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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited versus non-edited samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with AD stages

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene


Gene summary for TFE3

check button Gene summary
Gene informationGene symbol

TFE3

Gene ID

7030

Gene nametranscription factor binding to IGHM enhancer 3
SynonymsRCCP2|RCCX1|TFEA|bHLHe33
Cytomap

Xp11.23

Type of geneprotein-coding
Descriptiontranscription factor E3class E basic helix-loop-helix protein 33transcription factor E family, member Atranscription factor for IgH enhancertranscription factor for immunoglobulin heavy-chain enhancer 3
Modification date20200327
UniProtAcc

P19532,

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for TFE3

check buttonRNA A-to-I editing events in the ROSMAP, MSBB, and Mayo data sets based on Ensembl gene isoform structure.
* This pie chart shows the number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
all structure

check button RNA editing frequencies across three data sets.
boxplot

check buttonThe number of RNA A-to-I editing events in different types of transcripts (# event, percentage).
boxplot

check button RNA A-to-I editing events in AD.
ADediting_1502560(49033171, -), ADediting_1502561(49034992, -), ADediting_1502562(49035036, -), ADediting_1502563(49035054, -), ADediting_1502564(49035066, -), ADediting_1502565(49035067, -), ADediting_1502566(49035128, -), ADediting_1502567(49035145, -), ADediting_1502568(49035148, -), ADediting_1502569(49035197, -), ADediting_1502570(49035198, -), ADediting_1502571(49035200, -), ADediting_1502572(49035210, -), ADediting_1502573(49035213, -), ADediting_1502574(49035214, -), ADediting_1502575(49035222, -), ADediting_1502576(49035235, -), ADediting_1502577(49035239, -), ADediting_1502578(49035253, -), ADediting_1502579(49035265, -), ADediting_1502580(49035439, -), ADediting_1502581(49035474, -), ADediting_1502582(49035479, -), ADediting_1502583(49035492, -), ADediting_1502584(49035503, -), ADediting_1502585(49035512, -), ADediting_1502586(49035518, -), ADediting_1502587(49035535, -), ADediting_1502588(49035539, -), ADediting_1502589(49035545, -), ADediting_1502590(49035571, -), ADediting_1502591(49035582, -), ADediting_1502592(49035586, -), ADediting_1502593(49035588, -), ADediting_1502594(49035591, -), ADediting_1502595(49035603, -), ADediting_1502596(49035608, -), ADediting_1502597(49035610, -), ADediting_1502598(49035612, -), ADediting_1502599(49035636, -), ADediting_1502600(49035674, -), ADediting_1502601(49035679, -), ADediting_1502602(49035680, -), ADediting_1502603(49035686, -), ADediting_1502604(49035688, -), ADediting_1502605(49035698, -), ADediting_1502606(49035702, -), ADediting_1502607(49035907, -), ADediting_1502608(49035913, -), ADediting_1502609(49035925, -), ADediting_1502610(49035926, -), ADediting_1502611(49035940, -), ADediting_1502612(49035965, -), ADediting_1502613(49035990, -), ADediting_1502614(49035998, -), ADediting_1502615(49036004, -), ADediting_1502616(49036007, -), ADediting_1502617(49036013, -), ADediting_1502618(49036022, -), ADediting_1502619(49036023, -), ADediting_1502620(49036049, -), ADediting_1502621(49036058, -), ADediting_1502622(49036059, -), ADediting_1502623(49036063, -), ADediting_1502624(49036071, -), ADediting_1502625(49036076, -), ADediting_1502626(49036088, -), ADediting_1502627(49036089, -), ADediting_1502628(49036102, -), ADediting_1502629(49036109, -), ADediting_1502630(49036114, -), ADediting_1502631(49036124, -), ADediting_1502632(49036165, -), ADediting_1502633(49036169, -), ADediting_1502634(49036285, -), ADediting_1502635(49036343, -), ADediting_1502636(49036345, -), ADediting_1502637(49036350, -), ADediting_1502638(49036355, -), ADediting_1502639(49036358, -), ADediting_1502640(49036359, -), ADediting_1502641(49036380, -), ADediting_1502642(49036384, -), ADediting_1502643(49036427, -), ADediting_1502644(49036432, -), ADediting_1502645(49036542, -), ADediting_1502646(49036548, -), ADediting_1502647(49036560, -), ADediting_1502648(49036561, -), ADediting_1502649(49036599, -), ADediting_1502650(49036600, -), ADediting_1502651(49036610, -), ADediting_1502652(49036636, -), ADediting_1502653(49036639, -), ADediting_1502654(49036680, -), ADediting_1502655(49036689, -), ADediting_1502656(49036690, -), ADediting_1502657(49036719, -), ADediting_1502658(49036720, -), ADediting_1502659(49036725, -), ADediting_1502660(49036726, -), ADediting_1502661(49036755, -), ADediting_1502662(49036763, -), ADediting_1502663(49036796, -), ADediting_1502664(49037078, -), ADediting_1502665(49037604, -), ADediting_1502666(49037647, -), ADediting_1595405(49035137, -), ADediting_1595406(49035575, -), ADediting_1595407(49035584, -), ADediting_1595408(49035898, -), ADediting_1595409(49036305, -), ADediting_1595410(49036332, -), ADediting_1595411(49036605, -), ADediting_1595412(49036645, -), ADediting_1595413(49036664, -), ADediting_1595414(49036715, -), ADediting_1595415(49036795, -), ADediting_1595416(49037166, -), ADediting_1675236(49037623, -),

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RNA editing positional annotations for TFE3 using Annovar

check button Protein coding RNA editing(s).
ADeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
ADeditome IDPositionVariant type
ADediting_1502560chrX_49033171_-intronic
ADediting_1502561chrX_49034992_-intronic
ADediting_1502562chrX_49035036_-intronic
ADediting_1502563chrX_49035054_-intronic
ADediting_1502564chrX_49035066_-intronic
ADediting_1502565chrX_49035067_-intronic
ADediting_1502566chrX_49035128_-intronic
ADediting_1502567chrX_49035145_-intronic
ADediting_1502568chrX_49035148_-intronic
ADediting_1502569chrX_49035197_-intronic
ADediting_1502570chrX_49035198_-intronic
ADediting_1502571chrX_49035200_-intronic
ADediting_1502572chrX_49035210_-intronic
ADediting_1502573chrX_49035213_-intronic
ADediting_1502574chrX_49035214_-intronic
ADediting_1502575chrX_49035222_-intronic
ADediting_1502576chrX_49035235_-intronic
ADediting_1502577chrX_49035239_-intronic
ADediting_1502578chrX_49035253_-intronic
ADediting_1502579chrX_49035265_-intronic
ADediting_1502580chrX_49035439_-intronic
ADediting_1502581chrX_49035474_-intronic
ADediting_1502582chrX_49035479_-intronic
ADediting_1502583chrX_49035492_-intronic
ADediting_1502584chrX_49035503_-intronic
ADediting_1502585chrX_49035512_-intronic
ADediting_1502586chrX_49035518_-intronic
ADediting_1502587chrX_49035535_-intronic
ADediting_1502588chrX_49035539_-intronic
ADediting_1502589chrX_49035545_-intronic
ADediting_1502590chrX_49035571_-intronic
ADediting_1502591chrX_49035582_-intronic
ADediting_1502592chrX_49035586_-intronic
ADediting_1502593chrX_49035588_-intronic
ADediting_1502594chrX_49035591_-intronic
ADediting_1502595chrX_49035603_-intronic
ADediting_1502596chrX_49035608_-intronic
ADediting_1502597chrX_49035610_-intronic
ADediting_1502598chrX_49035612_-intronic
ADediting_1502599chrX_49035636_-intronic
ADediting_1502600chrX_49035674_-intronic
ADediting_1502601chrX_49035679_-intronic
ADediting_1502602chrX_49035680_-intronic
ADediting_1502603chrX_49035686_-intronic
ADediting_1502604chrX_49035688_-intronic
ADediting_1502605chrX_49035698_-intronic
ADediting_1502606chrX_49035702_-intronic
ADediting_1502607chrX_49035907_-intronic
ADediting_1502608chrX_49035913_-intronic
ADediting_1502609chrX_49035925_-intronic
ADediting_1502610chrX_49035926_-intronic
ADediting_1502611chrX_49035940_-intronic
ADediting_1502612chrX_49035965_-intronic
ADediting_1502613chrX_49035990_-intronic
ADediting_1502614chrX_49035998_-intronic
ADediting_1502615chrX_49036004_-intronic
ADediting_1502616chrX_49036007_-intronic
ADediting_1502617chrX_49036013_-intronic
ADediting_1502618chrX_49036022_-intronic
ADediting_1502619chrX_49036023_-intronic
ADediting_1502620chrX_49036049_-intronic
ADediting_1502621chrX_49036058_-intronic
ADediting_1502622chrX_49036059_-intronic
ADediting_1502623chrX_49036063_-intronic
ADediting_1502624chrX_49036071_-intronic
ADediting_1502625chrX_49036076_-intronic
ADediting_1502626chrX_49036088_-intronic
ADediting_1502627chrX_49036089_-intronic
ADediting_1502628chrX_49036102_-intronic
ADediting_1502629chrX_49036109_-intronic
ADediting_1502630chrX_49036114_-intronic
ADediting_1502631chrX_49036124_-intronic
ADediting_1502632chrX_49036165_-intronic
ADediting_1502633chrX_49036169_-intronic
ADediting_1502634chrX_49036285_-intronic
ADediting_1502635chrX_49036343_-intronic
ADediting_1502636chrX_49036345_-intronic
ADediting_1502637chrX_49036350_-intronic
ADediting_1502638chrX_49036355_-intronic
ADediting_1502639chrX_49036358_-intronic
ADediting_1502640chrX_49036359_-intronic
ADediting_1502641chrX_49036380_-intronic
ADediting_1502642chrX_49036384_-intronic
ADediting_1502643chrX_49036427_-intronic
ADediting_1502644chrX_49036432_-intronic
ADediting_1502645chrX_49036542_-intronic
ADediting_1502646chrX_49036548_-intronic
ADediting_1502647chrX_49036560_-intronic
ADediting_1502648chrX_49036561_-intronic
ADediting_1502649chrX_49036599_-intronic
ADediting_1502650chrX_49036600_-intronic
ADediting_1502651chrX_49036610_-intronic
ADediting_1502652chrX_49036636_-intronic
ADediting_1502653chrX_49036639_-intronic
ADediting_1502654chrX_49036680_-intronic
ADediting_1502655chrX_49036689_-intronic
ADediting_1502656chrX_49036690_-intronic
ADediting_1502657chrX_49036719_-intronic
ADediting_1502658chrX_49036720_-intronic
ADediting_1502659chrX_49036725_-intronic
ADediting_1502660chrX_49036726_-intronic
ADediting_1502661chrX_49036755_-intronic
ADediting_1502662chrX_49036763_-intronic
ADediting_1502663chrX_49036796_-intronic
ADediting_1502664chrX_49037078_-intronic
ADediting_1502665chrX_49037604_-intronic
ADediting_1502666chrX_49037647_-intronic
ADediting_1595405chrX_49035137_-intronic
ADediting_1595406chrX_49035575_-intronic
ADediting_1595407chrX_49035584_-intronic
ADediting_1595408chrX_49035898_-intronic
ADediting_1595409chrX_49036305_-intronic
ADediting_1595410chrX_49036332_-intronic
ADediting_1595411chrX_49036605_-intronic
ADediting_1595412chrX_49036645_-intronic
ADediting_1595413chrX_49036664_-intronic
ADediting_1595414chrX_49036715_-intronic
ADediting_1595415chrX_49036795_-intronic
ADediting_1595416chrX_49037166_-intronic
ADediting_1675236chrX_49037623_-intronic

check button Repat-regional RNA editing(s).
ADeditome IDPositionRepeat familyRepeat sub familyRepeat name
ADediting_1502560chrX_49033171_-SINEAluName=Alu
ADediting_1502562chrX_49035036_-SINEAluName=AluSz
ADediting_1502563chrX_49035054_-SINEAluName=AluSz
ADediting_1502564chrX_49035066_-SINEAluName=AluSz
ADediting_1502565chrX_49035067_-SINEAluName=AluSz
ADediting_1502566chrX_49035128_-SINEAluName=AluSz
ADediting_1502567chrX_49035145_-SINEAluName=AluSz
ADediting_1502568chrX_49035148_-SINEAluName=AluSz
ADediting_1502569chrX_49035197_-SINEAluName=AluSz
ADediting_1502570chrX_49035198_-SINEAluName=AluSz
ADediting_1502571chrX_49035200_-SINEAluName=AluSz
ADediting_1502572chrX_49035210_-SINEAluName=AluSz
ADediting_1502573chrX_49035213_-SINEAluName=AluSz
ADediting_1502574chrX_49035214_-SINEAluName=AluSz
ADediting_1502575chrX_49035222_-SINEAluName=AluSz
ADediting_1502576chrX_49035235_-SINEAluName=AluSz
ADediting_1502577chrX_49035239_-SINEAluName=AluSz
ADediting_1502578chrX_49035253_-SINEAluName=AluSz
ADediting_1502579chrX_49035265_-SINEAluName=AluSz
ADediting_1502580chrX_49035439_-SINEAluName=AluY
ADediting_1502581chrX_49035474_-SINEAluName=AluY
ADediting_1502582chrX_49035479_-SINEAluName=AluY
ADediting_1502583chrX_49035492_-SINEAluName=AluY
ADediting_1502584chrX_49035503_-SINEAluName=AluY
ADediting_1502585chrX_49035512_-SINEAluName=AluY
ADediting_1502586chrX_49035518_-SINEAluName=AluY
ADediting_1502587chrX_49035535_-SINEAluName=AluY
ADediting_1502588chrX_49035539_-SINEAluName=AluY
ADediting_1502589chrX_49035545_-SINEAluName=AluY
ADediting_1502590chrX_49035571_-SINEAluName=AluY
ADediting_1502591chrX_49035582_-SINEAluName=AluY
ADediting_1502592chrX_49035586_-SINEAluName=AluY
ADediting_1502593chrX_49035588_-SINEAluName=AluY
ADediting_1502594chrX_49035591_-SINEAluName=AluY
ADediting_1502595chrX_49035603_-SINEAluName=AluY
ADediting_1502596chrX_49035608_-SINEAluName=AluY
ADediting_1502597chrX_49035610_-SINEAluName=AluY
ADediting_1502598chrX_49035612_-SINEAluName=AluY
ADediting_1502599chrX_49035636_-SINEAluName=AluY
ADediting_1502600chrX_49035674_-SINEAluName=AluY
ADediting_1502601chrX_49035679_-SINEAluName=AluY
ADediting_1502602chrX_49035680_-SINEAluName=AluY
ADediting_1502603chrX_49035686_-SINEAluName=AluY
ADediting_1502604chrX_49035688_-SINEAluName=AluY
ADediting_1502605chrX_49035698_-SINEAluName=AluY
ADediting_1502606chrX_49035702_-SINEAluName=AluY
ADediting_1502607chrX_49035907_-SINEAluName=AluJb
ADediting_1502608chrX_49035913_-SINEAluName=AluJb
ADediting_1502609chrX_49035925_-SINEAluName=AluJb
ADediting_1502610chrX_49035926_-SINEAluName=AluJb
ADediting_1502611chrX_49035940_-SINEAluName=AluJb
ADediting_1502612chrX_49035965_-SINEAluName=AluJb
ADediting_1502613chrX_49035990_-SINEAluName=AluJb
ADediting_1502614chrX_49035998_-SINEAluName=AluJb
ADediting_1502615chrX_49036004_-SINEAluName=AluJb
ADediting_1502616chrX_49036007_-SINEAluName=AluJb
ADediting_1502617chrX_49036013_-SINEAluName=AluJb
ADediting_1502618chrX_49036022_-SINEAluName=AluJb
ADediting_1502619chrX_49036023_-SINEAluName=AluJb
ADediting_1502620chrX_49036049_-SINEAluName=AluJb
ADediting_1502621chrX_49036058_-SINEAluName=AluJb
ADediting_1502622chrX_49036059_-SINEAluName=AluJb
ADediting_1502623chrX_49036063_-SINEAluName=AluJb
ADediting_1502624chrX_49036071_-SINEAluName=AluJb
ADediting_1502625chrX_49036076_-SINEAluName=AluJb
ADediting_1502626chrX_49036088_-SINEAluName=AluJb
ADediting_1502627chrX_49036089_-SINEAluName=AluJb
ADediting_1502628chrX_49036102_-SINEAluName=AluJb
ADediting_1502629chrX_49036109_-SINEAluName=AluJb
ADediting_1502630chrX_49036114_-SINEAluName=AluJb
ADediting_1502631chrX_49036124_-SINEAluName=AluJb
ADediting_1502632chrX_49036165_-SINEAluName=AluJb
ADediting_1502633chrX_49036169_-SINEAluName=AluJb
ADediting_1502634chrX_49036285_-SINEAluName=AluSq2
ADediting_1502635chrX_49036343_-SINEAluName=AluSq2
ADediting_1502636chrX_49036345_-SINEAluName=AluSq2
ADediting_1502637chrX_49036350_-SINEAluName=AluSq2
ADediting_1502638chrX_49036355_-SINEAluName=AluSq2
ADediting_1502639chrX_49036358_-SINEAluName=AluSq2
ADediting_1502640chrX_49036359_-SINEAluName=AluSq2
ADediting_1502641chrX_49036380_-SINEAluName=AluSq2
ADediting_1502642chrX_49036384_-SINEAluName=AluSq2
ADediting_1502643chrX_49036427_-SINEAluName=AluSq2
ADediting_1502644chrX_49036432_-SINEAluName=AluSq2
ADediting_1502645chrX_49036542_-SINEAluName=AluSc8
ADediting_1502646chrX_49036548_-SINEAluName=AluSc8
ADediting_1502647chrX_49036560_-SINEAluName=AluSc8
ADediting_1502648chrX_49036561_-SINEAluName=AluSc8
ADediting_1502649chrX_49036599_-SINEAluName=AluSc8
ADediting_1502650chrX_49036600_-SINEAluName=AluSc8
ADediting_1502651chrX_49036610_-SINEAluName=AluSc8
ADediting_1502652chrX_49036636_-SINEAluName=AluSc8
ADediting_1502653chrX_49036639_-SINEAluName=AluSc8
ADediting_1502654chrX_49036680_-SINEAluName=AluSc8
ADediting_1502655chrX_49036689_-SINEAluName=AluSc8
ADediting_1502656chrX_49036690_-SINEAluName=AluSc8
ADediting_1502657chrX_49036719_-SINEAluName=AluSc8
ADediting_1502658chrX_49036720_-SINEAluName=AluSc8
ADediting_1502659chrX_49036725_-SINEAluName=AluSc8
ADediting_1502660chrX_49036726_-SINEAluName=AluSc8
ADediting_1502661chrX_49036755_-SINEAluName=AluSc8
ADediting_1502662chrX_49036763_-SINEAluName=AluSc8
ADediting_1502663chrX_49036796_-SINEAluName=AluSc8
ADediting_1502664chrX_49037078_-SINEAluName=AluSz
ADediting_1502665chrX_49037604_-SINEAluName=AluSg
ADediting_1502666chrX_49037647_-SINEAluName=AluSg
ADediting_1595405chrX_49035137_-SINEAluName=AluSz
ADediting_1595406chrX_49035575_-SINEAluName=AluY
ADediting_1595407chrX_49035584_-SINEAluName=AluY
ADediting_1595408chrX_49035898_-SINEAluName=AluJb
ADediting_1595409chrX_49036305_-SINEAluName=AluSq2
ADediting_1595410chrX_49036332_-SINEAluName=AluSq2
ADediting_1595411chrX_49036605_-SINEAluName=AluSc8
ADediting_1595412chrX_49036645_-SINEAluName=AluSc8
ADediting_1595413chrX_49036664_-SINEAluName=AluSc8
ADediting_1595414chrX_49036715_-SINEAluName=AluSc8
ADediting_1595415chrX_49036795_-SINEAluName=AluSc8
ADediting_1595416chrX_49037166_-SINEAluName=AluSz
ADediting_1675236chrX_49037623_-SINEAluName=AluSg

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RNA A-to-I editing events in the alternative splicing sites for TFE3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeADeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESADediting_1595411chrX_49036605_-49036603:490366115ss4iCAGGTTATC-0.23CAGGTTGTC-1.28

check button Differential pencent of spliced in (PSI) between RNA A-to-I edited and non-edited samples

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TFE3

check button Distribution of the averaged gene expression in AD and control with or without RNA A-to-I editing event.
* The grey color means N/A.

check button Distribution of the averaged gene isoform expression in AD and control with or without RNA A-to-I editing event.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

check button - Differentially expressed transcript between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

ADeditome IDChrPositoingSkipped exonENSGENSTs

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Protein coding region RNA A-to-I editings for TFE3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TFE3


check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1337757chr7_5495852_-ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-589-3pchrX49029628490296347mer-m84902962749029650148-18.37
ADediting_496066chr15_66496985_-ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-4512chrX49028810490288178mer-1a4902881049028831146-19.82
ADediting_496066chr15_66496985_-ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-4512chrX49029244490292507mer-m84902924349029266150-23.09
ADediting_496066chr15_66496985_-ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-4512chrX49029539490295468mer-1a4902953949029560146-20.2
ADediting_496066chr15_66496985_-ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-4512chrX49030092490300987mer-m84903009149030114155-29.51

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
ADeditom_IDPositionENSGENSTTranscript namemiRNA IDChromosomeTargtTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
ADediting_1391023chr8_140732605_-ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-151a-3pchrX49029722490297287mer-m84902972149029742146-18.61
ADediting_1535951chr14_100874558_+ENSG00000068323.17ENST00000315869.8TFE3-201hsa-miR-337-3pchrX49029522490295298mer-1a4902952249029543142-6.49

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TFE3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in miRNA.
ADeditom_IDENSTmir_IDEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in mRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

check button RNA A-to-I editing in lncRNA.
ADeditom_IDENSTEditing_InformationEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for TFE3

check button Correlation between ADAR gene expression and RNA editing frequency
TissueADeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
CERADediting_1502563chrX_49035054_-0.0003456491630212510.2883593057894621.1584519436352e-060.3848497215525410.7223480416167750.0292504401466466
CERADediting_1502566chrX_49035128_-6.2028323318782e-050.3209924524345288.27052347299024e-120.5209281256106960.001477625778365120.257334677846098
CERADediting_1502567chrX_49035145_-0.001181161996089480.262361703885753.61317461135367e-050.3305238065828060.01690039626827180.194807375172505
CERADediting_1502569chrX_49035197_-1.46491643991195e-050.3457762479417691.68586494674489e-070.4114786485105630.00150860075979560.256863979395454
CERADediting_1502572chrX_49035210_-0.0006719533270976510.2746113424206483.62130172729538e-050.3304848283597560.1117491003780550.130389782850022
CERADediting_1502576chrX_49035235_-0.001132273146407950.2632997972984864.13971384760584e-050.3281541480075920.06704266082465350.149940019890218
CERADediting_1502578chrX_49035253_-0.008858948851786430.2130369255260450.0001766810381168890.3015667606369880.0831254491543280.141955288287168
CERADediting_1502595chrX_49035603_-0.027588565336830.1799159526313410.0001241716312450330.3082630203364940.06310259098713180.152131442094997
CERADediting_1502596chrX_49035608_-0.02156980459196990.1875205773633561.31126645213764e-050.3475944712939820.04856651016623750.161336982566343
CERADediting_1502598chrX_49035612_-0.004018106263482390.2335804118436657.64375998949197e-070.3907942379617980.004101315479857560.233069270254674
CERADediting_1502600chrX_49035674_-0.0003157999243795520.2901742957093621.08902877435335e-080.4457520501382820.03703002328207590.1704526574739
CERADediting_1502601chrX_49035679_-0.0001505627064688290.3046239454289092.17848109655113e-080.4374303113941090.003723761653897770.235468313880599
CERADediting_1502602chrX_49035680_-0.001466096960457550.2575121715018788.13941383965636e-080.4209655260159040.01070020077886570.207855291642858
CERADediting_1502603chrX_49035686_-0.005988674718772110.2234309267491829.74130370145631e-050.3127798293143260.05703860756626730.155733903103907
CERADediting_1502608chrX_49035913_-3.16986635455659e-090.460034657671572.81925983960257e-100.4862647279665430.02573503051154490.182092127853955
CERADediting_1502611chrX_49035940_-6.83412004149129e-050.3192489086478731.57538064328314e-050.344577157274720.2158211096902880.101647500667804
TCXADediting_1502611chrX_49035940_-0.4242375387081790.06572475287874470.152394365791304-0.1174285349309631.15919207181408e-060.384840499771386
CERADediting_1502613chrX_49035990_-6.10815818838495e-070.393952949024878.7352127627653e-100.4742813000009550.06465081461445420.151257361567977
CERADediting_1502614chrX_49035998_-5.73753076363119e-060.3608146193552071.86776850291341e-090.4659604446649710.005554696238318280.225376996782597
CERADediting_1502615chrX_49036004_-7.58723259803925e-050.3173562627676391.81544679332522e-090.4662755785142930.01658532029238280.195359696259229
CERADediting_1502616chrX_49036007_-2.57619323613361e-050.3363331322098561.06812325297234e-080.4459815158102190.004188320649935880.232544677894214
CERADediting_1502617chrX_49036013_-7.31198894052651e-070.3914218485003921.21660884436845e-100.4948794557487680.0008623778672158720.269263106499001
CERADediting_1502618chrX_49036022_-0.0001252471114450360.3081011809396462.23186036932671e-070.4077437617206480.05339118066716330.158055508300405
CERADediting_1502619chrX_49036023_-0.03730227874291580.170211633229537.3876714086738e-060.3568338928783220.8060763690430860.0202112754127022
CERADediting_1502620chrX_49036049_-0.0296005510611940.1776907273530192.54129561925206e-050.3365649290030620.6485863772946040.0375106388012878
CERADediting_1502621chrX_49036058_-0.0002687797589959530.2933844265626313.36808128207126e-080.4320840068234640.0102869327106690.208945672835066
CERADediting_1502624chrX_49036071_-5.26572634869973e-060.3621538729761051.58532879247946e-090.467774502889770.009850762838927010.210139166582859
CERADediting_1502625chrX_49036076_-5.88159965014229e-050.3219445517561764.93818418670588e-100.4803829741661980.01782993171793230.193228483935926
CERADediting_1502628chrX_49036102_-3.9029627225315e-050.3291823535354288.47845341637938e-110.4985088369668580.06005281877513590.153905902468491
CERADediting_1502629chrX_49036109_-0.0001226439789565590.3084951658135395.68498980231927e-090.4533564688364690.06934944584216880.148705319384855
CERADediting_1502630chrX_49036114_-0.005080863074310560.2276634423419976.43414775203383e-050.3203350621570220.3052319443208680.0842695572753674
CERADediting_1502631chrX_49036124_-4.28600212506084e-080.4290866039638321.11178891787904e-120.5390238602933280.1924969961281380.106997444873315
CERADediting_1502634chrX_49036285_-0.0001587481349411820.3036159170785593.05157514607683e-100.4854405633062940.0002941860625196930.291590624459499
CERADediting_1502636chrX_49036345_-6.76096842732219e-080.4233370626741.97462527293365e-130.5537874504925791.11893544489636e-050.350177792152562
CERADediting_1502637chrX_49036350_-6.20614807025312e-070.3937298656992334.09240641490878e-100.4823667466066936.92511342862343e-060.357857198249449
CERADediting_1502638chrX_49036355_-1.10732642366572e-050.350346857273042.86222667524383e-110.5091726233343070.003240925756445040.238877831342599
CERADediting_1502640chrX_49036359_-1.48386297910149e-050.3455646473828512.2376566761464e-070.4077090202928480.003866055186434070.23453952061047
DLPFCADediting_1502643chrX_49036427_-0.1323892640229370.08565274635386920.3998682015019740.04798052963818139.35142397467924e-100.338642764625254
CERADediting_1502643chrX_49036427_-1.17919740056281e-050.3493259643186749.05852355056734e-120.5200814973960180.0003464263812372870.288314014306702
DLPFCADediting_1502645chrX_49036542_-0.5075055438235290.03777953290108050.485945613456121-0.03971881458979783.20500139521179e-080.307666578461029
CERADediting_1502645chrX_49036542_-0.002329783768876490.246799238370138.59751202642533e-050.3150763567202960.006554185843559270.221075619236113
CERADediting_1502646chrX_49036548_-0.0001616105756947680.3032748111941781.89286665503417e-060.3776759091528540.01296415207822180.202467172389151
CERADediting_1502652chrX_49036636_-0.0008291022081656840.2701138107399844.9354616464006e-050.3250623246289540.03590342256674070.17146618638408
TCXADediting_1502652chrX_49036636_-0.0861532343330860.140594053315570.9100344111338320.009303644115757030.0001394981131733820.306070948352382
CERADediting_1502653chrX_49036639_-0.0001249717600243810.3081424922642022.43984395799672e-050.3372562207906420.03320986906970540.174002902339557
TCXADediting_1502653chrX_49036639_-0.06643264064187990.1502723086322070.8555543468472940.01498773505885894.16703045442832e-070.399264852933696
CERADediting_1502655chrX_49036689_-0.006499924092590480.221293590228773.39417583575915e-050.3316064278677030.4038381963896540.0686538455192221
CERADediting_1502662chrX_49036763_-3.43352750935582e-070.401919366840881.18844226379227e-060.384480468543170.07715786531741820.144759135585273
CERADediting_1595410chrX_49036332_-0.002603236150845510.244163757262351.52008730844214e-080.441777345120950.01211686222888780.204379142648495

check button Correlation between ADAR gene expression and this gene's expression
TissueADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
DLPFC1.84701108717433e-610.7676089190677571.53747537513246e-570.7513225295173664.42090556948056e-110.362876271289311
AC4.31455576540752e-550.7921017826726961.64545854522846e-280.6251361331325341.77771888681677e-270.615682334393404
PCC1.41373558354774e-240.6528167823793241.94178713826665e-210.6171988686069565.263175476423e-080.381306179730533
CER3.40832831975104e-210.6738433239470958.44851480981344e-310.7709697427624824.82120213227301e-100.480636840846138
TCX3.9895306273741e-250.7186927442130398.89560931564599e-090.4481388087917548.35398067903375e-060.35487861452938
FP6.73402405600527e-090.4174703702723740.3371449306261250.07235710641397347.3097361896383e-110.463430588474651
IFG6.66760212236004e-070.8159028636191231.06393820446975e-060.8075336837446360.05560381822695160.387552048110629
PG0.03167442569975480.157611849440840.07958618047818790.1288751579079831.05731489194865e-070.377830708909964
STG4.43755303932478e-090.586883063383850.06784486288484820.2002143111939293.99109285206918e-050.432447053886649

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Relation with AD stages for TFE3

check button Correlation between AD stages and RNA editing frequency
TissueADeditomIDpositionP-valCoeff.
CERADediting_1502566chrX_49035128_-0.0001731966269423150.353707388744812
CERADediting_1502614chrX_49035998_-0.0001084720462195990.363852473184345
CERADediting_1502615chrX_49036004_-0.0002046665522857360.350003791519582
CERADediting_1502617chrX_49036013_-0.0001503749029532280.356806699718833
CERADediting_1502634chrX_49036285_-6.6046819216341e-070.457077832904151
CERADediting_1502636chrX_49036345_-2.43520246260101e-060.43574665809889
CERADediting_1502637chrX_49036350_-4.7955599586758e-060.424069874325155
CERADediting_1502638chrX_49036355_-4.62850351376016e-050.381493382658563
CERADediting_1502640chrX_49036359_-0.0002687904261306390.343858057333253
CERADediting_1502643chrX_49036427_-0.0005010232684614760.329322946526282
CERADediting_1502649chrX_49036599_-0.0009886154051158470.312596503264687
TCXADediting_1502611chrX_49035940_-1.79366389737788e-050.403525300550257
TCXADediting_1502632chrX_49036165_-0.0006669301371312410.325330054915641
TCXADediting_1502652chrX_49036636_-0.0007682216170764140.321818509071205
TCXADediting_1502653chrX_49036639_-0.0005102937052503130.331866064248832

check button Correlation between AD stages and this gene's expression
TissueP-valCoeff.
CER4.81305554403536e-060.424005936767311
TCX1.64321383816796e-070.482351189874987

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RelatedDrugs for TFE3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.0 2018-04-02)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TFE3

check button Diseases associated with this gene.
(DisGeNet 4.0)
GeneDisease IDDisease name# pubmedsSource