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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ARHGAP39

check button Gene summary
Gene informationGene symbol

ARHGAP39

Gene ID

80728

Gene nameRho GTPase activating protein 39
SynonymsCrGAP|Vilse
Cytomap

8q24.3

Type of geneprotein-coding
Descriptionrho GTPase-activating protein 39RhoGAP93B homologcrossGAP homolog
Modification date20200313
UniProtAcc

Q9C0H5,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ARHGAP39

GO:0099173

postsynapse organization

24656827


Top

RNA A-to-I events for ARHGAP39

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1393472(144534737, -), ADediting_1393473(144536301, -), ADediting_1393474(144538669, -), ADediting_1393475(144538695, -), ADediting_1393476(144538699, -), ADediting_1393477(144538702, -), ADediting_1393478(144538708, -), ADediting_1393479(144538709, -), ADediting_1393480(144538731, -), ADediting_1393481(144538735, -), ADediting_1393482(144538740, -), ADediting_1393483(144538747, -), ADediting_1393484(144538764, -), ADediting_1393485(144538765, -), ADediting_1393486(144538772, -), ADediting_1393487(144538789, -), ADediting_1393488(144538797, -), ADediting_1393489(144538844, -), ADediting_1393490(144538850, -), ADediting_1393491(144540163, -), ADediting_1393492(144540180, -), ADediting_1393493(144540274, -), ADediting_1393494(144540275, -), ADediting_1393495(144540280, -), ADediting_1393496(144540284, -), ADediting_1393497(144540536, -), ADediting_1393498(144540590, -), ADediting_1393499(144540609, -), ADediting_1393500(144540629, -), ADediting_1393501(144540635, -), ADediting_1393502(144540678, -), ADediting_1393503(144540688, -), ADediting_1393504(144540705, -), ADediting_1393505(144540724, -), ADediting_1393506(144540731, -), ADediting_1393507(144540743, -), ADediting_1393508(144540750, -), ADediting_1393509(144540762, -), ADediting_1393510(144540944, -), ADediting_1393511(144540948, -), ADediting_1393512(144540963, -), ADediting_1393513(144540976, -), ADediting_1393514(144540984, -), ADediting_1393515(144540989, -), ADediting_1393516(144540990, -), ADediting_1393517(144541078, -), ADediting_1393518(144541079, -), ADediting_1393519(144541084, -), ADediting_1393520(144541118, -), ADediting_1393521(144541123, -), ADediting_1393522(144542682, -), ADediting_1393523(144542695, -), ADediting_1393524(144542722, -), ADediting_1393525(144542773, -), ADediting_1393526(144542776, -), ADediting_1393527(144542791, -), ADediting_1393528(144542795, -), ADediting_1393529(144542799, -), ADediting_1393530(144542815, -), ADediting_1393531(144542827, -), ADediting_1393532(144542856, -), ADediting_1393533(144542992, -), ADediting_1393534(144543054, -), ADediting_1393535(144543067, -), ADediting_1393536(144543081, -), ADediting_1393537(144543085, -), ADediting_1393538(144543098, -), ADediting_1393539(144543102, -), ADediting_1393540(144543129, -), ADediting_1393541(144543130, -), ADediting_1393542(144543134, -), ADediting_1393543(144543221, -), ADediting_1393544(144543252, -), ADediting_1393545(144543262, -), ADediting_1393546(144543264, -), ADediting_1393547(144543268, -), ADediting_1393548(144549578, -), ADediting_1393549(144550016, -), ADediting_1393550(144558520, -), ADediting_1393551(144558543, -), ADediting_1393552(144558544, -), ADediting_1393553(144578259, -), ADediting_1393554(144578405, -), ADediting_1393555(144578411, -), ADediting_1393556(144578474, -), ADediting_1393557(144578492, -), ADediting_1393558(144578756, -), ADediting_1393559(144604461, -), ADediting_1393560(144604469, -), ADediting_1393561(144604470, -), ADediting_1393562(144604475, -), ADediting_1393563(144604506, -), ADediting_1393564(144604518, -), ADediting_1393565(144604526, -), ADediting_1393566(144604538, -), ADediting_1393567(144604545, -), ADediting_1393568(144604546, -), ADediting_1393569(144604548, -), ADediting_1393570(144604556, -), ADediting_1393571(144604557, -), ADediting_1393572(144604560, -), ADediting_1393573(144605118, -), ADediting_1393574(144605150, -), ADediting_1393575(144605185, -), ADediting_1393576(144605247, -), ADediting_1589982(144538690, -), ADediting_1589983(144538703, -), ADediting_1589984(144540224, -), ADediting_1589985(144540296, -), ADediting_1589986(144540784, -), ADediting_1589987(144550152, -), ADediting_1589988(144550162, -), ADediting_1589989(144550206, -), ADediting_1589990(144550269, -), ADediting_1589991(144550273, -), ADediting_1589992(144605094, -), ADediting_1589993(144605124, -), ADediting_1589994(144605130, -), ADediting_1589995(144605166, -), ADediting_1589996(144605209, -), ADediting_1668769(144578361, -),

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RNA editing positional annotations for ARHGAP39 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1393472chr8_144534737_-intronic
ADediting_1393473chr8_144536301_-intronic
ADediting_1393474chr8_144538669_-intronic
ADediting_1393475chr8_144538695_-intronic
ADediting_1393476chr8_144538699_-intronic
ADediting_1393477chr8_144538702_-intronic
ADediting_1393478chr8_144538708_-intronic
ADediting_1393479chr8_144538709_-intronic
ADediting_1393480chr8_144538731_-intronic
ADediting_1393481chr8_144538735_-intronic
ADediting_1393482chr8_144538740_-intronic
ADediting_1393483chr8_144538747_-intronic
ADediting_1393484chr8_144538764_-intronic
ADediting_1393485chr8_144538765_-intronic
ADediting_1393486chr8_144538772_-intronic
ADediting_1393487chr8_144538789_-intronic
ADediting_1393488chr8_144538797_-intronic
ADediting_1393489chr8_144538844_-intronic
ADediting_1393490chr8_144538850_-intronic
ADediting_1393491chr8_144540163_-intronic
ADediting_1393492chr8_144540180_-intronic
ADediting_1393493chr8_144540274_-intronic
ADediting_1393494chr8_144540275_-intronic
ADediting_1393495chr8_144540280_-intronic
ADediting_1393496chr8_144540284_-intronic
ADediting_1393497chr8_144540536_-intronic
ADediting_1393498chr8_144540590_-intronic
ADediting_1393499chr8_144540609_-intronic
ADediting_1393500chr8_144540629_-intronic
ADediting_1393501chr8_144540635_-intronic
ADediting_1393502chr8_144540678_-intronic
ADediting_1393503chr8_144540688_-intronic
ADediting_1393504chr8_144540705_-intronic
ADediting_1393505chr8_144540724_-intronic
ADediting_1393506chr8_144540731_-intronic
ADediting_1393507chr8_144540743_-intronic
ADediting_1393508chr8_144540750_-intronic
ADediting_1393509chr8_144540762_-intronic
ADediting_1393510chr8_144540944_-intronic
ADediting_1393511chr8_144540948_-intronic
ADediting_1393512chr8_144540963_-intronic
ADediting_1393513chr8_144540976_-intronic
ADediting_1393514chr8_144540984_-intronic
ADediting_1393515chr8_144540989_-intronic
ADediting_1393516chr8_144540990_-intronic
ADediting_1393517chr8_144541078_-intronic
ADediting_1393518chr8_144541079_-intronic
ADediting_1393519chr8_144541084_-intronic
ADediting_1393520chr8_144541118_-intronic
ADediting_1393521chr8_144541123_-intronic
ADediting_1393522chr8_144542682_-intronic
ADediting_1393523chr8_144542695_-intronic
ADediting_1393524chr8_144542722_-intronic
ADediting_1393525chr8_144542773_-intronic
ADediting_1393526chr8_144542776_-intronic
ADediting_1393527chr8_144542791_-intronic
ADediting_1393528chr8_144542795_-intronic
ADediting_1393529chr8_144542799_-intronic
ADediting_1393530chr8_144542815_-intronic
ADediting_1393531chr8_144542827_-intronic
ADediting_1393532chr8_144542856_-intronic
ADediting_1393533chr8_144542992_-intronic
ADediting_1393534chr8_144543054_-intronic
ADediting_1393535chr8_144543067_-intronic
ADediting_1393536chr8_144543081_-intronic
ADediting_1393537chr8_144543085_-intronic
ADediting_1393538chr8_144543098_-intronic
ADediting_1393539chr8_144543102_-intronic
ADediting_1393540chr8_144543129_-intronic
ADediting_1393541chr8_144543130_-intronic
ADediting_1393542chr8_144543134_-intronic
ADediting_1393543chr8_144543221_-intronic
ADediting_1393544chr8_144543252_-intronic
ADediting_1393545chr8_144543262_-intronic
ADediting_1393546chr8_144543264_-intronic
ADediting_1393547chr8_144543268_-intronic
ADediting_1393548chr8_144549578_-intronic
ADediting_1393549chr8_144550016_-intronic
ADediting_1393550chr8_144558520_-intronic
ADediting_1393551chr8_144558543_-intronic
ADediting_1393552chr8_144558544_-intronic
ADediting_1393553chr8_144578259_-intronic
ADediting_1393554chr8_144578405_-intronic
ADediting_1393555chr8_144578411_-intronic
ADediting_1393556chr8_144578474_-intronic
ADediting_1393557chr8_144578492_-intronic
ADediting_1393558chr8_144578756_-intronic
ADediting_1393559chr8_144604461_-intronic
ADediting_1393560chr8_144604469_-intronic
ADediting_1393561chr8_144604470_-intronic
ADediting_1393562chr8_144604475_-intronic
ADediting_1393563chr8_144604506_-intronic
ADediting_1393564chr8_144604518_-intronic
ADediting_1393565chr8_144604526_-intronic
ADediting_1393566chr8_144604538_-intronic
ADediting_1393567chr8_144604545_-intronic
ADediting_1393568chr8_144604546_-intronic
ADediting_1393569chr8_144604548_-intronic
ADediting_1393570chr8_144604556_-intronic
ADediting_1393571chr8_144604557_-intronic
ADediting_1393572chr8_144604560_-intronic
ADediting_1393573chr8_144605118_-intronic
ADediting_1393574chr8_144605150_-intronic
ADediting_1393575chr8_144605185_-intronic
ADediting_1393576chr8_144605247_-intronic
ADediting_1589982chr8_144538690_-intronic
ADediting_1589983chr8_144538703_-intronic
ADediting_1589984chr8_144540224_-intronic
ADediting_1589985chr8_144540296_-intronic
ADediting_1589986chr8_144540784_-intronic
ADediting_1589987chr8_144550152_-intronic
ADediting_1589988chr8_144550162_-intronic
ADediting_1589989chr8_144550206_-intronic
ADediting_1589990chr8_144550269_-intronic
ADediting_1589991chr8_144550273_-intronic
ADediting_1589992chr8_144605094_-intronic
ADediting_1589993chr8_144605124_-intronic
ADediting_1589994chr8_144605130_-intronic
ADediting_1589995chr8_144605166_-intronic
ADediting_1589996chr8_144605209_-intronic
ADediting_1668769chr8_144578361_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1393474chr8_144538669_-SINEAluName=AluSz
ADediting_1393475chr8_144538695_-SINEAluName=AluSz
ADediting_1393476chr8_144538699_-SINEAluName=AluSz
ADediting_1393477chr8_144538702_-SINEAluName=AluSz
ADediting_1393478chr8_144538708_-SINEAluName=AluSz
ADediting_1393479chr8_144538709_-SINEAluName=AluSz
ADediting_1393480chr8_144538731_-SINEAluName=AluSz
ADediting_1393481chr8_144538735_-SINEAluName=AluSz
ADediting_1393482chr8_144538740_-SINEAluName=AluSz
ADediting_1393483chr8_144538747_-SINEAluName=AluSz
ADediting_1393484chr8_144538764_-SINEAluName=AluSz
ADediting_1393485chr8_144538765_-SINEAluName=AluSz
ADediting_1393486chr8_144538772_-SINEAluName=AluSz
ADediting_1393487chr8_144538789_-SINEAluName=AluSz
ADediting_1393488chr8_144538797_-SINEAluName=AluSz
ADediting_1393489chr8_144538844_-SINEAluName=AluSz
ADediting_1393490chr8_144538850_-SINEAluName=AluSz
ADediting_1393491chr8_144540163_-SINEAluName=AluJr4
ADediting_1393492chr8_144540180_-SINEAluName=AluJr4
ADediting_1393493chr8_144540274_-SINEAluName=AluJr4
ADediting_1393494chr8_144540275_-SINEAluName=AluJr4
ADediting_1393495chr8_144540280_-SINEAluName=AluJr4
ADediting_1393496chr8_144540284_-SINEAluName=AluJr4
ADediting_1393497chr8_144540536_-SINEAluName=AluJb
ADediting_1393498chr8_144540590_-SINEAluName=AluJb
ADediting_1393499chr8_144540609_-SINEAluName=AluJb
ADediting_1393500chr8_144540629_-SINEAluName=AluJb
ADediting_1393501chr8_144540635_-SINEAluName=AluJb
ADediting_1393502chr8_144540678_-SINEAluName=AluJb
ADediting_1393503chr8_144540688_-SINEAluName=AluJb
ADediting_1393504chr8_144540705_-SINEAluName=AluJb
ADediting_1393505chr8_144540724_-SINEAluName=AluJb
ADediting_1393506chr8_144540731_-SINEAluName=AluJb
ADediting_1393507chr8_144540743_-SINEAluName=AluJb
ADediting_1393508chr8_144540750_-SINEAluName=AluJb
ADediting_1393509chr8_144540762_-SINEAluName=AluJb
ADediting_1393510chr8_144540944_-SINEAluName=AluSx1
ADediting_1393511chr8_144540948_-SINEAluName=AluSx1
ADediting_1393512chr8_144540963_-SINEAluName=AluSx1
ADediting_1393513chr8_144540976_-SINEAluName=AluSx1
ADediting_1393514chr8_144540984_-SINEAluName=AluSx1
ADediting_1393515chr8_144540989_-SINEAluName=AluSx1
ADediting_1393516chr8_144540990_-SINEAluName=AluSx1
ADediting_1393517chr8_144541078_-SINEAluName=AluSx1
ADediting_1393518chr8_144541079_-SINEAluName=AluSx1
ADediting_1393519chr8_144541084_-SINEAluName=AluSx1
ADediting_1393520chr8_144541118_-SINEAluName=AluSx1
ADediting_1393521chr8_144541123_-SINEAluName=AluSx1
ADediting_1393522chr8_144542682_-SINEAluName=AluSx
ADediting_1393523chr8_144542695_-SINEAluName=AluSx
ADediting_1393524chr8_144542722_-SINEAluName=AluSx
ADediting_1393525chr8_144542773_-SINEAluName=AluSx
ADediting_1393526chr8_144542776_-SINEAluName=AluSx
ADediting_1393527chr8_144542791_-SINEAluName=AluSx
ADediting_1393528chr8_144542795_-SINEAluName=AluSx
ADediting_1393529chr8_144542799_-SINEAluName=AluSx
ADediting_1393530chr8_144542815_-SINEAluName=AluSx
ADediting_1393531chr8_144542827_-SINEAluName=AluSx
ADediting_1393532chr8_144542856_-SINEAluName=AluSx
ADediting_1393533chr8_144542992_-SINEAluName=AluJo
ADediting_1393534chr8_144543054_-SINEAluName=AluJo
ADediting_1393535chr8_144543067_-SINEAluName=AluJo
ADediting_1393536chr8_144543081_-SINEAluName=AluJo
ADediting_1393537chr8_144543085_-SINEAluName=AluJo
ADediting_1393538chr8_144543098_-SINEAluName=AluJo
ADediting_1393539chr8_144543102_-SINEAluName=AluJo
ADediting_1393540chr8_144543129_-SINEAluName=AluJo
ADediting_1393541chr8_144543130_-SINEAluName=AluJo
ADediting_1393542chr8_144543134_-SINEAluName=AluJo
ADediting_1393543chr8_144543221_-SINEAluName=AluJo
ADediting_1393544chr8_144543252_-SINEAluName=AluJo
ADediting_1393545chr8_144543262_-SINEAluName=AluJo
ADediting_1393546chr8_144543264_-SINEAluName=AluJo
ADediting_1393547chr8_144543268_-SINEAluName=AluJo
ADediting_1393548chr8_144549578_-SINEAluName=AluSg
ADediting_1393549chr8_144550016_-SINEAluName=AluJr
ADediting_1393550chr8_144558520_-SINEAluName=AluSx1
ADediting_1393551chr8_144558543_-SINEAluName=AluSx1
ADediting_1393552chr8_144558544_-SINEAluName=AluSx1
ADediting_1393553chr8_144578259_-SINEAluName=AluSz6
ADediting_1393554chr8_144578405_-SINEAluName=AluSz6
ADediting_1393555chr8_144578411_-SINEAluName=AluSz6
ADediting_1393556chr8_144578474_-SINEAluName=AluSz6
ADediting_1393557chr8_144578492_-SINEAluName=AluSz6
ADediting_1393558chr8_144578756_-SINEAluName=AluJb
ADediting_1393559chr8_144604461_-SINEAluName=AluJo
ADediting_1393560chr8_144604469_-SINEAluName=AluJo
ADediting_1393561chr8_144604470_-SINEAluName=AluJo
ADediting_1393562chr8_144604475_-SINEAluName=AluJo
ADediting_1393563chr8_144604506_-SINEAluName=AluJo
ADediting_1393564chr8_144604518_-SINEAluName=AluJo
ADediting_1393565chr8_144604526_-SINEAluName=AluJo
ADediting_1393566chr8_144604538_-SINEAluName=AluJo
ADediting_1393567chr8_144604545_-SINEAluName=AluJo
ADediting_1393568chr8_144604546_-SINEAluName=AluJo
ADediting_1393569chr8_144604548_-SINEAluName=AluJo
ADediting_1393570chr8_144604556_-SINEAluName=AluJo
ADediting_1393571chr8_144604557_-SINEAluName=AluJo
ADediting_1393572chr8_144604560_-SINEAluName=AluJo
ADediting_1393573chr8_144605118_-SINEAluName=AluJo
ADediting_1393574chr8_144605150_-SINEAluName=AluJo
ADediting_1393575chr8_144605185_-SINEAluName=AluJo
ADediting_1393576chr8_144605247_-SINEAluName=AluJo
ADediting_1589982chr8_144538690_-SINEAluName=AluSz
ADediting_1589983chr8_144538703_-SINEAluName=AluSz
ADediting_1589984chr8_144540224_-SINEAluName=AluJr4
ADediting_1589985chr8_144540296_-SINEAluName=AluJr4
ADediting_1589986chr8_144540784_-SINEAluName=AluJb
ADediting_1589987chr8_144550152_-SINEAluName=AluJr
ADediting_1589988chr8_144550162_-SINEAluName=AluJr
ADediting_1589989chr8_144550206_-SINEAluName=AluJr
ADediting_1589990chr8_144550269_-SINEAluName=AluJr
ADediting_1589991chr8_144550273_-SINEAluName=AluJr
ADediting_1589992chr8_144605094_-SINEAluName=AluJo
ADediting_1589993chr8_144605124_-SINEAluName=AluJo
ADediting_1589994chr8_144605130_-SINEAluName=AluJo
ADediting_1589995chr8_144605166_-SINEAluName=AluJo
ADediting_1589996chr8_144605209_-SINEAluName=AluJo
ADediting_1668769chr8_144578361_-SINEAluName=AluSz6

Top

RNA A-to-I editing events in the alternative splicing sites for ARHGAP39

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for ARHGAP39

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ARHGAP39

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ARHGAP39


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1631458chr19_40282624_-ENSG00000147799.11ENST00000276826.5ARHGAP39-201hsa-miR-641chr81445303911445303977mer-m8144530390144530413140-15.53
ADediting_1631458chr19_40282624_-ENSG00000147799.11ENST00000377307.6ARHGAP39-202hsa-miR-641chr81445303911445303977mer-m8144530390144530413140-15.53
ADediting_496066chr15_66496985_-ENSG00000147799.11ENST00000276826.5ARHGAP39-201hsa-miR-4512chr81445302921445302987mer-m8144530291144530312140-13.6
ADediting_496066chr15_66496985_-ENSG00000147799.11ENST00000377307.6ARHGAP39-202hsa-miR-4512chr81445302921445302987mer-m8144530291144530312140-13.6

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_107020chr1_37500952_-ENSG00000147799.11ENST00000276826.5ARHGAP39-201hsa-miR-5581-3pchr81445292241445292307mer-m8144529223144529244147-11.45
ADediting_107020chr1_37500952_-ENSG00000147799.11ENST00000377307.6ARHGAP39-202hsa-miR-5581-3pchr81445292241445292307mer-m8144529223144529244147-11.45

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ARHGAP39

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ARHGAP39

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1393495chr8_144540280_-5.34318324647426e-050.3236554827314530.003108925179980650.2398896534011710.02416056578116940.184048732446848
TCXADediting_1393495chr8_144540280_-4.83213583481062e-070.3972188890092770.03628584008644460.1711191801360351.10455947777538e-050.350387400118948
TCXADediting_1393496chr8_144540284_-8.94021786516776e-070.3885679345558110.02528156602831930.1826448906086620.0003485485562092690.288190824492114
CERADediting_1393500chr8_144540629_-2.35172858486599e-050.3378789662916740.00176681553781640.2532506892770350.941247565175658-0.00606844732496368
CERADediting_1393504chr8_144540705_-0.0001227085270487250.3084853024864832.9383406000999e-050.3340881204211810.05692036896777860.155807215447198
CERADediting_1393506chr8_144540731_-0.0003623365719207730.2874069569959290.0001174586264815590.30930378715880.3555128055303370.0759665430438294
DLPFCADediting_1393515chr8_144540989_-0.3749218555692420.0505668142003220.68474374428532-0.02314959019934124.89983687206743e-080.303696757201176
TCXADediting_1393526chr8_144542776_-0.2545864056753890.09360045291168950.21783299125075-0.1012058289708250.0001137456287232370.309903539744625
TCXADediting_1393541chr8_144543130_-0.03095832722386640.176260780747790.648152678181107-0.03756024661336748.08839939070916e-050.316191958052964
TCXADediting_1393545chr8_144543262_-0.002653369553782860.2437079812604680.1822538973989550.1094963986399610.0001315165029647570.307182797153166

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.01942317404204e-310.6001590685679062.42707217008157e-440.6854104946398692.43157473910189e-080.310218064566206
AC4.42696700484296e-090.3603507050467037.80604553274935e-080.3317213507892941.29197754105217e-060.30056810182474
PCC1.00648202724483e-090.4237639341710352.08218391915023e-120.4801561332527630.000176451057793580.268152997582225
CER2.8331362251443e-070.4045319331505631.48923192040899e-130.5561303016223570.008428863604422660.21438359342061
TCX1.77316421416791e-170.6227157782783332.53097573670477e-170.6203662422251170.119997066022750.127495654323
FP1.27480584317433e-090.4351898809881150.09931670998127930.1239323756491364.61399771717117e-080.395612537386876
IFG6.06358643769165e-060.7724322336842526.96617806639701e-050.710227231936710.04395137428099270.406146943240874
STG4.53186651507303e-100.6158177900825620.0003508519372363560.3809090980744952.7309998117243e-050.44064433822921

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Relation with AD stages for ARHGAP39

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1393506chr8_144540731_-0.000546388188134930.327242107117961
CERADediting_1393526chr8_144542776_-0.0001914474469414330.351490401960266
TCXADediting_1393498chr8_144540590_-0.001283040581254680.308714173478631

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.0002726427012797520.343533697074466

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RelatedDrugs for ARHGAP39

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARHGAP39

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource