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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ATP13A4 |
 Gene summary |
| Gene information | Gene symbol | ATP13A4 | Gene ID | 84239 |
| Gene name | ATPase 13A4 | |
| Synonyms | - | |
| Cytomap | 3q29 | |
| Type of gene | protein-coding | |
| Description | probable cation-transporting ATPase 13A4ATPase type 13A4P5-ATPasecation-transporting P5-ATPase | |
| Modification date | 20200320 | |
| UniProtAcc | Q4VNC1, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for ATP13A4 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1048096(193399604, -), ADediting_1048097(193399659, -), ADediting_1048098(193399681, -), ADediting_1048099(193399815, -), ADediting_1048100(193436477, -), ADediting_1048101(193436478, -), ADediting_1048102(193436481, -), ADediting_1048103(193436510, -), ADediting_1048104(193436520, -), ADediting_1048105(193436533, -), ADediting_1048106(193436537, -), ADediting_1048107(193436544, -), ADediting_1048108(193436545, -), ADediting_1048109(193436572, -), ADediting_1048110(193436576, -), ADediting_1048111(193436580, -), ADediting_1048112(193436612, -), ADediting_1048113(193436615, -), ADediting_1048114(193436625, -), ADediting_1048115(193436645, -), ADediting_1048116(193436655, -), ADediting_1048117(193436656, -), ADediting_1048118(193436679, -), ADediting_1048119(193436718, -), ADediting_1048120(193436719, -), ADediting_1048121(193436724, -), ADediting_1048122(193436725, -), ADediting_1048123(193436848, -), ADediting_1048124(193436860, -), ADediting_1048125(193436915, -), ADediting_1048126(193437980, -), ADediting_1048127(193437983, -), ADediting_1048128(193437996, -), ADediting_1048129(193438007, -), ADediting_1048130(193539038, -), ADediting_1048131(193539076, -), ADediting_1048132(193549570, -), ADediting_1048133(193549604, -), ADediting_1048134(193549627, -), ADediting_1048135(193549785, -), ADediting_1048136(193550439, -), ADediting_1048137(193550445, -), ADediting_1048138(193550505, -), ADediting_1048139(193550548, -), ADediting_1048140(193550578, -), ADediting_1048141(193550586, -), ADediting_1048142(193550587, -), ADediting_1048143(193551291, -), ADediting_1048144(193552112, -), ADediting_1048145(193552138, -), ADediting_1573244(193399644, -), ADediting_1573245(193436684, -), ADediting_1646522(193399684, -), ADediting_1646523(193459575, -), |
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RNA editing positional annotations for ATP13A4 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1048096 | chr3_193399604_- | UTR3 |
| ADediting_1048097 | chr3_193399659_- | UTR3 |
| ADediting_1048098 | chr3_193399681_- | UTR3 |
| ADediting_1048099 | chr3_193399815_- | UTR3 |
| ADediting_1048100 | chr3_193436477_- | intronic |
| ADediting_1048101 | chr3_193436478_- | intronic |
| ADediting_1048102 | chr3_193436481_- | intronic |
| ADediting_1048103 | chr3_193436510_- | intronic |
| ADediting_1048104 | chr3_193436520_- | intronic |
| ADediting_1048105 | chr3_193436533_- | intronic |
| ADediting_1048106 | chr3_193436537_- | intronic |
| ADediting_1048107 | chr3_193436544_- | intronic |
| ADediting_1048108 | chr3_193436545_- | intronic |
| ADediting_1048109 | chr3_193436572_- | intronic |
| ADediting_1048110 | chr3_193436576_- | intronic |
| ADediting_1048111 | chr3_193436580_- | intronic |
| ADediting_1048112 | chr3_193436612_- | intronic |
| ADediting_1048113 | chr3_193436615_- | intronic |
| ADediting_1048114 | chr3_193436625_- | intronic |
| ADediting_1048115 | chr3_193436645_- | intronic |
| ADediting_1048116 | chr3_193436655_- | intronic |
| ADediting_1048117 | chr3_193436656_- | intronic |
| ADediting_1048118 | chr3_193436679_- | intronic |
| ADediting_1048119 | chr3_193436718_- | intronic |
| ADediting_1048120 | chr3_193436719_- | intronic |
| ADediting_1048121 | chr3_193436724_- | intronic |
| ADediting_1048122 | chr3_193436725_- | intronic |
| ADediting_1048123 | chr3_193436848_- | intronic |
| ADediting_1048124 | chr3_193436860_- | intronic |
| ADediting_1048125 | chr3_193436915_- | intronic |
| ADediting_1048126 | chr3_193437980_- | intronic |
| ADediting_1048127 | chr3_193437983_- | intronic |
| ADediting_1048128 | chr3_193437996_- | intronic |
| ADediting_1048129 | chr3_193438007_- | intronic |
| ADediting_1048130 | chr3_193539038_- | intronic |
| ADediting_1048131 | chr3_193539076_- | intronic |
| ADediting_1048132 | chr3_193549570_- | intronic |
| ADediting_1048133 | chr3_193549604_- | intronic |
| ADediting_1048134 | chr3_193549627_- | intronic |
| ADediting_1048135 | chr3_193549785_- | intronic |
| ADediting_1048136 | chr3_193550439_- | intronic |
| ADediting_1048137 | chr3_193550445_- | intronic |
| ADediting_1048138 | chr3_193550505_- | intronic |
| ADediting_1048139 | chr3_193550548_- | intronic |
| ADediting_1048140 | chr3_193550578_- | intronic |
| ADediting_1048141 | chr3_193550586_- | intronic |
| ADediting_1048142 | chr3_193550587_- | intronic |
| ADediting_1048143 | chr3_193551291_- | intronic |
| ADediting_1048144 | chr3_193552112_- | intronic |
| ADediting_1048145 | chr3_193552138_- | intronic |
| ADediting_1573244 | chr3_193399644_- | UTR3 |
| ADediting_1573245 | chr3_193436684_- | intronic |
| ADediting_1646522 | chr3_193399684_- | UTR3 |
| ADediting_1646523 | chr3_193459575_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1048096 | chr3_193399604_- | SINE | Alu | Name=AluY |
| ADediting_1048097 | chr3_193399659_- | SINE | Alu | Name=AluY |
| ADediting_1048098 | chr3_193399681_- | SINE | Alu | Name=AluY |
| ADediting_1048099 | chr3_193399815_- | SINE | Alu | Name=AluY |
| ADediting_1048100 | chr3_193436477_- | SINE | Alu | Name=AluSz |
| ADediting_1048101 | chr3_193436478_- | SINE | Alu | Name=AluSz |
| ADediting_1048102 | chr3_193436481_- | SINE | Alu | Name=AluSz |
| ADediting_1048103 | chr3_193436510_- | SINE | Alu | Name=AluSz |
| ADediting_1048104 | chr3_193436520_- | SINE | Alu | Name=AluSz |
| ADediting_1048105 | chr3_193436533_- | SINE | Alu | Name=AluSz |
| ADediting_1048106 | chr3_193436537_- | SINE | Alu | Name=AluSz |
| ADediting_1048107 | chr3_193436544_- | SINE | Alu | Name=AluSz |
| ADediting_1048108 | chr3_193436545_- | SINE | Alu | Name=AluSz |
| ADediting_1048109 | chr3_193436572_- | SINE | Alu | Name=AluSz |
| ADediting_1048110 | chr3_193436576_- | SINE | Alu | Name=AluSz |
| ADediting_1048111 | chr3_193436580_- | SINE | Alu | Name=AluSz |
| ADediting_1048112 | chr3_193436612_- | SINE | Alu | Name=AluSz |
| ADediting_1048113 | chr3_193436615_- | SINE | Alu | Name=AluSz |
| ADediting_1048114 | chr3_193436625_- | SINE | Alu | Name=AluSz |
| ADediting_1048115 | chr3_193436645_- | SINE | Alu | Name=AluSz |
| ADediting_1048116 | chr3_193436655_- | SINE | Alu | Name=AluSz |
| ADediting_1048117 | chr3_193436656_- | SINE | Alu | Name=AluSz |
| ADediting_1048118 | chr3_193436679_- | SINE | Alu | Name=AluSz |
| ADediting_1048119 | chr3_193436718_- | SINE | Alu | Name=AluSz |
| ADediting_1048120 | chr3_193436719_- | SINE | Alu | Name=AluSz |
| ADediting_1048121 | chr3_193436724_- | SINE | Alu | Name=AluSz |
| ADediting_1048122 | chr3_193436725_- | SINE | Alu | Name=AluSz |
| ADediting_1048123 | chr3_193436848_- | SINE | Alu | Name=AluYa5 |
| ADediting_1048124 | chr3_193436860_- | SINE | Alu | Name=AluYa5 |
| ADediting_1048125 | chr3_193436915_- | SINE | Alu | Name=AluYa5 |
| ADediting_1048126 | chr3_193437980_- | SINE | Alu | Name=AluY |
| ADediting_1048127 | chr3_193437983_- | SINE | Alu | Name=AluY |
| ADediting_1048128 | chr3_193437996_- | SINE | Alu | Name=AluY |
| ADediting_1048129 | chr3_193438007_- | SINE | Alu | Name=AluY |
| ADediting_1048130 | chr3_193539038_- | SINE | Alu | Name=AluSp |
| ADediting_1048131 | chr3_193539076_- | SINE | Alu | Name=AluSp |
| ADediting_1048132 | chr3_193549570_- | SINE | Alu | Name=AluJb |
| ADediting_1048133 | chr3_193549604_- | SINE | Alu | Name=AluJb |
| ADediting_1048134 | chr3_193549627_- | SINE | Alu | Name=AluJb |
| ADediting_1048135 | chr3_193549785_- | SINE | Alu | Name=AluJb |
| ADediting_1048136 | chr3_193550439_- | SINE | Alu | Name=AluJb |
| ADediting_1048137 | chr3_193550445_- | SINE | Alu | Name=AluJb |
| ADediting_1048138 | chr3_193550505_- | SINE | Alu | Name=AluJb |
| ADediting_1048139 | chr3_193550548_- | SINE | Alu | Name=AluJb |
| ADediting_1048140 | chr3_193550578_- | SINE | Alu | Name=AluJb |
| ADediting_1048141 | chr3_193550586_- | SINE | Alu | Name=AluJb |
| ADediting_1048142 | chr3_193550587_- | SINE | Alu | Name=AluJb |
| ADediting_1048143 | chr3_193551291_- | SINE | Alu | Name=AluSc8 |
| ADediting_1048144 | chr3_193552112_- | SINE | Alu | Name=AluSc |
| ADediting_1048145 | chr3_193552138_- | SINE | Alu | Name=AluSc |
| ADediting_1573244 | chr3_193399644_- | SINE | Alu | Name=AluY |
| ADediting_1573245 | chr3_193436684_- | SINE | Alu | Name=AluSz |
| ADediting_1646522 | chr3_193399684_- | SINE | Alu | Name=AluY |
| ADediting_1646523 | chr3_193459575_- | SINE | Alu | Name=AluSx1 |
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RNA A-to-I editing events in the alternative splicing sites for ATP13A4 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ATP13A4 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ATP13A4 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ATP13A4 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1048096 | chr3_193399604_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-3189-3p | chr3 | 193399603 | 193399609 | 7mer-m8 | 193399602 | 193399624 | 149 | -24.33 |
| ADediting_1048096 | chr3_193399604_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-6813-3p | chr3 | 193399602 | 193399608 | 7mer-m8 | 193399601 | 193399621 | 140 | -12.55 |
| ADediting_1048097 | chr3_193399659_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-3190-5p | chr3 | 193399654 | 193399660 | 7mer-m8 | 193399653 | 193399672 | 146 | -17.92 |
| ADediting_1048097 | chr3_193399659_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-548s | chr3 | 193399655 | 193399661 | 7mer-m8 | 193399654 | 193399675 | 143 | -11.76 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-508-5p | chr3 | 193399811 | 193399817 | 7mer-m8 | 193399810 | 193399834 | 152 | -24.47 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-6512-3p | chr3 | 193399813 | 193399819 | 7mer-m8 | 193399812 | 193399833 | 146 | -18.8 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-6720-5p | chr3 | 193399813 | 193399819 | 7mer-m8 | 193399812 | 193399834 | 151 | -22.61 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-6849-3p | chr3 | 193399813 | 193399820 | 8mer-1a | 193399813 | 193399833 | 150 | -18.09 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-766-3p | chr3 | 193399812 | 193399818 | 7mer-m8 | 193399811 | 193399836 | 147 | -23 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1048097 | chr3_193399659_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-664a-5p | chr3 | 193399654 | 193399660 | 7mer-m8 | 193399653 | 193399675 | 148 | -17.08 |
| ADediting_1048098 | chr3_193399681_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-3675-3p | chr3 | 193399676 | 193399682 | 7mer-m8 | 193399675 | 193399696 | 145 | -12.58 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-1251-5p | chr3 | 193399812 | 193399818 | 7mer-m8 | 193399811 | 193399833 | 150 | -17.83 |
| ADediting_1048099 | chr3_193399815_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-1287-3p | chr3 | 193399813 | 193399819 | 7mer-m8 | 193399812 | 193399833 | 148 | -19.97 |
| ADediting_1573244 | chr3_193399644_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-510-3p | chr3 | 193399643 | 193399649 | 7mer-m8 | 193399642 | 193399662 | 148 | -15.65 |
| ADediting_1573244 | chr3_193399644_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-5186 | chr3 | 193399639 | 193399645 | 7mer-m8 | 193399638 | 193399658 | 147 | -16.19 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535954 | chr14_101045974_+ | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-381-3p | chr3 | 193399175 | 193399181 | 7mer-m8 | 193399174 | 193399194 | 157 | -20.55 |
| ADediting_1556067 | chr19_40282625_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-641 | chr3 | 193399890 | 193399896 | 7mer-1a | 193399890 | 193399912 | 142 | -13.08 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-641 | chr3 | 193400883 | 193400889 | 7mer-m8 | 193400882 | 193400907 | 146 | -17.07 |
| ADediting_496066 | chr15_66496985_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-4512 | chr3 | 193401657 | 193401664 | 8mer-1a | 193401657 | 193401678 | 140 | -15.37 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-4775 | chr3 | 193398967 | 193398973 | 7mer-m8 | 193398967 | 193398987 | 145 | -7.12 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-4775 | chr3 | 193400102 | 193400108 | 7mer-m8 | 193400101 | 193400124 | 154 | -17.87 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-5585-3p | chr3 | 193401864 | 193401870 | 7mer-m8 | 193401863 | 193401883 | 143 | -13.03 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-589-3p | chr3 | 193401180 | 193401187 | 8mer-1a | 193401180 | 193401203 | 146 | -14.41 |
| ADediting_496066 | chr15_66496985_- | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-4512 | chr3 | 193400489 | 193400495 | 7mer-m8 | 193400488 | 193400509 | 140 | -14.41 |
| ADediting_98288 | chr1_32086990_+ | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-5585-3p | chr3 | 193399976 | 193399983 | 8mer-1a | 193399976 | 193399997 | 147 | -10.79 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000127249.15 | ENST00000342695.9 | ATP13A4-202 | hsa-miR-5585-3p | chr3 | 193399976 | 193399983 | 8mer-1a | 193399976 | 193399997 | 147 | -10.79 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ATP13A4 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000342695.9 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_1048096 | ENST00000342695.9 | chr3_193399604_- | 6735 | -2264.80 | -2261.60 | -2273.30 |
| ADediting_1573244 | ENST00000342695.9 | chr3_193399644_- | 6695 | -2264.80 | -2261.60 | -2273.30 |
| ADediting_1048097 | ENST00000342695.9 | chr3_193399659_- | 6680 | -2266.80 | -2261.60 | -2273.30 |
| ADediting_1048098 | ENST00000342695.9 | chr3_193399681_- | 6658 | -2261.30 | -2261.60 | -2273.30 |
| ADediting_1646522 | ENST00000342695.9 | chr3_193399684_- | 6655 | -2261.30 | -2261.60 | -2273.30 |
| ADediting_1048099 | ENST00000342695.9 | chr3_193399815_- | 6524 | -2265.40 | -2261.60 | -2273.30 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ATP13A4 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_1048101 | chr3_193436478_- | 0.00869851101192587 | 0.148785840771957 | 0.292054476854999 | 0.0600304237290182 | 1.56357091114956e-10 | 0.353094307768907 |
| DLPFC | ADediting_1048105 | chr3_193436533_- | 0.0120920535843697 | 0.142375349542562 | 0.844402790374349 | 0.0111919640349847 | 3.8259153274478e-11 | 0.363974663282814 |
| DLPFC | ADediting_1048107 | chr3_193436544_- | 0.0695908676851008 | 0.103201900933726 | 0.93907400360126 | -0.00435873404557291 | 5.09367512535837e-12 | 0.378878221303768 |
| DLPFC | ADediting_1048108 | chr3_193436545_- | 0.0285397850429525 | 0.124390555898095 | 0.805381398664016 | 0.0140500022630556 | 5.99220714447805e-13 | 0.393907994524579 |
| DLPFC | ADediting_1048119 | chr3_193436718_- | 0.00558534410578397 | 0.157049083475271 | 0.193103261096233 | 0.0741153021481989 | 8.9236066397496e-12 | 0.374809964448537 |
| DLPFC | ADediting_1048120 | chr3_193436719_- | 0.0121921747809803 | 0.142211723367721 | 0.28671589258786 | 0.0606974226115371 | 5.39770391082821e-10 | 0.343162385935309 |
| DLPFC | ADediting_1048121 | chr3_193436724_- | 0.0120376210333401 | 0.142464809668465 | 0.33139792885784 | 0.0553475380088305 | 7.74793183500295e-14 | 0.407594677720191 |
| DLPFC | ADediting_1048122 | chr3_193436725_- | 0.0327993464719481 | 0.121275318170956 | 0.541272120995939 | 0.0348264081494416 | 1.39449943802705e-12 | 0.388067268641045 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.27302562222669e-09 | 0.32575232819224 | 2.32772836659393e-05 | 0.237802874693681 | 4.19528800247759e-07 | 0.282642600231164 |
| AC | 3.98969408045898e-35 | 0.678870635464325 | 4.89836961110193e-20 | 0.536508094105019 | 3.16082639604682e-29 | 0.631504992967636 |
| PCC | 0.000255741906498471 | 0.261663778899043 | 0.0753248632161376 | 0.128994958793188 | 5.89269982553245e-13 | 0.490505087504572 |
| CER | 0.00075262434593268 | 0.272194437423982 | 0.85877056442738 | -0.0146504699380524 | 5.46491828612751e-07 | 0.395508163525455 |
| TCX | 0.000221964917688054 | 0.297146877869172 | 0.88904135395712 | -0.0114872638481165 | 0.000182499456452119 | 0.30094341025274 |
| FP | 5.50815712215348e-12 | 0.486923455246922 | 1.67353939323936e-10 | 0.45551025681907 | 4.11451889546478e-11 | 0.468808814982262 |
| IFG | 0.00474484896733296 | 0.546066378023391 | 0.0363348399629612 | 0.420526077094907 | 0.000873581385931721 | 0.623272046827919 |
| PG | 2.39433213237718e-21 | 0.622565369069179 | 1.11265454278935e-11 | 0.471405992488569 | 0.0888927750918321 | 0.12509580026913 |
| STG | 9.50222808526667e-05 | 0.412872161959494 | 0.00440989935203616 | 0.307695950841782 | 3.30108875562467e-05 | 0.43657450072673 |
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Relation with AD stages for ATP13A4 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| TCX | ADediting_1048109 | chr3_193436572_- | 0.000530444308067176 | 0.330929374286144 |
| TCX | ADediting_1048119 | chr3_193436718_- | 0.000755267177799683 | 0.322243102824061 |
| TCX | ADediting_1048120 | chr3_193436719_- | 0.000419580136188883 | 0.336555368116874 |
| TCX | ADediting_1048121 | chr3_193436724_- | 0.000188641290562654 | 0.354979091483412 |
| TCX | ADediting_1048122 | chr3_193436725_- | 0.00015798471614687 | 0.358918240423884 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 9.16371346772197e-08 | 0.490910680377523 |
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RelatedDrugs for ATP13A4 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ATP13A4 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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