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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for TSC22D4

check button Gene summary
Gene informationGene symbol

TSC22D4

Gene ID

81628

Gene nameTSC22 domain family member 4
SynonymsTHG-1|THG1|TILZ2
Cytomap

7q22.1

Type of geneprotein-coding
DescriptionTSC22 domain family protein 4TSC22-related-inducible leucine zipper protein 2tsc-22-like protein THG-1
Modification date20200313
UniProtAcc

Q9Y3Q8,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for TSC22D4

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1285594(100468493, -), ADediting_1285595(100468692, -), ADediting_1285596(100468734, -), ADediting_1285597(100468966, -), ADediting_1285598(100469000, -), ADediting_1285599(100469009, -), ADediting_1285600(100469014, -), ADediting_1285601(100469021, -), ADediting_1285602(100469022, -), ADediting_1285603(100469023, -), ADediting_1285604(100469043, -), ADediting_1285605(100469105, -), ADediting_1285606(100469111, -), ADediting_1285607(100469115, -), ADediting_1285608(100469144, -), ADediting_1285609(100469151, -), ADediting_1285610(100469296, -), ADediting_1285611(100469297, -), ADediting_1285612(100470358, -), ADediting_1285613(100470359, -), ADediting_1285614(100470368, -), ADediting_1285615(100470384, -), ADediting_1285616(100470394, -), ADediting_1285617(100470397, -), ADediting_1285618(100470407, -), ADediting_1285619(100470420, -), ADediting_1285620(100470424, -), ADediting_1285621(100470429, -), ADediting_1285622(100470430, -), ADediting_1285623(100470456, -), ADediting_1285624(100470465, -), ADediting_1285625(100470467, -), ADediting_1285626(100470493, -), ADediting_1285627(100470518, -), ADediting_1285628(100470523, -), ADediting_1285629(100470524, -), ADediting_1285630(100470532, -), ADediting_1285631(100470537, -), ADediting_1285632(100470578, -), ADediting_1285633(100470579, -), ADediting_1285634(100470585, -), ADediting_1285635(100470595, -), ADediting_1285636(100470706, -), ADediting_1285637(100471477, -), ADediting_1285638(100471480, -), ADediting_1285639(100471483, -), ADediting_1285640(100471495, -), ADediting_1285641(100471497, -), ADediting_1285642(100471510, -), ADediting_1285643(100471514, -), ADediting_1285644(100471535, -), ADediting_1285645(100471536, -), ADediting_1285646(100471537, -), ADediting_1285647(100471542, -), ADediting_1285648(100471548, -), ADediting_1285649(100471557, -), ADediting_1285650(100471560, -), ADediting_1285651(100471605, -), ADediting_1285652(100471616, -), ADediting_1285653(100471618, -), ADediting_1285654(100471628, -), ADediting_1285655(100471640, -), ADediting_1285656(100471657, -), ADediting_1285657(100471658, -), ADediting_1285658(100471664, -), ADediting_1285659(100471696, -), ADediting_1285660(100471702, -), ADediting_1285661(100471706, -), ADediting_1285662(100471713, -), ADediting_1285663(100471738, -), ADediting_1285664(100473502, -), ADediting_1285665(100473527, -), ADediting_1285666(100473534, -), ADediting_1285667(100473574, -), ADediting_1285668(100473579, -), ADediting_1285669(100473602, -), ADediting_1285670(100473618, -), ADediting_1285671(100473619, -), ADediting_1285672(100473620, -), ADediting_1285673(100473621, -), ADediting_1285674(100473835, -), ADediting_1285675(100473836, -), ADediting_1285676(100473859, -), ADediting_1285677(100473863, -), ADediting_1585045(100465371, -), ADediting_1585046(100469034, -), ADediting_1585047(100469063, -), ADediting_1585048(100470400, -), ADediting_1585049(100470468, -), ADediting_1585050(100470521, -), ADediting_1585051(100470529, -), ADediting_1585052(100470540, -), ADediting_1585053(100470570, -), ADediting_1585054(100473499, -), ADediting_1585055(100473580, -), ADediting_1585056(100473606, -), ADediting_1585057(100473635, -), ADediting_1663213(100474900, -),

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RNA editing positional annotations for TSC22D4 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1285594chr7_100468493_-intronic
ADediting_1285595chr7_100468692_-intronic
ADediting_1285596chr7_100468734_-intronic
ADediting_1285597chr7_100468966_-intronic
ADediting_1285598chr7_100469000_-intronic
ADediting_1285599chr7_100469009_-intronic
ADediting_1285600chr7_100469014_-intronic
ADediting_1285601chr7_100469021_-intronic
ADediting_1285602chr7_100469022_-intronic
ADediting_1285603chr7_100469023_-intronic
ADediting_1285604chr7_100469043_-intronic
ADediting_1285605chr7_100469105_-intronic
ADediting_1285606chr7_100469111_-intronic
ADediting_1285607chr7_100469115_-intronic
ADediting_1285608chr7_100469144_-intronic
ADediting_1285609chr7_100469151_-intronic
ADediting_1285610chr7_100469296_-intronic
ADediting_1285611chr7_100469297_-intronic
ADediting_1285612chr7_100470358_-intronic
ADediting_1285613chr7_100470359_-intronic
ADediting_1285614chr7_100470368_-intronic
ADediting_1285615chr7_100470384_-intronic
ADediting_1285616chr7_100470394_-intronic
ADediting_1285617chr7_100470397_-intronic
ADediting_1285618chr7_100470407_-intronic
ADediting_1285619chr7_100470420_-intronic
ADediting_1285620chr7_100470424_-intronic
ADediting_1285621chr7_100470429_-intronic
ADediting_1285622chr7_100470430_-intronic
ADediting_1285623chr7_100470456_-intronic
ADediting_1285624chr7_100470465_-intronic
ADediting_1285625chr7_100470467_-intronic
ADediting_1285626chr7_100470493_-intronic
ADediting_1285627chr7_100470518_-intronic
ADediting_1285628chr7_100470523_-intronic
ADediting_1285629chr7_100470524_-intronic
ADediting_1285630chr7_100470532_-intronic
ADediting_1285631chr7_100470537_-intronic
ADediting_1285632chr7_100470578_-intronic
ADediting_1285633chr7_100470579_-intronic
ADediting_1285634chr7_100470585_-intronic
ADediting_1285635chr7_100470595_-intronic
ADediting_1285636chr7_100470706_-intronic
ADediting_1285637chr7_100471477_-intronic
ADediting_1285638chr7_100471480_-intronic
ADediting_1285639chr7_100471483_-intronic
ADediting_1285640chr7_100471495_-intronic
ADediting_1285641chr7_100471497_-intronic
ADediting_1285642chr7_100471510_-intronic
ADediting_1285643chr7_100471514_-intronic
ADediting_1285644chr7_100471535_-intronic
ADediting_1285645chr7_100471536_-intronic
ADediting_1285646chr7_100471537_-intronic
ADediting_1285647chr7_100471542_-intronic
ADediting_1285648chr7_100471548_-intronic
ADediting_1285649chr7_100471557_-intronic
ADediting_1285650chr7_100471560_-intronic
ADediting_1285651chr7_100471605_-intronic
ADediting_1285652chr7_100471616_-intronic
ADediting_1285653chr7_100471618_-intronic
ADediting_1285654chr7_100471628_-intronic
ADediting_1285655chr7_100471640_-intronic
ADediting_1285656chr7_100471657_-intronic
ADediting_1285657chr7_100471658_-intronic
ADediting_1285658chr7_100471664_-intronic
ADediting_1285659chr7_100471696_-intronic
ADediting_1285660chr7_100471702_-intronic
ADediting_1285661chr7_100471706_-intronic
ADediting_1285662chr7_100471713_-intronic
ADediting_1285663chr7_100471738_-intronic
ADediting_1285664chr7_100473502_-intronic
ADediting_1285665chr7_100473527_-intronic
ADediting_1285666chr7_100473534_-intronic
ADediting_1285667chr7_100473574_-intronic
ADediting_1285668chr7_100473579_-intronic
ADediting_1285669chr7_100473602_-intronic
ADediting_1285670chr7_100473618_-intronic
ADediting_1285671chr7_100473619_-intronic
ADediting_1285672chr7_100473620_-intronic
ADediting_1285673chr7_100473621_-intronic
ADediting_1285674chr7_100473835_-intronic
ADediting_1285675chr7_100473836_-intronic
ADediting_1285676chr7_100473859_-intronic
ADediting_1285677chr7_100473863_-intronic
ADediting_1585045chr7_100465371_-intergenic
ADediting_1585046chr7_100469034_-intronic
ADediting_1585047chr7_100469063_-intronic
ADediting_1585048chr7_100470400_-intronic
ADediting_1585049chr7_100470468_-intronic
ADediting_1585050chr7_100470521_-intronic
ADediting_1585051chr7_100470529_-intronic
ADediting_1585052chr7_100470540_-intronic
ADediting_1585053chr7_100470570_-intronic
ADediting_1585054chr7_100473499_-intronic
ADediting_1585055chr7_100473580_-intronic
ADediting_1585056chr7_100473606_-intronic
ADediting_1585057chr7_100473635_-intronic
ADediting_1663213chr7_100474900_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1285595chr7_100468692_-SINEAluName=AluSx1
ADediting_1285596chr7_100468734_-SINEAluName=AluSx1
ADediting_1285597chr7_100468966_-SINEAluName=AluSq
ADediting_1285598chr7_100469000_-SINEAluName=AluSq
ADediting_1285599chr7_100469009_-SINEAluName=AluSq
ADediting_1285600chr7_100469014_-SINEAluName=AluSq
ADediting_1285601chr7_100469021_-SINEAluName=AluSq
ADediting_1285602chr7_100469022_-SINEAluName=AluSq
ADediting_1285603chr7_100469023_-SINEAluName=AluSq
ADediting_1285604chr7_100469043_-SINEAluName=AluSq
ADediting_1285605chr7_100469105_-SINEAluName=AluSq
ADediting_1285606chr7_100469111_-SINEAluName=AluSq
ADediting_1285607chr7_100469115_-SINEAluName=AluSq
ADediting_1285608chr7_100469144_-SINEAluName=AluSq
ADediting_1285609chr7_100469151_-SINEAluName=AluSq
ADediting_1285612chr7_100470358_-SINEAluName=AluSq2
ADediting_1285613chr7_100470359_-SINEAluName=AluSq2
ADediting_1285614chr7_100470368_-SINEAluName=AluSq2
ADediting_1285615chr7_100470384_-SINEAluName=AluSq2
ADediting_1285616chr7_100470394_-SINEAluName=AluSq2
ADediting_1285617chr7_100470397_-SINEAluName=AluSq2
ADediting_1285618chr7_100470407_-SINEAluName=AluSq2
ADediting_1285619chr7_100470420_-SINEAluName=AluSq2
ADediting_1285620chr7_100470424_-SINEAluName=AluSq2
ADediting_1285621chr7_100470429_-SINEAluName=AluSq2
ADediting_1285622chr7_100470430_-SINEAluName=AluSq2
ADediting_1285623chr7_100470456_-SINEAluName=AluSq2
ADediting_1285624chr7_100470465_-SINEAluName=AluSq2
ADediting_1285625chr7_100470467_-SINEAluName=AluSq2
ADediting_1285626chr7_100470493_-SINEAluName=AluSq2
ADediting_1285627chr7_100470518_-SINEAluName=AluSq2
ADediting_1285628chr7_100470523_-SINEAluName=AluSq2
ADediting_1285629chr7_100470524_-SINEAluName=AluSq2
ADediting_1285630chr7_100470532_-SINEAluName=AluSq2
ADediting_1285631chr7_100470537_-SINEAluName=AluSq2
ADediting_1285632chr7_100470578_-SINEAluName=AluSq2
ADediting_1285633chr7_100470579_-SINEAluName=AluSq2
ADediting_1285634chr7_100470585_-SINEAluName=AluSq2
ADediting_1285635chr7_100470595_-SINEAluName=AluSq2
ADediting_1285637chr7_100471477_-SINEAluName=AluSx
ADediting_1285638chr7_100471480_-SINEAluName=AluSx
ADediting_1285639chr7_100471483_-SINEAluName=AluSx
ADediting_1285640chr7_100471495_-SINEAluName=AluSx
ADediting_1285641chr7_100471497_-SINEAluName=AluSx
ADediting_1285642chr7_100471510_-SINEAluName=AluSx
ADediting_1285643chr7_100471514_-SINEAluName=AluSx
ADediting_1285644chr7_100471535_-SINEAluName=AluSx
ADediting_1285645chr7_100471536_-SINEAluName=AluSx
ADediting_1285646chr7_100471537_-SINEAluName=AluSx
ADediting_1285647chr7_100471542_-SINEAluName=AluSx
ADediting_1285648chr7_100471548_-SINEAluName=AluSx
ADediting_1285649chr7_100471557_-SINEAluName=AluSx
ADediting_1285650chr7_100471560_-SINEAluName=AluSx
ADediting_1285651chr7_100471605_-SINEAluName=AluSx
ADediting_1285652chr7_100471616_-SINEAluName=AluSx
ADediting_1285653chr7_100471618_-SINEAluName=AluSx
ADediting_1285654chr7_100471628_-SINEAluName=AluSx
ADediting_1285655chr7_100471640_-SINEAluName=AluSx
ADediting_1285656chr7_100471657_-SINEAluName=AluSx
ADediting_1285657chr7_100471658_-SINEAluName=AluSx
ADediting_1285658chr7_100471664_-SINEAluName=AluSx
ADediting_1285659chr7_100471696_-SINEAluName=AluSx
ADediting_1285660chr7_100471702_-SINEAluName=AluSx
ADediting_1285661chr7_100471706_-SINEAluName=AluSx
ADediting_1285662chr7_100471713_-SINEAluName=AluSx
ADediting_1285663chr7_100471738_-SINEAluName=AluSx
ADediting_1285664chr7_100473502_-SINEAluName=AluSx
ADediting_1285665chr7_100473527_-SINEAluName=AluSx
ADediting_1285666chr7_100473534_-SINEAluName=AluSx
ADediting_1285667chr7_100473574_-SINEAluName=AluSx
ADediting_1285668chr7_100473579_-SINEAluName=AluSx
ADediting_1285669chr7_100473602_-SINEAluName=AluSx
ADediting_1285670chr7_100473618_-SINEAluName=AluSx
ADediting_1285671chr7_100473619_-SINEAluName=AluSx
ADediting_1285672chr7_100473620_-SINEAluName=AluSx
ADediting_1285673chr7_100473621_-SINEAluName=AluSx
ADediting_1285674chr7_100473835_-SINEAluName=FLAM_C
ADediting_1285675chr7_100473836_-SINEAluName=FLAM_C
ADediting_1285676chr7_100473859_-SINEAluName=FLAM_C
ADediting_1285677chr7_100473863_-SINEAluName=FLAM_C
ADediting_1585045chr7_100465371_-SINEAluName=AluSz
ADediting_1585046chr7_100469034_-SINEAluName=AluSq
ADediting_1585047chr7_100469063_-SINEAluName=AluSq
ADediting_1585048chr7_100470400_-SINEAluName=AluSq2
ADediting_1585049chr7_100470468_-SINEAluName=AluSq2
ADediting_1585050chr7_100470521_-SINEAluName=AluSq2
ADediting_1585051chr7_100470529_-SINEAluName=AluSq2
ADediting_1585052chr7_100470540_-SINEAluName=AluSq2
ADediting_1585053chr7_100470570_-SINEAluName=AluSq2
ADediting_1585054chr7_100473499_-SINEAluName=AluSx
ADediting_1585055chr7_100473580_-SINEAluName=AluSx
ADediting_1585056chr7_100473606_-SINEAluName=AluSx
ADediting_1585057chr7_100473635_-SINEAluName=AluSx
ADediting_1663213chr7_100474900_-SINEAluName=AluJo

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RNA A-to-I editing events in the alternative splicing sites for TSC22D4

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_1285663chr7_100471738_-100471734:1004717563ss2iTTTGTTTTTTTCTTTTTTAGATG12.58TTTGTTTTTTTCTTTTTTGGATG4.62
ESADediting_1285652chr7_100471616_-100471609:1004716175ss2eCAGGTGCAT4.89CGGGTGCAT0.56

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TSC22D4

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for TSC22D4

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TSC22D4


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TSC22D4

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for TSC22D4

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1285596chr7_100468734_-0.03879088714737740.1689193925549260.0001450347415715080.3053340159470050.003417714960704970.237579392981506
CERADediting_1285603chr7_100469023_-0.04761322554379940.1620171534000075.21671786659006e-050.3240807557097140.1027347713862250.133750383246831
TCXADediting_1285611chr7_100469297_-0.5798305834772530.04556153833649040.00326568915362592-0.238692165073423.08178270937881e-080.433181545248882
TCXADediting_1285614chr7_100470368_-0.987865244131290.001252305526652090.000930664347320666-0.2676077819362225.01901087299243e-090.454793013377087
DLPFCADediting_1285616chr7_100470394_-0.001796838438899250.1766298023086930.04024067654131460.1165777217976391.64387834858402e-110.370311591507548
TCXADediting_1285616chr7_100470394_-0.669056514018386-0.03518411656569640.0107418211050947-0.2077475440726025.96928399830949e-090.452792037035681
DLPFCADediting_1285617chr7_100470397_-0.01948143927832150.1326356410485970.3764726501095850.05040303338975863.52315308919287e-090.327423078527527
TCXADediting_1285617chr7_100470397_-0.277785959749982-0.08918425234175130.000310895472852919-0.2904876172623993.6764758970763e-090.458353157955893
DLPFCADediting_1285624chr7_100470465_-0.07410187336675990.1015848872035550.991688167607754-0.0005940755591054933.51101615768796e-140.412726642975237
CERADediting_1285627chr7_100470518_-8.11298521004554e-050.3161365937643971.29610611018905e-090.469988800422110.05573404315899540.156549812437174
TCXADediting_1285628chr7_100470523_-0.3413874715881420.0782189589440990.017335120746947-0.1940598176108739.75895951660135e-090.447048323780852
TCXADediting_1285629chr7_100470524_-0.4015323163631780.06899037204092830.0139726439353006-0.2003291587036691.32595618426354e-080.443412022379572
TCXADediting_1285630chr7_100470532_-0.6204112413311140.04076261380852930.12295352949864-0.1264958588754666.24684718816639e-050.320865613707818
CERADediting_1285632chr7_100470578_-0.0003040055062266090.2909356108703477.73324890769863e-050.3170097837257510.6708243825555850.0349845163989085
DLPFCADediting_1285634chr7_100470585_-0.00245067638148760.1714730245646510.03263794800141660.1213868735328643.48444353178937e-100.346710643508778
TCXADediting_1285634chr7_100470585_-0.6247690479898360.04025562429958880.114267844966885-0.1294888280461257.3979795418492e-060.356811786467741
CERADediting_1285637chr7_100471477_-0.007243437075007980.2184381747250090.0001629792572650710.3031136947630080.2807070134440050.0886461767203295
CERADediting_1285638chr7_100471480_-0.01494405993637040.1983936476484072.72165176511816e-050.335397759096170.1296358792162080.12430268437731
CERADediting_1285639chr7_100471483_-0.01005033223326480.2095874213674581.74839667348489e-060.3788474926186670.0003690402775543440.287035767930833
DLPFCADediting_1285643chr7_100471514_-0.08722476310945660.09729657427136410.402360468411805-0.04772755869661054.36690324262368e-150.425836532833365
DLPFCADediting_1285644chr7_100471535_-0.02645356016678770.1260643879855810.6337392409863820.02716645476123531.16385761112561e-080.316909198343266
CERADediting_1285645chr7_100471536_-0.1886236130079560.1079307225041591.76286035966235e-050.3427128274662670.209266360439740.10310718037074
DLPFCADediting_1285646chr7_100471537_-0.0598987736506120.106989466143930.9883203310294730.0008348011923485272.20716385939223e-110.368116944901395
DLPFCADediting_1285653chr7_100471618_-0.1696367791539930.07819869069151180.12167672972216-0.08809254496900575.10589221870625e-200.488748653715918
CERADediting_1285655chr7_100471640_-0.02917658018622980.1781486709152142.58025472099482e-050.3363063473288640.2255045953686450.0995477918216868
TCXADediting_1285656chr7_100471657_-0.708878573218082-0.0307348375617210.0153231805212462-0.1976679448061042.4617860113249e-070.406427663037847
CERADediting_1285661chr7_100471706_-0.008958325718088750.2127340022514891.98412942602483e-060.3769788892063320.2757785845613020.0895562369228351
DLPFCADediting_1285664chr7_100473502_-0.4996255607554720.03848316918606370.284895758564922-0.06092673332923669.75482777714441e-130.390552450549031
DLPFCADediting_1285673chr7_100473621_-0.2300175990013460.06836962633012110.136202229670657-0.08482114013808571.48745773815727e-090.334768123927232
CERADediting_1285677chr7_100473863_-0.009427262670790090.2113434534179190.0001608450485082420.3033654814123380.01113529186559420.206746674651119

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC0.000172955200352280.2117334354480140.2506177659120550.06544471295805157.58474290338796e-510.720261423726761
AC2.37970172625482e-290.6325860633983872.57960399207817e-140.4571681793409681.48277902565092e-350.682005987355945
PCC0.002341951789439390.2189465737996630.05282100782462480.1403386818929567.15105246661562e-070.349602894052116
CER0.00151742307829153-0.2567315272300873.88242076002236e-07-0.4002374559958070.01921366030082420.191005503399372
TCX0.291307413829380.08672447954628034.22054519593577e-08-0.4292788776439492.96983135608357e-250.7200223483028
FP0.119288952001520.1171823763449960.00173633259124242-0.2331503751899563.59105388769308e-120.490643715697206
IFG0.3563621827784380.1925885645393560.56344297317544-0.1213304422401130.004303296164752080.551070353358792
PG0.0036233468404048-0.2123081509590311.39858398351027e-11-0.4693851726903889.14126055037973e-150.528361835611591
STG0.01896577918590280.2555545220053880.100435563372875-0.180467393252075.65203914876888e-100.613140043688159

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Relation with AD stages for TSC22D4

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1285639chr7_100471483_-0.0006823205107604440.321840365096947
CERADediting_1285656chr7_100471657_-0.0004731296621039630.330690124082921
CERADediting_1285657chr7_100471658_-0.001446720142893840.302787685318979
CERADediting_1285661chr7_100471706_-0.0006784193879781310.321981032001702
TCXADediting_1285656chr7_100471657_-0.0001572562880079140.359020207515165

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
TCX3.10634209578036e-050.392858388864688

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RelatedDrugs for TSC22D4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TSC22D4

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource