ADeditome: functional annotation of RNA A-to-I editing in AD

Gene summary for TRAF6

Gene summary

Gene information	Gene symbol	TRAF6
	Gene ID	7189
	Gene name	TNF receptor associated factor 6
	Synonyms	MGC:3310\|RNF85
	Cytomap	11p12
	Type of gene	protein-coding
	Description	TNF receptor-associated factor 6E3 ubiquitin-protein ligase TRAF6RING finger protein 85RING-type E3 ubiquitin transferase TRAF6TNF receptor-associated factor 6, E3 ubiquitin protein ligaseinterleukin-1 signal transducer
	Modification date	20200313
	UniProtAcc	Q9Y4K3,
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
TRAF6	GO:0000209	protein polyubiquitination	15125833\|19675569
TRAF6	GO:0032147	activation of protein kinase activity	17135271
TRAF6	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	17135271
TRAF6	GO:0043507	positive regulation of JUN kinase activity	11751921
TRAF6	GO:0045672	positive regulation of osteoclast differentiation	17135271
TRAF6	GO:0045944	positive regulation of transcription by RNA polymerase II	11751921
TRAF6	GO:0051092	positive regulation of NF-kappaB transcription factor activity	11279055\|11751921\|16378096
TRAF6	GO:0051865	protein autoubiquitination	17135271\|18093978\|23776175
TRAF6	GO:0070534	protein K63-linked ubiquitination	19713527\|21068390
TRAF6	GO:0070555	response to interleukin-1	17135271
TRAF6	GO:0071222	cellular response to lipopolysaccharide	23776175
TRAF6	GO:2000679	positive regulation of transcription regulatory region DNA binding	11751921

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RNA A-to-I events for TRAF6

RNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA editing frequencies across three data sets.

The number of RNA A-to-I editing events in different types of transcripts (# event, percentage).

RNA A-to-I editing events in AD.

ADediting_250192(36486067, -), ADediting_250193(36486072, -), ADediting_250194(36486108, -), ADediting_250195(36486112, -), ADediting_250196(36486128, -), ADediting_250197(36486136, -), ADediting_250198(36486137, -), ADediting_250199(36486145, -), ADediting_250200(36486155, -), ADediting_250201(36486161, -), ADediting_250202(36486172, -), ADediting_250203(36486177, -), ADediting_250204(36486178, -), ADediting_250205(36486200, -), ADediting_250206(36486204, -), ADediting_250207(36486208, -), ADediting_250208(36486209, -), ADediting_250209(36486210, -), ADediting_250210(36486213, -), ADediting_250211(36486215, -), ADediting_250212(36486216, -), ADediting_250213(36486221, -), ADediting_250214(36486227, -), ADediting_250215(36486232, -), ADediting_250216(36486233, -), ADediting_250217(36486234, -), ADediting_250218(36486240, -), ADediting_250219(36486241, -), ADediting_250220(36486242, -), ADediting_250221(36486243, -), ADediting_250222(36486252, -), ADediting_250223(36486255, -), ADediting_250224(36486257, -), ADediting_250225(36486263, -), ADediting_250226(36486266, -), ADediting_250227(36486270, -), ADediting_250228(36486271, -), ADediting_250229(36486303, -), ADediting_250230(36486306, -), ADediting_250231(36486311, -), ADediting_250232(36486312, -), ADediting_250233(36486314, -), ADediting_250234(36486320, -), ADediting_250235(36486826, -), ADediting_250236(36486830, -), ADediting_250237(36486832, -), ADediting_250238(36486844, -), ADediting_250239(36486845, -), ADediting_250240(36486846, -), ADediting_250241(36486854, -), ADediting_250242(36486870, -), ADediting_250243(36486872, -), ADediting_250244(36486884, -), ADediting_250245(36486897, -), ADediting_250246(36486904, -), ADediting_250247(36486906, -), ADediting_250248(36486909, -), ADediting_250249(36486921, -), ADediting_250250(36486923, -), ADediting_250251(36486932, -), ADediting_250252(36486942, -), ADediting_250253(36486947, -), ADediting_250254(36486953, -), ADediting_250255(36486969, -), ADediting_250256(36486982, -), ADediting_250257(36486991, -), ADediting_250258(36487004, -), ADediting_250259(36487008, -), ADediting_250260(36487009, -), ADediting_250261(36487028, -), ADediting_250262(36487034, -), ADediting_250263(36487058, -), ADediting_250264(36487077, -), ADediting_250265(36487083, -), ADediting_1526741(36486086, -), ADediting_1526742(36486107, -), ADediting_1526743(36486116, -), ADediting_1526744(36486186, -), ADediting_1526745(36486207, -), ADediting_1526746(36486218, -), ADediting_1609687(36486330, -),

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RNA editing positional annotations for TRAF6 using Annovar

Protein coding RNA editing(s).

ADeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

ADeditome ID	Position	Variant type
ADediting_250192	chr11_36486067_-	UTR3
ADediting_250193	chr11_36486072_-	UTR3
ADediting_250194	chr11_36486108_-	UTR3
ADediting_250195	chr11_36486112_-	UTR3
ADediting_250196	chr11_36486128_-	UTR3
ADediting_250197	chr11_36486136_-	UTR3
ADediting_250198	chr11_36486137_-	UTR3
ADediting_250199	chr11_36486145_-	UTR3
ADediting_250200	chr11_36486155_-	UTR3
ADediting_250201	chr11_36486161_-	UTR3
ADediting_250202	chr11_36486172_-	UTR3
ADediting_250203	chr11_36486177_-	UTR3
ADediting_250204	chr11_36486178_-	UTR3
ADediting_250205	chr11_36486200_-	UTR3
ADediting_250206	chr11_36486204_-	UTR3
ADediting_250207	chr11_36486208_-	UTR3
ADediting_250208	chr11_36486209_-	UTR3
ADediting_250209	chr11_36486210_-	UTR3
ADediting_250210	chr11_36486213_-	UTR3
ADediting_250211	chr11_36486215_-	UTR3
ADediting_250212	chr11_36486216_-	UTR3
ADediting_250213	chr11_36486221_-	UTR3
ADediting_250214	chr11_36486227_-	UTR3
ADediting_250215	chr11_36486232_-	UTR3
ADediting_250216	chr11_36486233_-	UTR3
ADediting_250217	chr11_36486234_-	UTR3
ADediting_250218	chr11_36486240_-	UTR3
ADediting_250219	chr11_36486241_-	UTR3
ADediting_250220	chr11_36486242_-	UTR3
ADediting_250221	chr11_36486243_-	UTR3
ADediting_250222	chr11_36486252_-	UTR3
ADediting_250223	chr11_36486255_-	UTR3
ADediting_250224	chr11_36486257_-	UTR3
ADediting_250225	chr11_36486263_-	UTR3
ADediting_250226	chr11_36486266_-	UTR3
ADediting_250227	chr11_36486270_-	UTR3
ADediting_250228	chr11_36486271_-	UTR3
ADediting_250229	chr11_36486303_-	UTR3
ADediting_250230	chr11_36486306_-	UTR3
ADediting_250231	chr11_36486311_-	UTR3
ADediting_250232	chr11_36486312_-	UTR3
ADediting_250233	chr11_36486314_-	UTR3
ADediting_250234	chr11_36486320_-	UTR3
ADediting_250235	chr11_36486826_-	UTR3
ADediting_250236	chr11_36486830_-	UTR3
ADediting_250237	chr11_36486832_-	UTR3
ADediting_250238	chr11_36486844_-	UTR3
ADediting_250239	chr11_36486845_-	UTR3
ADediting_250240	chr11_36486846_-	UTR3
ADediting_250241	chr11_36486854_-	UTR3
ADediting_250242	chr11_36486870_-	UTR3
ADediting_250243	chr11_36486872_-	UTR3
ADediting_250244	chr11_36486884_-	UTR3
ADediting_250245	chr11_36486897_-	UTR3
ADediting_250246	chr11_36486904_-	UTR3
ADediting_250247	chr11_36486906_-	UTR3
ADediting_250248	chr11_36486909_-	UTR3
ADediting_250249	chr11_36486921_-	UTR3
ADediting_250250	chr11_36486923_-	UTR3
ADediting_250251	chr11_36486932_-	UTR3
ADediting_250252	chr11_36486942_-	UTR3
ADediting_250253	chr11_36486947_-	UTR3
ADediting_250254	chr11_36486953_-	UTR3
ADediting_250255	chr11_36486969_-	UTR3
ADediting_250256	chr11_36486982_-	UTR3
ADediting_250257	chr11_36486991_-	UTR3
ADediting_250258	chr11_36487004_-	UTR3
ADediting_250259	chr11_36487008_-	UTR3
ADediting_250260	chr11_36487009_-	UTR3
ADediting_250261	chr11_36487028_-	UTR3
ADediting_250262	chr11_36487034_-	UTR3
ADediting_250263	chr11_36487058_-	UTR3
ADediting_250264	chr11_36487077_-	UTR3
ADediting_250265	chr11_36487083_-	UTR3
ADediting_1526741	chr11_36486086_-	UTR3
ADediting_1526742	chr11_36486107_-	UTR3
ADediting_1526743	chr11_36486116_-	UTR3
ADediting_1526744	chr11_36486186_-	UTR3
ADediting_1526745	chr11_36486207_-	UTR3
ADediting_1526746	chr11_36486218_-	UTR3
ADediting_1609687	chr11_36486330_-	UTR3

Repat-regional RNA editing(s).

ADeditome ID	Position	Repeat family	Repeat sub family	Repeat name
ADediting_250192	chr11_36486067_-	SINE	Alu	Name=AluSz6
ADediting_250193	chr11_36486072_-	SINE	Alu	Name=AluSz6
ADediting_250194	chr11_36486108_-	SINE	Alu	Name=AluSz6
ADediting_250195	chr11_36486112_-	SINE	Alu	Name=AluSz6
ADediting_250196	chr11_36486128_-	SINE	Alu	Name=AluSz6
ADediting_250197	chr11_36486136_-	SINE	Alu	Name=AluSz6
ADediting_250198	chr11_36486137_-	SINE	Alu	Name=AluSz6
ADediting_250199	chr11_36486145_-	SINE	Alu	Name=AluSz6
ADediting_250200	chr11_36486155_-	SINE	Alu	Name=AluSz6
ADediting_250201	chr11_36486161_-	SINE	Alu	Name=AluSz6
ADediting_250202	chr11_36486172_-	SINE	Alu	Name=AluSz6
ADediting_250203	chr11_36486177_-	SINE	Alu	Name=AluSz6
ADediting_250204	chr11_36486178_-	SINE	Alu	Name=AluSz6
ADediting_250205	chr11_36486200_-	SINE	Alu	Name=AluSz6
ADediting_250206	chr11_36486204_-	SINE	Alu	Name=AluSz6
ADediting_250207	chr11_36486208_-	SINE	Alu	Name=AluSz6
ADediting_250208	chr11_36486209_-	SINE	Alu	Name=AluSz6
ADediting_250209	chr11_36486210_-	SINE	Alu	Name=AluSz6
ADediting_250210	chr11_36486213_-	SINE	Alu	Name=AluSz6
ADediting_250211	chr11_36486215_-	SINE	Alu	Name=AluSz6
ADediting_250212	chr11_36486216_-	SINE	Alu	Name=AluSz6
ADediting_250213	chr11_36486221_-	SINE	Alu	Name=AluSz6
ADediting_250214	chr11_36486227_-	SINE	Alu	Name=AluSz6
ADediting_250215	chr11_36486232_-	SINE	Alu	Name=AluSz6
ADediting_250216	chr11_36486233_-	SINE	Alu	Name=AluSz6
ADediting_250217	chr11_36486234_-	SINE	Alu	Name=AluSz6
ADediting_250218	chr11_36486240_-	SINE	Alu	Name=AluSz6
ADediting_250219	chr11_36486241_-	SINE	Alu	Name=AluSz6
ADediting_250220	chr11_36486242_-	SINE	Alu	Name=AluSz6
ADediting_250221	chr11_36486243_-	SINE	Alu	Name=AluSz6
ADediting_250222	chr11_36486252_-	SINE	Alu	Name=AluSz6
ADediting_250223	chr11_36486255_-	SINE	Alu	Name=AluSz6
ADediting_250224	chr11_36486257_-	SINE	Alu	Name=AluSz6
ADediting_250225	chr11_36486263_-	SINE	Alu	Name=AluSz6
ADediting_250226	chr11_36486266_-	SINE	Alu	Name=AluSz6
ADediting_250227	chr11_36486270_-	SINE	Alu	Name=AluSz6
ADediting_250228	chr11_36486271_-	SINE	Alu	Name=AluSz6
ADediting_250229	chr11_36486303_-	SINE	Alu	Name=AluSz6
ADediting_250230	chr11_36486306_-	SINE	Alu	Name=AluSz6
ADediting_250231	chr11_36486311_-	SINE	Alu	Name=AluSz6
ADediting_250232	chr11_36486312_-	SINE	Alu	Name=AluSz6
ADediting_250233	chr11_36486314_-	SINE	Alu	Name=AluSz6
ADediting_250234	chr11_36486320_-	SINE	Alu	Name=AluSz6
ADediting_250235	chr11_36486826_-	SINE	Alu	Name=AluSx1
ADediting_250236	chr11_36486830_-	SINE	Alu	Name=AluSx1
ADediting_250237	chr11_36486832_-	SINE	Alu	Name=AluSx1
ADediting_250238	chr11_36486844_-	SINE	Alu	Name=AluSx1
ADediting_250239	chr11_36486845_-	SINE	Alu	Name=AluSx1
ADediting_250240	chr11_36486846_-	SINE	Alu	Name=AluSx1
ADediting_250241	chr11_36486854_-	SINE	Alu	Name=AluSx1
ADediting_250242	chr11_36486870_-	SINE	Alu	Name=AluSx1
ADediting_250243	chr11_36486872_-	SINE	Alu	Name=AluSx1
ADediting_250244	chr11_36486884_-	SINE	Alu	Name=AluSx1
ADediting_250245	chr11_36486897_-	SINE	Alu	Name=AluSx1
ADediting_250246	chr11_36486904_-	SINE	Alu	Name=AluSx1
ADediting_250247	chr11_36486906_-	SINE	Alu	Name=AluSx1
ADediting_250248	chr11_36486909_-	SINE	Alu	Name=AluSx1
ADediting_250249	chr11_36486921_-	SINE	Alu	Name=AluSx1
ADediting_250250	chr11_36486923_-	SINE	Alu	Name=AluSx1
ADediting_250251	chr11_36486932_-	SINE	Alu	Name=AluSx1
ADediting_250252	chr11_36486942_-	SINE	Alu	Name=AluSx1
ADediting_250253	chr11_36486947_-	SINE	Alu	Name=AluSx1
ADediting_250254	chr11_36486953_-	SINE	Alu	Name=AluSx1
ADediting_250255	chr11_36486969_-	SINE	Alu	Name=AluSx1
ADediting_250256	chr11_36486982_-	SINE	Alu	Name=AluSx1
ADediting_250257	chr11_36486991_-	SINE	Alu	Name=AluSx1
ADediting_250258	chr11_36487004_-	SINE	Alu	Name=AluSx1
ADediting_250259	chr11_36487008_-	SINE	Alu	Name=AluSx1
ADediting_250260	chr11_36487009_-	SINE	Alu	Name=AluSx1
ADediting_250261	chr11_36487028_-	SINE	Alu	Name=AluSx1
ADediting_250262	chr11_36487034_-	SINE	Alu	Name=AluSx1
ADediting_250263	chr11_36487058_-	SINE	Alu	Name=AluSx1
ADediting_250264	chr11_36487077_-	SINE	Alu	Name=AluSx1
ADediting_250265	chr11_36487083_-	SINE	Alu	Name=AluSx1
ADediting_1526741	chr11_36486086_-	SINE	Alu	Name=AluSz6
ADediting_1526742	chr11_36486107_-	SINE	Alu	Name=AluSz6
ADediting_1526743	chr11_36486116_-	SINE	Alu	Name=AluSz6
ADediting_1526744	chr11_36486186_-	SINE	Alu	Name=AluSz6
ADediting_1526745	chr11_36486207_-	SINE	Alu	Name=AluSz6
ADediting_1526746	chr11_36486218_-	SINE	Alu	Name=AluSz6
ADediting_1609687	chr11_36486330_-	SINE	Alu	Name=AluSz6

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RNA A-to-I editing events in the alternative splicing sites for TRAF6

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

ADeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TRAF6

Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

- Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome ID

Chr

Positoing

Skipped exon

ENSG

ENSTs

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Protein coding region RNA A-to-I editings for TRAF6

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for TRAF6

RNA A-to-I editings in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1526742	chr11_36486107_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-149-5p	chr11	36486107	36486113	7mer-m8	36486106	36486128	145	-19.21
ADediting_1526744	chr11_36486186_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3622a-5p	chr11	36486181	36486187	7mer-m8	36486180	36486201	140	-20.66
ADediting_1526744	chr11_36486186_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6506-3p	chr11	36486186	36486192	7mer-m8	36486185	36486205	150	-15.13
ADediting_1609687	chr11_36486330_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-1292-3p	chr11	36486328	36486334	7mer-m8	36486327	36486346	149	-21.84
ADediting_250193	chr11_36486072_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-10a-5p	chr11	36486070	36486076	7mer-m8	36486069	36486090	147	-22.04
ADediting_250193	chr11_36486072_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-10b-5p	chr11	36486070	36486076	7mer-m8	36486069	36486089	146	-20.82
ADediting_250193	chr11_36486072_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-339-5p	chr11	36486071	36486077	7mer-m8	36486070	36486092	163	-28.5
ADediting_250193	chr11_36486072_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3620-3p	chr11	36486069	36486075	7mer-m8	36486068	36486090	154	-26
ADediting_250194	chr11_36486108_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4638-5p	chr11	36486105	36486112	8mer-1a	36486105	36486124	146	-20.28
ADediting_250196	chr11_36486128_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-550b-2-5p	chr11	36486123	36486129	7mer-m8	36486122	36486144	150	-22.52
ADediting_250196	chr11_36486128_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6778-3p	chr11	36486125	36486132	8mer-1a	36486125	36486143	143	-17.48
ADediting_250196	chr11_36486128_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6791-3p	chr11	36486125	36486131	7mer-1a	36486125	36486144	145	-24.78
ADediting_250196	chr11_36486128_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6836-3p	chr11	36486125	36486131	7mer-m8	36486124	36486144	147	-18.67
ADediting_250197	chr11_36486136_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4437	chr11	36486133	36486139	7mer-m8	36486132	36486152	146	-19.66
ADediting_250200	chr11_36486155_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6849-3p	chr11	36486155	36486161	7mer-m8	36486154	36486175	140	-18.16
ADediting_250201	chr11_36486161_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3943	chr11	36486157	36486163	7mer-m8	36486156	36486179	142	-21.9
ADediting_250203	chr11_36486177_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-8052	chr11	36486172	36486178	7mer-1a	36486172	36486190	143	-23.67
ADediting_250204	chr11_36486178_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-513a-5p	chr11	36486177	36486183	7mer-m8	36486176	36486193	160	-20.55
ADediting_250204	chr11_36486178_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-638	chr11	36486172	36486178	7mer-1a	36486172	36486196	157	-30.99
ADediting_250205	chr11_36486200_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-941	chr11	36486197	36486203	7mer-m8	36486196	36486218	146	-23.83
ADediting_250206	chr11_36486204_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3190-5p	chr11	36486199	36486205	7mer-m8	36486198	36486217	143	-16.24
ADediting_250206	chr11_36486204_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548s	chr11	36486200	36486206	7mer-m8	36486199	36486221	145	-11.19
ADediting_250207	chr11_36486208_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6844	chr11	36486207	36486213	7mer-m8	36486206	36486227	158	-7.49
ADediting_250208	chr11_36486209_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-578	chr11	36486207	36486213	7mer-m8	36486206	36486226	145	-8.19
ADediting_250208	chr11_36486209_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-643	chr11	36486208	36486215	8mer-1a	36486208	36486229	144	-9.81
ADediting_250209	chr11_36486210_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4742-3p	chr11	36486209	36486216	8mer-1a	36486209	36486231	142	-9.18
ADediting_250210	chr11_36486213_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-153-5p	chr11	36486213	36486219	7mer-m8	36486212	36486233	153	-9.52
ADediting_250210	chr11_36486213_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3680-3p	chr11	36486208	36486215	8mer-1a	36486208	36486230	140	-14.71
ADediting_250213	chr11_36486221_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4756-3p	chr11	36486221	36486227	7mer-m8	36486220	36486239	151	-16.77
ADediting_250214	chr11_36486227_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-483-5p	chr11	36486224	36486230	7mer-m8	36486223	36486244	140	-14.01
ADediting_250215	chr11_36486232_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-412-3p	chr11	36486232	36486238	7mer-m8	36486231	36486253	145	-17.3
ADediting_250215	chr11_36486232_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6754-3p	chr11	36486232	36486238	7mer-m8	36486231	36486251	142	-15.06
ADediting_250216	chr11_36486233_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-1229-3p	chr11	36486232	36486238	7mer-m8	36486231	36486253	147	-14.69
ADediting_250216	chr11_36486233_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6511a-3p	chr11	36486232	36486239	8mer-1a	36486232	36486250	147	-16.18
ADediting_250216	chr11_36486233_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6511b-3p	chr11	36486232	36486239	8mer-1a	36486232	36486251	141	-14.55
ADediting_250217	chr11_36486234_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-23a-5p	chr11	36486229	36486235	7mer-m8	36486228	36486249	140	-20.31
ADediting_250217	chr11_36486234_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-23b-5p	chr11	36486229	36486235	7mer-m8	36486228	36486248	148	-17.79
ADediting_250218	chr11_36486240_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-1255b-2-3p	chr11	36486236	36486242	7mer-m8	36486235	36486258	151	-14.82
ADediting_250220	chr11_36486242_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3190-5p	chr11	36486241	36486248	8mer-1a	36486241	36486260	154	-21.76
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3176	chr11	36486251	36486257	7mer-m8	36486250	36486268	160	-27.08
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3922-3p	chr11	36486251	36486257	7mer-m8	36486250	36486274	157	-24.26
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6878-3p	chr11	36486252	36486258	7mer-m8	36486251	36486271	148	-24.54
ADediting_250224	chr11_36486257_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4281	chr11	36486252	36486259	8mer-1a	36486252	36486269	142	-21.92
ADediting_250224	chr11_36486257_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6716-3p	chr11	36486257	36486263	7mer-m8	36486256	36486278	147	-17.97
ADediting_250225	chr11_36486263_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-331-3p	chr11	36486262	36486268	7mer-m8	36486261	36486281	140	-18.09
ADediting_250227	chr11_36486270_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3176	chr11	36486265	36486271	7mer-m8	36486264	36486281	141	-14.99
ADediting_250227	chr11_36486270_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3922-3p	chr11	36486265	36486271	7mer-m8	36486264	36486285	150	-17.08
ADediting_250227	chr11_36486270_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6878-3p	chr11	36486266	36486272	7mer-m8	36486265	36486287	141	-23.91
ADediting_250228	chr11_36486271_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5695	chr11	36486269	36486275	7mer-m8	36486268	36486290	147	-19.86
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-518a-3p	chr11	36486299	36486305	7mer-m8	36486298	36486319	145	-14.22
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-518b	chr11	36486299	36486305	7mer-m8	36486298	36486320	149	-19.74
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-518c-3p	chr11	36486299	36486305	7mer-m8	36486298	36486321	149	-20.93
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-518d-3p	chr11	36486299	36486305	7mer-m8	36486298	36486318	145	-16.4
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-518e-3p	chr11	36486300	36486306	7mer-m8	36486299	36486318	141	-11.33
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-518f-3p	chr11	36486299	36486305	7mer-m8	36486298	36486319	149	-15.43
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-526a-3p	chr11	36486299	36486305	7mer-m8	36486298	36486320	149	-15.66
ADediting_250230	chr11_36486306_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-371a-3p	chr11	36486301	36486307	7mer-m8	36486300	36486322	149	-17.31
ADediting_250231	chr11_36486311_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-625-3p	chr11	36486310	36486316	7mer-m8	36486309	36486330	140	-14.38
ADediting_250231	chr11_36486311_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-8052	chr11	36486306	36486312	7mer-1a	36486306	36486324	144	-24.46
ADediting_250232	chr11_36486312_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-638	chr11	36486306	36486312	7mer-1a	36486306	36486330	151	-30.63
ADediting_250233	chr11_36486314_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-10399-5p	chr11	36486310	36486316	7mer-m8	36486309	36486330	144	-11.21
ADediting_250233	chr11_36486314_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6504-3p	chr11	36486310	36486316	7mer-m8	36486309	36486330	148	-14.35
ADediting_250233	chr11_36486314_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-7151-3p	chr11	36486311	36486318	8mer-1a	36486311	36486331	144	-16.51
ADediting_250234	chr11_36486320_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4634	chr11	36486316	36486322	7mer-m8	36486315	36486338	151	-31.49
ADediting_250238	chr11_36486844_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3189-3p	chr11	36486843	36486849	7mer-m8	36486842	36486864	153	-24.98
ADediting_250238	chr11_36486844_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6813-3p	chr11	36486842	36486848	7mer-m8	36486841	36486861	140	-10.68
ADediting_250239	chr11_36486845_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-326	chr11	36486843	36486849	7mer-m8	36486842	36486861	140	-13.25
ADediting_250239	chr11_36486845_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-330-5p	chr11	36486843	36486849	7mer-m8	36486842	36486865	143	-20.01
ADediting_250239	chr11_36486845_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4314	chr11	36486844	36486850	7mer-m8	36486843	36486861	143	-20.84
ADediting_250239	chr11_36486845_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-514a-5p	chr11	36486842	36486848	7mer-m8	36486841	36486864	150	-18.62
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6771-5p	chr11	36486844	36486851	8mer-1a	36486844	36486863	152	-26.14
ADediting_250242	chr11_36486870_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3622a-3p	chr11	36486867	36486874	8mer-1a	36486867	36486888	144	-14.78
ADediting_250242	chr11_36486870_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3622b-3p	chr11	36486867	36486874	8mer-1a	36486867	36486887	153	-19.79
ADediting_250242	chr11_36486870_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-544b	chr11	36486870	36486876	7mer-m8	36486869	36486890	159	-21.09
ADediting_250244	chr11_36486884_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-28-5p	chr11	36486879	36486885	7mer-m8	36486878	36486898	155	-23.56
ADediting_250244	chr11_36486884_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3139	chr11	36486879	36486885	7mer-m8	36486878	36486900	158	-26.82
ADediting_250244	chr11_36486884_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-708-5p	chr11	36486879	36486885	7mer-m8	36486878	36486900	154	-22.59
ADediting_250247	chr11_36486906_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-433-5p	chr11	36486904	36486911	8mer-1a	36486904	36486927	159	-27.6
ADediting_250248	chr11_36486909_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-8074	chr11	36486904	36486910	7mer-m8	36486903	36486927	169	-27.6
ADediting_250249	chr11_36486921_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4746-5p	chr11	36486916	36486922	7mer-m8	36486915	36486937	149	-23.23
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4661-5p	chr11	36486941	36486947	7mer-m8	36486940	36486961	145	-18.81
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548ae-3p	chr11	36486937	36486943	7mer-m8	36486936	36486956	141	-6.06
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548ah-3p	chr11	36486937	36486943	7mer-m8	36486936	36486958	143	-6.06
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548aj-3p	chr11	36486937	36486943	7mer-m8	36486936	36486956	141	-6.96
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548am-3p	chr11	36486937	36486943	7mer-m8	36486936	36486958	143	-6.06
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548aq-3p	chr11	36486937	36486943	7mer-m8	36486936	36486957	141	-6.06
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548j-3p	chr11	36486937	36486943	7mer-m8	36486936	36486956	141	-6.06
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548x-3p	chr11	36486937	36486943	7mer-m8	36486936	36486955	141	-6.96
ADediting_250252	chr11_36486942_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-7844-5p	chr11	36486939	36486945	7mer-m8	36486938	36486959	164	-22.52
ADediting_250254	chr11_36486953_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-10394-3p	chr11	36486947	36486954	8mer-1a	36486947	36486974	150	-33.82
ADediting_250254	chr11_36486953_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3178	chr11	36486947	36486954	8mer-1a	36486947	36486965	146	-25.23
ADediting_250256	chr11_36486982_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-661	chr11	36486979	36486986	8mer-1a	36486979	36487002	147	-25.03
ADediting_250256	chr11_36486982_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6882-3p	chr11	36486977	36486983	7mer-m8	36486976	36486999	140	-18.29
ADediting_250257	chr11_36486991_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6089	chr11	36486986	36486992	7mer-m8	36486985	36487009	169	-39.86
ADediting_250258	chr11_36487004_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-337-5p	chr11	36487002	36487008	7mer-m8	36487001	36487022	158	-22.23
ADediting_250259	chr11_36487008_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6751-3p	chr11	36487008	36487014	7mer-m8	36487007	36487027	141	-13.02
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-17-3p	chr11	36487028	36487034	7mer-m8	36487027	36487048	150	-19.37
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-485-5p	chr11	36487024	36487030	7mer-m8	36487023	36487043	153	-18.27
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6884-5p	chr11	36487024	36487030	7mer-m8	36487023	36487046	154	-23.9
ADediting_250264	chr11_36487077_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4649-5p	chr11	36487074	36487080	7mer-m8	36487073	36487092	148	-24.4
ADediting_250264	chr11_36487077_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6729-5p	chr11	36487074	36487080	7mer-m8	36487073	36487094	150	-20.2
ADediting_250265	chr11_36487083_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-340-3p	chr11	36487082	36487088	7mer-m8	36487081	36487102	146	-18.03
ADediting_250265	chr11_36487083_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6827-3p	chr11	36487082	36487088	7mer-m8	36487081	36487101	140	-16.1

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

ADeditom_ID	Position	ENSG	ENST	Transcript name	miRNA ID	Chromosome	Targt	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
ADediting_1526741	chr11_36486086_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4505	chr11	36486083	36486089	7mer-m8	36486082	36486099	140	-22.48
ADediting_1526741	chr11_36486086_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4731-5p	chr11	36486084	36486090	7mer-m8	36486083	36486105	147	-22.47
ADediting_1526741	chr11_36486086_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5787	chr11	36486083	36486089	7mer-m8	36486082	36486102	151	-28.49
ADediting_1526741	chr11_36486086_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-637	chr11	36486085	36486091	7mer-m8	36486084	36486106	143	-21.57
ADediting_1526743	chr11_36486116_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4772-3p	chr11	36486115	36486121	7mer-m8	36486114	36486136	154	-16.78
ADediting_1526745	chr11_36486207_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4735-5p	chr11	36486203	36486209	7mer-m8	36486202	36486223	140	-4.28
ADediting_250193	chr11_36486072_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3664-5p	chr11	36486070	36486076	7mer-m8	36486069	36486087	151	-17.09
ADediting_250195	chr11_36486112_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4284	chr11	36486108	36486115	8mer-1a	36486108	36486125	151	-16.56
ADediting_250196	chr11_36486128_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-218-5p	chr11	36486123	36486129	7mer-m8	36486122	36486142	140	-11.93
ADediting_250197	chr11_36486136_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-498-5p	chr11	36486136	36486142	7mer-m8	36486135	36486157	142	-13.5
ADediting_250198	chr11_36486137_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-498-5p	chr11	36486136	36486142	7mer-m8	36486135	36486157	142	-13.5
ADediting_250201	chr11_36486161_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-150-5p	chr11	36486160	36486166	7mer-m8	36486159	36486180	140	-13.49
ADediting_250201	chr11_36486161_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6778-3p	chr11	36486158	36486164	7mer-m8	36486157	36486177	140	-14.63
ADediting_250202	chr11_36486172_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-320e	chr11	36486168	36486174	7mer-m8	36486167	36486184	151	-20.24
ADediting_250202	chr11_36486172_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5089-5p	chr11	36486172	36486178	7mer-m8	36486171	36486194	149	-13.51
ADediting_250202	chr11_36486172_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6506-5p	chr11	36486171	36486177	7mer-m8	36486170	36486196	150	-16.08
ADediting_250203	chr11_36486177_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5089-5p	chr11	36486172	36486178	7mer-m8	36486171	36486194	149	-13.51
ADediting_250203	chr11_36486177_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6504-3p	chr11	36486176	36486182	7mer-m8	36486175	36486195	141	-8.19
ADediting_250204	chr11_36486178_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6504-3p	chr11	36486176	36486182	7mer-m8	36486175	36486195	141	-8.19
ADediting_250204	chr11_36486178_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-7151-3p	chr11	36486177	36486184	8mer-1a	36486177	36486197	146	-15.81
ADediting_250205	chr11_36486200_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4794	chr11	36486199	36486205	7mer-m8	36486198	36486219	140	-12.3
ADediting_250205	chr11_36486200_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-664a-5p	chr11	36486199	36486205	7mer-m8	36486198	36486221	141	-13.02
ADediting_250205	chr11_36486200_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6765-3p	chr11	36486196	36486202	7mer-m8	36486195	36486215	152	-20.77
ADediting_250206	chr11_36486204_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4735-5p	chr11	36486203	36486209	7mer-m8	36486202	36486223	140	-4.28
ADediting_250206	chr11_36486204_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4794	chr11	36486199	36486205	7mer-m8	36486198	36486219	140	-12.3
ADediting_250206	chr11_36486204_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-664a-5p	chr11	36486199	36486205	7mer-m8	36486198	36486221	141	-13.02
ADediting_250207	chr11_36486208_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4735-5p	chr11	36486203	36486209	7mer-m8	36486202	36486223	140	-4.28
ADediting_250213	chr11_36486221_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3976	chr11	36486219	36486226	8mer-1a	36486219	36486242	141	-13.36
ADediting_250214	chr11_36486227_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3170	chr11	36486227	36486233	7mer-m8	36486226	36486247	140	-13.8
ADediting_250214	chr11_36486227_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6855-5p	chr11	36486227	36486233	7mer-m8	36486226	36486250	145	-17.8
ADediting_250214	chr11_36486227_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6890-5p	chr11	36486226	36486232	7mer-m8	36486225	36486245	140	-12.14
ADediting_250215	chr11_36486232_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-193b-5p	chr11	36486227	36486234	8mer-1a	36486227	36486248	142	-14.29
ADediting_250215	chr11_36486232_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3170	chr11	36486227	36486233	7mer-m8	36486226	36486247	140	-13.8
ADediting_250215	chr11_36486232_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6855-5p	chr11	36486227	36486233	7mer-m8	36486226	36486250	145	-17.8
ADediting_250216	chr11_36486233_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-193b-5p	chr11	36486227	36486234	8mer-1a	36486227	36486248	142	-14.29
ADediting_250221	chr11_36486243_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4435	chr11	36486242	36486249	8mer-1a	36486242	36486262	146	-18.85
ADediting_250222	chr11_36486252_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3663-5p	chr11	36486251	36486257	7mer-m8	36486250	36486269	148	-23.23
ADediting_250222	chr11_36486252_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6131	chr11	36486250	36486256	7mer-m8	36486249	36486267	140	-18.33
ADediting_250222	chr11_36486252_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6843-3p	chr11	36486252	36486258	7mer-m8	36486251	36486270	152	-19
ADediting_250222	chr11_36486252_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6848-3p	chr11	36486252	36486258	7mer-m8	36486251	36486268	142	-14.3
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3663-5p	chr11	36486251	36486257	7mer-m8	36486250	36486269	148	-23.23
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6131	chr11	36486250	36486256	7mer-m8	36486249	36486267	140	-18.33
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6843-3p	chr11	36486252	36486258	7mer-m8	36486251	36486270	152	-19
ADediting_250223	chr11_36486255_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6848-3p	chr11	36486252	36486258	7mer-m8	36486251	36486268	142	-14.3
ADediting_250224	chr11_36486257_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6843-3p	chr11	36486252	36486258	7mer-m8	36486251	36486270	152	-19
ADediting_250224	chr11_36486257_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6848-3p	chr11	36486252	36486258	7mer-m8	36486251	36486268	142	-14.3
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-302a-3p	chr11	36486300	36486306	7mer-m8	36486299	36486320	147	-15.15
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-302b-3p	chr11	36486300	36486306	7mer-m8	36486299	36486319	145	-9.46
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-302c-3p	chr11	36486300	36486306	7mer-m8	36486299	36486321	141	-11.96
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-302d-3p	chr11	36486300	36486306	7mer-m8	36486299	36486322	144	-13.56
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-302e	chr11	36486300	36486306	7mer-m8	36486299	36486315	141	-8.62
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-372-3p	chr11	36486300	36486306	7mer-m8	36486299	36486320	155	-19.15
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-512-3p	chr11	36486301	36486307	7mer-m8	36486300	36486326	152	-18.83
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-519d-3p	chr11	36486299	36486305	7mer-m8	36486298	36486318	146	-12.88
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520a-3p	chr11	36486300	36486306	7mer-m8	36486299	36486321	142	-11.03
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520b-3p	chr11	36486300	36486306	7mer-m8	36486299	36486320	144	-14.47
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520c-3p	chr11	36486300	36486306	7mer-m8	36486299	36486319	146	-14.47
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520d-3p	chr11	36486300	36486306	7mer-m8	36486299	36486322	141	-15.12
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520e-3p	chr11	36486300	36486306	7mer-m8	36486299	36486319	143	-13.73
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520g-3p	chr11	36486298	36486304	7mer-m8	36486297	36486321	154	-18.72
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-520h	chr11	36486298	36486304	7mer-m8	36486297	36486319	154	-14.08
ADediting_250229	chr11_36486303_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-526b-3p	chr11	36486299	36486305	7mer-m8	36486298	36486320	149	-15.06
ADediting_250230	chr11_36486306_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5089-5p	chr11	36486306	36486312	7mer-m8	36486305	36486327	148	-14.07
ADediting_250230	chr11_36486306_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-512-3p	chr11	36486301	36486307	7mer-m8	36486300	36486326	152	-18.83
ADediting_250230	chr11_36486306_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6506-5p	chr11	36486305	36486311	7mer-m8	36486304	36486326	140	-13.78
ADediting_250231	chr11_36486311_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5089-5p	chr11	36486306	36486312	7mer-m8	36486305	36486327	148	-14.07
ADediting_250234	chr11_36486320_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6807-5p	chr11	36486320	36486326	7mer-m8	36486319	36486340	143	-19.95
ADediting_250235	chr11_36486826_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6514-3p	chr11	36486826	36486832	7mer-m8	36486825	36486845	155	-17.54
ADediting_250235	chr11_36486826_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6847-3p	chr11	36486821	36486827	7mer-m8	36486820	36486842	153	-22.19
ADediting_250236	chr11_36486830_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6514-3p	chr11	36486826	36486832	7mer-m8	36486825	36486845	155	-17.54
ADediting_250239	chr11_36486845_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-887-5p	chr11	36486844	36486851	8mer-1a	36486844	36486863	143	-13.53
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-30b-3p	chr11	36486845	36486852	8mer-1a	36486845	36486866	151	-16.71
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3689a-3p	chr11	36486845	36486852	8mer-1a	36486845	36486865	147	-22.03
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3689b-3p	chr11	36486845	36486852	8mer-1a	36486845	36486865	147	-20.79
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3689c	chr11	36486845	36486852	8mer-1a	36486845	36486865	147	-20.79
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6779-5p	chr11	36486845	36486852	8mer-1a	36486845	36486863	148	-23.32
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6780a-5p	chr11	36486845	36486852	8mer-1a	36486845	36486868	152	-21.42
ADediting_250240	chr11_36486846_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-887-5p	chr11	36486844	36486851	8mer-1a	36486844	36486863	143	-13.53
ADediting_250241	chr11_36486854_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4478	chr11	36486850	36486856	7mer-m8	36486849	36486865	150	-23.72
ADediting_250241	chr11_36486854_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4649-3p	chr11	36486853	36486859	7mer-m8	36486852	36486872	145	-15.81
ADediting_250241	chr11_36486854_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-485-5p	chr11	36486849	36486855	7mer-m8	36486848	36486870	149	-17.54
ADediting_250241	chr11_36486854_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6765-5p	chr11	36486854	36486860	7mer-m8	36486853	36486877	150	-28.1
ADediting_250241	chr11_36486854_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6884-5p	chr11	36486849	36486855	7mer-m8	36486848	36486869	154	-23.23
ADediting_250241	chr11_36486854_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-7160-5p	chr11	36486852	36486858	7mer-m8	36486851	36486869	154	-22.76
ADediting_250242	chr11_36486870_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-12119	chr11	36486870	36486876	7mer-m8	36486869	36486891	152	-20.09
ADediting_250242	chr11_36486870_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3200-5p	chr11	36486869	36486875	7mer-m8	36486868	36486891	147	-15.85
ADediting_250242	chr11_36486870_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-452-3p	chr11	36486867	36486873	7mer-m8	36486866	36486887	140	-11.83
ADediting_250243	chr11_36486872_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-12119	chr11	36486870	36486876	7mer-m8	36486869	36486891	152	-20.09
ADediting_250243	chr11_36486872_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3200-5p	chr11	36486869	36486875	7mer-m8	36486868	36486891	147	-15.85
ADediting_250243	chr11_36486872_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-452-3p	chr11	36486867	36486873	7mer-m8	36486866	36486887	140	-11.83
ADediting_250243	chr11_36486872_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-7162-3p	chr11	36486870	36486877	8mer-1a	36486870	36486890	142	-19.85
ADediting_250244	chr11_36486884_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3180-5p	chr11	36486884	36486890	7mer-m8	36486883	36486908	154	-17.91
ADediting_250245	chr11_36486897_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-193a-3p	chr11	36486895	36486901	7mer-m8	36486894	36486915	148	-12.65
ADediting_250245	chr11_36486897_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-193b-3p	chr11	36486895	36486901	7mer-m8	36486894	36486915	140	-12.74
ADediting_250245	chr11_36486897_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3190-5p	chr11	36486896	36486902	7mer-m8	36486895	36486913	144	-15.07
ADediting_250245	chr11_36486897_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4463	chr11	36486893	36486899	7mer-m8	36486892	36486910	142	-19.55
ADediting_250245	chr11_36486897_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-548s	chr11	36486897	36486903	7mer-m8	36486896	36486917	143	-12.53
ADediting_250245	chr11_36486897_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-873-3p	chr11	36486892	36486898	7mer-m8	36486891	36486912	146	-15.05
ADediting_250246	chr11_36486904_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5583-3p	chr11	36486902	36486908	7mer-m8	36486901	36486922	148	-14.13
ADediting_250247	chr11_36486906_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-5583-3p	chr11	36486902	36486908	7mer-m8	36486901	36486922	148	-14.13
ADediting_250251	chr11_36486932_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4698	chr11	36486926	36486932	7mer-1a	36486926	36486948	148	-14.27
ADediting_250253	chr11_36486947_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4486	chr11	36486946	36486952	7mer-m8	36486945	36486960	153	-27.8
ADediting_250256	chr11_36486982_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-887-5p	chr11	36486982	36486988	7mer-m8	36486981	36487000	143	-19.73
ADediting_250257	chr11_36486991_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4478	chr11	36486987	36486993	7mer-m8	36486986	36487001	149	-25.05
ADediting_250257	chr11_36486991_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-4649-3p	chr11	36486990	36486996	7mer-m8	36486989	36487009	140	-14.11
ADediting_250257	chr11_36486991_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-7160-5p	chr11	36486989	36486995	7mer-m8	36486988	36487007	149	-18.69
ADediting_250258	chr11_36487004_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-135a-5p	chr11	36487003	36487009	7mer-m8	36487002	36487024	140	-12.68
ADediting_250258	chr11_36487004_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-135b-5p	chr11	36487003	36487009	7mer-m8	36487002	36487024	140	-12.68
ADediting_250259	chr11_36487008_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-135a-5p	chr11	36487003	36487009	7mer-m8	36487002	36487024	140	-12.68
ADediting_250259	chr11_36487008_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-135b-5p	chr11	36487003	36487009	7mer-m8	36487002	36487024	140	-12.68
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-3689d	chr11	36487022	36487028	7mer-1a	36487016	36487036	146	-17.7
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-377-5p	chr11	36487024	36487030	7mer-m8	36487023	36487045	149	-17.66
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6086	chr11	36487024	36487030	7mer-m8	36487023	36487042	150	-23.99
ADediting_250261	chr11_36487028_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6516-5p	chr11	36487028	36487034	7mer-m8	36487027	36487049	148	-14.79
ADediting_250263	chr11_36487058_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6512-3p	chr11	36487058	36487064	7mer-m8	36487057	36487078	140	-19.14
ADediting_250263	chr11_36487058_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6720-5p	chr11	36487058	36487064	7mer-m8	36487057	36487078	144	-21.97
ADediting_250263	chr11_36487058_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-766-3p	chr11	36487057	36487063	7mer-m8	36487056	36487075	153	-25.63
ADediting_250264	chr11_36487077_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-6864-3p	chr11	36487077	36487083	7mer-m8	36487076	36487097	151	-18.93
ADediting_250265	chr11_36487083_-	ENSG00000175104.15	ENST00000526995.6	TRAF6-202	hsa-miR-873-3p	chr11	36487077	36487084	8mer-1a	36487077	36487098	140	-13.18

RNA A-to-I editing in lncRNA gained miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_107020

chr1_37500952_-

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-5581-3p

chr11

36484168

36484174

7mer-m8

36484167

36484187

154

-15.41

ADediting_1337757

chr7_5495852_-

ENSG00000175104.15

ENST00000348124.5

TRAF6-201

hsa-miR-589-3p

chr11

36489537

36489543

7mer-m8

36489536

36489559

162

-21.36

ADediting_1337757

chr7_5495852_-

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-589-3p

chr11

36489537

36489543

7mer-m8

36489536

36489559

162

-21.36

ADediting_291761

chr11_93733708_-

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-1304-3p

chr11

36488358

36488364

7mer-m8

36488357

36488378

156

-19.86

ADediting_843620

chr2_207754818_+

ENSG00000175104.15

ENST00000348124.5

TRAF6-201

hsa-miR-4775

chr11

36489417

36489423

7mer-m8

36489416

36489437

154

-6.24

ADediting_843620

chr2_207754818_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-4775

chr11

36484275

36484281

7mer-m8

36484274

36484297

151

-11.61

ADediting_843620

chr2_207754818_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-4775

chr11

36488814

36488820

7mer-m8

36488813

36488835

141

-11.86

ADediting_843620

chr2_207754818_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-4775

chr11

36489417

36489423

7mer-m8

36489416

36489437

154

-6.24

ADediting_98288

chr1_32086990_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-5585-3p

chr11

36486362

36486368

7mer-m8

36486361

36486385

143

-14.65

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

ADeditom_ID

Position

ENSG

ENST

Transcript name

miRNA ID

Chromosome

Targt

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

ADediting_1097295

chr3_85385762_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-5688

chr11

36488275

36488282

8mer-1a

36488275

36488295

146

-13.49

ADediting_1535953

chr14_101045971_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-381-3p

chr11

36485150

36485157

8mer-1a

36485150

36485174

143

-16.06

ADediting_1535953

chr14_101045971_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-381-3p

chr11

36486403

36486409

7mer-m8

36486402

36486424

147

-18.58

ADediting_1535954

chr14_101045974_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-381-3p

chr11

36485150

36485157

8mer-1a

36485150

36485174

143

-16.06

ADediting_1535954

chr14_101045974_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-381-3p

chr11

36486403

36486409

7mer-m8

36486402

36486424

147

-18.58

ADediting_1556067

chr19_40282625_-

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-641

chr11

36487548

36487554

7mer-m8

36487547

36487570

152

-9.96

ADediting_1631458

chr19_40282624_-

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-641

chr11

36487548

36487554

7mer-m8

36487547

36487570

152

-9.96

ADediting_286380

chr11_79422188_-

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-5579-3p

chr11

36484937

36484944

8mer-1a

36484937

36484958

149

-13.08

ADediting_527135

chr16_24203190_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-1273h-3p

chr11

36485491

36485497

7mer-m8

36485490

36485511

140

-17.85

ADediting_98288

chr1_32086990_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-5585-3p

chr11

36489046

36489052

7mer-m8

36489045

36489066

146

-15.43

ADediting_98289

chr1_32086992_+

ENSG00000175104.15

ENST00000526995.6

TRAF6-202

hsa-miR-5585-3p

chr11

36489046

36489052

7mer-m8

36489045

36489066

146

-15.43

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for TRAF6

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000526995.6	protein_coding

RNA A-to-I editing in miRNA.

ADeditom_ID

ENST

mir_ID

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

RNA A-to-I editing in mRNA.

ADeditom_ID	ENST	Editing_Information	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
ADediting_250192	ENST00000526995.6	chr11_36486067_-	5587	-2357.04	-2356.14	-2399.64
ADediting_250193	ENST00000526995.6	chr11_36486072_-	5582	-2363.04	-2356.14	-2399.64
ADediting_1526741	ENST00000526995.6	chr11_36486086_-	5568	-2355.44	-2356.14	-2399.64
ADediting_1526742	ENST00000526995.6	chr11_36486107_-	5547	-2358.44	-2356.14	-2399.64
ADediting_250194	ENST00000526995.6	chr11_36486108_-	5546	-2362.14	-2356.14	-2399.64
ADediting_250195	ENST00000526995.6	chr11_36486112_-	5542	-2355.24	-2356.14	-2399.64
ADediting_1526743	ENST00000526995.6	chr11_36486116_-	5538	-2355.44	-2356.14	-2399.64
ADediting_250196	ENST00000526995.6	chr11_36486128_-	5526	-2362.74	-2356.14	-2399.64
ADediting_250197	ENST00000526995.6	chr11_36486136_-	5518	-2362.84	-2356.14	-2399.64
ADediting_250198	ENST00000526995.6	chr11_36486137_-	5517	-2355.24	-2356.14	-2399.64
ADediting_250199	ENST00000526995.6	chr11_36486145_-	5509	-2356.14	-2356.14	-2399.64
ADediting_250200	ENST00000526995.6	chr11_36486155_-	5499	-2355.24	-2356.14	-2399.64
ADediting_250201	ENST00000526995.6	chr11_36486161_-	5493	-2355.24	-2356.14	-2399.64
ADediting_250202	ENST00000526995.6	chr11_36486172_-	5482	-2355.44	-2356.14	-2399.64
ADediting_250203	ENST00000526995.6	chr11_36486177_-	5477	-2356.14	-2356.14	-2399.64
ADediting_250204	ENST00000526995.6	chr11_36486178_-	5476	-2356.24	-2356.14	-2399.64
ADediting_1526744	ENST00000526995.6	chr11_36486186_-	5468	-2359.24	-2356.14	-2399.64
ADediting_250205	ENST00000526995.6	chr11_36486200_-	5454	-2360.04	-2356.14	-2399.64
ADediting_250206	ENST00000526995.6	chr11_36486204_-	5450	-2355.84	-2356.14	-2399.64
ADediting_1526745	ENST00000526995.6	chr11_36486207_-	5447	-2356.44	-2356.14	-2399.64
ADediting_250207	ENST00000526995.6	chr11_36486208_-	5446	-2356.54	-2356.14	-2399.64
ADediting_250208	ENST00000526995.6	chr11_36486209_-	5445	-2356.54	-2356.14	-2399.64
ADediting_250209	ENST00000526995.6	chr11_36486210_-	5444	-2356.54	-2356.14	-2399.64
ADediting_250210	ENST00000526995.6	chr11_36486213_-	5441	-2356.14	-2356.14	-2399.64
ADediting_250211	ENST00000526995.6	chr11_36486215_-	5439	-2356.14	-2356.14	-2399.64
ADediting_250212	ENST00000526995.6	chr11_36486216_-	5438	-2356.24	-2356.14	-2399.64
ADediting_1526746	ENST00000526995.6	chr11_36486218_-	5436	-2356.54	-2356.14	-2399.64
ADediting_250213	ENST00000526995.6	chr11_36486221_-	5433	-2354.14	-2356.14	-2399.64
ADediting_250214	ENST00000526995.6	chr11_36486227_-	5427	-2359.84	-2356.14	-2399.64
ADediting_250215	ENST00000526995.6	chr11_36486232_-	5422	-2356.14	-2356.14	-2399.64
ADediting_250216	ENST00000526995.6	chr11_36486233_-	5421	-2356.24	-2356.14	-2399.64
ADediting_250217	ENST00000526995.6	chr11_36486234_-	5420	-2355.64	-2356.14	-2399.64
ADediting_250218	ENST00000526995.6	chr11_36486240_-	5414	-2356.44	-2356.14	-2399.64
ADediting_250219	ENST00000526995.6	chr11_36486241_-	5413	-2356.14	-2356.14	-2399.64
ADediting_250220	ENST00000526995.6	chr11_36486242_-	5412	-2355.84	-2356.14	-2399.64
ADediting_250221	ENST00000526995.6	chr11_36486243_-	5411	-2355.84	-2356.14	-2399.64
ADediting_250222	ENST00000526995.6	chr11_36486252_-	5402	-2355.64	-2356.14	-2399.64
ADediting_250223	ENST00000526995.6	chr11_36486255_-	5399	-2355.54	-2356.14	-2399.64
ADediting_250224	ENST00000526995.6	chr11_36486257_-	5397	-2356.14	-2356.14	-2399.64
ADediting_250225	ENST00000526995.6	chr11_36486263_-	5391	-2355.24	-2356.14	-2399.64
ADediting_250226	ENST00000526995.6	chr11_36486266_-	5388	-2355.44	-2356.14	-2399.64
ADediting_250227	ENST00000526995.6	chr11_36486270_-	5384	-2362.74	-2356.14	-2399.64
ADediting_250228	ENST00000526995.6	chr11_36486271_-	5383	-2355.24	-2356.14	-2399.64
ADediting_250229	ENST00000526995.6	chr11_36486303_-	5351	-2355.74	-2356.14	-2399.64
ADediting_250230	ENST00000526995.6	chr11_36486306_-	5348	-2355.44	-2356.14	-2399.64
ADediting_250231	ENST00000526995.6	chr11_36486311_-	5343	-2356.14	-2356.14	-2399.64
ADediting_250232	ENST00000526995.6	chr11_36486312_-	5342	-2356.24	-2356.14	-2399.64
ADediting_250233	ENST00000526995.6	chr11_36486314_-	5340	-2362.34	-2356.14	-2399.64
ADediting_250234	ENST00000526995.6	chr11_36486320_-	5334	-2356.14	-2356.14	-2399.64
ADediting_1609687	ENST00000526995.6	chr11_36486330_-	5324	-2360.94	-2356.14	-2399.64
ADediting_250235	ENST00000526995.6	chr11_36486826_-	4828	-2361.94	-2356.14	-2399.64
ADediting_250236	ENST00000526995.6	chr11_36486830_-	4824	-2356.14	-2356.14	-2399.64
ADediting_250237	ENST00000526995.6	chr11_36486832_-	4822	-2355.84	-2356.14	-2399.64
ADediting_250238	ENST00000526995.6	chr11_36486844_-	4810	-2355.84	-2356.14	-2399.64
ADediting_250239	ENST00000526995.6	chr11_36486845_-	4809	-2356.24	-2356.14	-2399.64
ADediting_250240	ENST00000526995.6	chr11_36486846_-	4808	-2355.84	-2356.14	-2399.64
ADediting_250241	ENST00000526995.6	chr11_36486854_-	4800	-2358.74	-2356.14	-2399.64
ADediting_250242	ENST00000526995.6	chr11_36486870_-	4784	-2362.34	-2356.14	-2399.64
ADediting_250243	ENST00000526995.6	chr11_36486872_-	4782	-2355.34	-2356.14	-2399.64
ADediting_250244	ENST00000526995.6	chr11_36486884_-	4770	-2356.14	-2356.14	-2399.64
ADediting_250245	ENST00000526995.6	chr11_36486897_-	4757	-2355.44	-2356.14	-2399.64
ADediting_250246	ENST00000526995.6	chr11_36486904_-	4750	-2356.14	-2356.14	-2399.64
ADediting_250247	ENST00000526995.6	chr11_36486906_-	4748	-2355.74	-2356.14	-2399.64
ADediting_250248	ENST00000526995.6	chr11_36486909_-	4745	-2355.74	-2356.14	-2399.64
ADediting_250249	ENST00000526995.6	chr11_36486921_-	4733	-2355.24	-2356.14	-2399.64
ADediting_250250	ENST00000526995.6	chr11_36486923_-	4731	-2355.84	-2356.14	-2399.64
ADediting_250251	ENST00000526995.6	chr11_36486932_-	4722	-2356.14	-2356.14	-2399.64
ADediting_250252	ENST00000526995.6	chr11_36486942_-	4712	-2356.14	-2356.14	-2399.64
ADediting_250253	ENST00000526995.6	chr11_36486947_-	4707	-2360.04	-2356.14	-2399.64
ADediting_250254	ENST00000526995.6	chr11_36486953_-	4701	-2356.44	-2356.14	-2399.64
ADediting_250255	ENST00000526995.6	chr11_36486969_-	4685	-2356.14	-2356.14	-2399.64
ADediting_250256	ENST00000526995.6	chr11_36486982_-	4672	-2355.84	-2356.14	-2399.64
ADediting_250257	ENST00000526995.6	chr11_36486991_-	4663	-2355.44	-2356.14	-2399.64
ADediting_250258	ENST00000526995.6	chr11_36487004_-	4650	-2355.94	-2356.14	-2399.64
ADediting_250259	ENST00000526995.6	chr11_36487008_-	4646	-2355.84	-2356.14	-2399.64
ADediting_250260	ENST00000526995.6	chr11_36487009_-	4645	-2355.84	-2356.14	-2399.64
ADediting_250261	ENST00000526995.6	chr11_36487028_-	4626	-2356.14	-2356.14	-2399.64
ADediting_250262	ENST00000526995.6	chr11_36487034_-	4620	-2355.74	-2356.14	-2399.64
ADediting_250263	ENST00000526995.6	chr11_36487058_-	4596	-2361.24	-2356.14	-2399.64
ADediting_250264	ENST00000526995.6	chr11_36487077_-	4577	-2355.74	-2356.14	-2399.64
ADediting_250265	ENST00000526995.6	chr11_36487083_-	4571	-2355.44	-2356.14	-2399.64

RNA A-to-I editing in lncRNA.

ADeditom_ID

ENST

Editing_Information

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for TRAF6

Correlation between ADAR gene expression and RNA editing frequency

Tissue	ADeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
CER	ADediting_1526741	chr11_36486086_-	0.00189447433888271	0.251638882965336	8.1054512694876e-05	0.316153542587309	0.945271125998954	-0.00565218938599926
CER	ADediting_250194	chr11_36486108_-	8.20010857115773e-11	0.498842179537813	2.61873292945715e-09	0.462187481145778	0.894045792108098	-0.0109660513705235
CER	ADediting_250196	chr11_36486128_-	1.77896080641723e-11	0.513729026822881	6.358504958893e-07	0.393389597513485	0.217167337863239	0.101351638193323
TCX	ADediting_250196	chr11_36486128_-	0.000109805985475301	0.310560226268347	0.0162819189816853	0.195900240380382	0.0249549400048184	0.183048326458509
CER	ADediting_250197	chr11_36486136_-	2.11033147099484e-19	0.650407760995434	1.27173409652169e-13	0.557433464044451	0.00584632450976729	0.224054982252009
TCX	ADediting_250197	chr11_36486136_-	3.74573526410006e-09	0.458140848523879	6.78280496635729e-05	0.31938487699311	0.0209530317648471	0.188399795487704
CER	ADediting_250198	chr11_36486137_-	5.27191186592118e-14	0.56459948501901	5.75593342470299e-11	0.502354481539325	0.00633533932103553	0.22196478794868
TCX	ADediting_250198	chr11_36486137_-	6.14675713272156e-09	0.452452663971956	0.000772244825496514	0.271642744494128	0.000761916908547711	0.271931519980544
CER	ADediting_250199	chr11_36486145_-	4.86646603923107e-14	0.565242265871564	2.07405617752606e-13	0.553377594464709	0.0550221626567491	0.157001702890678
TCX	ADediting_250199	chr11_36486145_-	0.00023453751095212	0.296068935917059	2.89831559308573e-06	0.371309859156152	0.237092470910591	-0.0971172564336974
CER	ADediting_250204	chr11_36486178_-	2.12687428849077e-08	0.437721820875519	4.93292920616289e-09	0.454991949795269	0.0737279705137937	0.146450720239241
CER	ADediting_250205	chr11_36486200_-	1.28124946679964e-05	0.347973051830376	3.35415967936089e-05	0.331811318361962	0.380819040653637	0.0720665653912773
CER	ADediting_250209	chr11_36486210_-	0.00455956783038899	0.230410775887266	0.0196199514837689	0.190379133814342	9.79939035513774e-05	0.312670049347784
CER	ADediting_250210	chr11_36486213_-	2.0650690990675e-07	0.408782318065483	5.28136961545335e-08	0.426465713907556	0.0870639590525321	0.140192103166161
CER	ADediting_250214	chr11_36486227_-	5.62015382808124e-09	0.453488994526123	1.95230680925367e-05	0.341010016683221	0.0113328683230453	0.206255777784709
STG	ADediting_250214	chr11_36486227_-	3.67408304489112e-05	0.434253262368755	0.0171274364445152	0.259526459540715	0.473998867278325	0.0791843741145396
CER	ADediting_250215	chr11_36486232_-	4.22189919620676e-12	0.527111920096439	1.76443105558523e-12	0.534953212502687	0.00559594075207539	0.22518631688252
CER	ADediting_250218	chr11_36486240_-	3.12592106297669e-05	0.333025820630965	0.00033923674935898	0.288736622043887	0.925533081158669	0.00769576137820281
CER	ADediting_250219	chr11_36486241_-	5.16718297929309e-06	0.362447907617768	9.84855644868886e-06	0.35224024167449	0.00162742999147682	0.255136374995169
CER	ADediting_250220	chr11_36486242_-	3.09269047488339e-08	0.433137967700078	1.58422203552827e-10	0.492198734743161	0.0255437455594222	0.182324274513288
CER	ADediting_250221	chr11_36486243_-	0.000429863000454814	0.283926859105701	2.6222438513757e-05	0.336031737898733	0.0111007869246208	0.206833189655483
CER	ADediting_250222	chr11_36486252_-	8.28404351102813e-05	0.315755680330849	2.0619911065632e-06	0.376407910681156	0.381160755037836	0.0720150079239373
CER	ADediting_250224	chr11_36486257_-	0.000160573977516141	0.303397683856483	0.000354161548376967	0.28786831328278	0.382052713649759	0.0718805624241686
CER	ADediting_250226	chr11_36486266_-	3.46905541238714e-05	0.331229057066995	7.46119686268807e-09	0.450198472046548	0.0936506194480572	0.137380788898066
CER	ADediting_250227	chr11_36486270_-	1.08298592407142e-16	0.610557995441832	3.32779186263225e-15	0.586019118758856	0.0136406078749465	0.201017737553604
TCX	ADediting_250227	chr11_36486270_-	2.45639335154026e-07	0.406457159780995	0.00170403960858143	0.254082546154247	0.048092584184371	0.161673728307888
STG	ADediting_250227	chr11_36486270_-	0.0684312718479763	0.199797565882821	0.00199864549630798	0.332525733823303	0.0751735452851812	-0.195201475644745
CER	ADediting_250230	chr11_36486306_-	6.00452098551503e-09	0.452723889105624	4.28296625195851e-09	0.456611899015092	0.208624183839812	0.103251938410654
CER	ADediting_250231	chr11_36486311_-	2.33527237557665e-08	0.436583688115836	5.21128615447732e-05	0.324099237063115	0.00217276520943419	0.248442222508045
TCX	ADediting_250231	chr11_36486311_-	2.62424431651762e-13	0.551406882431888	0.000992491843222051	0.266202460527894	2.85968223244874e-05	0.334552683154213
CER	ADediting_250232	chr11_36486312_-	5.93037834615214e-07	0.394366541855137	0.000145163869604083	0.305317143743086	0.0128276547726318	0.202767645940432
TCX	ADediting_250232	chr11_36486312_-	3.49949649552022e-09	0.458913691179697	0.00278790054795941	0.242522354382365	0.0127544106880917	0.202930035510744
CER	ADediting_250233	chr11_36486314_-	8.57255641255611e-16	0.595987793779258	1.30693359907138e-11	0.51664759692046	0.00621800605898719	0.222452837845105
TCX	ADediting_250233	chr11_36486314_-	4.66573548786473e-15	0.58348127263371	3.75407859974264e-07	0.400698527504114	0.000329080647106137	0.289347955950818
CER	ADediting_250235	chr11_36486826_-	6.74295656055782e-07	0.392564383670716	1.17183354073505e-06	0.384683850524535	0.0351372401494976	0.17217091512005
CER	ADediting_250237	chr11_36486832_-	7.50653659387259e-07	0.39105061128036	8.18491402645714e-07	0.389824228878334	0.303511585478627	0.084568803532757
TCX	ADediting_250237	chr11_36486832_-	4.59143257669866e-05	0.326336966011858	0.00107760529719895	0.264393723975281	0.17335143867362	0.111753436866011
TCX	ADediting_250238	chr11_36486844_-	0.000573409143708158	0.277955632338555	0.820446087884546	0.0186868317728329	1.41034528347607e-05	0.346400473597629
CER	ADediting_250241	chr11_36486854_-	3.4078723096467e-06	0.368853925542966	5.58878849824815e-08	0.425751811824802	0.0558904411034787	0.156451171814635
CER	ADediting_250243	chr11_36486872_-	6.84878573530363e-15	0.580571836068677	1.47533873444423e-12	0.536536808531499	0.0176737864346123	0.193488639141816
TCX	ADediting_250243	chr11_36486872_-	2.11629473336084e-05	0.339657447436349	0.102520473144989	0.13383304822526	0.0109206290671636	0.207288781344482
CER	ADediting_250245	chr11_36486897_-	7.10184875970457e-09	0.450774193856947	1.22654409680445e-09	0.470592476785923	0.148259404352427	0.118616607972799
CER	ADediting_250246	chr11_36486904_-	6.02805996669923e-15	0.58154261702999	4.89432069426928e-10	0.480477476294569	0.0131083330304233	0.202152778186238
TCX	ADediting_250246	chr11_36486904_-	7.26925906768752e-07	0.391504646419017	0.118525136554851	0.128000553546112	0.000250877278824016	0.29474552292606
CER	ADediting_250248	chr11_36486909_-	3.90055834284343e-05	0.32919309320973	9.61973882915919e-06	0.352618525087344	0.338239859417932	0.0787288561326138
CER	ADediting_250253	chr11_36486947_-	3.04477941600581e-07	0.403555270818135	6.35747690961238e-07	0.393391867345036	0.203781621662409	0.104353976692453
CER	ADediting_250255	chr11_36486969_-	0.00010979954021911	0.310561318519644	0.000619163889539373	0.276341953044623	0.915349054308584	0.00875192052468222
CER	ADediting_250257	chr11_36486991_-	1.13684255620274e-11	0.517958276777116	1.80178467785664e-08	0.439731255931059	0.0805772809680638	0.1431320582383
TCX	ADediting_250257	chr11_36486991_-	1.73359926471497e-07	0.411108981740115	0.0005105981678211	0.280375926022784	0.0216788974774311	0.18736732464343
IFG	ADediting_250257	chr11_36486991_-	0.53542340931557	0.130080897172924	0.869155207592047	0.0347136948646943	0.0248309770456941	0.44767372473998
CER	ADediting_250258	chr11_36487004_-	1.05197493720627e-06	0.386238610916908	2.08522391221602e-07	0.408652642816879	0.125856778863782	0.125531986216071
CER	ADediting_250259	chr11_36487008_-	1.26684664582741e-09	0.470238818159897	2.03436795703431e-07	0.408982193254827	0.0126832935622853	0.203088492950368
TCX	ADediting_250259	chr11_36487008_-	4.18116042633244e-07	0.399218235837523	0.0454874948731302	0.163575679022908	6.80224312502048e-05	0.319333259176436
CER	ADediting_250260	chr11_36487009_-	1.43000572606133e-10	0.493241336528993	5.29448510857221e-09	0.454177768516352	0.642015301031682	0.0382637194485809
TCX	ADediting_250260	chr11_36487009_-	7.49876450696612e-07	0.391065265182124	0.0803508553760884	0.143238063514157	9.35271462051352e-05	0.313530372739425
IFG	ADediting_250260	chr11_36487009_-	0.191671475469444	0.27007266264822	0.359575326020351	0.191329491472244	0.00062032152483321	0.636770242415562
CER	ADediting_250263	chr11_36487058_-	1.32599596533234e-06	0.382893086098057	0.0001392061974156	0.306110555171759	0.0718732914692461	0.147392108990864
TCX	ADediting_250263	chr11_36487058_-	0.00012702272473555	0.307836800713896	0.223414384902273	0.0999955283191257	0.0007471972067949	0.272349372648455

Correlation between ADAR gene expression and this gene's expression

Tissue	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
DLPFC	1.50808384960182e-70	0.80082281048745	3.35871393520435e-41	0.666626520458596	1.53291656181057e-10	0.353250241416176
AC	1.22609531636729e-53	0.785656816885594	8.14916182564809e-32	0.653345624482426	1.60855841933475e-19	0.530138356973915
PCC	5.10817346842184e-28	0.687062549892617	5.15609599659368e-24	0.646772304253214	6.46858198693508e-07	0.350887186864964
CER	7.13768386591888e-35	0.801556916002725	2.09728062980817e-29	0.759267941421592	0.0028045425563049	0.242379301962484
TCX	3.0079993562804e-33	0.78995424870532	3.55601926365255e-06	0.36820528714258	3.4536209150727e-12	0.528935131856025
FP	5.15011030595129e-40	0.794740180023616	2.23363806514222e-23	0.657169559372274	8.30034654050374e-08	0.388617021162117
IFG	6.05468677079036e-09	0.881217762422854	7.12514748455068e-06	0.768829954424713	0.00596474928677334	0.534039482967084
PG	2.43033810207763e-60	0.876570173476782	1.64937301823597e-25	0.669138746123086	0.152865882019501	0.105232825917062
STG	5.13105943132729e-17	0.760056700535932	3.55098266945407e-08	0.557781024104085	0.160134686832604	0.15464999350433

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Relation with AD stages for TRAF6

Correlation between AD stages and RNA editing frequency

Tissue	ADeditomID	position	P-val	Coeff.
CER	ADediting_250197	chr11_36486136_-	0.00154461500662456	0.301066655293863
CER	ADediting_250198	chr11_36486137_-	0.000329521724638129	0.3391808464635
CER	ADediting_250243	chr11_36486872_-	0.000333222231286349	0.338922312734345
TCX	ADediting_250196	chr11_36486128_-	0.000729802187280173	0.323097534417499
TCX	ADediting_250197	chr11_36486136_-	0.000206858868526679	0.352911034370119
TCX	ADediting_250198	chr11_36486137_-	0.000648967414498611	0.326003329872292
TCX	ADediting_250210	chr11_36486213_-	0.000606384986319984	0.327670282361773
TCX	ADediting_250227	chr11_36486270_-	0.00048748394333372	0.332968275570662
TCX	ADediting_250231	chr11_36486311_-	4.98098766679813e-05	0.383384612212574
TCX	ADediting_250232	chr11_36486312_-	0.000923375416060654	0.317186020224459
TCX	ADediting_250233	chr11_36486314_-	0.000413344148227824	0.33691108721108
TCX	ADediting_250238	chr11_36486844_-	1.2277304415912e-05	0.410681145297535
TCX	ADediting_250243	chr11_36486872_-	0.00122631882390129	0.309893427824386
TCX	ADediting_250246	chr11_36486904_-	0.000400513553066145	0.337658791307364
TCX	ADediting_250257	chr11_36486991_-	6.5192885118303e-06	0.422276381915419
TCX	ADediting_250259	chr11_36487008_-	2.79293749028043e-07	0.474369076170092
TCX	ADediting_250260	chr11_36487009_-	2.33359596918471e-06	0.440229187421369
TCX	ADediting_250263	chr11_36487058_-	4.38551898245306e-05	0.385967829991013
IFG	ADediting_250197	chr11_36486136_-	0.0194082719008794	0.464205054464747
IFG	ADediting_250198	chr11_36486137_-	0.0289810327922212	0.43689887479035

Correlation between AD stages and this gene's expression

Tissue	P-val	Coeff.
CER	2.19060754896752e-05	0.39619569935308
TCX	2.40781463491222e-10	0.566736562750292

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RelatedDrugs for TRAF6

Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for TRAF6

Diseases associated with this gene.
(DisGeNet 4.0)

Gene	Disease ID	Disease name	# pubmeds	Source
TRAF6	C0003873	Rheumatoid Arthritis	2	CTD_human
TRAF6	C0010054	Coronary Arteriosclerosis	1	CTD_human
TRAF6	C1956346	Coronary Artery Disease	1	CTD_human

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Gene summary for TRAF6

RNA A-to-I events for TRAF6

RNA editing positional annotations for TRAF6 using Annovar

RNA A-to-I editing events in the alternative splicing sites for TRAF6

Differntial gene expression between RNA A-to-I edited versus non-edited samples for TRAF6

Protein coding region RNA A-to-I editings for TRAF6

The effects of the RNA editing to the miRNA binding sites for TRAF6

The effects of the RNA editing to the stability of the RNA structures for TRAF6

Relation with ADAR for TRAF6

Relation with AD stages for TRAF6

RelatedDrugs for TRAF6

RelatedDiseases for TRAF6

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited versus non-edited samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with AD stages
	Related drugs with this gene
	Related diseases with this gene