|
||||||
|
 | |
| |
| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
| |
| |
| The effects of the RNA editing to the stability of the RNA structures |
| |
| |
| |
|
Gene summary for TEFM |
 Gene summary |
| Gene information | Gene symbol | TEFM | Gene ID | 79736 |
| Gene name | transcription elongation factor, mitochondrial | |
| Synonyms | C17orf42 | |
| Cytomap | 17q11.2 | |
| Type of gene | protein-coding | |
| Description | transcription elongation factor, mitochondrialtranscription elongation factor of mitochondria | |
| Modification date | 20200313 | |
| UniProtAcc | Q96QE5, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for TEFM |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_607609(30897627, -), ADediting_607610(30897704, -), ADediting_607611(30897787, -), ADediting_607612(30897788, -), ADediting_607613(30897791, -), ADediting_607614(30897836, -), ADediting_607615(30897838, -), ADediting_607616(30897866, -), ADediting_607617(30897998, -), ADediting_607618(30898010, -), ADediting_607619(30898020, -), ADediting_607620(30898033, -), ADediting_607621(30898034, -), ADediting_607622(30898037, -), ADediting_607623(30898038, -), ADediting_607624(30898052, -), ADediting_607625(30898063, -), ADediting_607626(30898075, -), ADediting_607627(30898083, -), ADediting_607628(30898089, -), ADediting_607629(30898111, -), ADediting_607630(30898116, -), ADediting_607631(30898121, -), ADediting_607632(30898127, -), ADediting_607633(30898129, -), ADediting_607634(30898135, -), ADediting_607635(30898139, -), ADediting_607636(30898141, -), ADediting_607637(30898142, -), ADediting_607638(30898164, -), ADediting_607639(30898165, -), ADediting_607640(30898168, -), ADediting_607641(30898169, -), ADediting_607642(30898195, -), ADediting_607643(30898201, -), ADediting_607644(30898208, -), ADediting_607645(30898214, -), ADediting_607646(30898216, -), ADediting_607647(30898225, -), ADediting_607648(30898233, -), ADediting_607649(30898241, -), ADediting_607650(30898383, -), ADediting_607651(30898385, -), ADediting_607652(30898394, -), ADediting_607653(30898408, -), ADediting_607654(30898423, -), ADediting_607655(30898428, -), ADediting_607656(30898459, -), ADediting_607657(30898470, -), ADediting_607658(30898474, -), ADediting_607659(30898478, -), ADediting_607660(30898484, -), ADediting_607661(30898492, -), ADediting_607662(30898510, -), ADediting_607663(30898552, -), ADediting_607664(30898582, -), ADediting_607665(30898588, -), ADediting_607666(30898623, -), ADediting_607667(30898624, -), ADediting_607668(30898865, -), ADediting_607669(30898896, -), ADediting_607670(30900740, -), ADediting_607671(30900835, -), ADediting_607672(30901055, -), ADediting_607673(30901129, -), ADediting_607674(30901132, -), ADediting_607675(30901141, -), ADediting_607676(30901149, -), ADediting_607677(30901165, -), ADediting_607678(30901185, -), ADediting_607679(30901194, -), ADediting_607680(30901200, -), ADediting_607681(30901214, -), ADediting_607682(30901240, -), ADediting_607683(30902917, -), ADediting_607684(30902946, -), ADediting_607685(30902949, -), ADediting_607686(30902960, -), ADediting_607687(30902963, -), ADediting_607688(30902970, -), ADediting_607689(30902977, -), ADediting_607690(30902980, -), ADediting_607691(30902986, -), ADediting_607692(30902995, -), ADediting_607693(30903019, -), ADediting_607694(30903021, -), ADediting_607695(30903025, -), ADediting_607696(30903031, -), ADediting_607697(30903043, -), ADediting_607698(30903060, -), ADediting_607699(30903061, -), ADediting_607700(30903067, -), ADediting_607701(30903074, -), ADediting_607702(30903080, -), ADediting_607703(30903083, -), ADediting_607704(30903084, -), ADediting_607705(30903094, -), ADediting_607706(30903102, -), ADediting_607707(30903112, -), ADediting_607708(30903257, -), ADediting_607709(30903312, -), ADediting_607710(30903323, -), ADediting_607711(30903332, -), ADediting_607712(30903333, -), ADediting_607713(30903335, -), ADediting_607714(30903338, -), ADediting_607715(30903355, -), ADediting_607716(30903359, -), ADediting_607717(30903365, -), ADediting_607718(30903383, -), ADediting_607719(30903391, -), ADediting_607720(30903395, -), ADediting_607721(30903396, -), ADediting_607722(30903397, -), ADediting_607723(30903400, -), ADediting_607724(30903406, -), ADediting_607725(30903409, -), ADediting_607726(30903420, -), ADediting_607727(30903421, -), ADediting_607728(30903440, -), ADediting_607729(30903451, -), ADediting_607730(30903453, -), ADediting_607731(30903459, -), ADediting_607732(30903460, -), ADediting_607733(30903474, -), ADediting_607734(30903476, -), ADediting_607735(30904807, -), ADediting_607736(30904827, -), ADediting_607737(30904907, -), ADediting_607738(30905408, -), ADediting_1545979(30897713, -), ADediting_1545980(30901188, -), ADediting_1545981(30901203, -), ADediting_1545982(30901239, -), ADediting_1545983(30901253, -), ADediting_1545984(30902886, -), |
Top |
RNA editing positional annotations for TEFM using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_607609 | chr17_30897627_- | intergenic |
| ADediting_607610 | chr17_30897704_- | intergenic |
| ADediting_607611 | chr17_30897787_- | intergenic |
| ADediting_607612 | chr17_30897788_- | intergenic |
| ADediting_607613 | chr17_30897791_- | intergenic |
| ADediting_607614 | chr17_30897836_- | intergenic |
| ADediting_607615 | chr17_30897838_- | intergenic |
| ADediting_607616 | chr17_30897866_- | intergenic |
| ADediting_607617 | chr17_30897998_- | downstream |
| ADediting_607618 | chr17_30898010_- | downstream |
| ADediting_607619 | chr17_30898020_- | downstream |
| ADediting_607620 | chr17_30898033_- | downstream |
| ADediting_607621 | chr17_30898034_- | downstream |
| ADediting_607622 | chr17_30898037_- | downstream |
| ADediting_607623 | chr17_30898038_- | downstream |
| ADediting_607624 | chr17_30898052_- | downstream |
| ADediting_607625 | chr17_30898063_- | downstream |
| ADediting_607626 | chr17_30898075_- | downstream |
| ADediting_607627 | chr17_30898083_- | downstream |
| ADediting_607628 | chr17_30898089_- | downstream |
| ADediting_607629 | chr17_30898111_- | upstream;downstream |
| ADediting_607630 | chr17_30898116_- | upstream;downstream |
| ADediting_607631 | chr17_30898121_- | upstream;downstream |
| ADediting_607632 | chr17_30898127_- | upstream;downstream |
| ADediting_607633 | chr17_30898129_- | upstream;downstream |
| ADediting_607634 | chr17_30898135_- | upstream;downstream |
| ADediting_607635 | chr17_30898139_- | upstream;downstream |
| ADediting_607636 | chr17_30898141_- | upstream;downstream |
| ADediting_607637 | chr17_30898142_- | upstream;downstream |
| ADediting_607638 | chr17_30898164_- | upstream;downstream |
| ADediting_607639 | chr17_30898165_- | upstream;downstream |
| ADediting_607640 | chr17_30898168_- | upstream;downstream |
| ADediting_607641 | chr17_30898169_- | upstream;downstream |
| ADediting_607642 | chr17_30898195_- | upstream;downstream |
| ADediting_607643 | chr17_30898201_- | upstream;downstream |
| ADediting_607644 | chr17_30898208_- | upstream;downstream |
| ADediting_607645 | chr17_30898214_- | upstream;downstream |
| ADediting_607646 | chr17_30898216_- | upstream;downstream |
| ADediting_607647 | chr17_30898225_- | upstream;downstream |
| ADediting_607648 | chr17_30898233_- | upstream;downstream |
| ADediting_607649 | chr17_30898241_- | upstream;downstream |
| ADediting_607650 | chr17_30898383_- | upstream;downstream |
| ADediting_607651 | chr17_30898385_- | upstream;downstream |
| ADediting_607652 | chr17_30898394_- | upstream;downstream |
| ADediting_607653 | chr17_30898408_- | upstream;downstream |
| ADediting_607654 | chr17_30898423_- | upstream;downstream |
| ADediting_607655 | chr17_30898428_- | upstream;downstream |
| ADediting_607656 | chr17_30898459_- | upstream;downstream |
| ADediting_607657 | chr17_30898470_- | upstream;downstream |
| ADediting_607658 | chr17_30898474_- | upstream;downstream |
| ADediting_607659 | chr17_30898478_- | upstream;downstream |
| ADediting_607660 | chr17_30898484_- | upstream;downstream |
| ADediting_607661 | chr17_30898492_- | upstream;downstream |
| ADediting_607662 | chr17_30898510_- | upstream;downstream |
| ADediting_607663 | chr17_30898552_- | upstream;downstream |
| ADediting_607664 | chr17_30898582_- | upstream;downstream |
| ADediting_607665 | chr17_30898588_- | upstream;downstream |
| ADediting_607666 | chr17_30898623_- | upstream;downstream |
| ADediting_607667 | chr17_30898624_- | upstream;downstream |
| ADediting_607668 | chr17_30898865_- | upstream;downstream |
| ADediting_607669 | chr17_30898896_- | upstream;downstream |
| ADediting_607670 | chr17_30900740_- | intronic |
| ADediting_607671 | chr17_30900835_- | intronic |
| ADediting_607672 | chr17_30901055_- | intronic |
| ADediting_607673 | chr17_30901129_- | intronic |
| ADediting_607674 | chr17_30901132_- | intronic |
| ADediting_607675 | chr17_30901141_- | intronic |
| ADediting_607676 | chr17_30901149_- | intronic |
| ADediting_607677 | chr17_30901165_- | intronic |
| ADediting_607678 | chr17_30901185_- | intronic |
| ADediting_607679 | chr17_30901194_- | intronic |
| ADediting_607680 | chr17_30901200_- | intronic |
| ADediting_607681 | chr17_30901214_- | intronic |
| ADediting_607682 | chr17_30901240_- | intronic |
| ADediting_607683 | chr17_30902917_- | intronic |
| ADediting_607684 | chr17_30902946_- | intronic |
| ADediting_607685 | chr17_30902949_- | intronic |
| ADediting_607686 | chr17_30902960_- | intronic |
| ADediting_607687 | chr17_30902963_- | intronic |
| ADediting_607688 | chr17_30902970_- | intronic |
| ADediting_607689 | chr17_30902977_- | intronic |
| ADediting_607690 | chr17_30902980_- | intronic |
| ADediting_607691 | chr17_30902986_- | intronic |
| ADediting_607692 | chr17_30902995_- | intronic |
| ADediting_607693 | chr17_30903019_- | intronic |
| ADediting_607694 | chr17_30903021_- | intronic |
| ADediting_607695 | chr17_30903025_- | intronic |
| ADediting_607696 | chr17_30903031_- | intronic |
| ADediting_607697 | chr17_30903043_- | intronic |
| ADediting_607698 | chr17_30903060_- | intronic |
| ADediting_607699 | chr17_30903061_- | intronic |
| ADediting_607700 | chr17_30903067_- | intronic |
| ADediting_607701 | chr17_30903074_- | intronic |
| ADediting_607702 | chr17_30903080_- | intronic |
| ADediting_607703 | chr17_30903083_- | intronic |
| ADediting_607704 | chr17_30903084_- | intronic |
| ADediting_607705 | chr17_30903094_- | intronic |
| ADediting_607706 | chr17_30903102_- | intronic |
| ADediting_607707 | chr17_30903112_- | intronic |
| ADediting_607708 | chr17_30903257_- | intronic |
| ADediting_607709 | chr17_30903312_- | intronic |
| ADediting_607710 | chr17_30903323_- | intronic |
| ADediting_607711 | chr17_30903332_- | intronic |
| ADediting_607712 | chr17_30903333_- | intronic |
| ADediting_607713 | chr17_30903335_- | intronic |
| ADediting_607714 | chr17_30903338_- | intronic |
| ADediting_607715 | chr17_30903355_- | intronic |
| ADediting_607716 | chr17_30903359_- | intronic |
| ADediting_607717 | chr17_30903365_- | intronic |
| ADediting_607718 | chr17_30903383_- | intronic |
| ADediting_607719 | chr17_30903391_- | intronic |
| ADediting_607720 | chr17_30903395_- | intronic |
| ADediting_607721 | chr17_30903396_- | intronic |
| ADediting_607722 | chr17_30903397_- | intronic |
| ADediting_607723 | chr17_30903400_- | intronic |
| ADediting_607724 | chr17_30903406_- | intronic |
| ADediting_607725 | chr17_30903409_- | intronic |
| ADediting_607726 | chr17_30903420_- | intronic |
| ADediting_607727 | chr17_30903421_- | intronic |
| ADediting_607728 | chr17_30903440_- | intronic |
| ADediting_607729 | chr17_30903451_- | intronic |
| ADediting_607730 | chr17_30903453_- | intronic |
| ADediting_607731 | chr17_30903459_- | intronic |
| ADediting_607732 | chr17_30903460_- | intronic |
| ADediting_607733 | chr17_30903474_- | intronic |
| ADediting_607734 | chr17_30903476_- | intronic |
| ADediting_607735 | chr17_30904807_- | intronic |
| ADediting_607736 | chr17_30904827_- | intronic |
| ADediting_607737 | chr17_30904907_- | intronic |
| ADediting_607738 | chr17_30905408_- | intronic |
| ADediting_1545979 | chr17_30897713_- | intergenic |
| ADediting_1545980 | chr17_30901188_- | intronic |
| ADediting_1545981 | chr17_30901203_- | intronic |
| ADediting_1545982 | chr17_30901239_- | intronic |
| ADediting_1545983 | chr17_30901253_- | intronic |
| ADediting_1545984 | chr17_30902886_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_607609 | chr17_30897627_- | SINE | Alu | Name=AluSx4 |
| ADediting_607610 | chr17_30897704_- | SINE | Alu | Name=AluSx4 |
| ADediting_607611 | chr17_30897787_- | SINE | Alu | Name=AluSx4 |
| ADediting_607612 | chr17_30897788_- | SINE | Alu | Name=AluSx4 |
| ADediting_607613 | chr17_30897791_- | SINE | Alu | Name=AluSx4 |
| ADediting_607614 | chr17_30897836_- | SINE | Alu | Name=AluSx4 |
| ADediting_607615 | chr17_30897838_- | SINE | Alu | Name=AluSx4 |
| ADediting_607616 | chr17_30897866_- | SINE | Alu | Name=AluSx4 |
| ADediting_607617 | chr17_30897998_- | SINE | Alu | Name=AluJb |
| ADediting_607618 | chr17_30898010_- | SINE | Alu | Name=AluJb |
| ADediting_607619 | chr17_30898020_- | SINE | Alu | Name=AluJb |
| ADediting_607620 | chr17_30898033_- | SINE | Alu | Name=AluJb |
| ADediting_607621 | chr17_30898034_- | SINE | Alu | Name=AluJb |
| ADediting_607622 | chr17_30898037_- | SINE | Alu | Name=AluJb |
| ADediting_607623 | chr17_30898038_- | SINE | Alu | Name=AluJb |
| ADediting_607624 | chr17_30898052_- | SINE | Alu | Name=AluJb |
| ADediting_607625 | chr17_30898063_- | SINE | Alu | Name=AluJb |
| ADediting_607626 | chr17_30898075_- | SINE | Alu | Name=AluJb |
| ADediting_607627 | chr17_30898083_- | SINE | Alu | Name=AluJb |
| ADediting_607628 | chr17_30898089_- | SINE | Alu | Name=AluJb |
| ADediting_607629 | chr17_30898111_- | SINE | Alu | Name=AluJb |
| ADediting_607630 | chr17_30898116_- | SINE | Alu | Name=AluJb |
| ADediting_607631 | chr17_30898121_- | SINE | Alu | Name=AluJb |
| ADediting_607632 | chr17_30898127_- | SINE | Alu | Name=AluJb |
| ADediting_607633 | chr17_30898129_- | SINE | Alu | Name=AluJb |
| ADediting_607634 | chr17_30898135_- | SINE | Alu | Name=AluJb |
| ADediting_607635 | chr17_30898139_- | SINE | Alu | Name=AluJb |
| ADediting_607636 | chr17_30898141_- | SINE | Alu | Name=AluJb |
| ADediting_607637 | chr17_30898142_- | SINE | Alu | Name=AluJb |
| ADediting_607638 | chr17_30898164_- | SINE | Alu | Name=AluJb |
| ADediting_607639 | chr17_30898165_- | SINE | Alu | Name=AluJb |
| ADediting_607640 | chr17_30898168_- | SINE | Alu | Name=AluJb |
| ADediting_607641 | chr17_30898169_- | SINE | Alu | Name=AluJb |
| ADediting_607642 | chr17_30898195_- | SINE | Alu | Name=AluJb |
| ADediting_607643 | chr17_30898201_- | SINE | Alu | Name=AluJb |
| ADediting_607644 | chr17_30898208_- | SINE | Alu | Name=AluJb |
| ADediting_607645 | chr17_30898214_- | SINE | Alu | Name=AluJb |
| ADediting_607646 | chr17_30898216_- | SINE | Alu | Name=AluJb |
| ADediting_607647 | chr17_30898225_- | SINE | Alu | Name=AluJb |
| ADediting_607648 | chr17_30898233_- | SINE | Alu | Name=AluJb |
| ADediting_607649 | chr17_30898241_- | SINE | Alu | Name=AluJb |
| ADediting_607650 | chr17_30898383_- | SINE | Alu | Name=AluSp |
| ADediting_607651 | chr17_30898385_- | SINE | Alu | Name=AluSp |
| ADediting_607652 | chr17_30898394_- | SINE | Alu | Name=AluSp |
| ADediting_607653 | chr17_30898408_- | SINE | Alu | Name=AluSp |
| ADediting_607654 | chr17_30898423_- | SINE | Alu | Name=AluSp |
| ADediting_607655 | chr17_30898428_- | SINE | Alu | Name=AluSp |
| ADediting_607656 | chr17_30898459_- | SINE | Alu | Name=AluSp |
| ADediting_607657 | chr17_30898470_- | SINE | Alu | Name=AluSp |
| ADediting_607658 | chr17_30898474_- | SINE | Alu | Name=AluSp |
| ADediting_607659 | chr17_30898478_- | SINE | Alu | Name=AluSp |
| ADediting_607660 | chr17_30898484_- | SINE | Alu | Name=AluSp |
| ADediting_607661 | chr17_30898492_- | SINE | Alu | Name=AluSp |
| ADediting_607662 | chr17_30898510_- | SINE | Alu | Name=AluSp |
| ADediting_607663 | chr17_30898552_- | SINE | Alu | Name=AluSp |
| ADediting_607664 | chr17_30898582_- | SINE | Alu | Name=AluSp |
| ADediting_607665 | chr17_30898588_- | SINE | Alu | Name=AluSp |
| ADediting_607666 | chr17_30898623_- | SINE | Alu | Name=AluSp |
| ADediting_607667 | chr17_30898624_- | SINE | Alu | Name=AluSp |
| ADediting_607668 | chr17_30898865_- | SINE | Alu | Name=AluJo |
| ADediting_607669 | chr17_30898896_- | SINE | Alu | Name=AluJo |
| ADediting_607670 | chr17_30900740_- | SINE | Alu | Name=AluY |
| ADediting_607671 | chr17_30900835_- | SINE | Alu | Name=AluY |
| ADediting_607672 | chr17_30901055_- | SINE | Alu | Name=AluSx1 |
| ADediting_607673 | chr17_30901129_- | SINE | Alu | Name=AluSx1 |
| ADediting_607674 | chr17_30901132_- | SINE | Alu | Name=AluSx1 |
| ADediting_607675 | chr17_30901141_- | SINE | Alu | Name=AluSx1 |
| ADediting_607676 | chr17_30901149_- | SINE | Alu | Name=AluSx1 |
| ADediting_607677 | chr17_30901165_- | SINE | Alu | Name=AluSx1 |
| ADediting_607678 | chr17_30901185_- | SINE | Alu | Name=AluSx1 |
| ADediting_607679 | chr17_30901194_- | SINE | Alu | Name=AluSx1 |
| ADediting_607680 | chr17_30901200_- | SINE | Alu | Name=AluSx1 |
| ADediting_607681 | chr17_30901214_- | SINE | Alu | Name=AluSx1 |
| ADediting_607682 | chr17_30901240_- | SINE | Alu | Name=AluSx1 |
| ADediting_607683 | chr17_30902917_- | SINE | Alu | Name=AluSc |
| ADediting_607684 | chr17_30902946_- | SINE | Alu | Name=AluSc |
| ADediting_607685 | chr17_30902949_- | SINE | Alu | Name=AluSc |
| ADediting_607686 | chr17_30902960_- | SINE | Alu | Name=AluSc |
| ADediting_607687 | chr17_30902963_- | SINE | Alu | Name=AluSc |
| ADediting_607688 | chr17_30902970_- | SINE | Alu | Name=AluSc |
| ADediting_607689 | chr17_30902977_- | SINE | Alu | Name=AluSc |
| ADediting_607690 | chr17_30902980_- | SINE | Alu | Name=AluSc |
| ADediting_607691 | chr17_30902986_- | SINE | Alu | Name=AluSc |
| ADediting_607692 | chr17_30902995_- | SINE | Alu | Name=AluSc |
| ADediting_607693 | chr17_30903019_- | SINE | Alu | Name=AluSc |
| ADediting_607694 | chr17_30903021_- | SINE | Alu | Name=AluSc |
| ADediting_607695 | chr17_30903025_- | SINE | Alu | Name=AluSc |
| ADediting_607696 | chr17_30903031_- | SINE | Alu | Name=AluSc |
| ADediting_607697 | chr17_30903043_- | SINE | Alu | Name=AluSc |
| ADediting_607698 | chr17_30903060_- | SINE | Alu | Name=AluSc |
| ADediting_607699 | chr17_30903061_- | SINE | Alu | Name=AluSc |
| ADediting_607700 | chr17_30903067_- | SINE | Alu | Name=AluSc |
| ADediting_607701 | chr17_30903074_- | SINE | Alu | Name=AluSc |
| ADediting_607702 | chr17_30903080_- | SINE | Alu | Name=AluSc |
| ADediting_607703 | chr17_30903083_- | SINE | Alu | Name=AluSc |
| ADediting_607704 | chr17_30903084_- | SINE | Alu | Name=AluSc |
| ADediting_607705 | chr17_30903094_- | SINE | Alu | Name=AluSc |
| ADediting_607706 | chr17_30903102_- | SINE | Alu | Name=AluSc |
| ADediting_607707 | chr17_30903112_- | SINE | Alu | Name=AluSc |
| ADediting_607708 | chr17_30903257_- | SINE | Alu | Name=AluSc |
| ADediting_607709 | chr17_30903312_- | SINE | Alu | Name=AluSc |
| ADediting_607710 | chr17_30903323_- | SINE | Alu | Name=AluSc |
| ADediting_607711 | chr17_30903332_- | SINE | Alu | Name=AluSc |
| ADediting_607712 | chr17_30903333_- | SINE | Alu | Name=AluSc |
| ADediting_607713 | chr17_30903335_- | SINE | Alu | Name=AluSc |
| ADediting_607714 | chr17_30903338_- | SINE | Alu | Name=AluSc |
| ADediting_607715 | chr17_30903355_- | SINE | Alu | Name=AluSc |
| ADediting_607716 | chr17_30903359_- | SINE | Alu | Name=AluSc |
| ADediting_607717 | chr17_30903365_- | SINE | Alu | Name=AluSc |
| ADediting_607718 | chr17_30903383_- | SINE | Alu | Name=AluSc |
| ADediting_607719 | chr17_30903391_- | SINE | Alu | Name=AluSc |
| ADediting_607720 | chr17_30903395_- | SINE | Alu | Name=AluSc |
| ADediting_607721 | chr17_30903396_- | SINE | Alu | Name=AluSc |
| ADediting_607722 | chr17_30903397_- | SINE | Alu | Name=AluSc |
| ADediting_607723 | chr17_30903400_- | SINE | Alu | Name=AluSc |
| ADediting_607724 | chr17_30903406_- | SINE | Alu | Name=AluSc |
| ADediting_607725 | chr17_30903409_- | SINE | Alu | Name=AluSc |
| ADediting_607726 | chr17_30903420_- | SINE | Alu | Name=AluSc |
| ADediting_607727 | chr17_30903421_- | SINE | Alu | Name=AluSc |
| ADediting_607728 | chr17_30903440_- | SINE | Alu | Name=AluSc |
| ADediting_607729 | chr17_30903451_- | SINE | Alu | Name=AluSc |
| ADediting_607730 | chr17_30903453_- | SINE | Alu | Name=AluSc |
| ADediting_607731 | chr17_30903459_- | SINE | Alu | Name=AluSc |
| ADediting_607732 | chr17_30903460_- | SINE | Alu | Name=AluSc |
| ADediting_607733 | chr17_30903474_- | SINE | Alu | Name=AluSc |
| ADediting_607734 | chr17_30903476_- | SINE | Alu | Name=AluSc |
| ADediting_607735 | chr17_30904807_- | SINE | Alu | Name=AluY |
| ADediting_607736 | chr17_30904827_- | SINE | Alu | Name=AluY |
| ADediting_607737 | chr17_30904907_- | SINE | Alu | Name=AluY |
| ADediting_607738 | chr17_30905408_- | SINE | Alu | Name=AluSp |
| ADediting_1545979 | chr17_30897713_- | SINE | Alu | Name=AluSx4 |
| ADediting_1545980 | chr17_30901188_- | SINE | Alu | Name=AluSx1 |
| ADediting_1545981 | chr17_30901203_- | SINE | Alu | Name=AluSx1 |
| ADediting_1545982 | chr17_30901239_- | SINE | Alu | Name=AluSx1 |
| ADediting_1545983 | chr17_30901253_- | SINE | Alu | Name=AluSx1 |
| ADediting_1545984 | chr17_30902886_- | SINE | Alu | Name=AluSc |
Top |
RNA A-to-I editing events in the alternative splicing sites for TEFM |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for TEFM |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
 | |
 | |
 | |
 | |
| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for TEFM |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for TEFM |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
 |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_607609 | chr17_30897627_- | ENSG00000172171.11 | ENST00000579183.1 | TEFM-203 | hsa-miR-3189-3p | chr17 | 30897626 | 30897632 | 7mer-m8 | 30897625 | 30897644 | 145 | -25.82 |
| ADediting_607609 | chr17_30897627_- | ENSG00000172171.11 | ENST00000579183.1 | TEFM-203 | hsa-miR-6813-3p | chr17 | 30897625 | 30897631 | 7mer-m8 | 30897624 | 30897644 | 140 | -12.15 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_286380 | chr11_79422188_- | ENSG00000172171.11 | ENST00000580840.1 | TEFM-204 | hsa-miR-5579-3p | chr17 | 30899013 | 30899020 | 8mer-1a | 30899013 | 30899036 | 153 | -16.77 |
| ADediting_286380 | chr11_79422188_- | ENSG00000172171.11 | ENST00000581216.6 | TEFM-205 | hsa-miR-5579-3p | chr17 | 30899013 | 30899020 | 8mer-1a | 30899013 | 30899036 | 153 | -16.77 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000172171.11 | ENST00000580840.1 | TEFM-204 | hsa-miR-4775 | chr17 | 30900187 | 30900194 | 8mer-1a | 30900187 | 30900210 | 158 | -12.63 |
| ADediting_98289 | chr1_32086992_+ | ENSG00000172171.11 | ENST00000580840.1 | TEFM-204 | hsa-miR-5585-3p | chr17 | 30899536 | 30899542 | 7mer-m8 | 30899535 | 30899556 | 144 | -16.68 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000172171.11 | ENST00000580840.1 | TEFM-204 | hsa-miR-589-3p | chr17 | 30899559 | 30899565 | 7mer-m8 | 30899558 | 30899581 | 142 | -11.18 |
| Differentially expressed gene-miRNA network |
Top |
The effects of the RNA editing to the stability of the RNA structures for TEFM |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000579183.1 | lncRNA |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_607609 | ENST00000579183.1 | chr17_30897627_- | 342 | -210.10 | -207.30 | -210.80 |
| ADediting_607610 | ENST00000579183.1 | chr17_30897704_- | 265 | -207.40 | -207.30 | -210.80 |
| ADediting_1545979 | ENST00000579183.1 | chr17_30897713_- | 256 | -209.10 | -207.30 | -210.80 |
Top |
Relation with ADAR for TEFM |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_607626 | chr17_30898075_- | 0.624330380163209 | 0.0279217340264376 | 0.352721121863829 | -0.0529589574623952 | 5.96366968996877e-10 | 0.342347713694487 |
| DLPFC | ADediting_607633 | chr17_30898129_- | 0.173898152353675 | 0.0774273700914118 | 0.90693723899057 | -0.00666647862408805 | 2.03049826692515e-10 | 0.351028360163998 |
| DLPFC | ADediting_607635 | chr17_30898139_- | 0.378599648368841 | 0.0501790713580975 | 0.56606851787057 | -0.0327159948767568 | 5.37321853377955e-08 | 0.302826387535828 |
| DLPFC | ADediting_607636 | chr17_30898141_- | 0.246590460216928 | 0.0660029246162522 | 0.746044625939918 | -0.0184670006389736 | 2.33502166861844e-09 | 0.330951144321958 |
| DLPFC | ADediting_607689 | chr17_30902977_- | 0.64976234390047 | 0.0258909828475627 | 0.421185663757337 | -0.045846095871259 | 7.9849475836199e-09 | 0.320267991965889 |
| DLPFC | ADediting_607692 | chr17_30902995_- | 0.814313880846463 | -0.0133929147274116 | 0.0284665251681905 | -0.124447527012843 | 5.03464519290419e-16 | 0.438848510472769 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 6.31382165121473e-32 | 0.601803184394771 | 2.5659295227453e-18 | 0.468482786125156 | 2.14781957658905e-07 | 0.289391444776827 |
| AC | 5.20086317136423e-54 | 0.787329760305063 | 2.93312922989109e-29 | 0.631790144027564 | 3.57011376339391e-23 | 0.572539421684591 |
| PCC | 1.431329402687e-19 | 0.593610367715968 | 1.10124253846097e-16 | 0.552898269432944 | 3.27127975028279e-10 | 0.4348167154528 |
| CER | 2.12858755728088e-31 | 0.775788347762603 | 8.41664124236739e-20 | 0.655813346643271 | 0.00314036857912954 | 0.239645163001549 |
| TCX | 1.19428536137544e-19 | 0.653768530532815 | 5.05383506411095e-05 | 0.324642971535179 | 8.45686801475249e-12 | 0.520721066156546 |
| FP | 2.61752911847394e-21 | 0.632865974326409 | 1.55801784157163e-20 | 0.623175849542243 | 1.78722118104843e-05 | 0.315515469983249 |
| IFG | 0.0782005449121111 | 0.358777686306047 | 0.00946587060978167 | 0.508366369397479 | 0.054726899152821 | 0.388839435505801 |
| PG | 2.0326066063252e-40 | 0.786818160916817 | 1.34472210190797e-23 | 0.64875022202882 | 0.354225702663965 | 0.0683098112596237 |
| STG | 4.81604001320438e-12 | 0.665851012988948 | 3.39571016075467e-10 | 0.619279160115273 | 0.209338359420881 | 0.138387369374166 |
Top |
Relation with AD stages for TEFM |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 9.52538521051237e-05 | 0.366610737408852 |
| TCX | 1.34133432173996e-05 | 0.409025252722914 |
Top |
RelatedDrugs for TEFM |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for TEFM |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|