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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for SNX22

check button Gene summary
Gene informationGene symbol

SNX22

Gene ID

79856

Gene namesorting nexin 22
Synonyms-
Cytomap

15q22.31

Type of geneprotein-coding
Descriptionsorting nexin-22
Modification date20200320
UniProtAcc

Q96L94,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for SNX22

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_489636(64154216, +), ADediting_489637(64154760, +), ADediting_489638(64154774, +), ADediting_489639(64154782, +), ADediting_489640(64154783, +), ADediting_489641(64154788, +), ADediting_489642(64154791, +), ADediting_489643(64154799, +), ADediting_489644(64154804, +), ADediting_489645(64154805, +), ADediting_489646(64154818, +), ADediting_489647(64154823, +), ADediting_489648(64154824, +), ADediting_489649(64154828, +), ADediting_489650(64154831, +), ADediting_489651(64154839, +), ADediting_489652(64154842, +), ADediting_489653(64154848, +), ADediting_489654(64154854, +), ADediting_489655(64154861, +), ADediting_489656(64154862, +), ADediting_489657(64154873, +), ADediting_489658(64154876, +), ADediting_489659(64154877, +), ADediting_489660(64154878, +), ADediting_489661(64154879, +), ADediting_489662(64154880, +), ADediting_489663(64154882, +), ADediting_489664(64154885, +), ADediting_489665(64154887, +), ADediting_489666(64154890, +), ADediting_489667(64154919, +), ADediting_489668(64154920, +), ADediting_489669(64154925, +), ADediting_489670(64154929, +), ADediting_489671(64154937, +), ADediting_489672(64154982, +), ADediting_489673(64154984, +), ADediting_489674(64155007, +), ADediting_489675(64155015, +), ADediting_489676(64155020, +), ADediting_489677(64155025, +), ADediting_489678(64155044, +), ADediting_489679(64155064, +), ADediting_489680(64155081, +), ADediting_489681(64155093, +), ADediting_489682(64155103, +), ADediting_489683(64155105, +), ADediting_489684(64155109, +), ADediting_489685(64155129, +), ADediting_489686(64155130, +), ADediting_489687(64155138, +), ADediting_489688(64155144, +), ADediting_489689(64155145, +), ADediting_489690(64155147, +), ADediting_489691(64155160, +), ADediting_489692(64155172, +), ADediting_489693(64155185, +), ADediting_489694(64155197, +), ADediting_489695(64155202, +), ADediting_489696(64155206, +), ADediting_489697(64155223, +), ADediting_489698(64155224, +), ADediting_489699(64155225, +), ADediting_489700(64155237, +), ADediting_489701(64155265, +), ADediting_489702(64155269, +), ADediting_489703(64155284, +), ADediting_489704(64155288, +), ADediting_489705(64155298, +), ADediting_489706(64155315, +), ADediting_489707(64155343, +), ADediting_489708(64155345, +), ADediting_489709(64155346, +), ADediting_489710(64155393, +), ADediting_489711(64155403, +), ADediting_489712(64155419, +), ADediting_489713(64155420, +), ADediting_489714(64155426, +), ADediting_489715(64155433, +), ADediting_489716(64155441, +), ADediting_489717(64155442, +), ADediting_489718(64155446, +), ADediting_489719(64155490, +), ADediting_489720(64155492, +), ADediting_1539846(64155192, +), ADediting_1539847(64155297, +), ADediting_1622550(64154807, +),

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RNA editing positional annotations for SNX22 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_489636chr15_64154216_+intronic
ADediting_489637chr15_64154760_+UTR3
ADediting_489638chr15_64154774_+UTR3
ADediting_489639chr15_64154782_+UTR3
ADediting_489640chr15_64154783_+UTR3
ADediting_489641chr15_64154788_+UTR3
ADediting_489642chr15_64154791_+UTR3
ADediting_489643chr15_64154799_+UTR3
ADediting_489644chr15_64154804_+UTR3
ADediting_489645chr15_64154805_+UTR3
ADediting_489646chr15_64154818_+UTR3
ADediting_489647chr15_64154823_+UTR3
ADediting_489648chr15_64154824_+UTR3
ADediting_489649chr15_64154828_+UTR3
ADediting_489650chr15_64154831_+UTR3
ADediting_489651chr15_64154839_+UTR3
ADediting_489652chr15_64154842_+UTR3
ADediting_489653chr15_64154848_+UTR3
ADediting_489654chr15_64154854_+UTR3
ADediting_489655chr15_64154861_+UTR3
ADediting_489656chr15_64154862_+UTR3
ADediting_489657chr15_64154873_+UTR3
ADediting_489658chr15_64154876_+UTR3
ADediting_489659chr15_64154877_+UTR3
ADediting_489660chr15_64154878_+UTR3
ADediting_489661chr15_64154879_+UTR3
ADediting_489662chr15_64154880_+UTR3
ADediting_489663chr15_64154882_+UTR3
ADediting_489664chr15_64154885_+UTR3
ADediting_489665chr15_64154887_+UTR3
ADediting_489666chr15_64154890_+UTR3
ADediting_489667chr15_64154919_+UTR3
ADediting_489668chr15_64154920_+UTR3
ADediting_489669chr15_64154925_+UTR3
ADediting_489670chr15_64154929_+UTR3
ADediting_489671chr15_64154937_+UTR3
ADediting_489672chr15_64154982_+UTR3
ADediting_489673chr15_64154984_+UTR3
ADediting_489674chr15_64155007_+UTR3
ADediting_489675chr15_64155015_+UTR3
ADediting_489676chr15_64155020_+UTR3
ADediting_489677chr15_64155025_+UTR3
ADediting_489678chr15_64155044_+UTR3
ADediting_489679chr15_64155064_+UTR3
ADediting_489680chr15_64155081_+UTR3
ADediting_489681chr15_64155093_+UTR3
ADediting_489682chr15_64155103_+UTR3
ADediting_489683chr15_64155105_+UTR3
ADediting_489684chr15_64155109_+UTR3
ADediting_489685chr15_64155129_+UTR3
ADediting_489686chr15_64155130_+UTR3
ADediting_489687chr15_64155138_+UTR3
ADediting_489688chr15_64155144_+UTR3
ADediting_489689chr15_64155145_+UTR3
ADediting_489690chr15_64155147_+UTR3
ADediting_489691chr15_64155160_+UTR3
ADediting_489692chr15_64155172_+UTR3
ADediting_489693chr15_64155185_+UTR3
ADediting_489694chr15_64155197_+UTR3
ADediting_489695chr15_64155202_+UTR3
ADediting_489696chr15_64155206_+UTR3
ADediting_489697chr15_64155223_+UTR3
ADediting_489698chr15_64155224_+UTR3
ADediting_489699chr15_64155225_+UTR3
ADediting_489700chr15_64155237_+UTR3
ADediting_489701chr15_64155265_+UTR3
ADediting_489702chr15_64155269_+UTR3
ADediting_489703chr15_64155284_+UTR3
ADediting_489704chr15_64155288_+UTR3
ADediting_489705chr15_64155298_+UTR3
ADediting_489706chr15_64155315_+UTR3
ADediting_489707chr15_64155343_+UTR3
ADediting_489708chr15_64155345_+UTR3
ADediting_489709chr15_64155346_+UTR3
ADediting_489710chr15_64155393_+UTR3
ADediting_489711chr15_64155403_+UTR3
ADediting_489712chr15_64155419_+UTR3
ADediting_489713chr15_64155420_+UTR3
ADediting_489714chr15_64155426_+UTR3
ADediting_489715chr15_64155433_+UTR3
ADediting_489716chr15_64155441_+UTR3
ADediting_489717chr15_64155442_+UTR3
ADediting_489718chr15_64155446_+UTR3
ADediting_489719chr15_64155490_+UTR3
ADediting_489720chr15_64155492_+UTR3
ADediting_1539846chr15_64155192_+UTR3
ADediting_1539847chr15_64155297_+UTR3
ADediting_1622550chr15_64154807_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_489637chr15_64154760_+SINEAluName=AluSp
ADediting_489638chr15_64154774_+SINEAluName=AluSp
ADediting_489639chr15_64154782_+SINEAluName=AluSp
ADediting_489640chr15_64154783_+SINEAluName=AluSp
ADediting_489641chr15_64154788_+SINEAluName=AluSp
ADediting_489642chr15_64154791_+SINEAluName=AluSp
ADediting_489643chr15_64154799_+SINEAluName=AluSp
ADediting_489644chr15_64154804_+SINEAluName=AluSp
ADediting_489645chr15_64154805_+SINEAluName=AluSp
ADediting_489646chr15_64154818_+SINEAluName=AluSp
ADediting_489647chr15_64154823_+SINEAluName=AluSp
ADediting_489648chr15_64154824_+SINEAluName=AluSp
ADediting_489649chr15_64154828_+SINEAluName=AluSp
ADediting_489650chr15_64154831_+SINEAluName=AluSp
ADediting_489651chr15_64154839_+SINEAluName=AluSp
ADediting_489652chr15_64154842_+SINEAluName=AluSp
ADediting_489653chr15_64154848_+SINEAluName=AluSp
ADediting_489654chr15_64154854_+SINEAluName=AluSp
ADediting_489655chr15_64154861_+SINEAluName=AluSp
ADediting_489656chr15_64154862_+SINEAluName=AluSp
ADediting_489657chr15_64154873_+SINEAluName=AluSp
ADediting_489658chr15_64154876_+SINEAluName=AluSp
ADediting_489659chr15_64154877_+SINEAluName=AluSp
ADediting_489660chr15_64154878_+SINEAluName=AluSp
ADediting_489661chr15_64154879_+SINEAluName=AluSp
ADediting_489662chr15_64154880_+SINEAluName=AluSp
ADediting_489663chr15_64154882_+SINEAluName=AluSp
ADediting_489664chr15_64154885_+SINEAluName=AluSp
ADediting_489665chr15_64154887_+SINEAluName=AluSp
ADediting_489666chr15_64154890_+SINEAluName=AluSp
ADediting_489667chr15_64154919_+SINEAluName=AluSp
ADediting_489668chr15_64154920_+SINEAluName=AluSp
ADediting_489669chr15_64154925_+SINEAluName=AluSp
ADediting_489670chr15_64154929_+SINEAluName=AluSp
ADediting_489671chr15_64154937_+SINEAluName=AluSp
ADediting_489672chr15_64154982_+SINEAluName=AluSq2
ADediting_489673chr15_64154984_+SINEAluName=AluSq2
ADediting_489674chr15_64155007_+SINEAluName=AluSq2
ADediting_489675chr15_64155015_+SINEAluName=AluSq2
ADediting_489676chr15_64155020_+SINEAluName=AluSq2
ADediting_489677chr15_64155025_+SINEAluName=AluSq2
ADediting_489678chr15_64155044_+SINEAluName=AluSq2
ADediting_489679chr15_64155064_+SINEAluName=AluSq2
ADediting_489680chr15_64155081_+SINEAluName=AluSq2
ADediting_489681chr15_64155093_+SINEAluName=AluSq2
ADediting_489682chr15_64155103_+SINEAluName=AluSq2
ADediting_489683chr15_64155105_+SINEAluName=AluSq2
ADediting_489684chr15_64155109_+SINEAluName=AluSq2
ADediting_489685chr15_64155129_+SINEAluName=AluSq2
ADediting_489686chr15_64155130_+SINEAluName=AluSq2
ADediting_489687chr15_64155138_+SINEAluName=AluSq2
ADediting_489688chr15_64155144_+SINEAluName=AluSq2
ADediting_489689chr15_64155145_+SINEAluName=AluSq2
ADediting_489690chr15_64155147_+SINEAluName=AluSq2
ADediting_489691chr15_64155160_+SINEAluName=AluSq2
ADediting_489692chr15_64155172_+SINEAluName=AluSq2
ADediting_489693chr15_64155185_+SINEAluName=AluSq2
ADediting_489694chr15_64155197_+SINEAluName=AluSq2
ADediting_489695chr15_64155202_+SINEAluName=AluSq2
ADediting_489696chr15_64155206_+SINEAluName=AluSq2
ADediting_489697chr15_64155223_+SINEAluName=AluSq2
ADediting_489698chr15_64155224_+SINEAluName=AluSq2
ADediting_489699chr15_64155225_+SINEAluName=AluSq2
ADediting_489700chr15_64155237_+SINEAluName=AluSq2
ADediting_489701chr15_64155265_+SINEAluName=AluSp
ADediting_489702chr15_64155269_+SINEAluName=AluSp
ADediting_489703chr15_64155284_+SINEAluName=AluSp
ADediting_489704chr15_64155288_+SINEAluName=AluSp
ADediting_489705chr15_64155298_+SINEAluName=AluSp
ADediting_489706chr15_64155315_+SINEAluName=AluSp
ADediting_489707chr15_64155343_+SINEAluName=AluSp
ADediting_489708chr15_64155345_+SINEAluName=AluSp
ADediting_489709chr15_64155346_+SINEAluName=AluSp
ADediting_489711chr15_64155403_+SINEAluName=FLAM_C
ADediting_489712chr15_64155419_+SINEAluName=FLAM_C
ADediting_489713chr15_64155420_+SINEAluName=FLAM_C
ADediting_489714chr15_64155426_+SINEAluName=FLAM_C
ADediting_489715chr15_64155433_+SINEAluName=FLAM_C
ADediting_489716chr15_64155441_+SINEAluName=FLAM_C
ADediting_489717chr15_64155442_+SINEAluName=FLAM_C
ADediting_489718chr15_64155446_+SINEAluName=FLAM_C
ADediting_489719chr15_64155490_+SINEAluName=FLAM_C
ADediting_489720chr15_64155492_+SINEAluName=FLAM_C
ADediting_1539846chr15_64155192_+SINEAluName=AluSq2
ADediting_1539847chr15_64155297_+SINEAluName=AluSp
ADediting_1622550chr15_64154807_+SINEAluName=AluSp

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RNA A-to-I editing events in the alternative splicing sites for SNX22

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SNX22

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot
boxplot
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs