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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for CHMP6

check button Gene summary
Gene informationGene symbol

CHMP6

Gene ID

79643

Gene namecharged multivesicular body protein 6
SynonymsVPS20
Cytomap

17q25.3

Type of geneprotein-coding
Descriptioncharged multivesicular body protein 6chromatin-modifying protein 6hVps20vacuolar protein sorting-associated protein 20
Modification date20200313
UniProtAcc

Q96FZ7,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
CHMP6

GO:0039702

viral budding via host ESCRT complex

24878737


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RNA A-to-I events for CHMP6

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_672231(81001862, +), ADediting_672232(81001863, +), ADediting_672233(81001906, +), ADediting_672234(81001951, +), ADediting_672235(81001958, +), ADediting_672236(81001965, +), ADediting_672237(81001966, +), ADediting_672238(81001969, +), ADediting_672239(81001985, +), ADediting_672240(81001995, +), ADediting_672241(81002005, +), ADediting_672242(81002018, +), ADediting_672243(81002022, +), ADediting_672244(81002037, +), ADediting_672245(81002055, +), ADediting_672246(81002955, +), ADediting_672247(81002959, +), ADediting_672248(81002967, +), ADediting_672249(81002987, +), ADediting_672250(81003011, +), ADediting_672251(81003029, +), ADediting_672252(81003030, +), ADediting_672253(81003042, +), ADediting_672254(81003047, +), ADediting_672255(81003056, +), ADediting_672256(81003059, +), ADediting_672257(81003069, +), ADediting_672258(81003091, +), ADediting_672259(81003095, +), ADediting_672260(81003096, +), ADediting_672261(81003105, +), ADediting_672262(81003114, +), ADediting_672263(81003116, +), ADediting_672264(81003288, +), ADediting_672265(81003290, +), ADediting_672266(81003318, +), ADediting_672267(81003322, +), ADediting_672268(81003323, +), ADediting_672269(81003326, +), ADediting_672270(81003352, +), ADediting_672271(81003353, +), ADediting_672272(81003362, +), ADediting_672273(81003370, +), ADediting_672274(81003375, +), ADediting_672275(81003379, +), ADediting_672276(81003394, +), ADediting_672277(81003433, +), ADediting_672278(81005255, +), ADediting_672279(81005256, +), ADediting_672280(81005262, +), ADediting_672281(81005282, +), ADediting_672282(81005344, +), ADediting_672283(81005362, +), ADediting_672284(81005370, +), ADediting_672285(81005389, +), ADediting_672286(81005416, +), ADediting_672287(81005658, +), ADediting_672288(81005689, +), ADediting_672289(81005701, +), ADediting_672290(81005723, +), ADediting_672291(81005965, +), ADediting_672292(81006719, +), ADediting_672293(81006764, +), ADediting_672294(81006782, +), ADediting_672295(81006792, +), ADediting_672296(81007668, +), ADediting_672297(81007670, +), ADediting_672298(81007676, +), ADediting_672299(81007803, +), ADediting_672300(81007809, +), ADediting_672301(81007878, +), ADediting_672302(81007880, +), ADediting_672303(81007930, +), ADediting_672304(81007945, +), ADediting_672305(81007988, +), ADediting_672306(81008444, +), ADediting_672307(81008469, +), ADediting_672308(81008512, +), ADediting_672309(81008513, +), ADediting_672310(81008530, +), ADediting_672311(81008542, +), ADediting_672312(81008574, +), ADediting_672313(81008578, +), ADediting_672314(81008593, +), ADediting_672315(81008623, +), ADediting_672316(81008642, +), ADediting_672317(81008648, +), ADediting_672318(81008652, +), ADediting_672319(81008661, +), ADediting_672320(81008675, +), ADediting_672321(81008688, +), ADediting_672322(81008690, +), ADediting_672323(81009061, +), ADediting_672324(81009084, +), ADediting_672325(81009087, +), ADediting_1549808(81002061, +), ADediting_1549809(81002982, +), ADediting_1549810(81003085, +), ADediting_1549811(81003468, +), ADediting_1549812(81007836, +), ADediting_1549813(81007946, +), ADediting_1549814(81007950, +),

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RNA editing positional annotations for CHMP6 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_672231chr17_81001862_+intronic
ADediting_672232chr17_81001863_+intronic
ADediting_672233chr17_81001906_+intronic
ADediting_672234chr17_81001951_+intronic
ADediting_672235chr17_81001958_+intronic
ADediting_672236chr17_81001965_+intronic
ADediting_672237chr17_81001966_+intronic
ADediting_672238chr17_81001969_+intronic
ADediting_672239chr17_81001985_+intronic
ADediting_672240chr17_81001995_+intronic
ADediting_672241chr17_81002005_+intronic
ADediting_672242chr17_81002018_+intronic
ADediting_672243chr17_81002022_+intronic
ADediting_672244chr17_81002037_+intronic
ADediting_672245chr17_81002055_+intronic
ADediting_672246chr17_81002955_+intronic
ADediting_672247chr17_81002959_+intronic
ADediting_672248chr17_81002967_+intronic
ADediting_672249chr17_81002987_+intronic
ADediting_672250chr17_81003011_+intronic
ADediting_672251chr17_81003029_+intronic
ADediting_672252chr17_81003030_+intronic
ADediting_672253chr17_81003042_+intronic
ADediting_672254chr17_81003047_+intronic
ADediting_672255chr17_81003056_+intronic
ADediting_672256chr17_81003059_+intronic
ADediting_672257chr17_81003069_+intronic
ADediting_672258chr17_81003091_+intronic
ADediting_672259chr17_81003095_+intronic
ADediting_672260chr17_81003096_+intronic
ADediting_672261chr17_81003105_+intronic
ADediting_672262chr17_81003114_+intronic
ADediting_672263chr17_81003116_+intronic
ADediting_672264chr17_81003288_+intronic
ADediting_672265chr17_81003290_+intronic
ADediting_672266chr17_81003318_+intronic
ADediting_672267chr17_81003322_+intronic
ADediting_672268chr17_81003323_+intronic
ADediting_672269chr17_81003326_+intronic
ADediting_672270chr17_81003352_+ncRNA_exonic
ADediting_672271chr17_81003353_+ncRNA_exonic
ADediting_672272chr17_81003362_+ncRNA_exonic
ADediting_672273chr17_81003370_+ncRNA_exonic
ADediting_672274chr17_81003375_+ncRNA_exonic
ADediting_672275chr17_81003379_+ncRNA_exonic
ADediting_672276chr17_81003394_+ncRNA_exonic
ADediting_672277chr17_81003433_+ncRNA_exonic
ADediting_672278chr17_81005255_+intronic
ADediting_672279chr17_81005256_+intronic
ADediting_672280chr17_81005262_+intronic
ADediting_672281chr17_81005282_+intronic
ADediting_672282chr17_81005344_+intronic
ADediting_672283chr17_81005362_+intronic
ADediting_672284chr17_81005370_+intronic
ADediting_672285chr17_81005389_+intronic
ADediting_672286chr17_81005416_+intronic
ADediting_672287chr17_81005658_+intronic
ADediting_672288chr17_81005689_+intronic
ADediting_672289chr17_81005701_+intronic
ADediting_672290chr17_81005723_+intronic
ADediting_672291chr17_81005965_+intronic
ADediting_672292chr17_81006719_+intronic
ADediting_672293chr17_81006764_+intronic
ADediting_672294chr17_81006782_+intronic
ADediting_672295chr17_81006792_+intronic
ADediting_672296chr17_81007668_+intronic
ADediting_672297chr17_81007670_+intronic
ADediting_672298chr17_81007676_+intronic
ADediting_672299chr17_81007803_+intronic
ADediting_672300chr17_81007809_+intronic
ADediting_672301chr17_81007878_+intronic
ADediting_672302chr17_81007880_+intronic
ADediting_672303chr17_81007930_+intronic
ADediting_672304chr17_81007945_+intronic
ADediting_672305chr17_81007988_+intronic
ADediting_672306chr17_81008444_+intronic
ADediting_672307chr17_81008469_+intronic
ADediting_672308chr17_81008512_+intronic
ADediting_672309chr17_81008513_+intronic
ADediting_672310chr17_81008530_+intronic
ADediting_672311chr17_81008542_+intronic
ADediting_672312chr17_81008574_+intronic
ADediting_672313chr17_81008578_+intronic
ADediting_672314chr17_81008593_+intronic
ADediting_672315chr17_81008623_+intronic
ADediting_672316chr17_81008642_+intronic
ADediting_672317chr17_81008648_+intronic
ADediting_672318chr17_81008652_+intronic
ADediting_672319chr17_81008661_+intronic
ADediting_672320chr17_81008675_+intronic
ADediting_672321chr17_81008688_+intronic
ADediting_672322chr17_81008690_+intronic
ADediting_672323chr17_81009061_+intronic
ADediting_672324chr17_81009084_+intronic
ADediting_672325chr17_81009087_+intronic
ADediting_1549808chr17_81002061_+intronic
ADediting_1549809chr17_81002982_+intronic
ADediting_1549810chr17_81003085_+intronic
ADediting_1549811chr17_81003468_+ncRNA_exonic
ADediting_1549812chr17_81007836_+intronic
ADediting_1549813chr17_81007946_+intronic
ADediting_1549814chr17_81007950_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_672231chr17_81001862_+SINEAluName=AluSc
ADediting_672232chr17_81001863_+SINEAluName=AluSc
ADediting_672233chr17_81001906_+SINEAluName=AluSc
ADediting_672234chr17_81001951_+SINEAluName=AluSc
ADediting_672235chr17_81001958_+SINEAluName=AluSc
ADediting_672236chr17_81001965_+SINEAluName=AluSc
ADediting_672237chr17_81001966_+SINEAluName=AluSc
ADediting_672238chr17_81001969_+SINEAluName=AluSc
ADediting_672239chr17_81001985_+SINEAluName=AluSc
ADediting_672240chr17_81001995_+SINEAluName=AluSc
ADediting_672241chr17_81002005_+SINEAluName=AluSc
ADediting_672242chr17_81002018_+SINEAluName=AluSc
ADediting_672243chr17_81002022_+SINEAluName=AluSc
ADediting_672244chr17_81002037_+SINEAluName=AluSc
ADediting_672245chr17_81002055_+SINEAluName=AluSc
ADediting_672246chr17_81002955_+SINEAluName=AluJo
ADediting_672247chr17_81002959_+SINEAluName=AluJo
ADediting_672248chr17_81002967_+SINEAluName=AluJo
ADediting_672249chr17_81002987_+SINEAluName=AluJo
ADediting_672250chr17_81003011_+SINEAluName=AluJo
ADediting_672251chr17_81003029_+SINEAluName=AluJo
ADediting_672252chr17_81003030_+SINEAluName=AluJo
ADediting_672253chr17_81003042_+SINEAluName=AluJo
ADediting_672254chr17_81003047_+SINEAluName=AluJo
ADediting_672255chr17_81003056_+SINEAluName=AluJo
ADediting_672256chr17_81003059_+SINEAluName=AluJo
ADediting_672257chr17_81003069_+SINEAluName=AluJo
ADediting_672258chr17_81003091_+SINEAluName=AluJo
ADediting_672259chr17_81003095_+SINEAluName=AluJo
ADediting_672260chr17_81003096_+SINEAluName=AluJo
ADediting_672261chr17_81003105_+SINEAluName=AluJo
ADediting_672262chr17_81003114_+SINEAluName=AluJo
ADediting_672263chr17_81003116_+SINEAluName=AluJo
ADediting_672264chr17_81003288_+SINEAluName=AluSx
ADediting_672265chr17_81003290_+SINEAluName=AluSx
ADediting_672266chr17_81003318_+SINEAluName=AluSx
ADediting_672267chr17_81003322_+SINEAluName=AluSx
ADediting_672268chr17_81003323_+SINEAluName=AluSx
ADediting_672269chr17_81003326_+SINEAluName=AluSx
ADediting_672270chr17_81003352_+SINEAluName=AluSx
ADediting_672271chr17_81003353_+SINEAluName=AluSx
ADediting_672272chr17_81003362_+SINEAluName=AluSx
ADediting_672273chr17_81003370_+SINEAluName=AluSx
ADediting_672274chr17_81003375_+SINEAluName=AluSx
ADediting_672275chr17_81003379_+SINEAluName=AluSx
ADediting_672276chr17_81003394_+SINEAluName=AluSx
ADediting_672277chr17_81003433_+SINEAluName=AluSx
ADediting_672278chr17_81005255_+SINEAluName=AluSg
ADediting_672279chr17_81005256_+SINEAluName=AluSg
ADediting_672280chr17_81005262_+SINEAluName=AluSg
ADediting_672281chr17_81005282_+SINEAluName=AluSg
ADediting_672282chr17_81005344_+SINEAluName=AluSg
ADediting_672283chr17_81005362_+SINEAluName=AluSg
ADediting_672284chr17_81005370_+SINEAluName=AluSg
ADediting_672285chr17_81005389_+SINEAluName=AluSg
ADediting_672286chr17_81005416_+SINEAluName=AluSg
ADediting_672287chr17_81005658_+SINEAluName=AluSx
ADediting_672288chr17_81005689_+SINEAluName=AluSx
ADediting_672289chr17_81005701_+SINEAluName=AluSx
ADediting_672290chr17_81005723_+SINEAluName=AluSx
ADediting_672291chr17_81005965_+SINEAluName=AluSz
ADediting_672292chr17_81006719_+SINEAluName=AluSx
ADediting_672293chr17_81006764_+SINEAluName=AluSx
ADediting_672294chr17_81006782_+SINEAluName=AluSx
ADediting_672295chr17_81006792_+SINEAluName=AluSx
ADediting_672296chr17_81007668_+SINEAluName=AluY
ADediting_672297chr17_81007670_+SINEAluName=AluY
ADediting_672298chr17_81007676_+SINEAluName=AluY
ADediting_672299chr17_81007803_+SINEAluName=AluY
ADediting_672300chr17_81007809_+SINEAluName=AluY
ADediting_672301chr17_81007878_+SINEAluName=AluJr
ADediting_672302chr17_81007880_+SINEAluName=AluJr
ADediting_672303chr17_81007930_+SINEAluName=AluJr
ADediting_672304chr17_81007945_+SINEAluName=AluJr
ADediting_672305chr17_81007988_+SINEAluName=AluJr
ADediting_672306chr17_81008444_+SINEAluName=AluSz6
ADediting_672307chr17_81008469_+SINEAluName=AluSz6
ADediting_672308chr17_81008512_+SINEAluName=AluSz6
ADediting_672309chr17_81008513_+SINEAluName=AluSz6
ADediting_672310chr17_81008530_+SINEAluName=AluSz6
ADediting_672311chr17_81008542_+SINEAluName=AluSz6
ADediting_672312chr17_81008574_+SINEAluName=AluSz6
ADediting_672313chr17_81008578_+SINEAluName=AluSz6
ADediting_672314chr17_81008593_+SINEAluName=AluSz6
ADediting_672315chr17_81008623_+SINEAluName=AluSz6
ADediting_672316chr17_81008642_+SINEAluName=AluSz6
ADediting_672317chr17_81008648_+SINEAluName=AluSz6
ADediting_672318chr17_81008652_+SINEAluName=AluSz6
ADediting_672319chr17_81008661_+SINEAluName=AluSz6
ADediting_672320chr17_81008675_+SINEAluName=AluSz6
ADediting_672321chr17_81008688_+SINEAluName=AluSz6
ADediting_672322chr17_81008690_+SINEAluName=AluSz6
ADediting_672323chr17_81009061_+SINEAluName=AluSx
ADediting_672324chr17_81009084_+SINEAluName=AluSx
ADediting_672325chr17_81009087_+SINEAluName=AluSx
ADediting_1549808chr17_81002061_+SINEAluName=AluSc
ADediting_1549809chr17_81002982_+SINEAluName=AluJo
ADediting_1549810chr17_81003085_+SINEAluName=AluJo
ADediting_1549811chr17_81003468_+SINEAluName=AluSx
ADediting_1549812chr17_81007836_+SINEAluName=AluY
ADediting_1549813chr17_81007946_+SINEAluName=AluJr
ADediting_1549814chr17_81007950_+SINEAluName=AluJr

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RNA A-to-I editing events in the alternative splicing sites for CHMP6

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CHMP6

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for CHMP6

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CHMP6


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000176108.9ENST00000325167.9CHMP6-201hsa-miR-5688chr1780999871809998777mer-m88099985780999878145-10.69
ADediting_1337758chr7_5495892_-ENSG00000176108.9ENST00000325167.9CHMP6-201hsa-miR-589-5pchr1780999237809992437mer-m88099922380999244151-20.91
ADediting_98289chr1_32086992_+ENSG00000176108.9ENST00000572778.5CHMP6-204hsa-miR-5585-3pchr1780998636809986438mer-1a8099862180998643143-12.09

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CHMP6

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CHMP6

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_672240chr17_81001995_+1.61401558853669e-050.3441764422776620.002015734689097110.2501968359535280.5807350388086640.045452952552186
CERADediting_672241chr17_81002005_+3.19830026646261e-050.3326318907970259.0151560010106e-050.3142063992881050.4227860637096250.065930413257888
DLPFCADediting_672245chr17_81002055_+0.08293087921701380.09863867101672140.5648184673449840.03282130080930133.74318968489135e-090.326899635141635
DLPFCADediting_672248chr17_81002967_+7.24672497208293e-110.3590889078700042.95849855605908e-070.2861855013287814.22109674386659e-050.230376855935595
CERADediting_672252chr17_81003030_+1.23556821137703e-070.4155631409109512.5487218805526e-060.373244780185350.004817673605847070.229017216738065
CERADediting_672253chr17_81003042_+0.000118349208452450.3091625668219095.29885598912951e-050.3238034598068560.1514724603485490.117691293974981
CERADediting_672256chr17_81003059_+8.25007412436188e-060.3550782880860889.14729693989965e-060.353427260211590.9829964775575560.00175482624698189
CERADediting_672257chr17_81003069_+2.02776990790293e-060.3766562934087771.12542388563662e-060.3852670610223150.2105776545075310.102812577403771
CERADediting_672258chr17_81003091_+3.96837824747292e-050.3288925206534071.02752586973591e-060.3865763938530720.04124623594720560.166876290749771
CERADediting_672266chr17_81003318_+6.47317914043263e-050.3202263252354984.67396825523459e-050.3260231923931120.8187889027376960.0188623049537257
CERADediting_672269chr17_81003326_+1.9914137331744e-050.340678000788722.86776416658781e-050.3345044000748350.1720378265237970.112093675820892
DLPFCADediting_672271chr17_81003353_+2.3301418818069e-050.2377901514270220.01099756533619180.1442466486141889.27326625700358e-090.318939495515331
CERADediting_672274chr17_81003375_+0.003881537118053320.2344403278506640.0001711864512908290.3021732132968260.008571748428362140.213929585884473
CERADediting_672285chr17_81005389_+0.02770305882838210.1797856699826072.04394735039431e-050.3402415359783080.8682627206795170.0136564808813385
DLPFCADediting_672306chr17_81008444_+0.418149449592960.04614614809647840.952097338015749-0.003425757482584212.07501746172846e-120.385278576717148
DLPFCADediting_672307chr17_81008469_+0.8756358082851030.008924703512143520.340852020902091-0.05427678407603411.71053414740607e-080.313432958312244
DLPFCADediting_672309chr17_81008513_+0.903916392870605-0.006883906967842180.0985845597209168-0.09398528168704451.20617967975785e-120.389078705675448
DLPFCADediting_672316chr17_81008642_+0.1697639103314220.0781754718096690.747882507622395-0.01832866007136952.42921450723349e-130.400026683034236
DLPFCADediting_672319chr17_81008661_+0.2113400807430550.07118641192446640.79309648281369-0.01495676156852313.43069050375584e-090.327652551734535

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.00504189020715e-250.5482764368023411.73292910621012e-230.5263181419298361.63561220671683e-290.582126265035823
AC5.02533206218444e-680.8407336274596222.47576763430935e-440.7384369390975311.27955460937805e-190.531374703304591
PCC6.34466161857557e-340.7365353550855147.59429729716537e-280.6854543816714624.12701442378966e-060.326180234778644
TCX2.1256693827437e-140.5718147626215960.0001436267262356910.3055189051479980.0001690813078187830.302410375972577
FP3.5206670972436e-160.5615388403247561.86638370709135e-060.3485178631058081.95644917481362e-080.405551426675381
IFG1.25020777399401e-060.8045474575469333.94970120851257e-050.7262826770613040.09366592524259530.342579604863591
STG5.4598569315811e-100.6135610865361352.45330466339424e-050.4429235109837910.002371640328478940.327328076454075

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Relation with AD stages for CHMP6

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_672251chr17_81003029_+0.0003229584309121080.339646046243
CERADediting_672252chr17_81003030_+0.0002288426897349780.3475013160511
CERADediting_672257chr17_81003069_+0.0009798591851887970.312821758394619
TCXADediting_672253chr17_81003042_+0.001399796867166340.306429052488247

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for CHMP6

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CHMP6

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource