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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for ZXDC |
 Gene summary |
| Gene information | Gene symbol | ZXDC | Gene ID | 79364 |
| Gene name | ZXD family zinc finger C | |
| Synonyms | ZXDL | |
| Cytomap | 3q21.3 | |
| Type of gene | protein-coding | |
| Description | zinc finger protein ZXDCSERH2790ZXD-like zinc finger protein | |
| Modification date | 20200327 | |
| UniProtAcc | Q2QGD7, | |
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
| ZXDC | GO:0045893 | positive regulation of transcription, DNA-templated | 17696781 |
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RNA A-to-I events for ZXDC |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA editing frequencies across three data sets. |
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| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
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| RNA A-to-I editing events in AD. |
| ADediting_1019422(126444288, -), ADediting_1019423(126444289, -), ADediting_1019424(126444312, -), ADediting_1019425(126444365, -), ADediting_1019426(126444368, -), ADediting_1019427(126444410, -), ADediting_1019428(126444420, -), ADediting_1019429(126444469, -), ADediting_1019430(126452847, -), ADediting_1019431(126452934, -), ADediting_1019432(126452957, -), ADediting_1019433(126453010, -), ADediting_1019434(126453011, -), ADediting_1019435(126453791, -), ADediting_1019436(126453819, -), ADediting_1019437(126455732, -), ADediting_1019438(126455741, -), ADediting_1019439(126455753, -), ADediting_1019440(126455754, -), ADediting_1019441(126455804, -), ADediting_1019442(126455808, -), ADediting_1019443(126455811, -), ADediting_1019444(126455816, -), ADediting_1019445(126455831, -), ADediting_1019446(126455834, -), ADediting_1019447(126455840, -), ADediting_1019448(126455860, -), ADediting_1019449(126455878, -), ADediting_1019450(126455888, -), ADediting_1019451(126455900, -), ADediting_1019452(126455924, -), ADediting_1019453(126455937, -), ADediting_1019454(126455943, -), ADediting_1019455(126455953, -), ADediting_1019456(126455998, -), ADediting_1019457(126456331, -), ADediting_1019458(126458309, -), ADediting_1019459(126458322, -), ADediting_1019460(126458329, -), ADediting_1019461(126458342, -), ADediting_1019462(126458348, -), ADediting_1019463(126458365, -), ADediting_1019464(126458374, -), ADediting_1019465(126458375, -), ADediting_1019466(126458397, -), ADediting_1019467(126458401, -), ADediting_1019468(126458404, -), ADediting_1019469(126458405, -), ADediting_1019470(126458416, -), ADediting_1019471(126458417, -), ADediting_1019472(126458420, -), ADediting_1019473(126458431, -), ADediting_1019474(126458439, -), ADediting_1019475(126458441, -), ADediting_1019476(126458442, -), ADediting_1019477(126458465, -), ADediting_1019478(126458502, -), ADediting_1019479(126458505, -), ADediting_1019480(126458510, -), ADediting_1019481(126458511, -), ADediting_1019482(126458533, -), ADediting_1019483(126463207, -), ADediting_1019484(126463223, -), ADediting_1019485(126463233, -), ADediting_1019486(126463319, -), ADediting_1019487(126463341, -), ADediting_1019488(126463342, -), ADediting_1019489(126463348, -), ADediting_1019490(126465694, -), ADediting_1019491(126465706, -), ADediting_1019492(126465721, -), ADediting_1019493(126465779, -), ADediting_1019494(126465794, -), ADediting_1019495(126465802, -), ADediting_1019496(126465807, -), ADediting_1019497(126465813, -), ADediting_1019498(126465819, -), ADediting_1019499(126465827, -), ADediting_1019500(126465829, -), ADediting_1019501(126465834, -), ADediting_1019502(126465839, -), ADediting_1019503(126465899, -), ADediting_1019504(126465927, -), ADediting_1571998(126449334, -), ADediting_1571999(126458433, -), ADediting_1572000(126458451, -), ADediting_1644106(126453700, -), |
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RNA editing positional annotations for ZXDC using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_1019422 | chr3_126444288_- | intronic |
| ADediting_1019423 | chr3_126444289_- | intronic |
| ADediting_1019424 | chr3_126444312_- | intronic |
| ADediting_1019425 | chr3_126444365_- | intronic |
| ADediting_1019426 | chr3_126444368_- | intronic |
| ADediting_1019427 | chr3_126444410_- | intronic |
| ADediting_1019428 | chr3_126444420_- | intronic |
| ADediting_1019429 | chr3_126444469_- | intronic |
| ADediting_1019430 | chr3_126452847_- | intronic |
| ADediting_1019431 | chr3_126452934_- | intronic |
| ADediting_1019432 | chr3_126452957_- | intronic |
| ADediting_1019433 | chr3_126453010_- | intronic |
| ADediting_1019434 | chr3_126453011_- | intronic |
| ADediting_1019435 | chr3_126453791_- | intronic |
| ADediting_1019436 | chr3_126453819_- | intronic |
| ADediting_1019437 | chr3_126455732_- | intronic |
| ADediting_1019438 | chr3_126455741_- | intronic |
| ADediting_1019439 | chr3_126455753_- | intronic |
| ADediting_1019440 | chr3_126455754_- | intronic |
| ADediting_1019441 | chr3_126455804_- | intronic |
| ADediting_1019442 | chr3_126455808_- | intronic |
| ADediting_1019443 | chr3_126455811_- | intronic |
| ADediting_1019444 | chr3_126455816_- | intronic |
| ADediting_1019445 | chr3_126455831_- | intronic |
| ADediting_1019446 | chr3_126455834_- | intronic |
| ADediting_1019447 | chr3_126455840_- | intronic |
| ADediting_1019448 | chr3_126455860_- | intronic |
| ADediting_1019449 | chr3_126455878_- | intronic |
| ADediting_1019450 | chr3_126455888_- | intronic |
| ADediting_1019451 | chr3_126455900_- | intronic |
| ADediting_1019452 | chr3_126455924_- | intronic |
| ADediting_1019453 | chr3_126455937_- | intronic |
| ADediting_1019454 | chr3_126455943_- | intronic |
| ADediting_1019455 | chr3_126455953_- | intronic |
| ADediting_1019456 | chr3_126455998_- | intronic |
| ADediting_1019457 | chr3_126456331_- | intronic |
| ADediting_1019458 | chr3_126458309_- | intronic |
| ADediting_1019459 | chr3_126458322_- | intronic |
| ADediting_1019460 | chr3_126458329_- | intronic |
| ADediting_1019461 | chr3_126458342_- | intronic |
| ADediting_1019462 | chr3_126458348_- | intronic |
| ADediting_1019463 | chr3_126458365_- | intronic |
| ADediting_1019464 | chr3_126458374_- | intronic |
| ADediting_1019465 | chr3_126458375_- | intronic |
| ADediting_1019466 | chr3_126458397_- | intronic |
| ADediting_1019467 | chr3_126458401_- | intronic |
| ADediting_1019468 | chr3_126458404_- | intronic |
| ADediting_1019469 | chr3_126458405_- | intronic |
| ADediting_1019470 | chr3_126458416_- | intronic |
| ADediting_1019471 | chr3_126458417_- | intronic |
| ADediting_1019472 | chr3_126458420_- | intronic |
| ADediting_1019473 | chr3_126458431_- | intronic |
| ADediting_1019474 | chr3_126458439_- | intronic |
| ADediting_1019475 | chr3_126458441_- | intronic |
| ADediting_1019476 | chr3_126458442_- | intronic |
| ADediting_1019477 | chr3_126458465_- | intronic |
| ADediting_1019478 | chr3_126458502_- | intronic |
| ADediting_1019479 | chr3_126458505_- | intronic |
| ADediting_1019480 | chr3_126458510_- | intronic |
| ADediting_1019481 | chr3_126458511_- | intronic |
| ADediting_1019482 | chr3_126458533_- | intronic |
| ADediting_1019483 | chr3_126463207_- | intronic |
| ADediting_1019484 | chr3_126463223_- | intronic |
| ADediting_1019485 | chr3_126463233_- | intronic |
| ADediting_1019486 | chr3_126463319_- | intronic |
| ADediting_1019487 | chr3_126463341_- | intronic |
| ADediting_1019488 | chr3_126463342_- | intronic |
| ADediting_1019489 | chr3_126463348_- | intronic |
| ADediting_1019490 | chr3_126465694_- | intronic |
| ADediting_1019491 | chr3_126465706_- | intronic |
| ADediting_1019492 | chr3_126465721_- | intronic |
| ADediting_1019493 | chr3_126465779_- | intronic |
| ADediting_1019494 | chr3_126465794_- | intronic |
| ADediting_1019495 | chr3_126465802_- | intronic |
| ADediting_1019496 | chr3_126465807_- | intronic |
| ADediting_1019497 | chr3_126465813_- | intronic |
| ADediting_1019498 | chr3_126465819_- | intronic |
| ADediting_1019499 | chr3_126465827_- | intronic |
| ADediting_1019500 | chr3_126465829_- | intronic |
| ADediting_1019501 | chr3_126465834_- | intronic |
| ADediting_1019502 | chr3_126465839_- | intronic |
| ADediting_1019503 | chr3_126465899_- | intronic |
| ADediting_1019504 | chr3_126465927_- | intronic |
| ADediting_1571998 | chr3_126449334_- | intronic |
| ADediting_1571999 | chr3_126458433_- | intronic |
| ADediting_1572000 | chr3_126458451_- | intronic |
| ADediting_1644106 | chr3_126453700_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_1019422 | chr3_126444288_- | SINE | Alu | Name=AluY |
| ADediting_1019423 | chr3_126444289_- | SINE | Alu | Name=AluY |
| ADediting_1019424 | chr3_126444312_- | SINE | Alu | Name=AluY |
| ADediting_1019425 | chr3_126444365_- | SINE | Alu | Name=AluY |
| ADediting_1019426 | chr3_126444368_- | SINE | Alu | Name=AluY |
| ADediting_1019427 | chr3_126444410_- | SINE | Alu | Name=AluY |
| ADediting_1019428 | chr3_126444420_- | SINE | Alu | Name=AluY |
| ADediting_1019429 | chr3_126444469_- | SINE | Alu | Name=AluY |
| ADediting_1019430 | chr3_126452847_- | SINE | Alu | Name=AluJr |
| ADediting_1019431 | chr3_126452934_- | SINE | Alu | Name=AluJr |
| ADediting_1019432 | chr3_126452957_- | SINE | Alu | Name=AluJr |
| ADediting_1019433 | chr3_126453010_- | SINE | Alu | Name=AluJr |
| ADediting_1019434 | chr3_126453011_- | SINE | Alu | Name=AluJr |
| ADediting_1019435 | chr3_126453791_- | SINE | Alu | Name=AluSp |
| ADediting_1019436 | chr3_126453819_- | SINE | Alu | Name=AluSp |
| ADediting_1019437 | chr3_126455732_- | SINE | Alu | Name=AluY |
| ADediting_1019438 | chr3_126455741_- | SINE | Alu | Name=AluY |
| ADediting_1019439 | chr3_126455753_- | SINE | Alu | Name=AluY |
| ADediting_1019440 | chr3_126455754_- | SINE | Alu | Name=AluY |
| ADediting_1019441 | chr3_126455804_- | SINE | Alu | Name=AluY |
| ADediting_1019442 | chr3_126455808_- | SINE | Alu | Name=AluY |
| ADediting_1019443 | chr3_126455811_- | SINE | Alu | Name=AluY |
| ADediting_1019444 | chr3_126455816_- | SINE | Alu | Name=AluY |
| ADediting_1019445 | chr3_126455831_- | SINE | Alu | Name=AluY |
| ADediting_1019446 | chr3_126455834_- | SINE | Alu | Name=AluY |
| ADediting_1019447 | chr3_126455840_- | SINE | Alu | Name=AluY |
| ADediting_1019448 | chr3_126455860_- | SINE | Alu | Name=AluY |
| ADediting_1019449 | chr3_126455878_- | SINE | Alu | Name=AluY |
| ADediting_1019450 | chr3_126455888_- | SINE | Alu | Name=AluY |
| ADediting_1019451 | chr3_126455900_- | SINE | Alu | Name=AluY |
| ADediting_1019452 | chr3_126455924_- | SINE | Alu | Name=AluY |
| ADediting_1019453 | chr3_126455937_- | SINE | Alu | Name=AluY |
| ADediting_1019454 | chr3_126455943_- | SINE | Alu | Name=AluY |
| ADediting_1019455 | chr3_126455953_- | SINE | Alu | Name=AluY |
| ADediting_1019456 | chr3_126455998_- | SINE | Alu | Name=AluY |
| ADediting_1019457 | chr3_126456331_- | LTR | ERVL | Name=MER77 |
| ADediting_1019458 | chr3_126458309_- | SINE | Alu | Name=AluSx |
| ADediting_1019459 | chr3_126458322_- | SINE | Alu | Name=AluSx |
| ADediting_1019460 | chr3_126458329_- | SINE | Alu | Name=AluSx |
| ADediting_1019461 | chr3_126458342_- | SINE | Alu | Name=AluSx |
| ADediting_1019462 | chr3_126458348_- | SINE | Alu | Name=AluSx |
| ADediting_1019463 | chr3_126458365_- | SINE | Alu | Name=AluSx |
| ADediting_1019464 | chr3_126458374_- | SINE | Alu | Name=AluSx |
| ADediting_1019465 | chr3_126458375_- | SINE | Alu | Name=AluSx |
| ADediting_1019466 | chr3_126458397_- | SINE | Alu | Name=AluSx |
| ADediting_1019467 | chr3_126458401_- | SINE | Alu | Name=AluSx |
| ADediting_1019468 | chr3_126458404_- | SINE | Alu | Name=AluSx |
| ADediting_1019469 | chr3_126458405_- | SINE | Alu | Name=AluSx |
| ADediting_1019470 | chr3_126458416_- | SINE | Alu | Name=AluSx |
| ADediting_1019471 | chr3_126458417_- | SINE | Alu | Name=AluSx |
| ADediting_1019472 | chr3_126458420_- | SINE | Alu | Name=AluSx |
| ADediting_1019473 | chr3_126458431_- | SINE | Alu | Name=AluSx |
| ADediting_1019474 | chr3_126458439_- | SINE | Alu | Name=AluSx |
| ADediting_1019475 | chr3_126458441_- | SINE | Alu | Name=AluSx |
| ADediting_1019476 | chr3_126458442_- | SINE | Alu | Name=AluSx |
| ADediting_1019477 | chr3_126458465_- | SINE | Alu | Name=AluSx |
| ADediting_1019478 | chr3_126458502_- | SINE | Alu | Name=AluSx |
| ADediting_1019479 | chr3_126458505_- | SINE | Alu | Name=AluSx |
| ADediting_1019480 | chr3_126458510_- | SINE | Alu | Name=AluSx |
| ADediting_1019481 | chr3_126458511_- | SINE | Alu | Name=AluSx |
| ADediting_1019482 | chr3_126458533_- | SINE | Alu | Name=AluSx |
| ADediting_1019483 | chr3_126463207_- | SINE | Alu | Name=AluY |
| ADediting_1019484 | chr3_126463223_- | SINE | Alu | Name=AluY |
| ADediting_1019485 | chr3_126463233_- | SINE | Alu | Name=AluY |
| ADediting_1019486 | chr3_126463319_- | SINE | Alu | Name=AluY |
| ADediting_1019487 | chr3_126463341_- | SINE | Alu | Name=AluY |
| ADediting_1019488 | chr3_126463342_- | SINE | Alu | Name=AluY |
| ADediting_1019489 | chr3_126463348_- | SINE | Alu | Name=AluY |
| ADediting_1019490 | chr3_126465694_- | SINE | Alu | Name=AluJr |
| ADediting_1019491 | chr3_126465706_- | SINE | Alu | Name=AluJr |
| ADediting_1019492 | chr3_126465721_- | SINE | Alu | Name=AluJr |
| ADediting_1019493 | chr3_126465779_- | SINE | Alu | Name=AluJr |
| ADediting_1019494 | chr3_126465794_- | SINE | Alu | Name=AluJr |
| ADediting_1019495 | chr3_126465802_- | SINE | Alu | Name=AluJr |
| ADediting_1019496 | chr3_126465807_- | SINE | Alu | Name=AluJr |
| ADediting_1019497 | chr3_126465813_- | SINE | Alu | Name=AluJr |
| ADediting_1019498 | chr3_126465819_- | SINE | Alu | Name=AluJr |
| ADediting_1019499 | chr3_126465827_- | SINE | Alu | Name=AluJr |
| ADediting_1019500 | chr3_126465829_- | SINE | Alu | Name=AluJr |
| ADediting_1019501 | chr3_126465834_- | SINE | Alu | Name=AluJr |
| ADediting_1019502 | chr3_126465839_- | SINE | Alu | Name=AluJr |
| ADediting_1019503 | chr3_126465899_- | SINE | Alu | Name=AluJr |
| ADediting_1019504 | chr3_126465927_- | SINE | Alu | Name=AluJr |
| ADediting_1571998 | chr3_126449334_- | SINE | Alu | Name=FLAM_A |
| ADediting_1571999 | chr3_126458433_- | SINE | Alu | Name=AluSx |
| ADediting_1572000 | chr3_126458451_- | SINE | Alu | Name=AluSx |
| ADediting_1644106 | chr3_126453700_- | SINE | Alu | Name=AluSp |
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RNA A-to-I editing events in the alternative splicing sites for ZXDC |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZXDC |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
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Protein coding region RNA A-to-I editings for ZXDC |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for ZXDC |
| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_286380 | chr11_79422188_- | ENSG00000070476.15 | ENST00000336332.5 | ZXDC-201 | hsa-miR-5579-3p | chr3 | 126461160 | 126461166 | 7mer-m8 | 126461159 | 126461180 | 142 | -9.99 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1337757 | chr7_5495852_- | ENSG00000070476.15 | ENST00000389709.8 | ZXDC-202 | hsa-miR-589-3p | chr3 | 126437629 | 126437636 | 8mer-1a | 126437629 | 126437652 | 140 | -11.6 |
| ADediting_843620 | chr2_207754818_+ | ENSG00000070476.15 | ENST00000336332.5 | ZXDC-201 | hsa-miR-4775 | chr3 | 126461105 | 126461111 | 7mer-m8 | 126461104 | 126461125 | 140 | -5.24 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for ZXDC |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ZXDC |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1019438 | chr3_126455741_- | 0.00580290357335917 | 0.224248036100368 | 4.55615013007073e-06 | 0.364399311793021 | 0.478389901360179 | 0.0583195795788677 |
| CER | ADediting_1019441 | chr3_126455804_- | 4.79767247690376e-05 | 0.325562513578453 | 4.81926746728911e-08 | 0.42761759927238 | 0.117766547510214 | 0.128262666111401 |
| DLPFC | ADediting_1019442 | chr3_126455808_- | 2.5558151282056e-10 | 0.349196731008452 | 1.57802458812165e-06 | 0.268736810894352 | 1.12026358127425e-07 | 0.295788269161901 |
| CER | ADediting_1019442 | chr3_126455808_- | 1.06500145762462e-12 | 0.539400033735726 | 3.41377279014582e-18 | 0.633342217973405 | 0.00313018855521002 | 0.239724075745358 |
| TCX | ADediting_1019442 | chr3_126455808_- | 0.176675626337115 | 0.110900873606576 | 0.186743657170105 | -0.108388738482403 | 2.20998766621022e-08 | 0.437255585933956 |
| CER | ADediting_1019443 | chr3_126455811_- | 0.00137149641072968 | 0.259018707368267 | 3.69257623645638e-06 | 0.367629718965928 | 0.482684715223302 | 0.0577525952914708 |
| CER | ADediting_1019445 | chr3_126455831_- | 0.00122345486184894 | 0.261578397664205 | 2.90305459241944e-06 | 0.371285185229463 | 0.00588310001076181 | 0.223892472734171 |
| CER | ADediting_1019446 | chr3_126455834_- | 9.13391550021325e-07 | 0.388262074296519 | 2.03226556552238e-10 | 0.489648543298716 | 0.000287739123202864 | 0.292031786489768 |
| CER | ADediting_1019449 | chr3_126455878_- | 0.00149341412863665 | 0.257093644178587 | 5.72035301460305e-05 | 0.322440996439633 | 0.589541577305649 | 0.0443997200983863 |
| CER | ADediting_1019450 | chr3_126455888_- | 0.000318460241976873 | 0.290006222196655 | 2.88396728397209e-06 | 0.371384798904527 | 0.81109509097613 | 0.0196780996684288 |
| CER | ADediting_1019452 | chr3_126455924_- | 9.7262641803573e-09 | 0.447087899038098 | 3.41037537718015e-11 | 0.507476687884311 | 4.03218999699235e-05 | 0.328614085741502 |
| CER | ADediting_1019453 | chr3_126455937_- | 8.46778251988128e-07 | 0.389341269341 | 6.6357396775744e-10 | 0.47723702620204 | 0.0055876918528793 | 0.225224352203085 |
| DLPFC | ADediting_1019456 | chr3_126455998_- | 0.339085069856595 | 0.0544754488149538 | 0.33679508328097 | -0.0547339063904391 | 1.84909063639835e-08 | 0.31272434577385 |
| CER | ADediting_1019458 | chr3_126458309_- | 7.10352804921113e-05 | 0.318550382606225 | 3.49585189360934e-08 | 0.431622829908664 | 0.0178947193912253 | 0.19312112022994 |
| CER | ADediting_1019459 | chr3_126458322_- | 7.88714019520962e-12 | 0.52136874729235 | 7.65798962400341e-15 | 0.579719852105305 | 5.01027228108872e-05 | 0.324796216167949 |
| CER | ADediting_1019460 | chr3_126458329_- | 5.11596586329326e-09 | 0.454572845396608 | 1.04564762085597e-12 | 0.5395603536941 | 0.00765209982366231 | 0.216977973099713 |
| CER | ADediting_1019462 | chr3_126458348_- | 0.000275289044720429 | 0.292910321797313 | 3.5410997462695e-06 | 0.368269436773562 | 0.161584121579784 | 0.114872475278569 |
| CER | ADediting_1019463 | chr3_126458365_- | 0.00201162922203162 | 0.250244353479339 | 7.94858177248342e-05 | 0.316509836310007 | 0.0119801621845601 | 0.20469853561877 |
| CER | ADediting_1019464 | chr3_126458374_- | 1.34234261058089e-11 | 0.516395660119488 | 1.53328737537009e-12 | 0.536196552005414 | 0.002384505611571 | 0.246250186693899 |
| CER | ADediting_1019476 | chr3_126458442_- | 6.79838331313988e-06 | 0.358148857593511 | 9.59946863409425e-09 | 0.447242595819323 | 0.51708054495988 | 0.0533052075240461 |
| CER | ADediting_1572000 | chr3_126458451_- | 0.00654800754002014 | 0.221100356439404 | 2.33042405911965e-05 | 0.338032830218752 | 0.0514959717450814 | 0.159314005807862 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 1.06761836919607e-27 | 0.566396576836861 | 3.97260383256956e-25 | 0.54257185348827 | 2.35101214266066e-13 | 0.400246085220733 |
| AC | 1.29802557303187e-28 | 0.626060853947187 | 1.4455220903666e-20 | 0.542908906288894 | 1.15367501320678e-21 | 0.555748252046496 |
| PCC | 7.10773418267215e-09 | 0.403532538021132 | 1.55460731598804e-06 | 0.33946190059843 | 6.67574288613393e-11 | 0.449797419108839 |
| CER | 2.32795984830574e-60 | 0.915398733927328 | 1.44436783672995e-33 | 0.792289081077652 | 9.85261995732917e-05 | 0.312569981523015 |
| TCX | 5.7639263179776e-13 | 0.544721332060444 | 0.450898371689352 | 0.0620166713093444 | 3.16060941900297e-26 | 0.729869407996854 |
| FP | 1.24567873217658e-25 | 0.681314823289411 | 2.03241640187751e-13 | 0.514518117700237 | 1.24271218492329e-22 | 0.648665189254312 |
| IFG | 3.68647095054709e-05 | 0.72816219016921 | 9.99394187136092e-05 | 0.699435623860984 | 0.000276015631393052 | 0.666366079228821 |
| PG | 1.1261081686988e-13 | 0.509414483200051 | 3.62042045270929e-09 | 0.415717373430325 | 1.94032773425968e-10 | 0.44514372802554 |
| STG | 8.46695616068876e-11 | 0.635365484393341 | 0.00125297859141686 | 0.346273733349928 | 1.19827634063405e-08 | 0.573334510450048 |
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Relation with AD stages for ZXDC |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_1019442 | chr3_126455808_- | 2.5448245939596e-05 | 0.393305295624831 |
| CER | ADediting_1019446 | chr3_126455834_- | 0.000640613702881637 | 0.323384016497258 |
| CER | ADediting_1019452 | chr3_126455924_- | 0.000569352069732606 | 0.326248596165199 |
| CER | ADediting_1019458 | chr3_126458309_- | 0.00129777660694829 | 0.305620856771096 |
| CER | ADediting_1019459 | chr3_126458322_- | 0.000918089249946363 | 0.314465116408059 |
| CER | ADediting_1019460 | chr3_126458329_- | 0.000777346989762881 | 0.318623218697818 |
| CER | ADediting_1019463 | chr3_126458365_- | 0.00046214054442353 | 0.331249186125553 |
| CER | ADediting_1019464 | chr3_126458374_- | 0.00150448082075692 | 0.301759901431029 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
| CER | 9.78010887342269e-06 | 0.411302066630302 |
| TCX | 4.65251321530653e-10 | 0.559199838712823 |
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RelatedDrugs for ZXDC |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZXDC |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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