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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ITPKC |
 Gene summary |
| Gene information | Gene symbol | ITPKC | Gene ID | 80271 |
| Gene name | inositol-trisphosphate 3-kinase C | |
| Synonyms | IP3-3KC|IP3KC | |
| Cytomap | 19q13.2 | |
| Type of gene | protein-coding | |
| Description | inositol-trisphosphate 3-kinase CIP3 3-kinase CIP3K CInsP 3 kinase Cinositol 1,4,5-trisphosphate 3-kinase CinsP 3-kinase C | |
| Modification date | 20200313 | |
| UniProtAcc | Q96DU7, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for ITPKC |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_752725(40719589, +), ADediting_752726(40719590, +), ADediting_752727(40719619, +), ADediting_752728(40719664, +), ADediting_752729(40719673, +), ADediting_752730(40719679, +), ADediting_752731(40719726, +), ADediting_752732(40719743, +), ADediting_752733(40719765, +), ADediting_752734(40720133, +), ADediting_752735(40720201, +), ADediting_752736(40720209, +), ADediting_752737(40720212, +), ADediting_752738(40720213, +), ADediting_752739(40720214, +), ADediting_752740(40720215, +), ADediting_752741(40720218, +), ADediting_752742(40720247, +), ADediting_752743(40720256, +), ADediting_752744(40721010, +), ADediting_752745(40721027, +), ADediting_752746(40721471, +), ADediting_752747(40721496, +), ADediting_752748(40721549, +), ADediting_752749(40721552, +), ADediting_752750(40721569, +), ADediting_752751(40721603, +), ADediting_752752(40721621, +), ADediting_752753(40721630, +), ADediting_752754(40721631, +), ADediting_752755(40721643, +), ADediting_752756(40721645, +), ADediting_752757(40721646, +), ADediting_752758(40721722, +), ADediting_752759(40721742, +), ADediting_752760(40721744, +), ADediting_752761(40721814, +), ADediting_752762(40721818, +), ADediting_752763(40721841, +), ADediting_752764(40721848, +), ADediting_752765(40721849, +), ADediting_752766(40721902, +), ADediting_752767(40721904, +), ADediting_752768(40721907, +), ADediting_752769(40721921, +), ADediting_752770(40721933, +), ADediting_752771(40721950, +), ADediting_752772(40721951, +), ADediting_752773(40721956, +), ADediting_752774(40721958, +), ADediting_752775(40722808, +), ADediting_752776(40722856, +), ADediting_752777(40722889, +), ADediting_752778(40722894, +), ADediting_752779(40722916, +), ADediting_752780(40723026, +), ADediting_752781(40723168, +), ADediting_752782(40723598, +), ADediting_752783(40724130, +), ADediting_752784(40724150, +), ADediting_752785(40724205, +), ADediting_752786(40724261, +), ADediting_752787(40724279, +), ADediting_752788(40724283, +), ADediting_752789(40724310, +), ADediting_752790(40724315, +), ADediting_752791(40724331, +), ADediting_752792(40724692, +), ADediting_752793(40724693, +), ADediting_752794(40724700, +), ADediting_752795(40724773, +), ADediting_752796(40724802, +), ADediting_752797(40724806, +), ADediting_752798(40724818, +), ADediting_752799(40724838, +), ADediting_752800(40724854, +), ADediting_752801(40724869, +), ADediting_752802(40724923, +), ADediting_752803(40728340, +), ADediting_752804(40729566, +), ADediting_752805(40729567, +), ADediting_752806(40729589, +), ADediting_752807(40729601, +), ADediting_752808(40729604, +), ADediting_752809(40729606, +), ADediting_752810(40729647, +), ADediting_752811(40729660, +), ADediting_752812(40729688, +), ADediting_752813(40729712, +), ADediting_752814(40729719, +), ADediting_752815(40729723, +), ADediting_752816(40729937, +), ADediting_752817(40729964, +), ADediting_752818(40729966, +), ADediting_752819(40729972, +), ADediting_752820(40729977, +), ADediting_752821(40730027, +), ADediting_752822(40730041, +), ADediting_752823(40730070, +), ADediting_752824(40730076, +), ADediting_752825(40730079, +), ADediting_752826(40730117, +), ADediting_752827(40730146, +), ADediting_752828(40730159, +), ADediting_752829(40730197, +), ADediting_752830(40730200, +), ADediting_752831(40730211, +), ADediting_752832(40730287, +), ADediting_752833(40730291, +), ADediting_752834(40730293, +), ADediting_752835(40730481, +), ADediting_752836(40730482, +), ADediting_752837(40730490, +), ADediting_752838(40730501, +), ADediting_752839(40730549, +), ADediting_752840(40730561, +), ADediting_752841(40730664, +), ADediting_752842(40730665, +), ADediting_752843(40730726, +), ADediting_752844(40731690, +), ADediting_752845(40731702, +), ADediting_752846(40731983, +), ADediting_752847(40732005, +), ADediting_752848(40732034, +), ADediting_752849(40732039, +), ADediting_752850(40732108, +), ADediting_752851(40732117, +), ADediting_752852(40732126, +), ADediting_752853(40732130, +), ADediting_752854(40732152, +), ADediting_752855(40732172, +), ADediting_752856(40732190, +), ADediting_752857(40732376, +), ADediting_752858(40732409, +), ADediting_752859(40732706, +), ADediting_752860(40734657, +), ADediting_752861(40734709, +), ADediting_752862(40734882, +), ADediting_752863(40735171, +), ADediting_752864(40736014, +), ADediting_752865(40736033, +), ADediting_752866(40736036, +), ADediting_752867(40736037, +), ADediting_752868(40736045, +), ADediting_752869(40736080, +), ADediting_752870(40736129, +), ADediting_752871(40736134, +), ADediting_752872(40736138, +), ADediting_752873(40736144, +), ADediting_752874(40736148, +), ADediting_752875(40736170, +), ADediting_752876(40736183, +), ADediting_752877(40736215, +), ADediting_752878(40736247, +), ADediting_752879(40736555, +), ADediting_752880(40736578, +), ADediting_752881(40736604, +), ADediting_752882(40736633, +), ADediting_752883(40736643, +), ADediting_752884(40736702, +), ADediting_752885(40736734, +), ADediting_752886(40736740, +), ADediting_752887(40736770, +), ADediting_752888(40738098, +), ADediting_752889(40738477, +), ADediting_1556137(40729785, +), ADediting_1556138(40732189, +), ADediting_1556139(40734748, +), ADediting_1631463(40738079, +), |
Top |
RNA editing positional annotations for ITPKC using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_752725 | chr19_40719589_+ | intronic |
| ADediting_752726 | chr19_40719590_+ | intronic |
| ADediting_752727 | chr19_40719619_+ | intronic |
| ADediting_752728 | chr19_40719664_+ | intronic |
| ADediting_752729 | chr19_40719673_+ | intronic |
| ADediting_752730 | chr19_40719679_+ | intronic |
| ADediting_752731 | chr19_40719726_+ | intronic |
| ADediting_752732 | chr19_40719743_+ | intronic |
| ADediting_752733 | chr19_40719765_+ | intronic |
| ADediting_752734 | chr19_40720133_+ | intronic |
| ADediting_752735 | chr19_40720201_+ | intronic |
| ADediting_752736 | chr19_40720209_+ | intronic |
| ADediting_752737 | chr19_40720212_+ | intronic |
| ADediting_752738 | chr19_40720213_+ | intronic |
| ADediting_752739 | chr19_40720214_+ | intronic |
| ADediting_752740 | chr19_40720215_+ | intronic |
| ADediting_752741 | chr19_40720218_+ | intronic |
| ADediting_752742 | chr19_40720247_+ | intronic |
| ADediting_752743 | chr19_40720256_+ | intronic |
| ADediting_752744 | chr19_40721010_+ | intronic |
| ADediting_752745 | chr19_40721027_+ | intronic |
| ADediting_752746 | chr19_40721471_+ | intronic |
| ADediting_752747 | chr19_40721496_+ | intronic |
| ADediting_752748 | chr19_40721549_+ | intronic |
| ADediting_752749 | chr19_40721552_+ | intronic |
| ADediting_752750 | chr19_40721569_+ | intronic |
| ADediting_752751 | chr19_40721603_+ | intronic |
| ADediting_752752 | chr19_40721621_+ | intronic |
| ADediting_752753 | chr19_40721630_+ | intronic |
| ADediting_752754 | chr19_40721631_+ | intronic |
| ADediting_752755 | chr19_40721643_+ | intronic |
| ADediting_752756 | chr19_40721645_+ | intronic |
| ADediting_752757 | chr19_40721646_+ | intronic |
| ADediting_752758 | chr19_40721722_+ | intronic |
| ADediting_752759 | chr19_40721742_+ | intronic |
| ADediting_752760 | chr19_40721744_+ | intronic |
| ADediting_752761 | chr19_40721814_+ | intronic |
| ADediting_752762 | chr19_40721818_+ | intronic |
| ADediting_752763 | chr19_40721841_+ | intronic |
| ADediting_752764 | chr19_40721848_+ | intronic |
| ADediting_752765 | chr19_40721849_+ | intronic |
| ADediting_752766 | chr19_40721902_+ | intronic |
| ADediting_752767 | chr19_40721904_+ | intronic |
| ADediting_752768 | chr19_40721907_+ | intronic |
| ADediting_752769 | chr19_40721921_+ | intronic |
| ADediting_752770 | chr19_40721933_+ | intronic |
| ADediting_752771 | chr19_40721950_+ | intronic |
| ADediting_752772 | chr19_40721951_+ | intronic |
| ADediting_752773 | chr19_40721956_+ | intronic |
| ADediting_752774 | chr19_40721958_+ | intronic |
| ADediting_752775 | chr19_40722808_+ | intronic |
| ADediting_752776 | chr19_40722856_+ | intronic |
| ADediting_752777 | chr19_40722889_+ | intronic |
| ADediting_752778 | chr19_40722894_+ | intronic |
| ADediting_752779 | chr19_40722916_+ | intronic |
| ADediting_752780 | chr19_40723026_+ | intronic |
| ADediting_752781 | chr19_40723168_+ | intronic |
| ADediting_752782 | chr19_40723598_+ | intronic |
| ADediting_752783 | chr19_40724130_+ | intronic |
| ADediting_752784 | chr19_40724150_+ | intronic |
| ADediting_752785 | chr19_40724205_+ | intronic |
| ADediting_752786 | chr19_40724261_+ | intronic |
| ADediting_752787 | chr19_40724279_+ | intronic |
| ADediting_752788 | chr19_40724283_+ | intronic |
| ADediting_752789 | chr19_40724310_+ | intronic |
| ADediting_752790 | chr19_40724315_+ | intronic |
| ADediting_752791 | chr19_40724331_+ | intronic |
| ADediting_752792 | chr19_40724692_+ | intronic |
| ADediting_752793 | chr19_40724693_+ | intronic |
| ADediting_752794 | chr19_40724700_+ | intronic |
| ADediting_752795 | chr19_40724773_+ | intronic |
| ADediting_752796 | chr19_40724802_+ | intronic |
| ADediting_752797 | chr19_40724806_+ | intronic |
| ADediting_752798 | chr19_40724818_+ | intronic |
| ADediting_752799 | chr19_40724838_+ | intronic |
| ADediting_752800 | chr19_40724854_+ | intronic |
| ADediting_752801 | chr19_40724869_+ | intronic |
| ADediting_752802 | chr19_40724923_+ | intronic |
| ADediting_752803 | chr19_40728340_+ | intronic |
| ADediting_752804 | chr19_40729566_+ | intronic |
| ADediting_752805 | chr19_40729567_+ | intronic |
| ADediting_752806 | chr19_40729589_+ | intronic |
| ADediting_752807 | chr19_40729601_+ | intronic |
| ADediting_752808 | chr19_40729604_+ | intronic |
| ADediting_752809 | chr19_40729606_+ | intronic |
| ADediting_752810 | chr19_40729647_+ | intronic |
| ADediting_752811 | chr19_40729660_+ | intronic |
| ADediting_752812 | chr19_40729688_+ | intronic |
| ADediting_752813 | chr19_40729712_+ | intronic |
| ADediting_752814 | chr19_40729719_+ | intronic |
| ADediting_752815 | chr19_40729723_+ | intronic |
| ADediting_752816 | chr19_40729937_+ | intronic |
| ADediting_752817 | chr19_40729964_+ | intronic |
| ADediting_752818 | chr19_40729966_+ | intronic |
| ADediting_752819 | chr19_40729972_+ | intronic |
| ADediting_752820 | chr19_40729977_+ | intronic |
| ADediting_752821 | chr19_40730027_+ | intronic |
| ADediting_752822 | chr19_40730041_+ | intronic |
| ADediting_752823 | chr19_40730070_+ | intronic |
| ADediting_752824 | chr19_40730076_+ | intronic |
| ADediting_752825 | chr19_40730079_+ | intronic |
| ADediting_752826 | chr19_40730117_+ | intronic |
| ADediting_752827 | chr19_40730146_+ | intronic |
| ADediting_752828 | chr19_40730159_+ | intronic |
| ADediting_752829 | chr19_40730197_+ | intronic |
| ADediting_752830 | chr19_40730200_+ | intronic |
| ADediting_752831 | chr19_40730211_+ | intronic |
| ADediting_752832 | chr19_40730287_+ | intronic |
| ADediting_752833 | chr19_40730291_+ | intronic |
| ADediting_752834 | chr19_40730293_+ | intronic |
| ADediting_752835 | chr19_40730481_+ | intronic |
| ADediting_752836 | chr19_40730482_+ | intronic |
| ADediting_752837 | chr19_40730490_+ | intronic |
| ADediting_752838 | chr19_40730501_+ | intronic |
| ADediting_752839 | chr19_40730549_+ | intronic |
| ADediting_752840 | chr19_40730561_+ | intronic |
| ADediting_752841 | chr19_40730664_+ | intronic |
| ADediting_752842 | chr19_40730665_+ | intronic |
| ADediting_752843 | chr19_40730726_+ | intronic |
| ADediting_752844 | chr19_40731690_+ | intronic |
| ADediting_752845 | chr19_40731702_+ | intronic |
| ADediting_752846 | chr19_40731983_+ | intronic |
| ADediting_752847 | chr19_40732005_+ | intronic |
| ADediting_752848 | chr19_40732034_+ | intronic |
| ADediting_752849 | chr19_40732039_+ | intronic |
| ADediting_752850 | chr19_40732108_+ | intronic |
| ADediting_752851 | chr19_40732117_+ | intronic |
| ADediting_752852 | chr19_40732126_+ | intronic |
| ADediting_752853 | chr19_40732130_+ | intronic |
| ADediting_752854 | chr19_40732152_+ | intronic |
| ADediting_752855 | chr19_40732172_+ | intronic |
| ADediting_752856 | chr19_40732190_+ | intronic |
| ADediting_752857 | chr19_40732376_+ | intronic |
| ADediting_752858 | chr19_40732409_+ | intronic |
| ADediting_752859 | chr19_40732706_+ | intronic |
| ADediting_752860 | chr19_40734657_+ | intronic |
| ADediting_752861 | chr19_40734709_+ | intronic |
| ADediting_752862 | chr19_40734882_+ | intronic |
| ADediting_752863 | chr19_40735171_+ | intronic |
| ADediting_752864 | chr19_40736014_+ | intronic |
| ADediting_752865 | chr19_40736033_+ | intronic |
| ADediting_752866 | chr19_40736036_+ | intronic |
| ADediting_752867 | chr19_40736037_+ | intronic |
| ADediting_752868 | chr19_40736045_+ | intronic |
| ADediting_752869 | chr19_40736080_+ | intronic |
| ADediting_752870 | chr19_40736129_+ | intronic |
| ADediting_752871 | chr19_40736134_+ | intronic |
| ADediting_752872 | chr19_40736138_+ | intronic |
| ADediting_752873 | chr19_40736144_+ | intronic |
| ADediting_752874 | chr19_40736148_+ | intronic |
| ADediting_752875 | chr19_40736170_+ | intronic |
| ADediting_752876 | chr19_40736183_+ | intronic |
| ADediting_752877 | chr19_40736215_+ | intronic |
| ADediting_752878 | chr19_40736247_+ | intronic |
| ADediting_752879 | chr19_40736555_+ | intronic |
| ADediting_752880 | chr19_40736578_+ | intronic |
| ADediting_752881 | chr19_40736604_+ | intronic |
| ADediting_752882 | chr19_40736633_+ | intronic |
| ADediting_752883 | chr19_40736643_+ | intronic |
| ADediting_752884 | chr19_40736702_+ | intronic |
| ADediting_752885 | chr19_40736734_+ | intronic |
| ADediting_752886 | chr19_40736740_+ | intronic |
| ADediting_752887 | chr19_40736770_+ | intronic |
| ADediting_752888 | chr19_40738098_+ | intronic |
| ADediting_752889 | chr19_40738477_+ | intronic |
| ADediting_1556137 | chr19_40729785_+ | intronic |
| ADediting_1556138 | chr19_40732189_+ | intronic |
| ADediting_1556139 | chr19_40734748_+ | intronic |
| ADediting_1631463 | chr19_40738079_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_752725 | chr19_40719589_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752726 | chr19_40719590_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752727 | chr19_40719619_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752728 | chr19_40719664_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752729 | chr19_40719673_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752730 | chr19_40719679_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752731 | chr19_40719726_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752732 | chr19_40719743_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752733 | chr19_40719765_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752734 | chr19_40720133_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752735 | chr19_40720201_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752736 | chr19_40720209_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752737 | chr19_40720212_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752738 | chr19_40720213_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752739 | chr19_40720214_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752740 | chr19_40720215_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752741 | chr19_40720218_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752742 | chr19_40720247_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752743 | chr19_40720256_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752744 | chr19_40721010_+ | SINE | Alu | Name=FLAM_C |
| ADediting_752745 | chr19_40721027_+ | SINE | Alu | Name=FLAM_C |
| ADediting_752746 | chr19_40721471_+ | SINE | Alu | Name=AluSx |
| ADediting_752747 | chr19_40721496_+ | SINE | Alu | Name=AluSx |
| ADediting_752748 | chr19_40721549_+ | SINE | Alu | Name=AluSx |
| ADediting_752749 | chr19_40721552_+ | SINE | Alu | Name=AluSx |
| ADediting_752750 | chr19_40721569_+ | SINE | Alu | Name=AluSx |
| ADediting_752751 | chr19_40721603_+ | SINE | Alu | Name=AluSx |
| ADediting_752752 | chr19_40721621_+ | SINE | Alu | Name=AluSx |
| ADediting_752753 | chr19_40721630_+ | SINE | Alu | Name=AluSx |
| ADediting_752754 | chr19_40721631_+ | SINE | Alu | Name=AluSx |
| ADediting_752755 | chr19_40721643_+ | SINE | Alu | Name=AluSx |
| ADediting_752756 | chr19_40721645_+ | SINE | Alu | Name=AluSx |
| ADediting_752757 | chr19_40721646_+ | SINE | Alu | Name=AluSx |
| ADediting_752758 | chr19_40721722_+ | SINE | Alu | Name=AluJb |
| ADediting_752759 | chr19_40721742_+ | SINE | Alu | Name=AluJb |
| ADediting_752760 | chr19_40721744_+ | SINE | Alu | Name=AluJb |
| ADediting_752761 | chr19_40721814_+ | SINE | Alu | Name=AluJb |
| ADediting_752762 | chr19_40721818_+ | SINE | Alu | Name=AluJb |
| ADediting_752763 | chr19_40721841_+ | SINE | Alu | Name=AluJb |
| ADediting_752764 | chr19_40721848_+ | SINE | Alu | Name=AluJb |
| ADediting_752765 | chr19_40721849_+ | SINE | Alu | Name=AluJb |
| ADediting_752766 | chr19_40721902_+ | SINE | Alu | Name=AluJb |
| ADediting_752767 | chr19_40721904_+ | SINE | Alu | Name=AluJb |
| ADediting_752768 | chr19_40721907_+ | SINE | Alu | Name=AluJb |
| ADediting_752769 | chr19_40721921_+ | SINE | Alu | Name=AluJb |
| ADediting_752770 | chr19_40721933_+ | SINE | Alu | Name=AluJb |
| ADediting_752771 | chr19_40721950_+ | SINE | Alu | Name=AluJb |
| ADediting_752772 | chr19_40721951_+ | SINE | Alu | Name=AluJb |
| ADediting_752773 | chr19_40721956_+ | SINE | Alu | Name=AluJb |
| ADediting_752774 | chr19_40721958_+ | SINE | Alu | Name=AluJb |
| ADediting_752775 | chr19_40722808_+ | SINE | Alu | Name=AluJb |
| ADediting_752776 | chr19_40722856_+ | SINE | Alu | Name=AluJb |
| ADediting_752777 | chr19_40722889_+ | SINE | Alu | Name=AluJb |
| ADediting_752778 | chr19_40722894_+ | SINE | Alu | Name=AluJb |
| ADediting_752779 | chr19_40722916_+ | SINE | Alu | Name=AluJb |
| ADediting_752780 | chr19_40723026_+ | SINE | Alu | Name=AluY |
| ADediting_752781 | chr19_40723168_+ | SINE | Alu | Name=AluY |
| ADediting_752782 | chr19_40723598_+ | SINE | Alu | Name=AluSx |
| ADediting_752783 | chr19_40724130_+ | SINE | Alu | Name=AluJr |
| ADediting_752784 | chr19_40724150_+ | SINE | Alu | Name=AluJr |
| ADediting_752785 | chr19_40724205_+ | SINE | Alu | Name=AluJr |
| ADediting_752786 | chr19_40724261_+ | SINE | Alu | Name=AluJr |
| ADediting_752787 | chr19_40724279_+ | SINE | Alu | Name=AluJr |
| ADediting_752788 | chr19_40724283_+ | SINE | Alu | Name=AluJr |
| ADediting_752789 | chr19_40724310_+ | SINE | Alu | Name=AluJr |
| ADediting_752790 | chr19_40724315_+ | SINE | Alu | Name=AluJr |
| ADediting_752791 | chr19_40724331_+ | SINE | Alu | Name=AluJr |
| ADediting_752792 | chr19_40724692_+ | SINE | Alu | Name=AluSz |
| ADediting_752793 | chr19_40724693_+ | SINE | Alu | Name=AluSz |
| ADediting_752794 | chr19_40724700_+ | SINE | Alu | Name=AluSz |
| ADediting_752795 | chr19_40724773_+ | SINE | Alu | Name=AluSz |
| ADediting_752796 | chr19_40724802_+ | SINE | Alu | Name=AluSz |
| ADediting_752797 | chr19_40724806_+ | SINE | Alu | Name=AluSz |
| ADediting_752798 | chr19_40724818_+ | SINE | Alu | Name=AluSz |
| ADediting_752799 | chr19_40724838_+ | SINE | Alu | Name=AluSz |
| ADediting_752800 | chr19_40724854_+ | SINE | Alu | Name=AluSz |
| ADediting_752801 | chr19_40724869_+ | SINE | Alu | Name=AluSz |
| ADediting_752802 | chr19_40724923_+ | SINE | Alu | Name=AluSz |
| ADediting_752803 | chr19_40728340_+ | SINE | Alu | Name=AluJr |
| ADediting_752804 | chr19_40729566_+ | SINE | Alu | Name=AluSp |
| ADediting_752805 | chr19_40729567_+ | SINE | Alu | Name=AluSp |
| ADediting_752806 | chr19_40729589_+ | SINE | Alu | Name=AluSp |
| ADediting_752807 | chr19_40729601_+ | SINE | Alu | Name=AluSp |
| ADediting_752808 | chr19_40729604_+ | SINE | Alu | Name=AluSp |
| ADediting_752809 | chr19_40729606_+ | SINE | Alu | Name=AluSp |
| ADediting_752810 | chr19_40729647_+ | SINE | Alu | Name=AluSp |
| ADediting_752811 | chr19_40729660_+ | SINE | Alu | Name=AluSp |
| ADediting_752812 | chr19_40729688_+ | SINE | Alu | Name=AluSp |
| ADediting_752813 | chr19_40729712_+ | SINE | Alu | Name=AluSp |
| ADediting_752814 | chr19_40729719_+ | SINE | Alu | Name=AluSp |
| ADediting_752815 | chr19_40729723_+ | SINE | Alu | Name=AluSp |
| ADediting_752816 | chr19_40729937_+ | LINE | L1 | Name=L1M5 |
| ADediting_752817 | chr19_40729964_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752818 | chr19_40729966_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752819 | chr19_40729972_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752820 | chr19_40729977_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752821 | chr19_40730027_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752822 | chr19_40730041_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752823 | chr19_40730070_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752824 | chr19_40730076_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752825 | chr19_40730079_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752826 | chr19_40730117_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752827 | chr19_40730146_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752828 | chr19_40730159_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752829 | chr19_40730197_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752830 | chr19_40730200_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752831 | chr19_40730211_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752832 | chr19_40730287_+ | SINE | Alu | Name=AluYk11 |
| ADediting_752833 | chr19_40730291_+ | SINE | Alu | Name=AluYk11 |
| ADediting_752834 | chr19_40730293_+ | SINE | Alu | Name=AluYk11 |
| ADediting_752835 | chr19_40730481_+ | SINE | Alu | Name=AluJo |
| ADediting_752836 | chr19_40730482_+ | SINE | Alu | Name=AluJo |
| ADediting_752837 | chr19_40730490_+ | SINE | Alu | Name=AluJo |
| ADediting_752838 | chr19_40730501_+ | SINE | Alu | Name=AluJo |
| ADediting_752839 | chr19_40730549_+ | SINE | Alu | Name=AluJo |
| ADediting_752840 | chr19_40730561_+ | SINE | Alu | Name=AluJo |
| ADediting_752841 | chr19_40730664_+ | SINE | Alu | Name=AluJo |
| ADediting_752842 | chr19_40730665_+ | SINE | Alu | Name=AluJo |
| ADediting_752844 | chr19_40731690_+ | LTR | ERVL | Name=MER21A |
| ADediting_752845 | chr19_40731702_+ | LTR | ERVL | Name=MER21A |
| ADediting_752846 | chr19_40731983_+ | SINE | Alu | Name=AluSz |
| ADediting_752847 | chr19_40732005_+ | SINE | Alu | Name=AluSz |
| ADediting_752848 | chr19_40732034_+ | SINE | Alu | Name=AluSz |
| ADediting_752849 | chr19_40732039_+ | SINE | Alu | Name=AluSz |
| ADediting_752850 | chr19_40732108_+ | SINE | Alu | Name=AluSz |
| ADediting_752851 | chr19_40732117_+ | SINE | Alu | Name=AluSz |
| ADediting_752852 | chr19_40732126_+ | SINE | Alu | Name=AluSz |
| ADediting_752853 | chr19_40732130_+ | SINE | Alu | Name=AluSz |
| ADediting_752854 | chr19_40732152_+ | SINE | Alu | Name=AluSz |
| ADediting_752855 | chr19_40732172_+ | SINE | Alu | Name=AluSz |
| ADediting_752856 | chr19_40732190_+ | SINE | Alu | Name=AluSz |
| ADediting_752857 | chr19_40732376_+ | SINE | Alu | Name=AluSx3 |
| ADediting_752858 | chr19_40732409_+ | SINE | Alu | Name=AluSx3 |
| ADediting_752859 | chr19_40732706_+ | SINE | Alu | Name=AluJo |
| ADediting_752860 | chr19_40734657_+ | SINE | Alu | Name=AluSz |
| ADediting_752861 | chr19_40734709_+ | SINE | Alu | Name=AluSz |
| ADediting_752862 | chr19_40734882_+ | SINE | Alu | Name=AluSx4 |
| ADediting_752863 | chr19_40735171_+ | SINE | Alu | Name=AluSz |
| ADediting_752864 | chr19_40736014_+ | SINE | Alu | Name=AluY |
| ADediting_752865 | chr19_40736033_+ | SINE | Alu | Name=AluY |
| ADediting_752866 | chr19_40736036_+ | SINE | Alu | Name=AluY |
| ADediting_752867 | chr19_40736037_+ | SINE | Alu | Name=AluY |
| ADediting_752868 | chr19_40736045_+ | SINE | Alu | Name=AluY |
| ADediting_752869 | chr19_40736080_+ | SINE | Alu | Name=AluY |
| ADediting_752870 | chr19_40736129_+ | SINE | Alu | Name=AluY |
| ADediting_752871 | chr19_40736134_+ | SINE | Alu | Name=AluY |
| ADediting_752872 | chr19_40736138_+ | SINE | Alu | Name=AluY |
| ADediting_752873 | chr19_40736144_+ | SINE | Alu | Name=AluY |
| ADediting_752874 | chr19_40736148_+ | SINE | Alu | Name=AluY |
| ADediting_752875 | chr19_40736170_+ | SINE | Alu | Name=AluY |
| ADediting_752876 | chr19_40736183_+ | SINE | Alu | Name=AluY |
| ADediting_752877 | chr19_40736215_+ | SINE | Alu | Name=AluY |
| ADediting_752878 | chr19_40736247_+ | SINE | Alu | Name=AluY |
| ADediting_752879 | chr19_40736555_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752880 | chr19_40736578_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752881 | chr19_40736604_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752882 | chr19_40736633_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752883 | chr19_40736643_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752884 | chr19_40736702_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752885 | chr19_40736734_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752886 | chr19_40736740_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752887 | chr19_40736770_+ | SINE | Alu | Name=AluSx1 |
| ADediting_752888 | chr19_40738098_+ | SINE | Alu | Name=AluSz |
| ADediting_752889 | chr19_40738477_+ | SINE | Alu | Name=AluSz |
| ADediting_1556137 | chr19_40729785_+ | SINE | Alu | Name=AluSp |
| ADediting_1556138 | chr19_40732189_+ | SINE | Alu | Name=AluSz |
| ADediting_1556139 | chr19_40734748_+ | SINE | Alu | Name=AluSz |
| ADediting_1631463 | chr19_40738079_+ | SINE | Alu | Name=AluSz |
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RNA A-to-I editing events in the alternative splicing sites for ITPKC |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ITPKC |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ITPKC |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for ITPKC |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000086544.3 | ENST00000263370.3 | ITPKC-201 | hsa-miR-151a-3p | chr19 | 40740068 | 40740074 | 7mer-m8 | 40740055 | 40740075 | 150 | -20.63 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000086544.3 | ENST00000263370.3 | ITPKC-201 | hsa-miR-4477b | chr19 | 40740668 | 40740674 | 7mer-m8 | 40740651 | 40740675 | 142 | -11.54 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000086544.3 | ENST00000263370.3 | ITPKC-201 | hsa-miR-4477b | chr19 | 40740668 | 40740674 | 7mer-m8 | 40740651 | 40740675 | 142 | -11.54 |
| ADediting_291761 | chr11_93733708_- | ENSG00000086544.3 | ENST00000263370.3 | ITPKC-201 | hsa-miR-1304-3p | chr19 | 40739796 | 40739802 | 7mer-m8 | 40739784 | 40739803 | 149 | -23.03 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ITPKC |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ITPKC |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_752732 | chr19_40719743_+ | 0.24501908243477 | 0.0662224510359931 | 0.396764431911826 | -0.0482968925307458 | 5.95417383517277e-08 | 0.30185412058298 |
| DLPFC | ADediting_752746 | chr19_40721471_+ | 0.906280599578074 | 0.00671373257450949 | 0.0280388778860352 | -0.124782621194439 | 7.84134676465844e-18 | 0.462447912705856 |
| DLPFC | ADediting_752757 | chr19_40721646_+ | 0.604119723701995 | 0.0295609680062228 | 0.176766503513061 | -0.0769160710035466 | 1.10459541882829e-14 | 0.420070253143943 |
| DLPFC | ADediting_752810 | chr19_40729647_+ | 0.345444719626198 | 0.0537634587134897 | 0.391463484299654 | -0.048840668418688 | 6.06702400180328e-08 | 0.301675923269335 |
| DLPFC | ADediting_752867 | chr19_40736037_+ | 0.0177602299304668 | 0.134570520961991 | 0.948408372930589 | 0.00368992725946727 | 2.03754430226614e-10 | 0.351000871585246 |
| DLPFC | ADediting_752868 | chr19_40736045_+ | 0.0078454342553185 | 0.150746325951373 | 0.294646733018748 | 0.0597094892068155 | 6.42195796626259e-08 | 0.301135591669895 |
| DLPFC | ADediting_752879 | chr19_40736555_+ | 0.0425614700801199 | 0.115263452498585 | 0.874097417838213 | 0.00903602082090255 | 2.44822319010193e-08 | 0.31015531612123 |
| DLPFC | ADediting_752882 | chr19_40736633_+ | 0.552914191760574 | 0.0338298112973908 | 0.248028944950218 | -0.0658028173388472 | 2.98244820421695e-13 | 0.398647268913503 |
| DLPFC | ADediting_752883 | chr19_40736643_+ | 0.425118808495686 | 0.0454592761134544 | 0.5660532415727 | -0.0327172811013062 | 1.05005221017208e-11 | 0.373618595838811 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.73912987765026e-08 | 0.313282279394216 | 1.28865194671447e-05 | 0.244951315303605 | 0.000273327914607286 | 0.205324074954939 |
| AC | 2.30120932745822e-23 | 0.574594602632389 | 4.38225708021560e-11 | 0.401191368073358 | 2.26090192582538e-14 | 0.458073523251795 |
| CER | 0.000296462861430174 | 0.291436963408513 | 2.67955103647045e-05 | 0.335663553298403 | 0.163480040086498 | 0.114358760465269 |
| IFG | 0.0266021219920873 | 0.442910300957647 | 0.0390659959658364 | 0.415117218821591 | 0.247155081827842 | 0.240349872983442 |
| STG | 0.000876924375914809 | 0.356380060918756 | 0.128766969266762 | 0.167070679244856 | 0.922407974856665 | -0.0107886657505228 |
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Relation with AD stages for ITPKC |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 8.54211576119353e-05 | 0.37219441238199 |
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RelatedDrugs for ITPKC |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ITPKC |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| ITPKC | C0010051 | Coronary Aneurysm | 1 | CTD_human |
| ITPKC | C0026691 | Mucocutaneous Lymph Node Syndrome | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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