ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for PNPLA3

Gene summary

Gene information	Gene symbol	PNPLA3
	Gene ID	80339
	Gene name	patatin like phospholipase domain containing 3
	Synonyms	ADPN\|C22orf20\|iPLA(2)epsilon
	Cytomap	22q13.31
	Type of gene	protein-coding
	Description	1-acylglycerol-3-phosphate O-acyltransferase PNPLA3acylglycerol O-acyltransferaseacylglycerol transacylaseadiponutrincalcium-independent phospholipase A2-epsiloniPLA2-epsiloniPLA2epsilonlysophosphatidic acid acyltransferasepatatin-like phospholipa
	Modification date	20200313
	UniProtAcc	Q9NST1,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
PNPLA3	GO:0001676	long-chain fatty acid metabolic process	22560221
PNPLA3	GO:0006650	glycerophospholipid metabolic process	22560221
PNPLA3	GO:0006654	phosphatidic acid biosynthetic process	22560221
PNPLA3	GO:0019432	triglyceride biosynthetic process	15364929\|22560221
PNPLA3	GO:0019433	triglyceride catabolic process	15364929\|22560221
PNPLA3	GO:0036153	triglyceride acyl-chain remodeling	24511104

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RNA A-to-I events for PNPLA3

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_1002340(43924855, +), ADediting_1002341(43929858, +), ADediting_1002342(43929859, +), ADediting_1002343(43929871, +), ADediting_1002344(43930942, +), ADediting_1002345(43931072, +), ADediting_1002346(43933499, +), ADediting_1002347(43933609, +), ADediting_1002348(43933621, +), ADediting_1002349(43934084, +), ADediting_1002350(43934088, +), ADediting_1002351(43934097, +), ADediting_1002352(43934102, +), ADediting_1002353(43934196, +), ADediting_1002354(43934223, +), ADediting_1002355(43934296, +), ADediting_1002356(43939178, +), ADediting_1002357(43939741, +), ADediting_1002358(43940885, +), ADediting_1002359(43940929, +), ADediting_1002360(43943845, +), ADediting_1002361(43943858, +), ADediting_1002362(43943906, +), ADediting_1002363(43943946, +), ADediting_1002364(43943954, +), ADediting_1002365(43943972, +), ADediting_1002366(43943997, +), ADediting_1002367(43944047, +), ADediting_1002368(43944048, +), ADediting_1002369(43944060, +), ADediting_1002370(43947103, +), ADediting_1002371(43947104, +), ADediting_1002372(43947125, +), ADediting_1002373(43947134, +), ADediting_1002374(43947144, +), ADediting_1002375(43947149, +), ADediting_1002376(43947157, +), ADediting_1002377(43947158, +), ADediting_1002378(43947173, +), ADediting_1002379(43947177, +), ADediting_1002380(43947182, +), ADediting_1002381(43947183, +), ADediting_1002382(43947203, +), ADediting_1002383(43947208, +), ADediting_1002384(43947220, +), ADediting_1002385(43947238, +), ADediting_1002386(43947239, +), ADediting_1002387(43947244, +), ADediting_1002388(43947265, +), ADediting_1002389(43947274, +), ADediting_1002390(43947280, +), ADediting_1002391(43947284, +), ADediting_1002392(43947287, +), ADediting_1002393(43947316, +), ADediting_1002394(43947425, +), ADediting_1002395(43949228, +), ADediting_1002396(43949335, +), ADediting_1002397(43949380, +), ADediting_1002398(43949387, +), ADediting_1002399(43949390, +), ADediting_1002400(43949393, +), ADediting_1002401(43949398, +), ADediting_1002402(43949400, +), ADediting_1002403(43949401, +), ADediting_1002404(43949414, +), ADediting_1002405(43949416, +), ADediting_1002406(43949417, +), ADediting_1002407(43949436, +), ADediting_1002408(43949437, +), ADediting_1002409(43949438, +), ADediting_1002410(43949490, +), ADediting_1002411(43949496, +), ADediting_1002412(43949506, +), ADediting_1002413(43949512, +), ADediting_1002414(43949516, +), ADediting_1002415(43949517, +), ADediting_1002416(43949526, +), ADediting_1002417(43949532, +), ADediting_1002418(43949535, +), ADediting_1002419(43949561, +), ADediting_1002420(43949567, +), ADediting_1002421(43949586, +), ADediting_1002422(43949588, +), ADediting_1002423(43949595, +), ADediting_1002424(43949613, +), ADediting_1002425(43949614, +), ADediting_1002426(43949635, +), ADediting_1002427(43949642, +), ADediting_1002428(43949816, +), ADediting_1002429(43949817, +), ADediting_1002430(43949822, +), ADediting_1002431(43949838, +), ADediting_1002432(43949847, +), ADediting_1002433(43949857, +), ADediting_1002434(43949862, +), ADediting_1002435(43949875, +), ADediting_1002436(43949876, +), ADediting_1002437(43949886, +), ADediting_1002438(43949895, +), ADediting_1002439(43949896, +), ADediting_1002440(43949910, +), ADediting_1002441(43949911, +), ADediting_1002442(43949912, +), ADediting_1002443(43949916, +), ADediting_1002444(43949919, +), ADediting_1002445(43949920, +), ADediting_1002446(43949921, +), ADediting_1002447(43949925, +), ADediting_1002448(43949929, +), ADediting_1002449(43949997, +), ADediting_1002450(43950013, +), ADediting_1002451(43950153, +), ADediting_1002452(43950159, +), ADediting_1002453(43950173, +), ADediting_1002454(43950178, +), ADediting_1002455(43950187, +), ADediting_1002456(43950207, +), ADediting_1002457(43950208, +), ADediting_1002458(43950211, +), ADediting_1002459(43950225, +), ADediting_1002460(43950233, +), ADediting_1002461(43950234, +), ADediting_1002462(43950636, +), ADediting_1002463(43950665, +), ADediting_1002464(43950670, +), ADediting_1002465(43950681, +), ADediting_1002466(43950684, +), ADediting_1002467(43950686, +), ADediting_1002468(43950696, +), ADediting_1002469(43950703, +), ADediting_1002470(43950716, +), ADediting_1002471(43950717, +), ADediting_1002472(43950721, +), ADediting_1002473(43950729, +), ADediting_1002474(43950742, +), ADediting_1002475(43950743, +), ADediting_1002476(43950746, +), ADediting_1002477(43950752, +), ADediting_1002478(43950753, +), ADediting_1002479(43950756, +), ADediting_1002480(43950758, +), ADediting_1002481(43950774, +), ADediting_1002482(43950778, +), ADediting_1002483(43950782, +), ADediting_1002484(43950795, +), ADediting_1002485(43950801, +), ADediting_1002486(43950821, +), ADediting_1002487(43950833, +), ADediting_1002488(43950834, +), ADediting_1002489(43950846, +), ADediting_1002490(43950847, +), ADediting_1002491(43950851, +), ADediting_1002492(43950873, +), ADediting_1002493(43950874, +), ADediting_1002494(43950880, +), ADediting_1002495(43950886, +), ADediting_1002496(43950902, +), ADediting_1002497(43951043, +), ADediting_1002498(43951061, +), ADediting_1002499(43951062, +), ADediting_1002500(43951067, +), ADediting_1002501(43951088, +), ADediting_1002502(43951094, +), ADediting_1002503(43951097, +), ADediting_1002504(43951101, +), ADediting_1002505(43951102, +), ADediting_1002506(43951106, +), ADediting_1002507(43951137, +), ADediting_1002508(43951143, +), ADediting_1002509(43951146, +), ADediting_1002510(43951147, +), ADediting_1002511(43951148, +), ADediting_1002512(43951149, +), ADediting_1002513(43951151, +), ADediting_1002514(43951156, +), ADediting_1002515(43951158, +), ADediting_1002516(43951159, +), ADediting_1002517(43951162, +), ADediting_1002518(43951170, +), ADediting_1002519(43951188, +), ADediting_1002520(43951189, +), ADediting_1002521(43951194, +), ADediting_1002522(43951201, +), ADediting_1002523(43951211, +), ADediting_1002524(43951215, +), ADediting_1002525(43951218, +), ADediting_1002526(43951220, +), ADediting_1002527(43951224, +), ADediting_1002528(43951229, +), ADediting_1002529(43951230, +), ADediting_1002530(43951234, +), ADediting_1002531(43951237, +), ADediting_1002532(43951250, +), ADediting_1002533(43951276, +), ADediting_1571284(43947109, +), ADediting_1571285(43947163, +), ADediting_1571286(43947180, +), ADediting_1571287(43947181, +), ADediting_1571288(43949492, +), ADediting_1571289(43949685, +), ADediting_1571290(43949808, +), ADediting_1571291(43949852, +), ADediting_1571292(43949885, +), ADediting_1571293(43949907, +), ADediting_1571294(43949922, +), ADediting_1571295(43949951, +), ADediting_1571296(43949952, +), ADediting_1571297(43950017, +), ADediting_1571298(43950156, +), ADediting_1571299(43950872, +), ADediting_1571300(43951150, +), ADediting_1571301(43951221, +), ADediting_1642945(43960528, +),

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RNA editing positional annotations for PNPLA3 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_1002340	chr22_43924855_+	intronic
ADediting_1002341	chr22_43929858_+	intronic
ADediting_1002342	chr22_43929859_+	intronic
ADediting_1002343	chr22_43929871_+	intronic
ADediting_1002344	chr22_43930942_+	intronic
ADediting_1002345	chr22_43931072_+	intronic
ADediting_1002346	chr22_43933499_+	intronic
ADediting_1002347	chr22_43933609_+	intronic
ADediting_1002348	chr22_43933621_+	intronic
ADediting_1002349	chr22_43934084_+	intronic
ADediting_1002350	chr22_43934088_+	intronic
ADediting_1002351	chr22_43934097_+	intronic
ADediting_1002352	chr22_43934102_+	intronic
ADediting_1002353	chr22_43934196_+	intronic
ADediting_1002354	chr22_43934223_+	intronic
ADediting_1002355	chr22_43934296_+	intronic
ADediting_1002356	chr22_43939178_+	intronic
ADediting_1002357	chr22_43939741_+	intronic
ADediting_1002358	chr22_43940885_+	intronic
ADediting_1002359	chr22_43940929_+	intronic
ADediting_1002360	chr22_43943845_+	intronic
ADediting_1002361	chr22_43943858_+	intronic
ADediting_1002362	chr22_43943906_+	intronic
ADediting_1002363	chr22_43943946_+	intronic
ADediting_1002364	chr22_43943954_+	intronic
ADediting_1002365	chr22_43943972_+	intronic
ADediting_1002366	chr22_43943997_+	intronic
ADediting_1002367	chr22_43944047_+	intronic
ADediting_1002368	chr22_43944048_+	intronic
ADediting_1002369	chr22_43944060_+	intronic
ADediting_1002370	chr22_43947103_+	UTR3
ADediting_1002371	chr22_43947104_+	UTR3
ADediting_1002372	chr22_43947125_+	UTR3
ADediting_1002373	chr22_43947134_+	UTR3
ADediting_1002374	chr22_43947144_+	UTR3
ADediting_1002375	chr22_43947149_+	UTR3
ADediting_1002376	chr22_43947157_+	UTR3
ADediting_1002377	chr22_43947158_+	UTR3
ADediting_1002378	chr22_43947173_+	UTR3
ADediting_1002379	chr22_43947177_+	UTR3
ADediting_1002380	chr22_43947182_+	UTR3
ADediting_1002381	chr22_43947183_+	UTR3
ADediting_1002382	chr22_43947203_+	UTR3
ADediting_1002383	chr22_43947208_+	UTR3
ADediting_1002384	chr22_43947220_+	UTR3
ADediting_1002385	chr22_43947238_+	UTR3
ADediting_1002386	chr22_43947239_+	UTR3
ADediting_1002387	chr22_43947244_+	UTR3
ADediting_1002388	chr22_43947265_+	UTR3
ADediting_1002389	chr22_43947274_+	UTR3
ADediting_1002390	chr22_43947280_+	UTR3
ADediting_1002391	chr22_43947284_+	UTR3
ADediting_1002392	chr22_43947287_+	UTR3
ADediting_1002393	chr22_43947316_+	UTR3
ADediting_1002394	chr22_43947425_+	UTR3
ADediting_1002395	chr22_43949228_+	intronic
ADediting_1002396	chr22_43949335_+	intronic
ADediting_1002397	chr22_43949380_+	intronic
ADediting_1002398	chr22_43949387_+	intronic
ADediting_1002399	chr22_43949390_+	intronic
ADediting_1002400	chr22_43949393_+	intronic
ADediting_1002401	chr22_43949398_+	intronic
ADediting_1002402	chr22_43949400_+	intronic
ADediting_1002403	chr22_43949401_+	intronic
ADediting_1002404	chr22_43949414_+	intronic
ADediting_1002405	chr22_43949416_+	intronic
ADediting_1002406	chr22_43949417_+	intronic
ADediting_1002407	chr22_43949436_+	intronic
ADediting_1002408	chr22_43949437_+	intronic
ADediting_1002409	chr22_43949438_+	intronic
ADediting_1002410	chr22_43949490_+	intronic
ADediting_1002411	chr22_43949496_+	intronic
ADediting_1002412	chr22_43949506_+	intronic
ADediting_1002413	chr22_43949512_+	intronic
ADediting_1002414	chr22_43949516_+	intronic
ADediting_1002415	chr22_43949517_+	intronic
ADediting_1002416	chr22_43949526_+	intronic
ADediting_1002417	chr22_43949532_+	intronic
ADediting_1002418	chr22_43949535_+	intronic
ADediting_1002419	chr22_43949561_+	intronic
ADediting_1002420	chr22_43949567_+	intronic
ADediting_1002421	chr22_43949586_+	intronic
ADediting_1002422	chr22_43949588_+	intronic
ADediting_1002423	chr22_43949595_+	intronic
ADediting_1002424	chr22_43949613_+	intronic
ADediting_1002425	chr22_43949614_+	intronic
ADediting_1002426	chr22_43949635_+	intronic
ADediting_1002427	chr22_43949642_+	intronic
ADediting_1002428	chr22_43949816_+	intronic
ADediting_1002429	chr22_43949817_+	intronic
ADediting_1002430	chr22_43949822_+	intronic
ADediting_1002431	chr22_43949838_+	intronic
ADediting_1002432	chr22_43949847_+	intronic
ADediting_1002433	chr22_43949857_+	intronic
ADediting_1002434	chr22_43949862_+	intronic
ADediting_1002435	chr22_43949875_+	intronic
ADediting_1002436	chr22_43949876_+	intronic
ADediting_1002437	chr22_43949886_+	intronic
ADediting_1002438	chr22_43949895_+	intronic
ADediting_1002439	chr22_43949896_+	intronic
ADediting_1002440	chr22_43949910_+	intronic
ADediting_1002441	chr22_43949911_+	intronic
ADediting_1002442	chr22_43949912_+	intronic
ADediting_1002443	chr22_43949916_+	intronic
ADediting_1002444	chr22_43949919_+	intronic
ADediting_1002445	chr22_43949920_+	intronic
ADediting_1002446	chr22_43949921_+	intronic
ADediting_1002447	chr22_43949925_+	intronic
ADediting_1002448	chr22_43949929_+	intronic
ADediting_1002449	chr22_43949997_+	intronic
ADediting_1002450	chr22_43950013_+	intronic
ADediting_1002451	chr22_43950153_+	intronic
ADediting_1002452	chr22_43950159_+	intronic
ADediting_1002453	chr22_43950173_+	intronic
ADediting_1002454	chr22_43950178_+	intronic
ADediting_1002455	chr22_43950187_+	intronic
ADediting_1002456	chr22_43950207_+	intronic
ADediting_1002457	chr22_43950208_+	intronic
ADediting_1002458	chr22_43950211_+	intronic
ADediting_1002459	chr22_43950225_+	intronic
ADediting_1002460	chr22_43950233_+	intronic
ADediting_1002461	chr22_43950234_+	intronic
ADediting_1002462	chr22_43950636_+	intronic
ADediting_1002463	chr22_43950665_+	intronic
ADediting_1002464	chr22_43950670_+	intronic
ADediting_1002465	chr22_43950681_+	intronic
ADediting_1002466	chr22_43950684_+	intronic
ADediting_1002467	chr22_43950686_+	intronic
ADediting_1002468	chr22_43950696_+	intronic
ADediting_1002469	chr22_43950703_+	intronic
ADediting_1002470	chr22_43950716_+	intronic
ADediting_1002471	chr22_43950717_+	intronic
ADediting_1002472	chr22_43950721_+	intronic
ADediting_1002473	chr22_43950729_+	intronic
ADediting_1002474	chr22_43950742_+	intronic
ADediting_1002475	chr22_43950743_+	intronic
ADediting_1002476	chr22_43950746_+	intronic
ADediting_1002477	chr22_43950752_+	intronic
ADediting_1002478	chr22_43950753_+	intronic
ADediting_1002479	chr22_43950756_+	intronic
ADediting_1002480	chr22_43950758_+	intronic
ADediting_1002481	chr22_43950774_+	intronic
ADediting_1002482	chr22_43950778_+	intronic
ADediting_1002483	chr22_43950782_+	intronic
ADediting_1002484	chr22_43950795_+	intronic
ADediting_1002485	chr22_43950801_+	intronic
ADediting_1002486	chr22_43950821_+	intronic
ADediting_1002487	chr22_43950833_+	intronic
ADediting_1002488	chr22_43950834_+	intronic
ADediting_1002489	chr22_43950846_+	intronic
ADediting_1002490	chr22_43950847_+	intronic
ADediting_1002491	chr22_43950851_+	intronic
ADediting_1002492	chr22_43950873_+	intronic
ADediting_1002493	chr22_43950874_+	intronic
ADediting_1002494	chr22_43950880_+	intronic
ADediting_1002495	chr22_43950886_+	intronic
ADediting_1002496	chr22_43950902_+	intronic
ADediting_1002497	chr22_43951043_+	intronic
ADediting_1002498	chr22_43951061_+	intronic
ADediting_1002499	chr22_43951062_+	intronic
ADediting_1002500	chr22_43951067_+	intronic
ADediting_1002501	chr22_43951088_+	intronic
ADediting_1002502	chr22_43951094_+	intronic
ADediting_1002503	chr22_43951097_+	intronic
ADediting_1002504	chr22_43951101_+	intronic
ADediting_1002505	chr22_43951102_+	intronic
ADediting_1002506	chr22_43951106_+	intronic
ADediting_1002507	chr22_43951137_+	intronic
ADediting_1002508	chr22_43951143_+	intronic
ADediting_1002509	chr22_43951146_+	intronic
ADediting_1002510	chr22_43951147_+	intronic
ADediting_1002511	chr22_43951148_+	intronic
ADediting_1002512	chr22_43951149_+	intronic
ADediting_1002513	chr22_43951151_+	intronic
ADediting_1002514	chr22_43951156_+	intronic
ADediting_1002515	chr22_43951158_+	intronic
ADediting_1002516	chr22_43951159_+	intronic
ADediting_1002517	chr22_43951162_+	intronic
ADediting_1002518	chr22_43951170_+	intronic
ADediting_1002519	chr22_43951188_+	intronic
ADediting_1002520	chr22_43951189_+	intronic
ADediting_1002521	chr22_43951194_+	intronic
ADediting_1002522	chr22_43951201_+	intronic
ADediting_1002523	chr22_43951211_+	intronic
ADediting_1002524	chr22_43951215_+	intronic
ADediting_1002525	chr22_43951218_+	intronic
ADediting_1002526	chr22_43951220_+	intronic
ADediting_1002527	chr22_43951224_+	intronic
ADediting_1002528	chr22_43951229_+	intronic
ADediting_1002529	chr22_43951230_+	intronic
ADediting_1002530	chr22_43951234_+	intronic
ADediting_1002531	chr22_43951237_+	intronic
ADediting_1002532	chr22_43951250_+	intronic
ADediting_1002533	chr22_43951276_+	intronic
ADediting_1571284	chr22_43947109_+	UTR3
ADediting_1571285	chr22_43947163_+	UTR3
ADediting_1571286	chr22_43947180_+	UTR3
ADediting_1571287	chr22_43947181_+	UTR3
ADediting_1571288	chr22_43949492_+	intronic
ADediting_1571289	chr22_43949685_+	intronic
ADediting_1571290	chr22_43949808_+	intronic
ADediting_1571291	chr22_43949852_+	intronic
ADediting_1571292	chr22_43949885_+	intronic
ADediting_1571293	chr22_43949907_+	intronic
ADediting_1571294	chr22_43949922_+	intronic
ADediting_1571295	chr22_43949951_+	intronic
ADediting_1571296	chr22_43949952_+	intronic
ADediting_1571297	chr22_43950017_+	intronic
ADediting_1571298	chr22_43950156_+	intronic
ADediting_1571299	chr22_43950872_+	intronic
ADediting_1571300	chr22_43951150_+	intronic
ADediting_1571301	chr22_43951221_+	intronic
ADediting_1642945	chr22_43960528_+	intronic

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_1002340	chr22_43924855_+	SINE	Alu	Name=AluY
ADediting_1002341	chr22_43929858_+	SINE	Alu	Name=AluSx1
ADediting_1002342	chr22_43929859_+	SINE	Alu	Name=AluSx1
ADediting_1002343	chr22_43929871_+	SINE	Alu	Name=AluSx1
ADediting_1002344	chr22_43930942_+	SINE	Alu	Name=AluY
ADediting_1002345	chr22_43931072_+	SINE	Alu	Name=AluY
ADediting_1002346	chr22_43933499_+	SINE	Alu	Name=AluJr
ADediting_1002347	chr22_43933609_+	SINE	Alu	Name=AluJr
ADediting_1002348	chr22_43933621_+	SINE	Alu	Name=AluJr
ADediting_1002349	chr22_43934084_+	SINE	Alu	Name=AluSx1
ADediting_1002350	chr22_43934088_+	SINE	Alu	Name=AluSx1
ADediting_1002351	chr22_43934097_+	SINE	Alu	Name=AluSx1
ADediting_1002352	chr22_43934102_+	SINE	Alu	Name=AluSx1
ADediting_1002353	chr22_43934196_+	SINE	Alu	Name=AluSx1
ADediting_1002354	chr22_43934223_+	SINE	Alu	Name=AluSx1
ADediting_1002355	chr22_43934296_+	SINE	Alu	Name=AluSx1
ADediting_1002356	chr22_43939178_+	SINE	Alu	Name=AluSz
ADediting_1002357	chr22_43939741_+	SINE	Alu	Name=AluSq2
ADediting_1002358	chr22_43940885_+	SINE	Alu	Name=AluSg
ADediting_1002359	chr22_43940929_+	SINE	Alu	Name=AluSg
ADediting_1002360	chr22_43943845_+	SINE	Alu	Name=AluSg
ADediting_1002361	chr22_43943858_+	SINE	Alu	Name=AluSg
ADediting_1002362	chr22_43943906_+	SINE	Alu	Name=AluSg
ADediting_1002363	chr22_43943946_+	SINE	Alu	Name=AluSg
ADediting_1002364	chr22_43943954_+	SINE	Alu	Name=AluSg
ADediting_1002365	chr22_43943972_+	SINE	Alu	Name=AluSg
ADediting_1002366	chr22_43943997_+	SINE	Alu	Name=AluSg
ADediting_1002367	chr22_43944047_+	SINE	Alu	Name=AluSg
ADediting_1002368	chr22_43944048_+	SINE	Alu	Name=AluSg
ADediting_1002369	chr22_43944060_+	SINE	Alu	Name=AluSg
ADediting_1002370	chr22_43947103_+	SINE	Alu	Name=AluSp
ADediting_1002371	chr22_43947104_+	SINE	Alu	Name=AluSp
ADediting_1002372	chr22_43947125_+	SINE	Alu	Name=AluSp
ADediting_1002373	chr22_43947134_+	SINE	Alu	Name=AluSp
ADediting_1002374	chr22_43947144_+	SINE	Alu	Name=AluSp
ADediting_1002375	chr22_43947149_+	SINE	Alu	Name=AluSp
ADediting_1002376	chr22_43947157_+	SINE	Alu	Name=AluSp
ADediting_1002377	chr22_43947158_+	SINE	Alu	Name=AluSp
ADediting_1002378	chr22_43947173_+	SINE	Alu	Name=AluSp
ADediting_1002379	chr22_43947177_+	SINE	Alu	Name=AluSp
ADediting_1002380	chr22_43947182_+	SINE	Alu	Name=AluSp
ADediting_1002381	chr22_43947183_+	SINE	Alu	Name=AluSp
ADediting_1002382	chr22_43947203_+	SINE	Alu	Name=AluSp
ADediting_1002383	chr22_43947208_+	SINE	Alu	Name=AluSp
ADediting_1002384	chr22_43947220_+	SINE	Alu	Name=AluSp
ADediting_1002385	chr22_43947238_+	SINE	Alu	Name=AluSp
ADediting_1002386	chr22_43947239_+	SINE	Alu	Name=AluSp
ADediting_1002387	chr22_43947244_+	SINE	Alu	Name=AluSp
ADediting_1002388	chr22_43947265_+	SINE	Alu	Name=AluSp
ADediting_1002389	chr22_43947274_+	SINE	Alu	Name=AluSp
ADediting_1002390	chr22_43947280_+	SINE	Alu	Name=AluSp
ADediting_1002391	chr22_43947284_+	SINE	Alu	Name=AluSp
ADediting_1002392	chr22_43947287_+	SINE	Alu	Name=AluSp
ADediting_1002393	chr22_43947316_+	SINE	Alu	Name=AluSp
ADediting_1002396	chr22_43949335_+	SINE	Alu	Name=AluSp
ADediting_1002397	chr22_43949380_+	SINE	Alu	Name=AluSp
ADediting_1002398	chr22_43949387_+	SINE	Alu	Name=AluSp
ADediting_1002399	chr22_43949390_+	SINE	Alu	Name=AluSp
ADediting_1002400	chr22_43949393_+	SINE	Alu	Name=AluSp
ADediting_1002401	chr22_43949398_+	SINE	Alu	Name=AluSp
ADediting_1002402	chr22_43949400_+	SINE	Alu	Name=AluSp
ADediting_1002403	chr22_43949401_+	SINE	Alu	Name=AluSp
ADediting_1002404	chr22_43949414_+	SINE	Alu	Name=AluSp
ADediting_1002405	chr22_43949416_+	SINE	Alu	Name=AluSp
ADediting_1002406	chr22_43949417_+	SINE	Alu	Name=AluSp
ADediting_1002407	chr22_43949436_+	SINE	Alu	Name=AluSp
ADediting_1002408	chr22_43949437_+	SINE	Alu	Name=AluSp
ADediting_1002409	chr22_43949438_+	SINE	Alu	Name=AluSp
ADediting_1002410	chr22_43949490_+	SINE	Alu	Name=AluSp
ADediting_1002411	chr22_43949496_+	SINE	Alu	Name=AluSp
ADediting_1002412	chr22_43949506_+	SINE	Alu	Name=AluSp
ADediting_1002413	chr22_43949512_+	SINE	Alu	Name=AluSp
ADediting_1002414	chr22_43949516_+	SINE	Alu	Name=AluSp
ADediting_1002415	chr22_43949517_+	SINE	Alu	Name=AluSp
ADediting_1002416	chr22_43949526_+	SINE	Alu	Name=AluSp
ADediting_1002417	chr22_43949532_+	SINE	Alu	Name=AluSp
ADediting_1002418	chr22_43949535_+	SINE	Alu	Name=AluSp
ADediting_1002419	chr22_43949561_+	SINE	Alu	Name=AluSp
ADediting_1002420	chr22_43949567_+	SINE	Alu	Name=AluSp
ADediting_1002421	chr22_43949586_+	SINE	Alu	Name=AluSp
ADediting_1002422	chr22_43949588_+	SINE	Alu	Name=AluSp
ADediting_1002423	chr22_43949595_+	SINE	Alu	Name=AluSp
ADediting_1002424	chr22_43949613_+	SINE	Alu	Name=AluSp
ADediting_1002425	chr22_43949614_+	SINE	Alu	Name=AluSp
ADediting_1002426	chr22_43949635_+	SINE	Alu	Name=AluSp
ADediting_1002427	chr22_43949642_+	SINE	Alu	Name=AluSp
ADediting_1002428	chr22_43949816_+	SINE	Alu	Name=AluSx1
ADediting_1002429	chr22_43949817_+	SINE	Alu	Name=AluSx1
ADediting_1002430	chr22_43949822_+	SINE	Alu	Name=AluSx1
ADediting_1002431	chr22_43949838_+	SINE	Alu	Name=AluSx1
ADediting_1002432	chr22_43949847_+	SINE	Alu	Name=AluSx1
ADediting_1002433	chr22_43949857_+	SINE	Alu	Name=AluSx1
ADediting_1002434	chr22_43949862_+	SINE	Alu	Name=AluSx1
ADediting_1002435	chr22_43949875_+	SINE	Alu	Name=AluSx1
ADediting_1002436	chr22_43949876_+	SINE	Alu	Name=AluSx1
ADediting_1002437	chr22_43949886_+	SINE	Alu	Name=AluSx1
ADediting_1002438	chr22_43949895_+	SINE	Alu	Name=AluSx1
ADediting_1002439	chr22_43949896_+	SINE	Alu	Name=AluSx1
ADediting_1002440	chr22_43949910_+	SINE	Alu	Name=AluSx1
ADediting_1002441	chr22_43949911_+	SINE	Alu	Name=AluSx1
ADediting_1002442	chr22_43949912_+	SINE	Alu	Name=AluSx1
ADediting_1002443	chr22_43949916_+	SINE	Alu	Name=AluSx1
ADediting_1002444	chr22_43949919_+	SINE	Alu	Name=AluSx1
ADediting_1002445	chr22_43949920_+	SINE	Alu	Name=AluSx1
ADediting_1002446	chr22_43949921_+	SINE	Alu	Name=AluSx1
ADediting_1002447	chr22_43949925_+	SINE	Alu	Name=AluSx1
ADediting_1002448	chr22_43949929_+	SINE	Alu	Name=AluSx1
ADediting_1002449	chr22_43949997_+	SINE	Alu	Name=AluSx1
ADediting_1002450	chr22_43950013_+	SINE	Alu	Name=AluSx1
ADediting_1002451	chr22_43950153_+	SINE	Alu	Name=AluJo
ADediting_1002452	chr22_43950159_+	SINE	Alu	Name=AluJo
ADediting_1002453	chr22_43950173_+	SINE	Alu	Name=AluJo
ADediting_1002454	chr22_43950178_+	SINE	Alu	Name=AluJo
ADediting_1002455	chr22_43950187_+	SINE	Alu	Name=AluJo
ADediting_1002456	chr22_43950207_+	SINE	Alu	Name=AluJo
ADediting_1002457	chr22_43950208_+	SINE	Alu	Name=AluJo
ADediting_1002458	chr22_43950211_+	SINE	Alu	Name=AluJo
ADediting_1002459	chr22_43950225_+	Retroposon	SVA	Name=SVA_F,AluJo
ADediting_1002460	chr22_43950233_+	Retroposon	SVA	Name=SVA_F,AluJo
ADediting_1002461	chr22_43950234_+	SINE	Alu	Name=AluJo,SVA_F
ADediting_1002462	chr22_43950636_+	SINE	Alu	Name=AluJo
ADediting_1002463	chr22_43950665_+	SINE	Alu	Name=AluJo
ADediting_1002464	chr22_43950670_+	SINE	Alu	Name=AluJo
ADediting_1002465	chr22_43950681_+	SINE	Alu	Name=AluJo
ADediting_1002466	chr22_43950684_+	SINE	Alu	Name=AluJo
ADediting_1002467	chr22_43950686_+	SINE	Alu	Name=AluJo
ADediting_1002468	chr22_43950696_+	SINE	Alu	Name=AluJo
ADediting_1002469	chr22_43950703_+	SINE	Alu	Name=AluJo
ADediting_1002470	chr22_43950716_+	SINE	Alu	Name=AluJo
ADediting_1002471	chr22_43950717_+	SINE	Alu	Name=AluJo
ADediting_1002472	chr22_43950721_+	SINE	Alu	Name=AluJo
ADediting_1002473	chr22_43950729_+	SINE	Alu	Name=AluJo
ADediting_1002474	chr22_43950742_+	SINE	Alu	Name=AluJo
ADediting_1002475	chr22_43950743_+	SINE	Alu	Name=AluJo
ADediting_1002476	chr22_43950746_+	SINE	Alu	Name=AluJo
ADediting_1002477	chr22_43950752_+	SINE	Alu	Name=AluJo
ADediting_1002478	chr22_43950753_+	SINE	Alu	Name=AluJo
ADediting_1002479	chr22_43950756_+	SINE	Alu	Name=AluJo
ADediting_1002480	chr22_43950758_+	SINE	Alu	Name=AluJo
ADediting_1002481	chr22_43950774_+	SINE	Alu	Name=AluJo
ADediting_1002482	chr22_43950778_+	SINE	Alu	Name=AluJo
ADediting_1002483	chr22_43950782_+	SINE	Alu	Name=AluJo
ADediting_1002484	chr22_43950795_+	SINE	Alu	Name=AluJo
ADediting_1002485	chr22_43950801_+	SINE	Alu	Name=AluJo
ADediting_1002486	chr22_43950821_+	SINE	Alu	Name=AluJo
ADediting_1002487	chr22_43950833_+	SINE	Alu	Name=AluJo
ADediting_1002488	chr22_43950834_+	SINE	Alu	Name=AluJo
ADediting_1002489	chr22_43950846_+	SINE	Alu	Name=AluJo
ADediting_1002490	chr22_43950847_+	SINE	Alu	Name=AluJo
ADediting_1002491	chr22_43950851_+	SINE	Alu	Name=AluJo
ADediting_1002492	chr22_43950873_+	SINE	Alu	Name=AluJo
ADediting_1002493	chr22_43950874_+	SINE	Alu	Name=AluJo
ADediting_1002494	chr22_43950880_+	SINE	Alu	Name=AluJo
ADediting_1002495	chr22_43950886_+	SINE	Alu	Name=AluJo
ADediting_1002496	chr22_43950902_+	SINE	Alu	Name=AluJo
ADediting_1002497	chr22_43951043_+	SINE	Alu	Name=AluSx1
ADediting_1002498	chr22_43951061_+	SINE	Alu	Name=AluSx1
ADediting_1002499	chr22_43951062_+	SINE	Alu	Name=AluSx1
ADediting_1002500	chr22_43951067_+	SINE	Alu	Name=AluSx1
ADediting_1002501	chr22_43951088_+	SINE	Alu	Name=AluSx1
ADediting_1002502	chr22_43951094_+	SINE	Alu	Name=AluSx1
ADediting_1002503	chr22_43951097_+	SINE	Alu	Name=AluSx1
ADediting_1002504	chr22_43951101_+	SINE	Alu	Name=AluSx1
ADediting_1002505	chr22_43951102_+	SINE	Alu	Name=AluSx1
ADediting_1002506	chr22_43951106_+	SINE	Alu	Name=AluSx1
ADediting_1002507	chr22_43951137_+	SINE	Alu	Name=AluSx1
ADediting_1002508	chr22_43951143_+	SINE	Alu	Name=AluSx1
ADediting_1002509	chr22_43951146_+	SINE	Alu	Name=AluSx1
ADediting_1002510	chr22_43951147_+	SINE	Alu	Name=AluSx1
ADediting_1002511	chr22_43951148_+	SINE	Alu	Name=AluSx1
ADediting_1002512	chr22_43951149_+	SINE	Alu	Name=AluSx1
ADediting_1002513	chr22_43951151_+	SINE	Alu	Name=AluSx1
ADediting_1002514	chr22_43951156_+	SINE	Alu	Name=AluSx1
ADediting_1002515	chr22_43951158_+	SINE	Alu	Name=AluSx1
ADediting_1002516	chr22_43951159_+	SINE	Alu	Name=AluSx1
ADediting_1002517	chr22_43951162_+	SINE	Alu	Name=AluSx1
ADediting_1002518	chr22_43951170_+	SINE	Alu	Name=AluSx1
ADediting_1002519	chr22_43951188_+	SINE	Alu	Name=AluSx1
ADediting_1002520	chr22_43951189_+	SINE	Alu	Name=AluSx1
ADediting_1002521	chr22_43951194_+	SINE	Alu	Name=AluSx1
ADediting_1002522	chr22_43951201_+	SINE	Alu	Name=AluSx1
ADediting_1002523	chr22_43951211_+	SINE	Alu	Name=AluSx1
ADediting_1002524	chr22_43951215_+	SINE	Alu	Name=AluSx1
ADediting_1002525	chr22_43951218_+	SINE	Alu	Name=AluSx1
ADediting_1002526	chr22_43951220_+	SINE	Alu	Name=AluSx1
ADediting_1002527	chr22_43951224_+	SINE	Alu	Name=AluSx1
ADediting_1002528	chr22_43951229_+	SINE	Alu	Name=AluSx1
ADediting_1002529	chr22_43951230_+	SINE	Alu	Name=AluSx1
ADediting_1002530	chr22_43951234_+	SINE	Alu	Name=AluSx1
ADediting_1002531	chr22_43951237_+	SINE	Alu	Name=AluSx1
ADediting_1002532	chr22_43951250_+	SINE	Alu	Name=AluSx1
ADediting_1002533	chr22_43951276_+	SINE	Alu	Name=AluSx1
ADediting_1571284	chr22_43947109_+	SINE	Alu	Name=AluSp
ADediting_1571285	chr22_43947163_+	SINE	Alu	Name=AluSp
ADediting_1571286	chr22_43947180_+	SINE	Alu	Name=AluSp
ADediting_1571287	chr22_43947181_+	SINE	Alu	Name=AluSp
ADediting_1571288	chr22_43949492_+	SINE	Alu	Name=AluSp
ADediting_1571290	chr22_43949808_+	SINE	Alu	Name=AluSx1
ADediting_1571291	chr22_43949852_+	SINE	Alu	Name=AluSx1
ADediting_1571292	chr22_43949885_+	SINE	Alu	Name=AluSx1
ADediting_1571293	chr22_43949907_+	SINE	Alu	Name=AluSx1
ADediting_1571294	chr22_43949922_+	SINE	Alu	Name=AluSx1
ADediting_1571295	chr22_43949951_+	SINE	Alu	Name=AluSx1
ADediting_1571296	chr22_43949952_+	SINE	Alu	Name=AluSx1
ADediting_1571297	chr22_43950017_+	SINE	Alu	Name=AluSx1
ADediting_1571298	chr22_43950156_+	SINE	Alu	Name=AluJo
ADediting_1571299	chr22_43950872_+	SINE	Alu	Name=AluJo
ADediting_1571300	chr22_43951150_+	SINE	Alu	Name=AluSx1
ADediting_1571301	chr22_43951221_+	SINE	Alu	Name=AluSx1
ADediting_1642945	chr22_43960528_+	SINE	Alu	Name=AluSx

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RNA A-to-I editing events in the alternative splicing sites for PNPLA3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PNPLA3

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

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Protein coding region RNA A-to-I editings for PNPLA3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for PNPLA3

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1002370	chr22_43947103_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-638	chr22	43947102	43947108	7mer-1a	43947084	43947108	157	-30.65
ADediting_1002372	chr22_43947125_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-3150a-5p	chr22	43947123	43947129	7mer-m8	43947112	43947130	148	-24.65
ADediting_1002372	chr22_43947125_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-3150b-5p	chr22	43947123	43947129	7mer-m8	43947112	43947130	151	-25.5
ADediting_1002373	chr22_43947134_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6084	chr22	43947129	43947135	7mer-m8	43947118	43947136	160	-28.77
ADediting_1002374	chr22_43947144_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4726-3p	chr22	43947138	43947144	7mer-m8	43947123	43947145	150	-21.38
ADediting_1002377	chr22_43947158_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-12113	chr22	43947151	43947157	7mer-m8	43947138	43947158	147	-19.86
ADediting_1002377	chr22_43947158_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4539	chr22	43947151	43947157	7mer-m8	43947139	43947158	151	-20
ADediting_1002378	chr22_43947173_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-3190-5p	chr22	43947166	43947172	7mer-m8	43947154	43947173	152	-19.64
ADediting_1002379	chr22_43947177_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4659a-5p	chr22	43947173	43947180	8mer-1a	43947159	43947180	145	-13.59
ADediting_1002379	chr22_43947177_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4659b-5p	chr22	43947173	43947180	8mer-1a	43947162	43947180	145	-15.59
ADediting_1002379	chr22_43947177_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4716-5p	chr22	43947171	43947177	7mer-m8	43947157	43947178	140	-10.69
ADediting_1002379	chr22_43947177_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4776-3p	chr22	43947174	43947181	8mer-1a	43947158	43947181	163	-21.31
ADediting_1002380	chr22_43947182_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1182	chr22	43947180	43947186	7mer-m8	43947165	43947187	151	-18.9
ADediting_1002380	chr22_43947182_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-193a-5p	chr22	43947179	43947185	7mer-m8	43947161	43947186	151	-23.42
ADediting_1002380	chr22_43947182_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-431-5p	chr22	43947177	43947183	7mer-m8	43947164	43947184	140	-15.81
ADediting_1002381	chr22_43947183_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1251-3p	chr22	43947177	43947183	7mer-m8	43947164	43947184	145	-17.25
ADediting_1002381	chr22_43947183_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-3158-3p	chr22	43947180	43947186	7mer-m8	43947167	43947187	146	-16.16
ADediting_1002382	chr22_43947203_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-153-5p	chr22	43947196	43947202	7mer-m8	43947183	43947203	146	-9.95
ADediting_1002382	chr22_43947203_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-3680-3p	chr22	43947200	43947207	8mer-1a	43947185	43947207	140	-13.99
ADediting_1002383	chr22_43947208_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6844	chr22	43947202	43947208	7mer-m8	43947188	43947209	155	-7.49
ADediting_1002385	chr22_43947238_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-513a-5p	chr22	43947232	43947238	7mer-m8	43947222	43947239	152	-17.76
ADediting_1002385	chr22_43947238_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-638	chr22	43947237	43947243	7mer-1a	43947219	43947243	155	-31.88
ADediting_1002386	chr22_43947239_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-8052	chr22	43947237	43947243	7mer-1a	43947225	43947243	143	-23.66
ADediting_1002390	chr22_43947280_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-10400-3p	chr22	43947277	43947283	7mer-m8	43947263	43947284	140	-21.46
ADediting_1002390	chr22_43947280_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4437	chr22	43947276	43947283	8mer-1a	43947263	43947283	146	-19.6
ADediting_1002390	chr22_43947280_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4674	chr22	43947277	43947283	7mer-m8	43947264	43947284	147	-22.8
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-331-3p	chr22	43947281	43947287	7mer-m8	43947268	43947288	145	-20.27
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4292	chr22	43947280	43947286	7mer-m8	43947270	43947287	140	-21.97
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4313	chr22	43947283	43947289	7mer-m8	43947271	43947290	156	-21.89
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6791-5p	chr22	43947280	43947286	7mer-m8	43947266	43947287	142	-25.96
ADediting_1002393	chr22_43947316_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-652-3p	chr22	43947313	43947319	7mer-m8	43947299	43947320	150	-15.8
ADediting_1002394	chr22_43947425_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4485-5p	chr22	43947419	43947425	7mer-m8	43947411	43947426	140	-14.78
ADediting_1571284	chr22_43947109_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-371a-3p	chr22	43947107	43947113	7mer-m8	43947092	43947114	144	-17.24
ADediting_1571287	chr22_43947181_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-152-5p	chr22	43947178	43947184	7mer-m8	43947163	43947185	148	-16.91

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1002370	chr22_43947103_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-10399-5p	chr22	43947098	43947104	7mer-m8	43947084	43947105	152	-12.5
ADediting_1002370	chr22_43947103_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6504-3p	chr22	43947098	43947104	7mer-m8	43947084	43947105	149	-16.94
ADediting_1002371	chr22_43947104_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-10399-5p	chr22	43947098	43947104	7mer-m8	43947084	43947105	152	-12.5
ADediting_1002371	chr22_43947104_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-5089-5p	chr22	43947102	43947108	7mer-m8	43947089	43947109	144	-15.34
ADediting_1002371	chr22_43947104_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6504-3p	chr22	43947098	43947104	7mer-m8	43947084	43947105	149	-16.94
ADediting_1002372	chr22_43947125_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6878-3p	chr22	43947118	43947125	8mer-1a	43947105	43947125	142	-14.14
ADediting_1002373	chr22_43947134_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4727-5p	chr22	43947129	43947135	7mer-m8	43947116	43947136	152	-20.56
ADediting_1002378	chr22_43947173_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4781-3p	chr22	43947169	43947176	8mer-1a	43947153	43947176	142	-12.32
ADediting_1002380	chr22_43947182_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19a-5p	chr22	43947177	43947183	7mer-m8	43947163	43947184	152	-11.8
ADediting_1002380	chr22_43947182_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-1-5p	chr22	43947177	43947183	7mer-m8	43947161	43947184	155	-14.66
ADediting_1002380	chr22_43947182_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-2-5p	chr22	43947177	43947183	7mer-m8	43947162	43947184	155	-11.64
ADediting_1002381	chr22_43947183_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19a-5p	chr22	43947177	43947183	7mer-m8	43947163	43947184	152	-11.8
ADediting_1002381	chr22_43947183_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-1-5p	chr22	43947177	43947183	7mer-m8	43947161	43947184	155	-14.66
ADediting_1002381	chr22_43947183_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-2-5p	chr22	43947177	43947183	7mer-m8	43947162	43947184	155	-11.64
ADediting_1002381	chr22_43947183_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6823-5p	chr22	43947181	43947187	7mer-m8	43947168	43947188	143	-17.2
ADediting_1002384	chr22_43947220_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6872-3p	chr22	43947216	43947222	7mer-m8	43947203	43947223	141	-12.32
ADediting_1002385	chr22_43947238_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-10399-5p	chr22	43947233	43947239	7mer-m8	43947219	43947240	148	-10.96
ADediting_1002385	chr22_43947238_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6504-3p	chr22	43947233	43947239	7mer-m8	43947216	43947240	148	-14.06
ADediting_1002385	chr22_43947238_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-7151-3p	chr22	43947231	43947238	8mer-1a	43947217	43947238	143	-13.53
ADediting_1002386	chr22_43947239_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-10399-5p	chr22	43947233	43947239	7mer-m8	43947219	43947240	148	-10.96
ADediting_1002386	chr22_43947239_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-5089-5p	chr22	43947237	43947243	7mer-m8	43947224	43947244	152	-18.63
ADediting_1002386	chr22_43947239_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6504-3p	chr22	43947233	43947239	7mer-m8	43947216	43947240	148	-14.06
ADediting_1002387	chr22_43947244_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-5089-5p	chr22	43947237	43947243	7mer-m8	43947224	43947244	152	-18.63
ADediting_1002387	chr22_43947244_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6506-5p	chr22	43947238	43947244	7mer-m8	43947223	43947245	144	-16.07
ADediting_1002388	chr22_43947265_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1976	chr22	43947262	43947269	8mer-1a	43947248	43947269	152	-24.28
ADediting_1002388	chr22_43947265_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6747-3p	chr22	43947260	43947267	8mer-1a	43947247	43947267	148	-22.77
ADediting_1002389	chr22_43947274_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-8062	chr22	43947269	43947275	7mer-m8	43947256	43947276	141	-10.43
ADediting_1002391	chr22_43947284_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1343-3p	chr22	43947280	43947286	7mer-m8	43947264	43947287	143	-22.21
ADediting_1002391	chr22_43947284_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6742-3p	chr22	43947279	43947286	8mer-1a	43947267	43947286	145	-14.93
ADediting_1002391	chr22_43947284_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6783-3p	chr22	43947280	43947286	7mer-m8	43947267	43947287	146	-16.82
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1281	chr22	43947284	43947290	7mer-m8	43947275	43947291	145	-17.85
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1343-3p	chr22	43947280	43947286	7mer-m8	43947264	43947287	143	-22.21
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6783-3p	chr22	43947280	43947286	7mer-m8	43947267	43947287	146	-16.82
ADediting_1002392	chr22_43947287_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6829-3p	chr22	43947283	43947289	7mer-m8	43947271	43947290	144	-18.45
ADediting_1002394	chr22_43947425_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-1976	chr22	43947422	43947428	7mer-m8	43947410	43947429	145	-20.88
ADediting_1002394	chr22_43947425_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6747-3p	chr22	43947420	43947427	8mer-1a	43947407	43947427	140	-17.42
ADediting_1571284	chr22_43947109_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-5089-5p	chr22	43947102	43947108	7mer-m8	43947089	43947109	144	-15.34
ADediting_1571284	chr22_43947109_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-512-3p	chr22	43947107	43947113	7mer-m8	43947090	43947114	154	-20.81
ADediting_1571284	chr22_43947109_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-6506-5p	chr22	43947103	43947109	7mer-m8	43947087	43947110	146	-17.21
ADediting_1571285	chr22_43947163_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-3663-5p	chr22	43947157	43947163	7mer-m8	43947148	43947164	141	-17.54
ADediting_1571285	chr22_43947163_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4463	chr22	43947160	43947166	7mer-m8	43947151	43947167	143	-16.16
ADediting_1571285	chr22_43947163_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-4494	chr22	43947161	43947167	7mer-m8	43947147	43947168	146	-18.82
ADediting_1571286	chr22_43947180_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19a-5p	chr22	43947177	43947183	7mer-m8	43947163	43947184	152	-11.8
ADediting_1571286	chr22_43947180_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-1-5p	chr22	43947177	43947183	7mer-m8	43947161	43947184	155	-14.66
ADediting_1571286	chr22_43947180_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-2-5p	chr22	43947177	43947183	7mer-m8	43947162	43947184	155	-11.64
ADediting_1571287	chr22_43947181_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19a-5p	chr22	43947177	43947183	7mer-m8	43947163	43947184	152	-11.8
ADediting_1571287	chr22_43947181_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-1-5p	chr22	43947177	43947183	7mer-m8	43947161	43947184	155	-14.66
ADediting_1571287	chr22_43947181_+	ENSG00000100344.11	ENST00000216180.8	PNPLA3-201	hsa-miR-19b-2-5p	chr22	43947177	43947183	7mer-m8	43947162	43947184	155	-11.64

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_291761

chr11_93733708_-

ENSG00000100344.11

ENST00000216180.8

PNPLA3-201

hsa-miR-1304-3p

chr22

43947034

43947041

8mer-1a

43947018

43947041

142

-14.29

ADediting_291761

chr11_93733708_-

ENSG00000100344.11

ENST00000216180.8

PNPLA3-201

hsa-miR-1304-3p

chr22

43947518

43947524

7mer-m8

43947504

43947525

140

-14.65

ADediting_291761

chr11_93733708_-

ENSG00000100344.11

ENST00000423180.2

PNPLA3-203

hsa-miR-1304-3p

chr22

43947034

43947041

8mer-1a

43947018

43947041

142

-14.29

Differentially expressed gene-miRNA network

Differentially expressed mRNA-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for PNPLA3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000216180.8	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_1002370	ENST00000216180.8	chr22_43947103_+	2274	-1010.90	-1011.60	-1038.30
ADediting_1002371	ENST00000216180.8	chr22_43947104_+	2275	-1011.60	-1011.60	-1038.30
ADediting_1571284	ENST00000216180.8	chr22_43947109_+	2280	-1010.80	-1011.60	-1038.30
ADediting_1002372	ENST00000216180.8	chr22_43947125_+	2296	-1011.30	-1011.60	-1038.30
ADediting_1002373	ENST00000216180.8	chr22_43947134_+	2305	-1010.90	-1011.60	-1038.30
ADediting_1002374	ENST00000216180.8	chr22_43947144_+	2315	-1010.60	-1011.60	-1038.30
ADediting_1002375	ENST00000216180.8	chr22_43947149_+	2320	-1011.80	-1011.60	-1038.30
ADediting_1002376	ENST00000216180.8	chr22_43947157_+	2328	-1011.60	-1011.60	-1038.30
ADediting_1002377	ENST00000216180.8	chr22_43947158_+	2329	-1012.30	-1011.60	-1038.30
ADediting_1571285	ENST00000216180.8	chr22_43947163_+	2334	-1011.60	-1011.60	-1038.30
ADediting_1002378	ENST00000216180.8	chr22_43947173_+	2344	-1012.60	-1011.60	-1038.30
ADediting_1002379	ENST00000216180.8	chr22_43947177_+	2348	-1015.20	-1011.60	-1038.30
ADediting_1571286	ENST00000216180.8	chr22_43947180_+	2351	-1011.60	-1011.60	-1038.30
ADediting_1571287	ENST00000216180.8	chr22_43947181_+	2352	-1014.80	-1011.60	-1038.30
ADediting_1002380	ENST00000216180.8	chr22_43947182_+	2353	-1014.80	-1011.60	-1038.30
ADediting_1002381	ENST00000216180.8	chr22_43947183_+	2354	-1011.30	-1011.60	-1038.30
ADediting_1002382	ENST00000216180.8	chr22_43947203_+	2374	-1011.60	-1011.60	-1038.30
ADediting_1002383	ENST00000216180.8	chr22_43947208_+	2379	-1014.80	-1011.60	-1038.30
ADediting_1002384	ENST00000216180.8	chr22_43947220_+	2391	-1011.20	-1011.60	-1038.30
ADediting_1002385	ENST00000216180.8	chr22_43947238_+	2409	-1013.60	-1011.60	-1038.30
ADediting_1002386	ENST00000216180.8	chr22_43947239_+	2410	-1012.20	-1011.60	-1038.30
ADediting_1002387	ENST00000216180.8	chr22_43947244_+	2415	-1012.60	-1011.60	-1038.30
ADediting_1002388	ENST00000216180.8	chr22_43947265_+	2436	-1011.90	-1011.60	-1038.30
ADediting_1002389	ENST00000216180.8	chr22_43947274_+	2445	-1012.20	-1011.60	-1038.30
ADediting_1002390	ENST00000216180.8	chr22_43947280_+	2451	-1012.80	-1011.60	-1038.30
ADediting_1002391	ENST00000216180.8	chr22_43947284_+	2455	-1011.60	-1011.60	-1038.30
ADediting_1002392	ENST00000216180.8	chr22_43947287_+	2458	-1010.70	-1011.60	-1038.30
ADediting_1002393	ENST00000216180.8	chr22_43947316_+	2487	-1011.60	-1011.60	-1038.30
ADediting_1002394	ENST00000216180.8	chr22_43947425_+	2596	-1012.00	-1011.60	-1038.30

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for PNPLA3

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	ADediting_1002397	chr22_43949380_+	0.000499325325254182	0.196575812406796	0.133299402415676	0.0854525869436366	1.30148510499564e-11	0.372039455647294
DLPFC	ADediting_1002399	chr22_43949390_+	4.55638930841721e-05	0.229405455784687	0.0214423014997885	0.130604730270538	1.50865144957467e-09	0.334649166183073
DLPFC	ADediting_1002403	chr22_43949401_+	0.000540439313515492	0.195399147540076	0.151433135376377	0.0816671933679632	9.01581038842522e-10	0.338945617140687
DLPFC	ADediting_1002404	chr22_43949414_+	7.01003436250678e-06	0.252091867309466	0.00151916816837574	0.17936237350652	1.96781917830683e-08	0.312156831295458
DLPFC	ADediting_1002413	chr22_43949512_+	0.000276713859642607	0.205148946726134	0.127305664031386	0.0867906992735903	4.05822394624399e-10	0.345479851594871
DLPFC	ADediting_1002415	chr22_43949517_+	0.137209731900683	0.0846043982313372	0.917656040684733	-0.0058957382311582	1.66834462772241e-08	0.313659772006158
DLPFC	ADediting_1002416	chr22_43949526_+	0.00015934323778158	0.212861486868578	0.0327707829117647	0.121295026609443	7.88421738274581e-09	0.320380449717558
DLPFC	ADediting_1002417	chr22_43949532_+	0.000170054061210773	0.21196671050647	0.0154336732000469	0.137464266529619	2.8470803812327e-08	0.308763586597873
DLPFC	ADediting_1002431	chr22_43949838_+	0.00135442313573988	0.181208967520803	0.137993980794011	0.0844365283317412	1.7904306353673e-08	0.313017864675636
DLPFC	ADediting_1002432	chr22_43949847_+	0.000660333859339377	0.192388862568957	0.281682966437051	0.0613339183700648	4.73919795836204e-15	0.425332580439908
DLPFC	ADediting_1002434	chr22_43949862_+	3.67194056262661e-05	0.232137505206528	0.0252457054011041	0.127086070914159	8.28364471506908e-13	0.391682407264102
DLPFC	ADediting_1002436	chr22_43949876_+	0.0238704927523274	0.128301902173152	0.398115834831508	0.0481589642264308	4.32101182600755e-11	0.363050221766203
DLPFC	ADediting_1002441	chr22_43949911_+	0.256362825429297	0.0646590892514612	0.516941434709088	-0.0369444268412413	3.63828671082384e-10	0.346362349386976
DLPFC	ADediting_1002447	chr22_43949925_+	0.00197172143876645	0.175101047128988	0.236393337210263	0.0674453748181707	5.1948921240247e-10	0.343474662465202
DLPFC	ADediting_1002448	chr22_43949929_+	0.00160216481913033	0.178500663072081	0.121507425037403	0.0881324200312366	6.32164861946145e-10	0.341870344270181
DLPFC	ADediting_1002463	chr22_43950665_+	1.38588765292826e-07	0.293714342938709	2.9154206248802e-10	0.348143451051565	0.985941143216926	0.00100486903345047
DLPFC	ADediting_1002470	chr22_43950716_+	6.11347877172722e-08	0.301603495261512	7.55986000117282e-09	0.320752257559848	0.560218278388232	0.0332097926169398
DLPFC	ADediting_1002471	chr22_43950717_+	1.82363710258163e-07	0.291014318889115	9.31798287823128e-09	0.31889666255153	0.0126882859073723	0.141418007030765

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	1.84787010791864e-16	0.444701164619179	4.3424308900925e-12	0.380025707023586	4.54583368758334e-13	0.395793487952167
PCC	8.00336541742311e-13	0.488026862491358	7.85005181149051e-11	0.448302982345656	0.530159556488998	0.0456995430271054
CER	1.30774565043352e-11	0.516641745378828	0.000355111394039503	0.287814205699435	0.427432068987376	0.0652735468581345
TCX	3.67573379829386e-16	0.602041600481311	1.64713449756975e-07	0.411786023042815	0.538624200316652	-0.0505970445708863
FP	6.59953674635778e-05	0.294498819129399	2.55816008804097e-07	0.374734692278613	0.00118067226921994	0.241210779044009
IFG	0.0162518995470867	0.475652334529709	0.152498310399499	0.294840372028228	0.344110526027883	0.1974518513893
PG	2.08108847552685e-06	0.339828209770002	0.000586732409011355	0.249740014438344	0.916077573515063	0.00777885546437861
STG	2.91443912669202e-07	0.525181147075326	0.0115370234942829	0.274408179290491	0.0146070242136535	0.265616754629736

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Relation with AD stages for PNPLA3

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
TCX	ADediting_1002479	chr22_43950756_+	0.000326890647643597	-0.342430834088258
TCX	ADediting_1002481	chr22_43950774_+	0.000660320722886077	-0.325575833491367
TCX	ADediting_1002498	chr22_43951061_+	0.00171656871300369	-0.301004573980415

Correlation between AD stages and this gene's expression

Tissue

P-val

Coeff.

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RelatedDrugs for PNPLA3

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for PNPLA3

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
PNPLA3	C2750440	FATTY LIVER DISEASE, NONALCOHOLIC, SUSCEPTIBILITY TO, 1	4	UNIPROT
PNPLA3	C2750441	LIVER DISEASE, ALCOHOLIC, SUSCEPTIBILITY TO, 1	4	UNIPROT
PNPLA3	C0400966	Non-alcoholic Fatty Liver Disease	3	CTD_human
PNPLA3	C3241937	Nonalcoholic Steatohepatitis	3	CTD_human
PNPLA3	C0023891	Liver Cirrhosis, Alcoholic	2	CTD_human
PNPLA3	C0015695	Fatty Liver	1	CTD_human
PNPLA3	C0023896	Alcoholic Liver Diseases	1	CTD_human
PNPLA3	C2711227	Steatohepatitis	1	CTD_human

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Gene summary for PNPLA3

RNA A-to-I events for PNPLA3

RNA editing positional annotations for PNPLA3 using Annovar

RNA A-to-I editing events in the alternative splicing sites for PNPLA3

Differntial gene expression between RNA A-to-I edited versus non-edited samples for PNPLA3

Protein coding region RNA A-to-I editings for PNPLA3

The effects of the RNA editing to the miRNA binding sites for PNPLA3

The effects of the RNA editing to the stability of the RNA structures for PNPLA3

Relation with ADAR for PNPLA3

Relation with AD stages for PNPLA3

RelatedDrugs for PNPLA3

RelatedDiseases for PNPLA3

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene