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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for TRAF2

check button Gene summary
Gene informationGene symbol

TRAF2

Gene ID

7186

Gene nameTNF receptor associated factor 2
SynonymsMGC:45012|RNF117|TRAP|TRAP3
Cytomap

9q34.3

Type of geneprotein-coding
DescriptionTNF receptor-associated factor 2E3 ubiquitin-protein ligase TRAF2RING-type E3 ubiquitin transferase TRAF2tumor necrosis factor type 2 receptor associated protein 3
Modification date20200327
UniProtAcc

Q12933,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
TRAF2

GO:0033209

tumor necrosis factor-mediated signaling pathway

11907583

TRAF2

GO:0042981

regulation of apoptotic process

11907583

TRAF2

GO:0043507

positive regulation of JUN kinase activity

11907583

TRAF2

GO:0051092

positive regulation of NF-kappaB transcription factor activity

11279055

TRAF2

GO:0051865

protein autoubiquitination

20577214

TRAF2

GO:0070534

protein K63-linked ubiquitination

15258597|20577214


Top

RNA A-to-I events for TRAF2

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1455363(136887894, +), ADediting_1455364(136887913, +), ADediting_1455365(136887925, +), ADediting_1455366(136887944, +), ADediting_1455367(136887949, +), ADediting_1455368(136887970, +), ADediting_1455369(136887974, +), ADediting_1455370(136887987, +), ADediting_1455371(136887999, +), ADediting_1455372(136888009, +), ADediting_1455373(136888310, +), ADediting_1455374(136888316, +), ADediting_1455375(136888320, +), ADediting_1455376(136888337, +), ADediting_1455377(136888381, +), ADediting_1455378(136888383, +), ADediting_1455379(136888927, +), ADediting_1455380(136888995, +), ADediting_1455381(136889306, +), ADediting_1455382(136889377, +), ADediting_1455383(136889413, +), ADediting_1455384(136890971, +), ADediting_1455385(136890984, +), ADediting_1455386(136891030, +), ADediting_1455387(136891047, +), ADediting_1455388(136891057, +), ADediting_1455389(136891075, +), ADediting_1455390(136891134, +), ADediting_1455391(136891170, +), ADediting_1455392(136891178, +), ADediting_1455393(136891189, +), ADediting_1455394(136891226, +), ADediting_1455395(136891238, +), ADediting_1455396(136891284, +), ADediting_1455397(136891307, +), ADediting_1455398(136891310, +), ADediting_1455399(136891319, +), ADediting_1455400(136891344, +), ADediting_1455401(136891370, +), ADediting_1455402(136891382, +), ADediting_1455403(136891385, +), ADediting_1455404(136891433, +), ADediting_1455405(136891444, +), ADediting_1455406(136891453, +), ADediting_1455407(136891478, +), ADediting_1455408(136891479, +), ADediting_1455409(136891483, +), ADediting_1455410(136891766, +), ADediting_1455411(136891802, +), ADediting_1455412(136891821, +), ADediting_1455413(136891822, +), ADediting_1455414(136891839, +), ADediting_1455415(136891847, +), ADediting_1455416(136891851, +), ADediting_1455417(136891861, +), ADediting_1455418(136891863, +), ADediting_1455419(136891901, +), ADediting_1455420(136891904, +), ADediting_1455421(136891907, +), ADediting_1455422(136891920, +), ADediting_1455423(136891930, +), ADediting_1455424(136891961, +), ADediting_1455425(136891970, +), ADediting_1455426(136891979, +), ADediting_1455427(136891980, +), ADediting_1455428(136891992, +), ADediting_1455429(136891998, +), ADediting_1455430(136892186, +), ADediting_1455431(136892208, +), ADediting_1455432(136892209, +), ADediting_1455433(136892304, +), ADediting_1455434(136892310, +), ADediting_1455435(136892317, +), ADediting_1455436(136892343, +), ADediting_1455437(136892349, +), ADediting_1455438(136892353, +), ADediting_1455439(136892370, +), ADediting_1455440(136892384, +), ADediting_1455441(136892414, +), ADediting_1455442(136892608, +), ADediting_1455443(136892622, +), ADediting_1455444(136892624, +), ADediting_1455445(136892625, +), ADediting_1455446(136892655, +), ADediting_1455447(136892660, +), ADediting_1455448(136892670, +), ADediting_1455449(136892694, +), ADediting_1455450(136892703, +), ADediting_1455451(136892718, +), ADediting_1455452(136892720, +), ADediting_1455453(136892721, +), ADediting_1455454(136892733, +), ADediting_1455455(136892759, +), ADediting_1455456(136892760, +), ADediting_1455457(136892769, +), ADediting_1455458(136892786, +), ADediting_1455459(136892792, +), ADediting_1455460(136892801, +), ADediting_1455461(136892831, +), ADediting_1455462(136892833, +), ADediting_1455463(136893849, +), ADediting_1455464(136893850, +), ADediting_1455465(136893867, +), ADediting_1455466(136893879, +), ADediting_1455467(136893970, +), ADediting_1455468(136894010, +), ADediting_1455469(136894108, +), ADediting_1455470(136894126, +), ADediting_1455471(136894127, +), ADediting_1455472(136894147, +), ADediting_1455473(136894150, +), ADediting_1455474(136894151, +), ADediting_1455475(136894176, +), ADediting_1455476(136894236, +), ADediting_1455477(136894247, +), ADediting_1455478(136894307, +), ADediting_1455479(136894319, +), ADediting_1455480(136894321, +), ADediting_1455481(136894337, +), ADediting_1455482(136894474, +), ADediting_1455483(136894839, +), ADediting_1455484(136895581, +), ADediting_1455485(136895593, +), ADediting_1455486(136895599, +), ADediting_1455487(136895600, +), ADediting_1455488(136895637, +), ADediting_1455489(136895642, +), ADediting_1455490(136895650, +), ADediting_1455491(136895651, +), ADediting_1455492(136895656, +), ADediting_1455493(136895665, +), ADediting_1455494(136895666, +), ADediting_1455495(136895689, +), ADediting_1455496(136895695, +), ADediting_1455497(136895697, +), ADediting_1455498(136895699, +), ADediting_1455499(136895702, +), ADediting_1455500(136895722, +), ADediting_1455501(136895738, +), ADediting_1455502(136895761, +), ADediting_1455503(136895770, +), ADediting_1455504(136895774, +), ADediting_1455505(136895811, +), ADediting_1455506(136895821, +), ADediting_1455507(136896694, +), ADediting_1455508(136896738, +), ADediting_1455509(136896748, +), ADediting_1455510(136896750, +), ADediting_1455511(136896815, +), ADediting_1455512(136896819, +), ADediting_1455513(136896822, +), ADediting_1455514(136896870, +), ADediting_1455515(136896877, +), ADediting_1455516(136903123, +), ADediting_1455517(136903134, +), ADediting_1455518(136903233, +), ADediting_1455519(136904437, +), ADediting_1455520(136904539, +), ADediting_1455521(136905998, +), ADediting_1455522(136906011, +), ADediting_1455523(136908763, +), ADediting_1455524(136908771, +), ADediting_1455525(136908795, +), ADediting_1455526(136911321, +), ADediting_1455527(136911345, +), ADediting_1455528(136911364, +), ADediting_1455529(136911382, +), ADediting_1455530(136911394, +), ADediting_1455531(136911422, +), ADediting_1455532(136912279, +), ADediting_1455533(136912434, +), ADediting_1455534(136912598, +), ADediting_1455535(136912660, +), ADediting_1455536(136912681, +), ADediting_1455537(136912690, +), ADediting_1455538(136912716, +), ADediting_1455539(136912747, +), ADediting_1455540(136912895, +), ADediting_1455541(136912899, +), ADediting_1455542(136912904, +), ADediting_1455543(136912931, +), ADediting_1455544(136912954, +), ADediting_1455545(136912955, +), ADediting_1455546(136912990, +), ADediting_1455547(136913017, +), ADediting_1455548(136913397, +), ADediting_1455549(136913398, +), ADediting_1455550(136913415, +), ADediting_1455551(136913559, +), ADediting_1455552(136924346, +), ADediting_1455553(136924378, +), ADediting_1455554(136924406, +), ADediting_1455555(136924463, +), ADediting_1455556(136924801, +), ADediting_1455557(136924820, +), ADediting_1593117(136888054, +), ADediting_1593118(136888060, +), ADediting_1593119(136888080, +), ADediting_1593120(136888091, +), ADediting_1593121(136888391, +), ADediting_1593122(136891506, +), ADediting_1593123(136891518, +), ADediting_1593124(136891534, +), ADediting_1593125(136891815, +), ADediting_1593126(136891848, +), ADediting_1593127(136892405, +), ADediting_1593128(136892791, +), ADediting_1593129(136893889, +), ADediting_1593130(136893950, +), ADediting_1593131(136894022, +), ADediting_1593132(136894188, +), ADediting_1593133(136894230, +), ADediting_1593134(136894244, +), ADediting_1593135(136895676, +), ADediting_1593136(136895681, +), ADediting_1593137(136895698, +), ADediting_1593138(136896661, +), ADediting_1593139(136896807, +), ADediting_1593140(136903125, +), ADediting_1593141(136905772, +), ADediting_1593142(136912971, +),

Top

RNA editing positional annotations for TRAF2 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1455363chr9_136887894_+intronic
ADediting_1455364chr9_136887913_+intronic
ADediting_1455365chr9_136887925_+intronic
ADediting_1455366chr9_136887944_+intronic
ADediting_1455367chr9_136887949_+intronic
ADediting_1455368chr9_136887970_+intronic
ADediting_1455369chr9_136887974_+intronic
ADediting_1455370chr9_136887987_+intronic
ADediting_1455371chr9_136887999_+intronic
ADediting_1455372chr9_136888009_+intronic
ADediting_1455373chr9_136888310_+intronic
ADediting_1455374chr9_136888316_+intronic
ADediting_1455375chr9_136888320_+intronic
ADediting_1455376chr9_136888337_+intronic
ADediting_1455377chr9_136888381_+intronic
ADediting_1455378chr9_136888383_+intronic
ADediting_1455379chr9_136888927_+intronic
ADediting_1455380chr9_136888995_+intronic
ADediting_1455381chr9_136889306_+intronic
ADediting_1455382chr9_136889377_+intronic
ADediting_1455383chr9_136889413_+intronic
ADediting_1455384chr9_136890971_+intronic
ADediting_1455385chr9_136890984_+intronic
ADediting_1455386chr9_136891030_+intronic
ADediting_1455387chr9_136891047_+intronic
ADediting_1455388chr9_136891057_+intronic
ADediting_1455389chr9_136891075_+intronic
ADediting_1455390chr9_136891134_+intronic
ADediting_1455391chr9_136891170_+intronic
ADediting_1455392chr9_136891178_+intronic
ADediting_1455393chr9_136891189_+intronic
ADediting_1455394chr9_136891226_+intronic
ADediting_1455395chr9_136891238_+intronic
ADediting_1455396chr9_136891284_+intronic
ADediting_1455397chr9_136891307_+intronic
ADediting_1455398chr9_136891310_+intronic
ADediting_1455399chr9_136891319_+intronic
ADediting_1455400chr9_136891344_+intronic
ADediting_1455401chr9_136891370_+intronic
ADediting_1455402chr9_136891382_+intronic
ADediting_1455403chr9_136891385_+intronic
ADediting_1455404chr9_136891433_+intronic
ADediting_1455405chr9_136891444_+intronic
ADediting_1455406chr9_136891453_+intronic
ADediting_1455407chr9_136891478_+intronic
ADediting_1455408chr9_136891479_+intronic
ADediting_1455409chr9_136891483_+intronic
ADediting_1455410chr9_136891766_+intronic
ADediting_1455411chr9_136891802_+intronic
ADediting_1455412chr9_136891821_+intronic
ADediting_1455413chr9_136891822_+intronic
ADediting_1455414chr9_136891839_+intronic
ADediting_1455415chr9_136891847_+intronic
ADediting_1455416chr9_136891851_+intronic
ADediting_1455417chr9_136891861_+intronic
ADediting_1455418chr9_136891863_+intronic
ADediting_1455419chr9_136891901_+intronic
ADediting_1455420chr9_136891904_+intronic
ADediting_1455421chr9_136891907_+intronic
ADediting_1455422chr9_136891920_+intronic
ADediting_1455423chr9_136891930_+intronic
ADediting_1455424chr9_136891961_+intronic
ADediting_1455425chr9_136891970_+intronic
ADediting_1455426chr9_136891979_+intronic
ADediting_1455427chr9_136891980_+intronic
ADediting_1455428chr9_136891992_+intronic
ADediting_1455429chr9_136891998_+intronic
ADediting_1455430chr9_136892186_+intronic
ADediting_1455431chr9_136892208_+intronic
ADediting_1455432chr9_136892209_+intronic
ADediting_1455433chr9_136892304_+intronic
ADediting_1455434chr9_136892310_+intronic
ADediting_1455435chr9_136892317_+intronic
ADediting_1455436chr9_136892343_+intronic
ADediting_1455437chr9_136892349_+intronic
ADediting_1455438chr9_136892353_+intronic
ADediting_1455439chr9_136892370_+intronic
ADediting_1455440chr9_136892384_+intronic
ADediting_1455441chr9_136892414_+intronic
ADediting_1455442chr9_136892608_+intronic
ADediting_1455443chr9_136892622_+intronic
ADediting_1455444chr9_136892624_+intronic
ADediting_1455445chr9_136892625_+intronic
ADediting_1455446chr9_136892655_+intronic
ADediting_1455447chr9_136892660_+intronic
ADediting_1455448chr9_136892670_+intronic
ADediting_1455449chr9_136892694_+intronic
ADediting_1455450chr9_136892703_+intronic
ADediting_1455451chr9_136892718_+intronic
ADediting_1455452chr9_136892720_+intronic
ADediting_1455453chr9_136892721_+intronic
ADediting_1455454chr9_136892733_+intronic
ADediting_1455455chr9_136892759_+intronic
ADediting_1455456chr9_136892760_+intronic
ADediting_1455457chr9_136892769_+intronic
ADediting_1455458chr9_136892786_+intronic
ADediting_1455459chr9_136892792_+intronic
ADediting_1455460chr9_136892801_+intronic
ADediting_1455461chr9_136892831_+intronic
ADediting_1455462chr9_136892833_+intronic
ADediting_1455463chr9_136893849_+intronic
ADediting_1455464chr9_136893850_+intronic
ADediting_1455465chr9_136893867_+intronic
ADediting_1455466chr9_136893879_+intronic
ADediting_1455467chr9_136893970_+intronic
ADediting_1455468chr9_136894010_+intronic
ADediting_1455469chr9_136894108_+intronic
ADediting_1455470chr9_136894126_+intronic
ADediting_1455471chr9_136894127_+intronic
ADediting_1455472chr9_136894147_+intronic
ADediting_1455473chr9_136894150_+intronic
ADediting_1455474chr9_136894151_+intronic
ADediting_1455475chr9_136894176_+intronic
ADediting_1455476chr9_136894236_+intronic
ADediting_1455477chr9_136894247_+intronic
ADediting_1455478chr9_136894307_+intronic
ADediting_1455479chr9_136894319_+intronic
ADediting_1455480chr9_136894321_+intronic
ADediting_1455481chr9_136894337_+intronic
ADediting_1455482chr9_136894474_+intronic
ADediting_1455483chr9_136894839_+intronic
ADediting_1455484chr9_136895581_+intronic
ADediting_1455485chr9_136895593_+intronic
ADediting_1455486chr9_136895599_+intronic
ADediting_1455487chr9_136895600_+intronic
ADediting_1455488chr9_136895637_+intronic
ADediting_1455489chr9_136895642_+intronic
ADediting_1455490chr9_136895650_+intronic
ADediting_1455491chr9_136895651_+intronic
ADediting_1455492chr9_136895656_+intronic
ADediting_1455493chr9_136895665_+intronic
ADediting_1455494chr9_136895666_+intronic
ADediting_1455495chr9_136895689_+intronic
ADediting_1455496chr9_136895695_+intronic
ADediting_1455497chr9_136895697_+intronic
ADediting_1455498chr9_136895699_+intronic
ADediting_1455499chr9_136895702_+intronic
ADediting_1455500chr9_136895722_+intronic
ADediting_1455501chr9_136895738_+intronic
ADediting_1455502chr9_136895761_+intronic
ADediting_1455503chr9_136895770_+intronic
ADediting_1455504chr9_136895774_+intronic
ADediting_1455505chr9_136895811_+intronic
ADediting_1455506chr9_136895821_+intronic
ADediting_1455507chr9_136896694_+intronic
ADediting_1455508chr9_136896738_+intronic
ADediting_1455509chr9_136896748_+intronic
ADediting_1455510chr9_136896750_+intronic
ADediting_1455511chr9_136896815_+intronic
ADediting_1455512chr9_136896819_+intronic
ADediting_1455513chr9_136896822_+intronic
ADediting_1455514chr9_136896870_+intronic
ADediting_1455515chr9_136896877_+intronic
ADediting_1455516chr9_136903123_+intronic
ADediting_1455517chr9_136903134_+intronic
ADediting_1455518chr9_136903233_+intronic
ADediting_1455519chr9_136904437_+intronic
ADediting_1455520chr9_136904539_+intronic
ADediting_1455521chr9_136905998_+intronic
ADediting_1455522chr9_136906011_+intronic
ADediting_1455523chr9_136908763_+intronic
ADediting_1455524chr9_136908771_+intronic
ADediting_1455525chr9_136908795_+intronic
ADediting_1455526chr9_136911321_+intronic
ADediting_1455527chr9_136911345_+intronic
ADediting_1455528chr9_136911364_+intronic
ADediting_1455529chr9_136911382_+intronic
ADediting_1455530chr9_136911394_+intronic
ADediting_1455531chr9_136911422_+intronic
ADediting_1455532chr9_136912279_+intronic
ADediting_1455533chr9_136912434_+intronic
ADediting_1455534chr9_136912598_+intronic
ADediting_1455535chr9_136912660_+intronic
ADediting_1455536chr9_136912681_+intronic
ADediting_1455537chr9_136912690_+intronic
ADediting_1455538chr9_136912716_+intronic
ADediting_1455539chr9_136912747_+intronic
ADediting_1455540chr9_136912895_+intronic
ADediting_1455541chr9_136912899_+intronic
ADediting_1455542chr9_136912904_+intronic
ADediting_1455543chr9_136912931_+intronic
ADediting_1455544chr9_136912954_+intronic
ADediting_1455545chr9_136912955_+intronic
ADediting_1455546chr9_136912990_+intronic
ADediting_1455547chr9_136913017_+intronic
ADediting_1455548chr9_136913397_+intronic
ADediting_1455549chr9_136913398_+intronic
ADediting_1455550chr9_136913415_+intronic
ADediting_1455551chr9_136913559_+intronic
ADediting_1455552chr9_136924346_+intronic
ADediting_1455553chr9_136924378_+intronic
ADediting_1455554chr9_136924406_+intronic
ADediting_1455555chr9_136924463_+intronic
ADediting_1455556chr9_136924801_+intronic
ADediting_1455557chr9_136924820_+intronic
ADediting_1593117chr9_136888054_+intronic
ADediting_1593118chr9_136888060_+intronic
ADediting_1593119chr9_136888080_+intronic
ADediting_1593120chr9_136888091_+intronic
ADediting_1593121chr9_136888391_+intronic
ADediting_1593122chr9_136891506_+intronic
ADediting_1593123chr9_136891518_+intronic
ADediting_1593124chr9_136891534_+intronic
ADediting_1593125chr9_136891815_+intronic
ADediting_1593126chr9_136891848_+intronic
ADediting_1593127chr9_136892405_+intronic
ADediting_1593128chr9_136892791_+intronic
ADediting_1593129chr9_136893889_+intronic
ADediting_1593130chr9_136893950_+intronic
ADediting_1593131chr9_136894022_+intronic
ADediting_1593132chr9_136894188_+intronic
ADediting_1593133chr9_136894230_+intronic
ADediting_1593134chr9_136894244_+intronic
ADediting_1593135chr9_136895676_+intronic
ADediting_1593136chr9_136895681_+intronic
ADediting_1593137chr9_136895698_+intronic
ADediting_1593138chr9_136896661_+intronic
ADediting_1593139chr9_136896807_+intronic
ADediting_1593140chr9_136903125_+intronic
ADediting_1593141chr9_136905772_+intronic
ADediting_1593142chr9_136912971_+intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1455363chr9_136887894_+SINEAluName=AluSq
ADediting_1455364chr9_136887913_+SINEAluName=AluSq
ADediting_1455365chr9_136887925_+SINEAluName=AluSq
ADediting_1455366chr9_136887944_+SINEAluName=AluSq
ADediting_1455367chr9_136887949_+SINEAluName=AluSq
ADediting_1455368chr9_136887970_+SINEAluName=AluSq
ADediting_1455369chr9_136887974_+SINEAluName=AluSq
ADediting_1455370chr9_136887987_+SINEAluName=AluSq
ADediting_1455371chr9_136887999_+SINEAluName=AluSq
ADediting_1455372chr9_136888009_+SINEAluName=AluSq
ADediting_1455373chr9_136888310_+SINEAluName=AluYc
ADediting_1455374chr9_136888316_+SINEAluName=AluYc
ADediting_1455375chr9_136888320_+SINEAluName=AluYc
ADediting_1455376chr9_136888337_+SINEAluName=AluYc
ADediting_1455377chr9_136888381_+SINEAluName=AluYc
ADediting_1455378chr9_136888383_+SINEAluName=AluYc
ADediting_1455379chr9_136888927_+SINEAluName=AluY
ADediting_1455380chr9_136888995_+SINEAluName=AluY
ADediting_1455381chr9_136889306_+SINEAluName=AluSp
ADediting_1455382chr9_136889377_+SINEAluName=AluSp
ADediting_1455383chr9_136889413_+SINEAluName=AluSp
ADediting_1455384chr9_136890971_+SINEAluName=AluJb
ADediting_1455385chr9_136890984_+SINEAluName=AluJb
ADediting_1455386chr9_136891030_+SINEAluName=AluJb
ADediting_1455387chr9_136891047_+SINEAluName=AluJb
ADediting_1455388chr9_136891057_+SINEAluName=AluJb
ADediting_1455389chr9_136891075_+SINEAluName=AluJb
ADediting_1455390chr9_136891134_+SINEAluName=AluSx3
ADediting_1455391chr9_136891170_+SINEAluName=AluSx3
ADediting_1455392chr9_136891178_+SINEAluName=AluSx3
ADediting_1455393chr9_136891189_+SINEAluName=AluSx3
ADediting_1455394chr9_136891226_+SINEAluName=AluSx3
ADediting_1455395chr9_136891238_+SINEAluName=AluSx3
ADediting_1455396chr9_136891284_+SINEAluName=AluSx3
ADediting_1455397chr9_136891307_+SINEAluName=AluSx3
ADediting_1455398chr9_136891310_+SINEAluName=AluSx3
ADediting_1455399chr9_136891319_+SINEAluName=AluSx3
ADediting_1455400chr9_136891344_+SINEAluName=AluSx3
ADediting_1455401chr9_136891370_+SINEAluName=AluSx3
ADediting_1455402chr9_136891382_+SINEAluName=AluSx3
ADediting_1455403chr9_136891385_+SINEAluName=AluSx3
ADediting_1455404chr9_136891433_+SINEAluName=AluJb
ADediting_1455405chr9_136891444_+SINEAluName=AluJb
ADediting_1455406chr9_136891453_+SINEAluName=AluJb
ADediting_1455407chr9_136891478_+SINEAluName=AluJb
ADediting_1455408chr9_136891479_+SINEAluName=AluJb
ADediting_1455409chr9_136891483_+SINEAluName=AluJb
ADediting_1455410chr9_136891766_+SINEAluName=AluSp
ADediting_1455411chr9_136891802_+SINEAluName=AluSp
ADediting_1455412chr9_136891821_+SINEAluName=AluSp
ADediting_1455413chr9_136891822_+SINEAluName=AluSp
ADediting_1455414chr9_136891839_+SINEAluName=AluSp
ADediting_1455415chr9_136891847_+SINEAluName=AluSp
ADediting_1455416chr9_136891851_+SINEAluName=AluSp
ADediting_1455417chr9_136891861_+SINEAluName=AluSp
ADediting_1455418chr9_136891863_+SINEAluName=AluSp
ADediting_1455419chr9_136891901_+SINEAluName=AluSp
ADediting_1455420chr9_136891904_+SINEAluName=AluSp
ADediting_1455421chr9_136891907_+SINEAluName=AluSp
ADediting_1455422chr9_136891920_+SINEAluName=AluSp
ADediting_1455423chr9_136891930_+SINEAluName=AluSp
ADediting_1455424chr9_136891961_+SINEAluName=AluSp
ADediting_1455425chr9_136891970_+SINEAluName=AluSp
ADediting_1455426chr9_136891979_+SINEAluName=AluSp
ADediting_1455427chr9_136891980_+SINEAluName=AluSp
ADediting_1455428chr9_136891992_+SINEAluName=AluSp
ADediting_1455429chr9_136891998_+SINEAluName=AluSp
ADediting_1455430chr9_136892186_+SINEAluName=AluY
ADediting_1455431chr9_136892208_+SINEAluName=AluY
ADediting_1455432chr9_136892209_+SINEAluName=AluY
ADediting_1455433chr9_136892304_+SINEAluName=AluY
ADediting_1455434chr9_136892310_+SINEAluName=AluY
ADediting_1455435chr9_136892317_+SINEAluName=AluY
ADediting_1455436chr9_136892343_+SINEAluName=AluY
ADediting_1455437chr9_136892349_+SINEAluName=AluY
ADediting_1455438chr9_136892353_+SINEAluName=AluY
ADediting_1455439chr9_136892370_+SINEAluName=AluY
ADediting_1455440chr9_136892384_+SINEAluName=AluY
ADediting_1455441chr9_136892414_+SINEAluName=AluY
ADediting_1455442chr9_136892608_+SINEAluName=AluSx1
ADediting_1455443chr9_136892622_+SINEAluName=AluSx1
ADediting_1455444chr9_136892624_+SINEAluName=AluSx1
ADediting_1455445chr9_136892625_+SINEAluName=AluSx1
ADediting_1455446chr9_136892655_+SINEAluName=AluSx1
ADediting_1455447chr9_136892660_+SINEAluName=AluSx1
ADediting_1455448chr9_136892670_+SINEAluName=AluSx1
ADediting_1455449chr9_136892694_+SINEAluName=AluSx1
ADediting_1455450chr9_136892703_+SINEAluName=AluSx1
ADediting_1455451chr9_136892718_+SINEAluName=AluSx1
ADediting_1455452chr9_136892720_+SINEAluName=AluSx1
ADediting_1455453chr9_136892721_+SINEAluName=AluSx1
ADediting_1455454chr9_136892733_+SINEAluName=AluSx1
ADediting_1455455chr9_136892759_+SINEAluName=AluSx1
ADediting_1455456chr9_136892760_+SINEAluName=AluSx1
ADediting_1455457chr9_136892769_+SINEAluName=AluSx1
ADediting_1455458chr9_136892786_+SINEAluName=AluSx1
ADediting_1455459chr9_136892792_+SINEAluName=AluSx1
ADediting_1455460chr9_136892801_+SINEAluName=AluSx1
ADediting_1455461chr9_136892831_+SINEAluName=AluSx1
ADediting_1455462chr9_136892833_+SINEAluName=AluSx1
ADediting_1455463chr9_136893849_+SINEAluName=AluSg
ADediting_1455464chr9_136893850_+SINEAluName=AluSg
ADediting_1455465chr9_136893867_+SINEAluName=AluSg
ADediting_1455466chr9_136893879_+SINEAluName=AluSg
ADediting_1455467chr9_136893970_+SINEAluName=AluSg
ADediting_1455468chr9_136894010_+SINEAluName=AluSg
ADediting_1455469chr9_136894108_+SINEAluName=AluSc
ADediting_1455470chr9_136894126_+SINEAluName=AluSc
ADediting_1455471chr9_136894127_+SINEAluName=AluSc
ADediting_1455472chr9_136894147_+SINEAluName=AluSc
ADediting_1455473chr9_136894150_+SINEAluName=AluSc
ADediting_1455474chr9_136894151_+SINEAluName=AluSc
ADediting_1455475chr9_136894176_+SINEAluName=AluSc
ADediting_1455476chr9_136894236_+SINEAluName=AluSc
ADediting_1455477chr9_136894247_+SINEAluName=AluSc
ADediting_1455478chr9_136894307_+SINEAluName=AluSc
ADediting_1455479chr9_136894319_+SINEAluName=AluSc
ADediting_1455480chr9_136894321_+SINEAluName=AluSc
ADediting_1455481chr9_136894337_+SINEAluName=AluSc
ADediting_1455483chr9_136894839_+SINEAluName=FAM
ADediting_1455484chr9_136895581_+SINEAluName=AluSx1
ADediting_1455485chr9_136895593_+SINEAluName=AluSx1
ADediting_1455486chr9_136895599_+SINEAluName=AluSx1
ADediting_1455487chr9_136895600_+SINEAluName=AluSx1
ADediting_1455488chr9_136895637_+SINEAluName=AluSx1
ADediting_1455489chr9_136895642_+SINEAluName=AluSx1
ADediting_1455490chr9_136895650_+SINEAluName=AluSx1
ADediting_1455491chr9_136895651_+SINEAluName=AluSx1
ADediting_1455492chr9_136895656_+SINEAluName=AluSx1
ADediting_1455493chr9_136895665_+SINEAluName=AluSx1
ADediting_1455494chr9_136895666_+SINEAluName=AluSx1
ADediting_1455495chr9_136895689_+SINEAluName=AluSx1
ADediting_1455496chr9_136895695_+SINEAluName=AluSx1
ADediting_1455497chr9_136895697_+SINEAluName=AluSx1
ADediting_1455498chr9_136895699_+SINEAluName=AluSx1
ADediting_1455499chr9_136895702_+SINEAluName=AluSx1
ADediting_1455500chr9_136895722_+SINEAluName=AluSx1
ADediting_1455501chr9_136895738_+SINEAluName=AluSx1
ADediting_1455502chr9_136895761_+SINEAluName=AluSx1
ADediting_1455503chr9_136895770_+SINEAluName=AluSx1
ADediting_1455504chr9_136895774_+SINEAluName=AluSx1
ADediting_1455505chr9_136895811_+SINEAluName=AluSx1
ADediting_1455506chr9_136895821_+SINEAluName=AluSx1
ADediting_1455507chr9_136896694_+SINEAluName=AluY
ADediting_1455508chr9_136896738_+SINEAluName=AluY
ADediting_1455509chr9_136896748_+SINEAluName=AluY
ADediting_1455510chr9_136896750_+SINEAluName=AluY
ADediting_1455511chr9_136896815_+SINEAluName=AluY
ADediting_1455512chr9_136896819_+SINEAluName=AluY
ADediting_1455513chr9_136896822_+SINEAluName=AluY
ADediting_1455514chr9_136896870_+SINEAluName=AluY
ADediting_1455515chr9_136896877_+SINEAluName=AluY
ADediting_1455516chr9_136903123_+SINEAluName=AluSx1
ADediting_1455517chr9_136903134_+SINEAluName=AluSx1
ADediting_1455518chr9_136903233_+SINEAluName=AluSx1
ADediting_1455519chr9_136904437_+SINEAluName=AluY
ADediting_1455520chr9_136904539_+SINEAluName=AluY
ADediting_1455521chr9_136905998_+SINEAluName=AluY
ADediting_1455522chr9_136906011_+SINEAluName=AluY
ADediting_1455523chr9_136908763_+SINEAluName=AluY
ADediting_1455524chr9_136908771_+SINEAluName=AluY
ADediting_1455525chr9_136908795_+SINEAluName=AluY
ADediting_1455526chr9_136911321_+SINEAluName=AluSp
ADediting_1455527chr9_136911345_+SINEAluName=AluSp
ADediting_1455528chr9_136911364_+SINEAluName=AluSp
ADediting_1455529chr9_136911382_+SINEAluName=AluSp
ADediting_1455530chr9_136911394_+SINEAluName=AluSp
ADediting_1455531chr9_136911422_+SINEAluName=AluSp
ADediting_1455532chr9_136912279_+SINEAluName=AluSg7
ADediting_1455533chr9_136912434_+SINEAluName=AluSg7
ADediting_1455534chr9_136912598_+SINEAluName=AluSz6
ADediting_1455535chr9_136912660_+SINEAluName=AluSz6
ADediting_1455536chr9_136912681_+SINEAluName=AluSz6
ADediting_1455537chr9_136912690_+SINEAluName=AluSz6
ADediting_1455538chr9_136912716_+SINEAluName=AluSz6
ADediting_1455539chr9_136912747_+SINEAluName=AluSz6
ADediting_1455540chr9_136912895_+SINEAluName=AluSx
ADediting_1455541chr9_136912899_+SINEAluName=AluSx
ADediting_1455542chr9_136912904_+SINEAluName=AluSx
ADediting_1455543chr9_136912931_+SINEAluName=AluSx
ADediting_1455544chr9_136912954_+SINEAluName=AluSx
ADediting_1455545chr9_136912955_+SINEAluName=AluSx
ADediting_1455546chr9_136912990_+SINEAluName=AluSx
ADediting_1455547chr9_136913017_+SINEAluName=AluSx
ADediting_1455548chr9_136913397_+SINEAluName=AluSx3
ADediting_1455549chr9_136913398_+SINEAluName=AluSx3
ADediting_1455550chr9_136913415_+SINEAluName=AluSx3
ADediting_1455551chr9_136913559_+SINEAluName=AluSx3
ADediting_1455552chr9_136924346_+SINEAluName=AluJb
ADediting_1455553chr9_136924378_+SINEAluName=AluJb
ADediting_1455554chr9_136924406_+SINEAluName=AluJb
ADediting_1455555chr9_136924463_+SINEAluName=AluJb
ADediting_1455556chr9_136924801_+SINEAluName=AluSx3
ADediting_1455557chr9_136924820_+SINEAluName=AluSx3
ADediting_1593117chr9_136888054_+SINEAluName=AluSq
ADediting_1593118chr9_136888060_+SINEAluName=AluSq
ADediting_1593119chr9_136888080_+SINEAluName=AluSq
ADediting_1593120chr9_136888091_+SINEAluName=AluSq
ADediting_1593121chr9_136888391_+SINEAluName=AluYc
ADediting_1593122chr9_136891506_+SINEAluName=AluJb
ADediting_1593123chr9_136891518_+SINEAluName=AluJb
ADediting_1593124chr9_136891534_+SINEAluName=AluJb
ADediting_1593125chr9_136891815_+SINEAluName=AluSp
ADediting_1593126chr9_136891848_+SINEAluName=AluSp
ADediting_1593127chr9_136892405_+SINEAluName=AluY
ADediting_1593128chr9_136892791_+SINEAluName=AluSx1
ADediting_1593129chr9_136893889_+SINEAluName=AluSg
ADediting_1593130chr9_136893950_+SINEAluName=AluSg
ADediting_1593131chr9_136894022_+SINEAluName=AluSg
ADediting_1593132chr9_136894188_+SINEAluName=AluSc
ADediting_1593133chr9_136894230_+SINEAluName=AluSc
ADediting_1593134chr9_136894244_+SINEAluName=AluSc
ADediting_1593135chr9_136895676_+SINEAluName=AluSx1
ADediting_1593136chr9_136895681_+SINEAluName=AluSx1
ADediting_1593137chr9_136895698_+SINEAluName=AluSx1
ADediting_1593138chr9_136896661_+SINEAluName=AluY
ADediting_1593139chr9_136896807_+SINEAluName=AluY
ADediting_1593140chr9_136903125_+SINEAluName=AluSx1
ADediting_1593141chr9_136905772_+SINEAluName=AluJb
ADediting_1593142chr9_136912971_+SINEAluName=AluSx

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RNA A-to-I editing events in the alternative splicing sites for TRAF2

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_1455476chr9_136894236_+136894218:1368942403ss2iTGTATTTTTAGTAGAGACAGGGT-13.20TGTATTTTTAGTAGAGACGGGGT-21.16
ESADediting_1593133chr9_136894230_+136894218:1368942403ss8iTGTATTTTTAGTAGAGACAGGGT-13.20TGTATTTTTAGTGGAGACAGGGT-7.65

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TRAF2

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.
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check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
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check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for TRAF2

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TRAF2


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_98289chr1_32086992_+ENSG00000127191.18ENST00000247668.7TRAF2-201hsa-miR-5585-3pchr91369265941369266018mer-1a136926578136926601143-11.39

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TRAF2

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for TRAF2

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1455363chr9_136887894_+5.75209288218128e-050.3223422478623283.64217742964898e-050.3303850825511820.994672686705619-0.000549761234152413
CERADediting_1455365chr9_136887925_+0.001659552304201260.2546891192725765.99847083839496e-060.3601180962744380.3734801329550560.0731807259605936
CERADediting_1455367chr9_136887949_+0.0139066629285920.2004648435330999.88431445821931e-080.4184633720369230.1608732115325080.115066263262144
CERADediting_1455370chr9_136887987_+0.01916147970024560.1910867772868897.99140551662622e-050.3164119234861180.1909167862314180.107376523080538
CERADediting_1455371chr9_136887999_+0.003123568070359870.2397755202890572.23615535055755e-060.3752015442585220.07656398145304180.145047624911139
CERADediting_1455373chr9_136888310_+2.56910455885559e-090.4624023190732065.80074381120851e-120.5242057714066710.2344988344211550.097653893610764
CERADediting_1455374chr9_136888316_+3.47664910756999e-060.368549536369861.26598961586304e-080.4439637620471780.3070481194917120.0839548436944017
CERADediting_1455375chr9_136888320_+1.89312254932685e-050.3415246076166284.40283025195314e-110.5049876566584820.2330064654583930.0979645605012579
CERADediting_1455376chr9_136888337_+9.05795165506964e-050.3141193953217946.15116626427888e-090.4524443532488310.1817702428496570.109616909543948
CERADediting_1455377chr9_136888381_+0.01058352513766020.2081593225545870.0001186752224113230.3091111184010820.02995969697548760.177307151050942
CERADediting_1455382chr9_136889377_+0.01320312131281750.2019477324769175.74076758449623e-060.3608057970526520.03597917558872030.171397201068647
CERADediting_1455404chr9_136891433_+0.000257462780487580.2942346568878756.52999067216751e-060.358783927956950.04628584516917680.162983372805836
CERADediting_1593121chr9_136888391_+0.004129755314131680.2328967034686162.18001196515609e-050.3391584110957270.5539007729811880.0487092526693918

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC2.5385434256549e-240.5346969655527487.84811887634029e-320.6010578308705441.98741938148143e-110.368899964218332
AC1.63851916024022e-240.5866632005950589.42680707763965e-190.5204104038051311.13204848039076e-140.462779166565148
PCC5.27880720271029e-140.5093657551417082.84710199368049e-170.561653064842080.02052715959550230.167534392459542
CER2.3969471820762e-070.4067864856660172.66355744870633e-200.6624271131478680.04832733716576370.161506582581347
TCX1.3020772751849e-060.3831574965515363.2687407851355e-060.3694879378577284.83075648223151e-050.325441197095641
FP4.36663216096924e-110.4682565811214844.65421991183895e-120.4883938037999811.63047694843562e-080.407621516973806
IFG9.66287536608391e-070.8092915918357395.24331292618911e-070.8200501041169870.02205194902887680.455733208072676
STG6.96138463449824e-100.61059085947262.92666200545465e-060.4850434517098230.01828839292261820.256977938123862

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Relation with AD stages for TRAF2

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1455371chr9_136887999_+0.0007469995346482180.31960954371545
CERADediting_1455373chr9_136888310_+0.000104543697856680.36463798733008
CERADediting_1455375chr9_136888320_+0.0006216440537326890.324116834450629

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER0.0002856359694984370.342470043434083
TCX8.43627218074903e-050.372457734867101

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RelatedDrugs for TRAF2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TRAF2

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource