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| Differntial gene expression between RNA A-to-I edited versus non-edited samples |
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| The effects of the RNA editing to the stability of the RNA structures |
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Gene summary for SLC25A23 |
 Gene summary |
| Gene information | Gene symbol | SLC25A23 | Gene ID | 79085 |
| Gene name | solute carrier family 25 member 23 | |
| Synonyms | APC2|MCSC2|SCaMC-3 | |
| Cytomap | 19p13.3 | |
| Type of gene | protein-coding | |
| Description | calcium-binding mitochondrial carrier protein SCaMC-3mitochondrial ATP-Mg/Pi carrier protein 2mitochondrial Ca(2+)-dependent solute carrier protein 2mitochondrial Ca2+-dependent solute carrier protein 2short calcium-binding mitochondrial carrier 3sma | |
| Modification date | 20200313 | |
| UniProtAcc | ||
| Context |
| Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for SLC25A23 |
| RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. * This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA editing frequencies across three data sets. |
 |
| The number of RNA A-to-I editing events in different types of transcripts (# event, percentage). |
 |
| RNA A-to-I editing events in AD. |
| ADediting_790209(6436687, -), ADediting_790210(6436690, -), ADediting_790211(6436714, -), ADediting_790212(6436995, -), ADediting_790213(6437005, -), ADediting_790214(6437132, -), ADediting_790215(6437146, -), ADediting_790216(6437620, -), ADediting_790217(6437645, -), ADediting_790218(6437877, -), ADediting_790219(6438168, -), ADediting_790220(6438233, -), ADediting_790221(6438264, -), ADediting_790222(6438277, -), ADediting_790223(6438472, -), ADediting_790224(6438516, -), ADediting_790225(6438657, -), ADediting_790226(6438727, -), ADediting_790227(6438767, -), ADediting_790228(6438965, -), ADediting_790229(6439104, -), ADediting_790230(6439120, -), ADediting_790231(6441851, -), ADediting_790232(6443290, -), ADediting_790233(6443298, -), ADediting_790234(6443350, -), ADediting_790235(6443360, -), ADediting_790236(6444778, -), ADediting_790237(6444925, -), ADediting_790238(6444939, -), ADediting_790239(6445002, -), ADediting_790240(6445137, -), ADediting_790241(6445221, -), ADediting_790242(6445273, -), ADediting_790243(6445355, -), ADediting_790244(6445373, -), ADediting_790245(6445381, -), ADediting_790246(6445382, -), ADediting_790247(6445795, -), ADediting_790248(6445807, -), ADediting_790249(6445833, -), ADediting_790250(6445834, -), ADediting_790251(6445835, -), ADediting_790252(6445880, -), ADediting_790253(6445949, -), ADediting_790254(6445955, -), ADediting_790255(6445991, -), ADediting_790256(6445994, -), ADediting_790257(6446015, -), ADediting_790258(6446017, -), ADediting_790259(6446055, -), ADediting_790260(6446129, -), ADediting_790261(6446138, -), ADediting_790262(6446251, -), ADediting_790263(6446281, -), ADediting_790264(6446300, -), ADediting_790265(6447399, -), ADediting_790266(6447404, -), ADediting_790267(6447417, -), ADediting_790268(6447441, -), ADediting_790269(6447787, -), ADediting_790270(6447849, -), ADediting_790271(6447938, -), ADediting_790272(6447943, -), ADediting_790273(6448608, -), ADediting_790274(6448609, -), ADediting_790275(6448641, -), ADediting_790276(6448666, -), ADediting_790277(6448672, -), ADediting_790278(6448674, -), ADediting_790279(6448690, -), ADediting_790280(6448778, -), ADediting_790281(6448832, -), ADediting_790282(6448858, -), ADediting_790283(6448861, -), ADediting_790284(6448900, -), ADediting_790285(6448902, -), ADediting_790286(6448912, -), ADediting_790287(6448924, -), ADediting_790288(6448937, -), ADediting_790289(6448941, -), ADediting_790290(6448998, -), ADediting_790291(6449010, -), ADediting_790292(6449973, -), ADediting_790293(6449982, -), ADediting_790294(6449995, -), ADediting_790295(6450022, -), ADediting_790296(6450037, -), ADediting_790297(6450051, -), ADediting_790298(6450076, -), ADediting_790299(6450085, -), ADediting_790300(6450133, -), ADediting_790301(6450829, -), ADediting_790302(6450835, -), ADediting_790303(6450845, -), ADediting_790304(6450875, -), ADediting_790305(6450876, -), ADediting_790306(6450877, -), ADediting_790307(6450930, -), ADediting_790308(6450954, -), ADediting_790309(6450956, -), ADediting_790310(6450966, -), ADediting_790311(6450978, -), ADediting_790312(6451044, -), ADediting_790313(6451064, -), ADediting_790314(6451072, -), ADediting_790315(6451133, -), ADediting_790316(6451267, -), ADediting_790317(6451277, -), ADediting_790318(6451289, -), ADediting_790319(6451350, -), ADediting_790320(6451926, -), ADediting_790321(6451930, -), ADediting_790322(6451934, -), ADediting_790323(6451941, -), ADediting_790324(6451947, -), ADediting_790325(6451955, -), ADediting_790326(6451963, -), ADediting_790327(6451979, -), ADediting_790328(6451987, -), ADediting_790329(6451997, -), ADediting_790330(6452015, -), ADediting_790331(6452019, -), ADediting_790332(6452023, -), ADediting_790333(6452026, -), ADediting_790334(6453308, -), ADediting_790335(6453351, -), ADediting_790336(6453360, -), ADediting_790337(6453377, -), ADediting_790338(6453378, -), ADediting_790339(6453396, -), ADediting_790340(6453404, -), ADediting_790341(6453422, -), ADediting_790342(6453458, -), ADediting_790343(6453459, -), ADediting_790344(6453486, -), ADediting_790345(6453512, -), ADediting_790346(6455044, -), ADediting_790347(6455121, -), ADediting_790348(6455123, -), ADediting_790349(6455160, -), ADediting_790350(6455163, -), ADediting_790351(6455177, -), ADediting_790352(6455185, -), ADediting_790353(6455189, -), ADediting_790354(6455220, -), ADediting_790355(6455238, -), ADediting_790356(6455785, -), ADediting_790357(6455830, -), ADediting_790358(6455834, -), ADediting_790359(6455835, -), ADediting_790360(6455844, -), ADediting_790361(6455857, -), ADediting_790362(6455922, -), ADediting_790363(6455924, -), ADediting_790364(6455986, -), ADediting_790365(6455991, -), ADediting_790366(6455993, -), ADediting_790367(6455994, -), ADediting_790368(6456000, -), ADediting_1559811(6437207, -), ADediting_1559812(6438786, -), ADediting_1559813(6439294, -), ADediting_1559814(6439351, -), ADediting_1559815(6439358, -), ADediting_1559816(6445016, -), ADediting_1559817(6445346, -), ADediting_1559818(6445953, -), ADediting_1559819(6447621, -), ADediting_1559820(6447808, -), ADediting_1559821(6447835, -), ADediting_1559822(6448675, -), ADediting_1559823(6449806, -), ADediting_1559824(6450031, -), ADediting_1559825(6450033, -), ADediting_1559826(6450929, -), ADediting_1559827(6451270, -), ADediting_1559828(6453302, -), ADediting_1559829(6453418, -), ADediting_1559830(6453419, -), ADediting_1559831(6453441, -), ADediting_1559832(6453453, -), ADediting_1559833(6455032, -), ADediting_1559834(6455106, -), ADediting_1559835(6455203, -), ADediting_1559836(6455246, -), |
Top |
RNA editing positional annotations for SLC25A23 using Annovar |
| Protein coding RNA editing(s). |
| ADeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
| ADediting_1559812 | chr19_6438786_- | nonsynonymous SNV | ENST00000264088.8 | c.A1399G | p.T467A | . | . | . |
| ADediting_790226 | chr19_6438727_- | nonsynonymous SNV | ENST00000601322.5 | c.A250G | p.T84A | . | . | . |
| ADediting_790227 | chr19_6438767_- | nonsynonymous SNV | ENST00000264088.8 | c.A1418G | p.Q473R | . | . | . |
| ADediting_790364 | chr19_6455986_- | nonsynonymous SNV | ENST00000264088.8 | c.A590G | p.Q197R | . | . | . |
| ADediting_790365 | chr19_6455991_- | synonymous SNV | ENST00000264088.8 | c.A585G | p.K195K | . | . | . |
| ADediting_790366 | chr19_6455993_- | nonsynonymous SNV | ENST00000264088.8 | c.A583G | p.K195E | . | . | . |
| ADediting_790367 | chr19_6455994_- | synonymous SNV | ENST00000264088.8 | c.A582G | p.L194L | . | . | . |
| ADediting_790368 | chr19_6456000_- | synonymous SNV | ENST00000264088.8 | c.A576G | p.S192S | . | . | . |
| Gene structure information of RNA editing(s). |
| ADeditome ID | Position | Variant type |
| ADediting_790209 | chr19_6436687_- | intronic |
| ADediting_790210 | chr19_6436690_- | intronic |
| ADediting_790211 | chr19_6436714_- | intronic |
| ADediting_790212 | chr19_6436995_- | intronic |
| ADediting_790213 | chr19_6437005_- | intronic |
| ADediting_790214 | chr19_6437132_- | intronic |
| ADediting_790215 | chr19_6437146_- | intronic |
| ADediting_790216 | chr19_6437620_- | intronic |
| ADediting_790217 | chr19_6437645_- | intronic |
| ADediting_790218 | chr19_6437877_- | intronic |
| ADediting_790219 | chr19_6438168_- | intronic |
| ADediting_790220 | chr19_6438233_- | UTR3 |
| ADediting_790221 | chr19_6438264_- | UTR3 |
| ADediting_790222 | chr19_6438277_- | exonic |
| ADediting_790223 | chr19_6438472_- | exonic |
| ADediting_790224 | chr19_6438516_- | exonic |
| ADediting_790225 | chr19_6438657_- | intronic |
| ADediting_790226 | chr19_6438727_- | exonic |
| ADediting_790227 | chr19_6438767_- | exonic |
| ADediting_790228 | chr19_6438965_- | intronic |
| ADediting_790229 | chr19_6439104_- | intronic |
| ADediting_790230 | chr19_6439120_- | intronic |
| ADediting_790231 | chr19_6441851_- | UTR3 |
| ADediting_790232 | chr19_6443290_- | intronic |
| ADediting_790233 | chr19_6443298_- | intronic |
| ADediting_790234 | chr19_6443350_- | intronic |
| ADediting_790235 | chr19_6443360_- | intronic |
| ADediting_790236 | chr19_6444778_- | intronic |
| ADediting_790237 | chr19_6444925_- | intronic |
| ADediting_790238 | chr19_6444939_- | intronic |
| ADediting_790239 | chr19_6445002_- | intronic |
| ADediting_790240 | chr19_6445137_- | intronic |
| ADediting_790241 | chr19_6445221_- | intronic |
| ADediting_790242 | chr19_6445273_- | intronic |
| ADediting_790243 | chr19_6445355_- | intronic |
| ADediting_790244 | chr19_6445373_- | intronic |
| ADediting_790245 | chr19_6445381_- | intronic |
| ADediting_790246 | chr19_6445382_- | intronic |
| ADediting_790247 | chr19_6445795_- | intronic |
| ADediting_790248 | chr19_6445807_- | intronic |
| ADediting_790249 | chr19_6445833_- | intronic |
| ADediting_790250 | chr19_6445834_- | intronic |
| ADediting_790251 | chr19_6445835_- | intronic |
| ADediting_790252 | chr19_6445880_- | intronic |
| ADediting_790253 | chr19_6445949_- | intronic |
| ADediting_790254 | chr19_6445955_- | intronic |
| ADediting_790255 | chr19_6445991_- | intronic |
| ADediting_790256 | chr19_6445994_- | intronic |
| ADediting_790257 | chr19_6446015_- | intronic |
| ADediting_790258 | chr19_6446017_- | intronic |
| ADediting_790259 | chr19_6446055_- | intronic |
| ADediting_790260 | chr19_6446129_- | intronic |
| ADediting_790261 | chr19_6446138_- | intronic |
| ADediting_790262 | chr19_6446251_- | intronic |
| ADediting_790263 | chr19_6446281_- | intronic |
| ADediting_790264 | chr19_6446300_- | intronic |
| ADediting_790265 | chr19_6447399_- | intronic |
| ADediting_790266 | chr19_6447404_- | intronic |
| ADediting_790267 | chr19_6447417_- | intronic |
| ADediting_790268 | chr19_6447441_- | intronic |
| ADediting_790269 | chr19_6447787_- | intronic |
| ADediting_790270 | chr19_6447849_- | intronic |
| ADediting_790271 | chr19_6447938_- | intronic |
| ADediting_790272 | chr19_6447943_- | intronic |
| ADediting_790273 | chr19_6448608_- | intronic |
| ADediting_790274 | chr19_6448609_- | intronic |
| ADediting_790275 | chr19_6448641_- | intronic |
| ADediting_790276 | chr19_6448666_- | intronic |
| ADediting_790277 | chr19_6448672_- | intronic |
| ADediting_790278 | chr19_6448674_- | intronic |
| ADediting_790279 | chr19_6448690_- | intronic |
| ADediting_790280 | chr19_6448778_- | intronic |
| ADediting_790281 | chr19_6448832_- | intronic |
| ADediting_790282 | chr19_6448858_- | intronic |
| ADediting_790283 | chr19_6448861_- | intronic |
| ADediting_790284 | chr19_6448900_- | intronic |
| ADediting_790285 | chr19_6448902_- | intronic |
| ADediting_790286 | chr19_6448912_- | intronic |
| ADediting_790287 | chr19_6448924_- | intronic |
| ADediting_790288 | chr19_6448937_- | intronic |
| ADediting_790289 | chr19_6448941_- | intronic |
| ADediting_790290 | chr19_6448998_- | intronic |
| ADediting_790291 | chr19_6449010_- | intronic |
| ADediting_790292 | chr19_6449973_- | intronic |
| ADediting_790293 | chr19_6449982_- | intronic |
| ADediting_790294 | chr19_6449995_- | intronic |
| ADediting_790295 | chr19_6450022_- | intronic |
| ADediting_790296 | chr19_6450037_- | intronic |
| ADediting_790297 | chr19_6450051_- | intronic |
| ADediting_790298 | chr19_6450076_- | intronic |
| ADediting_790299 | chr19_6450085_- | intronic |
| ADediting_790300 | chr19_6450133_- | intronic |
| ADediting_790301 | chr19_6450829_- | intronic |
| ADediting_790302 | chr19_6450835_- | intronic |
| ADediting_790303 | chr19_6450845_- | intronic |
| ADediting_790304 | chr19_6450875_- | intronic |
| ADediting_790305 | chr19_6450876_- | intronic |
| ADediting_790306 | chr19_6450877_- | intronic |
| ADediting_790307 | chr19_6450930_- | intronic |
| ADediting_790308 | chr19_6450954_- | intronic |
| ADediting_790309 | chr19_6450956_- | intronic |
| ADediting_790310 | chr19_6450966_- | intronic |
| ADediting_790311 | chr19_6450978_- | intronic |
| ADediting_790312 | chr19_6451044_- | intronic |
| ADediting_790313 | chr19_6451064_- | intronic |
| ADediting_790314 | chr19_6451072_- | intronic |
| ADediting_790315 | chr19_6451133_- | intronic |
| ADediting_790316 | chr19_6451267_- | intronic |
| ADediting_790317 | chr19_6451277_- | intronic |
| ADediting_790318 | chr19_6451289_- | intronic |
| ADediting_790319 | chr19_6451350_- | intronic |
| ADediting_790320 | chr19_6451926_- | intronic |
| ADediting_790321 | chr19_6451930_- | intronic |
| ADediting_790322 | chr19_6451934_- | intronic |
| ADediting_790323 | chr19_6451941_- | intronic |
| ADediting_790324 | chr19_6451947_- | intronic |
| ADediting_790325 | chr19_6451955_- | intronic |
| ADediting_790326 | chr19_6451963_- | intronic |
| ADediting_790327 | chr19_6451979_- | intronic |
| ADediting_790328 | chr19_6451987_- | intronic |
| ADediting_790329 | chr19_6451997_- | intronic |
| ADediting_790330 | chr19_6452015_- | intronic |
| ADediting_790331 | chr19_6452019_- | intronic |
| ADediting_790332 | chr19_6452023_- | intronic |
| ADediting_790333 | chr19_6452026_- | intronic |
| ADediting_790334 | chr19_6453308_- | intronic |
| ADediting_790335 | chr19_6453351_- | intronic |
| ADediting_790336 | chr19_6453360_- | intronic |
| ADediting_790337 | chr19_6453377_- | intronic |
| ADediting_790338 | chr19_6453378_- | intronic |
| ADediting_790339 | chr19_6453396_- | intronic |
| ADediting_790340 | chr19_6453404_- | intronic |
| ADediting_790341 | chr19_6453422_- | intronic |
| ADediting_790342 | chr19_6453458_- | intronic |
| ADediting_790343 | chr19_6453459_- | intronic |
| ADediting_790344 | chr19_6453486_- | intronic |
| ADediting_790345 | chr19_6453512_- | intronic |
| ADediting_790346 | chr19_6455044_- | intronic |
| ADediting_790347 | chr19_6455121_- | intronic |
| ADediting_790348 | chr19_6455123_- | intronic |
| ADediting_790349 | chr19_6455160_- | intronic |
| ADediting_790350 | chr19_6455163_- | intronic |
| ADediting_790351 | chr19_6455177_- | intronic |
| ADediting_790352 | chr19_6455185_- | intronic |
| ADediting_790353 | chr19_6455189_- | intronic |
| ADediting_790354 | chr19_6455220_- | intronic |
| ADediting_790355 | chr19_6455238_- | intronic |
| ADediting_790356 | chr19_6455785_- | intronic |
| ADediting_790357 | chr19_6455830_- | intronic |
| ADediting_790358 | chr19_6455834_- | intronic |
| ADediting_790359 | chr19_6455835_- | intronic |
| ADediting_790360 | chr19_6455844_- | intronic |
| ADediting_790361 | chr19_6455857_- | intronic |
| ADediting_790362 | chr19_6455922_- | intronic |
| ADediting_790363 | chr19_6455924_- | intronic |
| ADediting_790364 | chr19_6455986_- | exonic |
| ADediting_790365 | chr19_6455991_- | exonic |
| ADediting_790366 | chr19_6455993_- | exonic |
| ADediting_790367 | chr19_6455994_- | exonic |
| ADediting_790368 | chr19_6456000_- | exonic |
| ADediting_1559811 | chr19_6437207_- | intronic |
| ADediting_1559812 | chr19_6438786_- | exonic |
| ADediting_1559813 | chr19_6439294_- | intronic |
| ADediting_1559814 | chr19_6439351_- | intronic |
| ADediting_1559815 | chr19_6439358_- | intronic |
| ADediting_1559816 | chr19_6445016_- | intronic |
| ADediting_1559817 | chr19_6445346_- | intronic |
| ADediting_1559818 | chr19_6445953_- | intronic |
| ADediting_1559819 | chr19_6447621_- | intronic |
| ADediting_1559820 | chr19_6447808_- | intronic |
| ADediting_1559821 | chr19_6447835_- | intronic |
| ADediting_1559822 | chr19_6448675_- | intronic |
| ADediting_1559823 | chr19_6449806_- | intronic |
| ADediting_1559824 | chr19_6450031_- | intronic |
| ADediting_1559825 | chr19_6450033_- | intronic |
| ADediting_1559826 | chr19_6450929_- | intronic |
| ADediting_1559827 | chr19_6451270_- | intronic |
| ADediting_1559828 | chr19_6453302_- | intronic |
| ADediting_1559829 | chr19_6453418_- | intronic |
| ADediting_1559830 | chr19_6453419_- | intronic |
| ADediting_1559831 | chr19_6453441_- | intronic |
| ADediting_1559832 | chr19_6453453_- | intronic |
| ADediting_1559833 | chr19_6455032_- | intronic |
| ADediting_1559834 | chr19_6455106_- | intronic |
| ADediting_1559835 | chr19_6455203_- | intronic |
| ADediting_1559836 | chr19_6455246_- | intronic |
| Repat-regional RNA editing(s). |
| ADeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
| ADediting_790209 | chr19_6436687_- | SINE | Alu | Name=AluSq |
| ADediting_790210 | chr19_6436690_- | SINE | Alu | Name=AluSq |
| ADediting_790211 | chr19_6436714_- | SINE | Alu | Name=AluSq |
| ADediting_790212 | chr19_6436995_- | SINE | Alu | Name=AluSz |
| ADediting_790213 | chr19_6437005_- | SINE | Alu | Name=AluSz |
| ADediting_790214 | chr19_6437132_- | SINE | Alu | Name=AluSz |
| ADediting_790215 | chr19_6437146_- | SINE | Alu | Name=AluSz |
| ADediting_790216 | chr19_6437620_- | SINE | Alu | Name=AluY |
| ADediting_790217 | chr19_6437645_- | SINE | Alu | Name=AluY |
| ADediting_790218 | chr19_6437877_- | SINE | Alu | Name=AluY |
| ADediting_790219 | chr19_6438168_- | SINE | Alu | Name=AluSz |
| ADediting_790220 | chr19_6438233_- | SINE | Alu | Name=AluSz |
| ADediting_790221 | chr19_6438264_- | SINE | Alu | Name=AluSz |
| ADediting_790222 | chr19_6438277_- | SINE | Alu | Name=AluSz |
| ADediting_790223 | chr19_6438472_- | SINE | Alu | Name=AluSz |
| ADediting_790224 | chr19_6438516_- | SINE | Alu | Name=AluSz |
| ADediting_790225 | chr19_6438657_- | SINE | Alu | Name=AluSq |
| ADediting_790226 | chr19_6438727_- | SINE | Alu | Name=AluSq |
| ADediting_790227 | chr19_6438767_- | SINE | Alu | Name=AluSq |
| ADediting_790228 | chr19_6438965_- | SINE | Alu | Name=AluSz |
| ADediting_790229 | chr19_6439104_- | SINE | Alu | Name=AluJb |
| ADediting_790230 | chr19_6439120_- | SINE | Alu | Name=AluJb |
| ADediting_790232 | chr19_6443290_- | SINE | Alu | Name=AluJo |
| ADediting_790233 | chr19_6443298_- | SINE | Alu | Name=AluJo |
| ADediting_790234 | chr19_6443350_- | SINE | Alu | Name=AluJo |
| ADediting_790235 | chr19_6443360_- | SINE | Alu | Name=AluJo |
| ADediting_790236 | chr19_6444778_- | SINE | Alu | Name=AluSc8 |
| ADediting_790237 | chr19_6444925_- | SINE | Alu | Name=AluSc8 |
| ADediting_790238 | chr19_6444939_- | SINE | Alu | Name=AluSc8 |
| ADediting_790239 | chr19_6445002_- | SINE | Alu | Name=FLAM_C |
| ADediting_790240 | chr19_6445137_- | SINE | Alu | Name=AluSq2 |
| ADediting_790241 | chr19_6445221_- | SINE | Alu | Name=AluSq2 |
| ADediting_790242 | chr19_6445273_- | SINE | Alu | Name=AluSq2 |
| ADediting_790243 | chr19_6445355_- | SINE | Alu | Name=AluSq2 |
| ADediting_790244 | chr19_6445373_- | SINE | Alu | Name=AluSq2 |
| ADediting_790245 | chr19_6445381_- | SINE | Alu | Name=AluSq2 |
| ADediting_790246 | chr19_6445382_- | SINE | Alu | Name=AluSq2 |
| ADediting_790247 | chr19_6445795_- | SINE | Alu | Name=AluJo |
| ADediting_790248 | chr19_6445807_- | SINE | Alu | Name=AluJo |
| ADediting_790249 | chr19_6445833_- | SINE | Alu | Name=AluJo |
| ADediting_790250 | chr19_6445834_- | SINE | Alu | Name=AluJo |
| ADediting_790251 | chr19_6445835_- | SINE | Alu | Name=AluJo |
| ADediting_790252 | chr19_6445880_- | SINE | Alu | Name=AluJo |
| ADediting_790253 | chr19_6445949_- | SINE | Alu | Name=AluJo |
| ADediting_790254 | chr19_6445955_- | SINE | Alu | Name=AluJo |
| ADediting_790255 | chr19_6445991_- | SINE | Alu | Name=AluJo |
| ADediting_790256 | chr19_6445994_- | SINE | Alu | Name=AluJo |
| ADediting_790257 | chr19_6446015_- | SINE | Alu | Name=AluJo |
| ADediting_790258 | chr19_6446017_- | SINE | Alu | Name=AluJo |
| ADediting_790259 | chr19_6446055_- | SINE | Alu | Name=AluJo |
| ADediting_790260 | chr19_6446129_- | SINE | Alu | Name=AluSq |
| ADediting_790261 | chr19_6446138_- | SINE | Alu | Name=AluSq |
| ADediting_790262 | chr19_6446251_- | SINE | Alu | Name=AluSq |
| ADediting_790263 | chr19_6446281_- | SINE | Alu | Name=AluSq |
| ADediting_790264 | chr19_6446300_- | SINE | Alu | Name=AluSq |
| ADediting_790265 | chr19_6447399_- | SINE | Alu | Name=AluSx3 |
| ADediting_790266 | chr19_6447404_- | SINE | Alu | Name=AluSx3 |
| ADediting_790267 | chr19_6447417_- | SINE | Alu | Name=AluSx3 |
| ADediting_790268 | chr19_6447441_- | SINE | Alu | Name=AluSx3 |
| ADediting_790269 | chr19_6447787_- | SINE | Alu | Name=AluSz |
| ADediting_790270 | chr19_6447849_- | SINE | Alu | Name=AluSz |
| ADediting_790271 | chr19_6447938_- | SINE | Alu | Name=AluSz |
| ADediting_790272 | chr19_6447943_- | SINE | Alu | Name=AluSz |
| ADediting_790273 | chr19_6448608_- | SINE | Alu | Name=AluSc |
| ADediting_790274 | chr19_6448609_- | SINE | Alu | Name=AluSc |
| ADediting_790275 | chr19_6448641_- | SINE | Alu | Name=AluSc |
| ADediting_790276 | chr19_6448666_- | SINE | Alu | Name=AluSc |
| ADediting_790277 | chr19_6448672_- | SINE | Alu | Name=AluSc |
| ADediting_790278 | chr19_6448674_- | SINE | Alu | Name=AluSc |
| ADediting_790279 | chr19_6448690_- | SINE | Alu | Name=AluSc |
| ADediting_790280 | chr19_6448778_- | SINE | Alu | Name=AluSz |
| ADediting_790281 | chr19_6448832_- | SINE | Alu | Name=AluSz |
| ADediting_790282 | chr19_6448858_- | SINE | Alu | Name=AluSz |
| ADediting_790283 | chr19_6448861_- | SINE | Alu | Name=AluSz |
| ADediting_790284 | chr19_6448900_- | SINE | Alu | Name=AluSz |
| ADediting_790285 | chr19_6448902_- | SINE | Alu | Name=AluSz |
| ADediting_790286 | chr19_6448912_- | SINE | Alu | Name=AluSz |
| ADediting_790287 | chr19_6448924_- | SINE | Alu | Name=AluSz |
| ADediting_790288 | chr19_6448937_- | SINE | Alu | Name=AluSz |
| ADediting_790289 | chr19_6448941_- | SINE | Alu | Name=AluSz |
| ADediting_790290 | chr19_6448998_- | SINE | Alu | Name=AluSz |
| ADediting_790291 | chr19_6449010_- | SINE | Alu | Name=AluSz |
| ADediting_790292 | chr19_6449973_- | SINE | Alu | Name=AluSx1 |
| ADediting_790293 | chr19_6449982_- | SINE | Alu | Name=AluSx1 |
| ADediting_790294 | chr19_6449995_- | SINE | Alu | Name=AluSx1 |
| ADediting_790295 | chr19_6450022_- | SINE | Alu | Name=AluSx1 |
| ADediting_790296 | chr19_6450037_- | SINE | Alu | Name=AluSx1 |
| ADediting_790297 | chr19_6450051_- | SINE | Alu | Name=AluSx1 |
| ADediting_790298 | chr19_6450076_- | SINE | Alu | Name=AluSx1 |
| ADediting_790299 | chr19_6450085_- | SINE | Alu | Name=AluSx1 |
| ADediting_790300 | chr19_6450133_- | SINE | Alu | Name=AluSx1 |
| ADediting_790301 | chr19_6450829_- | SINE | Alu | Name=AluSx1 |
| ADediting_790302 | chr19_6450835_- | SINE | Alu | Name=AluSx1 |
| ADediting_790303 | chr19_6450845_- | SINE | Alu | Name=AluSx1 |
| ADediting_790304 | chr19_6450875_- | SINE | Alu | Name=AluSx1 |
| ADediting_790305 | chr19_6450876_- | SINE | Alu | Name=AluSx1 |
| ADediting_790306 | chr19_6450877_- | SINE | Alu | Name=AluSx1 |
| ADediting_790307 | chr19_6450930_- | SINE | Alu | Name=AluSx1 |
| ADediting_790308 | chr19_6450954_- | SINE | Alu | Name=AluSx1 |
| ADediting_790309 | chr19_6450956_- | SINE | Alu | Name=AluSx1 |
| ADediting_790310 | chr19_6450966_- | SINE | Alu | Name=AluSx1 |
| ADediting_790311 | chr19_6450978_- | SINE | Alu | Name=AluSx1 |
| ADediting_790312 | chr19_6451044_- | SINE | Alu | Name=AluSx1 |
| ADediting_790313 | chr19_6451064_- | SINE | Alu | Name=AluSx1 |
| ADediting_790314 | chr19_6451072_- | SINE | Alu | Name=AluSx1 |
| ADediting_790315 | chr19_6451133_- | SINE | Alu | Name=AluSz |
| ADediting_790316 | chr19_6451267_- | SINE | Alu | Name=AluSz |
| ADediting_790317 | chr19_6451277_- | SINE | Alu | Name=AluSz |
| ADediting_790318 | chr19_6451289_- | SINE | Alu | Name=AluSz |
| ADediting_790319 | chr19_6451350_- | SINE | Alu | Name=AluSz |
| ADediting_790320 | chr19_6451926_- | SINE | Alu | Name=AluSx |
| ADediting_790321 | chr19_6451930_- | SINE | Alu | Name=AluSx |
| ADediting_790322 | chr19_6451934_- | SINE | Alu | Name=AluSx |
| ADediting_790323 | chr19_6451941_- | SINE | Alu | Name=AluSx |
| ADediting_790324 | chr19_6451947_- | SINE | Alu | Name=AluSx |
| ADediting_790325 | chr19_6451955_- | SINE | Alu | Name=AluSx |
| ADediting_790326 | chr19_6451963_- | SINE | Alu | Name=AluSx |
| ADediting_790327 | chr19_6451979_- | SINE | Alu | Name=AluSx |
| ADediting_790328 | chr19_6451987_- | SINE | Alu | Name=AluSx |
| ADediting_790329 | chr19_6451997_- | SINE | Alu | Name=AluSx |
| ADediting_790330 | chr19_6452015_- | SINE | Alu | Name=AluSx |
| ADediting_790331 | chr19_6452019_- | SINE | Alu | Name=AluSx |
| ADediting_790332 | chr19_6452023_- | SINE | Alu | Name=AluSx |
| ADediting_790333 | chr19_6452026_- | SINE | Alu | Name=AluSx |
| ADediting_790334 | chr19_6453308_- | SINE | Alu | Name=AluSx1 |
| ADediting_790335 | chr19_6453351_- | SINE | Alu | Name=AluSx1 |
| ADediting_790336 | chr19_6453360_- | SINE | Alu | Name=AluSx1 |
| ADediting_790337 | chr19_6453377_- | SINE | Alu | Name=AluSx1 |
| ADediting_790338 | chr19_6453378_- | SINE | Alu | Name=AluSx1 |
| ADediting_790339 | chr19_6453396_- | SINE | Alu | Name=AluSx1 |
| ADediting_790340 | chr19_6453404_- | SINE | Alu | Name=AluSx1 |
| ADediting_790341 | chr19_6453422_- | SINE | Alu | Name=AluSx1 |
| ADediting_790342 | chr19_6453458_- | SINE | Alu | Name=AluSx1 |
| ADediting_790343 | chr19_6453459_- | SINE | Alu | Name=AluSx1 |
| ADediting_790344 | chr19_6453486_- | SINE | Alu | Name=AluSx1 |
| ADediting_790345 | chr19_6453512_- | SINE | Alu | Name=AluSx1 |
| ADediting_790346 | chr19_6455044_- | SINE | Alu | Name=AluJr |
| ADediting_790347 | chr19_6455121_- | SINE | Alu | Name=AluJr |
| ADediting_790348 | chr19_6455123_- | SINE | Alu | Name=AluJr |
| ADediting_790349 | chr19_6455160_- | SINE | Alu | Name=AluJr |
| ADediting_790350 | chr19_6455163_- | SINE | Alu | Name=AluJr |
| ADediting_790351 | chr19_6455177_- | SINE | Alu | Name=AluJr |
| ADediting_790352 | chr19_6455185_- | SINE | Alu | Name=AluJr |
| ADediting_790353 | chr19_6455189_- | SINE | Alu | Name=AluJr |
| ADediting_790354 | chr19_6455220_- | SINE | Alu | Name=AluJr |
| ADediting_790355 | chr19_6455238_- | SINE | Alu | Name=AluJr |
| ADediting_790356 | chr19_6455785_- | SINE | Alu | Name=AluY |
| ADediting_790357 | chr19_6455830_- | SINE | Alu | Name=AluY |
| ADediting_790358 | chr19_6455834_- | SINE | Alu | Name=AluY |
| ADediting_790359 | chr19_6455835_- | SINE | Alu | Name=AluY |
| ADediting_790360 | chr19_6455844_- | SINE | Alu | Name=AluY |
| ADediting_790361 | chr19_6455857_- | SINE | Alu | Name=AluY |
| ADediting_790362 | chr19_6455922_- | SINE | Alu | Name=AluY |
| ADediting_790363 | chr19_6455924_- | SINE | Alu | Name=AluY |
| ADediting_790364 | chr19_6455986_- | SINE | Alu | Name=AluY |
| ADediting_790365 | chr19_6455991_- | SINE | Alu | Name=AluY |
| ADediting_790366 | chr19_6455993_- | SINE | Alu | Name=AluY |
| ADediting_790367 | chr19_6455994_- | SINE | Alu | Name=AluY |
| ADediting_790368 | chr19_6456000_- | SINE | Alu | Name=AluY |
| ADediting_1559811 | chr19_6437207_- | SINE | Alu | Name=AluJb |
| ADediting_1559812 | chr19_6438786_- | SINE | Alu | Name=AluSq |
| ADediting_1559813 | chr19_6439294_- | SINE | Alu | Name=AluJr |
| ADediting_1559814 | chr19_6439351_- | SINE | Alu | Name=AluJr |
| ADediting_1559815 | chr19_6439358_- | SINE | Alu | Name=AluJr |
| ADediting_1559816 | chr19_6445016_- | SINE | Alu | Name=FLAM_C |
| ADediting_1559817 | chr19_6445346_- | SINE | Alu | Name=AluSq2 |
| ADediting_1559818 | chr19_6445953_- | SINE | Alu | Name=AluJo |
| ADediting_1559819 | chr19_6447621_- | SINE | Alu | Name=AluSx |
| ADediting_1559820 | chr19_6447808_- | SINE | Alu | Name=AluSz |
| ADediting_1559821 | chr19_6447835_- | SINE | Alu | Name=AluSz |
| ADediting_1559822 | chr19_6448675_- | SINE | Alu | Name=AluSc |
| ADediting_1559823 | chr19_6449806_- | SINE | Alu | Name=AluJr |
| ADediting_1559824 | chr19_6450031_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559825 | chr19_6450033_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559826 | chr19_6450929_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559827 | chr19_6451270_- | SINE | Alu | Name=AluSz |
| ADediting_1559828 | chr19_6453302_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559829 | chr19_6453418_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559830 | chr19_6453419_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559831 | chr19_6453441_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559832 | chr19_6453453_- | SINE | Alu | Name=AluSx1 |
| ADediting_1559833 | chr19_6455032_- | SINE | Alu | Name=AluJr |
| ADediting_1559834 | chr19_6455106_- | SINE | Alu | Name=AluJr |
| ADediting_1559835 | chr19_6455203_- | SINE | Alu | Name=AluJr |
| ADediting_1559836 | chr19_6455246_- | SINE | Alu | Name=AluJr |
Top |
RNA A-to-I editing events in the alternative splicing sites for SLC25A23 |
| RNA A-to-I editing(s) in the alternative splicing sites. |
| AStype | ADeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
| A3SS | ADediting_1559812 | chr19_6438786_- | 6438769:6438791 | 3ss | 15i | CTGCAACCTCTGCCTTCCAGGTT | 7.73 | CTGCAGCCTCTGCCTTCCAGGTT | 7.01 |
| A3SS | ADediting_1559812 | chr19_6438786_- | 6438769:6438791 | 3ss | 15i | CTGCAACCTCTGCCTTCCAGGTT | 7.73 | CTGCAGCCTCTGCCTTCCAGGTT | 7.01 |
| A3SS | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| A3SS | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| A3SS | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| A3SS | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| A3SS | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ES | ADediting_1559812 | chr19_6438786_- | 6438769:6438791 | 3ss | 15i | CTGCAACCTCTGCCTTCCAGGTT | 7.73 | CTGCAGCCTCTGCCTTCCAGGTT | 7.01 |
| ES | ADediting_1559812 | chr19_6438786_- | 6438769:6438791 | 3ss | 15i | CTGCAACCTCTGCCTTCCAGGTT | 7.73 | CTGCAGCCTCTGCCTTCCAGGTT | 7.01 |
| ES | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ES | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ES | ADediting_790362 | chr19_6455922_- | 6455914:6455922 | 5ss | 3e | ATGGTGAAA | 0.56 | GTGGTGAAA | -1.77 |
| ME1 | ADediting_790227 | chr19_6438767_- | 6438766:6438774 | 5ss | 5i | CAGGTTCAA | 1.19 | CAGGTTCGA | 5.36 |
| ME2 | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ME2 | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ME2 | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ME2 | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| ME2 | ADediting_790224 | chr19_6438516_- | 6438512:6438534 | 3ss | 2i | GATTTCATCATGTTGCCCAGGCT | 2.51 | GATTTCATCATGTTGCCCGGGCT | -5.44 |
| Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for SLC25A23 |
| Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event. * The grey color means N/A. |
| Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event. |
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| - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
| - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples. * Click on the image to enlarge it in a new window. |
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| ADeditome ID | Chr | Positoing | Skipped exon | ENSG | ENSTs |
Top |
Protein coding region RNA A-to-I editings for SLC25A23 |
| - Lollipop plot for RNA A-to-I editings across protein structure. * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for SLC25A23 |
| RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure. |
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| RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_790231 | chr19_6441851_- | ENSG00000125648.15 | ENST00000301454.9 | SLC25A23-202 | hsa-miR-8078 | chr19 | 6441848 | 6441854 | 7mer-m8 | 6441847 | 6441869 | 145 | -19.44 |
| ADediting_790231 | chr19_6441851_- | ENSG00000125648.15 | ENST00000600682.5 | SLC25A23-211 | hsa-miR-8078 | chr19 | 6441848 | 6441854 | 7mer-m8 | 6441847 | 6441869 | 145 | -19.44 |
| RNA A-to-I editing in lncRNA gained miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559812 | chr19_6438786_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-17-3p | chr19 | 6438786 | 6438792 | 7mer-m8 | 6438785 | 6438806 | 150 | -15.7 |
| ADediting_1559812 | chr19_6438786_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-485-5p | chr19 | 6438782 | 6438788 | 7mer-m8 | 6438781 | 6438803 | 160 | -21.18 |
| ADediting_1559812 | chr19_6438786_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-6884-5p | chr19 | 6438782 | 6438788 | 7mer-m8 | 6438781 | 6438799 | 148 | -24.12 |
| RNA A-to-I editing in lncRNA lost miRNA binding sites. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1559812 | chr19_6438786_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-377-5p | chr19 | 6438782 | 6438788 | 7mer-m8 | 6438781 | 6438803 | 150 | -19.08 |
| ADediting_1559812 | chr19_6438786_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-6086 | chr19 | 6438782 | 6438788 | 7mer-m8 | 6438781 | 6438800 | 142 | -14.41 |
| ADediting_1559812 | chr19_6438786_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-6516-5p | chr19 | 6438786 | 6438792 | 7mer-m8 | 6438785 | 6438808 | 150 | -16.7 |
| ADediting_790226 | chr19_6438727_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-1537-5p | chr19 | 6436464 | 6438729 | 7mer-m8 | 6436463 | 6438741 | 155 | -17.71 |
| ADediting_790226 | chr19_6438727_- | ENSG00000125648.15 | ENST00000601760.1 | SLC25A23-213 | hsa-miR-2054 | chr19 | 6438725 | 6438731 | 7mer-m8 | 6438724 | 6438745 | 150 | -14.73 |
| RNA A-to-I editing in miRNAs gained binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs lost binding to lncRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_107020 | chr1_37500952_- | ENSG00000125648.15 | ENST00000301454.9 | SLC25A23-202 | hsa-miR-5581-3p | chr19 | 6440713 | 6440719 | 7mer-m8 | 6440712 | 6440733 | 140 | -14.26 |
| ADediting_107020 | chr1_37500952_- | ENSG00000125648.15 | ENST00000301454.9 | SLC25A23-202 | hsa-miR-5581-3p | chr19 | 6441476 | 6441482 | 7mer-m8 | 6441475 | 6441494 | 156 | -19.96 |
| ADediting_107020 | chr1_37500952_- | ENSG00000125648.15 | ENST00000600682.5 | SLC25A23-211 | hsa-miR-5581-3p | chr19 | 6441476 | 6441482 | 7mer-m8 | 6441475 | 6441494 | 156 | -19.96 |
| ADediting_1471004 | chr9_63819627_+ | ENSG00000125648.15 | ENST00000301454.9 | SLC25A23-202 | hsa-miR-4477b | chr19 | 6440390 | 6440397 | 8mer-1a | 6440390 | 6440412 | 143 | -11.35 |
| ADediting_1631458 | chr19_40282624_- | ENSG00000125648.15 | ENST00000301454.9 | SLC25A23-202 | hsa-miR-641 | chr19 | 6441418 | 6441424 | 7mer-1a | 6441418 | 6441441 | 142 | -19 |
| ADediting_496066 | chr15_66496985_- | ENSG00000125648.15 | ENST00000301454.9 | SLC25A23-202 | hsa-miR-4512 | chr19 | 6440851 | 6440858 | 8mer-1a | 6440851 | 6440872 | 150 | -15.25 |
| RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA. |
| ADeditom_ID | Position | ENSG | ENST | Transcript name | miRNA ID | Chromosome | Targt | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000125648.15 | ENST00000595810.5 | SLC25A23-206 | hsa-miR-5688 | chr19 | 6436160 | 6436166 | 7mer-m8 | 6436159 | 6436180 | 152 | -11.74 |
| ADediting_1097295 | chr3_85385762_+ | ENSG00000125648.15 | ENST00000598908.5 | SLC25A23-210 | hsa-miR-5688 | chr19 | 6436160 | 6436166 | 7mer-m8 | 6436159 | 6436180 | 152 | -11.74 |
| Differentially expressed gene-miRNA network |
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The effects of the RNA editing to the stability of the RNA structures for SLC25A23 |
| - RNA A-to-I editing in mRNA. * Click on the image to enlarge it in a new window. |
| ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
| ENST00000598908.5 | protein_coding |  |  |
| ENST00000601322.5 | protein_coding |  |  |
| ENST00000601760.1 | lncRNA |  |  |
| ENST00000600682.5 | protein_coding |  |  |
| ENST00000301454.9 | protein_coding |  |  |
| RNA A-to-I editing in miRNA. |
| ADeditom_ID | ENST | mir_ID | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| RNA A-to-I editing in mRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_790223 | ENST00000598908.5 | chr19_6438472_- | 479 | -322.10 | -322.00 | -324.20 |
| ADediting_790224 | ENST00000598908.5 | chr19_6438516_- | 435 | -324.10 | -322.00 | -324.20 |
| ADediting_790226 | ENST00000601322.5 | chr19_6438727_- | 250 | -168.30 | -166.30 | -170.50 |
| ADediting_790227 | ENST00000601322.5 | chr19_6438767_- | 210 | -170.70 | -166.30 | -170.50 |
| ADediting_790231 | ENST00000600682.5 | chr19_6441851_- | 833 | -449.60 | -443.00 | -449.60 |
| ADediting_790231 | ENST00000301454.9 | chr19_6441851_- | 1695 | -1319.90 | -1313.30 | -1319.90 |
| RNA A-to-I editing in lncRNA. |
| ADeditom_ID | ENST | Editing_Information | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
| ADediting_790226 | ENST00000601760.1 | chr19_6438727_- | 224 | -101.00 | -97.50 | -107.60 |
| ADediting_790227 | ENST00000601760.1 | chr19_6438767_- | 184 | -101.40 | -97.50 | -107.60 |
| ADediting_1559812 | ENST00000601760.1 | chr19_6438786_- | 165 | -100.20 | -97.50 | -107.60 |
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Relation with ADAR for SLC25A23 |
| Correlation between ADAR gene expression and RNA editing frequency |
| Tissue | ADeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| CER | ADediting_1559833 | chr19_6455032_- | 0.000703712865950217 | 0.273629529672776 | 1.54973029737549e-05 | 0.344848352099112 | 0.0317038025162296 | 0.175498206730744 |
| CER | ADediting_1559835 | chr19_6455203_- | 0.000442526856573045 | 0.2833311175773 | 1.05779400483731e-09 | 0.472206478656121 | 0.0161542953760175 | 0.196130237441651 |
| DLPFC | ADediting_790220 | chr19_6438233_- | 0.0116076833003731 | 0.143184235229172 | 0.670764228365104 | 0.0242383920985423 | 2.43433429524725e-16 | 0.443102862137866 |
| DLPFC | ADediting_790221 | chr19_6438264_- | 0.0639546857185634 | 0.105347309687644 | 0.441557592857147 | 0.0438645513452598 | 2.63070019853453e-13 | 0.399491734814279 |
| DLPFC | ADediting_790235 | chr19_6443360_- | 0.0282375108054773 | 0.124626436087827 | 0.97645601747231 | 0.00168298308166635 | 7.05605296509931e-19 | 0.475311849901892 |
| CER | ADediting_790235 | chr19_6443360_- | 0.187006507219799 | 0.108324497975224 | 7.39375664728672e-05 | 0.317825098870382 | 0.12435348162942 | 0.126028908894749 |
| CER | ADediting_790241 | chr19_6445221_- | 0.0632726716323482 | 0.152034567818738 | 3.07162515181427e-05 | 0.333327002789768 | 0.1170421332485 | 0.128514197300575 |
| DLPFC | ADediting_790247 | chr19_6445795_- | 0.212113685619364 | 0.0710662789542588 | 0.796333227436089 | -0.0147174988040971 | 1.32825132988035e-10 | 0.354376323578702 |
| CER | ADediting_790247 | chr19_6445795_- | 0.00541412324258395 | 0.226036530360265 | 2.87891427471648e-07 | 0.404314907192743 | 0.0935995036565458 | 0.137401991338097 |
| DLPFC | ADediting_790249 | chr19_6445833_- | 0.467878405078001 | 0.0413798587995753 | 0.69188823352601 | -0.0225963902251708 | 1.54669589253271e-08 | 0.314346222965503 |
| DLPFC | ADediting_790253 | chr19_6445949_- | 0.127093972658092 | 0.0868388425281813 | 0.798135981820166 | -0.0145843497433272 | 2.94722798209551e-10 | 0.34805645739466 |
| CER | ADediting_790255 | chr19_6445991_- | 0.00830894644467445 | 0.214769911729096 | 1.00141156371566e-06 | 0.386945746906649 | 0.0697082849270015 | 0.148516264992269 |
| DLPFC | ADediting_790258 | chr19_6446017_- | 0.286386459942572 | 0.0607388536910932 | 0.823388119965815 | 0.0127272061412483 | 2.95073591033992e-10 | 0.348046919068102 |
| CER | ADediting_790258 | chr19_6446017_- | 0.00613310260977864 | 0.222811139690052 | 5.90133519117857e-07 | 0.394435230631265 | 0.688734372793227 | 0.0329736083556643 |
| DLPFC | ADediting_790259 | chr19_6446055_- | 0.377058210540994 | 0.0503412996112907 | 0.594004896145103 | -0.030390495570805 | 2.28398963508517e-12 | 0.384601315957761 |
| DLPFC | ADediting_790260 | chr19_6446129_- | 0.149580295077576 | 0.0820375798709544 | 0.649275754724821 | -0.0259295238645436 | 3.54741398934123e-11 | 0.364547316620725 |
| DLPFC | ADediting_790282 | chr19_6448858_- | 0.914814462277608 | 0.00609995311104581 | 0.141704632908048 | -0.0836520271260014 | 9.43551604445380e-09 | 0.318785021527686 |
| DLPFC | ADediting_790283 | chr19_6448861_- | 0.956749463499947 | -0.00309271857705124 | 0.0188821129162702 | -0.133291845564626 | 1.07464266381167e-09 | 0.33748760604576 |
| DLPFC | ADediting_790285 | chr19_6448902_- | 0.182618119103807 | 0.0758917562653513 | 0.16198753781671 | -0.0796203165326588 | 9.05592646935105e-17 | 0.448798104814438 |
| DLPFC | ADediting_790286 | chr19_6448912_- | 0.771923045634191 | -0.0165286107304274 | 0.0619317067034699 | -0.106155299485507 | 4.97908479043817e-11 | 0.361969606696371 |
| DLPFC | ADediting_790287 | chr19_6448924_- | 0.409107628019404 | 0.0470473561410003 | 0.0958641119681642 | -0.0947493745040952 | 1.76703211419932e-11 | 0.369775036204481 |
| DLPFC | ADediting_790289 | chr19_6448941_- | 0.986984921573667 | 0.000930257216539624 | 0.0442390061711912 | -0.114350532193626 | 4.58752638053191e-14 | 0.411002489328967 |
| DLPFC | ADediting_790298 | chr19_6450076_- | 0.506451965057366 | 0.0378732776851765 | 0.347296716964742 | -0.0535576873572943 | 2.82951898678865e-11 | 0.366253798506601 |
| CER | ADediting_790301 | chr19_6450829_- | 0.0134021238285771 | 0.201521408548168 | 2.40436906164488e-06 | 0.374118361531768 | 0.011038402484231 | 0.206990209533605 |
| CER | ADediting_790302 | chr19_6450835_- | 0.00537284982967546 | 0.226233080924524 | 1.10899939514261e-05 | 0.350322390367748 | 0.117143743723108 | 0.128478843295198 |
| DLPFC | ADediting_790319 | chr19_6451350_- | 0.384449063336943 | 0.0495670996919462 | 0.469251635665805 | -0.0412523899344858 | 1.81548030863413e-10 | 0.351915139815226 |
| CER | ADediting_790325 | chr19_6451955_- | 0.0217693216905094 | 0.187240800291179 | 2.18819706282194e-05 | 0.339095303846496 | 0.0739905266050293 | 0.146319007286985 |
| CER | ADediting_790336 | chr19_6453360_- | 0.0196352306215133 | 0.1903557979164 | 0.000169116491937826 | 0.30240638963994 | 0.0188512893226948 | 0.191573905678403 |
| CER | ADediting_790338 | chr19_6453378_- | 0.00117837675514212 | 0.262414185080751 | 2.65244930715906e-05 | 0.3358367418687 | 0.0523643993861904 | 0.158732657202433 |
| CER | ADediting_790343 | chr19_6453459_- | 0.0157581986802178 | 0.19685427318472 | 2.00190868539884e-07 | 0.409196677050636 | 0.0436839966962435 | 0.164946336111036 |
| CER | ADediting_790344 | chr19_6453486_- | 0.00319779011123132 | 0.239204322654307 | 5.98829411526121e-06 | 0.360144718183595 | 0.128571708065634 | 0.124646027706733 |
| CER | ADediting_790346 | chr19_6455044_- | 0.00126185810366961 | 0.260888287530482 | 9.38113095410985e-07 | 0.387880562366006 | 0.107367728399411 | 0.131995532646674 |
| CER | ADediting_790349 | chr19_6455160_- | 0.00542908806444984 | 0.225965596149472 | 1.5935817959405e-06 | 0.380209923671933 | 0.0066922819945896 | 0.220528045008077 |
| CER | ADediting_790351 | chr19_6455177_- | 0.000181157061521839 | 0.301085567763698 | 1.94548367001597e-08 | 0.438803324485857 | 0.0203704644222822 | 0.189250999435704 |
| CER | ADediting_790353 | chr19_6455189_- | 0.00214778907370245 | 0.248713437470945 | 2.38895472080576e-06 | 0.374214571514936 | 0.00844802682765317 | 0.21432230974427 |
| CER | ADediting_790354 | chr19_6455220_- | 0.00129672626016847 | 0.260278130919263 | 6.01917474277136e-05 | 0.321530971079925 | 0.0310449129660374 | 0.176171413512341 |
| CER | ADediting_790355 | chr19_6455238_- | 1.1250513453611e-05 | 0.350089390186852 | 7.61206620272697e-06 | 0.35635913512664 | 0.0191488106454581 | 0.191106538858342 |
| CER | ADediting_790357 | chr19_6455830_- | 0.0391272033128897 | 0.168633231899922 | 1.81796234281068e-05 | 0.342200420754547 | 0.15652139718977 | 0.116266715775466 |
| CER | ADediting_790359 | chr19_6455835_- | 0.161322589219742 | 0.114943692509408 | 0.00018523253883415 | 0.300656963468579 | 0.240010715687703 | 0.0965183426839346 |
| CER | ADediting_790360 | chr19_6455844_- | 0.0258947783689723 | 0.181899384365164 | 1.23666059734824e-05 | 0.348551170914656 | 0.0367866658574022 | 0.170669366157966 |
| CER | ADediting_790361 | chr19_6455857_- | 0.0137067599128464 | 0.200879391056001 | 0.000158876717604592 | 0.30360047195042 | 0.904071913159698 | 0.00992311657883981 |
| CER | ADediting_790363 | chr19_6455924_- | 0.00307897856817267 | 0.240124589042442 | 1.51228955264653e-09 | 0.468294428662439 | 0.0217309322639462 | 0.187294460554061 |
| CER | ADediting_790367 | chr19_6455994_- | 0.0523190158865778 | 0.158762839703637 | 5.5403280319835e-05 | 0.323010999073209 | 0.341286444065125 | 0.0782352784655578 |
| Correlation between ADAR gene expression and this gene's expression |
| Tissue | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
| DLPFC | 4.16623873801449e-40 | 0.659749199812639 | 4.85053545598776e-55 | 0.740235177161498 | 6.78295026999047e-11 | 0.359598656055131 |
| AC | 5.07525226987867e-68 | 0.840719751226115 | 5.77231649818435e-94 | 0.904871167549144 | 1.95491461182048e-05 | 0.266493028151509 |
| PCC | 1.27312191826419e-32 | 0.726497853435231 | 4.90110913112729e-30 | 0.705160029773978 | 0.00117648794812154 | 0.233053841871246 |
| CER | 7.8942091503718e-16 | 0.596582755150328 | 1.55728002952171e-14 | 0.574246528612162 | 0.0402920730169029 | 0.167657799278471 |
| TCX | 4.442011818345e-19 | 0.645949354663389 | 2.5076560934749e-23 | 0.699198666942261 | 0.00548073215908101 | -0.225722134338092 |
| FP | 2.53718862651422e-12 | 0.493632135969922 | 2.66620033826381e-05 | 0.309248734773718 | 5.92000979650956e-09 | 0.418879150289536 |
| IFG | 5.8067566677681e-07 | 0.818301257392891 | 6.54298362718203e-07 | 0.816232241490196 | 0.0917570617097167 | 0.34446458123971 |
| STG | 7.43401317804909e-09 | 0.57992290748529 | 1.86708780890836e-06 | 0.493275723494266 | 0.00502423316572484 | 0.303398022518688 |
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Relation with AD stages for SLC25A23 |
| Correlation between AD stages and RNA editing frequency |
| Tissue | ADeditomID | position | P-val | Coeff. |
| CER | ADediting_790346 | chr19_6455044_- | 0.000331068442744956 | 0.339072461805015 |
| CER | ADediting_790347 | chr19_6455121_- | 0.00022451537491441 | 0.347930673301959 |
| CER | ADediting_790351 | chr19_6455177_- | 1.44122120418336e-05 | 0.404130253212006 |
| CER | ADediting_790353 | chr19_6455189_- | 0.000886571053289793 | 0.31534294921579 |
| CER | ADediting_790354 | chr19_6455220_- | 0.00151659567985054 | 0.301548887114381 |
| CER | ADediting_790363 | chr19_6455924_- | 0.000293304972791172 | 0.341863031526665 |
| CER | ADediting_1559835 | chr19_6455203_- | 0.0003180033721582 | 0.340003070075696 |
| IFG | ADediting_790224 | chr19_6438516_- | 0.0138806839050487 | -0.48551999521549 |
| Correlation between AD stages and this gene's expression |
| Tissue | P-val | Coeff. |
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RelatedDrugs for SLC25A23 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.0 2018-04-02) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLC25A23 |
| Diseases associated with this gene. (DisGeNet 4.0) |
| Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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