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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for SNHG3

check button Gene summary
Gene informationGene symbol

SNHG3

Gene ID

8420

Gene namesmall nucleolar RNA host gene 3
SynonymsNCRNA00014|RNU17C|RNU17D|U17HG|U17HG-A|U17HG-AB
Cytomap

1p35.3

Type of genencRNA
DescriptionU17 small nucleolar RNA hostsmall nucleolar RNA host gene (non-protein coding) 3small nucleolar RNA host gene 3 (non-protein coding)
Modification date20200313
UniProtAcc

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SNHG3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_93241(28509322, +), ADediting_93242(28509335, +), ADediting_93243(28509341, +), ADediting_93244(28509359, +), ADediting_93245(28509367, +), ADediting_93246(28509368, +), ADediting_93247(28509371, +), ADediting_93248(28509381, +), ADediting_93249(28509383, +), ADediting_93250(28509391, +), ADediting_93251(28509397, +), ADediting_93252(28509399, +), ADediting_93253(28509416, +), ADediting_93254(28509422, +), ADediting_93255(28509425, +), ADediting_93256(28509427, +), ADediting_93257(28509432, +), ADediting_93258(28509439, +), ADediting_93259(28509444, +), ADediting_93260(28509451, +), ADediting_93261(28509486, +), ADediting_93262(28509491, +), ADediting_93263(28509501, +), ADediting_93264(28509513, +), ADediting_93265(28509515, +), ADediting_93266(28510360, +), ADediting_93267(28510376, +), ADediting_93268(28510382, +), ADediting_93269(28510383, +), ADediting_93270(28510388, +), ADediting_93271(28510395, +), ADediting_93272(28510400, +), ADediting_93273(28510405, +), ADediting_93274(28510437, +), ADediting_93275(28510446, +), ADediting_93276(28510447, +), ADediting_93277(28510461, +), ADediting_93278(28510462, +), ADediting_93279(28510463, +), ADediting_93280(28510464, +), ADediting_93281(28510465, +), ADediting_93282(28510467, +), ADediting_93283(28510470, +), ADediting_93284(28510471, +), ADediting_93285(28510474, +), ADediting_93286(28510475, +), ADediting_93287(28510482, +), ADediting_93288(28510513, +), ADediting_93289(28510525, +), ADediting_1519041(28509442, +), ADediting_1519042(28509781, +), ADediting_1519043(28510374, +), ADediting_1519044(28510423, +), ADediting_1600375(28509346, +),

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RNA editing positional annotations for SNHG3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_93241chr1_28509322_+ncRNA_exonic
ADediting_93242chr1_28509335_+ncRNA_exonic
ADediting_93243chr1_28509341_+ncRNA_exonic
ADediting_93244chr1_28509359_+ncRNA_exonic
ADediting_93245chr1_28509367_+ncRNA_exonic
ADediting_93246chr1_28509368_+ncRNA_exonic
ADediting_93247chr1_28509371_+ncRNA_exonic
ADediting_93248chr1_28509381_+ncRNA_exonic
ADediting_93249chr1_28509383_+ncRNA_exonic
ADediting_93250chr1_28509391_+ncRNA_exonic
ADediting_93251chr1_28509397_+ncRNA_exonic
ADediting_93252chr1_28509399_+ncRNA_exonic
ADediting_93253chr1_28509416_+ncRNA_exonic
ADediting_93254chr1_28509422_+ncRNA_exonic
ADediting_93255chr1_28509425_+ncRNA_exonic
ADediting_93256chr1_28509427_+ncRNA_exonic
ADediting_93257chr1_28509432_+ncRNA_exonic
ADediting_93258chr1_28509439_+ncRNA_exonic
ADediting_93259chr1_28509444_+ncRNA_exonic
ADediting_93260chr1_28509451_+ncRNA_exonic
ADediting_93261chr1_28509486_+ncRNA_exonic
ADediting_93262chr1_28509491_+ncRNA_exonic
ADediting_93263chr1_28509501_+ncRNA_exonic
ADediting_93264chr1_28509513_+ncRNA_exonic
ADediting_93265chr1_28509515_+ncRNA_exonic
ADediting_93266chr1_28510360_+ncRNA_exonic
ADediting_93267chr1_28510376_+ncRNA_exonic
ADediting_93268chr1_28510382_+ncRNA_exonic
ADediting_93269chr1_28510383_+ncRNA_exonic
ADediting_93270chr1_28510388_+ncRNA_exonic
ADediting_93271chr1_28510395_+ncRNA_exonic
ADediting_93272chr1_28510400_+ncRNA_exonic
ADediting_93273chr1_28510405_+ncRNA_exonic
ADediting_93274chr1_28510437_+ncRNA_exonic
ADediting_93275chr1_28510446_+ncRNA_exonic
ADediting_93276chr1_28510447_+ncRNA_exonic
ADediting_93277chr1_28510461_+ncRNA_exonic
ADediting_93278chr1_28510462_+ncRNA_exonic
ADediting_93279chr1_28510463_+ncRNA_exonic
ADediting_93280chr1_28510464_+ncRNA_exonic
ADediting_93281chr1_28510465_+ncRNA_exonic
ADediting_93282chr1_28510467_+ncRNA_exonic
ADediting_93283chr1_28510470_+ncRNA_exonic
ADediting_93284chr1_28510471_+ncRNA_exonic
ADediting_93285chr1_28510474_+ncRNA_exonic
ADediting_93286chr1_28510475_+ncRNA_exonic
ADediting_93287chr1_28510482_+ncRNA_exonic
ADediting_93288chr1_28510513_+ncRNA_exonic
ADediting_93289chr1_28510525_+ncRNA_exonic
ADediting_1519041chr1_28509442_+ncRNA_exonic
ADediting_1519042chr1_28509781_+ncRNA_exonic
ADediting_1519043chr1_28510374_+ncRNA_exonic
ADediting_1519044chr1_28510423_+ncRNA_exonic
ADediting_1600375chr1_28509346_+ncRNA_exonic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_93241chr1_28509322_+SINEAluName=AluSx3
ADediting_93242chr1_28509335_+SINEAluName=AluSx3
ADediting_93243chr1_28509341_+SINEAluName=AluSx3
ADediting_93244chr1_28509359_+SINEAluName=AluSx3
ADediting_93245chr1_28509367_+SINEAluName=AluSx3
ADediting_93246chr1_28509368_+SINEAluName=AluSx3
ADediting_93247chr1_28509371_+SINEAluName=AluSx3
ADediting_93248chr1_28509381_+SINEAluName=AluSx3
ADediting_93249chr1_28509383_+SINEAluName=AluSx3
ADediting_93250chr1_28509391_+SINEAluName=AluSx3
ADediting_93251chr1_28509397_+SINEAluName=AluSx3
ADediting_93252chr1_28509399_+SINEAluName=AluSx3
ADediting_93253chr1_28509416_+SINEAluName=AluSx3
ADediting_93254chr1_28509422_+SINEAluName=AluSx3
ADediting_93255chr1_28509425_+SINEAluName=AluSx3
ADediting_93256chr1_28509427_+SINEAluName=AluSx3
ADediting_93257chr1_28509432_+SINEAluName=AluSx3
ADediting_93258chr1_28509439_+SINEAluName=AluSx3
ADediting_93259chr1_28509444_+SINEAluName=AluSx3
ADediting_93260chr1_28509451_+SINEAluName=AluSx3
ADediting_93261chr1_28509486_+SINEAluName=AluSx3
ADediting_93262chr1_28509491_+SINEAluName=AluSx3
ADediting_93263chr1_28509501_+SINEAluName=AluSx3
ADediting_93264chr1_28509513_+SINEAluName=AluSx3
ADediting_93265chr1_28509515_+SINEAluName=AluSx3
ADediting_93266chr1_28510360_+SINEAluName=AluSc
ADediting_93267chr1_28510376_+SINEAluName=AluSc
ADediting_93268chr1_28510382_+SINEAluName=AluSc
ADediting_93269chr1_28510383_+SINEAluName=AluSc
ADediting_93270chr1_28510388_+SINEAluName=AluSc
ADediting_93271chr1_28510395_+SINEAluName=AluSc
ADediting_93272chr1_28510400_+SINEAluName=AluSc
ADediting_93273chr1_28510405_+SINEAluName=AluSc
ADediting_93274chr1_28510437_+SINEAluName=AluSc
ADediting_93275chr1_28510446_+SINEAluName=AluSc
ADediting_93276chr1_28510447_+SINEAluName=AluSc
ADediting_93277chr1_28510461_+SINEAluName=AluSc
ADediting_93278chr1_28510462_+SINEAluName=AluSc
ADediting_93279chr1_28510463_+SINEAluName=AluSc
ADediting_93280chr1_28510464_+SINEAluName=AluSc
ADediting_93281chr1_28510465_+SINEAluName=AluSc
ADediting_93282chr1_28510467_+SINEAluName=AluSc
ADediting_93283chr1_28510470_+SINEAluName=AluSc
ADediting_93284chr1_28510471_+SINEAluName=AluSc
ADediting_93285chr1_28510474_+SINEAluName=AluSc
ADediting_93286chr1_28510475_+SINEAluName=AluSc
ADediting_93287chr1_28510482_+SINEAluName=AluSc
ADediting_93288chr1_28510513_+SINEAluName=AluSc
ADediting_93289chr1_28510525_+SINEAluName=AluSc
ADediting_1519041chr1_28509442_+SINEAluName=AluSx3
ADediting_1519043chr1_28510374_+SINEAluName=AluSc
ADediting_1519044chr1_28510423_+SINEAluName=AluSc
ADediting_1600375chr1_28509346_+SINEAluName=AluSx3

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RNA A-to-I editing events in the alternative splicing sites for SNHG3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SNHG3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.
boxplot

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for SNHG3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SNHG3

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1519041chr1_28509442_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-433-5pchr128509437285094448mer-1a2850942128509444158-24.11
ADediting_1519042chr1_28509781_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4803chr128509777285097837mer-m82850976528509784151-13.57
ADediting_1600375chr1_28509346_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4485-5pchr128509340285093467mer-m82850933228509347140-18.63
ADediting_1600375chr1_28509346_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-589-5pchr128509345285093517mer-m82850933228509352152-20.87
ADediting_93241chr1_28509322_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-17-3pchr128509316285093227mer-m82850930028509323154-16.64
ADediting_93242chr1_28509335_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1247-3pchr128509331285093377mer-m82850931628509338148-23.78
ADediting_93244chr1_28509359_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6089chr128509358285093647mer-m82850934228509365164-39.99
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6771-5pchr128509362285093687mer-m82850935028509369160-34.33
ADediting_93247chr1_28509371_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3614-5pchr128509365285093717mer-m82850934928509372152-25.27
ADediting_93247chr1_28509371_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4691-3pchr128509369285093757mer-m82850934928509376150-21.56
ADediting_93248chr1_28509381_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-17-3pchr128509378285093847mer-m82850936328509385162-20.42
ADediting_93250chr1_28509391_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1227-3pchr128509389285093957mer-m82850937728509396146-13.18
ADediting_93250chr1_28509391_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3064-3pchr128509388285093947mer-m82850937428509395146-16.2
ADediting_93250chr1_28509391_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3085-5pchr128509390285093978mer-1a2850936928509397151-24.01
ADediting_93251chr1_28509397_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1250-5pchr128509391285093977mer-m82850937828509398150-21.5
ADediting_93251chr1_28509397_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4466chr128509395285094017mer-m82850938528509402143-22.71
ADediting_93251chr1_28509397_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4746-3pchr128509392285093998mer-1a2850937828509399149-23.76
ADediting_93251chr1_28509397_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-675-5pchr128509395285094017mer-m82850938028509402142-20.03
ADediting_93257chr1_28509432_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6771-3pchr128509431285094377mer-m82850941728509438158-18.1
ADediting_93258chr1_28509439_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-8074chr128509438285094447mer-m82850942328509445162-22.61
ADediting_93260chr1_28509451_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3940-3pchr128509449285094557mer-m82850943528509456140-22.76
ADediting_93261chr1_28509486_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4767chr128509481285094877mer-m82850946528509488142-17.99
ADediting_93261chr1_28509486_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6765-5pchr128509485285094917mer-m82850946528509492158-29.87
ADediting_93266chr1_28510360_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3940-3pchr128510358285103647mer-m82851034428510365144-15.48
ADediting_93267chr1_28510376_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1268achr128510373285103797mer-m82851036328510380141-22.15
ADediting_93267chr1_28510376_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1268bchr128510373285103797mer-m82851036128510380141-24
ADediting_93268chr1_28510382_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-638chr128510382285103887mer-1a2851036428510388155-35.53
ADediting_93270chr1_28510388_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-371a-3pchr128510387285103937mer-m82851037428510394146-18.07
ADediting_93273chr1_28510405_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4707-3pchr128510402285104087mer-m82851038828510409167-27.39
ADediting_93274chr1_28510437_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3190-5pchr128510431285104377mer-m82851041928510438145-16.08
ADediting_93275chr1_28510446_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1182chr128510445285104517mer-m82851043028510452142-17.48
ADediting_93275chr1_28510446_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1229-3pchr128510441285104477mer-m82851042428510448146-14.04
ADediting_93276chr1_28510447_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3158-3pchr128510445285104517mer-m82851042728510452154-23.07
ADediting_93276chr1_28510447_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-412-3pchr128510441285104477mer-m82851042628510448151-16.28
ADediting_93276chr1_28510447_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6754-3pchr128510441285104477mer-m82851042828510448154-18.35
ADediting_93277chr1_28510461_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-30a-3pchr128510458285104658mer-1a2851044128510465154-14.69
ADediting_93277chr1_28510461_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-30d-3pchr128510458285104658mer-1a2851044028510465155-17.38
ADediting_93277chr1_28510461_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-30e-3pchr128510458285104658mer-1a2851044128510465154-15.5
ADediting_93279chr1_28510463_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-630chr128510462285104698mer-1a2851044328510469155-19.51
ADediting_93282chr1_28510467_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-153-5pchr128510461285104677mer-m82851044828510468146-10.15
ADediting_93282chr1_28510467_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3680-3pchr128510465285104728mer-1a2851045028510472140-12.39
ADediting_93283chr1_28510470_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4742-3pchr128510464285104718mer-1a2851044928510471142-14.28
ADediting_93283chr1_28510470_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4778-5pchr128510467285104748mer-1a2851045328510474145-10.24
ADediting_93284chr1_28510471_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-643chr128510465285104728mer-1a2851045028510472151-19.17
ADediting_93288chr1_28510513_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-718chr128510510285105167mer-m82851049628510517148-19.3

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1519041chr1_28509442_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5583-3pchr128509440285094467mer-m82850942528509447147-8.07
ADediting_1519042chr1_28509781_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-340-5pchr128509775285097817mer-m82850976428509782148-6.88
ADediting_1519043chr1_28510374_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4455chr128510373285103797mer-m82851036428510380143-13.91
ADediting_1519043chr1_28510374_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6807-5pchr128510368285103747mer-m82851035328510375144-21.24
ADediting_1519044chr1_28510423_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3675-3pchr128510422285104287mer-m82851040828510429140-8.37
ADediting_1519044chr1_28510423_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4777-5pchr128510419285104257mer-m82851040428510426150-13.34
ADediting_1519044chr1_28510423_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-517-5pchr128510420285104278mer-1a2851040628510427150-19.02
ADediting_93241chr1_28509322_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-495-5pchr128509319285093257mer-m82850930528509326140-11.91
ADediting_93241chr1_28509322_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6516-5pchr128509316285093227mer-m82850929928509323154-15.09
ADediting_93242chr1_28509335_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3689a-3pchr128509329285093357mer-m82850931328509336151-26.49
ADediting_93242chr1_28509335_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-490-3pchr128509333285093397mer-m82850931828509340146-17.33
ADediting_93242chr1_28509335_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6779-5pchr128509329285093357mer-m82850931828509336148-23.8
ADediting_93242chr1_28509335_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6780a-5pchr128509329285093357mer-m82850931128509336148-25.99
ADediting_93243chr1_28509341_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6078chr128509339285093468mer-1a2850932828509346149-21.5
ADediting_93244chr1_28509359_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4478chr128509357285093637mer-m82850934928509364149-25.05
ADediting_93244chr1_28509359_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4649-3pchr128509354285093607mer-m82850934128509361140-16.88
ADediting_93244chr1_28509359_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-7160-5pchr128509355285093617mer-m82850934228509362146-22.47
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-12126chr128509364285093718mer-1a2850934828509371147-13.23
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-30b-3pchr128509361285093688mer-1a2850934728509368151-15.38
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3689a-3pchr128509361285093688mer-1a2850934828509368147-18.72
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3689b-3pchr128509361285093688mer-1a2850934828509368147-17.55
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3689cchr128509361285093688mer-1a2850934828509368147-17.55
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6779-5pchr128509361285093688mer-1a2850935028509368148-22.58
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6780a-5pchr128509361285093688mer-1a2850934528509368152-25.37
ADediting_93245chr1_28509367_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-887-5pchr128509362285093687mer-m82850935028509369143-19.73
ADediting_93246chr1_28509368_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-12126chr128509364285093718mer-1a2850934828509371147-13.23
ADediting_93246chr1_28509368_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-887-5pchr128509362285093687mer-m82850935028509369143-19.73
ADediting_93247chr1_28509371_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5690chr128509369285093757mer-m82850935628509376145-14.96
ADediting_93248chr1_28509381_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-20b-3pchr128509378285093847mer-m82850936328509385153-15.95
ADediting_93249chr1_28509383_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-20b-3pchr128509378285093847mer-m82850936328509385153-15.95
ADediting_93252chr1_28509399_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3934-5pchr128509397285094037mer-m82850938328509404150-23.83
ADediting_93255chr1_28509425_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3675-3pchr128509424285094307mer-m82850941028509431145-12.58
ADediting_93256chr1_28509427_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3675-3pchr128509424285094307mer-m82850941028509431145-12.58
ADediting_93257chr1_28509432_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6072chr128509428285094347mer-m82850941328509435151-15.6
ADediting_93257chr1_28509432_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6891-3pchr128509428285094347mer-m82850941528509435146-12.88
ADediting_93259chr1_28509444_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5583-3pchr128509440285094467mer-m82850942528509447147-8.07
ADediting_93260chr1_28509451_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3190-5pchr128509446285094527mer-m82850943528509453144-16.24
ADediting_93260chr1_28509451_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-548schr128509445285094517mer-m82850942628509452143-13.39
ADediting_93261chr1_28509486_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1228-5pchr128509480285094867mer-m82850946528509487146-27
ADediting_93261chr1_28509486_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-541-3pchr128509482285094887mer-m82850946328509489144-19.68
ADediting_93261chr1_28509486_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6134chr128509484285094918mer-1a2850947328509491154-21.28
ADediting_93261chr1_28509486_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-654-5pchr128509482285094887mer-m82850947128509489146-19.26
ADediting_93262chr1_28509491_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4478chr128509489285094957mer-m82850948028509496154-23.4
ADediting_93262chr1_28509491_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-485-5pchr128509490285094967mer-m82850947628509497145-17.12
ADediting_93262chr1_28509491_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6884-5pchr128509490285094967mer-m82850947628509497154-23.23
ADediting_93262chr1_28509491_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-7160-5pchr128509487285094937mer-m82850947628509494154-20.89
ADediting_93262chr1_28509491_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-7162-3pchr128509486285094927mer-m82850947528509493150-18.37
ADediting_93266chr1_28510360_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-3085-3pchr128510355285103617mer-m82851034128510362150-22.54
ADediting_93266chr1_28510360_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-647chr128510354285103607mer-m82851034028510361150-17.94
ADediting_93266chr1_28510360_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6504-5pchr128510355285103617mer-m82851034128510362154-21.73
ADediting_93267chr1_28510376_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4455chr128510373285103797mer-m82851036428510380143-13.91
ADediting_93269chr1_28510383_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5089-5pchr128510382285103887mer-m82851036728510389148-14.01
ADediting_93270chr1_28510388_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5089-5pchr128510382285103887mer-m82851036728510389148-14.01
ADediting_93270chr1_28510388_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-512-3pchr128510387285103937mer-m82851037328510394149-15.79
ADediting_93270chr1_28510388_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6506-5pchr128510383285103897mer-m82851036828510390140-15.04
ADediting_93273chr1_28510405_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4485-5pchr128510404285104118mer-1a2851039628510411150-21.76
ADediting_93273chr1_28510405_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4763-5pchr128510402285104087mer-m82851038828510409148-27.32
ADediting_93273chr1_28510405_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6747-3pchr128510401285104077mer-m82851038828510408151-19.46
ADediting_93274chr1_28510437_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-1306-3pchr128510433285104397mer-m82851042328510440146-16.24
ADediting_93276chr1_28510447_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6823-5pchr128510446285104527mer-m82851043328510453147-17.98
ADediting_93287chr1_28510482_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-6872-3pchr128510479285104857mer-m82851046628510486141-13.01
ADediting_93288chr1_28510513_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5001-3pchr128510509285105168mer-1a2851049028510516155-25.86
ADediting_93289chr1_28510525_+ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-23a-5pchr128510522285105287mer-m82851050928510529145-16.72

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-589-3pchr128509004285090107mer-m82850898828509011145-17.44
ADediting_1337757chr7_5495852_-ENSG00000242125.3ENST00000437681.1SNHG3-202hsa-miR-589-3pchr128509004285090107mer-m82850898828509011145-17.44
ADediting_286380chr11_79422188_-ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5579-3pchr128509084285090907mer-m82850906628509091149-16.35
ADediting_286380chr11_79422188_-ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-5579-3pchr128510145285101517mer-m82851012928510152156-19.35
ADediting_286380chr11_79422188_-ENSG00000242125.3ENST00000437681.1SNHG3-202hsa-miR-5579-3pchr128509084285090907mer-m82850906628509091149-16.35
ADediting_291761chr11_93733708_-ENSG00000242125.3ENST00000437681.1SNHG3-202hsa-miR-1304-3pchr128506619285066257mer-m82850660528506626140-14.46
ADediting_496066chr15_66496985_-ENSG00000242125.3ENST00000437681.1SNHG3-202hsa-miR-4512chr128507748285077547mer-m82850773428507755140-22.02

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000242125.3ENST00000437681.1SNHG3-202hsa-miR-5688chr128508130285081367mer-1a2850811628508136150-22.42
ADediting_1391023chr8_140732605_-ENSG00000242125.3ENST00000437681.1SNHG3-202hsa-miR-151a-3pchr128507222285072287mer-m82850720728507229141-14.85
ADediting_496066chr15_66496985_-ENSG00000242125.3ENST00000413987.1SNHG3-201hsa-miR-4512chr128509733285097397mer-m82850971928509740140-21.12

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network
Differentially expressed lncRNA-miRNA network
boxplot

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The effects of the RNA editing to the stability of the RNA structures for SNHG3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000413987.1lncRNASoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_93241ENST00000413987.1chr1_28509322_+631-811.90-811.90-877.30
ADediting_93242ENST00000413987.1chr1_28509335_+644-818.10-811.90-877.30
ADediting_93243ENST00000413987.1chr1_28509341_+650-814.50-811.90-877.30
ADediting_1600375ENST00000413987.1chr1_28509346_+655-811.40-811.90-877.30
ADediting_93244ENST00000413987.1chr1_28509359_+668-811.20-811.90-877.30
ADediting_93245ENST00000413987.1chr1_28509367_+676-811.50-811.90-877.30
ADediting_93246ENST00000413987.1chr1_28509368_+677-811.80-811.90-877.30
ADediting_93247ENST00000413987.1chr1_28509371_+680-812.90-811.90-877.30
ADediting_93248ENST00000413987.1chr1_28509381_+690-813.50-811.90-877.30
ADediting_93249ENST00000413987.1chr1_28509383_+692-812.10-811.90-877.30
ADediting_93250ENST00000413987.1chr1_28509391_+700-811.40-811.90-877.30
ADediting_93251ENST00000413987.1chr1_28509397_+706-811.50-811.90-877.30
ADediting_93252ENST00000413987.1chr1_28509399_+708-815.30-811.90-877.30
ADediting_93253ENST00000413987.1chr1_28509416_+725-811.90-811.90-877.30
ADediting_93254ENST00000413987.1chr1_28509422_+731-811.60-811.90-877.30
ADediting_93255ENST00000413987.1chr1_28509425_+734-811.60-811.90-877.30
ADediting_93256ENST00000413987.1chr1_28509427_+736-811.90-811.90-877.30
ADediting_93257ENST00000413987.1chr1_28509432_+741-818.50-811.90-877.30
ADediting_93258ENST00000413987.1chr1_28509439_+748-811.50-811.90-877.30
ADediting_1519041ENST00000413987.1chr1_28509442_+751-817.30-811.90-877.30
ADediting_93259ENST00000413987.1chr1_28509444_+753-817.40-811.90-877.30
ADediting_93260ENST00000413987.1chr1_28509451_+760-811.20-811.90-877.30
ADediting_93261ENST00000413987.1chr1_28509486_+795-815.80-811.90-877.30
ADediting_93262ENST00000413987.1chr1_28509491_+800-811.90-811.90-877.30
ADediting_93263ENST00000413987.1chr1_28509501_+810-811.60-811.90-877.30
ADediting_93264ENST00000413987.1chr1_28509513_+822-811.90-811.90-877.30
ADediting_93265ENST00000413987.1chr1_28509515_+824-818.10-811.90-877.30
ADediting_1519042ENST00000413987.1chr1_28509781_+1090-818.10-811.90-877.30
ADediting_93266ENST00000413987.1chr1_28510360_+1669-818.10-811.90-877.30
ADediting_1519043ENST00000413987.1chr1_28510374_+1683-811.50-811.90-877.30
ADediting_93267ENST00000413987.1chr1_28510376_+1685-811.20-811.90-877.30
ADediting_93268ENST00000413987.1chr1_28510382_+1691-812.00-811.90-877.30
ADediting_93269ENST00000413987.1chr1_28510383_+1692-811.90-811.90-877.30
ADediting_93270ENST00000413987.1chr1_28510388_+1697-811.20-811.90-877.30
ADediting_93271ENST00000413987.1chr1_28510395_+1704-811.90-811.90-877.30
ADediting_93272ENST00000413987.1chr1_28510400_+1709-818.30-811.90-877.30
ADediting_93273ENST00000413987.1chr1_28510405_+1714-816.60-811.90-877.30
ADediting_1519044ENST00000413987.1chr1_28510423_+1732-815.10-811.90-877.30
ADediting_93274ENST00000413987.1chr1_28510437_+1746-811.60-811.90-877.30
ADediting_93275ENST00000413987.1chr1_28510446_+1755-812.00-811.90-877.30
ADediting_93276ENST00000413987.1chr1_28510447_+1756-811.90-811.90-877.30
ADediting_93277ENST00000413987.1chr1_28510461_+1770-812.00-811.90-877.30
ADediting_93278ENST00000413987.1chr1_28510462_+1771-812.00-811.90-877.30
ADediting_93279ENST00000413987.1chr1_28510463_+1772-812.00-811.90-877.30
ADediting_93280ENST00000413987.1chr1_28510464_+1773-812.00-811.90-877.30
ADediting_93281ENST00000413987.1chr1_28510465_+1774-811.90-811.90-877.30
ADediting_93282ENST00000413987.1chr1_28510467_+1776-811.90-811.90-877.30
ADediting_93283ENST00000413987.1chr1_28510470_+1779-812.00-811.90-877.30
ADediting_93284ENST00000413987.1chr1_28510471_+1780-812.00-811.90-877.30
ADediting_93285ENST00000413987.1chr1_28510474_+1783-811.90-811.90-877.30
ADediting_93286ENST00000413987.1chr1_28510475_+1784-818.10-811.90-877.30
ADediting_93287ENST00000413987.1chr1_28510482_+1791-815.70-811.90-877.30
ADediting_93288ENST00000413987.1chr1_28510513_+1822-811.90-811.90-877.30
ADediting_93289ENST00000413987.1chr1_28510525_+1834-811.90-811.90-877.30

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Relation with ADAR for SNHG3

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_93242chr1_28509335_+0.01585636319094560.1966733718757678.88777547839999e-090.4481491625469530.01025942802980060.209019603629201
CERADediting_93253chr1_28509416_+0.0005109606069573770.2803611892223579.24653183333373e-120.5198900726464190.0008536741536354820.269482670288503
CERADediting_93254chr1_28509422_+0.00465448662580550.2298902623167874.92122692830922e-100.4804194113988960.0006587439497092070.275032322961226
CERADediting_93255chr1_28509425_+0.00313697671246870.2396714301443612.73408464173376e-100.4865834422972170.000604086708030540.276861195459328
IFGADediting_93255chr1_28509425_+0.2031650133000670.2634804832220230.03319557932497040.4271580502318550.07378276532912810.363847751857614
CERADediting_93257chr1_28509432_+0.0007777437685121630.2714904350807932.55689156741402e-110.5102595411298810.004231494191822230.232287988692575
CERADediting_93264chr1_28509513_+0.000581927361304540.2776464310995623.88192378861873e-110.5062171826703798.12761590583755e-050.316103721658803
CERADediting_93265chr1_28509515_+6.32383611681417e-070.3934663367471131.48601887769762e-120.5364731336378920.0002489383903546910.294898303691094
CERADediting_93276chr1_28510447_+0.1985545374558030.1055649064563296.67076764424598e-050.3196851191911470.03180704117155620.175393803329464

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC4.84857630398758e-120.3792333379174262.9759816880646e-090.3288761923397931.29119478238393e-270.56566034094171
AC7.85630669524654e-480.7574982912773991.40466256029044e-310.6514229239830431.12416038630606e-130.446876481422401
PCC2.28871111969231e-070.3638677828368467.09136704363627e-080.3778508143716730.004564450034322650.204395551380074
CER3.90648506383574e-060.3667675082281381.18265737551054e-130.5580309632357270.00117712118892690.262437880326521
TCX2.60577443144012e-050.3361389513116070.005245257083633780.2268493507913870.0001427396280570840.305636261176093
FP2.61466416943156e-110.4729867929747151.97754810309603e-150.5494836372329470.0137774201539920.184324745688446
IFG0.6223468436043150.1035408390998190.3371125114288320.2002760210727510.04264556715332440.408464259744504
PG3.17278441877604e-150.5360060595971867.52127055424634e-150.5297855024493280.3282137106082990.0720824017805825
STG0.0001646516373657220.3998125220014663.96547045156482e-050.4325879828397390.9318008936575350.00947929025666217

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Relation with AD stages for SNHG3

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
PCCADediting_93242chr1_28509335_+2.41558671774711e-050.300417170448911
CERADediting_93242chr1_28509335_+6.63861094028118e-050.374146342326473
CERADediting_93253chr1_28509416_+9.38183501297956e-050.366931432783528
CERADediting_93254chr1_28509422_+3.02027498656705e-070.469208290769287
CERADediting_93255chr1_28509425_+1.64710657147651e-050.401621648645593
CERADediting_93257chr1_28509432_+3.93184873917111e-070.465171064270788
CERADediting_93259chr1_28509444_+2.92173343022707e-050.390617754358343
CERADediting_93262chr1_28509491_+0.0001602111237647660.355420810884988
CERADediting_93264chr1_28509513_+5.72902433098312e-080.493524961500833
CERADediting_93265chr1_28509515_+1.5341670251263e-070.479344800655008

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER2.44368389672048e-080.505292951297533
TCX7.59671946653155e-050.374662678926405

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RelatedDrugs for SNHG3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SNHG3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource