting_1075802 | chr3_49424118_- | SINE | Alu | Name=AluSp |
| ADediting_1075803 | chr3_49424123_- | SINE | Alu | Name=AluSp |
| ADediting_1075804 | chr3_49424124_- | SINE | Alu | Name=AluSp |
| ADediting_1075805 | chr3_49424132_- | SINE | Alu | Name=AluSp |
| ADediting_1075806 | chr3_49424140_- | SINE | Alu | Name=AluSp |
| ADediting_1075807 | chr3_49424147_- | SINE | Alu | Name=AluSp |
| ADediting_1075809 | chr3_49426666_- | SINE | Alu | Name=AluSx |
| ADediting_1075810 | chr3_49426776_- | SINE | Alu | Name=AluSx |
| ADediting_1574965 | chr3_49424046_- | SINE | Alu | Name=AluSp |
| ADediting_1647870 | chr3_49423994_- | SINE | Alu | Name=AluSp |
Top |
RNA A-to-I editing events in the alternative splicing sites for NICN1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for NICN1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |