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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for UQCC3

check button Gene summary
Gene informationGene symbol

UQCC3

Gene ID

790955

Gene nameubiquinol-cytochrome c reductase complex assembly factor 3
SynonymsC11orf83|CCDS41658.1|MC3DN9|UNQ655
Cytomap

11q12.3

Type of geneprotein-coding
Descriptionubiquinol-cytochrome-c reductase complex assembly factor 3UPF0723 protein C11orf83assembly factor CBP4 homolog
Modification date20200313
UniProtAcc

Q6UW78,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for UQCC3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_262216(62672566, +), ADediting_262217(62672585, +), ADediting_262218(62672604, +), ADediting_262219(62672607, +), ADediting_262220(62672608, +), ADediting_262221(62672633, +), ADediting_262222(62672643, +), ADediting_262223(62672646, +), ADediting_262224(62672660, +), ADediting_262225(62672684, +), ADediting_262226(62672693, +), ADediting_262227(62672703, +), ADediting_262228(62672712, +), ADediting_262229(62672776, +), ADediting_262230(62672873, +), ADediting_262231(62672934, +), ADediting_262232(62672948, +), ADediting_262233(62672989, +), ADediting_262234(62672992, +), ADediting_262235(62673016, +), ADediting_262236(62673081, +), ADediting_1527354(62672859, +), ADediting_1527355(62672888, +), ADediting_1527356(62673041, +),

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RNA editing positional annotations for UQCC3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_262216chr11_62672566_+UTR3
ADediting_262217chr11_62672585_+UTR3
ADediting_262218chr11_62672604_+UTR3
ADediting_262219chr11_62672607_+UTR3
ADediting_262220chr11_62672608_+UTR3
ADediting_262221chr11_62672633_+UTR3
ADediting_262222chr11_62672643_+UTR3
ADediting_262223chr11_62672646_+UTR3
ADediting_262224chr11_62672660_+UTR3
ADediting_262225chr11_62672684_+UTR3
ADediting_262226chr11_62672693_+UTR3
ADediting_262227chr11_62672703_+UTR3
ADediting_262228chr11_62672712_+UTR3
ADediting_262229chr11_62672776_+UTR3
ADediting_262230chr11_62672873_+UTR3
ADediting_262231chr11_62672934_+UTR3
ADediting_262232chr11_62672948_+UTR3
ADediting_262233chr11_62672989_+UTR3
ADediting_262234chr11_62672992_+UTR3
ADediting_262235chr11_62673016_+UTR3
ADediting_262236chr11_62673081_+UTR3
ADediting_1527354chr11_62672859_+UTR3
ADediting_1527355chr11_62672888_+UTR3
ADediting_1527356chr11_62673041_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_262216chr11_62672566_+SINEAluName=AluSx
ADediting_262217chr11_62672585_+SINEAluName=AluSx
ADediting_262218chr11_62672604_+SINEAluName=AluSx
ADediting_262219chr11_62672607_+SINEAluName=AluSx
ADediting_262220chr11_62672608_+SINEAluName=AluSx
ADediting_262221chr11_62672633_+SINEAluName=AluSx
ADediting_262222chr11_62672643_+SINEAluName=AluSx
ADediting_262223chr11_62672646_+SINEAluName=AluSx
ADediting_262224chr11_62672660_+SINEAluName=AluSx
ADediting_262225chr11_62672684_+SINEAluName=AluSx
ADediting_262226chr11_62672693_+SINEAluName=AluSx
ADediting_262227chr11_62672703_+SINEAluName=AluSx
ADediting_262228chr11_62672712_+SINEAluName=AluSx
ADediting_262229chr11_62672776_+SINEAluName=AluSx
ADediting_262230chr11_62672873_+SINEAluName=AluSq2
ADediting_262231chr11_62672934_+SINEAluName=AluSq2
ADediting_262232chr11_62672948_+SINEAluName=AluSq2
ADediting_262233chr11_62672989_+SINEAluName=AluSq2
ADediting_262234chr11_62672992_+SINEAluName=AluSq2
ADediting_262235chr11_62673016_+SINEAluName=AluSq2
ADediting_262236chr11_62673081_+SINEAluName=AluSq2
ADediting_1527354chr11_62672859_+SINEAluName=AluSq2
ADediting_1527355chr11_62672888_+SINEAluName=AluSq2
ADediting_1527356chr11_62673041_+SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for UQCC3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for UQCC3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
Soverview
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Soverview
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for UQCC3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for UQCC3

check buttonRNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
all structure

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6752-3pchr1162672852626728587mer-m86267283962672859140-16.67
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6801-3pchr1162672853626728597mer-m86267284162672860145-21.78
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6810-3pchr1162672853626728597mer-m86267283862672860141-16.36
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6752-3pchr1162672852626728587mer-m86267283962672859140-16.67
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6801-3pchr1162672853626728597mer-m86267284162672860145-21.78
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6810-3pchr1162672853626728597mer-m86267283862672860141-16.36
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-17-3pchr1162672578626725847mer-m86267256462672585150-17.84
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-485-5pchr1162672582626725887mer-m86267256962672589153-19.07
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6884-5pchr1162672582626725887mer-m86267256662672589150-23.9
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-17-3pchr1162672578626725847mer-m86267256462672585150-17.84
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-485-5pchr1162672582626725887mer-m86267256962672589153-19.07
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6884-5pchr1162672582626725887mer-m86267256662672589150-23.9
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-146a-5pchr1162672606626726127mer-m86267258962672613155-23.99
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-146b-5pchr1162672606626726127mer-m86267258862672613152-21.86
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-7153-5pchr1162672606626726127mer-m86267259162672613145-17.33
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-146a-5pchr1162672606626726127mer-m86267258962672613155-23.99
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-146b-5pchr1162672606626726127mer-m86267258862672613152-21.86
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-7153-5pchr1162672606626726127mer-m86267259162672613145-17.33
ADediting_262223chr11_62672646_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-4679chr1162672639626726457mer-m86267262562672646148-16.79
ADediting_262223chr11_62672646_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6804-3pchr1162672643626726497mer-m86267262862672650147-21.04
ADediting_262223chr11_62672646_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-4679chr1162672639626726457mer-m86267262562672646148-16.79
ADediting_262223chr11_62672646_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6804-3pchr1162672643626726497mer-m86267262862672650147-21.04
ADediting_262224chr11_62672660_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-2861chr1162672657626726648mer-1a6267264662672664165-33.72
ADediting_262224chr11_62672660_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-2861chr1162672657626726648mer-1a6267264662672664165-33.72
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-340-3pchr1162672687626726937mer-m86267267362672694157-22.73
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6827-3pchr1162672687626726937mer-m86267267462672694145-16.39
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-340-3pchr1162672687626726937mer-m86267267362672694157-22.73
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6827-3pchr1162672687626726937mer-m86267267462672694145-16.39
ADediting_262227chr11_62672703_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-433-5pchr1162672697626727037mer-m86267268362672704164-26.92
ADediting_262227chr11_62672703_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-433-5pchr1162672697626727037mer-m86267268362672704164-26.92
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-455-3pchr1162672710626727167mer-m86267269662672717146-15.25
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6512-3pchr1162672707626727137mer-m86267269662672714143-17.99
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6720-5pchr1162672707626727137mer-m86267268962672714151-21.3
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-455-3pchr1162672710626727167mer-m86267269662672717146-15.25
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6512-3pchr1162672707626727137mer-m86267269662672714143-17.99
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6720-5pchr1162672707626727137mer-m86267268962672714151-21.3
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-602chr1162672930626729378mer-1a6267291462672937147-19.42
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-602chr1162672930626729378mer-1a6267291462672937147-19.42
ADediting_262233chr11_62672989_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1323chr1162672982626729887mer-m86267296862672989141-11.25
ADediting_262233chr11_62672989_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-548o-3pchr1162672982626729887mer-m86267296862672989151-15.73
ADediting_262233chr11_62672989_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1323chr1162672982626729887mer-m86267296862672989141-11.25
ADediting_262233chr11_62672989_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-548o-3pchr1162672982626729887mer-m86267296862672989151-15.73
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-3940-3pchr1162673013626730197mer-m86267300062673020144-22.21
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-3940-3pchr1162673013626730197mer-m86267300062673020144-22.21

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1976chr1162672853626728597mer-m86267284162672860145-15.67
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-483-3pchr1162672855626728617mer-m86267284262672862143-14.73
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1976chr1162672853626728597mer-m86267284162672860145-15.67
ADediting_1527354chr11_62672859_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-483-3pchr1162672855626728617mer-m86267284262672862143-14.73
ADediting_1527355chr11_62672888_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-377-5pchr1162672886626728927mer-m86267287262672893155-19.35
ADediting_1527355chr11_62672888_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6086chr1162672886626728927mer-m86267287462672893148-19
ADediting_1527355chr11_62672888_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6516-5pchr1162672882626728887mer-m86267286662672889151-16.01
ADediting_1527355chr11_62672888_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-377-5pchr1162672886626728927mer-m86267287262672893155-19.35
ADediting_1527355chr11_62672888_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6086chr1162672886626728927mer-m86267287462672893148-19
ADediting_1527355chr11_62672888_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6516-5pchr1162672882626728887mer-m86267286662672889151-16.01
ADediting_1527356chr11_62673041_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-7162-3pchr1162673035626730417mer-m86267302262673042142-17.47
ADediting_1527356chr11_62673041_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-7162-3pchr1162673035626730417mer-m86267302262673042142-17.47
ADediting_262216chr11_62672566_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1227-3pchr1162672560626725667mer-m86267254862672567148-22.88
ADediting_262216chr11_62672566_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1227-3pchr1162672560626725667mer-m86267254862672567148-22.88
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-377-5pchr1162672582626725887mer-m86267256662672589150-17.59
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6086chr1162672582626725887mer-m86267257062672589150-23.99
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6516-5pchr1162672578626725847mer-m86267256062672585147-15.44
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-377-5pchr1162672582626725887mer-m86267256662672589150-17.59
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6086chr1162672582626725887mer-m86267257062672589150-23.99
ADediting_262217chr11_62672585_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6516-5pchr1162672578626725847mer-m86267256062672585147-15.44
ADediting_262219chr11_62672607_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-219b-3pchr1162672604626726107mer-m86267259362672611147-18.48
ADediting_262219chr11_62672607_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-302fchr1162672603626726097mer-m86267259462672610140-8.67
ADediting_262219chr11_62672607_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-219b-3pchr1162672604626726107mer-m86267259362672611147-18.48
ADediting_262219chr11_62672607_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-302fchr1162672603626726097mer-m86267259462672610140-8.67
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-219b-3pchr1162672604626726107mer-m86267259362672611147-18.48
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-302fchr1162672603626726097mer-m86267259462672610140-8.67
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-219b-3pchr1162672604626726107mer-m86267259362672611147-18.48
ADediting_262220chr11_62672608_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-302fchr1162672603626726097mer-m86267259462672610140-8.67
ADediting_262222chr11_62672643_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-8070chr1162672639626726457mer-1a6267262662672645148-22.38
ADediting_262222chr11_62672643_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-8070chr1162672639626726457mer-1a6267262662672645148-22.38
ADediting_262223chr11_62672646_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6500-3pchr1162672642626726487mer-m86267262962672649140-16.12
ADediting_262223chr11_62672646_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6500-3pchr1162672642626726487mer-m86267262962672649140-16.12
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-10a-5pchr1162672690626726967mer-m86267267562672697140-13.09
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-10b-5pchr1162672690626726967mer-m86267267462672697148-14.27
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-339-5pchr1162672689626726957mer-m86267267262672696152-20.07
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-4421chr1162672688626726947mer-m86267267462672695146-13.85
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-5699-3pchr1162672688626726947mer-m86267267462672695145-17.39
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6732-3pchr1162672691626726977mer-m86267267762672698151-16.76
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-10a-5pchr1162672690626726967mer-m86267267562672697140-13.09
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-10b-5pchr1162672690626726967mer-m86267267462672697148-14.27
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-339-5pchr1162672689626726957mer-m86267267262672696152-20.07
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-4421chr1162672688626726947mer-m86267267462672695146-13.85
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-5699-3pchr1162672688626726947mer-m86267267462672695145-17.39
ADediting_262226chr11_62672693_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6732-3pchr1162672691626726977mer-m86267267762672698151-16.76
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1287-3pchr1162672707626727137mer-m86267269662672714155-16.8
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-4662a-5pchr1162672705626727117mer-m86267268962672712150-15.5
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1287-3pchr1162672707626727137mer-m86267269662672714155-16.8
ADediting_262228chr11_62672712_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-4662a-5pchr1162672705626727117mer-m86267268962672712150-15.5
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1273h-5pchr1162672927626729337mer-m86267291462672934145-16.89
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-30b-3pchr1162672927626729337mer-m86267291462672934149-15.87
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-3689a-3pchr1162672927626729337mer-m86267291362672934149-17.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-3689b-3pchr1162672927626729337mer-m86267291362672934149-17.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-3689cchr1162672927626729337mer-m86267291362672934149-17.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6779-5pchr1162672927626729337mer-m86267291662672934153-25.96
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6780a-5pchr1162672927626729337mer-m86267290362672934146-25.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-6871-5pchr1162672928626729347mer-m86267291562672935148-21.31
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1273h-5pchr1162672927626729337mer-m86267291462672934145-16.89
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-30b-3pchr1162672927626729337mer-m86267291462672934149-15.87
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-3689a-3pchr1162672927626729337mer-m86267291362672934149-17.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-3689b-3pchr1162672927626729337mer-m86267291362672934149-17.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-3689cchr1162672927626729337mer-m86267291362672934149-17.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6779-5pchr1162672927626729337mer-m86267291662672934153-25.96
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6780a-5pchr1162672927626729337mer-m86267290362672934146-25.29
ADediting_262231chr11_62672934_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-6871-5pchr1162672928626729347mer-m86267291562672935148-21.31
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-3190-5pchr1162673010626730167mer-m86267299862673017140-15.36
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-4701-5pchr1162673009626730157mer-m86267299562673016140-19.8
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-588chr1162673009626730157mer-m86267299862673016155-22.26
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-3190-5pchr1162673010626730167mer-m86267299862673017140-15.36
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-4701-5pchr1162673009626730157mer-m86267299562673016140-19.8
ADediting_262235chr11_62673016_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-588chr1162673009626730157mer-m86267299862673016155-22.26

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337758chr7_5495892_-ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-589-5pchr1162673602626736098mer-1a6267358862673609151-20.84
ADediting_527135chr16_24203190_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1273h-3pchr1162672296626723038mer-1a6267228062672303143-15.65
ADediting_527135chr16_24203190_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-1273h-3pchr1162672953626729608mer-1a6267293762672960155-25.04
ADediting_527135chr16_24203190_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1273h-3pchr1162672296626723038mer-1a6267228062672303143-15.65
ADediting_527135chr16_24203190_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-1273h-3pchr1162672953626729608mer-1a6267293762672960155-25.04
ADediting_843620chr2_207754818_+ENSG00000204922.5ENST00000377953.4UQCC3-201hsa-miR-4775chr1162672356626723627mer-m86267234162672363167-11.79
ADediting_843620chr2_207754818_+ENSG00000204922.5ENST00000531323.1UQCC3-202hsa-miR-4775chr1162672356626723627mer-m86267234162672363167-11.79

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for UQCC3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000531323.1protein_codingSoverviewSoverview
ENST00000377953.4protein_codingSoverviewSoverview

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
ADediting_262216ENST00000531323.1chr11_62672566_+1277-901.40-901.40-935.40
ADediting_262217ENST00000531323.1chr11_62672585_+1296-901.40-901.40-935.40
ADediting_262218ENST00000531323.1chr11_62672604_+1315-901.40-901.40-935.40
ADediting_262219ENST00000531323.1chr11_62672607_+1318-901.10-901.40-935.40
ADediting_262220ENST00000531323.1chr11_62672608_+1319-902.40-901.40-935.40
ADediting_262221ENST00000531323.1chr11_62672633_+1344-901.40-901.40-935.40
ADediting_262222ENST00000531323.1chr11_62672643_+1354-901.00-901.40-935.40
ADediting_262223ENST00000531323.1chr11_62672646_+1357-905.10-901.40-935.40
ADediting_262224ENST00000531323.1chr11_62672660_+1371-905.00-901.40-935.40
ADediting_262225ENST00000531323.1chr11_62672684_+1395-902.80-901.40-935.40
ADediting_262226ENST00000531323.1chr11_62672693_+1404-902.30-901.40-935.40
ADediting_262227ENST00000531323.1chr11_62672703_+1414-902.20-901.40-935.40
ADediting_262228ENST00000531323.1chr11_62672712_+1423-903.40-901.40-935.40
ADediting_262229ENST00000531323.1chr11_62672776_+1487-904.50-901.40-935.40
ADediting_1527354ENST00000531323.1chr11_62672859_+1570-907.90-901.40-935.40
ADediting_262230ENST00000531323.1chr11_62672873_+1584-901.40-901.40-935.40
ADediting_1527355ENST00000531323.1chr11_62672888_+1599-901.30-901.40-935.40
ADediting_262231ENST00000531323.1chr11_62672934_+1645-900.70-901.40-935.40
ADediting_262232ENST00000531323.1chr11_62672948_+1659-901.40-901.40-935.40
ADediting_262233ENST00000531323.1chr11_62672989_+1700-901.00-901.40-935.40
ADediting_262234ENST00000531323.1chr11_62672992_+1703-901.10-901.40-935.40
ADediting_262235ENST00000531323.1chr11_62673016_+1727-900.70-901.40-935.40
ADediting_1527356ENST00000531323.1chr11_62673041_+1752-900.70-901.40-935.40
ADediting_262236ENST00000531323.1chr11_62673081_+1792-905.30-901.40-935.40
ADediting_262216ENST00000377953.4chr11_62672566_+807-754.80-754.80-792.40
ADediting_262217ENST00000377953.4chr11_62672585_+826-754.80-754.80-792.40
ADediting_262218ENST00000377953.4chr11_62672604_+845-755.70-754.80-792.40
ADediting_262219ENST00000377953.4chr11_62672607_+848-754.50-754.80-792.40
ADediting_262220ENST00000377953.4chr11_62672608_+849-755.80-754.80-792.40
ADediting_262221ENST00000377953.4chr11_62672633_+874-758.20-754.80-792.40
ADediting_262222ENST00000377953.4chr11_62672643_+884-757.60-754.80-792.40
ADediting_262223ENST00000377953.4chr11_62672646_+887-758.50-754.80-792.40
ADediting_262224ENST00000377953.4chr11_62672660_+901-758.40-754.80-792.40
ADediting_262225ENST00000377953.4chr11_62672684_+925-757.10-754.80-792.40
ADediting_262226ENST00000377953.4chr11_62672693_+934-756.60-754.80-792.40
ADediting_262227ENST00000377953.4chr11_62672703_+944-755.60-754.80-792.40
ADediting_262228ENST00000377953.4chr11_62672712_+953-756.80-754.80-792.40
ADediting_262229ENST00000377953.4chr11_62672776_+1017-757.90-754.80-792.40
ADediting_1527354ENST00000377953.4chr11_62672859_+1100-761.30-754.80-792.40
ADediting_262230ENST00000377953.4chr11_62672873_+1114-754.80-754.80-792.40
ADediting_1527355ENST00000377953.4chr11_62672888_+1129-754.70-754.80-792.40
ADediting_262231ENST00000377953.4chr11_62672934_+1175-754.10-754.80-792.40
ADediting_262232ENST00000377953.4chr11_62672948_+1189-754.80-754.80-792.40
ADediting_262233ENST00000377953.4chr11_62672989_+1230-754.40-754.80-792.40
ADediting_262234ENST00000377953.4chr11_62672992_+1233-754.50-754.80-792.40
ADediting_262235ENST00000377953.4chr11_62673016_+1257-758.00-754.80-792.40
ADediting_1527356ENST00000377953.4chr11_62673041_+1282-754.10-754.80-792.40
ADediting_262236ENST00000377953.4chr11_62673081_+1322-759.60-754.80-792.40

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for UQCC3

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_262216chr11_62672566_+0.03477592776804920.1199457359567490.149335822668370.08208670999573326.74129899400785e-130.393100356557238
DLPFCADediting_262219chr11_62672607_+0.91490381519943-0.006093530438946130.59518070069078-0.03029374032247485.23726678756806e-080.303068530193637
DLPFCADediting_262222chr11_62672643_+0.4395554567334230.04405693451299440.880800541064913-0.008551230464252776.57031569296582e-080.300918227335801
DLPFCADediting_262223chr11_62672646_+0.4367160624285620.04433062958000510.564037848293908-0.03288711777860789.52099481896514e-100.338493734997705
DLPFCADediting_262236chr11_62673081_+0.7398640139602890.01893302606649360.512121317205679-0.03737002470826891.93547326697621e-090.332545997755254

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.46794450231876e-120.3877085960440133.89837369602234e-070.2833912255891481.37131033962224e-620.772066330068285
AC7.19659658664699e-390.7049272378818341.68043490757548e-280.6250539757717053.86969471103943e-220.561129213352973
PCC2.48816120439241e-170.5625112791996022.97266283177163e-200.6024604557962340.0006898369007523090.243444604387763
CER0.01874086102373270.1917489997699671.28959664745041e-080.4437436192056960.0004281613104946370.284008143844738
TCX3.33534632604568e-060.3691812897377633.02208380097964e-050.33360621246170.02354633514489330.184841809196453
FP7.81995376708615e-120.4838419707234217.49696430497128e-160.5563187512696240.001686807384823630.233764529347444
IFG2.04381759496151e-050.7436374987871121.34802884112016e-060.8031355141840650.6483514642992130.0959101865289809
STG3.93428084484183e-080.5562713210308362.67352232309188e-060.4867176113798740.09265352305629270.184659037010413

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Relation with AD stages for UQCC3

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_262218chr11_62672604_+0.001319780788894690.305184245033432

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.001245122414606120.30669361573539

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RelatedDrugs for UQCC3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for UQCC3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
UQCC3C4015253MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 91UNIPROT