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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for MYO15B |
 Gene summary |
| Gene information | Gene symbol | MYO15B | Gene ID | 80022 |
| Gene name | myosin XVB | |
| Synonyms | MYO15BP | |
| Cytomap | 17q25.1 | |
| Type of gene | protein-coding | |
| Description | myosin XVBmyosin XVB pseudogeneunconventional myosin XVBP pseudogene | |
| Modification date | 20200313 | |
| UniProtAcc | Q96JP2, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
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RNA A-to-I events for MYO15B |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_663562(75597691, +), ADediting_663563(75597769, +), ADediting_663564(75598193, +), ADediting_663565(75598213, +), ADediting_663566(75598354, +), ADediting_663567(75598362, +), ADediting_663568(75598390, +), ADediting_663569(75598391, +), ADediting_663570(75598431, +), ADediting_663571(75598444, +), ADediting_663572(75598457, +), ADediting_663573(75598467, +), ADediting_663574(75599355, +), ADediting_663575(75599400, +), ADediting_663576(75599401, +), ADediting_663577(75599404, +), ADediting_663578(75599414, +), ADediting_663579(75599416, +), ADediting_663580(75599472, +), ADediting_663581(75599528, +), ADediting_663582(75599532, +), ADediting_663583(75599546, +), ADediting_663584(75599547, +), ADediting_663585(75599559, +), ADediting_663586(75599567, +), ADediting_663587(75599643, +), ADediting_663588(75599651, +), ADediting_663589(75599652, +), ADediting_663590(75599657, +), ADediting_663591(75599674, +), ADediting_663592(75599682, +), ADediting_663593(75599695, +), ADediting_663594(75599733, +), ADediting_663595(75599738, +), ADediting_663596(75599743, +), ADediting_663597(75599774, +), ADediting_663598(75599780, +), ADediting_663599(75599797, +), ADediting_663600(75600156, +), ADediting_663601(75600209, +), ADediting_663602(75600679, +), ADediting_663603(75601045, +), ADediting_663604(75601069, +), ADediting_663605(75601165, +), ADediting_663606(75601177, +), ADediting_663607(75603627, +), ADediting_663608(75604956, +), ADediting_663609(75604973, +), ADediting_663610(75604976, +), ADediting_663611(75605044, +), ADediting_663612(75606354, +), ADediting_663613(75606432, +), ADediting_663614(75607735, +), ADediting_663615(75608188, +), ADediting_663616(75608219, +), ADediting_663617(75608319, +), ADediting_663618(75608514, +), ADediting_663619(75608520, +), ADediting_663620(75608521, +), ADediting_663621(75608526, +), ADediting_663622(75608534, +), ADediting_663623(75608543, +), ADediting_663624(75608547, +), ADediting_663625(75608582, +), ADediting_663626(75608614, +), ADediting_663627(75608617, +), ADediting_663628(75608628, +), ADediting_663629(75608645, +), ADediting_663630(75608658, +), ADediting_663631(75608659, +), ADediting_663632(75608675, +), ADediting_663633(75609140, +), ADediting_663634(75609305, +), ADediting_1549125(75597760, +), ADediting_1549126(75597793, +), ADediting_1549127(75597795, +), ADediting_1549128(75597799, +), ADediting_1549129(75600517, +), ADediting_1549130(75601261, +), ADediting_1549131(75608223, +), ADediting_1549132(75609284, +), |
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RNA editing positional annotations for MYO15B using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_663602 | chr17_75600679_+ | nonsynonymous SNV | ENST00000610510.4 | c.A3365G | p.Q1122R | . | . | . |
| ADediting_663602 | chr17_75600679_+ | nonsynonymous SNV | ENST00000633867.1 | c.A347G | p.Q116R | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_663562 | chr17_75597691_+ | intronic |
| ADediting_663563 | chr17_75597769_+ | intronic |
| ADediting_663564 | chr17_75598193_+ | intronic |
| ADediting_663565 | chr17_75598213_+ | intronic |
| ADediting_663566 | chr17_75598354_+ | intronic |
| ADediting_663567 | chr17_75598362_+ | intronic |
| ADediting_663568 | chr17_75598390_+ | intronic |
| ADediting_663569 | chr17_75598391_+ | intronic |
| ADediting_663570 | chr17_75598431_+ | intronic |
| ADediting_663571 | chr17_75598444_+ | intronic |
| ADediting_663572 | chr17_75598457_+ | intronic |
| ADediting_663573 | chr17_75598467_+ | intronic |
| ADediting_663574 | chr17_75599355_+ | intronic |
| ADediting_663575 | chr17_75599400_+ | intronic |
| ADediting_663576 | chr17_75599401_+ | intronic |
| ADediting_663577 | chr17_75599404_+ | intronic |
| ADediting_663578 | chr17_75599414_+ | intronic |
| ADediting_663579 | chr17_75599416_+ | intronic |
| ADediting_663580 | chr17_75599472_+ | intronic |
| ADediting_663581 | chr17_75599528_+ | intronic |
| ADediting_663582 | chr17_75599532_+ | intronic |
| ADediting_663583 | chr17_75599546_+ | intronic |
| ADediting_663584 | chr17_75599547_+ | intronic |
| ADediting_663585 | chr17_75599559_+ | intronic |
| ADediting_663586 | chr17_75599567_+ | intronic |
| ADediting_663587 | chr17_75599643_+ | intronic |
| ADediting_663588 | chr17_75599651_+ | intronic |
| ADediting_663589 | chr17_75599652_+ | intronic |
| ADediting_663590 | chr17_75599657_+ | intronic |
| ADediting_663591 | chr17_75599674_+ | intronic |
| ADediting_663592 | chr17_75599682_+ | intronic |
| ADediting_663593 | chr17_75599695_+ | intronic |
| ADediting_663594 | chr17_75599733_+ | intronic |
| ADediting_663595 | chr17_75599738_+ | intronic |
| ADediting_663596 | chr17_75599743_+ | intronic |
| ADediting_663597 | chr17_75599774_+ | intronic |
| ADediting_663598 | chr17_75599780_+ | intronic |
| ADediting_663599 | chr17_75599797_+ | intronic |
| ADediting_663600 | chr17_75600156_+ | intronic |
| ADediting_663601 | chr17_75600209_+ | intronic |
| ADediting_663602 | chr17_75600679_+ | exonic |
| ADediting_663603 | chr17_75601045_+ | intronic |
| ADediting_663604 | chr17_75601069_+ | intronic |
| ADediting_663605 | chr17_75601165_+ | intronic |
| ADediting_663606 | chr17_75601177_+ | intronic |
| ADediting_663607 | chr17_75603627_+ | intronic |
| ADediting_663608 | chr17_75604956_+ | intronic |
| ADediting_663609 | chr17_75604973_+ | intronic |
| ADediting_663610 | chr17_75604976_+ | intronic |
| ADediting_663611 | chr17_75605044_+ | intronic |
| ADediting_663612 | chr17_75606354_+ | intronic |
| ADediting_663613 | chr17_75606432_+ | intronic |
| ADediting_663614 | chr17_75607735_+ | intronic |
| ADediting_663615 | chr17_75608188_+ | intronic |
| ADediting_663616 | chr17_75608219_+ | intronic |
| ADediting_663617 | chr17_75608319_+ | intronic |
| ADediting_663618 | chr17_75608514_+ | intronic |
| ADediting_663619 | chr17_75608520_+ | intronic |
| ADediting_663620 | chr17_75608521_+ | intronic |
| ADediting_663621 | chr17_75608526_+ | intronic |
| ADediting_663622 | chr17_75608534_+ | intronic |
| ADediting_663623 | chr17_75608543_+ | intronic |
| ADediting_663624 | chr17_75608547_+ | intronic |
| ADediting_663625 | chr17_75608582_+ | intronic |
| ADediting_663626 | chr17_75608614_+ | intronic |
| ADediting_663627 | chr17_75608617_+ | intronic |
| ADediting_663628 | chr17_75608628_+ | intronic |
| ADediting_663629 | chr17_75608645_+ | intronic |
| ADediting_663630 | chr17_75608658_+ | intronic |
| ADediting_663631 | chr17_75608659_+ | intronic |
| ADediting_663632 | chr17_75608675_+ | intronic |
| ADediting_663633 | chr17_75609140_+ | intronic |
| ADediting_663634 | chr17_75609305_+ | intronic |
| ADediting_1549125 | chr17_75597760_+ | intronic |
| ADediting_1549126 | chr17_75597793_+ | intronic |
| ADediting_1549127 | chr17_75597795_+ | intronic |
| ADediting_1549128 | chr17_75597799_+ | intronic |
| ADediting_1549129 | chr17_75600517_+ | intronic |
| ADediting_1549130 | chr17_75601261_+ | intronic |
| ADediting_1549131 | chr17_75608223_+ | intronic |
| ADediting_1549132 | chr17_75609284_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_663562 | chr17_75597691_+ | SINE | Alu | Name=AluJb |
| ADediting_663563 | chr17_75597769_+ | SINE | Alu | Name=AluJb |
| ADediting_663564 | chr17_75598193_+ | SINE | Alu | Name=AluSc |
| ADediting_663565 | chr17_75598213_+ | SINE | Alu | Name=AluSc |
| ADediting_663566 | chr17_75598354_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663567 | chr17_75598362_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663568 | chr17_75598390_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663569 | chr17_75598391_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663570 | chr17_75598431_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663571 | chr17_75598444_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663572 | chr17_75598457_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663573 | chr17_75598467_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_663574 | chr17_75599355_+ | SINE | Alu | Name=AluY |
| ADediting_663575 | chr17_75599400_+ | SINE | Alu | Name=AluY |
| ADediting_663576 | chr17_75599401_+ | SINE | Alu | Name=AluY |
| ADediting_663577 | chr17_75599404_+ | SINE | Alu | Name=AluY |
| ADediting_663578 | chr17_75599414_+ | SINE | Alu | Name=AluY |
| ADediting_663579 | chr17_75599416_+ | SINE | Alu | Name=AluY |
| ADediting_663580 | chr17_75599472_+ | SINE | Alu | Name=AluY |
| ADediting_663581 | chr17_75599528_+ | SINE | Alu | Name=AluY |
| ADediting_663582 | chr17_75599532_+ | SINE | Alu | Name=AluY |
| ADediting_663583 | chr17_75599546_+ | SINE | Alu | Name=AluY |
| ADediting_663584 | chr17_75599547_+ | SINE | Alu | Name=AluY |
| ADediting_663585 | chr17_75599559_+ | SINE | Alu | Name=AluY |
| ADediting_663586 | chr17_75599567_+ | SINE | Alu | Name=AluY |
| ADediting_663587 | chr17_75599643_+ | SINE | Alu | Name=AluYc |
| ADediting_663588 | chr17_75599651_+ | SINE | Alu | Name=AluYc |
| ADediting_663589 | chr17_75599652_+ | SINE | Alu | Name=AluYc |
| ADediting_663590 | chr17_75599657_+ | SINE | Alu | Name=AluYc |
| ADediting_663591 | chr17_75599674_+ | SINE | Alu | Name=AluYc |
| ADediting_663592 | chr17_75599682_+ | SINE | Alu | Name=AluYc |
| ADediting_663593 | chr17_75599695_+ | SINE | Alu | Name=AluYc |
| ADediting_663594 | chr17_75599733_+ | SINE | Alu | Name=AluYc |
| ADediting_663595 | chr17_75599738_+ | SINE | Alu | Name=AluYc |
| ADediting_663596 | chr17_75599743_+ | SINE | Alu | Name=AluYc |
| ADediting_663597 | chr17_75599774_+ | SINE | Alu | Name=AluYc |
| ADediting_663598 | chr17_75599780_+ | SINE | Alu | Name=AluYc |
| ADediting_663599 | chr17_75599797_+ | SINE | Alu | Name=AluYc |
| ADediting_663600 | chr17_75600156_+ | SINE | Alu | Name=AluY |
| ADediting_663601 | chr17_75600209_+ | SINE | Alu | Name=AluY |
| ADediting_663602 | chr17_75600679_+ | SINE | Alu | Name=AluSq2 |
| ADediting_663603 | chr17_75601045_+ | SINE | Alu | Name=AluSx3 |
| ADediting_663604 | chr17_75601069_+ | SINE | Alu | Name=AluSx3 |
| ADediting_663605 | chr17_75601165_+ | SINE | Alu | Name=AluSx3 |
| ADediting_663606 | chr17_75601177_+ | SINE | Alu | Name=AluSx3 |
| ADediting_663608 | chr17_75604956_+ | SINE | Alu | Name=AluSp |
| ADediting_663609 | chr17_75604973_+ | SINE | Alu | Name=AluSp |
| ADediting_663610 | chr17_75604976_+ | SINE | Alu | Name=AluSp |
| ADediting_663611 | chr17_75605044_+ | SINE | Alu | Name=AluSp |
| ADediting_663612 | chr17_75606354_+ | SINE | Alu | Name=AluSq |
| ADediting_663613 | chr17_75606432_+ | SINE | Alu | Name=AluSq |
| ADediting_663614 | chr17_75607735_+ | SINE | Alu | Name=AluSx1 |
| ADediting_663615 | chr17_75608188_+ | SINE | Alu | Name=AluSx1 |
| ADediting_663616 | chr17_75608219_+ | SINE | Alu | Name=AluSx1 |
| ADediting_663617 | chr17_75608319_+ | SINE | Alu | Name=AluSx1 |
| ADediting_663618 | chr17_75608514_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663619 | chr17_75608520_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663620 | chr17_75608521_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663621 | chr17_75608526_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663622 | chr17_75608534_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663623 | chr17_75608543_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663624 | chr17_75608547_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663625 | chr17_75608582_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663626 | chr17_75608614_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663627 | chr17_75608617_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663628 | chr17_75608628_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663629 | chr17_75608645_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663630 | chr17_75608658_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663631 | chr17_75608659_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663632 | chr17_75608675_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663633 | chr17_75609140_+ | SINE | Alu | Name=AluSz6 |
| ADediting_663634 | chr17_75609305_+ | SINE | Alu | Name=AluJr4 |
| ADediting_1549125 | chr17_75597760_+ | SINE | Alu | Name=AluJb |
| ADediting_1549126 | chr17_75597793_+ | SINE | Alu | Name=AluJb |
| ADediting_1549127 | chr17_75597795_+ | SINE | Alu | Name=AluJb |
| ADediting_1549128 | chr17_75597799_+ | SINE | Alu | Name=AluJb |
| ADediting_1549129 | chr17_75600517_+ | SINE | Alu | Name=AluJr |
| ADediting_1549130 | chr17_75601261_+ | SINE | Alu | Name=AluJr |
| ADediting_1549131 | chr17_75608223_+ | SINE | Alu | Name=AluSx1 |
| ADediting_1549132 | chr17_75609284_+ | SINE | Alu | Name=AluJr4 |
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RNA A-to-I editing events in the alternative splicing sites for MYO15B |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| ES | ADediting_663602 | chr17_75600679_+ | 75600678:75600686 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| ES | ADediting_663602 | chr17_75600679_+ | 75600678:75600686 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| ES | ADediting_663602 | chr17_75600679_+ | 75600678:75600686 | 5ss | 2e | CAGGTTCAA | 1.19 | CGGGTTCAA | -6.26 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MYO15B |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for MYO15B |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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The effects of the RNA editing to the miRNA binding sites for MYO15B |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1391023 | chr8_140732605_- | ENSG00000266714.9 | ENST00000633867.1 | MYO15B-234 | hsa-miR-151a-3p | chr17 | 75622026 | 75622033 | 8mer-1a | 75622013 | 75622033 | 147 | -16.47 |
| ADediting_496066 | chr15_66496985_- | ENSG00000266714.9 | ENST00000633867.1 | MYO15B-234 | hsa-miR-4512 | chr17 | 75624050 | 75624057 | 8mer-1a | 75624033 | 75624057 | 146 | -19.14 |
| ADediting_496066 | chr15_66496985_- | ENSG00000266714.9 | ENST00000645453.2 | MYO15B-236 | hsa-miR-4512 | chr17 | 75626778 | 75626785 | 8mer-1a | 75626764 | 75626785 | 141 | -18.7 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1535951 | chr14_100874558_+ | ENSG00000266714.9 | ENST00000633867.1 | MYO15B-234 | hsa-miR-337-3p | chr17 | 75624420 | 75624426 | 7mer-m8 | 75624404 | 75624427 | 150 | -14.84 |
| ADediting_496066 | chr15_66496985_- | ENSG00000266714.9 | ENST00000633867.1 | MYO15B-234 | hsa-miR-4512 | chr17 | 75625906 | 75625912 | 7mer-m8 | 75625893 | 75625913 | 150 | -25.16 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for MYO15B |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000610510.4 | protein_coding |  |  |
| ENST00000633867.1 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_663602 | ENST00000610510.4 | chr17_75600679_+ | 3365 | -4400.50 | -4400.00 | -4400.50 |
| ADediting_663602 | ENST00000633867.1 | chr17_75600679_+ | 347 | -2849.60 | -2846.70 | -2849.60 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for MYO15B |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_663572 | chr17_75598457_+ | 0.0601646948169752 | 0.106879036628136 | 0.369079655038417 | -0.0511875896200302 | 3.41890196940281e-20 | 0.490749738593878 |
| DLPFC | ADediting_663608 | chr17_75604956_+ | 0.110793183734641 | 0.0907489945481733 | 0.928233088778277 | 0.00513624047837815 | 1.00321157134812e-08 | 0.318238294237734 |
| TCX | ADediting_663608 | chr17_75604956_+ | 0.556362985859607 | 0.0484073752024131 | 0.105542635392765 | -0.132679595232121 | 4.42733351781743e-05 | 0.326976865880573 |
| TCX | ADediting_663610 | chr17_75604976_+ | 0.242191087545956 | 0.0960741717227088 | 0.115741477379836 | -0.128968864388221 | 2.12865085683119e-08 | 0.437711673224364 |
| DLPFC | ADediting_663619 | chr17_75608520_+ | 0.00267030535030257 | 0.170021677730485 | 0.258085277781231 | 0.0644259243320445 | 4.98150094336447e-12 | 0.37903863044998 |
| DLPFC | ADediting_663620 | chr17_75608521_+ | 0.00665667414032746 | 0.153822340252969 | 0.712959139314803 | 0.0209768944155111 | 2.36003682158269e-15 | 0.429600404394738 |
| DLPFC | ADediting_663621 | chr17_75608526_+ | 0.170673245007505 | 0.0780097705062584 | 0.793630171103033 | 0.0149172929662008 | 7.39262075208244e-09 | 0.320950037947321 |
| DLPFC | ADediting_663622 | chr17_75608534_+ | 0.0655539764755752 | 0.104723281153519 | 0.612404404569262 | -0.0288861512374483 | 8.0504413245009e-17 | 0.449468913614418 |
| TCX | ADediting_663628 | chr17_75608628_+ | 0.155097710266416 | 0.116664873475783 | 0.495351950550126 | -0.0560958863048662 | 7.14549162612737e-05 | 0.318443818261272 |
| TCX | ADediting_663630 | chr17_75608658_+ | 0.964196471648969 | 0.00369600756256103 | 0.0295845129613163 | -0.177707948632755 | 9.81886418858811e-06 | 0.352288857173232 |
| TCX | ADediting_663631 | chr17_75608659_+ | 0.820602284756142 | -0.018670297011262 | 0.0105481173014696 | -0.208252171128631 | 3.34002355278364e-06 | 0.369159975041923 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 0.00182797812350553 | 0.176347911643053 | 0.00940137554466228 | 0.147295164575483 | 2.82179356569355e-48 | 0.70709251498806 |
| AC | 6.57574806153032e-07 | 0.308396357292349 | 0.000115104549864517 | 0.241486227197066 | 7.03359753941404e-13 | 0.433551381910835 |
| PCC | 0.294426178554838 | 0.0762540261160492 | 0.725321504777661 | 0.0255870042807671 | 4.8522454784669e-10 | 0.4309845307663 |
| TCX | 0.438986950463614 | 0.0636574814075863 | 0.000334350334303883 | -0.289028606492959 | 1.6816298348725e-15 | 0.591078479242109 |
| FP | 0.184651160995428 | 0.099885451893979 | 0.134671040230584 | -0.112561319794788 | 6.06209744742101e-17 | 0.573344243531628 |
| IFG | 0.0840397333455203 | 0.352399748219407 | 0.0908189794985389 | 0.345401709541902 | 1.25068747201977e-06 | 0.804540295990356 |
| PG | 0.00559510689978577 | -0.202408508899924 | 0.00527555006718505 | -0.203774340098294 | 6.56195151419024e-17 | 0.562474462000527 |
| STG | 0.720670885426565 | 0.0395911738081305 | 0.164468391593364 | -0.153081256506786 | 1.71970941199899e-09 | 0.599257028857003 |
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Relation with AD stages for MYO15B |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| TCX | 0.00127192284571555 | 0.308941523963378 |
| PG | 1.83155491892602e-05 | 0.308535510924488 |
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RelatedDrugs for MYO15B |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MYO15B |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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