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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for UNG

check button Gene summary
Gene informationGene symbol

UNG

Gene ID

7374

Gene nameuracil DNA glycosylase
SynonymsDGU|HIGM4|HIGM5|UDG|UNG1|UNG15|UNG2
Cytomap

12q24.11

Type of geneprotein-coding
Descriptionuracil-DNA glycosylaseuracil-DNA glycosylase 1, uracil-DNA glycosylase 2
Modification date20200313
UniProtAcc

P13051,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
UNG

GO:0097510

base-excision repair, AP site formation via deaminated base removal

18973764


Top

RNA A-to-I events for UNG

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_297346(109099906, +), ADediting_297347(109099941, +), ADediting_297348(109099942, +), ADediting_297349(109099974, +), ADediting_297350(109101157, +), ADediting_297351(109101193, +), ADediting_297352(109101352, +), ADediting_297353(109101364, +), ADediting_297354(109104123, +), ADediting_297355(109104185, +), ADediting_297356(109104258, +), ADediting_297357(109104310, +), ADediting_297358(109104316, +), ADediting_297359(109104322, +), ADediting_297360(109104792, +), ADediting_297361(109104975, +), ADediting_297362(109104994, +), ADediting_297363(109105012, +), ADediting_297364(109105013, +), ADediting_297365(109105030, +), ADediting_297366(109105046, +), ADediting_297367(109105052, +), ADediting_297368(109105054, +), ADediting_297369(109105088, +), ADediting_297370(109105094, +), ADediting_297371(109105097, +), ADediting_297372(109105114, +), ADediting_297373(109105123, +), ADediting_297374(109105148, +), ADediting_297375(109105149, +), ADediting_297376(109105161, +), ADediting_297377(109105176, +), ADediting_297378(109105182, +), ADediting_297379(109105188, +), ADediting_297380(109105196, +), ADediting_297381(109106644, +), ADediting_297382(109106649, +), ADediting_297383(109106652, +), ADediting_297384(109106713, +), ADediting_297385(109106715, +), ADediting_297386(109106717, +), ADediting_297387(109106737, +), ADediting_297388(109106738, +), ADediting_297389(109106752, +), ADediting_297390(109106778, +), ADediting_297391(109106784, +), ADediting_297392(109106817, +), ADediting_297393(109107221, +), ADediting_297394(109107224, +), ADediting_297395(109107252, +), ADediting_297396(109107270, +), ADediting_297397(109107271, +), ADediting_297398(109107286, +), ADediting_297399(109107287, +), ADediting_297400(109107294, +), ADediting_297401(109107300, +), ADediting_297402(109107301, +), ADediting_297403(109107304, +), ADediting_297404(109107330, +), ADediting_297405(109107340, +), ADediting_297406(109107342, +), ADediting_297407(109107353, +), ADediting_297408(109107393, +), ADediting_297409(109107708, +), ADediting_297410(109107777, +), ADediting_297411(109107799, +), ADediting_297412(109108362, +), ADediting_297413(109108370, +), ADediting_297414(109108385, +), ADediting_297415(109108387, +), ADediting_297416(109108393, +), ADediting_297417(109108400, +), ADediting_297418(109108451, +), ADediting_297419(109108480, +), ADediting_297420(109108481, +), ADediting_297421(109108482, +), ADediting_297422(109108485, +), ADediting_297423(109108495, +), ADediting_297424(109108501, +), ADediting_297425(109108517, +), ADediting_297426(109108541, +), ADediting_297427(109108552, +), ADediting_297428(109108557, +), ADediting_297429(109108571, +), ADediting_297430(109108583, +), ADediting_297431(109108587, +), ADediting_297432(109108595, +), ADediting_297433(109108694, +), ADediting_297434(109108698, +), ADediting_297435(109108700, +), ADediting_297436(109108710, +), ADediting_297437(109108717, +), ADediting_297438(109108731, +), ADediting_297439(109108743, +), ADediting_297440(109108748, +), ADediting_297441(109108760, +), ADediting_297442(109108764, +), ADediting_297443(109108778, +), ADediting_297444(109108804, +), ADediting_297445(109108815, +), ADediting_297446(109108832, +), ADediting_297447(109108842, +), ADediting_297448(109108893, +), ADediting_297449(109108906, +), ADediting_297450(109108914, +), ADediting_297451(109109510, +), ADediting_297452(109109520, +), ADediting_297453(109109528, +), ADediting_297454(109109529, +), ADediting_297455(109109534, +), ADediting_297456(109109551, +), ADediting_297457(109109565, +), ADediting_297458(109109574, +), ADediting_297459(109109602, +), ADediting_297460(109109606, +), ADediting_297461(109109607, +), ADediting_297462(109109612, +), ADediting_297463(109109618, +), ADediting_297464(109109621, +), ADediting_297465(109109622, +), ADediting_297466(109109636, +), ADediting_297467(109109652, +), ADediting_297468(109109662, +), ADediting_297469(109109668, +), ADediting_297470(109109672, +), ADediting_297471(109109680, +), ADediting_297472(109109689, +), ADediting_297473(109109704, +), ADediting_297474(109109724, +), ADediting_1529698(109104229, +), ADediting_1529699(109104249, +), ADediting_1529700(109105065, +), ADediting_1529701(109105074, +), ADediting_1529702(109105111, +), ADediting_1529703(109105120, +), ADediting_1529704(109106703, +), ADediting_1529705(109107305, +), ADediting_1529706(109107665, +), ADediting_1529707(109107705, +), ADediting_1529708(109107772, +), ADediting_1529709(109108449, +), ADediting_1529710(109108915, +), ADediting_1529711(109109537, +),

Top

RNA editing positional annotations for UNG using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
ADediting_297371chr12_109105097_+stoplossENST00000539287.5c.A776Gp.X259W...

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_297346chr12_109099906_+intronic
ADediting_297347chr12_109099941_+intronic
ADediting_297348chr12_109099942_+intronic
ADediting_297349chr12_109099974_+intronic
ADediting_297350chr12_109101157_+intronic
ADediting_297351chr12_109101193_+intronic
ADediting_297352chr12_109101352_+intronic
ADediting_297353chr12_109101364_+intronic
ADediting_297354chr12_109104123_+intronic
ADediting_297355chr12_109104185_+intronic
ADediting_297356chr12_109104258_+intronic
ADediting_297357chr12_109104310_+intronic
ADediting_297358chr12_109104316_+intronic
ADediting_297359chr12_109104322_+intronic
ADediting_297360chr12_109104792_+intronic
ADediting_297361chr12_109104975_+intronic
ADediting_297362chr12_109104994_+intronic
ADediting_297363chr12_109105012_+intronic
ADediting_297364chr12_109105013_+intronic
ADediting_297365chr12_109105030_+intronic
ADediting_297366chr12_109105046_+intronic
ADediting_297367chr12_109105052_+intronic
ADediting_297368chr12_109105054_+intronic
ADediting_297369chr12_109105088_+intronic
ADediting_297370chr12_109105094_+splicing
ADediting_297371chr12_109105097_+exonic
ADediting_297372chr12_109105114_+UTR3
ADediting_297373chr12_109105123_+UTR3
ADediting_297374chr12_109105148_+UTR3
ADediting_297375chr12_109105149_+UTR3
ADediting_297376chr12_109105161_+UTR3
ADediting_297377chr12_109105176_+UTR3
ADediting_297378chr12_109105182_+UTR3
ADediting_297379chr12_109105188_+UTR3
ADediting_297380chr12_109105196_+UTR3
ADediting_297381chr12_109106644_+intronic
ADediting_297382chr12_109106649_+intronic
ADediting_297383chr12_109106652_+intronic
ADediting_297384chr12_109106713_+intronic
ADediting_297385chr12_109106715_+intronic
ADediting_297386chr12_109106717_+intronic
ADediting_297387chr12_109106737_+intronic
ADediting_297388chr12_109106738_+intronic
ADediting_297389chr12_109106752_+intronic
ADediting_297390chr12_109106778_+intronic
ADediting_297391chr12_109106784_+intronic
ADediting_297392chr12_109106817_+intronic
ADediting_297393chr12_109107221_+intronic
ADediting_297394chr12_109107224_+intronic
ADediting_297395chr12_109107252_+intronic
ADediting_297396chr12_109107270_+intronic
ADediting_297397chr12_109107271_+intronic
ADediting_297398chr12_109107286_+intronic
ADediting_297399chr12_109107287_+intronic
ADediting_297400chr12_109107294_+intronic
ADediting_297401chr12_109107300_+intronic
ADediting_297402chr12_109107301_+intronic
ADediting_297403chr12_109107304_+intronic
ADediting_297404chr12_109107330_+intronic
ADediting_297405chr12_109107340_+intronic
ADediting_297406chr12_109107342_+intronic
ADediting_297407chr12_109107353_+intronic
ADediting_297408chr12_109107393_+intronic
ADediting_297409chr12_109107708_+intronic
ADediting_297410chr12_109107777_+intronic
ADediting_297411chr12_109107799_+intronic
ADediting_297412chr12_109108362_+intronic
ADediting_297413chr12_109108370_+intronic
ADediting_297414chr12_109108385_+intronic
ADediting_297415chr12_109108387_+intronic
ADediting_297416chr12_109108393_+intronic
ADediting_297417chr12_109108400_+intronic
ADediting_297418chr12_109108451_+intronic
ADediting_297419chr12_109108480_+intronic
ADediting_297420chr12_109108481_+intronic
ADediting_297421chr12_109108482_+intronic
ADediting_297422chr12_109108485_+intronic
ADediting_297423chr12_109108495_+intronic
ADediting_297424chr12_109108501_+intronic
ADediting_297425chr12_109108517_+intronic
ADediting_297426chr12_109108541_+intronic
ADediting_297427chr12_109108552_+intronic
ADediting_297428chr12_109108557_+intronic
ADediting_297429chr12_109108571_+intronic
ADediting_297430chr12_109108583_+intronic
ADediting_297431chr12_109108587_+intronic
ADediting_297432chr12_109108595_+intronic
ADediting_297433chr12_109108694_+intronic
ADediting_297434chr12_109108698_+intronic
ADediting_297435chr12_109108700_+intronic
ADediting_297436chr12_109108710_+intronic
ADediting_297437chr12_109108717_+intronic
ADediting_297438chr12_109108731_+intronic
ADediting_297439chr12_109108743_+intronic
ADediting_297440chr12_109108748_+intronic
ADediting_297441chr12_109108760_+intronic
ADediting_297442chr12_109108764_+intronic
ADediting_297443chr12_109108778_+intronic
ADediting_297444chr12_109108804_+intronic
ADediting_297445chr12_109108815_+intronic
ADediting_297446chr12_109108832_+intronic
ADediting_297447chr12_109108842_+intronic
ADediting_297448chr12_109108893_+intronic
ADediting_297449chr12_109108906_+intronic
ADediting_297450chr12_109108914_+intronic
ADediting_297451chr12_109109510_+intronic
ADediting_297452chr12_109109520_+intronic
ADediting_297453chr12_109109528_+intronic
ADediting_297454chr12_109109529_+intronic
ADediting_297455chr12_109109534_+intronic
ADediting_297456chr12_109109551_+intronic
ADediting_297457chr12_109109565_+intronic
ADediting_297458chr12_109109574_+intronic
ADediting_297459chr12_109109602_+intronic
ADediting_297460chr12_109109606_+intronic
ADediting_297461chr12_109109607_+intronic
ADediting_297462chr12_109109612_+intronic
ADediting_297463chr12_109109618_+intronic
ADediting_297464chr12_109109621_+intronic
ADediting_297465chr12_109109622_+intronic
ADediting_297466chr12_109109636_+intronic
ADediting_297467chr12_109109652_+intronic
ADediting_297468chr12_109109662_+intronic
ADediting_297469chr12_109109668_+intronic
ADediting_297470chr12_109109672_+intronic
ADediting_297471chr12_109109680_+intronic
ADediting_297472chr12_109109689_+intronic
ADediting_297473chr12_109109704_+intronic
ADediting_297474chr12_109109724_+intronic
ADediting_1529698chr12_109104229_+intronic
ADediting_1529699chr12_109104249_+intronic
ADediting_1529700chr12_109105065_+intronic
ADediting_1529701chr12_109105074_+intronic
ADediting_1529702chr12_109105111_+UTR3
ADediting_1529703chr12_109105120_+UTR3
ADediting_1529704chr12_109106703_+intronic
ADediting_1529705chr12_109107305_+intronic
ADediting_1529706chr12_109107665_+intronic
ADediting_1529707chr12_109107705_+intronic
ADediting_1529708chr12_109107772_+intronic
ADediting_1529709chr12_109108449_+intronic
ADediting_1529710chr12_109108915_+intronic
ADediting_1529711chr12_109109537_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_297346chr12_109099906_+SINEAluName=AluSz
ADediting_297347chr12_109099941_+SINEAluName=AluSz
ADediting_297348chr12_109099942_+SINEAluName=AluSz
ADediting_297349chr12_109099974_+SINEAluName=AluSz
ADediting_297350chr12_109101157_+SINEAluName=AluSc
ADediting_297351chr12_109101193_+SINEAluName=AluSc
ADediting_297352chr12_109101352_+SINEAluName=AluSc
ADediting_297353chr12_109101364_+SINEAluName=AluSc
ADediting_297354chr12_109104123_+SINEAluName=AluSx1
ADediting_297355chr12_109104185_+SINEAluName=AluSx1
ADediting_297356chr12_109104258_+SINEAluName=AluSx1
ADediting_297357chr12_109104310_+SINEAluName=AluSx1
ADediting_297358chr12_109104316_+SINEAluName=AluSx1
ADediting_297359chr12_109104322_+SINEAluName=AluSx1
ADediting_297361chr12_109104975_+SINEAluName=AluSx1
ADediting_297362chr12_109104994_+SINEAluName=AluSx1
ADediting_297363chr12_109105012_+SINEAluName=AluSx1
ADediting_297364chr12_109105013_+SINEAluName=AluSx1
ADediting_297365chr12_109105030_+SINEAluName=AluSx1
ADediting_297366chr12_109105046_+SINEAluName=AluSx1
ADediting_297367chr12_109105052_+SINEAluName=AluSx1
ADediting_297368chr12_109105054_+SINEAluName=AluSx1
ADediting_297369chr12_109105088_+SINEAluName=AluSx1
ADediting_297370chr12_109105094_+SINEAluName=AluSx1
ADediting_297371chr12_109105097_+SINEAluName=AluSx1
ADediting_297372chr12_109105114_+SINEAluName=AluSx1
ADediting_297373chr12_109105123_+SINEAluName=AluSx1
ADediting_297374chr12_109105148_+SINEAluName=AluSx1
ADediting_297375chr12_109105149_+SINEAluName=AluSx1
ADediting_297376chr12_109105161_+SINEAluName=AluSx1
ADediting_297377chr12_109105176_+SINEAluName=AluSx1
ADediting_297378chr12_109105182_+SINEAluName=AluSx1
ADediting_297379chr12_109105188_+SINEAluName=AluSx1
ADediting_297380chr12_109105196_+SINEAluName=AluSx1
ADediting_297381chr12_109106644_+SINEAluName=AluSx3
ADediting_297382chr12_109106649_+SINEAluName=AluSx3
ADediting_297383chr12_109106652_+SINEAluName=AluSx3
ADediting_297384chr12_109106713_+SINEAluName=AluSx3
ADediting_297385chr12_109106715_+SINEAluName=AluSx3
ADediting_297386chr12_109106717_+SINEAluName=AluSx3
ADediting_297387chr12_109106737_+SINEAluName=AluSx3
ADediting_297388chr12_109106738_+SINEAluName=AluSx3
ADediting_297389chr12_109106752_+SINEAluName=AluSx3
ADediting_297390chr12_109106778_+SINEAluName=AluSx3
ADediting_297391chr12_109106784_+SINEAluName=AluSx3
ADediting_297392chr12_109106817_+SINEAluName=AluSx3
ADediting_297393chr12_109107221_+SINEAluName=AluJb
ADediting_297394chr12_109107224_+SINEAluName=AluJb
ADediting_297395chr12_109107252_+SINEAluName=AluJb
ADediting_297396chr12_109107270_+SINEAluName=AluJb
ADediting_297397chr12_109107271_+SINEAluName=AluJb
ADediting_297398chr12_109107286_+SINEAluName=AluJb
ADediting_297399chr12_109107287_+SINEAluName=AluJb
ADediting_297400chr12_109107294_+SINEAluName=AluJb
ADediting_297401chr12_109107300_+SINEAluName=AluJb
ADediting_297402chr12_109107301_+SINEAluName=AluJb
ADediting_297403chr12_109107304_+SINEAluName=AluJb
ADediting_297404chr12_109107330_+SINEAluName=AluJb
ADediting_297405chr12_109107340_+SINEAluName=AluJb
ADediting_297406chr12_109107342_+SINEAluName=AluJb
ADediting_297407chr12_109107353_+SINEAluName=AluJb
ADediting_297408chr12_109107393_+SINEAluName=AluJb
ADediting_297409chr12_109107708_+SINEAluName=AluSp
ADediting_297410chr12_109107777_+SINEAluName=AluSp
ADediting_297411chr12_109107799_+SINEAluName=AluSp
ADediting_297412chr12_109108362_+SINEAluName=AluJb
ADediting_297413chr12_109108370_+SINEAluName=AluJb
ADediting_297414chr12_109108385_+SINEAluName=AluJb
ADediting_297415chr12_109108387_+SINEAluName=AluJb
ADediting_297416chr12_109108393_+SINEAluName=AluJb
ADediting_297417chr12_109108400_+SINEAluName=AluJb
ADediting_297418chr12_109108451_+SINEAluName=AluJb
ADediting_297419chr12_109108480_+SINEAluName=AluJb
ADediting_297420chr12_109108481_+SINEAluName=AluJb
ADediting_297421chr12_109108482_+SINEAluName=AluJb
ADediting_297422chr12_109108485_+SINEAluName=AluJb
ADediting_297423chr12_109108495_+SINEAluName=AluJb
ADediting_297424chr12_109108501_+SINEAluName=AluJb
ADediting_297425chr12_109108517_+SINEAluName=AluJb
ADediting_297426chr12_109108541_+SINEAluName=AluJb
ADediting_297427chr12_109108552_+SINEAluName=AluJb
ADediting_297428chr12_109108557_+SINEAluName=AluJb
ADediting_297429chr12_109108571_+SINEAluName=AluJb
ADediting_297430chr12_109108583_+SINEAluName=AluJb
ADediting_297431chr12_109108587_+SINEAluName=AluJb
ADediting_297432chr12_109108595_+SINEAluName=AluJb
ADediting_297433chr12_109108694_+SINEAluName=AluJr
ADediting_297434chr12_109108698_+SINEAluName=AluJr
ADediting_297435chr12_109108700_+SINEAluName=AluJr
ADediting_297436chr12_109108710_+SINEAluName=AluJr
ADediting_297437chr12_109108717_+SINEAluName=AluJr
ADediting_297438chr12_109108731_+SINEAluName=AluJr
ADediting_297439chr12_109108743_+SINEAluName=AluJr
ADediting_297440chr12_109108748_+SINEAluName=AluJr
ADediting_297441chr12_109108760_+SINEAluName=AluJr
ADediting_297442chr12_109108764_+SINEAluName=AluJr
ADediting_297443chr12_109108778_+SINEAluName=AluJr
ADediting_297444chr12_109108804_+SINEAluName=AluJr
ADediting_297445chr12_109108815_+SINEAluName=AluJr
ADediting_297446chr12_109108832_+SINEAluName=AluJr
ADediting_297447chr12_109108842_+SINEAluName=AluJr
ADediting_297448chr12_109108893_+SINEAluName=AluJr
ADediting_297449chr12_109108906_+SINEAluName=AluJr
ADediting_297450chr12_109108914_+SINEAluName=AluJr
ADediting_297451chr12_109109510_+SINEAluName=AluSc
ADediting_297452chr12_109109520_+SINEAluName=AluSc
ADediting_297453chr12_109109528_+SINEAluName=AluSc
ADediting_297454chr12_109109529_+SINEAluName=AluSc
ADediting_297455chr12_109109534_+SINEAluName=AluSc
ADediting_297456chr12_109109551_+SINEAluName=AluSc
ADediting_297457chr12_109109565_+SINEAluName=AluSc
ADediting_297458chr12_109109574_+SINEAluName=AluSc
ADediting_297459chr12_109109602_+SINEAluName=AluSc
ADediting_297460chr12_109109606_+SINEAluName=AluSc
ADediting_297461chr12_109109607_+SINEAluName=AluSc
ADediting_297462chr12_109109612_+SINEAluName=AluSc
ADediting_297463chr12_109109618_+SINEAluName=AluSc
ADediting_297464chr12_109109621_+SINEAluName=AluSc
ADediting_297465chr12_109109622_+SINEAluName=AluSc
ADediting_297466chr12_109109636_+SINEAluName=AluSc
ADediting_297467chr12_109109652_+SINEAluName=AluSc
ADediting_297468chr12_109109662_+SINEAluName=AluSc
ADediting_297469chr12_109109668_+SINEAluName=AluSc
ADediting_297470chr12_109109672_+SINEAluName=AluSc
ADediting_297471chr12_109109680_+SINEAluName=AluSc
ADediting_297472chr12_109109689_+SINEAluName=AluSc
ADediting_297473chr12_109109704_+SINEAluName=AluSc
ADediting_297474chr12_109109724_+SINEAluName=AluSc
ADediting_1529698chr12_109104229_+SINEAluName=AluSx1
ADediting_1529699chr12_109104249_+SINEAluName=AluSx1
ADediting_1529700chr12_109105065_+SINEAluName=AluSx1
ADediting_1529701chr12_109105074_+SINEAluName=AluSx1
ADediting_1529702chr12_109105111_+SINEAluName=AluSx1
ADediting_1529703chr12_109105120_+SINEAluName=AluSx1
ADediting_1529704chr12_109106703_+SINEAluName=AluSx3
ADediting_1529705chr12_109107305_+SINEAluName=AluJb
ADediting_1529706chr12_109107665_+SINEAluName=AluSp
ADediting_1529707chr12_109107705_+SINEAluName=AluSp
ADediting_1529708chr12_109107772_+SINEAluName=AluSp
ADediting_1529709chr12_109108449_+SINEAluName=AluJb
ADediting_1529710chr12_109108915_+SINEAluName=AluJr
ADediting_1529711chr12_109109537_+SINEAluName=AluSc

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RNA A-to-I editing events in the alternative splicing sites for UNG

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for UNG

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for UNG

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for UNG


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_496066chr15_66496985_-ENSG00000076248.10ENST00000242576.6UNG-201hsa-miR-4512chr121091104601091104667mer-m8109110446109110467142-17.72
ADediting_496066chr15_66496985_-ENSG00000076248.10ENST00000336865.6UNG-202hsa-miR-4512chr121091104601091104667mer-m8109110446109110467142-17.72

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1097295chr3_85385762_+ENSG00000076248.10ENST00000242576.6UNG-201hsa-miR-5688chr121091109641091109718mer-1a109110949109110971150-13.84
ADediting_1097295chr3_85385762_+ENSG00000076248.10ENST00000242576.6UNG-201hsa-miR-5688chr121091109781091109858mer-1a109110965109110985150-10.91
ADediting_1097295chr3_85385762_+ENSG00000076248.10ENST00000336865.6UNG-202hsa-miR-5688chr121091109641091109718mer-1a109110949109110971150-13.84
ADediting_1556067chr19_40282625_-ENSG00000076248.10ENST00000242576.6UNG-201hsa-miR-641chr121091101661091101727mer-m8109110149109110173152-14.46
ADediting_1556067chr19_40282625_-ENSG00000076248.10ENST00000336865.6UNG-202hsa-miR-641chr121091101661091101727mer-m8109110149109110173152-14.46
ADediting_1631458chr19_40282624_-ENSG00000076248.10ENST00000242576.6UNG-201hsa-miR-641chr121091101661091101727mer-m8109110149109110173152-14.46
ADediting_1631458chr19_40282624_-ENSG00000076248.10ENST00000336865.6UNG-202hsa-miR-641chr121091101661091101727mer-m8109110149109110173152-14.46
ADediting_527135chr16_24203190_+ENSG00000076248.10ENST00000242576.6UNG-201hsa-miR-1273h-3pchr121091108881091108947mer-m8109110874109110895152-18.75
ADediting_527135chr16_24203190_+ENSG00000076248.10ENST00000336865.6UNG-202hsa-miR-1273h-3pchr121091108881091108947mer-m8109110874109110895152-18.75

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for UNG

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for UNG

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFCADediting_297355chr12_109104185_+0.899474893777936-0.007203770054260070.0517711347614225-0.1105781011183795.18347025184578e-080.303166024672267
CERADediting_297358chr12_109104316_+0.003969246932791160.2338849968084175.31108932616504e-050.3237625057811980.07385220564509320.14638834965862
DLPFCADediting_297373chr12_109105123_+0.01426451572835690.1390657422054190.3594466804113780.05222460229686811.69040651125832e-100.352479220547906
CERADediting_297373chr12_109105123_+3.86709878383318e-060.366922843908832.91653095099882e-070.4041390275902070.2436567222999240.0957771651990275
CERADediting_297380chr12_109105196_+2.16880724401044e-050.3392451626153177.39306265697305e-060.3568223273837230.1367010619383730.122076405718197
DLPFCADediting_297386chr12_109106717_+0.0006305801468416020.1930855101893690.3585393750889330.05232316431325835.09937351180285e-210.500068347865602
DLPFCADediting_297393chr12_109107221_+0.005717091972997110.1566237267051620.02703577649749240.1255861733728211.58363436340206e-090.33424092696281
DLPFCADediting_297395chr12_109107252_+0.01395564435635740.1395080319986030.09110186397558640.09612959778820332.64755431909435e-080.309434459499065
CERADediting_297395chr12_109107252_+7.084801568634e-060.3574968003792382.42659950316753e-060.3739806353601390.8529217405576410.0152639855861764
DLPFCADediting_297396chr12_109107270_+0.05040567093400280.1112263332130040.7060111202838280.02150899199712682.53337674584409e-090.330255401305833
CERADediting_297396chr12_109107270_+0.000348043866513160.288220058085460.0001620941305103940.3032177441286330.5471139601596690.0495447352703354
CERADediting_297397chr12_109107271_+0.003374274697515190.2378927312725410.0001243784684614090.3082317939445180.536422500437438-0.050871283759338
DLPFCADediting_297399chr12_109107287_+0.002317396504335540.1724126343931070.07055605193097790.1028488804782671.51608033557582e-100.353337179519204
DLPFCADediting_297400chr12_109107294_+0.03155525729201780.1221476110905910.9253317900978370.005344475859043384.50480168419744e-090.325293210869399
DLPFCADediting_297402chr12_109107301_+0.08069750590373220.09935901050275880.3892530321163550.0490687309546251.24989841334789e-080.316268680665103
DLPFCADediting_297403chr12_109107304_+0.01542587500820630.1374745906672670.5018136777247240.03828720147267123.50732314136647e-110.364633335791613
DLPFCADediting_297404chr12_109107330_+0.005851719266640550.1561980660712360.8340765094068870.01194528048156331.66124566096969e-130.402564692320494
DLPFCADediting_297418chr12_109108451_+0.08594100879673340.09769214798515180.904832897676308-0.006817930261189763.10717616721517e-090.328505506587887
CERADediting_297418chr12_109108451_+0.0006389323347727110.2756785143341571.97064226101599e-050.3408535764606590.03538696392616990.171939807573343
DLPFCADediting_297421chr12_109108482_+0.053019762832710.109997678977880.5266372829360990.03609445830407986.39886303861696e-080.301169863650119
DLPFCADediting_297422chr12_109108485_+0.2629807718403060.06376903499789550.951993751814648-0.003433174349766986.64519149948735e-080.300810314363676
DLPFCADediting_297423chr12_109108495_+0.4774746403380410.04049334428493650.6137466224374-0.02877720348388719.92776911628183e-090.318331609086894
DLPFCADediting_297424chr12_109108501_+0.04463581427861390.1141388505361860.3067372158880170.05823692258975928.48543320276378e-090.319728831630814
DLPFCADediting_297428chr12_109108557_+0.630063386383806-0.02746095547320680.0347892664622943-0.1199369841941667.6364054353205e-100.340317464634527
DLPFCADediting_297429chr12_109108571_+0.981516413549683-0.001321180011854510.209136273322607-0.07153038507933223.48139161075645e-080.306897603010093
DLPFCADediting_297430chr12_109108583_+0.07297119776064020.1019824904782510.391274706368929-0.04886011505359017.56620097215561e-130.392306718969008
DLPFCADediting_297431chr12_109108587_+0.2259060526437620.06897530288180120.215255535308374-0.0705815924319297.43702228251464e-150.422541803976664
DLPFCADediting_297432chr12_109108595_+0.1906992935064710.0745162225573190.148182098688924-0.08231939482444831.25690694571925e-170.459862656054047
DLPFCADediting_297433chr12_109108694_+0.2670087758574650.06323482042203790.816330934170954-0.01324478480621331.28421314096381e-100.354640619191922
DLPFCADediting_297434chr12_109108698_+0.3158793121608060.05714869917102740.722882492252859-0.02022006572467667.26970601592275e-100.340722738569737
DLPFCADediting_297435chr12_109108700_+0.7014853173476070.02185659242363050.357456437306488-0.05244101012592865.76760846496826e-100.342621094658695
DLPFCADediting_297441chr12_109108760_+0.01409762760503270.1393036619345510.3478574297223440.05349552491401763.24176662126691e-110.365228518125515
DLPFCADediting_297442chr12_109108764_+0.03118253656173510.1224146555335960.6477076795000590.02605380597995211.97305668788149e-100.351255978996497
DLPFCADediting_297443chr12_109108778_+0.1901530654791160.07460783487756730.38468640504431-0.04954238904863191.1267740456511e-160.447548652839129
CERADediting_297443chr12_109108778_+0.000179461116272780.3012665738767195.22941205888881e-050.324037634113420.07039221737096240.1481581142596
CERADediting_297450chr12_109108914_+2.11918840288238e-060.3760013828477545.56529821162024e-070.395254320020020.004608068049547580.230143610598858

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC3.42267985430684e-110.3648181363333871.23028071584932e-070.2948772143948556.30053809986645e-080.301317121405991
AC2.15476464690833e-330.6658263502920924.87797014777529e-160.4833037754326881.13899055799266e-320.660179869345515
PCC0.0002680955032297680.2608269559666930.00185036392936810.2238705893110445.0650158682741e-070.353995490737782
CER1.23976815956053e-090.4704752140400418.66265889143553e-110.4982940088334741.10811609620995e-150.59412738271293
TCX1.91541861508318e-060.377500742912710.1642462710124380.1141524051979751.20389990352355e-060.384293599345222
FP8.85671650492404e-100.43893473211550.0003363022920213270.2657747854117784.03788788725982e-130.508977477288789
IFG5.43820077059696e-050.7173662202049764.41862199732189e-050.7231928801349960.03031357254875170.433702937148681
PG8.99850559368726e-350.7493293457746851.38651805112006e-110.4694619724672950.01819566155765930.173020162195295
STG8.74620876333365e-100.6077721881413350.01699742024559810.2598210541793850.008203609307287860.286652670780309

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Relation with AD stages for UNG

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER3.69781070383001e-060.428600551742289
TCX5.3693046202829e-110.583227682444303

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RelatedDrugs for UNG

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for UNG

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource
UNGC1720958Hyper-IgM Immunodeficiency Syndrome, Type 52CTD_human;ORPHANET;UNIPROT
UNGC0005859Bloom Syndrome1CTD_human
UNGC0009402Colorectal Carcinoma1CTD_human
UNGC0009404Colorectal Neoplasms1CTD_human
UNGC1527249Colorectal Cancer1CTD_human