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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for CACNB1

check button Gene summary
Gene informationGene symbol

CACNB1

Gene ID

782

Gene namecalcium voltage-gated channel auxiliary subunit beta 1
SynonymsCAB1|CACNLB1|CCHLB1
Cytomap

17q12

Type of geneprotein-coding
Descriptionvoltage-dependent L-type calcium channel subunit beta-1calcium channel voltage-dependent subunit beta 1calcium channel, L type, beta 1 polypeptidecalcium channel, voltage-dependent, beta 1 subunitdihydropyridine-sensitive L-type, calcium channel beta-
Modification date20200313
UniProtAcc

Q02641,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for CACNB1

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_615571(39178449, -), ADediting_615572(39178451, -), ADediting_615573(39178457, -), ADediting_615574(39178460, -), ADediting_615575(39178468, -), ADediting_615576(39178496, -), ADediting_615577(39178504, -), ADediting_615578(39178518, -), ADediting_615579(39178528, -), ADediting_615580(39178533, -), ADediting_615581(39178536, -), ADediting_615582(39178544, -), ADediting_615583(39178548, -), ADediting_615584(39178559, -), ADediting_615585(39178578, -), ADediting_615586(39178579, -), ADediting_615587(39178581, -), ADediting_615588(39178582, -), ADediting_615589(39178586, -), ADediting_615590(39178596, -), ADediting_615591(39178610, -), ADediting_615592(39178628, -), ADediting_615593(39178629, -), ADediting_615594(39178641, -), ADediting_615595(39178650, -), ADediting_615596(39178655, -), ADediting_615597(39178656, -), ADediting_615598(39178658, -), ADediting_615599(39178664, -), ADediting_615600(39178672, -), ADediting_615601(39179049, -), ADediting_615602(39179074, -), ADediting_615603(39179104, -), ADediting_615604(39179109, -), ADediting_615605(39179126, -), ADediting_615606(39179129, -), ADediting_615607(39179171, -), ADediting_615608(39179176, -), ADediting_615609(39179181, -), ADediting_615610(39179184, -), ADediting_615611(39179254, -), ADediting_615612(39179359, -), ADediting_615613(39179421, -), ADediting_615614(39179424, -), ADediting_615615(39179453, -), ADediting_615616(39179459, -), ADediting_615617(39179469, -), ADediting_615618(39179505, -), ADediting_615619(39179529, -), ADediting_615620(39179565, -), ADediting_615621(39179651, -), ADediting_615622(39179682, -), ADediting_615623(39179716, -), ADediting_615624(39179787, -), ADediting_615625(39179797, -), ADediting_615626(39179832, -), ADediting_615627(39179833, -), ADediting_615628(39179857, -), ADediting_615629(39180006, -), ADediting_615630(39180018, -), ADediting_615631(39180019, -), ADediting_615632(39180020, -), ADediting_615633(39180033, -), ADediting_615634(39180048, -), ADediting_615635(39180082, -), ADediting_615636(39180099, -), ADediting_615637(39180125, -), ADediting_615638(39180143, -), ADediting_615639(39180153, -), ADediting_615640(39180165, -), ADediting_615641(39180176, -), ADediting_615642(39180179, -), ADediting_615643(39180185, -), ADediting_615644(39180200, -), ADediting_615645(39180205, -), ADediting_615646(39180249, -), ADediting_615647(39180398, -), ADediting_615648(39180410, -), ADediting_615649(39180411, -), ADediting_615650(39180420, -), ADediting_615651(39180435, -), ADediting_615652(39180436, -), ADediting_615653(39180489, -), ADediting_615654(39180492, -), ADediting_615655(39180531, -), ADediting_615656(39180533, -), ADediting_615657(39180543, -), ADediting_615658(39180546, -), ADediting_615659(39180547, -), ADediting_615660(39180568, -), ADediting_615661(39180572, -), ADediting_615662(39180573, -), ADediting_615663(39180579, -), ADediting_615664(39180648, -), ADediting_615665(39180805, -), ADediting_615666(39180815, -), ADediting_615667(39180845, -), ADediting_615668(39180850, -), ADediting_615669(39180851, -), ADediting_615670(39180857, -), ADediting_615671(39180873, -), ADediting_615672(39180877, -), ADediting_615673(39181123, -), ADediting_615674(39181124, -), ADediting_615675(39181141, -), ADediting_615676(39181146, -), ADediting_615677(39181161, -), ADediting_615678(39181166, -), ADediting_615679(39181190, -), ADediting_615680(39181218, -), ADediting_615681(39181222, -), ADediting_615682(39181231, -), ADediting_615683(39181232, -), ADediting_615684(39181238, -), ADediting_615685(39181250, -), ADediting_615686(39181258, -), ADediting_615687(39181262, -), ADediting_615688(39181263, -), ADediting_615689(39181271, -), ADediting_615690(39181272, -), ADediting_615691(39181273, -), ADediting_615692(39181276, -), ADediting_615693(39181287, -), ADediting_615694(39181292, -), ADediting_615695(39181295, -), ADediting_615696(39181297, -), ADediting_615697(39181307, -), ADediting_615698(39181312, -), ADediting_615699(39181313, -), ADediting_615700(39181320, -), ADediting_615701(39181358, -), ADediting_615702(39181366, -), ADediting_615703(39181367, -), ADediting_615704(39181373, -), ADediting_615705(39181385, -), ADediting_615706(39181389, -), ADediting_615707(39181760, -), ADediting_615708(39181772, -), ADediting_615709(39181773, -), ADediting_615710(39181782, -), ADediting_615711(39181800, -), ADediting_615712(39181813, -), ADediting_615713(39181815, -), ADediting_615714(39181849, -), ADediting_615715(39181852, -), ADediting_615716(39181912, -), ADediting_615717(39181918, -), ADediting_615718(39181978, -), ADediting_615719(39181995, -), ADediting_615720(39181998, -), ADediting_615721(39182039, -), ADediting_615722(39182049, -), ADediting_615723(39182146, -), ADediting_615724(39182245, -), ADediting_615725(39182252, -), ADediting_615726(39182268, -), ADediting_615727(39182444, -), ADediting_615728(39182456, -), ADediting_615729(39182457, -), ADediting_615730(39182471, -), ADediting_615731(39182516, -), ADediting_615732(39182533, -), ADediting_615733(39182536, -), ADediting_615734(39182552, -), ADediting_615735(39182553, -), ADediting_615736(39182580, -), ADediting_615737(39182602, -), ADediting_615738(39182619, -), ADediting_615739(39182620, -), ADediting_615740(39182626, -), ADediting_615741(39182639, -), ADediting_615742(39182640, -), ADediting_615743(39182645, -), ADediting_615744(39183168, -), ADediting_615745(39183210, -), ADediting_615746(39183220, -), ADediting_615747(39183237, -), ADediting_615748(39183245, -), ADediting_615749(39183246, -), ADediting_615750(39183250, -), ADediting_615751(39183251, -), ADediting_615752(39183270, -), ADediting_615753(39183285, -), ADediting_615754(39187851, -), ADediting_615755(39188856, -), ADediting_615756(39188872, -), ADediting_615757(39188921, -), ADediting_615758(39189319, -), ADediting_615759(39189537, -), ADediting_615760(39189659, -), ADediting_615761(39189671, -), ADediting_615762(39189691, -), ADediting_615763(39189701, -), ADediting_615764(39189770, -), ADediting_615765(39189771, -), ADediting_615766(39189847, -), ADediting_615767(39189855, -), ADediting_615768(39189867, -), ADediting_615769(39189868, -), ADediting_615770(39190003, -), ADediting_615771(39190080, -), ADediting_615772(39190520, -), ADediting_615773(39190556, -), ADediting_615774(39190565, -), ADediting_615775(39190566, -), ADediting_615776(39190621, -), ADediting_615777(39194167, -), ADediting_1546249(39178584, -), ADediting_1546250(39179050, -), ADediting_1546251(39179865, -), ADediting_1546252(39180102, -), ADediting_1546253(39181321, -), ADediting_1546254(39181855, -), ADediting_1546255(39182426, -),

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RNA editing positional annotations for CACNB1 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_615571chr17_39178449_-intronic
ADediting_615572chr17_39178451_-intronic
ADediting_615573chr17_39178457_-intronic
ADediting_615574chr17_39178460_-intronic
ADediting_615575chr17_39178468_-intronic
ADediting_615576chr17_39178496_-intronic
ADediting_615577chr17_39178504_-intronic
ADediting_615578chr17_39178518_-intronic
ADediting_615579chr17_39178528_-intronic
ADediting_615580chr17_39178533_-intronic
ADediting_615581chr17_39178536_-intronic
ADediting_615582chr17_39178544_-intronic
ADediting_615583chr17_39178548_-intronic
ADediting_615584chr17_39178559_-intronic
ADediting_615585chr17_39178578_-intronic
ADediting_615586chr17_39178579_-intronic
ADediting_615587chr17_39178581_-intronic
ADediting_615588chr17_39178582_-intronic
ADediting_615589chr17_39178586_-intronic
ADediting_615590chr17_39178596_-intronic
ADediting_615591chr17_39178610_-intronic
ADediting_615592chr17_39178628_-intronic
ADediting_615593chr17_39178629_-intronic
ADediting_615594chr17_39178641_-intronic
ADediting_615595chr17_39178650_-intronic
ADediting_615596chr17_39178655_-intronic
ADediting_615597chr17_39178656_-intronic
ADediting_615598chr17_39178658_-intronic
ADediting_615599chr17_39178664_-intronic
ADediting_615600chr17_39178672_-intronic
ADediting_615601chr17_39179049_-intronic
ADediting_615602chr17_39179074_-intronic
ADediting_615603chr17_39179104_-intronic
ADediting_615604chr17_39179109_-intronic
ADediting_615605chr17_39179126_-intronic
ADediting_615606chr17_39179129_-intronic
ADediting_615607chr17_39179171_-intronic
ADediting_615608chr17_39179176_-intronic
ADediting_615609chr17_39179181_-intronic
ADediting_615610chr17_39179184_-intronic
ADediting_615611chr17_39179254_-intronic
ADediting_615612chr17_39179359_-intronic
ADediting_615613chr17_39179421_-intronic
ADediting_615614chr17_39179424_-intronic
ADediting_615615chr17_39179453_-intronic
ADediting_615616chr17_39179459_-intronic
ADediting_615617chr17_39179469_-intronic
ADediting_615618chr17_39179505_-intronic
ADediting_615619chr17_39179529_-intronic
ADediting_615620chr17_39179565_-intronic
ADediting_615621chr17_39179651_-intronic
ADediting_615622chr17_39179682_-intronic
ADediting_615623chr17_39179716_-intronic
ADediting_615624chr17_39179787_-intronic
ADediting_615625chr17_39179797_-intronic
ADediting_615626chr17_39179832_-intronic
ADediting_615627chr17_39179833_-intronic
ADediting_615628chr17_39179857_-intronic
ADediting_615629chr17_39180006_-intronic
ADediting_615630chr17_39180018_-intronic
ADediting_615631chr17_39180019_-intronic
ADediting_615632chr17_39180020_-intronic
ADediting_615633chr17_39180033_-intronic
ADediting_615634chr17_39180048_-intronic
ADediting_615635chr17_39180082_-intronic
ADediting_615636chr17_39180099_-intronic
ADediting_615637chr17_39180125_-intronic
ADediting_615638chr17_39180143_-intronic
ADediting_615639chr17_39180153_-intronic
ADediting_615640chr17_39180165_-intronic
ADediting_615641chr17_39180176_-intronic
ADediting_615642chr17_39180179_-intronic
ADediting_615643chr17_39180185_-intronic
ADediting_615644chr17_39180200_-intronic
ADediting_615645chr17_39180205_-intronic
ADediting_615646chr17_39180249_-intronic
ADediting_615647chr17_39180398_-intronic
ADediting_615648chr17_39180410_-intronic
ADediting_615649chr17_39180411_-intronic
ADediting_615650chr17_39180420_-intronic
ADediting_615651chr17_39180435_-intronic
ADediting_615652chr17_39180436_-intronic
ADediting_615653chr17_39180489_-intronic
ADediting_615654chr17_39180492_-intronic
ADediting_615655chr17_39180531_-intronic
ADediting_615656chr17_39180533_-intronic
ADediting_615657chr17_39180543_-intronic
ADediting_615658chr17_39180546_-intronic
ADediting_615659chr17_39180547_-intronic
ADediting_615660chr17_39180568_-intronic
ADediting_615661chr17_39180572_-intronic
ADediting_615662chr17_39180573_-intronic
ADediting_615663chr17_39180579_-intronic
ADediting_615664chr17_39180648_-intronic
ADediting_615665chr17_39180805_-intronic
ADediting_615666chr17_39180815_-intronic
ADediting_615667chr17_39180845_-intronic
ADediting_615668chr17_39180850_-intronic
ADediting_615669chr17_39180851_-intronic
ADediting_615670chr17_39180857_-intronic
ADediting_615671chr17_39180873_-intronic
ADediting_615672chr17_39180877_-intronic
ADediting_615673chr17_39181123_-intronic
ADediting_615674chr17_39181124_-intronic
ADediting_615675chr17_39181141_-intronic
ADediting_615676chr17_39181146_-intronic
ADediting_615677chr17_39181161_-intronic
ADediting_615678chr17_39181166_-intronic
ADediting_615679chr17_39181190_-intronic
ADediting_615680chr17_39181218_-intronic
ADediting_615681chr17_39181222_-intronic
ADediting_615682chr17_39181231_-intronic
ADediting_615683chr17_39181232_-intronic
ADediting_615684chr17_39181238_-intronic
ADediting_615685chr17_39181250_-intronic
ADediting_615686chr17_39181258_-intronic
ADediting_615687chr17_39181262_-intronic
ADediting_615688chr17_39181263_-intronic
ADediting_615689chr17_39181271_-intronic
ADediting_615690chr17_39181272_-intronic
ADediting_615691chr17_39181273_-intronic
ADediting_615692chr17_39181276_-intronic
ADediting_615693chr17_39181287_-intronic
ADediting_615694chr17_39181292_-intronic
ADediting_615695chr17_39181295_-intronic
ADediting_615696chr17_39181297_-intronic
ADediting_615697chr17_39181307_-intronic
ADediting_615698chr17_39181312_-intronic
ADediting_615699chr17_39181313_-intronic
ADediting_615700chr17_39181320_-intronic
ADediting_615701chr17_39181358_-intronic
ADediting_615702chr17_39181366_-intronic
ADediting_615703chr17_39181367_-intronic
ADediting_615704chr17_39181373_-intronic
ADediting_615705chr17_39181385_-intronic
ADediting_615706chr17_39181389_-intronic
ADediting_615707chr17_39181760_-intronic
ADediting_615708chr17_39181772_-intronic
ADediting_615709chr17_39181773_-intronic
ADediting_615710chr17_39181782_-intronic
ADediting_615711chr17_39181800_-intronic
ADediting_615712chr17_39181813_-intronic
ADediting_615713chr17_39181815_-intronic
ADediting_615714chr17_39181849_-intronic
ADediting_615715chr17_39181852_-intronic
ADediting_615716chr17_39181912_-intronic
ADediting_615717chr17_39181918_-intronic
ADediting_615718chr17_39181978_-intronic
ADediting_615719chr17_39181995_-intronic
ADediting_615720chr17_39181998_-intronic
ADediting_615721chr17_39182039_-intronic
ADediting_615722chr17_39182049_-intronic
ADediting_615723chr17_39182146_-intronic
ADediting_615724chr17_39182245_-intronic
ADediting_615725chr17_39182252_-intronic
ADediting_615726chr17_39182268_-intronic
ADediting_615727chr17_39182444_-intronic
ADediting_615728chr17_39182456_-intronic
ADediting_615729chr17_39182457_-intronic
ADediting_615730chr17_39182471_-intronic
ADediting_615731chr17_39182516_-intronic
ADediting_615732chr17_39182533_-intronic
ADediting_615733chr17_39182536_-intronic
ADediting_615734chr17_39182552_-intronic
ADediting_615735chr17_39182553_-intronic
ADediting_615736chr17_39182580_-intronic
ADediting_615737chr17_39182602_-intronic
ADediting_615738chr17_39182619_-intronic
ADediting_615739chr17_39182620_-intronic
ADediting_615740chr17_39182626_-intronic
ADediting_615741chr17_39182639_-intronic
ADediting_615742chr17_39182640_-intronic
ADediting_615743chr17_39182645_-intronic
ADediting_615744chr17_39183168_-intronic
ADediting_615745chr17_39183210_-intronic
ADediting_615746chr17_39183220_-intronic
ADediting_615747chr17_39183237_-intronic
ADediting_615748chr17_39183245_-intronic
ADediting_615749chr17_39183246_-intronic
ADediting_615750chr17_39183250_-intronic
ADediting_615751chr17_39183251_-intronic
ADediting_615752chr17_39183270_-intronic
ADediting_615753chr17_39183285_-intronic
ADediting_615754chr17_39187851_-intronic
ADediting_615755chr17_39188856_-intronic
ADediting_615756chr17_39188872_-intronic
ADediting_615757chr17_39188921_-intronic
ADediting_615758chr17_39189319_-intronic
ADediting_615759chr17_39189537_-intronic
ADediting_615760chr17_39189659_-intronic
ADediting_615761chr17_39189671_-intronic
ADediting_615762chr17_39189691_-intronic
ADediting_615763chr17_39189701_-intronic
ADediting_615764chr17_39189770_-intronic
ADediting_615765chr17_39189771_-intronic
ADediting_615766chr17_39189847_-intronic
ADediting_615767chr17_39189855_-intronic
ADediting_615768chr17_39189867_-intronic
ADediting_615769chr17_39189868_-intronic
ADediting_615770chr17_39190003_-intronic
ADediting_615771chr17_39190080_-intronic
ADediting_615772chr17_39190520_-intronic
ADediting_615773chr17_39190556_-intronic
ADediting_615774chr17_39190565_-intronic
ADediting_615775chr17_39190566_-intronic
ADediting_615776chr17_39190621_-intronic
ADediting_615777chr17_39194167_-intronic
ADediting_1546249chr17_39178584_-intronic
ADediting_1546250chr17_39179050_-intronic
ADediting_1546251chr17_39179865_-intronic
ADediting_1546252chr17_39180102_-intronic
ADediting_1546253chr17_39181321_-intronic
ADediting_1546254chr17_39181855_-intronic
ADediting_1546255chr17_39182426_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_615571chr17_39178449_-SINEAluName=AluJr4
ADediting_615572chr17_39178451_-SINEAluName=AluJr4
ADediting_615573chr17_39178457_-SINEAluName=AluJr4
ADediting_615574chr17_39178460_-SINEAluName=AluJr4
ADediting_615575chr17_39178468_-SINEAluName=AluJr4
ADediting_615576chr17_39178496_-SINEAluName=AluJr4
ADediting_615577chr17_39178504_-SINEAluName=AluJr4
ADediting_615578chr17_39178518_-SINEAluName=AluJr4
ADediting_615579chr17_39178528_-SINEAluName=AluJr4
ADediting_615580chr17_39178533_-SINEAluName=AluJr4
ADediting_615581chr17_39178536_-SINEAluName=AluJr4
ADediting_615582chr17_39178544_-SINEAluName=AluJr4
ADediting_615583chr17_39178548_-SINEAluName=AluJr4
ADediting_615584chr17_39178559_-SINEAluName=AluJr4
ADediting_615585chr17_39178578_-SINEAluName=AluJr4
ADediting_615586chr17_39178579_-SINEAluName=AluJr4
ADediting_615587chr17_39178581_-SINEAluName=AluJr4
ADediting_615588chr17_39178582_-SINEAluName=AluJr4
ADediting_615589chr17_39178586_-SINEAluName=AluJr4
ADediting_615590chr17_39178596_-SINEAluName=AluJr4
ADediting_615591chr17_39178610_-SINEAluName=AluJr4
ADediting_615592chr17_39178628_-SINEAluName=AluJr4
ADediting_615593chr17_39178629_-SINEAluName=AluJr4
ADediting_615594chr17_39178641_-SINEAluName=AluJr4
ADediting_615595chr17_39178650_-SINEAluName=AluJr4
ADediting_615596chr17_39178655_-SINEAluName=AluJr4
ADediting_615597chr17_39178656_-SINEAluName=AluJr4
ADediting_615598chr17_39178658_-SINEAluName=AluJr4
ADediting_615599chr17_39178664_-SINEAluName=AluJr4
ADediting_615600chr17_39178672_-SINEAluName=AluJr4
ADediting_615601chr17_39179049_-SINEAluName=AluY
ADediting_615602chr17_39179074_-SINEAluName=AluY
ADediting_615603chr17_39179104_-SINEAluName=AluY
ADediting_615604chr17_39179109_-SINEAluName=AluY
ADediting_615605chr17_39179126_-SINEAluName=AluY
ADediting_615606chr17_39179129_-SINEAluName=AluY
ADediting_615607chr17_39179171_-SINEAluName=AluY
ADediting_615608chr17_39179176_-SINEAluName=AluY
ADediting_615609chr17_39179181_-SINEAluName=AluY
ADediting_615610chr17_39179184_-SINEAluName=AluY
ADediting_615611chr17_39179254_-SINEAluName=AluY
ADediting_615612chr17_39179359_-SINEAluName=AluY
ADediting_615613chr17_39179421_-SINEAluName=AluY
ADediting_615614chr17_39179424_-SINEAluName=AluY
ADediting_615615chr17_39179453_-SINEAluName=AluY
ADediting_615616chr17_39179459_-SINEAluName=AluY
ADediting_615617chr17_39179469_-SINEAluName=AluY
ADediting_615618chr17_39179505_-SINEAluName=AluY
ADediting_615619chr17_39179529_-SINEAluName=AluY
ADediting_615620chr17_39179565_-SINEAluName=AluY
ADediting_615621chr17_39179651_-SINEAluName=AluSx
ADediting_615622chr17_39179682_-SINEAluName=AluSx
ADediting_615623chr17_39179716_-SINEAluName=AluSx
ADediting_615624chr17_39179787_-SINEAluName=AluSx
ADediting_615625chr17_39179797_-SINEAluName=AluSx
ADediting_615626chr17_39179832_-SINEAluName=AluSx
ADediting_615627chr17_39179833_-SINEAluName=AluSx
ADediting_615628chr17_39179857_-SINEAluName=AluSx
ADediting_615629chr17_39180006_-SINEAluName=AluSq
ADediting_615630chr17_39180018_-SINEAluName=AluSq
ADediting_615631chr17_39180019_-SINEAluName=AluSq
ADediting_615632chr17_39180020_-SINEAluName=AluSq
ADediting_615633chr17_39180033_-SINEAluName=AluSq
ADediting_615634chr17_39180048_-SINEAluName=AluSq
ADediting_615635chr17_39180082_-SINEAluName=AluSq
ADediting_615636chr17_39180099_-SINEAluName=AluSq
ADediting_615637chr17_39180125_-SINEAluName=AluSq
ADediting_615638chr17_39180143_-SINEAluName=AluSq
ADediting_615639chr17_39180153_-SINEAluName=AluSq
ADediting_615640chr17_39180165_-SINEAluName=AluSq
ADediting_615641chr17_39180176_-SINEAluName=AluSq
ADediting_615642chr17_39180179_-SINEAluName=AluSq
ADediting_615643chr17_39180185_-SINEAluName=AluSq
ADediting_615644chr17_39180200_-SINEAluName=AluSq
ADediting_615645chr17_39180205_-SINEAluName=AluSq
ADediting_615646chr17_39180249_-SINEAluName=AluSq
ADediting_615647chr17_39180398_-SINEAluName=AluSx1
ADediting_615648chr17_39180410_-SINEAluName=AluSx1
ADediting_615649chr17_39180411_-SINEAluName=AluSx1
ADediting_615650chr17_39180420_-SINEAluName=AluSx1
ADediting_615651chr17_39180435_-SINEAluName=AluSx1
ADediting_615652chr17_39180436_-SINEAluName=AluSx1
ADediting_615653chr17_39180489_-SINEAluName=AluSx1
ADediting_615654chr17_39180492_-SINEAluName=AluSx1
ADediting_615655chr17_39180531_-SINEAluName=AluSx1
ADediting_615656chr17_39180533_-SINEAluName=AluSx1
ADediting_615657chr17_39180543_-SINEAluName=AluSx1
ADediting_615658chr17_39180546_-SINEAluName=AluSx1
ADediting_615659chr17_39180547_-SINEAluName=AluSx1
ADediting_615660chr17_39180568_-SINEAluName=AluSx1
ADediting_615661chr17_39180572_-SINEAluName=AluSx1
ADediting_615662chr17_39180573_-SINEAluName=AluSx1
ADediting_615663chr17_39180579_-SINEAluName=AluSx1
ADediting_615664chr17_39180648_-SINEAluName=AluSx1
ADediting_615665chr17_39180805_-SINEAluName=AluSz6
ADediting_615666chr17_39180815_-SINEAluName=AluSz6
ADediting_615667chr17_39180845_-SINEAluName=AluSz6
ADediting_615668chr17_39180850_-SINEAluName=AluSz6
ADediting_615669chr17_39180851_-SINEAluName=AluSz6
ADediting_615670chr17_39180857_-SINEAluName=AluSz6
ADediting_615671chr17_39180873_-SINEAluName=AluSz6
ADediting_615672chr17_39180877_-LINEL1Name=L1MC4
ADediting_615673chr17_39181123_-SINEAluName=AluSx1
ADediting_615674chr17_39181124_-SINEAluName=AluSx1
ADediting_615675chr17_39181141_-SINEAluName=AluSx1
ADediting_615676chr17_39181146_-SINEAluName=AluSx1
ADediting_615677chr17_39181161_-SINEAluName=AluSx1
ADediting_615678chr17_39181166_-SINEAluName=AluSx1
ADediting_615679chr17_39181190_-SINEAluName=AluSx1
ADediting_615680chr17_39181218_-SINEAluName=AluSx1
ADediting_615681chr17_39181222_-SINEAluName=AluSx1
ADediting_615682chr17_39181231_-SINEAluName=AluSx1
ADediting_615683chr17_39181232_-SINEAluName=AluSx1
ADediting_615684chr17_39181238_-SINEAluName=AluSx1
ADediting_615685chr17_39181250_-SINEAluName=AluSx1
ADediting_615686chr17_39181258_-SINEAluName=AluSx1
ADediting_615687chr17_39181262_-SINEAluName=AluSx1
ADediting_615688chr17_39181263_-SINEAluName=AluSx1
ADediting_615689chr17_39181271_-SINEAluName=AluSx1
ADediting_615690chr17_39181272_-SINEAluName=AluSx1
ADediting_615691chr17_39181273_-SINEAluName=AluSx1
ADediting_615692chr17_39181276_-SINEAluName=AluSx1
ADediting_615693chr17_39181287_-SINEAluName=AluSx1
ADediting_615694chr17_39181292_-SINEAluName=AluSx1
ADediting_615695chr17_39181295_-SINEAluName=AluSx1
ADediting_615696chr17_39181297_-SINEAluName=AluSx1
ADediting_615697chr17_39181307_-SINEAluName=AluSx1
ADediting_615698chr17_39181312_-SINEAluName=AluSx1
ADediting_615699chr17_39181313_-SINEAluName=AluSx1
ADediting_615700chr17_39181320_-SINEAluName=AluSx1
ADediting_615701chr17_39181358_-SINEAluName=AluSx1
ADediting_615702chr17_39181366_-SINEAluName=AluSx1
ADediting_615703chr17_39181367_-SINEAluName=AluSx1
ADediting_615704chr17_39181373_-SINEAluName=AluSx1
ADediting_615705chr17_39181385_-SINEAluName=AluSx1
ADediting_615706chr17_39181389_-SINEAluName=AluSx1
ADediting_615707chr17_39181760_-SINEAluName=AluSz
ADediting_615708chr17_39181772_-SINEAluName=AluSz
ADediting_615709chr17_39181773_-SINEAluName=AluSz
ADediting_615710chr17_39181782_-SINEAluName=AluSz
ADediting_615711chr17_39181800_-SINEAluName=AluSz
ADediting_615712chr17_39181813_-SINEAluName=AluSz
ADediting_615713chr17_39181815_-SINEAluName=AluSz
ADediting_615714chr17_39181849_-SINEAluName=AluSz
ADediting_615715chr17_39181852_-SINEAluName=AluSz
ADediting_615716chr17_39181912_-SINEAluName=AluSx4
ADediting_615717chr17_39181918_-SINEAluName=AluSx4
ADediting_615718chr17_39181978_-SINEAluName=AluSx4
ADediting_615719chr17_39181995_-SINEAluName=AluSx4
ADediting_615720chr17_39181998_-SINEAluName=AluSx4
ADediting_615721chr17_39182039_-SINEAluName=AluSx4
ADediting_615722chr17_39182049_-SINEAluName=AluSx4
ADediting_615723chr17_39182146_-SINEAluName=AluSx4
ADediting_615724chr17_39182245_-SINEAluName=AluSz
ADediting_615725chr17_39182252_-SINEAluName=AluSz
ADediting_615726chr17_39182268_-SINEAluName=AluSz
ADediting_615727chr17_39182444_-SINEAluName=AluSc8
ADediting_615728chr17_39182456_-SINEAluName=AluSc8
ADediting_615729chr17_39182457_-SINEAluName=AluSc8
ADediting_615730chr17_39182471_-SINEAluName=AluSc8
ADediting_615731chr17_39182516_-SINEAluName=AluSc8
ADediting_615732chr17_39182533_-SINEAluName=AluSc8
ADediting_615733chr17_39182536_-SINEAluName=AluSc8
ADediting_615734chr17_39182552_-SINEAluName=AluSc8
ADediting_615735chr17_39182553_-SINEAluName=AluSc8
ADediting_615736chr17_39182580_-SINEAluName=AluSc8
ADediting_615737chr17_39182602_-SINEAluName=AluSc8
ADediting_615738chr17_39182619_-SINEAluName=AluSc8
ADediting_615739chr17_39182620_-SINEAluName=AluSc8
ADediting_615740chr17_39182626_-SINEAluName=AluSc8
ADediting_615741chr17_39182639_-SINEAluName=AluSc8
ADediting_615742chr17_39182640_-SINEAluName=AluSc8
ADediting_615743chr17_39182645_-SINEAluName=AluSc8
ADediting_615744chr17_39183168_-SINEAluName=AluJr
ADediting_615745chr17_39183210_-SINEAluName=AluJr
ADediting_615746chr17_39183220_-SINEAluName=AluJr
ADediting_615747chr17_39183237_-SINEAluName=AluJr
ADediting_615748chr17_39183245_-SINEAluName=AluJr
ADediting_615749chr17_39183246_-SINEAluName=AluJr
ADediting_615750chr17_39183250_-SINEAluName=AluJr
ADediting_615751chr17_39183251_-SINEAluName=AluJr
ADediting_615752chr17_39183270_-SINEAluName=AluJr
ADediting_615753chr17_39183285_-SINEAluName=AluJr
ADediting_615754chr17_39187851_-SINEAluName=AluSx1
ADediting_615755chr17_39188856_-SINEAluName=AluSq
ADediting_615756chr17_39188872_-SINEAluName=AluSq
ADediting_615757chr17_39188921_-SINEAluName=AluSq
ADediting_615758chr17_39189319_-SINEAluName=AluSg
ADediting_615759chr17_39189537_-SINEAluName=AluSp
ADediting_615760chr17_39189659_-SINEAluName=AluSp
ADediting_615761chr17_39189671_-SINEAluName=AluSp
ADediting_615762chr17_39189691_-SINEAluName=AluSp
ADediting_615763chr17_39189701_-SINEAluName=AluSp
ADediting_615764chr17_39189770_-SINEAluName=AluSp
ADediting_615765chr17_39189771_-SINEAluName=AluSp
ADediting_615766chr17_39189847_-SINEAluName=AluSx1
ADediting_615767chr17_39189855_-SINEAluName=AluSx1
ADediting_615768chr17_39189867_-SINEAluName=AluSx1
ADediting_615769chr17_39189868_-SINEAluName=AluSx1
ADediting_615770chr17_39190003_-SINEAluName=AluSx1
ADediting_615771chr17_39190080_-SINEAluName=AluSx1
ADediting_615772chr17_39190520_-SINEAluName=AluSz
ADediting_615773chr17_39190556_-SINEAluName=AluSz
ADediting_615774chr17_39190565_-SINEAluName=AluSz
ADediting_615775chr17_39190566_-SINEAluName=AluSz
ADediting_615776chr17_39190621_-SINEAluName=AluSz
ADediting_1546249chr17_39178584_-SINEAluName=AluJr4
ADediting_1546250chr17_39179050_-SINEAluName=AluY
ADediting_1546251chr17_39179865_-SINEAluName=AluSx
ADediting_1546252chr17_39180102_-SINEAluName=AluSq
ADediting_1546253chr17_39181321_-SINEAluName=AluSx1
ADediting_1546254chr17_39181855_-SINEAluName=AluSz
ADediting_1546255chr17_39182426_-SINEAluName=AluSc8

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RNA A-to-I editing events in the alternative splicing sites for CACNB1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CACNB1

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for CACNB1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CACNB1


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000067191.16ENST00000344140.5CACNB1-201hsa-miR-589-3pchr1739177213391772197mer-m83917721239177235140-14.9
ADediting_1337757chr7_5495852_-ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-589-3pchr1739174221391742277mer-m83917422039174245157-20.96
ADediting_1337757chr7_5495852_-ENSG00000067191.16ENST00000394310.7CACNB1-203hsa-miR-589-3pchr1739177213391772197mer-m83917721239177235140-14.9
ADediting_1337757chr7_5495852_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-589-3pchr1739174221391742277mer-m83917422039174245157-20.96
ADediting_1391023chr8_140732605_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-151a-3pchr1739178036391780438mer-1a3917803639178058161-25.31
ADediting_496066chr15_66496985_-ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-4512chr1739174310391743178mer-1a3917431039174331154-20.87
ADediting_496066chr15_66496985_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-4512chr1739174310391743178mer-1a3917431039174331154-20.87

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_107020chr1_37500952_-ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-5581-3pchr1739174653391746597mer-m83917465239174673140-10.89
ADediting_107020chr1_37500952_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-5581-3pchr1739174653391746597mer-m83917465239174673140-10.89
ADediting_1097295chr3_85385762_+ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-5688chr1739174193391742008mer-1a3917419339174214145-11.14
ADediting_1097295chr3_85385762_+ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-5688chr1739174193391742008mer-1a3917419339174214145-11.14
ADediting_1471003chr9_63819626_+ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-4477bchr1739174882391748887mer-m83917488139174902143-8.99
ADediting_1471003chr9_63819626_+ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-4477bchr1739174882391748887mer-m83917488139174902143-8.99
ADediting_1471004chr9_63819627_+ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-4477bchr1739174882391748887mer-m83917488139174902143-8.99
ADediting_1471004chr9_63819627_+ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-4477bchr1739174882391748887mer-m83917488139174902143-8.99
ADediting_1556067chr19_40282625_-ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-641chr1739173476391734838mer-1a3917347639173498148-12.27
ADediting_1556067chr19_40282625_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-641chr1739173476391734838mer-1a3917347639173498148-12.27
ADediting_1631458chr19_40282624_-ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-641chr1739173476391734838mer-1a3917347639173498148-12.27
ADediting_1631458chr19_40282624_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-641chr1739173476391734838mer-1a3917347639173498148-12.27
ADediting_496066chr15_66496985_-ENSG00000067191.16ENST00000394303.8CACNB1-202hsa-miR-4512chr1739175017391750237mer-m83917501639175037153-20.46
ADediting_496066chr15_66496985_-ENSG00000067191.16ENST00000622445.4CACNB1-212hsa-miR-4512chr1739175017391750237mer-m83917501639175037153-20.46

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CACNB1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CACNB1

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_615586chr17_39178579_-0.1098736873590410.09098265797350310.428359231498877-0.04514214508876625.08841653918918e-200.488765815353617
DLPFCADediting_615587chr17_39178581_-0.473304019076880.04087742209971540.743333784825357-0.01867124829480061.10930092741444e-100.355785493430609
DLPFCADediting_615591chr17_39178610_-0.640165203544874-0.02665334414589270.028149790724884-0.1246952938526096.4385852265853e-130.39341562885363
DLPFCADediting_615630chr17_39180018_-0.0005176083647016740.1960418703302110.007111638235783110.1525911594682794.13740237830582e-100.345323454727135
DLPFCADediting_615644chr17_39180200_-0.007155396839009680.1524764857546830.4374405451666890.04426069863849653.35703996158147e-190.479173021537507
DLPFCADediting_615648chr17_39180410_-3.54663576315839e-050.2325740048451680.008711626676556320.1487570591230297.91144621459847e-120.375688260055365
DLPFCADediting_615650chr17_39180420_-0.005132129710876460.1585845788803090.05279450983284390.1101015405768528.76326774214667e-130.391293850915966
DLPFCADediting_615652chr17_39180436_-0.1559430538472840.08077978827623120.630710121454984-0.02740908792199249.5707750447935e-150.420968204330763
DLPFCADediting_615656chr17_39180533_-0.01159009553627920.1432141631175280.8240885301429880.01267589516462262.0885504894201e-180.469581954014737
DLPFCADediting_615661chr17_39180572_-0.0003138151097913150.2033508268334140.1174000197880920.08911333973836071.29362716126928e-130.404223507134884
DLPFCADediting_615663chr17_39180579_-0.0005566877250846750.1949568909261010.1022863717298950.0929720120601851.06489922289959e-110.373515573150867
DLPFCADediting_615684chr17_39181238_-0.0170198815914150.1354534805559250.3856419027351990.04944300189080481.87150088474451e-120.386005447799305
DLPFCADediting_615723chr17_39182146_-0.004468780135709590.1610679596964250.2127004600155110.070975368788131.15651847726768e-110.372909229645758
DLPFCADediting_615732chr17_39182533_-0.3676447679406940.0513409839734360.89364949214555-0.007623641322103084.26547788740126e-080.304999899659646
DLPFCADediting_615733chr17_39182536_-0.01177036792061860.1429092878063880.6781502722625960.02366205531268031.31410205145482e-140.418978750257281
DLPFCADediting_615736chr17_39182580_-0.00915546447403970.1478050913226470.1586725922716480.08025208334343554.10849557983771e-080.305351242103264

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC6.15941967204462e-500.7156863955282371.09557924209316e-940.8659443911079420.5534057301063370.0337879618585555
AC6.49027266585351e-630.8232251837738614.7097914724218e-820.8797627988894320.3450245152708850.0599685344309062
PCC3.60263968466135e-740.9099553257677693.71784487550308e-870.9352180270326960.9489762599377490.00466089966838036
TCX2.98153905609415e-170.6192777976363595.05907310648685e-310.7727761290224243.02372769753955e-05-0.33359687880205
FP4.29041250350409e-260.6860031673694941.02186743649492e-160.5698890545806080.164109055112310.104739471972034
IFG9.41654176125381e-060.7624502645668374.6145634329311e-060.7783862217478430.717140632518344-0.0762549108625381
PG7.57916843926519e-050.2860088574793049.68366436138102e-100.4293285822098220.0843194074677038-0.126911137921637
STG1.30290131334533e-180.7833286922358598.68871278946962e-140.7033086725068770.544085857706522-0.0671215347086798

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Relation with AD stages for CACNB1

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
TCXADediting_615686chr17_39181258_-1.53810621273163e-05-0.406446528048251
TCXADediting_615727chr17_39182444_-0.00106607358279261-0.313515456291315
TCXADediting_615736chr17_39182580_-0.000288238547421393-0.345349487034595
TCXADediting_615738chr17_39182619_-0.00122477629791797-0.309926185266302
TCXADediting_615740chr17_39182626_-0.000716217319523089-0.323564576065294

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
PG2.51524723313853e-07-0.36727545214796

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RelatedDrugs for CACNB1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
CACNB1Q02641DB00308IbutilideVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved
CACNB1Q02641DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved
CACNB1Q02641DB00661VerapamilVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved
CACNB1Q02641DB00898EthanolVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved
CACNB1Q02641DB04855DronedaroneVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved
CACNB1Q02641DB00393NimodipineVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved|investigational
CACNB1Q02641DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1small moleculeapproved|investigational|vet_approved

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RelatedDiseases for CACNB1

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource