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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for PSD2 |
 Gene summary |
| Gene information | Gene symbol | PSD2 | Gene ID | 84249 |
| Gene name | pleckstrin and Sec7 domain containing 2 | |
| Synonyms | EFA6C | |
| Cytomap | 5q31.2 | |
| Type of gene | protein-coding | |
| Description | PH and SEC7 domain-containing protein 2exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 Cexchange factor for ARF6 Cpleckstrin homology and SEC7 domain-containing protein 2 | |
| Modification date | 20200313 | |
| UniProtAcc | Q9BQI7, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for PSD2 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1173962(139800483, +), ADediting_1173963(139800484, +), ADediting_1173964(139800497, +), ADediting_1173965(139800555, +), ADediting_1173966(139800557, +), ADediting_1173967(139800943, +), ADediting_1173968(139807987, +), ADediting_1173969(139813570, +), ADediting_1173970(139818283, +), ADediting_1173971(139818319, +), ADediting_1173972(139818349, +), ADediting_1173973(139818363, +), ADediting_1173974(139818387, +), ADediting_1173975(139818399, +), ADediting_1173976(139818407, +), ADediting_1173977(139818425, +), ADediting_1173978(139818461, +), ADediting_1173979(139818466, +), ADediting_1173980(139818485, +), ADediting_1173981(139818490, +), ADediting_1173982(139821012, +), ADediting_1173983(139821013, +), ADediting_1173984(139821033, +), ADediting_1173985(139821072, +), ADediting_1579424(139818380, +), |
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RNA editing positional annotations for PSD2 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_1173969 | chr5_139813570_+ | synonymous SNV | ENST00000274710.4 | c.A633G | p.A211A | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1173962 | chr5_139800483_+ | intronic |
| ADediting_1173963 | chr5_139800484_+ | intronic |
| ADediting_1173964 | chr5_139800497_+ | intronic |
| ADediting_1173965 | chr5_139800555_+ | intronic |
| ADediting_1173966 | chr5_139800557_+ | intronic |
| ADediting_1173967 | chr5_139800943_+ | intronic |
| ADediting_1173968 | chr5_139807987_+ | intronic |
| ADediting_1173969 | chr5_139813570_+ | exonic |
| ADediting_1173970 | chr5_139818283_+ | intronic |
| ADediting_1173971 | chr5_139818319_+ | intronic |
| ADediting_1173972 | chr5_139818349_+ | intronic |
| ADediting_1173973 | chr5_139818363_+ | intronic |
| ADediting_1173974 | chr5_139818387_+ | intronic |
| ADediting_1173975 | chr5_139818399_+ | intronic |
| ADediting_1173976 | chr5_139818407_+ | intronic |
| ADediting_1173977 | chr5_139818425_+ | intronic |
| ADediting_1173978 | chr5_139818461_+ | intronic |
| ADediting_1173979 | chr5_139818466_+ | intronic |
| ADediting_1173980 | chr5_139818485_+ | intronic |
| ADediting_1173981 | chr5_139818490_+ | intronic |
| ADediting_1173982 | chr5_139821012_+ | intronic |
| ADediting_1173983 | chr5_139821013_+ | intronic |
| ADediting_1173984 | chr5_139821033_+ | intronic |
| ADediting_1173985 | chr5_139821072_+ | intronic |
| ADediting_1579424 | chr5_139818380_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1173962 | chr5_139800483_+ | SINE | Alu | Name=AluSz |
| ADediting_1173963 | chr5_139800484_+ | SINE | Alu | Name=AluSz |
| ADediting_1173964 | chr5_139800497_+ | SINE | Alu | Name=AluSz |
| ADediting_1173965 | chr5_139800555_+ | SINE | Alu | Name=AluSz |
| ADediting_1173966 | chr5_139800557_+ | SINE | Alu | Name=AluSz |
| ADediting_1173967 | chr5_139800943_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1173970 | chr5_139818283_+ | SINE | Alu | Name=AluJb |
| ADediting_1173971 | chr5_139818319_+ | SINE | Alu | Name=AluJb |
| ADediting_1173972 | chr5_139818349_+ | SINE | Alu | Name=AluJb |
| ADediting_1173973 | chr5_139818363_+ | SINE | Alu | Name=AluJb |
| ADediting_1173974 | chr5_139818387_+ | SINE | Alu | Name=AluJb |
| ADediting_1173975 | chr5_139818399_+ | SINE | Alu | Name=AluJb |
| ADediting_1173976 | chr5_139818407_+ | SINE | Alu | Name=AluJb |
| ADediting_1173977 | chr5_139818425_+ | SINE | Alu | Name=AluJb |
| ADediting_1173978 | chr5_139818461_+ | SINE | Alu | Name=AluJb |
| ADediting_1173979 | chr5_139818466_+ | SINE | Alu | Name=AluJb |
| ADediting_1173980 | chr5_139818485_+ | SINE | Alu | Name=AluJb |
| ADediting_1173981 | chr5_139818490_+ | SINE | Alu | Name=AluJb |
| ADediting_1173982 | chr5_139821012_+ | SINE | Alu | Name=AluSx |
| ADediting_1173983 | chr5_139821013_+ | SINE | Alu | Name=AluSx |
| ADediting_1173984 | chr5_139821033_+ | SINE | Alu | Name=AluSx |
| ADediting_1173985 | chr5_139821072_+ | SINE | Alu | Name=AluSx |
| ADediting_1579424 | chr5_139818380_+ | SINE | Alu | Name=AluJb |
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RNA A-to-I editing events in the alternative splicing sites for PSD2 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PSD2 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |