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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for NEIL1 |
 Gene summary |
| Gene information | Gene symbol | NEIL1 | Gene ID | 79661 |
| Gene name | nei like DNA glycosylase 1 | |
| Synonyms | FPG1|NEI1|hFPG1 | |
| Cytomap | 15q24.2 | |
| Type of gene | protein-coding | |
| Description | endonuclease 8-like 1DNA endonuclease eight-like glycosylase 1DNA glycosylase/AP lyase Neil1DNA-(apurinic or apyrimidinic site) lyase Neil1NEH1endonuclease VIIIendonuclease VIII-like 1nei endonuclease VIII-like 1nei homolog 1nei-like protein 1 | |
| Modification date | 20200322 | |
| UniProtAcc | Q96FI4, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| NEIL1 | GO:0006284 | base-excision repair | 17611195 |
| NEIL1 | GO:0006979 | response to oxidative stress | 17611195 |
| NEIL1 | GO:0032074 | negative regulation of nuclease activity | 17611195 |
Top |
RNA A-to-I events for NEIL1 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_501743(75349552, +), ADediting_501744(75349560, +), ADediting_501745(75349561, +), ADediting_501746(75349566, +), ADediting_501747(75349578, +), ADediting_501748(75349604, +), ADediting_501749(75349618, +), ADediting_501750(75349627, +), ADediting_501751(75349638, +), ADediting_501752(75349649, +), ADediting_501753(75349655, +), ADediting_501754(75349658, +), ADediting_501755(75349667, +), ADediting_501756(75349693, +), ADediting_501757(75349694, +), ADediting_501758(75349703, +), ADediting_501759(75349720, +), ADediting_501760(75349723, +), ADediting_501761(75349724, +), ADediting_501762(75349742, +), ADediting_501763(75349755, +), ADediting_501764(75349759, +), ADediting_501765(75349768, +), ADediting_501766(75349771, +), ADediting_501767(75349784, +), ADediting_501768(75349794, +), ADediting_501769(75349798, +), ADediting_501770(75351295, +), ADediting_501771(75351324, +), ADediting_501772(75351329, +), ADediting_501773(75351340, +), ADediting_501774(75351343, +), ADediting_501775(75351345, +), ADediting_501776(75351350, +), ADediting_501777(75351355, +), ADediting_501778(75351362, +), ADediting_501779(75351368, +), ADediting_501780(75351375, +), ADediting_501781(75351388, +), ADediting_501782(75351394, +), ADediting_501783(75351406, +), ADediting_501784(75351415, +), ADediting_501785(75351450, +), ADediting_501786(75351451, +), ADediting_501787(75351461, +), ADediting_501788(75351523, +), ADediting_501789(75351534, +), ADediting_501790(75351545, +), ADediting_501791(75351686, +), ADediting_501792(75351748, +), ADediting_501793(75351749, +), ADediting_501794(75351752, +), ADediting_501795(75351762, +), ADediting_501796(75351768, +), ADediting_501797(75351788, +), ADediting_501798(75351789, +), ADediting_501799(75351796, +), ADediting_501800(75351802, +), ADediting_501801(75351805, +), ADediting_501802(75351811, +), ADediting_501803(75351819, +), ADediting_501804(75351831, +), ADediting_501805(75351884, +), ADediting_501806(75351896, +), ADediting_501807(75352884, +), ADediting_501808(75352885, +), ADediting_501809(75352890, +), ADediting_501810(75352907, +), ADediting_501811(75352925, +), ADediting_501812(75352930, +), ADediting_501813(75352933, +), ADediting_501814(75352941, +), ADediting_501815(75352953, +), ADediting_501816(75352954, +), ADediting_501817(75352956, +), ADediting_501818(75352963, +), ADediting_501819(75352964, +), ADediting_501820(75352969, +), ADediting_501821(75352975, +), ADediting_501822(75352994, +), ADediting_501823(75353014, +), ADediting_501824(75353020, +), ADediting_501825(75353021, +), ADediting_501826(75353026, +), ADediting_501827(75353030, +), ADediting_501828(75353047, +), ADediting_501829(75353051, +), ADediting_501830(75353052, +), ADediting_501831(75353060, +), ADediting_501832(75353061, +), ADediting_501833(75353062, +), ADediting_501834(75353092, +), ADediting_501835(75353107, +), ADediting_501836(75353112, +), ADediting_501837(75353132, +), ADediting_501838(75353274, +), ADediting_501839(75353280, +), ADediting_501840(75353305, +), ADediting_501841(75353311, +), ADediting_501842(75353322, +), ADediting_501843(75353323, +), ADediting_501844(75353335, +), ADediting_501845(75353337, +), ADediting_501846(75353347, +), ADediting_501847(75353348, +), ADediting_501848(75353351, +), ADediting_501849(75353355, +), ADediting_501850(75353361, +), ADediting_501851(75353363, +), ADediting_501852(75353371, +), ADediting_501853(75353374, +), ADediting_501854(75353409, +), ADediting_501855(75353411, +), ADediting_501856(75353415, +), ADediting_501857(75353426, +), ADediting_501858(75353435, +), ADediting_501859(75353443, +), ADediting_501860(75353447, +), ADediting_501861(75353448, +), ADediting_501862(75353461, +), ADediting_501863(75353477, +), ADediting_501864(75353478, +), ADediting_501865(75353486, +), ADediting_501866(75353487, +), ADediting_501867(75353488, +), ADediting_501868(75353500, +), ADediting_501869(75353502, +), ADediting_501870(75353517, +), ADediting_501871(75353745, +), ADediting_501872(75353746, +), ADediting_1540245(75349591, +), ADediting_1540246(75349596, +), ADediting_1540247(75349636, +), ADediting_1540248(75349637, +), ADediting_1540249(75349656, +), ADediting_1540250(75349734, +), ADediting_1540251(75351361, +), ADediting_1540252(75351531, +), ADediting_1540253(75351678, +), |
Top |
RNA editing positional annotations for NEIL1 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_501771 | chr15_75351324_+ | stoploss | ENST00000568519.5 | c.A458G | p.X153W | . | . | . |
| ADediting_501871 | chr15_75353745_+ | nonsynonymous SNV | ENST00000355059.9 | c.A725G | p.K242R | 0.089 | 0.014 | -1.49 |
| ADediting_501871 | chr15_75353745_+ | nonsynonymous SNV | ENST00000564784.5 | c.A725G | p.K242R | 0.089 | 0.014 | -1.49 |
| ADediting_501871 | chr15_75353745_+ | nonsynonymous SNV | ENST00000569035.5 | c.A725G | p.K242R | 0.089 | 0.014 | -1.49 |
| ADediting_501872 | chr15_75353746_+ | synonymous SNV | ENST00000355059.9 | c.A726G | p.K242K | . | . | . |
| ADediting_501872 | chr15_75353746_+ | synonymous SNV | ENST00000564784.5 | c.A726G | p.K242K | . | . | . |
| ADediting_501872 | chr15_75353746_+ | synonymous SNV | ENST00000569035.5 | c.A726G | p.K242K | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_501743 | chr15_75349552_+ | intronic |
| ADediting_501744 | chr15_75349560_+ | intronic |
| ADediting_501745 | chr15_75349561_+ | intronic |
| ADediting_501746 | chr15_75349566_+ | intronic |
| ADediting_501747 | chr15_75349578_+ | intronic |
| ADediting_501748 | chr15_75349604_+ | intronic |
| ADediting_501749 | chr15_75349618_+ | intronic |
| ADediting_501750 | chr15_75349627_+ | intronic |
| ADediting_501751 | chr15_75349638_+ | intronic |
| ADediting_501752 | chr15_75349649_+ | intronic |
| ADediting_501753 | chr15_75349655_+ | intronic |
| ADediting_501754 | chr15_75349658_+ | intronic |
| ADediting_501755 | chr15_75349667_+ | intronic |
| ADediting_501756 | chr15_75349693_+ | intronic |
| ADediting_501757 | chr15_75349694_+ | intronic |
| ADediting_501758 | chr15_75349703_+ | intronic |
| ADediting_501759 | chr15_75349720_+ | intronic |
| ADediting_501760 | chr15_75349723_+ | intronic |
| ADediting_501761 | chr15_75349724_+ | intronic |
| ADediting_501762 | chr15_75349742_+ | intronic |
| ADediting_501763 | chr15_75349755_+ | intronic |
| ADediting_501764 | chr15_75349759_+ | intronic |
| ADediting_501765 | chr15_75349768_+ | intronic |
| ADediting_501766 | chr15_75349771_+ | intronic |
| ADediting_501767 | chr15_75349784_+ | intronic |
| ADediting_501768 | chr15_75349794_+ | intronic |
| ADediting_501769 | chr15_75349798_+ | intronic |
| ADediting_501770 | chr15_75351295_+ | intronic |
| ADediting_501771 | chr15_75351324_+ | exonic |
| ADediting_501772 | chr15_75351329_+ | UTR3 |
| ADediting_501773 | chr15_75351340_+ | UTR3 |
| ADediting_501774 | chr15_75351343_+ | UTR3 |
| ADediting_501775 | chr15_75351345_+ | UTR3 |
| ADediting_501776 | chr15_75351350_+ | UTR3 |
| ADediting_501777 | chr15_75351355_+ | UTR3 |
| ADediting_501778 | chr15_75351362_+ | UTR3 |
| ADediting_501779 | chr15_75351368_+ | UTR3 |
| ADediting_501780 | chr15_75351375_+ | UTR3 |
| ADediting_501781 | chr15_75351388_+ | intronic |
| ADediting_501782 | chr15_75351394_+ | intronic |
| ADediting_501783 | chr15_75351406_+ | intronic |
| ADediting_501784 | chr15_75351415_+ | intronic |
| ADediting_501785 | chr15_75351450_+ | intronic |
| ADediting_501786 | chr15_75351451_+ | intronic |
| ADediting_501787 | chr15_75351461_+ | intronic |
| ADediting_501788 | chr15_75351523_+ | intronic |
| ADediting_501789 | chr15_75351534_+ | intronic |
| ADediting_501790 | chr15_75351545_+ | intronic |
| ADediting_501791 | chr15_75351686_+ | intronic |
| ADediting_501792 | chr15_75351748_+ | intronic |
| ADediting_501793 | chr15_75351749_+ | intronic |
| ADediting_501794 | chr15_75351752_+ | intronic |
| ADediting_501795 | chr15_75351762_+ | intronic |
| ADediting_501796 | chr15_75351768_+ | intronic |
| ADediting_501797 | chr15_75351788_+ | intronic |
| ADediting_501798 | chr15_75351789_+ | intronic |
| ADediting_501799 | chr15_75351796_+ | intronic |
| ADediting_501800 | chr15_75351802_+ | intronic |
| ADediting_501801 | chr15_75351805_+ | intronic |
| ADediting_501802 | chr15_75351811_+ | intronic |
| ADediting_501803 | chr15_75351819_+ | intronic |
| ADediting_501804 | chr15_75351831_+ | intronic |
| ADediting_501805 | chr15_75351884_+ | intronic |
| ADediting_501806 | chr15_75351896_+ | intronic |
| ADediting_501807 | chr15_75352884_+ | intronic |
| ADediting_501808 | chr15_75352885_+ | intronic |
| ADediting_501809 | chr15_75352890_+ | intronic |
| ADediting_501810 | chr15_75352907_+ | intronic |
| ADediting_501811 | chr15_75352925_+ | intronic |
| ADediting_501812 | chr15_75352930_+ | intronic |
| ADediting_501813 | chr15_75352933_+ | intronic |
| ADediting_501814 | chr15_75352941_+ | intronic |
| ADediting_501815 | chr15_75352953_+ | intronic |
| ADediting_501816 | chr15_75352954_+ | intronic |
| ADediting_501817 | chr15_75352956_+ | intronic |
| ADediting_501818 | chr15_75352963_+ | intronic |
| ADediting_501819 | chr15_75352964_+ | intronic |
| ADediting_501820 | chr15_75352969_+ | intronic |
| ADediting_501821 | chr15_75352975_+ | intronic |
| ADediting_501822 | chr15_75352994_+ | intronic |
| ADediting_501823 | chr15_75353014_+ | intronic |
| ADediting_501824 | chr15_75353020_+ | intronic |
| ADediting_501825 | chr15_75353021_+ | intronic |
| ADediting_501826 | chr15_75353026_+ | intronic |
| ADediting_501827 | chr15_75353030_+ | intronic |
| ADediting_501828 | chr15_75353047_+ | intronic |
| ADediting_501829 | chr15_75353051_+ | intronic |
| ADediting_501830 | chr15_75353052_+ | intronic |
| ADediting_501831 | chr15_75353060_+ | intronic |
| ADediting_501832 | chr15_75353061_+ | intronic |
| ADediting_501833 | chr15_75353062_+ | intronic |
| ADediting_501834 | chr15_75353092_+ | intronic |
| ADediting_501835 | chr15_75353107_+ | intronic |
| ADediting_501836 | chr15_75353112_+ | intronic |
| ADediting_501837 | chr15_75353132_+ | intronic |
| ADediting_501838 | chr15_75353274_+ | intronic |
| ADediting_501839 | chr15_75353280_+ | intronic |
| ADediting_501840 | chr15_75353305_+ | intronic |
| ADediting_501841 | chr15_75353311_+ | intronic |
| ADediting_501842 | chr15_75353322_+ | intronic |
| ADediting_501843 | chr15_75353323_+ | intronic |
| ADediting_501844 | chr15_75353335_+ | intronic |
| ADediting_501845 | chr15_75353337_+ | intronic |
| ADediting_501846 | chr15_75353347_+ | intronic |
| ADediting_501847 | chr15_75353348_+ | intronic |
| ADediting_501848 | chr15_75353351_+ | intronic |
| ADediting_501849 | chr15_75353355_+ | intronic |
| ADediting_501850 | chr15_75353361_+ | intronic |
| ADediting_501851 | chr15_75353363_+ | intronic |
| ADediting_501852 | chr15_75353371_+ | intronic |
| ADediting_501853 | chr15_75353374_+ | intronic |
| ADediting_501854 | chr15_75353409_+ | intronic |
| ADediting_501855 | chr15_75353411_+ | intronic |
| ADediting_501856 | chr15_75353415_+ | intronic |
| ADediting_501857 | chr15_75353426_+ | intronic |
| ADediting_501858 | chr15_75353435_+ | intronic |
| ADediting_501859 | chr15_75353443_+ | intronic |
| ADediting_501860 | chr15_75353447_+ | intronic |
| ADediting_501861 | chr15_75353448_+ | intronic |
| ADediting_501862 | chr15_75353461_+ | intronic |
| ADediting_501863 | chr15_75353477_+ | intronic |
| ADediting_501864 | chr15_75353478_+ | intronic |
| ADediting_501865 | chr15_75353486_+ | intronic |
| ADediting_501866 | chr15_75353487_+ | intronic |
| ADediting_501867 | chr15_75353488_+ | intronic |
| ADediting_501868 | chr15_75353500_+ | intronic |
| ADediting_501869 | chr15_75353502_+ | intronic |
| ADediting_501870 | chr15_75353517_+ | intronic |
| ADediting_501871 | chr15_75353745_+ | exonic |
| ADediting_501872 | chr15_75353746_+ | exonic |
| ADediting_1540245 | chr15_75349591_+ | intronic |
| ADediting_1540246 | chr15_75349596_+ | intronic |
| ADediting_1540247 | chr15_75349636_+ | intronic |
| ADediting_1540248 | chr15_75349637_+ | intronic |
| ADediting_1540249 | chr15_75349656_+ | intronic |
| ADediting_1540250 | chr15_75349734_+ | intronic |
| ADediting_1540251 | chr15_75351361_+ | UTR3 |
| ADediting_1540252 | chr15_75351531_+ | intronic |
| ADediting_1540253 | chr15_75351678_+ | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_501743 | chr15_75349552_+ | SINE | Alu | Name=AluSg |
| ADediting_501744 | chr15_75349560_+ | SINE | Alu | Name=AluSg |
| ADediting_501745 | chr15_75349561_+ | SINE | Alu | Name=AluSg |
| ADediting_501746 | chr15_75349566_+ | SINE | Alu | Name=AluSg |
| ADediting_501747 | chr15_75349578_+ | SINE | Alu | Name=AluSg |
| ADediting_501748 | chr15_75349604_+ | SINE | Alu | Name=AluSg |
| ADediting_501749 | chr15_75349618_+ | SINE | Alu | Name=AluSg |
| ADediting_501750 | chr15_75349627_+ | SINE | Alu | Name=AluSg |
| ADediting_501751 | chr15_75349638_+ | SINE | Alu | Name=AluSg |
| ADediting_501752 | chr15_75349649_+ | SINE | Alu | Name=AluSg |
| ADediting_501753 | chr15_75349655_+ | SINE | Alu | Name=AluSg |
| ADediting_501754 | chr15_75349658_+ | SINE | Alu | Name=AluSg |
| ADediting_501755 | chr15_75349667_+ | SINE | Alu | Name=AluSg |
| ADediting_501756 | chr15_75349693_+ | SINE | Alu | Name=AluSg |
| ADediting_501757 | chr15_75349694_+ | SINE | Alu | Name=AluSg |
| ADediting_501758 | chr15_75349703_+ | SINE | Alu | Name=AluSg |
| ADediting_501759 | chr15_75349720_+ | SINE | Alu | Name=AluSg |
| ADediting_501760 | chr15_75349723_+ | SINE | Alu | Name=AluSg |
| ADediting_501761 | chr15_75349724_+ | SINE | Alu | Name=AluSg |
| ADediting_501762 | chr15_75349742_+ | SINE | Alu | Name=AluSg |
| ADediting_501763 | chr15_75349755_+ | SINE | Alu | Name=AluSg |
| ADediting_501764 | chr15_75349759_+ | SINE | Alu | Name=AluSg |
| ADediting_501765 | chr15_75349768_+ | SINE | Alu | Name=AluSg |
| ADediting_501766 | chr15_75349771_+ | SINE | Alu | Name=AluSg |
| ADediting_501767 | chr15_75349784_+ | SINE | Alu | Name=AluSg |
| ADediting_501768 | chr15_75349794_+ | SINE | Alu | Name=AluSg |
| ADediting_501769 | chr15_75349798_+ | SINE | Alu | Name=AluSg |
| ADediting_501770 | chr15_75351295_+ | SINE | Alu | Name=AluJb |
| ADediting_501771 | chr15_75351324_+ | SINE | Alu | Name=AluJb |
| ADediting_501772 | chr15_75351329_+ | SINE | Alu | Name=AluJb |
| ADediting_501773 | chr15_75351340_+ | SINE | Alu | Name=AluJb |
| ADediting_501774 | chr15_75351343_+ | SINE | Alu | Name=AluJb |
| ADediting_501775 | chr15_75351345_+ | SINE | Alu | Name=AluJb |
| ADediting_501776 | chr15_75351350_+ | SINE | Alu | Name=AluJb |
| ADediting_501777 | chr15_75351355_+ | SINE | Alu | Name=AluJb |
| ADediting_501778 | chr15_75351362_+ | SINE | Alu | Name=AluJb |
| ADediting_501779 | chr15_75351368_+ | SINE | Alu | Name=AluJb |
| ADediting_501780 | chr15_75351375_+ | SINE | Alu | Name=AluJb |
| ADediting_501781 | chr15_75351388_+ | SINE | Alu | Name=AluJb |
| ADediting_501782 | chr15_75351394_+ | SINE | Alu | Name=AluJb |
| ADediting_501783 | chr15_75351406_+ | SINE | Alu | Name=AluJb |
| ADediting_501784 | chr15_75351415_+ | SINE | Alu | Name=AluJb |
| ADediting_501785 | chr15_75351450_+ | SINE | Alu | Name=AluJb |
| ADediting_501786 | chr15_75351451_+ | SINE | Alu | Name=AluJb |
| ADediting_501787 | chr15_75351461_+ | SINE | Alu | Name=AluJb |
| ADediting_501788 | chr15_75351523_+ | SINE | Alu | Name=AluJb |
| ADediting_501789 | chr15_75351534_+ | SINE | Alu | Name=AluJb |
| ADediting_501790 | chr15_75351545_+ | SINE | Alu | Name=AluJb |
| ADediting_501791 | chr15_75351686_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501792 | chr15_75351748_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501793 | chr15_75351749_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501794 | chr15_75351752_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501795 | chr15_75351762_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501796 | chr15_75351768_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501797 | chr15_75351788_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501798 | chr15_75351789_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501799 | chr15_75351796_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501800 | chr15_75351802_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501801 | chr15_75351805_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501802 | chr15_75351811_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501803 | chr15_75351819_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501804 | chr15_75351831_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501805 | chr15_75351884_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501806 | chr15_75351896_+ | SINE | Alu | Name=AluSx1 |
| ADediting_501807 | chr15_75352884_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501808 | chr15_75352885_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501809 | chr15_75352890_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501810 | chr15_75352907_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501811 | chr15_75352925_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501812 | chr15_75352930_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501813 | chr15_75352933_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501814 | chr15_75352941_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501815 | chr15_75352953_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501816 | chr15_75352954_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501817 | chr15_75352956_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501818 | chr15_75352963_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501819 | chr15_75352964_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501820 | chr15_75352969_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501821 | chr15_75352975_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501822 | chr15_75352994_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501823 | chr15_75353014_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501824 | chr15_75353020_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501825 | chr15_75353021_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501826 | chr15_75353026_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501827 | chr15_75353030_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501828 | chr15_75353047_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501829 | chr15_75353051_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501830 | chr15_75353052_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501831 | chr15_75353060_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501832 | chr15_75353061_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501833 | chr15_75353062_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501834 | chr15_75353092_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501835 | chr15_75353107_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501836 | chr15_75353112_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501837 | chr15_75353132_+ | SINE | Alu | Name=AluSq2 |
| ADediting_501838 | chr15_75353274_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501839 | chr15_75353280_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501840 | chr15_75353305_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501841 | chr15_75353311_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501842 | chr15_75353322_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501843 | chr15_75353323_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501844 | chr15_75353335_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501845 | chr15_75353337_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501846 | chr15_75353347_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501847 | chr15_75353348_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501848 | chr15_75353351_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501849 | chr15_75353355_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501850 | chr15_75353361_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501851 | chr15_75353363_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501852 | chr15_75353371_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501853 | chr15_75353374_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501854 | chr15_75353409_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501855 | chr15_75353411_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501856 | chr15_75353415_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501857 | chr15_75353426_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501858 | chr15_75353435_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501859 | chr15_75353443_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501860 | chr15_75353447_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501861 | chr15_75353448_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501862 | chr15_75353461_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501863 | chr15_75353477_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501864 | chr15_75353478_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501865 | chr15_75353486_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501866 | chr15_75353487_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501867 | chr15_75353488_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501868 | chr15_75353500_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501869 | chr15_75353502_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_501870 | chr15_75353517_+ | SINE | Alu | Name=AluYh3a3 |
| ADediting_1540245 | chr15_75349591_+ | SINE | Alu | Name=AluSg |
| ADediting_1540246 | chr15_75349596_+ | SINE | Alu | Name=AluSg |
| ADediting_1540247 | chr15_75349636_+ | SINE | Alu | Name=AluSg |
| ADediting_1540248 | chr15_75349637_+ | SINE | Alu | Name=AluSg |
| ADediting_1540249 | chr15_75349656_+ | SINE | Alu | Name=AluSg |
| ADediting_1540250 | chr15_75349734_+ | SINE | Alu | Name=AluSg |
| ADediting_1540251 | chr15_75351361_+ | SINE | Alu | Name=AluJb |
| ADediting_1540252 | chr15_75351531_+ | SINE | Alu | Name=AluJb |
| ADediting_1540253 | chr15_75351678_+ | SINE | Alu | Name=AluSx1 |
Top |
RNA A-to-I editing events in the alternative splicing sites for NEIL1 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A5SS | ADediting_501780 | chr15_75351375_+ | 75351374:75351382 | 5ss | 2e | CAGGTGATT | 5.95 | CGGGTGATT | 3.51 |
| ES | ADediting_501770 | chr15_75351295_+ | 75351281:75351303 | 3ss | 6i | TTTTTTTTTTTTTGAGACAGGGT | 4.19 | TTTTTTTTTTTTTGGGACAGGGT | 8.29 |
| ES | ADediting_501770 | chr15_75351295_+ | 75351281:75351303 | 3ss | 6i | TTTTTTTTTTTTTGAGACAGGGT | 4.19 | TTTTTTTTTTTTTGGGACAGGGT | 8.29 |
| ES | ADediting_501770 | chr15_75351295_+ | 75351281:75351303 | 3ss | 6i | TTTTTTTTTTTTTGAGACAGGGT | 4.19 | TTTTTTTTTTTTTGGGACAGGGT | 8.29 |
| ES | ADediting_501780 | chr15_75351375_+ | 75351374:75351382 | 5ss | 2e | CAGGTGATT | 5.95 | CGGGTGATT | 3.51 |
| ES | ADediting_501780 | chr15_75351375_+ | 75351374:75351382 | 5ss | 2e | CAGGTGATT | 5.95 | CGGGTGATT | 3.51 |
| ES | ADediting_501780 | chr15_75351375_+ | 75351374:75351382 | 5ss | 2e | CAGGTGATT | 5.95 | CGGGTGATT | 3.51 |
| ES | ADediting_501780 | chr15_75351375_+ | 75351374:75351382 | 5ss | 2e | CAGGTGATT | 5.95 | CGGGTGATT | 3.51 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for NEIL1 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for NEIL1 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
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Top |
The effects of the RNA editing to the miRNA binding sites for NEIL1 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_501807 | chr15_75352884_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-513a-5p | chr15 | 75352879 | 75352885 | 7mer-m8 | 75352869 | 75352886 | 152 | -17.32 |
| ADediting_501807 | chr15_75352884_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-638 | chr15 | 75352884 | 75352890 | 7mer-1a | 75352864 | 75352890 | 154 | -31.53 |
| ADediting_501808 | chr15_75352885_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-8052 | chr15 | 75352884 | 75352890 | 7mer-1a | 75352872 | 75352890 | 148 | -29.06 |
| ADediting_501809 | chr15_75352890_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-371a-3p | chr15 | 75352889 | 75352895 | 7mer-m8 | 75352874 | 75352896 | 144 | -15.05 |
| ADediting_501810 | chr15_75352907_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-941 | chr15 | 75352903 | 75352909 | 7mer-m8 | 75352888 | 75352910 | 144 | -26.68 |
| ADediting_501811 | chr15_75352925_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4726-3p | chr15 | 75352920 | 75352926 | 7mer-m8 | 75352899 | 75352927 | 145 | -30.53 |
| ADediting_501813 | chr15_75352933_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4732-3p | chr15 | 75352927 | 75352933 | 7mer-m8 | 75352914 | 75352934 | 150 | -19.39 |
| ADediting_501814 | chr15_75352941_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6878-3p | chr15 | 75352938 | 75352944 | 7mer-m8 | 75352923 | 75352945 | 150 | -19.22 |
| ADediting_501816 | chr15_75352954_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-3190-5p | chr15 | 75352948 | 75352954 | 7mer-m8 | 75352936 | 75352955 | 150 | -18.87 |
| ADediting_501817 | chr15_75352956_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-1306-3p | chr15 | 75352950 | 75352956 | 7mer-m8 | 75352940 | 75352957 | 156 | -25.84 |
| ADediting_501818 | chr15_75352963_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6511a-3p | chr15 | 75352957 | 75352963 | 7mer-m8 | 75352943 | 75352963 | 145 | -15 |
| ADediting_501818 | chr15_75352963_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6511b-3p | chr15 | 75352957 | 75352963 | 7mer-m8 | 75352942 | 75352963 | 140 | -13.48 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_501807 | chr15_75352884_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-10399-5p | chr15 | 75352880 | 75352886 | 7mer-m8 | 75352866 | 75352887 | 144 | -10.52 |
| ADediting_501807 | chr15_75352884_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-7151-3p | chr15 | 75352878 | 75352885 | 8mer-1a | 75352869 | 75352885 | 146 | -17.62 |
| ADediting_501808 | chr15_75352885_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-10399-5p | chr15 | 75352880 | 75352886 | 7mer-m8 | 75352866 | 75352887 | 144 | -10.52 |
| ADediting_501808 | chr15_75352885_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-5089-5p | chr15 | 75352884 | 75352890 | 7mer-m8 | 75352872 | 75352891 | 146 | -13.24 |
| ADediting_501809 | chr15_75352890_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-5089-5p | chr15 | 75352884 | 75352890 | 7mer-m8 | 75352872 | 75352891 | 146 | -13.24 |
| ADediting_501809 | chr15_75352890_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-512-3p | chr15 | 75352889 | 75352895 | 7mer-m8 | 75352875 | 75352896 | 149 | -15 |
| ADediting_501809 | chr15_75352890_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6506-5p | chr15 | 75352885 | 75352891 | 7mer-m8 | 75352870 | 75352892 | 144 | -16.21 |
| ADediting_501811 | chr15_75352925_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6790-3p | chr15 | 75352924 | 75352930 | 7mer-1a | 75352907 | 75352930 | 140 | -30.28 |
| ADediting_501814 | chr15_75352941_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6843-3p | chr15 | 75352938 | 75352944 | 7mer-m8 | 75352926 | 75352945 | 152 | -20.97 |
| ADediting_501814 | chr15_75352941_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-6848-3p | chr15 | 75352938 | 75352944 | 7mer-m8 | 75352928 | 75352945 | 142 | -15.48 |
| ADediting_501815 | chr15_75352953_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4435 | chr15 | 75352947 | 75352954 | 8mer-1a | 75352931 | 75352954 | 141 | -16.23 |
| ADediting_501815 | chr15_75352953_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4781-3p | chr15 | 75352951 | 75352957 | 7mer-m8 | 75352937 | 75352958 | 140 | -14.54 |
| ADediting_501816 | chr15_75352954_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4716-5p | chr15 | 75352953 | 75352959 | 7mer-m8 | 75352939 | 75352960 | 140 | -11.3 |
| ADediting_501816 | chr15_75352954_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4781-3p | chr15 | 75352951 | 75352957 | 7mer-m8 | 75352937 | 75352958 | 140 | -14.54 |
| ADediting_501817 | chr15_75352956_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4716-5p | chr15 | 75352953 | 75352959 | 7mer-m8 | 75352939 | 75352960 | 140 | -11.3 |
| ADediting_501817 | chr15_75352956_+ | ENSG00000140398.14 | ENST00000567959.5 | NEIL1-217 | hsa-miR-4781-3p | chr15 | 75352951 | 75352957 | 7mer-m8 | 75352937 | 75352958 | 140 | -14.54 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337758 | chr7_5495892_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-589-5p | chr15 | 75355789 | 75355795 | 7mer-m8 | 75355776 | 75355796 | 162 | -28.85 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-151a-3p | chr15 | 75355463 | 75355469 | 7mer-m8 | 75355450 | 75355470 | 149 | -22.41 |
| ADediting_1391023 | chr8_140732605_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-151a-3p | chr15 | 75356148 | 75356154 | 7mer-m8 | 75356132 | 75356155 | 147 | -20.42 |
| ADediting_1471003 | chr9_63819626_+ | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-4477b | chr15 | 75355355 | 75355361 | 7mer-m8 | 75355344 | 75355362 | 152 | -13.16 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-556-3p | chr15 | 75355111 | 75355117 | 7mer-m8 | 75355098 | 75355118 | 143 | -14.74 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000140398.14 | ENST00000564784.5 | NEIL1-206 | hsa-miR-556-3p | chr15 | 75355111 | 75355117 | 7mer-m8 | 75355098 | 75355118 | 143 | -14.74 |
| ADediting_1596844 | chr1_162342605_+ | ENSG00000140398.14 | ENST00000569035.5 | NEIL1-221 | hsa-miR-556-3p | chr15 | 75355111 | 75355117 | 7mer-m8 | 75355098 | 75355118 | 143 | -14.74 |
| ADediting_291761 | chr11_93733708_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-1304-3p | chr15 | 75356189 | 75356195 | 7mer-m8 | 75356177 | 75356196 | 142 | -17.63 |
| ADediting_291761 | chr11_93733708_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-1304-3p | chr15 | 75356791 | 75356798 | 8mer-1a | 75356777 | 75356798 | 151 | -23.85 |
| ADediting_496066 | chr15_66496985_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-4512 | chr15 | 75356580 | 75356587 | 8mer-1a | 75356566 | 75356587 | 159 | -29.99 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-589-3p | chr15 | 75356867 | 75356874 | 8mer-1a | 75356851 | 75356874 | 140 | -17.03 |
| ADediting_496066 | chr15_66496985_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-4512 | chr15 | 75355133 | 75355140 | 8mer-1a | 75355119 | 75355140 | 153 | -19.43 |
| ADediting_496066 | chr15_66496985_- | ENSG00000140398.14 | ENST00000355059.9 | NEIL1-201 | hsa-miR-4512 | chr15 | 75355555 | 75355561 | 7mer-m8 | 75355541 | 75355562 | 140 | -16.48 |
| ADediting_496066 | chr15_66496985_- | ENSG00000140398.14 | ENST00000564784.5 | NEIL1-206 | hsa-miR-4512 | chr15 | 75355133 | 75355140 | 8mer-1a | 75355119 | 75355140 | 153 | -19.43 |
| ADediting_496066 | chr15_66496985_- | ENSG00000140398.14 | ENST00000569035.5 | NEIL1-221 | hsa-miR-4512 | chr15 | 75355133 | 75355140 | 8mer-1a | 75355119 | 75355140 | 153 | -19.43 |
| Differentially expressed gene-miRNA network |
| Differentially expressed lncRNA-miRNA network |
 |
Top |
The effects of the RNA editing to the stability of the RNA structures for NEIL1 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000355059.9 | protein_coding |  |  |
| ENST00000567959.5 | lncRNA |  |  |
| ENST00000564784.5 | protein_coding |  |  |
| ENST00000569035.5 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_501871 | ENST00000355059.9 | chr15_75353745_+ | 1182 | -1597.50 | -1597.50 | -1598.10 |
| ADediting_501872 | ENST00000355059.9 | chr15_75353746_+ | 1183 | -1597.50 | -1597.50 | -1598.10 |
| ADediting_501871 | ENST00000564784.5 | chr15_75353745_+ | 1354 | -890.80 | -890.80 | -892.20 |
| ADediting_501872 | ENST00000564784.5 | chr15_75353746_+ | 1355 | -890.80 | -890.80 | -892.20 |
| ADediting_501871 | ENST00000569035.5 | chr15_75353745_+ | 1136 | -803.80 | -803.80 | -805.20 |
| ADediting_501872 | ENST00000569035.5 | chr15_75353746_+ | 1137 | -803.80 | -803.80 | -805.20 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_501807 | ENST00000567959.5 | chr15_75352884_+ | 722 | -328.00 | -325.40 | -330.20 |
| ADediting_501808 | ENST00000567959.5 | chr15_75352885_+ | 723 | -325.60 | -325.40 | -330.20 |
| ADediting_501809 | ENST00000567959.5 | chr15_75352890_+ | 728 | -325.40 | -325.40 | -330.20 |
| ADediting_501810 | ENST00000567959.5 | chr15_75352907_+ | 745 | -325.00 | -325.40 | -330.20 |
| ADediting_501811 | ENST00000567959.5 | chr15_75352925_+ | 763 | -324.40 | -325.40 | -330.20 |
| ADediting_501812 | ENST00000567959.5 | chr15_75352930_+ | 768 | -324.70 | -325.40 | -330.20 |
| ADediting_501813 | ENST00000567959.5 | chr15_75352933_+ | 771 | -326.50 | -325.40 | -330.20 |
| ADediting_501814 | ENST00000567959.5 | chr15_75352941_+ | 779 | -325.40 | -325.40 | -330.20 |
| ADediting_501815 | ENST00000567959.5 | chr15_75352953_+ | 791 | -325.30 | -325.40 | -330.20 |
| ADediting_501816 | ENST00000567959.5 | chr15_75352954_+ | 792 | -325.40 | -325.40 | -330.20 |
| ADediting_501817 | ENST00000567959.5 | chr15_75352956_+ | 794 | -325.70 | -325.40 | -330.20 |
| ADediting_501818 | ENST00000567959.5 | chr15_75352963_+ | 801 | -325.40 | -325.40 | -330.20 |
Top |
Relation with ADAR for NEIL1 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | ADediting_501765 | chr15_75349768_+ | 2.69730453760333e-12 | 0.383423630091515 | 5.83333000561219e-13 | 0.394091931121615 | 0.000311578692074035 | 0.2034534516247 |
| DLPFC | ADediting_501766 | chr15_75349771_+ | 3.24751807712858e-09 | 0.328125399983822 | 1.16790770060759e-08 | 0.316878036079218 | 0.00137068448410263 | 0.181017788215469 |
| DLPFC | ADediting_501771 | chr15_75351324_+ | 1.69272719481134e-07 | 0.291749825538549 | 5.20249174626238e-17 | 0.451944500510901 | 0.00350333414206004 | 0.165354564714027 |
| FP | ADediting_501771 | chr15_75351324_+ | 0.012076053251011 | 0.187772489228144 | 0.0535486124012927 | 0.144950963833391 | 1.01415132857422e-06 | 0.356815811741069 |
| DLPFC | ADediting_501772 | chr15_75351329_+ | 9.61147682414339e-07 | 0.27403125771193 | 8.37410519186629e-12 | 0.375273962845405 | 0.860832176002397 | 0.00999735735628127 |
| DLPFC | ADediting_501773 | chr15_75351340_+ | 3.36038823259669e-06 | 0.260441201693377 | 3.85172467469976e-15 | 0.426608154141492 | 0.042448004277812 | 0.115326287226256 |
| FP | ADediting_501773 | chr15_75351340_+ | 0.109127556508906 | 0.120495462104708 | 0.542993794791994 | 0.0458927112591926 | 1.41979925426588e-05 | 0.319058428708586 |
| DLPFC | ADediting_501780 | chr15_75351375_+ | 2.80628418478466e-07 | 0.286717059759927 | 6.25045626913275e-11 | 0.360227547771784 | 0.623029982318785 | 0.0280265028252964 |
| CER | ADediting_501781 | chr15_75351388_+ | 0.00085221878503163 | 0.269519584437093 | 8.16199001426062e-05 | 0.316026707542494 | 0.2570028538881 | 0.0931279473512688 |
| DLPFC | ADediting_501785 | chr15_75351450_+ | 2.03168946275731e-08 | 0.311865078682231 | 2.70730256604438e-12 | 0.383397379983673 | 0.130264524568953 | 0.0861241865881247 |
| DLPFC | ADediting_501788 | chr15_75351523_+ | 3.5229560747984e-10 | 0.346622071344072 | 5.68631481035404e-16 | 0.438130029882424 | 0.00640021906415922 | 0.154549917543782 |
| DLPFC | ADediting_501790 | chr15_75351545_+ | 8.79076781326756e-09 | 0.319414818107266 | 3.85793584164105e-11 | 0.363911443678464 | 0.138580157940471 | 0.0843115333047988 |
| DLPFC | ADediting_501791 | chr15_75351686_+ | 6.8119107769011e-09 | 0.321672115541824 | 1.07109340974658e-11 | 0.373473005337623 | 0.00622192910030419 | 0.155071279191969 |
| CER | ADediting_501792 | chr15_75351748_+ | 0.00145684803880968 | 0.257655487426318 | 8.96072331901902e-07 | 0.388535257882288 | 0.0016423369487787 | 0.254927827077999 |
| DLPFC | ADediting_501795 | chr15_75351762_+ | 7.81331006144646e-06 | 0.250835113580204 | 2.11835061279428e-09 | 0.331779872749452 | 0.00318601533012237 | 0.166999899035002 |
| DLPFC | ADediting_501805 | chr15_75351884_+ | 1.89979338380455e-07 | 0.290609479544036 | 5.28792733521433e-12 | 0.378608421114561 | 0.662455965551033 | 0.0248896528496223 |
| DLPFC | ADediting_501806 | chr15_75351896_+ | 2.84292745435709e-07 | 0.286586607393438 | 7.23165624731611e-11 | 0.35910496500342 | 0.417809457462472 | 0.046179826938322 |
| CER | ADediting_501806 | chr15_75351896_+ | 0.00250913045570568 | 0.24504117596142 | 3.6816968198941e-05 | 0.330197718160185 | 0.555671122634373 | 0.0484921351227448 |
| CER | ADediting_501807 | chr15_75352884_+ | 1.20458913538328e-10 | 0.494979813845512 | 6.82734227365608e-13 | 0.54326310958305 | 0.696177783115577 | 0.0321436395948791 |
| TCX | ADediting_501807 | chr15_75352884_+ | 7.95748337391441e-08 | 0.421255421971047 | 1.67405817011527e-09 | 0.467173114668208 | 0.401225855138505 | -0.0690351841310999 |
| DLPFC | ADediting_501808 | chr15_75352885_+ | 0.0336568374582096 | 0.120690362079323 | 5.85104119484837e-08 | 0.302019844592843 | 0.444347495741502 | 0.0435972993574539 |
| CER | ADediting_501808 | chr15_75352885_+ | 4.57645909680149e-05 | 0.326394457012941 | 6.12336062745829e-06 | 0.359794828052004 | 0.0473459629545326 | 0.162209878264345 |
| TCX | ADediting_501808 | chr15_75352885_+ | 2.18442793763691e-06 | 0.375550237889245 | 2.01387969902625e-05 | 0.340490034522267 | 0.829037682411993 | 0.0177784269385829 |
| DLPFC | ADediting_501809 | chr15_75352890_+ | 0.016410829360382 | 0.136205363591492 | 7.69998153028731e-09 | 0.320589779948022 | 0.386261441610128 | -0.0493786398512781 |
| CER | ADediting_501809 | chr15_75352890_+ | 2.45535330458797e-07 | 0.406462855745801 | 1.16570358220729e-11 | 0.51772302134663 | 0.438307076018517 | 0.0637518907736052 |
| TCX | ADediting_501809 | chr15_75352890_+ | 6.73541769982203e-07 | 0.392580129513668 | 7.11224029540144e-14 | 0.562182054827991 | 0.0171219221893953 | -0.194424376685084 |
| CER | ADediting_501810 | chr15_75352907_+ | 0.00195089678203765 | 0.250957772638113 | 3.33990752354161e-09 | 0.459443077975511 | 0.019294408349494 | 0.19088010987882 |
| CER | ADediting_501811 | chr15_75352925_+ | 0.00394275504447123 | 0.234051556639704 | 1.37056657751371e-07 | 0.414206210620314 | 0.109810740329486 | 0.131093992728059 |
| TCX | ADediting_501811 | chr15_75352925_+ | 0.00311363883731618 | 0.239852860239108 | 7.97644273847881e-06 | 0.355615723694503 | 0.163835398947484 | -0.11426296851748 |
| CER | ADediting_501812 | chr15_75352930_+ | 0.000117188153989121 | 0.309346874085879 | 0.000143942042860054 | 0.305477353973579 | 0.482549259321357 | -0.0577704360279068 |
| TCX | ADediting_501812 | chr15_75352930_+ | 5.29326863039303e-06 | 0.362072624385646 | 3.03967011951531e-08 | 0.433351190295737 | 0.00931256850440111 | -0.211677816298508 |
| CER | ADediting_501813 | chr15_75352933_+ | 2.55450830844379e-06 | 0.373210750854829 | 1.7199713597792e-10 | 0.491359233444014 | 0.611932635702169 | -0.0417534492911949 |
| TCX | ADediting_501813 | chr15_75352933_+ | 0.0167501407569194 | 0.195069643375876 | 4.26334518027888e-05 | 0.327638976467754 | 0.995367358525047 | -0.000478072526901303 |
| DLPFC | ADediting_501814 | chr15_75352941_+ | 0.0101482645688819 | 0.145815861367664 | 4.84487108718281e-09 | 0.324659389610864 | 0.67824147652384 | 0.0236549537372965 |
| CER | ADediting_501814 | chr15_75352941_+ | 1.52891204844818e-09 | 0.468174005865088 | 4.17554844205205e-12 | 0.5272124068803 | 0.872988199759087 | 0.0131623859889169 |
| TCX | ADediting_501814 | chr15_75352941_+ | 1.02549501565576e-08 | 0.446463115543393 | 7.16993973948025e-12 | 0.522251868074787 | 0.388980259922134 | -0.0708427830164296 |
| DLPFC | ADediting_501815 | chr15_75352953_+ | 1.28901021704198e-06 | 0.270910636095362 | 4.24656235137407e-10 | 0.345112538205033 | 0.792620175659838 | -0.0149919926055701 |
| TCX | ADediting_501815 | chr15_75352953_+ | 8.92077421639225e-05 | 0.314399651360433 | 0.000143368870159011 | 0.30555294764478 | 0.952027457490839 | -0.00495352848502482 |
| DLPFC | ADediting_501816 | chr15_75352954_+ | 0.018495387768227 | 0.133724959854633 | 1.04865883638711e-08 | 0.317842521730432 | 0.455796605583951 | 0.0425103872004084 |
| CER | ADediting_501816 | chr15_75352954_+ | 7.25361470933213e-11 | 0.500063871815136 | 9.82773383125567e-09 | 0.446965492287733 | 0.154048488383088 | -0.116960067412972 |
| TCX | ADediting_501816 | chr15_75352954_+ | 0.000182919074325895 | 0.300899172962558 | 1.30771180299919e-09 | 0.46989113686857 | 0.0741440319974681 | -0.146242175413216 |
| DLPFC | ADediting_501817 | chr15_75352956_+ | 4.65048478247014e-05 | 0.229144968518048 | 6.62761709010913e-08 | 0.300835537399678 | 0.810743706782278 | -0.0136553252470986 |
| CER | ADediting_501818 | chr15_75352963_+ | 0.00028774966485492 | 0.292031057676797 | 1.76196208464049e-05 | 0.342721305221225 | 0.120333272381916 | 0.127381003578453 |
| TCX | ADediting_501818 | chr15_75352963_+ | 0.0471325715087767 | 0.162364407489192 | 1.81063028339662e-06 | 0.378331925530109 | 0.639682960492681 | -0.0385317797575041 |
| CER | ADediting_501819 | chr15_75352964_+ | 6.99967253327766e-10 | 0.476665122737302 | 9.33019588514559e-15 | 0.578207010275106 | 0.181546594162494 | 0.109672715113316 |
| TCX | ADediting_501819 | chr15_75352964_+ | 0.0669291644728339 | 0.150001656241271 | 2.94129421424505e-06 | 0.371087476042804 | 0.196913951100651 | -0.105949720267552 |
| DLPFC | ADediting_501820 | chr15_75352969_+ | 0.00496861983087198 | 0.159168616287393 | 6.98457621941446e-09 | 0.321451380653441 | 0.508853858442956 | 0.0376597114518464 |
| CER | ADediting_501820 | chr15_75352969_+ | 1.80113274949143e-08 | 0.439735625681434 | 1.32283366265847e-07 | 0.414670757619585 | 0.331565127458704 | -0.0798202074329652 |
| TCX | ADediting_501820 | chr15_75352969_+ | 8.70026095403508e-05 | 0.314858722826439 | 2.16599906891665e-11 | 0.511851175104244 | 0.0067914328270106 | -0.220141062695014 |
| DLPFC | ADediting_501822 | chr15_75352994_+ | 0.011315485639867 | 0.143686727197199 | 3.81224021994921e-09 | 0.326741505008842 | 0.313032084613855 | 0.0574853760878512 |
| CER | ADediting_501822 | chr15_75352994_+ | 0.000237758217934104 | 0.295801445024582 | 1.70357320270648e-06 | 0.379229756654842 | 0.584491671254729 | 0.0450027794061195 |
| TCX | ADediting_501822 | chr15_75352994_+ | 0.00133314365863967 | 0.259656661858816 | 9.28004659923801e-06 | 0.353196098933436 | 0.0901617707289825 | -0.138849534282362 |
| CER | ADediting_501824 | chr15_75353020_+ | 0.0103684342699691 | 0.208727619906569 | 1.44384260436955e-05 | 0.34601466267651 | 0.70953350157304 | 0.0306624359641867 |
| TCX | ADediting_501824 | chr15_75353020_+ | 0.0768045443251715 | 0.144930550542904 | 4.45892078992978e-05 | 0.326851980811602 | 0.0940956622603715 | -0.137196575684839 |
| CER | ADediting_501825 | chr15_75353021_+ | 2.2951047787505e-08 | 0.436795254639772 | 3.25242157931262e-06 | 0.369563974919442 | 0.936464357106888 | 0.00656349533906641 |
| TCX | ADediting_501825 | chr15_75353021_+ | 1.06353486785917e-05 | 0.351000049834736 | 0.000117124581546717 | 0.309357014802232 | 0.619554287773215 | 0.0408624921690374 |
| CER | ADediting_501826 | chr15_75353026_+ | 0.000164038503795058 | 0.302989866584673 | 2.96962740681766e-07 | 0.403894425965682 | 0.142756871455791 | 0.120237123713364 |
| TCX | ADediting_501826 | chr15_75353026_+ | 0.0519992994864183 | 0.158976084845384 | 4.45358658943289e-05 | 0.326873011980007 | 0.479397443855918 | -0.058186322013637 |
| DLPFC | ADediting_501828 | chr15_75353047_+ | 9.37052161666327e-08 | 0.297516309331097 | 8.64674217473673e-12 | 0.375040154724369 | 0.621165165907566 | 0.0281769096805514 |
| DLPFC | ADediting_501829 | chr15_75353051_+ | 3.81529281031449e-05 | 0.231655073475681 | 3.9045873383623e-11 | 0.363820245955431 | 0.610009522396211 | -0.029080805166863 |
| DLPFC | ADediting_501831 | chr15_75353060_+ | 0.023886773738318 | 0.128287158593173 | 7.85448040007656e-10 | 0.340085315859289 | 0.247412375708223 | 0.0658884888555592 |
| CER | ADediting_501831 | chr15_75353060_+ | 2.96862761764069e-09 | 0.460775627369955 | 1.08038389703889e-07 | 0.41731063639874 | 0.748051766850776 | 0.0264432542509527 |
| TCX | ADediting_501831 | chr15_75353060_+ | 1.65221232915888e-05 | 0.34378907112396 | 3.35043177441885e-06 | 0.369112644988489 | 0.784385168818807 | -0.0225256784340855 |
| CER | ADediting_501839 | chr15_75353280_+ | 5.33295629216571e-07 | 0.395848728456944 | 0.000148447207565954 | 0.304892767222953 | 0.461945021105121 | 0.0605165648376817 |
| TCX | ADediting_501839 | chr15_75353280_+ | 2.55086250428971e-06 | 0.373232182872627 | 1.42121083344187e-06 | 0.381883673015636 | 0.794722133018628 | 0.0214206601087517 |
| FP | ADediting_501839 | chr15_75353280_+ | 0.00225067437356275 | 0.227572370748276 | 0.0545827877460126 | 0.144335230650677 | 2.94861680510636e-06 | 0.342137144818933 |
| STG | ADediting_501839 | chr15_75353280_+ | 0.0365973158291118 | 0.228460271889089 | 0.000211048116610931 | 0.393733461070241 | 0.79226173518306 | 0.0291674715593755 |
| TCX | ADediting_501840 | chr15_75353305_+ | 1.27646832496848e-06 | 0.38344576763311 | 7.79357111073914e-11 | 0.499349265096166 | 0.0822895281504833 | -0.142338093834782 |
| DLPFC | ADediting_501842 | chr15_75353322_+ | 0.00417697632448995 | 0.162267340382615 | 2.05869598855323e-09 | 0.332022491017287 | 0.073859226229059 | 0.101669796190652 |
| CER | ADediting_501842 | chr15_75353322_+ | 0.000356490790798566 | 0.287735866969217 | 1.69524189619997e-06 | 0.379301860732746 | 0.554013300623937 | 0.0486954421713185 |
| TCX | ADediting_501842 | chr15_75353322_+ | 1.70490256760625e-07 | 0.411330030122415 | 2.00606303823707e-16 | 0.606293731898877 | 0.000366047897211189 | -0.287200680609339 |
| STG | ADediting_501842 | chr15_75353322_+ | 0.00653766416879422 | 0.294524819362139 | 0.000427300841970342 | 0.375791104693806 | 0.60701137675767 | 0.0569269940973878 |
| TCX | ADediting_501843 | chr15_75353323_+ | 3.89122281806434e-09 | 0.45770691714312 | 8.74565242565936e-11 | 0.498198659062065 | 0.335000979759846 | -0.0792566966059164 |
| STG | ADediting_501843 | chr15_75353323_+ | 0.0154486896852345 | 0.263488412569525 | 0.00292438909719881 | 0.320839947663163 | 0.258793697154004 | 0.124597040997527 |
| DLPFC | ADediting_501844 | chr15_75353335_+ | 4.64857009706088e-06 | 0.256791860288542 | 6.44189574182541e-10 | 0.341715867026819 | 0.00467711731103834 | 0.160254135246629 |
| TCX | ADediting_501844 | chr15_75353335_+ | 0.00667287830581772 | 0.220604373220666 | 2.74207239131525e-05 | 0.335270228411955 | 0.0169749923579287 | -0.194677920789777 |
| STG | ADediting_501844 | chr15_75353335_+ | 0.0043077004239159 | 0.308462071850254 | 0.0768081306172621 | 0.194137324127379 | 0.349972108460063 | -0.103252168308223 |
| DLPFC | ADediting_501847 | chr15_75353348_+ | 0.0338539646481819 | 0.120557683484521 | 2.22410127102837e-09 | 0.331365618508207 | 0.272381474513545 | 0.062530779501125 |
| CER | ADediting_501847 | chr15_75353348_+ | 5.42612020112731e-05 | 0.323381681442384 | 1.59932309787609e-07 | 0.412175150579833 | 0.0376961925454007 | -0.169865516660974 |
| TCX | ADediting_501847 | chr15_75353348_+ | 1.19958394030976e-07 | 0.415948819825402 | 1.53898657366191e-25 | 0.722956209005414 | 2.20732186218907e-06 | -0.375394952725645 |
| FP | ADediting_501847 | chr15_75353348_+ | 4.37120863010803e-05 | 0.301301717614372 | 6.29086859452324e-05 | 0.295298621880554 | 0.0418567450465747 | 0.15270544703231 |
| STG | ADediting_501847 | chr15_75353348_+ | 0.00294968437736663 | 0.320570206659441 | 0.000452320234229416 | 0.374298046110282 | 0.842993211050234 | -0.0219369037645266 |
| DLPFC | ADediting_501848 | chr15_75353351_+ | 0.0330874872750373 | 0.121077318721595 | 4.68655526914453e-08 | 0.304115744590304 | 0.118955214344979 | 0.0887388304589135 |
| CER | ADediting_501848 | chr15_75353351_+ | 2.96829177657366e-05 | 0.333914296497268 | 4.5026890977261e-08 | 0.428469620049153 | 0.648652327075325 | -0.0375030964490506 |
| TCX | ADediting_501848 | chr15_75353351_+ | 2.22357428672326e-06 | 0.375285641952335 | 2.13404089112263e-13 | 0.553139478281746 | 0.00399786138626529 | -0.233706210666849 |
| STG | ADediting_501848 | chr15_75353351_+ | 0.0236241360761193 | 0.246798906913798 | 0.00184679609785027 | 0.334896203112168 | 0.793923924641162 | -0.0289287882575451 |
| TCX | ADediting_501849 | chr15_75353355_+ | 5.5539830115098e-06 | 0.361322776653911 | 0.000511308804510787 | 0.280347040566534 | 0.121601837872722 | 0.126950628315849 |
| STG | ADediting_501849 | chr15_75353355_+ | 0.0075047207937407 | 0.289766133420531 | 0.00381199491852865 | 0.312424755119717 | 0.460254864691417 | -0.0816578777020858 |
| TCX | ADediting_501850 | chr15_75353361_+ | 4.39951157733759e-07 | 0.398516366954216 | 6.87579899137372e-06 | 0.357970086205896 | 0.49113382560514 | 0.056645028592265 |
| STG | ADediting_501850 | chr15_75353361_+ | 0.0207320355892855 | 0.252038325874329 | 0.00347572434994469 | 0.315383594129758 | 0.503071069060031 | -0.0740759563392562 |
| CER | ADediting_501851 | chr15_75353363_+ | 0.000105746408710695 | 0.311260333796648 | 4.06244836306311e-07 | 0.399614655008535 | 0.417424326014735 | 0.0666936963596234 |
| DLPFC | ADediting_501852 | chr15_75353371_+ | 0.001347603033086 | 0.181289777024499 | 6.48940014808392e-08 | 0.301036185976831 | 0.175652149112249 | 0.0771139738492572 |
| TCX | ADediting_501852 | chr15_75353371_+ | 0.0107639511837418 | 0.207690402785651 | 6.21802138164904e-05 | 0.32094858673468 | 0.00948787695752392 | -0.211168195355411 |
| CER | ADediting_501853 | chr15_75353374_+ | 9.41385539759226e-05 | 0.313410371770319 | 1.47139573476226e-10 | 0.492951218646775 | 0.20494024178445 | 0.104088605728675 |
| DLPFC | ADediting_501854 | chr15_75353409_+ | 3.06021260415456e-06 | 0.26148343725999 | 1.123247145764e-17 | 0.460480678001272 | 0.0214398019096297 | 0.130607214735976 |
| TCX | ADediting_501854 | chr15_75353409_+ | 3.15160281097019e-08 | 0.43290512844907 | 1.50917419412838e-12 | 0.536336594321268 | 0.0180025361765333 | -0.192943195205703 |
| DLPFC | ADediting_501856 | chr15_75353415_+ | 0.00016022131351935 | 0.212786045635821 | 1.64063563364235e-13 | 0.402647706791913 | 0.0218125523640354 | 0.130239461528431 |
| CER | ADediting_501856 | chr15_75353415_+ | 6.76302303003076e-05 | 0.319437550140649 | 9.99220188980161e-05 | 0.312309957261651 | 0.633323783760595 | -0.0392647236855606 |
| TCX | ADediting_501856 | chr15_75353415_+ | 1.27769140665801e-07 | 0.415125101216963 | 2.57166125450474e-10 | 0.487218741985397 | 0.156715910971014 | -0.116212528177143 |
| DLPFC | ADediting_501858 | chr15_75353435_+ | 3.61616523324587e-05 | 0.23233003255735 | 6.13129723875911e-14 | 0.409121161339158 | 0.0333381136127163 | 0.120906288501397 |
| CER | ADediting_501858 | chr15_75353435_+ | 2.96961775546232e-05 | 0.333906639276479 | 1.11607554521193e-11 | 0.518131165087869 | 0.191964648912653 | 0.107124896317123 |
| TCX | ADediting_501858 | chr15_75353435_+ | 0.000407668398729307 | 0.285011208624469 | 1.60184257023215e-15 | 0.591435453533319 | 0.000614635136944712 | -0.276496683675443 |
| STG | ADediting_501858 | chr15_75353435_+ | 0.00362602856804823 | 0.314030843445879 | 0.0278349748643211 | 0.240072165652782 | 0.655129174824696 | 0.0494443422460708 |
| CER | ADediting_501859 | chr15_75353443_+ | 0.000167556952489954 | 0.302583830102476 | 1.8888354630514e-11 | 0.513158533315372 | 0.018101994575072 | 0.192779880958357 |
| TCX | ADediting_501859 | chr15_75353443_+ | 0.180311194225703 | 0.109981889726937 | 8.43032208905186e-08 | 0.420514639705729 | 0.0598296513965336 | -0.154038628269755 |
| DLPFC | ADediting_501861 | chr15_75353448_+ | 0.000759284143026858 | 0.190264304891214 | 9.45015955087128e-11 | 0.357033569486308 | 0.172702181429247 | 0.0776424105044169 |
| CER | ADediting_501861 | chr15_75353448_+ | 0.000491451955461963 | 0.281168472990717 | 3.58211049228484e-08 | 0.431320548880766 | 0.425435051845536 | 0.0655553829152753 |
| TCX | ADediting_501861 | chr15_75353448_+ | 0.00544523819424401 | 0.225889239257351 | 1.23839647270708e-10 | 0.494699961526475 | 0.00243077598526754 | -0.245794770208165 |
| DLPFC | ADediting_501863 | chr15_75353477_+ | 3.35937999041511e-06 | 0.260444551219432 | 6.59157068067251e-15 | 0.423291754374384 | 0.366292012868028 | 0.0514859383265144 |
| CER | ADediting_501863 | chr15_75353477_+ | 0.000317335980338726 | 0.290077091470053 | 3.99833355659915e-11 | 0.505929109751173 | 0.0232580390536781 | 0.185220191991237 |
| TCX | ADediting_501863 | chr15_75353477_+ | 0.0138493289929598 | 0.200583203899032 | 3.64907896064189e-15 | 0.585329153973973 | 0.0066047032814612 | -0.220874128422683 |
| DLPFC | ADediting_501864 | chr15_75353478_+ | 2.52043571576465e-07 | 0.287794804199468 | 1.16137933077762e-17 | 0.46029729523309 | 0.013340213941221 | 0.1404155647252 |
| CER | ADediting_501864 | chr15_75353478_+ | 1.68115567898572e-05 | 0.343501128668943 | 2.44729448143786e-10 | 0.487731977030971 | 0.0709725297761944 | 0.147856434940678 |
| TCX | ADediting_501864 | chr15_75353478_+ | 2.61819586939818e-05 | 0.336058030769867 | 1.11039171521114e-17 | 0.625776374714803 | 7.86665842175427e-05 | -0.316698530230491 |
| DLPFC | ADediting_501865 | chr15_75353486_+ | 5.94250956907898e-08 | 0.301872724497558 | 1.14686795835883e-16 | 0.447447362659236 | 0.0665246695917969 | 0.104350593130405 |
| CER | ADediting_501865 | chr15_75353486_+ | 0.000435107273409385 | 0.283678212628908 | 4.98256309072269e-08 | 0.427198893121873 | 0.0220803716006547 | 0.186808998687333 |
| TCX | ADediting_501865 | chr15_75353486_+ | 4.23043863008581e-06 | 0.365543459214788 | 3.24444855025067e-09 | 0.459771508941259 | 0.00330625258281635 | -0.238390761605698 |
| DLPFC | ADediting_501868 | chr15_75353500_+ | 4.22599467529889e-06 | 0.257869348713087 | 2.0710751705165e-15 | 0.430393268366213 | 0.048489772737504 | 0.112161025434156 |
| CER | ADediting_501868 | chr15_75353500_+ | 0.00022344793534296 | 0.29701681835324 | 7.77731984213411e-10 | 0.475533620149682 | 0.0272367047200943 | 0.180319246392099 |
| TCX | ADediting_501868 | chr15_75353500_+ | 4.06141578435366e-05 | 0.328487941821282 | 2.76874393420013e-18 | 0.634664111165368 | 2.81168235774655e-05 | -0.334842117421897 |
| TCX | ADediting_501872 | chr15_75353746_+ | 0.00151661790098693 | 0.25674358644627 | 2.47303454396772e-06 | 0.373696778453621 | 0.0386303820344976 | -0.169056697274573 |
| IFG | ADediting_501872 | chr15_75353746_+ | 0.300434632642878 | 0.215692464471476 | 0.0406424672861441 | 0.412130240906404 | 0.28960796514343 | 0.220463423555393 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.27904328722025e-08 | 0.316061353124243 | 4.18834291121777e-19 | 0.478028095647778 | 1.35891610164778e-14 | 0.418767541669906 |
| AC | 4.77115411912138e-11 | 0.400487638909306 | 1.67597610459145e-10 | 0.389890872752877 | 2.55153780945999e-15 | 0.472675645505754 |
| PCC | 0.000211592070063321 | 0.264997969589159 | 0.000161488055864216 | 0.269678409194039 | 5.17296046264812e-10 | 0.430357878725955 |
| CER | 0.170489222051062 | 0.11249726050357 | 3.8750988013891e-06 | 0.366891171522805 | 0.026842590175665 | 0.180776289155415 |
| FP | 3.59612714477472e-16 | 0.561393619327592 | 2.49833626642571e-14 | 0.530840142611079 | 5.70821458013388e-11 | 0.465756447906395 |
| IFG | 0.000264273349841707 | 0.667869033897632 | 1.28343793347387e-07 | 0.842380153866441 | 0.00428886462432096 | 0.551241095708031 |
| STG | 9.48834796586614e-09 | 0.576573779294497 | 2.24081053526559e-06 | 0.489959766471394 | 3.14943622585516e-05 | 0.437588930200467 |
Top |
Relation with AD stages for NEIL1 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_501792 | chr15_75351748_+ | 0.000523498234246054 | 0.328271336544339 |
| CER | ADediting_501794 | chr15_75351752_+ | 0.00119483730103794 | 0.307757373982491 |
| CER | ADediting_501810 | chr15_75352907_+ | 3.76829384834029e-05 | 0.385604650722244 |
| CER | ADediting_501859 | chr15_75353443_+ | 2.39653330996644e-05 | 0.394466338017659 |
| CER | ADediting_501861 | chr15_75353448_+ | 0.00092900701016035 | 0.314167450390008 |
| CER | ADediting_501863 | chr15_75353477_+ | 0.000127797919934205 | 0.360336252890478 |
| CER | ADediting_501864 | chr15_75353478_+ | 0.00126233708864845 | 0.306338420949252 |
| CER | ADediting_501868 | chr15_75353500_+ | 0.000944551562815433 | 0.313749103657642 |
| CER | ADediting_501872 | chr15_75353746_+ | 0.000269381565712488 | -0.343808005719063 |
| IFG | ADediting_501807 | chr15_75352884_+ | 0.0373752155885605 | 0.418428830972728 |
| IFG | ADediting_501820 | chr15_75352969_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_501822 | chr15_75352994_+ | 0.0354713369979928 | 0.422303326441651 |
| IFG | ADediting_501843 | chr15_75353323_+ | 0.0283516461372046 | 0.438449545622283 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 0.00046147713168602 | 0.331283326684702 |
| TCX | 0.0013609767017181 | 0.307168942949507 |
Top |
RelatedDrugs for NEIL1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| NEIL1 | Q96FI4 | DB01592 | Iron | Endonuclease 8-like 1 | small molecule | approved |
| NEIL1 | Q96FI4 | DB03754 | Tromethamine | Endonuclease 8-like 1 | small molecule | approved |
| NEIL1 | Q96FI4 | DB14488 | Ferrous gluconate | Endonuclease 8-like 1 | small molecule | approved |
| NEIL1 | Q96FI4 | DB14489 | Ferrous succinate | Endonuclease 8-like 1 | small molecule | approved |
| NEIL1 | Q96FI4 | DB14490 | Ferrous ascorbate | Endonuclease 8-like 1 | small molecule | approved |
| NEIL1 | Q96FI4 | DB14491 | Ferrous fumarate | Endonuclease 8-like 1 | small molecule | approved |
| NEIL1 | Q96FI4 | DB14501 | Ferrous glycine sulfate | Endonuclease 8-like 1 | small molecule | approved |
Top |
RelatedDiseases for NEIL1 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
| NEIL1 | C0015695 | Fatty Liver | 2 | CTD_human |
| NEIL1 | C0028754 | Obesity | 2 | CTD_human |
| NEIL1 | C0524620 | Metabolic Syndrome X | 2 | CTD_human |
| NEIL1 | C2711227 | Steatohepatitis | 2 | CTD_human |
| NEIL1 | C0020459 | Hyperinsulinism | 1 | CTD_human |
| NEIL1 | C0020473 | Hyperlipidemia | 1 | CTD_human |
| NEIL1 | C0021655 | Insulin Resistance | 1 | CTD_human |
| NEIL1 | C0242339 | Dyslipidemias | 1 | CTD_human |
| NEIL1 | C0271650 | Impaired glucose tolerance | 1 | CTD_human |
| NEIL1 | C0598784 | Dyslipoproteinemias | 1 | CTD_human |
| NEIL1 | C0920563 | Insulin Sensitivity | 1 | CTD_human |
| NEIL1 | C1257963 | Endogenous Hyperinsulinism | 1 | CTD_human |
| NEIL1 | C1257964 | Exogenous Hyperinsulinism | 1 | CTD_human |
| NEIL1 | C1257965 | Compensatory Hyperinsulinemia | 1 | CTD_human |
| NEIL1 | C1706412 | Lipidemias | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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