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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited versus non-edited samples

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Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

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The effects of the RNA editing to the stability of the RNA structures

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Relation with ADAR

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Relation with AD stages

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Related drugs with this gene

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Related diseases with this gene


Gene summary for UQCC3

check button Gene summary
Gene informationGene symbol

UQCC3

Gene ID

790955

Gene nameubiquinol-cytochrome c reductase complex assembly factor 3
SynonymsC11orf83|CCDS41658.1|MC3DN9|UNQ655
Cytomap

11q12.3

Type of geneprotein-coding
Descriptionubiquinol-cytochrome-c reductase complex assembly factor 3UPF0723 protein C11orf83assembly factor CBP4 homolog
Modification date20200313
UniProtAcc

Q6UW78,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for UQCC3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_262216(62672566, +), ADediting_262217(62672585, +), ADediting_262218(62672604, +), ADediting_262219(62672607, +), ADediting_262220(62672608, +), ADediting_262221(62672633, +), ADediting_262222(62672643, +), ADediting_262223(62672646, +), ADediting_262224(62672660, +), ADediting_262225(62672684, +), ADediting_262226(62672693, +), ADediting_262227(62672703, +), ADediting_262228(62672712, +), ADediting_262229(62672776, +), ADediting_262230(62672873, +), ADediting_262231(62672934, +), ADediting_262232(62672948, +), ADediting_262233(62672989, +), ADediting_262234(62672992, +), ADediting_262235(62673016, +), ADediting_262236(62673081, +), ADediting_1527354(62672859, +), ADediting_1527355(62672888, +), ADediting_1527356(62673041, +),

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RNA editing positional annotations for UQCC3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_262216chr11_62672566_+UTR3
ADediting_262217chr11_62672585_+UTR3
ADediting_262218chr11_62672604_+UTR3
ADediting_262219chr11_62672607_+UTR3
ADediting_262220chr11_62672608_+UTR3
ADediting_262221chr11_62672633_+UTR3
ADediting_262222chr11_62672643_+UTR3
ADediting_262223chr11_62672646_+UTR3
ADediting_262224chr11_62672660_+UTR3
ADediting_262225chr11_62672684_+UTR3
ADediting_262226chr11_62672693_+UTR3
ADediting_262227chr11_62672703_+UTR3
ADediting_262228chr11_62672712_+UTR3
ADediting_262229chr11_62672776_+UTR3
ADediting_262230chr11_62672873_+UTR3
ADediting_262231chr11_62672934_+UTR3
ADediting_262232chr11_62672948_+UTR3
ADediting_262233chr11_62672989_+UTR3
ADediting_262234chr11_62672992_+UTR3
ADediting_262235chr11_62673016_+UTR3
ADediting_262236chr11_62673081_+UTR3
ADediting_1527354chr11_62672859_+UTR3
ADediting_1527355chr11_62672888_+UTR3
ADediting_1527356chr11_62673041_+UTR3

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_262216chr11_62672566_+SINEAluName=AluSx
ADediting_262217chr11_62672585_+SINEAluName=AluSx
ADediting_262218chr11_62672604_+SINEAluName=AluSx
ADediting_262219chr11_62672607_+SINEAluName=AluSx
ADediting_262220chr11_62672608_+SINEAluName=AluSx
ADediting_262221chr11_62672633_+SINEAluName=AluSx
ADediting_262222chr11_62672643_+SINEAluName=AluSx
ADediting_262223chr11_62672646_+SINEAluName=AluSx
ADediting_262224chr11_62672660_+SINEAluName=AluSx
ADediting_262225chr11_62672684_+SINEAluName=AluSx
ADediting_262226chr11_62672693_+SINEAluName=AluSx
ADediting_262227chr11_62672703_+SINEAluName=AluSx
ADediting_262228chr11_62672712_+SINEAluName=AluSx
ADediting_262229chr11_62672776_+SINEAluName=AluSx
ADediting_262230chr11_62672873_+SINEAluName=AluSq2
ADediting_262231chr11_62672934_+SINEAluName=AluSq2
ADediting_262232chr11_62672948_+SINEAluName=AluSq2
ADediting_262233chr11_62672989_+SINEAluName=AluSq2
ADediting_262234chr11_62672992_+SINEAluName=AluSq2
ADediting_262235chr11_62673016_+SINEAluName=AluSq2
ADediting_262236chr11_62673081_+SINEAluName=AluSq2
ADediting_1527354chr11_62672859_+SINEAluName=AluSq2
ADediting_1527355chr11_62672888_+SINEAluName=AluSq2
ADediting_1527356chr11_62673041_+SINEAluName=AluSq2

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RNA A-to-I editing events in the alternative splicing sites for UQCC3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for UQCC3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
boxplot
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs