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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for ERI3

check button Gene summary
Gene informationGene symbol

ERI3

Gene ID

79033

Gene nameERI1 exoribonuclease family member 3
SynonymsPINT1|PRNPIP
Cytomap

1p34.1

Type of geneprotein-coding
DescriptionERI1 exoribonuclease 3enhanced RNAi three prime mRNA exonuclease homolog 3prion interactor 1prion protein-interacting protein
Modification date20200313
UniProtAcc

O43414,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ERI3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_115913(44231465, -), ADediting_115914(44231512, -), ADediting_115915(44231568, -), ADediting_115916(44231621, -), ADediting_115917(44233489, -), ADediting_115918(44233501, -), ADediting_115919(44233519, -), ADediting_115920(44233520, -), ADediting_115921(44233532, -), ADediting_115922(44234537, -), ADediting_115923(44234559, -), ADediting_115924(44234602, -), ADediting_115925(44234612, -), ADediting_115926(44234617, -), ADediting_115927(44234628, -), ADediting_115928(44234651, -), ADediting_115929(44234653, -), ADediting_115930(44234806, -), ADediting_115931(44234880, -), ADediting_115932(44234881, -), ADediting_115933(44242128, -), ADediting_115934(44278221, -), ADediting_115935(44278233, -), ADediting_115936(44278365, -), ADediting_115937(44278369, -), ADediting_115938(44278377, -), ADediting_115939(44278415, -), ADediting_115940(44278444, -), ADediting_115941(44278445, -), ADediting_115942(44278446, -), ADediting_115943(44278639, -), ADediting_115944(44279290, -), ADediting_115945(44279317, -), ADediting_115946(44279332, -), ADediting_115947(44279336, -), ADediting_115948(44279405, -), ADediting_115949(44279408, -), ADediting_115950(44279425, -), ADediting_115951(44279433, -), ADediting_115952(44279445, -), ADediting_115953(44279463, -), ADediting_115954(44279476, -), ADediting_115955(44279482, -), ADediting_115956(44279493, -), ADediting_115957(44279498, -), ADediting_115958(44279499, -), ADediting_115959(44279505, -), ADediting_115960(44281337, -), ADediting_115961(44281367, -), ADediting_115962(44281370, -), ADediting_115963(44281385, -), ADediting_115964(44281417, -), ADediting_115965(44281422, -), ADediting_115966(44281493, -), ADediting_115967(44281506, -), ADediting_115968(44281541, -), ADediting_115969(44281547, -), ADediting_115970(44299392, -), ADediting_115971(44299459, -), ADediting_115972(44299465, -), ADediting_115973(44299477, -), ADediting_115974(44309419, -), ADediting_115975(44309443, -), ADediting_115976(44341652, -), ADediting_115977(44341721, -), ADediting_115978(44341778, -), ADediting_115979(44341781, -), ADediting_115980(44341782, -), ADediting_115981(44341790, -), ADediting_115982(44341795, -), ADediting_115983(44341807, -), ADediting_115984(44341808, -), ADediting_115985(44341822, -), ADediting_115986(44341833, -), ADediting_115987(44341838, -), ADediting_115988(44342715, -), ADediting_115989(44342744, -), ADediting_115990(44342761, -), ADediting_115991(44342768, -), ADediting_115992(44342775, -), ADediting_115993(44342912, -), ADediting_115994(44342927, -), ADediting_115995(44342932, -), ADediting_115996(44342959, -), ADediting_115997(44342960, -), ADediting_115998(44342981, -), ADediting_115999(44342982, -), ADediting_116000(44344047, -), ADediting_116001(44344073, -), ADediting_116002(44344076, -), ADediting_116003(44344117, -), ADediting_116004(44344155, -), ADediting_116005(44344156, -), ADediting_116006(44344162, -), ADediting_116007(44344175, -), ADediting_116008(44349317, -), ADediting_116009(44349322, -), ADediting_116010(44349327, -), ADediting_116011(44350426, -), ADediting_116012(44350455, -), ADediting_116013(44350499, -), ADediting_116014(44350861, -), ADediting_116015(44351139, -), ADediting_116016(44351155, -), ADediting_116017(44351171, -), ADediting_116018(44351174, -), ADediting_116019(44351190, -), ADediting_116020(44351198, -), ADediting_116021(44351203, -), ADediting_116022(44351271, -), ADediting_116023(44351325, -), ADediting_116024(44352310, -), ADediting_1520146(44231619, -), ADediting_1520147(44234775, -), ADediting_1520148(44234779, -), ADediting_1520149(44234816, -), ADediting_1520150(44234871, -), ADediting_1520151(44234875, -), ADediting_1520152(44278644, -), ADediting_1520153(44278876, -), ADediting_1520154(44279365, -), ADediting_1600950(44278305, -), ADediting_1600951(44278308, -), ADediting_1600952(44278311, -), ADediting_1600953(44278333, -), ADediting_1600954(44278394, -), ADediting_1600955(44278420, -), ADediting_1600956(44278799, -), ADediting_1600957(44278816, -), ADediting_1600958(44278830, -), ADediting_1600959(44278875, -), ADediting_1600960(44292084, -), ADediting_1600961(44292086, -), ADediting_1600962(44292113, -), ADediting_1600963(44298652, -), ADediting_1600964(44309351, -), ADediting_1600965(44309355, -), ADediting_1600966(44309363, -),

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RNA editing positional annotations for ERI3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_115913chr1_44231465_-intronic
ADediting_115914chr1_44231512_-intronic
ADediting_115915chr1_44231568_-intronic
ADediting_115916chr1_44231621_-intronic
ADediting_115917chr1_44233489_-intronic
ADediting_115918chr1_44233501_-intronic
ADediting_115919chr1_44233519_-intronic
ADediting_115920chr1_44233520_-intronic
ADediting_115921chr1_44233532_-intronic
ADediting_115922chr1_44234537_-intronic
ADediting_115923chr1_44234559_-intronic
ADediting_115924chr1_44234602_-intronic
ADediting_115925chr1_44234612_-intronic
ADediting_115926chr1_44234617_-intronic
ADediting_115927chr1_44234628_-intronic
ADediting_115928chr1_44234651_-intronic
ADediting_115929chr1_44234653_-intronic
ADediting_115930chr1_44234806_-intronic
ADediting_115931chr1_44234880_-intronic
ADediting_115932chr1_44234881_-intronic
ADediting_115933chr1_44242128_-intronic
ADediting_115934chr1_44278221_-intronic
ADediting_115935chr1_44278233_-intronic
ADediting_115936chr1_44278365_-intronic
ADediting_115937chr1_44278369_-intronic
ADediting_115938chr1_44278377_-intronic
ADediting_115939chr1_44278415_-intronic
ADediting_115940chr1_44278444_-intronic
ADediting_115941chr1_44278445_-intronic
ADediting_115942chr1_44278446_-intronic
ADediting_115943chr1_44278639_-intronic
ADediting_115944chr1_44279290_-intronic
ADediting_115945chr1_44279317_-intronic
ADediting_115946chr1_44279332_-intronic
ADediting_115947chr1_44279336_-intronic
ADediting_115948chr1_44279405_-intronic
ADediting_115949chr1_44279408_-intronic
ADediting_115950chr1_44279425_-intronic
ADediting_115951chr1_44279433_-intronic
ADediting_115952chr1_44279445_-intronic
ADediting_115953chr1_44279463_-intronic
ADediting_115954chr1_44279476_-intronic
ADediting_115955chr1_44279482_-intronic
ADediting_115956chr1_44279493_-intronic
ADediting_115957chr1_44279498_-intronic
ADediting_115958chr1_44279499_-intronic
ADediting_115959chr1_44279505_-intronic
ADediting_115960chr1_44281337_-intronic
ADediting_115961chr1_44281367_-intronic
ADediting_115962chr1_44281370_-intronic
ADediting_115963chr1_44281385_-intronic
ADediting_115964chr1_44281417_-intronic
ADediting_115965chr1_44281422_-intronic
ADediting_115966chr1_44281493_-intronic
ADediting_115967chr1_44281506_-intronic
ADediting_115968chr1_44281541_-intronic
ADediting_115969chr1_44281547_-intronic
ADediting_115970chr1_44299392_-intronic
ADediting_115971chr1_44299459_-intronic
ADediting_115972chr1_44299465_-intronic
ADediting_115973chr1_44299477_-intronic
ADediting_115974chr1_44309419_-intronic
ADediting_115975chr1_44309443_-intronic
ADediting_115976chr1_44341652_-intronic
ADediting_115977chr1_44341721_-intronic
ADediting_115978chr1_44341778_-intronic
ADediting_115979chr1_44341781_-intronic
ADediting_115980chr1_44341782_-intronic
ADediting_115981chr1_44341790_-intronic
ADediting_115982chr1_44341795_-intronic
ADediting_115983chr1_44341807_-intronic
ADediting_115984chr1_44341808_-intronic
ADediting_115985chr1_44341822_-intronic
ADediting_115986chr1_44341833_-intronic
ADediting_115987chr1_44341838_-intronic
ADediting_115988chr1_44342715_-intronic
ADediting_115989chr1_44342744_-intronic
ADediting_115990chr1_44342761_-intronic
ADediting_115991chr1_44342768_-intronic
ADediting_115992chr1_44342775_-intronic
ADediting_115993chr1_44342912_-intronic
ADediting_115994chr1_44342927_-intronic
ADediting_115995chr1_44342932_-intronic
ADediting_115996chr1_44342959_-intronic
ADediting_115997chr1_44342960_-intronic
ADediting_115998chr1_44342981_-intronic
ADediting_115999chr1_44342982_-intronic
ADediting_116000chr1_44344047_-intronic
ADediting_116001chr1_44344073_-intronic
ADediting_116002chr1_44344076_-intronic
ADediting_116003chr1_44344117_-intronic
ADediting_116004chr1_44344155_-intronic
ADediting_116005chr1_44344156_-intronic
ADediting_116006chr1_44344162_-intronic
ADediting_116007chr1_44344175_-intronic
ADediting_116008chr1_44349317_-intronic
ADediting_116009chr1_44349322_-intronic
ADediting_116010chr1_44349327_-intronic
ADediting_116011chr1_44350426_-intronic
ADediting_116012chr1_44350455_-intronic
ADediting_116013chr1_44350499_-intronic
ADediting_116014chr1_44350861_-intronic
ADediting_116015chr1_44351139_-intronic
ADediting_116016chr1_44351155_-intronic
ADediting_116017chr1_44351171_-intronic
ADediting_116018chr1_44351174_-intronic
ADediting_116019chr1_44351190_-intronic
ADediting_116020chr1_44351198_-intronic
ADediting_116021chr1_44351203_-intronic
ADediting_116022chr1_44351271_-intronic
ADediting_116023chr1_44351325_-intronic
ADediting_116024chr1_44352310_-intronic
ADediting_1520146chr1_44231619_-intronic
ADediting_1520147chr1_44234775_-intronic
ADediting_1520148chr1_44234779_-intronic
ADediting_1520149chr1_44234816_-intronic
ADediting_1520150chr1_44234871_-intronic
ADediting_1520151chr1_44234875_-intronic
ADediting_1520152chr1_44278644_-intronic
ADediting_1520153chr1_44278876_-intronic
ADediting_1520154chr1_44279365_-intronic
ADediting_1600950chr1_44278305_-intronic
ADediting_1600951chr1_44278308_-intronic
ADediting_1600952chr1_44278311_-intronic
ADediting_1600953chr1_44278333_-intronic
ADediting_1600954chr1_44278394_-intronic
ADediting_1600955chr1_44278420_-intronic
ADediting_1600956chr1_44278799_-intronic
ADediting_1600957chr1_44278816_-intronic
ADediting_1600958chr1_44278830_-intronic
ADediting_1600959chr1_44278875_-intronic
ADediting_1600960chr1_44292084_-intronic
ADediting_1600961chr1_44292086_-intronic
ADediting_1600962chr1_44292113_-intronic
ADediting_1600963chr1_44298652_-intronic
ADediting_1600964chr1_44309351_-intronic
ADediting_1600965chr1_44309355_-intronic
ADediting_1600966chr1_44309363_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_115913chr1_44231465_-SINEAluName=AluJo
ADediting_115914chr1_44231512_-SINEAluName=AluJo
ADediting_115915chr1_44231568_-SINEAluName=AluJo
ADediting_115916chr1_44231621_-SINEAluName=AluJo
ADediting_115917chr1_44233489_-SINEAluName=AluSc8
ADediting_115918chr1_44233501_-SINEAluName=AluSc8
ADediting_115919chr1_44233519_-SINEAluName=AluSc8
ADediting_115920chr1_44233520_-SINEAluName=AluSc8
ADediting_115921chr1_44233532_-SINEAluName=AluSc8
ADediting_115922chr1_44234537_-SINEAluName=AluSx3
ADediting_115923chr1_44234559_-SINEAluName=AluSx3
ADediting_115924chr1_44234602_-SINEAluName=AluSx3
ADediting_115925chr1_44234612_-SINEAluName=AluSx3
ADediting_115926chr1_44234617_-SINEAluName=AluSx3
ADediting_115927chr1_44234628_-SINEAluName=AluSx3
ADediting_115928chr1_44234651_-SINEAluName=AluSx3
ADediting_115929chr1_44234653_-SINEAluName=AluSx3
ADediting_115930chr1_44234806_-SINEAluName=AluSz6
ADediting_115931chr1_44234880_-SINEAluName=AluSz6
ADediting_115932chr1_44234881_-SINEAluName=AluSz6
ADediting_115934chr1_44278221_-SINEAluName=AluSz6
ADediting_115935chr1_44278233_-SINEAluName=AluSz6
ADediting_115936chr1_44278365_-SINEAluName=AluSz6
ADediting_115937chr1_44278369_-SINEAluName=AluSz6
ADediting_115938chr1_44278377_-SINEAluName=AluSz6
ADediting_115939chr1_44278415_-SINEAluName=AluSz6
ADediting_115940chr1_44278444_-SINEAluName=AluSz6
ADediting_115941chr1_44278445_-SINEAluName=AluSz6
ADediting_115942chr1_44278446_-SINEAluName=AluSz6
ADediting_115943chr1_44278639_-SINEAluName=AluSx1
ADediting_115944chr1_44279290_-SINEAluName=AluJr
ADediting_115945chr1_44279317_-SINEAluName=AluJr
ADediting_115946chr1_44279332_-SINEAluName=AluJr
ADediting_115947chr1_44279336_-SINEAluName=AluJr
ADediting_115948chr1_44279405_-SINEAluName=AluJr
ADediting_115949chr1_44279408_-SINEAluName=AluJr
ADediting_115950chr1_44279425_-SINEAluName=AluJr
ADediting_115951chr1_44279433_-SINEAluName=AluJr
ADediting_115952chr1_44279445_-SINEAluName=AluJr
ADediting_115953chr1_44279463_-SINEAluName=AluJr
ADediting_115954chr1_44279476_-SINEAluName=AluJr
ADediting_115955chr1_44279482_-SINEAluName=AluJr
ADediting_115956chr1_44279493_-SINEAluName=AluJr
ADediting_115957chr1_44279498_-SINEAluName=AluJr
ADediting_115958chr1_44279499_-SINEAluName=AluJr
ADediting_115959chr1_44279505_-SINEAluName=AluJr
ADediting_115960chr1_44281337_-SINEAluName=AluJo
ADediting_115961chr1_44281367_-SINEAluName=AluJo
ADediting_115962chr1_44281370_-SINEAluName=AluJo
ADediting_115963chr1_44281385_-SINEAluName=AluJo
ADediting_115964chr1_44281417_-SINEAluName=AluJo
ADediting_115965chr1_44281422_-SINEAluName=AluJo
ADediting_115966chr1_44281493_-SINEAluName=AluJo
ADediting_115967chr1_44281506_-SINEAluName=AluJo
ADediting_115968chr1_44281541_-SINEAluName=AluJo
ADediting_115969chr1_44281547_-SINEAluName=AluJo
ADediting_115970chr1_44299392_-SINEAluName=AluJr
ADediting_115971chr1_44299459_-SINEAluName=AluJr
ADediting_115972chr1_44299465_-SINEAluName=AluJr
ADediting_115973chr1_44299477_-SINEAluName=AluJr
ADediting_115974chr1_44309419_-SINEAluName=AluSz6
ADediting_115975chr1_44309443_-SINEAluName=AluSz6
ADediting_115976chr1_44341652_-SINEAluName=AluJo
ADediting_115977chr1_44341721_-SINEAluName=AluJo
ADediting_115978chr1_44341778_-SINEAluName=AluJo
ADediting_115979chr1_44341781_-SINEAluName=AluJo
ADediting_115980chr1_44341782_-SINEAluName=AluJo
ADediting_115981chr1_44341790_-SINEAluName=AluJo
ADediting_115982chr1_44341795_-SINEAluName=AluJo
ADediting_115983chr1_44341807_-SINEAluName=AluJo
ADediting_115984chr1_44341808_-SINEAluName=AluJo
ADediting_115985chr1_44341822_-SINEAluName=AluJo
ADediting_115986chr1_44341833_-SINEAluName=AluJo
ADediting_115987chr1_44341838_-SINEAluName=AluJo
ADediting_115988chr1_44342715_-SINEAluName=AluJo
ADediting_115989chr1_44342744_-SINEAluName=AluJo
ADediting_115990chr1_44342761_-SINEAluName=AluJo
ADediting_115991chr1_44342768_-SINEAluName=AluJo
ADediting_115992chr1_44342775_-SINEAluName=AluJo
ADediting_115993chr1_44342912_-SINEAluName=AluJo
ADediting_115994chr1_44342927_-SINEAluName=AluJo
ADediting_115995chr1_44342932_-SINEAluName=AluJo
ADediting_115996chr1_44342959_-SINEAluName=AluJo
ADediting_115997chr1_44342960_-SINEAluName=AluJo
ADediting_115998chr1_44342981_-SINEAluName=AluJo
ADediting_115999chr1_44342982_-SINEAluName=AluJo
ADediting_116000chr1_44344047_-SINEAluName=AluSz
ADediting_116001chr1_44344073_-SINEAluName=AluSz
ADediting_116002chr1_44344076_-SINEAluName=AluSz
ADediting_116003chr1_44344117_-SINEAluName=AluSz
ADediting_116004chr1_44344155_-SINEAluName=AluSz
ADediting_116005chr1_44344156_-SINEAluName=AluSz
ADediting_116006chr1_44344162_-SINEAluName=AluSz
ADediting_116007chr1_44344175_-SINEAluName=AluSz
ADediting_116008chr1_44349317_-SINEAluName=AluSx3
ADediting_116009chr1_44349322_-SINEAluName=AluSx3
ADediting_116010chr1_44349327_-SINEAluName=AluSx3
ADediting_116011chr1_44350426_-SINEAluName=AluSz6
ADediting_116012chr1_44350455_-SINEAluName=AluSz6
ADediting_116013chr1_44350499_-SINEAluName=AluSz6
ADediting_116014chr1_44350861_-SINEAluName=AluJr4
ADediting_116015chr1_44351139_-SINEAluName=AluSz
ADediting_116016chr1_44351155_-SINEAluName=AluSz
ADediting_116017chr1_44351171_-SINEAluName=AluSz
ADediting_116018chr1_44351174_-SINEAluName=AluSz
ADediting_116019chr1_44351190_-SINEAluName=AluSz
ADediting_116020chr1_44351198_-SINEAluName=AluSz
ADediting_116021chr1_44351203_-SINEAluName=AluSz
ADediting_116022chr1_44351271_-SINEAluName=AluSz
ADediting_116023chr1_44351325_-SINEAluName=AluSz
ADediting_116024chr1_44352310_-SINEAluName=FLAM_A
ADediting_1520146chr1_44231619_-SINEAluName=AluJo
ADediting_1520147chr1_44234775_-SINEAluName=AluSz6
ADediting_1520148chr1_44234779_-SINEAluName=AluSz6
ADediting_1520149chr1_44234816_-SINEAluName=AluSz6
ADediting_1520150chr1_44234871_-SINEAluName=AluSz6
ADediting_1520151chr1_44234875_-SINEAluName=AluSz6
ADediting_1520152chr1_44278644_-SINEAluName=AluSx1
ADediting_1520153chr1_44278876_-SINEAluName=AluSx1
ADediting_1520154chr1_44279365_-SINEAluName=AluJr
ADediting_1600950chr1_44278305_-SINEAluName=AluSz6
ADediting_1600951chr1_44278308_-SINEAluName=AluSz6
ADediting_1600952chr1_44278311_-SINEAluName=AluSz6
ADediting_1600953chr1_44278333_-SINEAluName=AluSz6
ADediting_1600954chr1_44278394_-SINEAluName=AluSz6
ADediting_1600955chr1_44278420_-SINEAluName=AluSz6
ADediting_1600956chr1_44278799_-SINEAluName=AluSx1
ADediting_1600957chr1_44278816_-SINEAluName=AluSx1
ADediting_1600958chr1_44278830_-SINEAluName=AluSx1
ADediting_1600959chr1_44278875_-SINEAluName=AluSx1
ADediting_1600963chr1_44298652_-SINEAluName=AluJb
ADediting_1600964chr1_44309351_-SINEAluName=AluSz6
ADediting_1600965chr1_44309355_-SINEAluName=AluSz6
ADediting_1600966chr1_44309363_-SINEAluName=AluSz6

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RNA A-to-I editing events in the alternative splicing sites for ERI3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ERI3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for ERI3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ERI3


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_496066chr15_66496985_-ENSG00000117419.16ENST00000372257.7ERI3-201hsa-miR-4512chr144221154442211618mer-1a4422115444221176153-19.89
ADediting_496066chr15_66496985_-ENSG00000117419.16ENST00000372259.9ERI3-202hsa-miR-4512chr144221154442211618mer-1a4422115444221176153-19.89
ADediting_496066chr15_66496985_-ENSG00000117419.16ENST00000456170.6ERI3-204hsa-miR-4512chr144221154442211618mer-1a4422115444221176153-19.89

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ERI3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ERI3

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_115915chr1_44231568_-0.002540643602969150.2447440857907432.38382002742799e-050.3376496581319810.004432250326782020.231124427463718
CERADediting_115919chr1_44233519_-0.007157892537385750.2187530692680112.78965791774551e-050.3349764818645890.2122187660915020.1024457207649
CERADediting_115923chr1_44234559_-0.005355616402986720.2263155488434441.84336091184673e-050.3419691463624830.0006670114685605020.274767939501743
DLPFCADediting_115925chr1_44234612_-0.4671763747701330.04144510377459880.447743844535032-0.04327323703618323.9524232249246e-080.305713631104986
CERADediting_115925chr1_44234612_-0.0199471725063290.1898827659768273.63024300310077e-050.3304420402295360.02708070096892070.18049947930183
DLPFCADediting_115926chr1_44234617_-0.797577688812070.0146255760363980.128791844485395-0.08645444233483331.19529395007926e-110.372666600670148
DLPFCADediting_115927chr1_44234628_-0.906688538646291-0.006684375388223360.171764080048343-0.07781186171979311.9094747209005e-090.332660571913329
CERADediting_115927chr1_44234628_-0.002684842275160860.2434258191767592.48236850199263e-060.3736403318659870.08681953115742980.140299650739194
DLPFCADediting_115928chr1_44234651_-0.1004094013739860.09348207817001780.965772505026418-0.002447061146451623.44259899156437e-100.346807963303433
DLPFCADediting_116004chr1_44344155_-0.2579670667892920.06444189192112570.686285531639675-0.02303002725032392.18748708412984e-090.331506843346704

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC4.22027609848008e-300.5870486374817395.568887439561e-360.6320580604520118.8683380060297e-130.391211508454174
AC5.64506870555323e-630.8234448737240263.61869541662101e-430.7316968826000941.11957545104156e-190.532094007417846
PCC1.17861136623884e-250.6640490069434922.76046599893959e-260.670394052888710.01041841220597050.184964614665326
TCX4.60198755772742e-150.5835850184854912.86872892414997e-120.5306097746692640.398580061598208-0.0694229130110229
FP2.57519173369931e-340.7567068091668712.67786441897296e-330.749085478235740.005566609547997280.20699376696645
IFG7.72102292218792e-060.767012523653692.23359672271702e-050.7413745116588910.9023486486653760.0258588407912277
PG2.52227857069139e-200.6097942059199351.47150434721251e-140.5248589794846780.475622915134699-0.0526246053921548
STG1.60668492259964e-260.8669431226270976.09126447415018e-140.7063648724188380.1355146631234440.164220100223567

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Relation with AD stages for ERI3

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
IFGADediting_115937chr1_44278369_-0.03547133699799280.422303326441651
IFGADediting_115938chr1_44278377_-0.03547133699799280.422303326441651

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.

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RelatedDrugs for ERI3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ERI3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource